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Hasebe Akira  長谷部 晃

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HASEBE Akira  長谷部 晃

長谷部 晃  ハセベ アキラ

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Researcher Number 90281815
Other IDs
External Links
Affiliation (Current) 2022: 北海道大学, 歯学研究院, 教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 北海道大学, 歯学研究院, 教授
2017 – 2018: 北海道大学, 歯学研究院, 助教
2016: 北海道大学, 歯学研究科, 助教
2011 – 2015: 北海道大学, 歯学研究科(研究院), 助教
2007 – 2012: Hokkaido University, 大学院・歯学研究科, 助教 … More
2008: Hokkaido University, 大学院歯学研究科, 助教
2003: 北大, 歯学研究科(研究院), 助手
2002: 北海道大学, 大学院・歯学研究科, 助手
1998 – 1999: 北海道大学, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related
Except Principal Investigator
Pathobiological dentistry/Dental radiology / Basic Section 57060:Surgical dentistry-related / Basic Section 57080:Social dentistry-related / 病態科学系歯学(含放射線系歯学) / Basic Section 55050:Anesthesiology-related
Keywords
Principal Investigator
TLR2 / Candida albicans / 口腔カンジダ症 / リポタンパク質 / 口腔細菌学 / マイコプラズマ / FSL-1 / 腸炎 / IL-6 / Mycoplasma salivarium … More / 細胞内成分 / Mycoplasma fermentans / 培養上清 / 歯周病 / Bacteroides forsythus / 炎症性サイトカイン / アポトーシス / 抗体価 / リポペプチド / ファゴサイトーシス / Rab protein / 自然免疫 / 付着因子 / クラスリン依存的 / CD14 / CD36 / 光線力学療法 / マイコプラズマ汚染 / 培養細胞 / aPDT / contamination / 経口免疫寛容 / カンジダ症 / 制御性T細胞 / 腸内細菌叢 / IgA / 短鎖脂肪酸 / マウス / DSS誘導性腸炎 / dysbiosis / 免疫学 / DSS誘導腸炎 / メタゲノム解析 / 口腔細菌叢 / 上皮間接着分子 / 腸内細菌 … More
Except Principal Investigator
炎症 / TLR2 / 制御性T細胞 / リポタンパク質 / Mycoplasma salivarium / ICAM-1 / 免疫 / 感染 / FSL-1 / DC-SIGN / XS106細胞 / リポアラビノマンナン / MDDC / Man_9(GLcNAc)_2 / 微生物由来リポペプチドFSL-1 / 自然免疫 / アジュバント / 坑腫瘍免疫 / 抗体依存性細胞傷害活性 / ガン / 抗腫瘍活性 / 口腔細菌 / 口腔レンサ球菌 / B16メラノーマ / NK細胞 / Toll-like receptor / リポペプチドFSL-1 / 腫瘍 / 歯肉線維芽細胞 / リポペプチド / 口腔微生物 / 接着因子 / gingival fibroblasts / lipoprotein / lipopeptide / 口腔がん / 舌がん / 口腔常在菌 / 頸部転移 / 悪性化 / リンパ節転移 / リンパ節転移メカニズム / 転移 / 予後予測マーカー / 歯周病 / 脳血管障害 / 死後画像 / 定量的PCR / P.gingivalis / 歯周病原性菌 / 全身麻酔薬 / 作用機序 / 脂質ラフト / バイオイメージング / パッチクランプ法 / マイクロバイオーム解析 / 口腔癌 / 唾液 / 炎症性サイトカイン / 歯周病菌 / 造影剤 / トレース Less
  • Research Projects

    (17 results)
  • Research Products

    (70 results)
  • Co-Researchers

    (20 People)
  •  脂質ラフトのバイオイメージングと電気生理学的手法による全身麻酔薬の作用機序研究

    • Principal Investigator
      長谷 由理
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hokkaido University
  •  Development of Oral Cancer Prevention Methods Based on Analysis of Oral Bacterial Flora and Inflammatory Cytokines in Saliva

    • Principal Investigator
      大賀 則孝
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Hokkaido University
  •  歯周病細菌の脳への移行トレース

    • Principal Investigator
      箕輪 和行
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Hokkaido University
  •  How oral candidiasis can exacerbate colitis?Principal Investigator

    • Principal Investigator
      長谷部 晃
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Hokkaido University
  •  全身主要血管壁内における歯周病原性菌の存在分布ー脳血管障害による死亡例をもとに

    • Principal Investigator
      竹内 明子
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Hokkaido University
  •  Association between oral bacteria and oral cancer metastasis

    • Principal Investigator
      大廣 洋一
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Hokkaido University
  •  Exploring the systemic effect on intestinal dysbiosis induced by oral Candida albicansPrincipal Investigator

    • Principal Investigator
      Hasebe Akira
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Can oral Candida albicans induce C. albicans specific colonic regulatory T cells?Principal Investigator

    • Principal Investigator
      Hasebe Akira
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Development of a method to remove mycoplasmas from the contaminated cell cultures using antimicrobial photodynamic therapyPrincipal Investigator

    • Principal Investigator
      HASEBE Akira
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Activation of regulatory T cells by oral inhabitant bacteria and relationship of their existence and growth of cancer

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  The roles of bacterial lipoproteins on bacterial invasion and on intracellular trafficking in host cellsPrincipal Investigator

    • Principal Investigator
      HASEBE Akira
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  A crosstalk between Toll-like receptor and C-type lectin

    • Principal Investigator
      SHIBATA Kenichiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Effects of microbial lipoproteins and lipopeptides on the growthof tumor

    • Principal Investigator
      木浦 和人
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Hokkaido University
  •  Studies on molecular mechanism of phagocytosis in innate immune systemPrincipal Investigator

    • Principal Investigator
      HASEBE Akira
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  歯周病克服への新たなアプローチを目指して〜歯周病原細菌由来リポタンパク質の研究Principal Investigator

    • Principal Investigator
      長谷部 晃
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  歯肉線維芽細胞にIL-6とIL-8を誘導するマイコプラズマ由来物質の精製と性状Principal Investigator

    • Principal Investigator
      長谷部 晃
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hokkaido University
  •  Physiological and pathological roles of adhesion molecules expressed on gingival fibroblasts in response to oral microbes

    • Principal Investigator
      SHIBATA Ken-ichiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      HOKKAIDO UNIVERSITY

All 2021 2019 2018 2017 2016 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Differences in interleukin-1β release-inducing activity of Candida albicans toward dendritic cells and macrophages2018

    • Author(s)
      Hasebe Akira、Saeki Ayumi、Yoshida Yasuhiro、Shibata Ken-ichiro
    • Journal Title

      Archives of Oral Biology

      Volume: 93 Pages: 115-125

    • DOI

      10.1016/j.archoralbio.2018.06.004

    • Data Source
      KAKENHI-PROJECT-17K11606
  • [Journal Article] Mycoplasma Removal from Cell Culture Using Antimicrobial Photodynamic Therapy2013

    • Author(s)
      A Hasebe, I Ishikawa, H M Shamsul, M Ohtani, T Segawa, A Saeki, N Tanizume, M Oouchi, Y Okagami, T Okano, and K Shibata
    • Journal Title

      Photomed Laser Surg

      Volume: 31 Pages: 1-7

    • NAID

      120005372314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Toll-like receptor 2-mediated modulation of growth and functions of regulatory T cells by oral streptococci.2013

    • Author(s)
      A. Saeki, T. Segawa, T. Abe, M. Sugiyama, T. Arimoto, H. Hara, A.Hasebe, M. Ohtani, N. Tanizume, M. Ohuchi, H. Kataoka, M. Kawanami, A. Yokoyama and K. Shibata.
    • Journal Title

      Mol Oral Microbiol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Toll-like receptor 2 - mediated modulation of growth and functions of regulatory T cells by oral streptococci2013

    • Author(s)
      A. Saeki, T. Segawa, T. Abe, M. Sugiyama, T. Arimoto, H. Hara, A.Hasebe, M. Ohtani, N. Tanizume, M. Ohuchi, H. Kataoka, M. Kawanami, A. Yokoyama and K. Shibata.
    • Journal Title

      molecular oral microbiology

      Volume: 未定 Pages: 1-14

    • DOI

      10.1111/omi.12023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352, KAKENHI-PROJECT-23792113, KAKENHI-PROJECT-24890006
  • [Journal Article] Mycoplasma Removal from Cell Culture Using Antimicrobial Photodynamic Therapy2013

    • Author(s)
      Akira Hasebe, Isao Ishikawa, Haque M. Shamsul, Makoto Ohtani, Taku Segawa, Ayumi Saeki, Naoho Tanizume, Manabu Oouchi, Yoshihide Okagami, Teruo Okano, Ken-ichiro Shibata
    • Journal Title

      Photomed Laser Surg

      Volume: 31 Pages: 125-131

    • DOI

      10.1089/pho.2012.3372

    • NAID

      120005372314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592692, KAKENHI-PROJECT-24890006
  • [Journal Article] Mycoplasma removal from cell culture using antimicrobial photodynamic therapy2013

    • Author(s)
      Akira Hasebe, Isao Ishikawa, Haque M. Shamsul, Makoto Ohtani, Taku Segawa, Ayumi Saeki, Naoho Tanizume, Manabu Oouchi, Yoshihide Okagami, Teruo Okano, and Ken-ichiro Shibata
    • Journal Title

      Photomedicine and Laser Surgery

      Volume: Vol. 31, No. 3

    • NAID

      120005372314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592692
  • [Journal Article] Involvement of suppressor of cytokine signaling-1-mediated degradation ofMyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signaling by the murine C-type lectinSIGNR1-mediated signaling2012

    • Author(s)
      M Ohtani , M Iyori , A Saeki, N Tanizume, T Into, A Hasebe , Y Totsuka and K Shibata
    • Journal Title

      Cell Microbiol

      Volume: 14(1) Pages: 40-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] Involvement of suppressor of cytokine signaling-1-mediated degradation of MyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signaling by the murine C-type lectin SIGNR1-mediated signaling2012

    • Author(s)
      M Ohtani, M Iyori, A Saeki, N Tanizume, T Into, A Hasebe, Y Totsuka, K Shibata
    • Journal Title

      Cellular Microbiology

      Volume: 14 Pages: 40-57

    • DOI

      10.1111/j.1462-5822.2011.01695.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] In vivo anti-and pro-tumour activities of the TLR2 ligandFSL-12011

    • Author(s)
      K Kiura, A Hasebe, A Saeki, T Segawa, F Okada, H M Shamsul, M Ohtani , T Into, N Inoue, M Wakita, K Shibata
    • Journal Title

      Immunobiology

      Volume: 216 Pages: 891-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] In vivo anti- and pro-tumour activities of the TLR2 ligand FSL-12011

    • Author(s)
      K Kiura, A Hasebe, A Saeki, T Segawa, F Okada, H M Shamsul, M Ohtani, T Into, N Inoue, M Wakita, K Shibata
    • Journal Title

      Immunobiology

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Journal Article] The TLR2 ligand FSL-1 is internalized via clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010

    • Author(s)
      HM.Shamsul, A.Hasebe, M.Iyori, M.Ohtani, K.Kiura, D.Zhang, Y Totsuka, K.Shibata
    • Journal Title

      Immunology (In press)

    • NAID

      120002414898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] The Toll-like receptor 2(TLR2)ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010

    • Author(s)
      Shamsul HM, Hasebe A, et al.
    • Journal Title

      Immunology (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791780
  • [Journal Article] The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2.2010

    • Author(s)
      Haque M.Shamsul, Akira Hasebe, Mitsuhiro Iyori, Makoto Ohtani, Kazuto Kiura, Diya Zhang, Yasunori Totsuka, Ken-ichiro Shibata.
    • Journal Title

      Immunology. 130

      Pages: 262-272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791780
  • [Journal Article] The TLR2 ligand FSL-1 is internalized via clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010

    • Author(s)
      HM Shamsul, A Hasebe, M Iyori, M Ohtani, K Kiura, D Zhang, Y Totsuka, K Shibata
    • Journal Title

      Immunology 130

      Pages: 262-272

    • NAID

      120002414898

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Reseveratrol modulates phagocytosis of bacteria through an NF-κB-dependent gene program.2008

    • Author(s)
      M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata*.
    • Journal Title

      Antimicrobial Agents Chemotherapy 52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] TLR2リガンドの取り込み機序2008

    • Author(s)
      長谷部晃
    • Journal Title

      臨床免疫・アレルギー科 50

      Pages: 162-166

    • Data Source
      KAKENHI-PROJECT-19791337
  • [Journal Article] A role of the Ca2+ binding site of DC-SIGN in the phagocytosis of E. coli.2008

    • Author(s)
      M Iyori, M Ohtani, A Hasebe, Y Totsuka, K Shibata
    • Journal Title

      Biochem. Biophy. Res. Comm 377(2)

      Pages: 367-372

    • NAID

      120002414904

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-κB-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, HM Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, K Shibata
    • Journal Title

      Antimicrob. Agents. Chemother 52(1)

      Pages: 121-127

    • NAID

      120002451617

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] Resveratrol modulatesphagocytosis of bacteria through an NF-・B-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, Haque M Shamsul,K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata
    • Journal Title

      Antimicrob Agents Chemother 52(1)

      Pages: 121-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] A role of the Ca^<2+> binding site ofDC-SIGN in the phagocytosis of E. coli.2008

    • Author(s)
      Mitsuhiro Iyori, Makoto Ohtani , Akira Hasebe, Yasunori Totsuka and K. Shibata
    • Journal Title

      Biochem. Biophy. Res. Comm. 377(2)

      Pages: 367-372

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-kB-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata*
    • Journal Title

      Antimicrobial Agents Chemotherapy 52

      Pages: 121-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] A role of the Ca^<2+> binding site of DC-SIGN in the phagocytosis of E. coli2008

    • Author(s)
      M Iyori, M Ohtani, A Hasebe, Y Totsuka and K Shibata
    • Journal Title

      Biochem. Biophy. Res. Comm. 377

      Pages: 367-372

    • NAID

      120002414904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Journal Article] TLR2 リガンドの取り込み機序2008

    • Author(s)
      長谷部 晃、Haque M. Shamsul、柴田 健一郎.
    • Journal Title

      臨床免疫・アレルギー科 50

      Pages: 162-166

    • Data Source
      KAKENHI-PROJECT-19791337
  • [Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-kB-dependent gene program2008

    • Author(s)
      M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata
    • Journal Title

      Antimicrobial Agents Chemotherapy 52

      Pages: 121-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] The diacylatedlipopeptide FSL-1 enhancesphagocytosis of bacteria bymacrophages through Toll-like receptor2-mediated signaling pathway.2007

    • Author(s)
      Mae M, Iyori M, Yasuda M, Shamsul H, Kataoka H, Hasebe A, Kiura K, TotsukaY, Shibata K.
    • Journal Title

      FEMS Immunol. Med. Microbiol 49

      Pages: 398-409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Journal Article] The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through Toll-like receptor 2-mediated signaling pathway2007

    • Author(s)
      M Mae, M Iyori, M Yasuda, HM Shamsul, H Kataoka, A Hasebe, K Kiura, Y Totsuka, K Shibata
    • Journal Title

      FEMS. Immunol. Med. Microbiol 49

      Pages: 398-409

    • NAID

      120002451616

    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] 口腔カンジダ症患者と非口腔カンジダ症患者由来の Candida albicansの病原性の比較2021

    • Author(s)
      大内 千里、長谷部 晃、北川 善政、坂田 健一郎
    • Organizer
      第86回 日本細菌学会北海道支部学術総会
    • Data Source
      KAKENHI-PROJECT-20K09917
  • [Presentation] Comparison of the properties of Candida albicans derived from patients with oral candidiasis and without oral candidiasis2021

    • Author(s)
      Chisato Oouchi, Akira Hasebe
    • Organizer
      第63回 歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K09917
  • [Presentation] Candida albicans oral ingestion affects intestinal microbial flora.2019

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-17K11606
  • [Presentation] 腸内細菌叢に及ぼすCandida albicans経口摂取の影響2018

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K11606
  • [Presentation] IL-1β production by dendritic cells and macrophages stimulated with Candida albicans2018

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第91回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-17K11606
  • [Presentation] IL-1beta production-inducing activity of Candida albicans toward dendritic cells and macrophages2017

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第90回日本細菌学会総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-26462775
  • [Presentation] 樹状細胞とマクロファージへのCandida albicansのIL-1β産生誘導2017

    • Author(s)
      長谷部 晃、佐伯 歩、柴田 健一郎
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K11606
  • [Presentation] 樹状細胞とマクロファージ細胞に対するCandida albicans のIL-1β 産生誘導の違い2016

    • Author(s)
      長谷部 晃、佐伯 歩、亀崎 良助、柴田 健一郎
    • Organizer
      第58回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-26462775
  • [Presentation] Recognition of oral streptococci by intracellular sensors, NODs and inflammasome2013

    • Author(s)
      Ayumi Saeki、Akira Hasebe、Futoshi Nakazawa, Ken-ichiro Shibata
    • Organizer
      日本細菌学会
    • Place of Presentation
      幕張メッセ国際会議場(千葉市)
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Recognition of oralstreptococci by intracellular sensorsNODs, and inflammasome2013

    • Author(s)
      佐伯歩、大谷誠、長谷部晃、中澤太、柴田健一郎
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ国際会議場,千葉
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌の抗腫瘍活性2012

    • Author(s)
      原 博志、佐伯 歩、長谷部 晃、柴田 健一郎.
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      奥羽大学(郡山)
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌の抗腫瘍活性2012

    • Author(s)
      原博志、佐伯歩、長谷部晃、柴田健一郎
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      奥羽大学,郡山
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌のパターン認識受容体による認識とインフラマゾームの活性化2012

    • Author(s)
      佐伯歩、杉山正博、瀬川卓、長谷部晃、北川善政、柴田健一郎
    • Organizer
      第79回日本細菌学会北海道支部学術総会.
    • Place of Presentation
      とかちプラザ,帯広
    • Year and Date
      2012-08-29
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 微生物由来リポタンパク質・リポペプチドの抗腫瘍活性2012

    • Author(s)
      原博志、佐伯歩、長谷部晃、柴田健一郎
    • Organizer
      第79回日本細菌学会北海道支部学術総会
    • Place of Presentation
      とかちプラザ,帯広
    • Year and Date
      2012-08-29
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] Roles of the src family kinase lck in Toll-like receptor 2 signaling triggered by stimulation with a diacylated lipopeptide FSL-1.2011

    • Author(s)
      Akira Hasebe, Naoho Tanizume, Makoto Ohtani, Ken-Ichiro Shibata.
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Data Source
      KAKENHI-PROJECT-23592692
  • [Presentation] 制御性T細胞(Treg)の免疫抑制活性に及ぼす口腔連鎖球菌の影響2011

    • Author(s)
      佐伯歩、瀬川卓、片岡嗣雄、長谷部晃、有本隆文、五十嵐武、川浪雅光、横山敦郎、柴田健一郎.
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場,岐阜
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 口腔連鎖球菌の生体からの排除におけるリポタンパク質の影響2011

    • Author(s)
      瀬川卓、長谷部晃、佐伯歩、片岡嗣雄、有本隆文、五十嵐武、横山敦郎、川浪雅光、柴田健一郎.
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場,岐阜
    • Data Source
      KAKENHI-PROJECT-22390352
  • [Presentation] 光線力学療法応用による培養細胞からのマイコプラズマ除去2010

    • Author(s)
      長谷部晃, et al.
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      タワーホール船堀(東京)
    • Data Source
      KAKENHI-PROJECT-21791780
  • [Presentation] The Toll-like receptor 2(TLR2)ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010

    • Author(s)
      Akira Hasebe, Ken-ichiro Shibata
    • Organizer
      第10回日韓国際微生物学シンポジウム
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21791780
  • [Presentation] マクロファージよるジアシルリポペプチドFSL-1の取り込みについて.2009

    • Author(s)
      長谷部 晃、伊従 光洋、柴田 健一郎.
    • Organizer
      第82回日本細菌学会総会.
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] How is the diacylated lipopeptide FSL-1processed after recognition by TLR2?2009

    • Author(s)
      MS Haque, A Hasebe, M Iyori, K Kiura, M Ohtani, K. Shibata
    • Organizer
      he 96th Annual Meeting of The American Association of Immunologists
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] Downregulation of the TLR2-mediated signal by the DC-SIGN ligand Man-LAM2009

    • Author(s)
      M Ohtani, A Hasebe, M Iyori, MS Haque, Y Totsuka, K Shibata
    • Organizer
      The 96th Annual Meeting of The American Association of Immunologists
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] マクロファージによるジアシルリポペプチドFSL-1の取り込みについて2009

    • Author(s)
      長谷部晃
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] Anti-and pro-tumor activities of the TLR2 ligand FSL-12009

    • Author(s)
      K Shibata, K Kiura, A Hasebe, M Iyori, MS Haque, M Ohtani
    • Organizer
      The 96th Annual Meeting of The American Association of Immunologists
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] マクロファージにおけるジアシルリポペプチドFSL-1 刺激により誘導される遺伝子発現の網羅的解析とFSL-1 の取り込み様式.2008

    • Author(s)
      長谷部 晃、モハメド シャムスル ハク、伊従 光洋、木浦 和人、大谷 誠、柴田 健一郎.
    • Organizer
      自然免疫の最前線-3 学会合同大会2008- 第73回日本インターフェロン・サイトカイン学会学術集会・第19回日本生体防御学会学術総会・第45回補体シンポジウム.
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] ジアシルリボペプチドFSL-1 による腫瘍増殖の抑制と促進2008

    • Author(s)
      木浦 和人、長谷部 晃、伊従 光洋、脇田 稔、安田 元昭、山本 恒之、井上 農夫男、柴田 健一郎
    • Organizer
      第75回日本細菌学会北海道支部学術総会(26-27)
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-08
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] Toll-like receptor 2とDC-SIGNシグナルのクロストーク2008

    • Author(s)
      大谷誠、伊従光洋、長谷部晃、木浦和人、戸塚靖則、柴田健一郎
    • Organizer
      日本マイコプラズマ学会第35回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] ジアシルリポペプチドFSL-1 による制御性T細胞の増殖と腫瘍免疫応答の抑制2008

    • Author(s)
      木浦 和人、長谷部 晃、大谷 誠、伊従 光洋、柴田 健一郎
    • Organizer
      第76回日本細菌学会北海道支部学術総会(抄録集 30)
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-06
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] マクロファージにおけるジアシルリポペプチドFSL-1 刺激により誘導される遺伝子発現の網羅的解析とFSL-1取り込み様式について.2008

    • Author(s)
      長谷部 晃、シャムスル ハク、伊従光洋、木浦 和人、大谷 誠、柴田 健一郎.
    • Organizer
      第50 回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] マクロファージにおけるジアシルリポペプチドFSL-1 刺激による遺伝子発現の網羅的解析とFSL-1 の取り込み様式.2008

    • Author(s)
      長谷部 晃、モハメド シャムスル ハク、伊従 光洋、木浦 和人、大谷 誠、柴田 健一郎.
    • Organizer
      日本マイコプラズマ学会第35 回学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] ジアシルリポペプチドFSL-1による制御性T細胞の増殖と腫瘍免疫応答の抑制2008

    • Author(s)
      木浦和人、長谷部晃、柴田健一郎
    • Organizer
      日本マイコプラズマ学会第35回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-31
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] ジアシルリポペプチドFSL-1 による刺激で誘導されるマクロファージの遺伝子発現の網羅的解析とFSL-1 の取り込み様式.2008

    • Author(s)
      長谷部 晃、モハメド シャムスル ハク、伊従 光洋、木浦 和人、大谷 誠、柴田 健一郎.
    • Organizer
      第76 回日本細菌学会北海道支部学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-09-06
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] The uptake manner of the diacylated lipopeptide FSL-1 by macrophages2008

    • Author(s)
      Hasebe A., Shamsul H. M., Iyori M., Kiura K., Ohtani M.,Shibata K.
    • Organizer
      Regulation in Innate Immunity - from Recognition Molecules to Antimicrobial Peptides.
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] Toll-like receptor 2シグナルに及ぼすDC-SIGNシグナルの影響(優秀ポスター賞受賞)2008

    • Author(s)
      大谷誠、伊従光洋、長谷部晃、木浦和人、戸塚靖則、柴田健一郎
    • Organizer
      第50回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-24
    • Data Source
      KAKENHI-PROJECT-19390477
  • [Presentation] ジアシルリポペプチドFSL-1 による制御性T細胞の増殖と腫瘍免疫応答の抑制2008

    • Author(s)
      木浦 和人、長谷部 晃、柴田 健一郎
    • Organizer
      日本マイコプラズマ学会第35回学術集会(講演要旨集)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] ジアシルリポペプチドFSL-1 刺激により誘導されるマクロファージの遺伝子発現の網羅的解析とFSL-1 取り込み様式.2008

    • Author(s)
      長谷部 晃、伊従 光洋、木浦 和人、大谷 誠、柴田 健一郎.
    • Organizer
      第38 回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] マクロファージのジアシルリポペプチドFSL-1刺激による遺伝子発現の網羅的解析とFSL-1の取り込み様式について.2007

    • Author(s)
      長谷部 晃、伊従 光洋、安田 元昭、木浦 和人、柴田 健一郎.
    • Organizer
      第37 回日本免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] ジアシルリポペプチドFSL-1 の腫瘍増殖に及ぼす影響2007

    • Author(s)
      木浦 和人、長谷部 晃、伊従 光洋、安田 元昭、大谷 誠、柴田 健一郎
    • Organizer
      第37回日本免疫学会総会・学術集会(日本免疫学会総会・学術集会記録 第37 巻 : 217)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] マクロファージにおけるジアシルリボペプチドFSL-1 刺激による遺伝子発現の網羅的解析ならびにFSL-1 の取り込み様式について.2007

    • Author(s)
      長谷部 晃、モハメド シャムスル ハク、伊従 光洋、安田 元昭、木浦 和人、柴田 健一郎.
    • Organizer
      第75回日本細菌学会北海道支部学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-08
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] マクロファージにおけるFSL-1 の取り込み様式と遺伝子発現の網羅的解析.2007

    • Author(s)
      長谷部 晃、ハク モハメド、伊従 光洋、安田 元昭、木浦 和人、柴田 健一郎.
    • Organizer
      第49 回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] マクロファージのジアシルリポペプチドFSL-1刺激による遺伝子発現の網羅的解析とFSL-1の取り込み様式について2007

    • Author(s)
      長谷部 晃
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      東京グランドプリンスホテル新高輪
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-19791337
  • [Presentation] マイコプラズマ由来ジアシルリポペプチド FSL-1 の抗腫瘍活性2007

    • Author(s)
      木浦 和人、安田 元昭、長谷部 晃、伊従 光洋、脇田 稔、山本 恒之、井上 農夫男、柴田 健一郎
    • Organizer
      日本マイコプラズマ学会第34回学術集会(講演予稿集)
    • Place of Presentation
      和歌山
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] マイコプラズマ由来ジアシルリボペプチドFSL1 の腫瘍増殖に及ぼす影響2007

    • Author(s)
      木浦 和人、安田 元昭、長谷部 晃、伊従 光洋、脇田 稔、山本 恒之、井上 農夫男、柴田 健一郎
    • Organizer
      第49回歯科基礎医学会学術大会・総会(Journal of Oral Biosciences 49 Suppl : 131)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19592166
  • [Presentation] Candida albicansによるマクロファージと樹状細胞へのIL-1β産生誘導の違い

    • Author(s)
      長谷部 晃、佐伯 歩、杉山 正博、柴田 健一郎
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26462775
  • 1.  SHIBATA Kenichiro (50145265)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 42 results
  • 2.  SAEKI AYUMI (70638345)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  箕輪 和行 (30209845)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  亀田 浩之 (70829887)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Tsuguo (10064362)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  木浦 和人 (50435947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 7.  大廣 洋一 (40301915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  北村 哲也 (00451451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  樋田 京子 (40399952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  竹内 明子 (00867179)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  的場 光太郎 (00466450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  兵頭 秀樹 (30306154)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  長谷 由理 (20626121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  舩橋 誠 (80221555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  大賀 則孝 (40548202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  北川 善政 (00224957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  坂田 健一郎 (10826051)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  山村 凌大 (40880000)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  佐藤 淳 (60319069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  園下 将大 (80511857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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