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MIYAGI Taeko  宮城 妙子

ORCIDConnect your ORCID iD *help
… Alternative Names

宮城 妙子  ミヤギ タエコ

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Researcher Number 50006110
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2014: 東北薬科大学, 分子生体膜研究所, 教授
2012 – 2013: 東北薬科大学, 薬学研究科(研究院), 教授
2010 – 2011: 東北薬科大学, 大学院・薬学研究科, 教授
2009: 宮城県立がんセンター研究所, 部長兼所長
2006 – 2009: Miyagi Cancer Center Research Institute, Division of Biochemistry, Institute Head, 生化学部, 所長兼部長 … More
2006: 宮城県がんセンター, 研究部, 部長
2006: Miyagi Caner Center, Research Institute, 部長
2005: 宮城県立がんセンター(研究所), 生化学部, 部長
2005: 宮城県立がんセンター
2005: Miyagi Prefectural Cancer Center, Director, 生化学部門, 部長(研究職)
2002 – 2005: 宮城県立がんセンター, 研究部, 部長
2002 – 2004: 宮城がんセンター研究所, 生化学部門, 部長(研究職)
2000: 宮城県立がんセンター, 研究所, 部長
1998 – 1999: 宮城県立がんセンター研究所, 部長
1994 – 1996: 宮城県立がんセンター研究所, 部長
1989 – 1992: 東北大学, 抗酸菌病研究所, 助教授
1987: 東北大学, 抗酸菌病研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Biological Sciences / Biological Sciences / 物質生物化学
Except Principal Investigator
Metabolomics / Metabolomics / Biological Sciences / Structural biochemistry
Keywords
Principal Investigator
シアリダーゼ / 遺伝子 / 糖鎖 / 酵素 / 癌 / ガングリオシド / がん治療 / 情報伝達 / siRNA / シアル酸 … More / cell adhesion / sialic acid / tumor-related antigen / gene / sialidase / sugar chain / enzyme / cancer / 接着 / 癌関連抗原 / 発生分化 / 神経科学 / 細胞浸潤 / 細胞接着 / グリオブラストーマ / NCAMポリシアル酸 / 神経突起形成 / 神経機能 / 糖尿病 / 腫瘍 / ムチン / アポトーシス / シグナル伝達 / 形質膜 … More
Except Principal Investigator
シアリダーゼ / ガングリオシド / トランスジェニックマウス / 糖脂質 / 糖転移酵素 / ノックアウトマウス / 形質膜 / 癌遺伝子 / 転写調節因子 / 肝発癌 / 糖蛋白質 / インスリン受容体基質1 / インスリン受容体 / インスリン抵抗性 / 糖尿病 / ganglioside / 遺伝子導入 / リソソーム / シアル酸 / 糖鎖 / 遺伝子クローニング / プロテアソ-ム / プロティンホスファタ-ゼ / Gタンパク質 / グルタチオンSートランスフェラ-ゼ / マ-カ-酵素 / 癌 / 癌マーカー / 精製 / insulin receptor substrate 1 / insulin receptor / insulin resistance / glucose tolerance / adenovirus vector / sialidase / diabetes / 耐糖能 / アデノウイルスベクター / Insulin receptor substrate 1 / Insulin receptor / Knockout mice / Transgenic mice / Insulin resistance / Sialidase / Ganglioside / Diabetes / タンスジェニックマウス / トラスジェニックマウス / neurodegeneration / knockout / lung cancer / melanoma / nervous system / glycosyltransferase / acidic glycolipids / シグナル / GEM / ミクロドメイン / ラフト / 相同組換え / GM3 / 神経変性 / ノックアウト / 肺癌 / メラノーマ / 神経 / 酸性糖脂質 / 癌血清診断 / 癌糖鎖特異的モノクロン抗体 / 癌遺伝子導入糖鎖変化 / 細胞表面糖鎖 / 細胞膜 / シグナル伝達 / 細胞内輸送 / 神経突起 / 大腸がん / Sialic acid(シアル酸) / Sialidase(シアリダーゼ) / T細胞受容体 / Gal転移酵素 / 癌細胞 / シアル酸転移酵素 / ベイシジン / GnT-III / 糖タンパク質 / ミドカイン / シアリルルイスX / α1-6フコシルトランスフェラーゼ / 細胞導入 / 糖鎖遺伝子 / プロティンホスファターゼ / Gタンパク / グルタチオンS-トランスフェラーゼ / マーカー酵素 / 血清酵素 / 蛋白キナ-ゼ / 糖脂質硫酸化酵素 / 遺伝子調節 / mRNA / cDNAクロ-ニング / 糖鎖合成酵素 / 転写調節 / がんマ-カ- / がん遺伝子 / CDNAクロ-ニング / 遺伝子発現 / cDNAクローニング Less
  • Research Projects

    (23 results)
  • Research Products

    (106 results)
  • Co-Researchers

    (39 People)
  •  シアリダーゼによる神経機能の制御Principal Investigator

    • Principal Investigator
      宮城 妙子
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku Pharmaceutical University
  •  Regulatory mechanism for intracellar traficking of the membrane-bound NEU3 sialidase

    • Principal Investigator
      YAMAGUCHI Kazunori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Miyagi Prefectural Hospital Organization Miyagi Cancer Center
  •  Pathogenesis of cancer and diabetes caused by aberrant expression of sialidasePrincipal Investigator

    • Principal Investigator
      MIYAGI Taeko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Tohoku Pharmaceutical University
  •  Molecular mechanism of regulation of cancer cell apoptosis by plasma membrane-associated sialidasePrincipal Investigator

    • Principal Investigator
      MIYAGI Taeko
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      宮城県立がんセンター研究所
      Miyagi Cancer Center Research Institute
  •  ムチン糖鎖を水解するシアリダーゼによる癌形質制御の分子機構Principal Investigator

    • Principal Investigator
      宮城 妙子
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Miyagi Cancer Center Research Institute
  •  形質膜シアリダーゼによるがん細胞のアポトーシス制御機構Principal Investigator

    • Principal Investigator
      宮城 妙子
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Miyagi Cancer Center Research Institute
  •  がんで異常亢進するシアリダーゼ遺伝子ノックダウンによるアポトーシス誘導機構Principal Investigator

    • Principal Investigator
      宮城 妙子
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Miyagi Cancer Center Research Institute
  •  Malignant alteration and its significance of a novel sialidase hydrolyzing mucinsPrincipal Investigator

    • Principal Investigator
      MIYAGI Taeko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Miyagi Cancer Center Research Institute
  •  Elucidation of abnormality of plasma membrane microdomain in type 2 diabetes mellitus

    • Principal Investigator
      SUZUKI Susumu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Tohoku University
  •  Microdomain abnormalities due to aberrant glycolipids

    • Principal Investigator
      FURUKAWA Koichi
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  The role of plasma membrane type sialidase gene Neu3 on the pathogenesis of type 2 diabetes mellitusin Japanese.

    • Principal Investigator
      SUZUKI Susumu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Tohoku University
  •  シアリダーゼ遺伝子による細胞リモデリング

    • Principal Investigator
      斎藤 誠一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  シアリダーゼ遺伝子による細胞リモデリングとその臨床応用

    • Principal Investigator
      斉藤 誠一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  シアリダーゼ遺伝子による細胞リモデリングとその臨床応用

    • Principal Investigator
      斎藤 誠一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  糖鎖遺伝子の特異性

    • Principal Investigator
      谷口 直之
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  肝発癌過程のマーカー酵素の特異的発現機構と機能の解明

    • Principal Investigator
      遠藤 英也
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tottori University
  •  ガングリオシドのみを水解する形質膜シアリダーゼの構造と機能の研究Principal Investigator

    • Principal Investigator
      宮城 妙子
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Tohoku University
  •  癌における糖鎖合成酵素の遺伝子発現と臨床応用

    • Principal Investigator
      牧田 章
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  肝発癌過程のマ-カ-酵素の特異的発現機構と機能の解明

    • Principal Investigator
      佐藤 清美
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hirosaki University
  •  癌における糖鎖合成酵素の遺伝子発現と臨床応用

    • Principal Investigator
      牧田 章
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  肝発癌過程のマ-カ-酵素の特異的発現機構と機能の解明

    • Principal Investigator
      佐藤 清美
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hirosaki University
  •  癌における糖鎖合成酵素の遺伝子発現と臨床応用

    • Principal Investigator
      牧田 章
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  癌の細胞膜糖鎖変化の機構と応用に関する研究

    • Principal Investigator
      牧田 章
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] Mammalian sialidase and tumor development (in Sugar Chains Eds Suzuki T., Ohtsubo K., Taniguchi N.)2015

    • Author(s)
      Miyagi T, Takahashi K, Shiozaki K, Yamaguchi K.
    • Total Pages
      16
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-24570142
  • [Book] Topics in Current Chemistry : Sialoglyco -Biology and -Chemistry2013

    • Author(s)
      Monti, E., Miyagi T
    • Total Pages
      19
    • Publisher
      Structure and function of mammalian sialidases
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Book] 第3の生命鎖、糖鎖の謎が今、解る(古川鋼一編, 糖鎖異常が招くがんの危険な性質-特にシアリダーゼ異常に着目して)2009

    • Author(s)
      宮城妙子
    • Publisher
      クバプロ
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Book] Experimental Glycoscience. Glycobiology.(Edited by Taniguchi, N., Suzuki, A. and Ito, Y., Aberrant expression of sialidase in cancer and diabetes.)2008

    • Author(s)
      Miyagi, T.
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Book] Glycobiology.(Edited by Taniguchi, N., Suzuki, A. and Ito, Y., Sialidase gene In Experimental Glycoscience.)2008

    • Author(s)
      Miyagi, T.
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Book] Biochemistry of Glycans2007

    • Author(s)
      Miyagi, T., Yamaguchi, K.
    • Total Pages
      20
    • Publisher
      Elsevier BV Amsterdam
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Book] Biochemistry of Glycans2007

    • Author(s)
      Miyagi, T., Yamaguchi, K.
    • Total Pages
      20
    • Publisher
      Elsevier BV Amsterdam
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Book] Biochemistry of Glycans2007

    • Author(s)
      Miyagi, T., Yamaguchi, K.
    • Total Pages
      20
    • Publisher
      Elsevier BV Amsterdam
    • Data Source
      KAKENHI-PROJECT-18013051
  • [Book] Biochemistry of Glycans2007

    • Author(s)
      Miyagi, T._and Yamaguchi, K.
    • Total Pages
      20
    • Publisher
      Elsevier BV Amsterdam
    • Data Source
      KAKENHI-PROJECT-18013051
  • [Book] Altered expression of sialidases in human cancer. Proceedings of the 9th ISCSM

    • Author(s)
      Miyagi T., Takahashi K., Moriya S., Hata K., Wada T. Yamaguchi K., Shiozaki K
    • Publisher
      Springer Publishers(in press)
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Book] Structure and function of mammalian sialidases. in Topics in Current Chemistry : Sialoglyco-Biology and-Chemistry

    • Author(s)
      Monti, E. and Miyagi, T
    • Publisher
      Springer(in press)
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Phosphatidic acid-mediated activation and translocation to the cell surface of sialidase NEU3, promoting signaling for cell migration.2015

    • Author(s)
      Shiozaki K, Takahashi K, Hosono M, Yamaguchi K, Hata K, Shiozaki M, Bassi R, Prinetti A, Sonnino S, Nitta K, Miyagi T.
    • Journal Title

      FASEB J

      Volume: 29 Issue: 5 Pages: 2099-2111

    • DOI

      10.1096/fj.14-262543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-25290047
  • [Journal Article] Plasma membrane-associated sialidase confers cancer initiation, promotion and progression.2015

    • Author(s)
      Miyagi T, Takahashi K, Shiozaki K, Yamaguchi K, Hosono M
    • Journal Title

      Adv Exp Med Biol.

      Volume: 842 Pages: 139-145

    • DOI

      10.1007/978-3-319-11280-0_9

    • ISBN
      9783319112794, 9783319112800
    • Data Source
      KAKENHI-PROJECT-24570142
  • [Journal Article] Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serum.2015

    • Author(s)
      Hata K, Tochigi T, Sato I, Kawamura S, Shiozaki K, Wada T, Takahashi K, Moriya S, Yamaguchi K, Hosono M, Miyagi T.
    • Journal Title

      Cancer Sci

      Volume: 106 Issue: 4 Pages: 383-389

    • DOI

      10.1111/cas.12627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-25430163
  • [Journal Article] Sialidase NEU3 contributes neoplastic potential on colon cancer cells as a key modulator of gangliosides by regulating Wnt signaling.2015

    • Author(s)
      Takahashi K, Hosono M, Sato I, Hata K, Wada T, Yamaguchi K, Nitta K, Shima H, Miyagi T.
    • Journal Title

      Int J Cancer

      Volume: published online Issue: 7 Pages: 00-00

    • DOI

      10.1002/ijc.29527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-26430130, KAKENHI-PROJECT-25430163
  • [Journal Article] がんとシアル酸2014

    • Author(s)
      宮城妙子
    • Journal Title

      実験医学

      Volume: 31 Pages: 1545-1552

    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Journal Article] がんのシアリダーゼ異常2014

    • Author(s)
      宮城妙子
    • Journal Title

      化学と生物

      Volume: 52 Pages: 76-82

    • NAID

      130004808942

    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Journal Article] Possible association of Neu2 with plasma membrane fraction from mouse thymus exhibited sialidase activity with fetuin at pH 7.0 but not at pH 4.52014

    • Author(s)
      Kijimoto‐Ochiai S, Doi1 S, Fujii N, Go S, Kabayama K, Moriya S, Miyagi T and Koda T
    • Journal Title

      Microbiol Immunol

      Volume: 57 Issue: 8 Pages: 569-582

    • DOI

      10.1111/1348-0421.12076

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Journal Article] Molecular cloning and biochemical characterization of two novel Neu3 sialidases, neu3a and neu3b, from medaka (Oryzias latipes)2013

    • Author(s)
      Shiozaki K, Takeshita K, Ikeda M, Ikeda A, Harasaki Y, Komatsu M, Yamada S, Yamaguchi K, Miyagi T
    • Journal Title

      Biochimie

      Volume: 95 Issue: 2 Pages: 280-289

    • DOI

      10.1016/j.biochi.2012.09.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592471, KAKENHI-PUBLICLY-24110514, KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-24580304, KAKENHI-PROJECT-24780204
  • [Journal Article] シアリダーゼによる細胞接着の制御2013

    • Author(s)
      高橋耕太、塩崎一弘、宮城妙子
    • Journal Title

      生体の科学

      Volume: 64 Pages: 273-278

    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Journal Article] Plasma membraneassociated sialidase(NEU3) regulates progression of prostate cancer to androgen-independent growth through modulation of androgen receptor signaling2012

    • Author(s)
      Kawamura, S., Sato, I., Wada, T., Yamaguchi, K., Li, Y., Li, D., Zhao, X., Ueno, S., Aoki, H., Tochigi, T., Kuwahara, M. Kitagawa, T., Takahashi, K., Moriya, S., Miyagi, T
    • Journal Title

      Cell Death Differ

      Volume: 19 Pages: 170-179

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Sialidase significance for cancer progression,2012

    • Author(s)
      Taeko Miyagi et al
    • Journal Title

      Glycoconjugate J.

      Volume: 29 Issue: 8-9 Pages: 567-577

    • DOI

      10.1007/s10719-012-9394-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Journal Article] Mammalian sialidases : physiological and pathological roles in cellular functions2012

    • Author(s)
      Miyagi, T., et al
    • Journal Title

      Glycobiology

      Volume: 22 Issue: 7 Pages: 880-896

    • DOI

      10.1093/glycob/cws057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570122, KAKENHI-PROJECT-23592471, KAKENHI-PUBLICLY-24110514
  • [Journal Article] Altered expression of sialidases in human cancer2012

    • Author(s)
      Miyagi T, Takahashi K, Moriya S, Hata K, Yamamoto K, Wada T, Yamaguchi K, Shiozaki K
    • Journal Title

      Adv Exp Med Biol

      Volume: 749 Pages: 257-267

    • DOI

      10.1007/978-1-4614-3381-1_17

    • ISBN
      9781461433804, 9781461433811
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592471, KAKENHI-PROJECT-24570142, KAKENHI-PUBLICLY-24110514
  • [Journal Article] Mammalian sialidases : physiological and pathological roles in cellular functions2012

    • Author(s)
      Miyagi, T., Yamaguchi, K
    • Journal Title

      Glycobiology

      Volume: 22 Pages: 880-896

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides2011

    • Author(s)
      Miyata, M., Kambe, M., Tajima, O., Moriya, S., Sawaki, H., Hotta, H., Kondo, Y., Narimatsu, H., Miyagi, T., Furukawa, K., Furukawa, K
    • Journal Title

      Cancer Sci

      Volume: 102 Pages: 2139-2149

    • NAID

      10030245717

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU42011

    • Author(s)
      Shiozaki, K., Yamaguchi, K., Takahashi, K., MoriyaS., Miyagi, T
    • Journal Title

      J. Biol Chem

      Volume: 286 Pages: 21052-21061

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] A crucial role of sialidase Neu1 in hyaluronan receptor function of CD44 in T helper type 2-mediated airway inflammation of murine acute asthmatic model2010

    • Author(s)
      Katoh S, Maeda S, Fukuoka H, Wada T, Moriya S, Mori A, Yamaguchi K, Senda S, Miyagi T
    • Journal Title

      Clin Exp Immunol

      Volume: 161 Pages: 233-241

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Regulation of plasma membrane-associated sialidase NEU3 gene by Sp1/Sp3 transcription factors2010

    • Author(s)
      Yamaguchi, K., Koseki, K., Shiozaki, M., Shimada, Y., Wada, T., Miyagi, T
    • Journal Title

      Biochem, J

      Volume: 430 Pages: 107-117

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] A crucial role of sialidase Neu1 in hyaluronan receptor function of CD44 in T helper type 2- mediated airway inflammation of murine acute asthmatic model2010

    • Author(s)
      Katoh S, Maeda S, Fukuoka H, Wada T, Moriya S, Mori A, Yamaguchi K, Senda S, Miyagi T.
    • Journal Title

      Clin Exp Immunol (in press)

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Mammalian sialidases and their functions2010

    • Author(s)
      Miyagi T
    • Journal Title

      Trends In Clycoscien and Glycotechnology

      Volume: 22 Pages: 162-172

    • NAID

      10027508537

    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Regulation of plasma membrane-associated sialidase NEU3 gene by Sp1/Sp3 transcription factors2010

    • Author(s)
      Yamaguchi, K., Koseki, K., Shiozaki, M., Shimada, Y., Wada, T., Miyagi, T.
    • Journal Title

      Biochem, J. (in press)

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Mammalian sialidases and their functions.2010

    • Author(s)
      Miyagi T.
    • Journal Title

      Trends Glycosci.Glyc

      Volume: 22 Pages: 162-172

    • NAID

      10027508537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Journal Article] Synthesis of all possible isomers corresponding to the proposed structure of montanacin e, and their antitumor activity2009

    • Author(s)
      Takahashi S, Takahashi R, Hongo Y, Koshino H, Yamaguchi K, Miyagi T
    • Journal Title

      J Org Chem. 74

      Pages: 6382-6385

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Human sialidase inhibitors: design, synthesis, and biological evaluation of 4-acetamido-5-acylamido- 2-fluoro benzoic acids2009

    • Author(s)
      Magesh S, Savita V, Moriya S, Suzuki T, Miyagi T, Ishida H, Kiso M.
    • Journal Title

      Bioorg Med Chem. 17

      Pages: 4595-603

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Developmental change of sialidase NEU4 expression in murine brain and its involvement in the regulation of neuronal cell differentiation2009

    • Author(s)
      Shiozaki K, Koseki K, Yamaguchi K, Shiozaki M, Narimatsu H, Miyagi T.
    • Journal Title

      J. Biol. Chem. 284

      Pages: 21157-21164

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Plasma membrane -associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice2009

    • Author(s)
      Shiozaki, K., Yamaguchi, K., Sato, I., Miyagi, T.
    • Journal Title

      Cancer Sci. 100

      Pages: 588-594

    • NAID

      10025143974

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta 42009

    • Author(s)
      Uemura, T, Shiozaki, K., Yamaguchi, K., Miyazaki, S., Satomi, S., Kato, K., Sakuraba, H., Miyagi, T.
    • Journal Title

      Oncogene 28

      Pages: 1218-1229

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous gd1a2009

    • Author(s)
      Wang J, Wu G, Miyagi T, Lu ZH, Ledeen RW.
    • Journal Title

      J Neurochem 111

      Pages: 547-554

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] A strategy for constructing C-sialosides based on Ireland-Claisen rearrangement and its application for synthesis of CF2-linked ganglioside GM4 analogue2009

    • Author(s)
      Sodeoka, M., Hirai, G., Watanabe, T., Miyagi, T.
    • Journal Title

      Pure Applied Chem. 81

      Pages: 205-215

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] シアリダーゼによる細胞機能の制御とその異常2008

    • Author(s)
      宮城妙子
    • Journal Title

      生化学 80

      Pages: 13-23

    • NAID

      10021190601

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases. Antimicrob2008

    • Author(s)
      Hata, K., Koseki, K., Yamaguchi, K., Moriya, S., Suzuki, Y., Yingsakmongkon, S., Hirai, G., Sodeoka, M., von Itzstein, M., Miyagi, T.
    • Journal Title

      Agents Chemother. 25

      Pages: 3484-3491

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Roles of plasma membrane-associated sialidase NEU3 in human cancers.2008

    • Author(s)
      Miyagi, T., et. al.
    • Journal Title

      Biochim. Biophys. Acta 1780

      Pages: 532-537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013051
  • [Journal Article] Human sialidase as a cancer marker2008

    • Author(s)
      Miyagi, T., Wada T., Yamaguchi, K., Shiozaki, K., Sato, I., Yamanami, H., Kakugawa, Y., Fujiya, T.
    • Journal Title

      Proteomics 8

      Pages: 3303-3311

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Aberrant expression of sialidase and cancer progression2008

    • Author(s)
      Miyagi, T.
    • Journal Title

      Proc Jpn Acad Ser B 84

      Pages: 407-418

    • NAID

      130000093946

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Plasma membane-associated sialidase as a crucial regulator of transmenbrane signaling2008

    • Author(s)
      Miyagi, T., et al.
    • Journal Title

      J Biochem 144

      Pages: 279-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] シアリダーゼによる細胞機能の制御とその異常2008

    • Author(s)
      宮城妙子
    • Journal Title

      生化学 80

      Pages: 13-23

    • NAID

      10021190601

    • Data Source
      KAKENHI-PROJECT-18013051
  • [Journal Article] Human sialidase as a cancer marker.2008

    • Author(s)
      Miyagi, T., et. al.
    • Journal Title

      Proteomics (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013051
  • [Journal Article] Human sialidase as a cancer marker.2008

    • Author(s)
      Miyagi, T., et al.
    • Journal Title

      Proteomics 8

      Pages: 3303-3311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Synthesis of CH2-Linked a(2, 3)Sialylgalactose Analogue: on the stereoselectivity of the Key Ireland-Claisen rearrangement2008

    • Author(s)
      Watanabe, T., Hirai, G., Kato, M., Hashizume, D., Miyagi, T., Sodeoka, M.
    • Journal Title

      Org. Lett. 10

      Pages: 4167-4170

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] シアリダーゼによる細胞機能の制御とその異常2008

    • Author(s)
      宮城 妙子
    • Journal Title

      生化学 80

      Pages: 13-23

    • NAID

      10021190601

    • Data Source
      KAKENHI-PROJECT-19659104
  • [Journal Article] Human sialidase as a cancer marker2008

    • Author(s)
      Miyagi, T., et. al.
    • Journal Title

      Proteomics (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Journal Article] Aberrant expression of sialidase and cancer progression2008

    • Author(s)
      Miyagi T.
    • Journal Title

      Proc Jpn Acad 84

      Pages: 407-418

    • NAID

      130000093946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Journal Article] Plasma membane-associated sialidase as a crucial regulator of transmenbrane signaling2008

    • Author(s)
      Miyagi, T., et al.
    • Journal Title

      J Biochem 144

      Pages: 279-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Journal Article] Roles of plasma membrane-associated sialidase NEU3 in human cancers2008

    • Author(s)
      Miyagi, T., et. al.
    • Journal Title

      Biochim. Biophys. Acta 1780

      Pages: 532-537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Journal Article] Minireview, Plasma membrane - associated sialidase as a crucial regulator of transmenbrane signaling2008

    • Author(s)
      Miyagi, T., Wada, T., Yamaguchi, K., Hata, H., Shiozaki, K.
    • Journal Title

      J. Biochem 144

      Pages: 79-285

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Roles of plasma membrane-associated sialidase NEU3 in human cancers2008

    • Author(s)
      Miyagi, T. Wada, T., Yamaguchi, K.
    • Journal Title

      Biochim. Biophys. Acta 1780

      Pages: 532-537

    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Human sialidase as a cancer marker2008

    • Author(s)
      Miyagi, T., et al.
    • Journal Title

      Proteomics 8

      Pages: 3303-3311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Journal Article] Aberrant expression of sialidase and cancer progression2008

    • Author(s)
      Miyagi T.
    • Journal Title

      Proc Jpn Acad 84

      Pages: 407-418

    • NAID

      130000093946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Journal Article] Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites2007

    • Author(s)
      Hasagawa, T., Sugeno, N., Takeda, A., Matsuzaki-Kobayashi, M., Kikuchi, A., Furukawa, K., Miyagi, T., Itoyama, Y.
    • Journal Title

      FEBS Lett. 581

      Pages: 406-412

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] A crucial role of plasma membrane-associated sialidase (NEU3) in the survival of human cancer cells.2007

    • Author(s)
      Wada, T., Hata, K., Yamaguchi, K., Shiozaki, K., Koseki, K., Moriya, S., Miyagi, T.
    • Journal Title

      Oncogene 26

      Pages: 2483-2490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes the interleukin-6-induced apoptosis suppression and cell motility.2006

    • Author(s)
      Ueno, S., Saito, S., Wada, T., Yamaguchi, K., Satoh, M., Arai, Y., Miyagi, T.
    • Journal Title

      J.Biol.Chem. 281

      Pages: 7756-7764

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Epidermal growth factor-induced mobilization of a ganglioside-specific sialidase (NEU3) to membrane ruffles.2006

    • Author(s)
      Yamaguchi K, Hata K, Wada T, Moriya S, Miyagi T.
    • Journal Title

      Biochem.Biophys Res Commun. 346

      Pages: 484-490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2 : Hints for the design of selective NEU3 inhibitors.2006

    • Author(s)
      Magesha, S., Suzukib, T., Miyagi, T., Ishidaa, H., Kiso, M.
    • Journal Title

      J.Mol.Graph.Model. 25

      Pages: 196-207

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Plasma membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin-and fibronectin-derived signaling.2006

    • Author(s)
      Kato, K., Shiga, K., Yamaguchi, K., Hata, K., Kobayashi, T., Miyazaki, K., Saijo, S., Miyagi, T.
    • Journal Title

      Biochem.J. 394

      Pages: 647-656

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Down-regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers.2006

    • Author(s)
      Yamanami, T., Shiozaki, K., Wada, T., Yamaguchi, K., Uemura, T., Kakugawa, Y., Fujiya T., Miyagi, T.
    • Journal Title

      Cancer Sci. 98

      Pages: 299-307

    • NAID

      10019481340

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Evidence for Mitochondrial Localization of a Novel Human Sialidase (NEU4).2005

    • Author(s)
      Yamaguchi, T., Hata, K., Koseki, K., Shiozaki, K., Akita, H., Wada, T., Moriya, S., Miyagi, T.
    • Journal Title

      Biochem.J. 390

      Pages: 85-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Asymmetric membrane ganglioside sialidase activity specifies axonal fate.2005

    • Author(s)
      Da Silva JS, Hasegawa T, Miyagi T, et al.
    • Journal Title

      Nature Neuroscience 8・5

      Pages: 606-615

    • Data Source
      KAKENHI-PROJECT-16390259
  • [Journal Article] A symmetric membrane ganglioside sialidase activity specifies axonal fate.2005

    • Author(s)
      Da Silva, J.S., Hasegawa, T., Miyagi, T., Dotti.C.J., Avad-Rodriguez, J.
    • Journal Title

      Nat.Neurosci. 8

      Pages: 606-615

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Journal Article] Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2 : Hints for the design of selective NEU3 inhibitors.

    • Author(s)
      Magesh S, Suzuki T, Miyagi T et al.
    • Journal Title

      J Mol Graph Model (印刷中)

    • Data Source
      KAKENHI-PROJECT-16390259
  • [Journal Article] Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice.

    • Author(s)
      Yoshizumi, S., Suzuki, S., Hirai, M., Hinokio, Y., Yamada, T., Yamada, T., Tsunoda, U., Aburatani, H., Yamaguchi, K., Miyagi, T., Oka, Y.
    • Journal Title

      Metabolism 56

      Pages: 420-429

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390119
  • [Patent] がんまたは糖尿病治療のための医薬組成物2005

    • Inventor(s)
      宮城 妙子, 和田 正, 山口 壹範
    • Industrial Property Rights Holder
      宮城県
    • Filing Date
      2005-11-15
    • Data Source
      KAKENHI-PROJECT-17014084
  • [Presentation] Sialidase in cancer progression2012

    • Author(s)
      Taeko Miyagi
    • Organizer
      Sialo-Glyco 2012
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2012-09-10
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] シアリダーゼ異常による大腸がんの進展機構と治療への応用2012

    • Author(s)
      宮城妙子ら
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島
    • Year and Date
      2012-09-17
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] 担がん患者血清におけるシアリダーゼ活性の同定と診断への応用.2012

    • Author(s)
      宮城妙子ら
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] シアリダーゼによる癌進展機構とその治療への応用2012

    • Author(s)
      宮城妙子
    • Organizer
      第21回、日本がん転移学会学術総会
    • Place of Presentation
      広島
    • Year and Date
      2012-07-13
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] シアリダーゼ異常による癌進展機構2012

    • Author(s)
      宮城妙子
    • Organizer
      戦略的研究基盤形成支援事業シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2012-11-03
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] Aberrant expression of sialidase and cancer progression2011

    • Author(s)
      Miyagi, T.
    • Organizer
      US-JAPAN Conference : Inflammation, Diabetes and Cancer
    • Place of Presentation
      City Of Hope, Duarte, CA, USA(招待講演)
    • Year and Date
      2011-08-04
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Distinct functional roles between ganglioside sialidases Neu3 and Neu42011

    • Author(s)
      Miyagi, T., Yamaguchi, K., Shiozaki, K., Takahashi, K., Wada, T., Hata, K., Moriya, S., Yamamoto, K
    • Organizer
      The 31st Naito Conference : Glycan Expression and Regulation[II]: Metabolites, Stress Response, Microdomains, and Beyond
    • Place of Presentation
      Sapporo, Japan
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] がんで過剰発現する形質膜シアリダーゼNEU3の悪性化進展機構2011

    • Author(s)
      宮城妙子, ら
    • Organizer
      日本糖質学会
    • Place of Presentation
      長岡(長岡リリックホール)
    • Year and Date
      2011-07-12
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Aberrant expression of sialidase and cancer progression2011

    • Author(s)
      Miyagi, T
    • Organizer
      US-JAPA Conference : Inflammation, Diabetes, And Cancer
    • Place of Presentation
      City of Hope, Duarte CA, USA
    • Year and Date
      2011-08-04
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Altered expression of sialidases in human cancer2011

    • Author(s)
      Miyagi T., et al
    • Organizer
      IXth International Symposium (IXth ISCSM, 2011)
    • Place of Presentation
      Trivandrum, India
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Distinct functional roles between ganglioside sialidases Neu3 and Neu42011

    • Author(s)
      Miyagi, T., et al
    • Organizer
      The 31st Naito Conference : Glycan Expression and Regulation [II] : Metabolites, Stress Response, Microdomains, and Beyond
    • Place of Presentation
      Chateraise Gateaux Kingdom, Sapporo, Japan(招待講演)
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] がん幹細胞様形質発現におけるシアリダーゼNEU3の役割2011

    • Author(s)
      宮城妙子
    • Organizer
      日本がん転移学会
    • Place of Presentation
      浜松(アクトシティ浜松)
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Altered expression of sialidases in human cancer2011

    • Author(s)
      Miyagi, T., Takahashi, K., Moriya, S., Hata, K., Wada, T., Yamaguchi, K., Shiozaki, K
    • Organizer
      IXth International Symposium(IXth ISCSM, 2011) on "Biochemical Roles of Eukaryotic Cell Surface Macromolecules"
    • Place of Presentation
      Trivandrum, India
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Sialidase NEU4 attenuates E-selectin derived signaling in colon cancer cells2010

    • Author(s)
      Miyagi T., et al
    • Organizer
      SIALOGLYCO 2010
    • Place of Presentation
      Potsdam, Germany.
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PROJECT-22659082
  • [Presentation] Role of sialidase NEU3 in prostate cancer progression and its potential utility as a novel; therapeutic target2009

    • Author(s)
      Miyagi T.
    • Organizer
      Clinical and translational Research on cancer: Glycomics Applications
    • Place of Presentation
      Toba, Mie
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Sialidase Neu4 contributes to attenuation of E-selectin-derived signaling in colon cancer cells.2009

    • Author(s)
      Miyagi T.
    • Organizer
      Tohoku carbohydrate minisymposium
    • Place of Presentation
      Fukusima
    • Year and Date
      2009-03-22
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Role of sialidase NEU3 in prostate cancer progression and its potential utility as a novel therapeutic target2009

    • Author(s)
      Miyagi T.
    • Organizer
      Clinical and translational Research on cancer : Glycomics applications
    • Place of Presentation
      Toba, Mie, Japan
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Role of sialidase NEU3 in prostate cancer progression and its potential utility as a novel; therapeutic target.Clinical and translational Research on cancer:2009

    • Author(s)
      Miyagi T.
    • Organizer
      Glycomics applications.
    • Place of Presentation
      Toba, Mie
    • Year and Date
      2009-03-25
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Sialidase Neu4 contributes to attenuation of E-selectin-derived signaling in colon cancer cells2009

    • Author(s)
      Miyagi T.
    • Organizer
      Tohoku carbohydrate minisymposium
    • Place of Presentation
      Fukushima
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Crucial roles of plasma membrane-associated sialidase in human cancer2008

    • Author(s)
      Miyagi T., et al.
    • Organizer
      13^<th> World Congress on advances in Oncology
    • Place of Presentation
      Crete, Greece
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Presentation] Crucial roles of plasma membrane-associated sialidase in human cancer2008

    • Author(s)
      Miyagi, T., Wada, T., Yamaguchi, K, Hata, K., Shiozaki, K.
    • Organizer
      13th World Congress on advances in Oncology
    • Place of Presentation
      Crete, Greece
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Sialidase research targeted to cancer diagnosis and therapy2008

    • Author(s)
      Miyagi, T., et al.
    • Organizer
      第67回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Crucial roles of plasma membrane-associated sialidase in human cancer2008

    • Author(s)
      Miyagi T., et al.
    • Organizer
      13^<th> World Congress on advances in Oncology
    • Place of Presentation
      Crete, Greece
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-20013047
  • [Presentation] Plasma membrane-associated sialidase as a crucial regulator for transmembrane signaling in human cancer2007

    • Author(s)
      Miyagi, T., et. al.
    • Organizer
      The 27th Sapporo Cancer Seminar International Symposium
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-19659104
  • [Presentation] Plasma membrane-associated sialidase as a crucial regulator for transmembrane signaling in human cancer,2007

    • Author(s)
      Miyagi, T., et. al.
    • Organizer
      The 27th Sapporo Cancer Seminar International Symposium,
    • Place of Presentation
      Sapporo,
    • Data Source
      KAKENHI-PROJECT-18013051
  • [Presentation] シアリダーゼNEU3によるWntシグナルを介した大腸がん細胞の造腫瘍能制

    • Author(s)
      高橋耕太, 細野雅祐, 和田正,山口壹範, 仁田一雄, 宮城妙子
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] シアリダーゼNEU3によるWntシグナルを介した大腸がん細胞の造腫瘍能制御

    • Author(s)
      高橋耕太、細野雅祐、秦敬子、和田正、山口壹範、仁田一雄、宮城妙子
    • Organizer
      第79回日本生化学会東北支部会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] Sialidase confers neoplastic potential by regulating Wnt signaling.

    • Author(s)
      Miyagi T, Takahashi K, Hosono M, Hata K, Wada T, Moriya S, Yamaguchi K, Nitta K.
    • Organizer
      ISCSM 10 “Biochemical Roles of Eukaryotic Cell Surface Macromolecules”
    • Place of Presentation
      Kolkata, India
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] シアリダーゼはがんの発がん過程と進展に関与する

    • Author(s)
      宮城妙子、高橋耕太、細野雅祐、塩崎一弘、山口壹範
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24570142
  • [Presentation] シアリダーゼNEU3によるがん化能の制御

    • Author(s)
      宮城妙子、高橋耕太、細野雅祐、和田正、森谷節子、秦敬子、山本晃司、山口壹範、仁田一雄
    • Organizer
      第32回日本糖質学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] ヒト血清におけるシアリダーゼ活性およびその阻害活性の同定

    • Author(s)
      秦 敬子、森谷節子、細野雅祐、和田 正、高橋耕太、塩崎一弘、仁田一雄、宮城妙子
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] シアリダーゼ異常による大腸がんの進展機構と治療への応用

    • Author(s)
      宮城妙子
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島市民文化ホール
    • Data Source
      KAKENHI-PROJECT-24570142
  • [Presentation] Roles of sialidase in cancer initiation and progression.

    • Author(s)
      Miyagi T,Takahashi K, Hosono M, Yamamoto K, Nitta K.
    • Organizer
      XXIIth International Symposium on Glycoconjugates,
    • Place of Presentation
      Dalian, China,
    • Data Source
      KAKENHI-PUBLICLY-24110514
  • [Presentation] がん化におけるシアリダーゼの役割

    • Author(s)
      宮城妙子
    • Organizer
      第11回日本糖鎖科学コンソーシアムシンポジウム
    • Place of Presentation
      仙台
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24110514
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