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Shibata Kenichiro  柴田 健一郎

ORCIDConnect your ORCID iD *help
… Alternative Names

柴田 健一郎  シバタ ケンイチロウ

SHIBATA Kenichiro  柴田 健一郎

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Researcher Number 50145265
Other IDs
External Links
Affiliation (Current) 2022: 北海道大学, 歯学研究院, 名誉教授
Affiliation (based on the past Project Information) *help 2019 – 2021: 北海道大学, 歯学研究院, 名誉教授
2013: 北海道大学, 大学院歯学研究科, 教授
2011 – 2013: 北海道大学, 歯学研究科(研究院), 教授
2007 – 2013: Hokkaido University, Graduate school of Dental medicine, professor
2006: Hokkaido University, Graduate School of Dental Medicine, Professor., 大学院歯学研究科, 教授 … More
2001 – 2005: 北海道大学, 大学院・歯学研究科, 教授
2000: Hokkaido Univ.Grad.Sch.Dent.Med.Asso.Prof., 大学院・歯学研究科, 助教授
1996 – 1999: Hokkaido Univ.Sch.Dent., Associate Prof., 歯学部, 助教授
1992 – 1995: 北海道大学, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) / Morphological basic dentistry / Morphological basic dentistry
Except Principal Investigator
Morphological basic dentistry / Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) / Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related
Keywords
Principal Investigator
リポタンパク質 / FSL-1 / TLR2 / DC-SIGN / Toll-like receptor / リポペプチド / 炎症 / リポペプチドFSL-1 / アポトーシス / IL-6 … More / IL-8 / apoptosis / Mycoplasma salivarium / ICAM-1 / Toll様受容体 / lipopeptides / Dectin-1 / CD14 / 免疫 / 感染 / XS106細胞 / リポアラビノマンナン / MDDC / Man_9(GLcNAc)_2 / ガン / 制御性T細胞 / 抗腫瘍活性 / 口腔細菌 / 口腔レンサ球菌 / B16メラノーマ / NK細胞 / 腫瘍 / マイコプラズマ / ホスホリパーゼC / Tリンパ球 / TNF-α / 線維芽細胞 / TNFα / 口腔マイコプラズマ / コンカナバリンA / mycoplasma / phospholipase C / T cells / TNF-alpha / fibroblast / 歯肉線維芽細胞 / 口腔微生物 / 接着因子 / gingival fibroblasts / lipoprotein / lipopeptide / 構造と生物活性 / Lipoproteins / Toll-like receptors / Toll様受容体2 / ロイシンリッチリピート / ペプチドグリカン / Toll-like receptor 2 / lipopeoteins / Leucine-rich repeats / 細菌貧食 / Toll様受容体(TLR) / Th2応答 / 微生物貪食 / 大腸菌由来LPS / phagocytosis / Th2 response … More
Except Principal Investigator
IL-6 / Mycoplasma salivarium / 自然免疫 / マイコプラズマ / Mycoplasma orale / TLR / 細胞膜タンパク質 / MHC class II抗原 / 免疫組織化学 / Toll様受容体 / マイコプラズマ汚染 / 培養細胞 / Mycoplasma fermentans / 口腔マイコプラズマ / IL-8 / PCR / リンパ管 / PECAM-1 / ICAM-1 / ELAM-1 / デスモプラキン / リンパ管内皮細胞 / VEGF / IGF / CCL21 / 転写因子 / IgG Fe結合活性 / マイト-ジエン / 口腔粘膜症患 / γδT細胞 / anti-pan-γδTCR / anti-vγ4 / TNF・α / TFN-γ / 扁平苔癬 / 舌癌 / 口腔粘膜疾患 / 微生物由来リポペプチドFSL-1 / アジュバント / 坑腫瘍免疫 / 制御性T細胞 / 抗体依存性細胞傷害活性 / 唾液腺 / シェーグレン症候群 / 自己免疫 / IgA / B細胞 / IgA / MyD88 / TACI / 粘膜免疫 / B細胞 / MyD88 / TACI / 光線力学療法 / aPDT / contamination / 抗コレステロール抗体 / MHCクラスII抗原の発現 / IgG Fc結合性タンパク質 / IgG Fc結合活性 / 自己抗体 / Raji細胞 / IgG Fc レセプター / IgG:Fc結合活性 / コレステロール / ヤルジオライピン / 膜タンパク質 / IgG Fc / Antibody to cholesterol / Expression of MHC class II atigen / IgG Fc binding protein / IgG Fc binding activity / Autoantibody / Raji cell / マイコプラズマ除 / HeLa細胞 / 培養温度 / 細胞培養 / マイコプラズマの除去 / 加熱 / 酸ホスファターゼ / タンパク・チロシン・ホスファターゼ / マイコプラズマ除去 / Cell culture / Mycoplasma contamination / Elimination of mycoplasmas / HeLa cell / Incubation temperature / コラゲナーゼ / 線維芽細胞 / マイコプラズマ感染 / 誘導 / コラゲナーゼ放出 / Oral Mycoplasma / Collagenase / Fibroblast / T細胞 / コンカナバリンA / アポトーシス / TNFα / 歯肉線維芽細胞 / TNF-α / Oral mycoplasmas / T cells / concanavalin A / apoptosis / TNFalpha / 歯髄 / 感染防禦機構 / 白血球接着因子 / 白血球背着因子 / G-CSF / GM-CSF / 感染防御 / 微小循環 / VCAM-1 / IgGFc / 細菌学 / Dental pulp / Immuno-defence system / Leukocyte adhesion molecule / Lymphatic vessel / Immuno-histochemistry / 口腔扁平上皮癌 / リンパ管新生 / desmoplakin / V28 / TLR2 / TLR4 / CCR7 / プラコグロビン / デスモコリン / デスモグレイン / p53 / Lymphatic endothelium / Oral squamous cell carcinoma / Lymphangiogenesis / 硬化性骨病変 / 骨芽細胞 / 線維芽細胞増殖因子2(FGF-2) / 石灰化 / Toll like receptor / Condensing osteitis / アデノウイルス / Adenovirus / Innate immune / Transcription factor / インフラマソーム / IL-1β / ジアシルリポペプチドFSL-1 / gasdermin D / pyroptosome / IL-1β細胞外分泌 Less
  • Research Projects

    (22 results)
  • Research Products

    (110 results)
  • Co-Researchers

    (26 People)
  •  インフラマソームによる新規炎症制御機構の解明

    • Principal Investigator
      佐伯 歩
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Hokkaido University
  •  口腔レンサ球菌に対する経口免疫寛容Principal Investigator

    • Principal Investigator
      柴田 健一郎
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Regulatory effect of the TLR/TACI-MyD88 signaling pathway on immune responses associated with the homing of IgA-producing B cells into salivary glands

    • Principal Investigator
      INTO Takeshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Asahi University
  •  Development of a method to remove mycoplasmas from the contaminated cell cultures using antimicrobial photodynamic therapy

    • Principal Investigator
      HASEBE Akira
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Activation of regulatory T cells by oral inhabitant bacteria and relationship of their existence and growth of cancerPrincipal Investigator

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  A crosstalk between Toll-like receptor and C-type lectinPrincipal Investigator

    • Principal Investigator
      SHIBATA Kenichiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Effects of microbial lipoproteins and lipopeptides on the growthof tumor

    • Principal Investigator
      木浦 和人
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Cross-talk between viral. infection and bacterial infection in oral region

    • Principal Investigator
      YASUDA Motoaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Roles of Toll-like receptors in bacterial phagocytosisPrincipal Investigator

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Mechanism of condensing osteitis crisis following viral infection through toll-like receptors

    • Principal Investigator
      DEYAMA Yoshiaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Studies on recognition mechanism of oral microbes-derived lipopeptides by Toll-like receptorsPrincipal Investigator

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  THE STUDY FOR REGULATION OF THE DEVELOPMENTAL DYNAMICS OF LYMPHATIC SYSTEMS IN HEAD AND NECK, AND FOR THE ADHESION SYSTEMS OF CANCER CELLS TO LYMPHATIC ENDOTHELIUM

    • Principal Investigator
      YOSHIDA Shigemitsu
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Structural analysis of lipope microbes responsible for binding to Toll-like receptorsPrincipal Investigator

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Physiological and pathological roles of adhesion molecules expressed on gingival fibroblasts in response to oral microbesPrincipal Investigator

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  口腔粘膜症患の発症機構におけるγδT細胞の関与に関する研究

    • Principal Investigator
      YOSHIDA Shigemitsu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Hokkaido University
  •  Immuno-histochemical and microbiological study on the relationships between microcirculatory system and immuno-defence system in the dental pulp.

    • Principal Investigator
      YOSHIDA Shigemitsu
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Morphological basic dentistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Apoptosis of immuno-competent cells induced by oral mycoplasmas

    • Principal Investigator
      KIKUCHI Hiroko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Hokkaido University
  •  Activation of T and B lymphocytes by oral mycoplasmasPrincipal Investigator

    • Principal Investigator
      SHIBATA Kenichiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  口腔マイコプラズマ膜蛋白質のIgG Fe部位との結合様式と生物学的活性

    • Principal Investigator
      WWATANABE Tsuguo
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Discharge of collagenase from a gingival fibroblast infected with oral mycoplasma

    • Principal Investigator
      KIKUCHI Hiroko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Mechanisms of induction of actoantibodies by oral mycoplasemas

    • Principal Investigator
      WWATANABE Tsuguo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Elimination of mycoplasmas contaminating cell cultures.

    • Principal Investigator
      WATANABE Tsuguo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University

All 2021 2020 2019 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Lipoprotein extraction from microbial membrane and lipoprotein/lipopeptide transfection into mammalian cells2021

    • Author(s)
      Hasebe A., Saeki A., Shibata K. I.
    • Journal Title

      Methods in Molecular Biology

      Volume: 2021;2210 Pages: 195-204

    • DOI

      10.1007/978-1-0716-0939-2_19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K10066, KAKENHI-PROJECT-16H06280
  • [Journal Article] Gasdermin D‐independent release of interleukin‐1 β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides2020

    • Author(s)
      Saeki A., Tsuchiya K., Suda T., Into T., Hasebe A., Suzuki T., Shibata K. -i.
    • Journal Title

      Immunology

      Volume: 161 Pages: 114-122

    • DOI

      10.1111/imm.13230

    • NAID

      120007151366

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07106, KAKENHI-PROJECT-19K10066, KAKENHI-PROJECT-19KK0217, KAKENHI-PROJECT-19H03467, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-20H03484
  • [Journal Article] Toll-like receptor 2 - mediated modulation of growth and functions of regulatory T cells by oral streptococci2013

    • Author(s)
      A. Saeki, T. Segawa, T. Abe, M. Sugiyama, T. Arimoto, H. Hara, A.Hasebe, M. Ohtani, N. Tanizume, M. Ohuchi, H. Kataoka, M. Kawanami, A. Yokoyama and K. Shibata.
    • Journal Title

      molecular oral microbiology

      Volume: 未定 Pages: 1-14

    • DOI

      10.1111/omi.12023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352, KAKENHI-PROJECT-23792113, KAKENHI-PROJECT-24890006
  • [Journal Article] Mycoplasma Removal from Cell Culture Using Antimicrobial Photodynamic Therapy2013

    • Author(s)
      Akira Hasebe, Isao Ishikawa, Haque M. Shamsul, Makoto Ohtani, Taku Segawa, Ayumi Saeki, Naoho Tanizume, Manabu Oouchi, Yoshihide Okagami, Teruo Okano, Ken-ichiro Shibata
    • Journal Title

      Photomed Laser Surg

      Volume: 31 Pages: 125-131

    • DOI

      10.1089/pho.2012.3372

    • NAID

      120005372314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592692, KAKENHI-PROJECT-24890006
  • [Journal Article] Mycoplasma removal from cell culture using antimicrobial photodynamic therapy2013

    • Author(s)
      Akira Hasebe, Isao Ishikawa, Haque M. Shamsul, Makoto Ohtani, Taku Segawa, Ayumi Saeki, Naoho Tanizume, Manabu Oouchi, Yoshihide Okagami, Teruo Okano, and Ken-ichiro Shibata
    • Journal Title

      Photomedicine and Laser Surgery

      Volume: Vol. 31, No. 3

    • NAID

      120005372314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592692
  • [Journal Article] Mycoplasma Removal from Cell Culture Using Antimicrobial Photodynamic Therapy2013

    • Author(s)
      A Hasebe, I Ishikawa, H M Shamsul, M Ohtani, T Segawa, A Saeki, N Tanizume, M Oouchi, Y Okagami, T Okano, and K Shibata
    • Journal Title

      Photomed Laser Surg

      Volume: 31 Pages: 1-7

    • NAID

      120005372314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Toll-like receptor 2-mediated modulation of growth and functions of regulatory T cells by oral streptococci.2013

    • Author(s)
      A. Saeki, T. Segawa, T. Abe, M. Sugiyama, T. Arimoto, H. Hara, A.Hasebe, M. Ohtani, N. Tanizume, M. Ohuchi, H. Kataoka, M. Kawanami, A. Yokoyama and K. Shibata.
    • Journal Title

      Mol Oral Microbiol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Involvement of suppressor of cytokine signaling-1-mediated degradation ofMyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signaling by the murine C-type lectinSIGNR1-mediated signaling2012

    • Author(s)
      M Ohtani , M Iyori , A Saeki, N Tanizume, T Into, A Hasebe , Y Totsuka and K Shibata
    • Journal Title

      Cell Microbiol

      Volume: 14(1) Pages: 40-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A202012

    • Author(s)
      Inomata M., Niida S., Shibata K., and Into T
    • Journal Title

      Cell. Mol. Life Sci

      Volume: 69(6) Pages: 963-979

    • Data Source
      KAKENHI-PROJECT-23390431
  • [Journal Article] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20.2012

    • Author(s)
      M Inomata, Niida S., Shibata K, and Into T
    • Journal Title

      Cell Mol Life Sci

      Volume: 69(6) Pages: 963-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Involvement of suppressor of cytokine signaling-1-mediated degradation of MyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signaling by the murine C-type lectin SIGNR1-mediated signaling2012

    • Author(s)
      M Ohtani, M Iyori, A Saeki, N Tanizume, T Into, A Hasebe, Y Totsuka, K Shibata
    • Journal Title

      Cellular Microbiology

      Volume: 14 Pages: 40-57

    • DOI

      10.1111/j.1462-5822.2011.01695.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] 口腔マイコプラズマ由来ジアシルリポペプチドFSL-1のin vivoにおける抗腫瘍活性」化学療法の領域2012

    • Author(s)
      柴田健一郎
    • Journal Title

      医薬ジャーナル社

      Volume: vol.28 Pages: 97-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20.2012

    • Author(s)
      Inomata, M., Niida, S., Shibata, K., Into, T
    • Journal Title

      Cell Mol. Life Sci.

      Volume: 69 Pages: 963-979

    • DOI

      10.1007/s00018-011-0819-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352, KAKENHI-PROJECT-23390431, KAKENHI-PROJECT-23792158
  • [Journal Article] 口腔マイコプラズマ由来ジアシルリポペプチドFSL-1のin vivo に2012

    • Author(s)
      柴田 健一郎
    • Journal Title

      化学療法の領域

      Volume: 28 Pages: 97-104

    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] In vivo anti-and pro-tumour activities of the TLR2 ligandFSL-12011

    • Author(s)
      K Kiura, A Hasebe, A Saeki, T Segawa, F Okada, H M Shamsul, M Ohtani , T Into, N Inoue, M Wakita, K Shibata
    • Journal Title

      Immunobiology

      Volume: 216 Pages: 891-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] In vivo anti- and pro-tumour activities of the TLR2 ligand FSL-12011

    • Author(s)
      K Kiura, A Hasebe, A Saeki, T Segawa, F Okada, H M Shamsul, M Ohtani, T Into, N Inoue, M Wakita, K Shibata
    • Journal Title

      Immunobiology

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Effect of the antimicrobial peptide LL-37 on Toll-like receptor 2-, 3- and 4- triggered expression of IL-6, IL-8 and CXCL10 in human gingival fibroblasts2010

    • Author(s)
      Into T., Inomata M, Shibata K.
    • Journal Title

      Mol.Oral Microbiol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] The TLR2 ligand FSL-1 is internalized via clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010

    • Author(s)
      HM.Shamsul, A.Hasebe, M.Iyori, M.Ohtani, K.Kiura, D.Zhang, Y Totsuka, K.Shibata
    • Journal Title

      Immunology (In press)

    • NAID

      120002414898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] The TLR2 ligand FSL-1 is internalized via clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010

    • Author(s)
      HM Shamsul, A Hasebe, M Iyori, M Ohtani, K Kiura, D Zhang, Y Totsuka, K Shibata
    • Journal Title

      Immunology 130

      Pages: 262-272

    • NAID

      120002414898

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Novel function of transcription factor ATF5 : blockade of p53-dependent apoptosis induced by ionizing irradiation.2009

    • Author(s)
      Nishioka T, Miyai Y, Haga H, Kawabata K, Shirato H, Homma A, Shibata K, Yasuda M.
    • Journal Title

      Cell Struct Funct 34

      Pages: 17-22

    • NAID

      130004137541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] A role of the Ca^<2+> binding site ofDC-SIGN in the phagocytosis of E. coli.2008

    • Author(s)
      Mitsuhiro Iyori, Makoto Ohtani , Akira Hasebe, Yasunori Totsuka and K. Shibata
    • Journal Title

      Biochem. Biophy. Res. Comm. 377(2)

      Pages: 367-372

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] A role of the Ca^<2+> binding site of DC-SIGN in the phagocytosis of E. coli2008

    • Author(s)
      M Iyori, M Ohtani, A Hasebe, Y Totsuka and K Shibata
    • Journal Title

      Biochem. Biophy. Res. Comm. 377

      Pages: 367-372

    • NAID

      120002414904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] A role of the Ca2+ binding site of DC-SIGN in the phagocytosis of E. coli.2008

    • Author(s)
      M Iyori, M Ohtani, A Hasebe, Y Totsuka, K Shibata
    • Journal Title

      Biochem. Biophy. Res. Comm 377(2)

      Pages: 367-372

    • NAID

      120002414904

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Resveratrol modulatesphagocytosis of bacteria through an NF-・B-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, Haque M Shamsul,K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata
    • Journal Title

      Antimicrob Agents Chemother 52(1)

      Pages: 121-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] Regulation of MyD88-dependent signaling events by S-nitrosylation retards Toll-like receptor signal transduction and initiation of acute-phase immune responses2008

    • Author(s)
      Into T., Inomata M., Nakashima M., Shibata K., Hacker H., and Matsushita K.
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 1338-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Reseveratrol modulates phagocytosis of bacteria through an NF-κB-dependent gene program.2008

    • Author(s)
      M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata*.
    • Journal Title

      Antimicrobial Agents Chemotherapy 52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-κB-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, HM Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, K Shibata
    • Journal Title

      Antimicrob. Agents. Chemother 52(1)

      Pages: 121-127

    • NAID

      120002451617

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-kB-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata*
    • Journal Title

      Antimicrobial Agents Chemotherapy 52

      Pages: 121-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-kB-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata
    • Journal Title

      Antimicrobial Agents Chemotherapy 52

      Pages: 121-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] Regulation of MyD88-dependentsignaling events by S-nitrosylationretards Toll-like receptor signaltransduction and initiation ofacute-phase immune responses.2008

    • Author(s)
      Into T., Inomata M., Nakashima M., Shibata K., Hacker H., and Matsushita K
    • Journal Title

      Mol. Cell. Biol 28(4)

      Pages: 1338-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] The diacylatedlipopeptide FSL-1 enhancesphagocytosis of bacteria bymacrophages through Toll-like receptor2-mediated signaling pathway.2007

    • Author(s)
      Mae M, Iyori M, Yasuda M, Shamsul H, Kataoka H, Hasebe A, Kiura K, TotsukaY, Shibata K.
    • Journal Title

      FEMS Immunol. Med. Microbiol 49

      Pages: 398-409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through Toll-like receptor 2-mediated signaling pathway.2007

    • Author(s)
      Mae M, Iyori M, Yasuda M, Shamsul H, Kataoka H, Hasebe A, Kiura K, Totsuka Y, Shibata K.
    • Journal Title

      FEMS Immunol. Med. Microbiol 49

      Pages: 398-409

    • NAID

      120002451616

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] Synthesis andCharacterization of a dipalmitoylatedlipopeptide derived from paralogouslipoproteins of Mycoplasma pneumoniae2007

    • Author(s)
      Into T., Dohkan J., Inomata M., Nakashima M., Shibata K., and Matsushita K.
    • Journal Title

      Infect. Immun 75(5)

      Pages: 2253-2259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through Toll-like receptor 2-mediated signaling pathway2007

    • Author(s)
      M Mae, M Iyori, M Yasuda, HM Shamsul, H Kataoka, A Hasebe, K Kiura, Y Totsuka, K Shibata
    • Journal Title

      FEMS. Immunol. Med. Microbiol 49

      Pages: 398-409

    • NAID

      120002451616

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through Toll-like receptor 2-mediated signaling pathway2007

    • Author(s)
      Mae M, Iyori M, Yasuda M, Shamsul H, Kataoka H, Hasebe A, Kiura K, Totsuka Y, Shibata K
    • Journal Title

      FEMS Immunology and Medical Microbiology 49

      Pages: 398-409

    • NAID

      120002451616

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] The 6-fluoro-8- methoxy quinolonegatifloxacin down-regulatesinterleukin-8 production in prostatecell line PC-3.2007

    • Author(s)
      Takeyama K, Mitsuzawa H, Nishitani C, Shimizu T, Sano H, Kunishima Y, Takahashi S, Hotta H, Matsukawa M, Shibata K, Tsukamoto T, Kuroki Y.
    • Journal Title

      AntimicrobAgents Chemother. 51

      Pages: 162-168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] Pathogen recognition byToll-like receptor 2 activatesWeibel-Palade body exocytosis in humanaortic endothelial cells.2007

    • Author(s)
      Into T, Kanno Y, Dohkan JI, NakashimaM, Inomata M, Shibata K, Lowenstein CJ, Matsushita K.
    • Journal Title

      J Biol Chem. 282(11)

      Pages: 8134-8141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR22006

    • Author(s)
      Kataoka H., Yasuda M., Iyori M., Kiura K., Narita M., Nakata T., Shibata K.
    • Journal Title

      Cellular Microbiology 8

      Pages: 1199-1207

    • NAID

      120000955850

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex.2006

    • Author(s)
      T.Nakata, M.Yasuda, M.Fujita, H.Kataoka, K.Kiura, H.Sano, K.Shibata*.
    • Journal Title

      Cell. Microbiol 8

      Pages: 1899-1909

    • NAID

      120000955848

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] The diacylated lipopeptide FSL-1 induces TLR2-mediated Th2 responses2006

    • Author(s)
      K.Kiura, H.Kataoka, M.Yasuda, N.Inoue, K.Shibata
    • Journal Title

      FEMS Immunology and Medical Microbiology 48

      Pages: 44-55

    • NAID

      120002451618

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] The diacylated lipopeptide FSL-1 induces TLR2-mediated Th2 responses.2006

    • Author(s)
      K.Kiura, H.Kataoka, M.Yasuda, N.Inoue, K.Shibata*.
    • Journal Title

      FEMS Immunol. Med. Microbiol 48

      Pages: 44-55

    • NAID

      120002451618

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2.2006

    • Author(s)
      Kataoka H., Yasuda M., Iyori M., Kiura K., Narita M., Nakata T., Shibata K.
    • Journal Title

      Cell Microbiol 8

      Pages: 1199-1207

    • NAID

      120000955850

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex2006

    • Author(s)
      T.Nakata, M.Yasuda, M.Fujita, H.Kataoka, K.Kiura, H.Sano, K.Shibata
    • Journal Title

      Cellular Microbiology 8

      Pages: 1899-1909

    • NAID

      120000955848

    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] The synthetic analogue of mycoplasmal lipoprotein FSL-1 induces dendritic cell maturation through TLR22006

    • Author(s)
      Kiura K., Kataoka H., Nakata T., Into T., Yasuda M., Akira S., Inoue N., Shibata K.
    • Journal Title

      FEMS Immunology and Medical Microbiology 46

      Pages: 78-84

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex2006

    • Author(s)
      Nakata, M.Yasuda, M.Fujita, H.Kataoka, K.Kiura, H.Sano, K.Shibata^*
    • Journal Title

      Cellular Microbiology 8

      Pages: 1899-1909

    • NAID

      120000955848

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] The synthetic analogue of mycoplasmal lipoprotein FSL-1 induces dendritic cell maturation through TLR2.2006

    • Author(s)
      Kiura K., Kataoka H., Nakata T., Into T., Yasuda M.Akira S., Inoue N., Shibata K.
    • Journal Title

      FEMS Immunol. Med. Microbiol 46

      Pages: 78-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] Apoptosis signal-regulating kinase 1 (ASK1)-mediated sustained p38 MAPK activation regulates mycoplasmal lipoprotein- and staphylococcal peptidoglycan-triggered Toll-like receptor 2 signaling pathways.2005

    • Author(s)
      Into T, Shibata K.
    • Journal Title

      Cellular Microbiology 7・9

      Pages: 1305-1317

    • Data Source
      KAKENHI-PROJECT-17390498
  • [Journal Article] Structure-function relationship of mycoplasmal lipoproteins/lipopeptides and their recognition by Toll-like receptor 2.2005

    • Author(s)
      K Shibata, M Fujita, M Morita
    • Journal Title

      J Oral Biosci 46(3)

      Pages: 203-220

    • NAID

      110003166643

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Stimulation of human Toll-like receptor(TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappaB activation2004

    • Author(s)
      T.Into, K.Kiura, M.Yasuda, H.Kataoka, N.Inoue, A.Hasebe, K.Takeda, S.Akira, K.Shibata
    • Journal Title

      Cellular Microbiology 6(2)

      Pages: 187-199

    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Structure-function relationship of mycoplasmal lipoproteins/lipopeptides and their recognition by Toll-like receptor 22004

    • Author(s)
      K Shibata et al.
    • Journal Title

      J Oral Biosci 46(3)

      Pages: 203-220

    • NAID

      110003166643

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal disease.2004

    • Author(s)
      A Hasebe, A Yoshimura, T Into, H Kataoka, S Tanaka, S Arakawa, H Ishikura, DT Golenbock, T Sugaya, N Tsuchida, M Kawanami, Y Hara, K Shibata
    • Journal Title

      Infect Immun 72(3)

      Pages: 1318-1325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by Toll-like receptors 2 and 62004

    • Author(s)
      T.Okusawa, M.Fujita, ----K.Shibata
    • Journal Title

      Infection and Immunity 72・3

      Pages: 1657-1665

    • NAID

      120002451624

    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Possible roles of Toll-like receptor 2/6 and extracellular ATP in mycoplasmal lipoprpotein-induced cell activation and death2004

    • Author(s)
      T.Into, K.Shibata
    • Journal Title

      Journal of Oral Bioscience 46・4

      Pages: 278-288

    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by Toll-like receptors 2 and 6.2004

    • Author(s)
      T Okusawa, M Fujita, J Nakamura, T Into, M Yasuda, A Yoshimura, Y Hara, A Hasebe, DT Golenbock, M Morita, Y Kuroki, T Ogawa, K Shibata.
    • Journal Title

      Infect Immun 72(3)

      Pages: 1657-1665

    • NAID

      120002451624

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Possible roles of Toll-like receptor 2/6 and extra cellular ATP on mycoplasmal membrane linonrotein-induced cell activation and death.2004

    • Author(s)
      T Into, K Shibata
    • Journal Title

      J Oral Biosci 46(4)

      Pages: 278-288

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Structure-function relationship of mycoplasmal lipoproteins/lipopeptides and their recognition by Toll-like receptor 2.2004

    • Author(s)
      Ken-ichiro Shibata, Mari Fujita, Manabu Morita
    • Journal Title

      Journal of Oral Bioscience 46・3

      Pages: 203-220

    • NAID

      110003166643

    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappaB activation.2004

    • Author(s)
      T Into, K Kiura, M Yasuda, H Kataoka, N Inoue, A Hasebe, K Takeda, S Akira, K Shibata.
    • Journal Title

      Cell Microbiol 6(2)

      Pages: 187-199

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal disease2004

    • Author(s)
      A.Hasebe, A.Yoshimura-----K.Shibata
    • Journal Title

      Infection and Immunity 72・3

      Pages: 1318-1325

    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Involvement of leucine residues at positions 107,112 and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoproteins and liopeptides and Staphylococcus aureus peptidoglycans2003

    • Author(s)
      M.Fujita, T.Into, M.Yasuda, T.Okusawa, S.Hamahira, Y.Kuroki, A.Eto, T.Nisizawa, M.Morita, K.Shibata.
    • Journal Title

      Journal of Immunology 171

      Pages: 3675-3683

    • Data Source
      KAKENHI-PROJECT-15390549
  • [Journal Article] Involvement of leucine residues at positions 107,112 and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoproteins and lipopeptides and Staphylococcus aureus peptidoglycans.2003

    • Author(s)
      M Fujita, T Into, M Yasuda, T Okusawa, S Hamahira, Y Kuroki, A Eto, T Nisizawa, M Morita, K Shibata.
    • Journal Title

      J Immunol. 171

      Pages: 3675-3683

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390549
  • [Presentation] The effects of Candida albicans oral ingestion on intestinal microbial flora2020

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第62回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] Activation of NLRP3 inflammasome by mycoplasmal lipopeptides only through the TLR2-mediated signals2020

    • Author(s)
      佐伯 歩、引頭 毅、長谷部 晃、柴田 健一郎
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] マイコプラズマ由来リポタンパク質・リポペプチドによるNLRP3インフラマソーム活性化におけるTLR2の役割2020

    • Author(s)
      佐伯 歩,引頭 毅,長谷部 晃,柴田 健一郎
    • Organizer
      第62回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] Candida albicans経口摂取が腸内細菌叢に及ぼす影響について2020

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第24回腸内細菌学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] How does the mycoplasmal lipopeptide FSL-1 induce IL-1beta release by living macrophages?2019

    • Author(s)
      佐伯 歩、土屋 晃介、須田 貴司、引頭 毅、長谷部 晃、鈴木 敏彦、柴田 健一郎
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] Fine tuning of gene expression in eukaryotes by Mycoplasmal DNA sequences2019

    • Author(s)
      安田 元昭、長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] マイコプラズマDNAによる真核細胞遺伝子発現のファインチューニング2019

    • Author(s)
      安田 元昭、長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      日本マイコプラズマ学会第46回学術集会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] マイコプラズマ由来リポタンパク質/リポペプチドにより誘導される生きたマクロファージからのIL-1β放出細胞外分泌機構2019

    • Author(s)
      佐伯 歩、引頭 毅、長谷部 晃、鈴木 敏彦、柴田 健一郎
    • Organizer
      第61回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] マイコプラズマ由来リポタンパク/リポペプチドはどのようなメカニズムで生きたマクロファージにIL-1β放出を誘導するのか2019

    • Author(s)
      佐伯 歩、長谷部 晃、柴田 健一郎
    • Organizer
      日本マイコプラズマ学会第46回学術集会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] マイコプラズマ由来リポタンパク質/リポペプチドにより誘導されるマクロファージからのIL-1β放出細胞外分泌機構2019

    • Author(s)
      佐伯 歩、土屋 晃介、須田 貴司、引頭 毅、長谷部 晃、鈴木 敏彦、柴田 健一郎
    • Organizer
      第85回日本細菌学会北海道支部学術総会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] Candida albicans oral ingestion affects intestinal microbial flora2019

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-19K10066
  • [Presentation] Recognition of oral streptococci by intracellular sensors, NODs and inflammasome2013

    • Author(s)
      Ayumi Saeki、Akira Hasebe、Futoshi Nakazawa, Ken-ichiro Shibata
    • Organizer
      日本細菌学会
    • Place of Presentation
      幕張メッセ国際会議場(千葉市)
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] シグナル伝達分子MyD88は顎下腺におけるB-1細胞浸潤の制御と唾液中の抗体産生の調節に関与する2013

    • Author(s)
      引頭 毅、滝川俊也、柴田健一郎
    • Organizer
      歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23390431
  • [Presentation] Expression and function of Toll-like receptors and NK activity in oral candidasis and aging2013

    • Author(s)
      Manabu Ouuchi, Ayumi Saeki, Ken-ichiro Shibata
    • Organizer
      日本細菌学会
    • Place of Presentation
      幕張メッセ国際会議場(千葉市)
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Expression and function of Toll-like receptors and NK activity in oral candidiasis and aging2013

    • Author(s)
      大内学,佐伯歩、柴田健一郎
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ国際会議場,千葉
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Recognition of oralstreptococci by intracellular sensorsNODs, and inflammasome2013

    • Author(s)
      佐伯歩、大谷誠、長谷部晃、中澤太、柴田健一郎
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ国際会議場,千葉
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔レンサ球菌によるインフラマゾームの活性化2013

    • Author(s)
      佐伯歩、柴田健一郎
    • Organizer
      第5回「口腔環境制御研究」カテゴリー集会
    • Place of Presentation
      長崎大学,長崎
    • Year and Date
      2013-02-01
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌の抗腫瘍活性2012

    • Author(s)
      原 博志、佐伯 歩、長谷部 晃、柴田 健一郎.
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      奥羽大学(郡山)
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌の抗腫瘍活性2012

    • Author(s)
      原博志、佐伯歩、長谷部晃、柴田健一郎
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      奥羽大学,郡山
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌のパターン認識受容体による認識とインフラマゾームの活性化2012

    • Author(s)
      佐伯歩、杉山正博、瀬川卓、長谷部晃、北川善政、柴田健一郎
    • Organizer
      第79回日本細菌学会北海道支部学術総会.
    • Place of Presentation
      とかちプラザ,帯広
    • Year and Date
      2012-08-29
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 微生物由来リポタンパク質・リポペプチドの抗腫瘍活性2012

    • Author(s)
      原博志、佐伯歩、長谷部晃、柴田健一郎
    • Organizer
      第79回日本細菌学会北海道支部学術総会
    • Place of Presentation
      とかちプラザ,帯広
    • Year and Date
      2012-08-29
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] MyD88 deficiency causes accumulation of B-1a cells in submandibular glands2012

    • Author(s)
      Takeshi Into, Megumi Inomata, Ken-ichiro Shibata
    • Organizer
      日本免疫学会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 制御性T細胞(Treg)の免疫抑制活性に及ぼす口腔連鎖球菌の影響2011

    • Author(s)
      佐伯歩、瀬川卓、片岡嗣雄、長谷部晃、有本隆文、五十嵐武、川浪雅光、横山敦郎、柴田健一郎.
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場,岐阜
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Roles of the src family kinase lck in Toll-like receptor 2 signaling triggered by stimulation with a diacylated lipopeptide FSL-1.2011

    • Author(s)
      Akira Hasebe, Naoho Tanizume, Makoto Ohtani, Ken-Ichiro Shibata.
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Data Source
      KAKENHI-PROJECT-23592692
  • [Presentation] 口腔連鎖球菌の生体からの排除におけるリポタンパク質の影響2011

    • Author(s)
      瀬川卓、長谷部晃、佐伯歩、片岡嗣雄、有本隆文、五十嵐武、横山敦郎、川浪雅光、柴田健一郎.
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場,岐阜
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Effects of mycoplasma cells and lipopeptides on the in vivo growth of tumor in mice2011

    • Author(s)
      Ken-Ichiro Shibata
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(札幌市)(招請講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 微生物由来リポタンパク質のToll-like receptorによる認識とその生物活性2010

    • Author(s)
      柴田健一郎
    • Organizer
      第78回日本細菌学会北海道支部総会
    • Place of Presentation
      酪農学園大学(江別市) 招待講演
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Downregulation of the TLR2-mediated signal by the DC-SIGN ligand Man-LAM2009

    • Author(s)
      M Ohtani, A Hasebe, M Iyori, MS Haque, Y Totsuka, K Shibata
    • Organizer
      The 96th Annual Meeting of The American Association of Immunologists
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] Anti-and pro-tumor activities of the TLR2 ligand FSL-12009

    • Author(s)
      K Shibata, K Kiura, A Hasebe, M Iyori, MS Haque, M Ohtani
    • Organizer
      The 96th Annual Meeting of The American Association of Immunologists
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] 9件)(1)柴田健一郎.マイコプラズマ由来リポタンパク質-リポペプチドのユニークな生物活性2009

    • Author(s)
      柴田健一郎
    • Organizer
      日本マイコプラズマ学会第36回学術集会講演要旨集:27
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] How is the diacylated lipopeptide FSL-1processed after recognition by TLR2?2009

    • Author(s)
      MS Haque, A Hasebe, M Iyori, K Kiura, M Ohtani, K. Shibata
    • Organizer
      he 96th Annual Meeting of The American Association of Immunologists
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] 腫瘍の増殖に及ぼすジアシルリポペプチドFSL-1の影響2008

    • Author(s)
      木浦 和人、柴田 健一郎
    • Organizer
      自然免疫の最前線-3学会合同大会2008-第73回日本インターフェロン・サイトカイン学会学術集会・第19回日本生体防御学会学術総会・第45回補体シンポジウム(講演集)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] 腫瘍の増殖に及ぼすジアシルリポペプチドFSL-1の影響., 自然免疫の最前線-3学会合同大会2008-2008

    • Author(s)
      木浦和人、柴田健一郎
    • Organizer
      第73回日本インターフェロン・サイトカイン学会学術集会・第19回日本生体防御学会学術総会・第45回補体シンポジウム
    • Place of Presentation
      札幌(北海道大学・学術交流会館)
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] ジアシルリポペプチドFSL-1 による制御性T細胞の増殖と腫瘍免疫応答の抑制2008

    • Author(s)
      木浦 和人、長谷部 晃、柴田 健一郎
    • Organizer
      日本マイコプラズマ学会第35回学術集会(講演要旨集)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] ジアシルリボペプチドFSL-1 による腫瘍増殖の抑制と促進2008

    • Author(s)
      木浦 和人、長谷部 晃、伊従 光洋、脇田 稔、安田 元昭、山本 恒之、井上 農夫男、柴田 健一郎
    • Organizer
      第75回日本細菌学会北海道支部学術総会(26-27)
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-08
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] Toll-like receptor 2とDC-SIGNシグナルのクロストーク2008

    • Author(s)
      大谷誠、伊従光洋、長谷部晃、木浦和人、戸塚靖則、柴田健一郎
    • Organizer
      日本マイコプラズマ学会第35回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] ジアシルリポペプチドFSL-1 による制御性T細胞の増殖と腫瘍免疫応答の抑制2008

    • Author(s)
      木浦 和人、長谷部 晃、大谷 誠、伊従 光洋、柴田 健一郎
    • Organizer
      第76回日本細菌学会北海道支部学術総会(抄録集 30)
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-06
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] Toll-like receptor 2シグナルに及ぼすDC-SIGNシグナルの影響(優秀ポスター賞受賞)2008

    • Author(s)
      大谷誠、伊従光洋、長谷部晃、木浦和人、戸塚靖則、柴田健一郎
    • Organizer
      第50回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-24
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] Anti- and pro-tumor activities of the mycoplasmal lipopeptide FSL-1 as a TLR2 ligand. Innate Immunity Symposium2008

    • Author(s)
      Shibata K. Kiura K
    • Organizer
      Regulation in Innate Immunity- from Recognition Molecules to Antimicrobial Peptides
    • Place of Presentation
      Shionogi Innovation Center for drug discovery, Hokkaido University
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] ジアシルリポペプチドFSL-1による制御性T細胞の増殖と腫瘍免疫応答の抑制2008

    • Author(s)
      木浦和人、長谷部晃、柴田健一郎
    • Organizer
      日本マイコプラズマ学会第35回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-31
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] Toll様受容体と C型レクチン受容体とのクロストーク2007

    • Author(s)
      柴田 健一郎
    • Organizer
      第49回歯科基礎医学会学術大会・総会
    • Place of Presentation
      北海道大学学術交流会館札幌
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] マイコプラズマ由来ジアシルリボペプチドFSL1 の腫瘍増殖に及ぼす影響2007

    • Author(s)
      木浦 和人、安田 元昭、長谷部 晃、伊従 光洋、脇田 稔、山本 恒之、井上 農夫男、柴田 健一郎
    • Organizer
      第49回歯科基礎医学会学術大会・総会(Journal of Oral Biosciences 49 Suppl : 131)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] ジアシルリポペプチドFSL-1 の腫瘍増殖に及ぼす影響2007

    • Author(s)
      木浦 和人、長谷部 晃、伊従 光洋、安田 元昭、大谷 誠、柴田 健一郎
    • Organizer
      第37回日本免疫学会総会・学術集会(日本免疫学会総会・学術集会記録 第37 巻 : 217)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] マイコプラズマ由来ジアシルリポペプチド FSL-1 の抗腫瘍活性2007

    • Author(s)
      木浦 和人、安田 元昭、長谷部 晃、伊従 光洋、脇田 稔、山本 恒之、井上 農夫男、柴田 健一郎
    • Organizer
      日本マイコプラズマ学会第34回学術集会(講演予稿集)
    • Place of Presentation
      和歌山
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] シグナル伝達分子MyD88 は顎下腺におけるB-1 細胞浸潤の制御と唾液中の抗体産生の調節に関与する

    • Author(s)
      引頭 毅, 滝川俊也, 柴田健一郎
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23390431
  • [Presentation] Myd88 deficiency causes acumulation of B-1a cells in submandibular glands

    • Author(s)
      Into T., Inomata, M., and Shibata K.
    • Organizer
      The 41st Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-23390431
  • [Presentation] Regulation of Toll-like receptor signaling by human NDP52-mediated selective autophagy

    • Author(s)
      Inomata, M., Shibata K., and Into T
    • Organizer
      The 40th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Chiba
    • Data Source
      KAKENHI-PROJECT-23390431
  • [Presentation] Myd88 deficiency suppresses acumulation of B-1a cells in submandibular glands

    • Author(s)
      Into T., Inomata, M., and Shibata K
    • Organizer
      The 41st Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-23390431
  • [Presentation] NDP52 は選択的オートファジーの誘導によってToll 様受容体シグナルを負に制御する

    • Author(s)
      猪俣 恵, 新飯田 俊平, 柴田健一郎, 引頭毅
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23390431
  • [Presentation] 抗菌ペプチドLL-37 は異種のToll 様受容体リガンドによる歯肉線維芽細胞の応答に対して異なる効果を発揮する

    • Author(s)
      引頭 毅, 猪俣 恵, 柴田健一郎, 村上幸孝
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23390431
  • 1.  WWATANABE Tsuguo (10064362)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  HASEBE Akira (90281815)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 42 results
  • 3.  YOSHIDA Shigemitsu (80174928)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  SAWA Yoshihiko (70271666)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  YASUDA Motoaki (90239765)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 6.  KIKUCHI Hiroko (30001944)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  YAMAOKA Yuji (50322821)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KUROKI Yoshio (70161784)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 9.  鈴木 正嗣 (90216440)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  INTO Takeshi (10360918)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 11.  TAKIGAWA Toshiya (90263095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  TAKAYAMA Eiji (70533446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  INOMATA Megumi (40553798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 14.  INOUE Satoshi (80184745)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MAKINO Shujiroh (30280853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIMURA Atsutoshi (70253680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  DEYAMA Yoshiaki (80271667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TOTSUKA Yasunori (00109456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SUZUKI Kuniaki (40133748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  DOMON Takafumi (50217618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YOSHIMURA Yoshitaka (30230816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  木浦 和人 (50435947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 23.  佐伯 歩 (70638345)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 24.  TSUCHIYA Kohsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  鈴木 敏彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  須田 貴司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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