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MORISHIMA Isao  森島 績

ORCIDConnect your ORCID iD *help
… Alternative Names

森島 積  モリシマ イサオ

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Researcher Number 50026093
Affiliation (based on the past Project Information) *help 1995 – 2003: 京都大学, 工学研究科, 教授
1989 – 2000: 京都大学, 工学部, 教授
1999: 京都大学, 大学院・工学研究所, 教授
1999: 京都大学, 大学院・工学研究科, 教授
1996: Kyoto University, Engineering, Professor, 大学院・工学研究科, 教授 … More
1996: 京都大学大学院, 工学研究科, 教授
1994: 京都大学, 大学院・工学研究科, 教授
1994: 京都大学, 大学院・工学部, 教授
1994: Kyoto University, Faculty of Engineering.Professor, 工学研究科, 教授
1990: Graduate School of Engineering, Kyoto University, 工学部, 助教授
1986 – 1988: 京都大学, 工学部, 助教授
1986: 京大, 工学部, 助教授 Less
Review Section/Research Field
Principal Investigator
広領域 / 物理化学一般 / 工業物理化学 / Structural biochemistry / Chemistry / Inorganic chemistry / Biophysics
Except Principal Investigator
Biophysics / Inorganic chemistry / 広領域 … More / 無機・錯塩・放射化学 / 無機工業化学 / Physical chemistry / 代謝生物化学 Less
Keywords
Principal Investigator
ヘム蛋白質 / 活性化体積 / ヘムタンパク質 / 高圧NMR / ミオグロビン / モジュール / チトクロムP450 / 亜硫酸還元酵素 / フェレドキシン / ペルオキシターゼ … More / Molybdenum and Tungusten-substituted Hemoproteins / Metal-substituted Hemoproteins / 分子工学 / 機能制御 / グリーンヘム蛋白 / モリブデンヘム / ルテニウムヘム / 金属置換ヘム / クロクン含有ヘムタンパク質 / グリーンヘムタンパク質 / ルテンウム置換ヘモグロビン / ニッケル置換ミオグロビン / タングステン置換ヘムタンパク質 / モリブデン / 金属置換ヘムタンパク質 / Electron Transfer in Proteins / Hemoproteins / High Presure Flash Photolysis / High Pressure Muiti-Nuclear NMR / 蛋白質内電子伝達反応 / 高圧下フラッシュホトリシス / 高圧多次元NMR / Globin / Exon Shaffling / Module / エクソンジャフリング / グロビン蛋白質 / エクソンシャフリング / Cytochrome P450 / Cytochrome c Oxidase / Oxgen Snsor Fix L / Nitrite Reductase / Ferredoxin / Peroxidase / チトクロム酸化酵素 / 酸素センサーFixL / 蛋白質内電子伝達 / 亜硝酸還元酵素 / CO Rebinding / Electron Transfer / Ligand Binding / Activation Volume / Laser Photolysis / High-Pressure Kinetics / Hemoglobin / Myoglobin / レ-ザ-フォトリシス / 電子伝達 / ヘモグロビン / 高圧下レーザーフラッシュフォトリシス / 高圧レーザーフォトリシス / 高圧分子分光法 / 高圧レ-ザ-フォトリシス / ND交換の圧力依存性 / NH / ヘム反転反応 / ヘム交換反応 / タンパク質分子設計 / ペプチドライゲーション / モジュールライゲーション / 酸素結合能 / カルシウム結合ループ / アロステリック蛋白質 / 分子設計 / 生物物理化学 / 酵素 / 生体分子 / 生物物理学 / 蛋白質工学 / 鉄オキソポルフィリンπカチオンラジカル / Compound 0 / Compound I / 西洋ワサビペルオキシターゼ / 高速混合装置 / 高圧レーザーフラッシュフォトリシス / 揺らぎ / 電子移動複合体 / チトクロムb5 / レーザーフラッシュフォトリシス / 亜鉛置換ミオグロビン / 電子移動 / モジュール置換 / 金属蛋白質 / 鉄5価ポルフィリン / 鉄-硫黄蛋白質 / チトクロムc3 / チトクロムc2 / P-450 / 軸配位子置換 / チトクロームC2の結晶構造 / 電子移動過程 / パルスラジオリシス / 鉄イオウ蛋白質のモデル錯体 / チトクロームC3のミクロ構造 / モジュール置換ヘモグロビン / チトクロームP450変異体 / チトクロームP450モデル / 電子伝達ヘム蛋白質 / 酸素添加反応 / 配位子結合反応 / アミノ酸置換蛋白質 / 光誘起電子移動 / 金属置換ミオグロビン … More
Except Principal Investigator
金属タンパク質 / 蛋白質 / 金属酵素 / 生体関連金属錯体 / 多重相互作用 / 生物無機化学 / Pー450_<14DM> / cytochrome d / heme / compound I / 人工変異タンパク質 / タンパク質 / Proteins / 分子認識 / プラチナ / 生体情報変換 / 生体エネルギー変換 / ダイナミックス / 立体構造予測 / グアニレートシクラーゼ / NO合成酵素 / 二酸化炭素固定 / 光合成系マンガン錯体 / 銅酵素 / 金属酵素モデル / Pー450_<aldo> / Pー450_<11β> / 部位特異的変異 / チトクロームPー450 / oxygen activation / cytochrome oxidase / cytochromes / heme proteins / gene control / biometals / Metallo-nuclic acid / Metallo-proteins / 生体無機化学 / 小分子活性化 / 生体情報伝達 / 生体エネルギー / 生体金属 / 金属核酸 / 分子生物学 / 構造生物学 / 生体分子科学 / 光合成 / 小分子の活性化 / 金属核酸錯体 / 金属タンパク / Molecular dynamics / Molecular evolution / Molecular spectroscopy / Artificial mutation / Myoglobin / Hemoglobin / Oxygen binding proteins / 分子動力学 / 分子進化 / 分子分光学 / 人工変異 / ミオグロビン / ヘモグロビン / 酸素結合蛋白質 / Module / Threading / principal variety of protein folds / Structural prediction / Structural comparison / Principle of architecture / Three-dimensional structure / Protein / 膜蛋白質 / 相同蛋白質 / タンパク質デザイン / モデリング / 構造分類 / リゾチウム / キメラタンパク / ファージディスプレイ / 膜タンパク質 / 立体構造比較 / スレッティング / モジュール / スレッディング / 立体構造基本型 / 構造予測 / 構造比較 / 構築原理 / 立体構造 / THERMOSTABILIZED ENZYME / MODULE SHUFFLING / FITNESS LANDSCAPE / ADAPTIVE WALK / SEQUENCE SPACE / IN VITRO EVOLUTION / EXPERIMENTAL EVOLUTION / EVOLUTIONARY MOLECULAR ENGINEERING / キメラ蛋白 / 耐熱静翼酵素 / エクソンシャフリング / 階層的分子進化 / 高分子工学 / ウイルス型対応づけ / 配列空間の適応歩行 / 耐熱化酵素 / モジュールシャクリング / 競争的共存 / 耐熱性酵素 / モジュールシャフリング / 適応度の地形 / 適応歩行 / 配列空間 / 試験管内分子進化 / 実験分子進化 / 進化分子工学 / cation radical / chlorin / 反応機構 / 酸素活性化 / 酵素モデル / 鉄クロリン錯体 / Compound I / Cytochrome d / カチオンラジカル / クロリン / Election transfer pathway / Oxygen carrier / Molecular recognition system / Metalloenzyme model / Biological reaction process / Multiple interaction / Biological metal complex / 人工変異ヘムタンパク質 / DNA塩基認識 / 国際シンポジウム / 電子移動反応系 / 酸素運搬体 / 分子認識系 / 生体内反応過程 / Protein dynamics / MO calculation / Spectroscopy / Biomachine / 時間分解分光学 / 生体分子分光学 / 量子生物学 / MO計算 / 分光学 / バイオマシン / 9 Protein Recognition / Protein Structure / Brain / Micromachine / Bioclectronics / Biocomputer / Biochip / Biosensor / マイクロマシン / バイオコンピュ-タ- / バイオエレクトロニクス / バイオチップ / バイオセンサ- / 高次構造 / アロマターゼ反応 / Pー450_<17α、lyase> / Pー450_<C21> / Pー450 / 銀 / 触媒作用 / 化学吸着 / 表面 / 機能性錯体 / 金属イオンの生理活性 / 生体系モデル錯体 / 配位環境 / 生体系金属イオン / 化学シフト / ダングリンボンド / 触媒理論 / 電子論 / 無機材料 / 遺伝子発現制御 / ペルオキシターゼ / チトクロム酸化酵素 / 安定性 / 折れたたみ / 立体構造安定性 / デザイン / 立体構造比較分類 / 一酸化窒素 / チトクロムP-450 / NO-ヘム / ケージ化合物 / 緩和時間測定 / NMR分光法 / 蛋白質の動的構造 / 蛋白質の構造 / 時間分割解析 / ラウエ法 / X線結晶構造解析 / ス-パ-オキシドアニオン / チトクロムPー450 / オキシゲナ-ゼ / チトクロムcオキシダ-ゼ / 酸素毒性 / 活性酸素 / 酸素の活性化 / 酸素 / ヘムタンパク質 / 反応速度制御 / 学際的共同研究 / 生体内反応の精密モデル化 / 時間分解分光法 / Pー450_<cam> / 副腎皮質ミトコンドリア / チトクロ-ムPー450 / Pー450cam / 副腎ミトコンドリア / Pー450aldo / P45011β / マデルングポテンシャル / 吸着 / ZnO / 電子状態 / 理論 / 酸化物触媒 / 半導体触媒 / 固体触媒作用 Less
  • Research Projects

    (36 results)
  • Co-Researchers

    (111 People)
  •  構造及び機能単位としてのモジュールを組み合わせた新規蛋白質の分子設計と創製Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Chemistry
    • Research Institution
      Kyoto University
  •  生体金属による小分子の活性化Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  蛋白質構造の「揺らぎ」による電子移動過程の制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Kyoto University
  •  金属酵素の不安定中間体を観測するための高速溶液混合実験システムの開発Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Inorganic chemistry
    • Research Institution
      Kyoto University
  •  Molecular Science on the Specific Roles of Metal Ions in Biological Functions.

    • Principal Investigator
      KITAGAWA Teizo
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  生体機能における金属イオンの特異的作用の分子科学

    • Principal Investigator
      北川 禎三
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Physical chemistry
    • Research Institution
      Okazaki National Research Institutes
  •  Protein structure, comparison, prediction, and design

    • Principal Investigator
      GO Nobuhiro, 野口 俊之
    • Project Period (FY)
      1995 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      KYOTO UNIVERSITY
      Nagoya University
  •  Molecular manipulation of oxygen binding proteins and new development of precise structure-function studies on them

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      Osaka University
  •  Structural Regulation Mechanism for Reactivity in MetalloproteinsPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      KYOTO UNIVERSITY
  •  Protein Engineering for New Functional Hemoproteins Based on Module SubstitutionPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      KYOTO UNIVERSITY
  •  Developement and Application of High Pressure Multi-Dimensional NMR SpectroscopyPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  生体系におけるNOの合成と反応及びその検出

    • Principal Investigator
      北川 禎三
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Okazaki National Research Institutes
  •  タンパク質立体構造の構築原理

    • Principal Investigator
      GO Nobuhiro
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Kyoto University
  •  Studies on Structures and Specific Functions in Bioinoganic Chemistry

    • Principal Investigator
      YAMAUCHI Osamu
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Adaptive design of biopolymers by evolutionary molecular engineering

    • Principal Investigator
      HUSIMI Yuzuru
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      Saitama University
  •  金属蛋白質の多元的構造と反応過程制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  時間分割ラウエ法利用研究

    • Principal Investigator
      三井 幸雄
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagaoka University of Technology
  •  MECHANISM OF OXYGEN ACTIVATION BY IRON-CHLORIN COMPLEXES AND THEIR REACTIVITIES.

    • Principal Investigator
      WATANABE Yoshihito
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Inorganic chemistry
    • Research Institution
      OKAZAKI NATIONAL RESEARCH INSTITUTES
      Kyoto University
  •  生物無機化学における構造と特異機能の研究

    • Principal Investigator
      山内 脩
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  金属蛋白質の多元的構造と反応過程制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  生体系における酸素活性化とその制御の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Keio University
  •  Structural and Functional Analysis of Hemoproteins Under High Pressure by Las Photolysis MeasurementsPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物理化学一般
    • Research Institution
      KYOTO UNIVERSITY
  •  チトクロ-ムPー450の分子生物学・機能の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Keio University
  •  色素置換ヘム蛋白質における光電子移動反応の動的制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  生物無機化学における構造と特異機能の研究

    • Principal Investigator
      YAMAUCHI Osamu
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Nagoya University
  •  Japan-Germany/Japan-U. K. Cooperative Project on Bioscience with Special Reference to Protein Recognition

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Quantum Theory and Spectroscopy of Proteins as Biomachines

    • Principal Investigator
      KITAGAWA Teizo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      Okazaki National Research Institutes, Institute for Molecular Science
  •  表面-分子相互作用系の電子状態とメカニズム解析

    • Principal Investigator
      中辻 博
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  チトクロームPー450の分子生物学:機能の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Keio University
  •  生体系金属イオンの配位環境と生理活性

    • Principal Investigator
      山内 脩
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      無機・錯塩・放射化学
    • Research Institution
      Nagoya University
  •  表面-分子相互作用系の電子状態とメカニズム解析

    • Principal Investigator
      中辻 博
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  チトクロームPー450の分子生物学:機能の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Keio University
  •  高圧NMR法によるタンパク質の動的構造の研究Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  高圧下におけるNMR、分子分光併用測定法の開発とその応用Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      物理化学一般
    • Research Institution
      Kyoto University
  •  無機材料設計のための電子論

    • Principal Investigator
      YONEZAWA Teijiro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      無機工業化学
    • Research Institution
      Kyoto University
  •  Studies on the Molecular Engineering of Functional Regulations of Synthetic Pigment Substituted HemoproteinsPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      工業物理化学
    • Research Institution
      Kyoto University
  • 1.  KITAGAWA Teizo (40029955)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  ISHIMORI Koichiro (20192487)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  石村 巽 (40025599)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  NISHINO Takeshi (40094312)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Yoshihito (10201245)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  TAKAHASHI Satoshi (30283641)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  YAMAUCHI Osamu (70029643)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Shinichiro (70116052)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  GO Nobuhiro (50011549)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  TANAKA Koji (00029274)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  MIKI Kunio (10116105)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  AKUTSU Hideo (60029965)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  中辻 博 (90026211)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
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  • 111.  FUTAI Masamitsu
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