Hasebe Akira 長谷部晃

… Alternative Names

Researcher Number	90281815
Other IDs
External Links
Affiliation (Current)	2021: 北海道大学, 歯学研究院, 教授
Affiliation (based on the past Project Information) *help	2019 – 2020: 北海道大学, 歯学研究院, 教授 2017 – 2018: 北海道大学, 歯学研究院, 助教 2016: 北海道大学, 歯学研究科, 助教 2011 – 2015: 北海道大学, 歯学研究科(研究院), 助教 2007 – 2012: Hokkaido University, 大学院・歯学研究科, 助教 … More
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) / Basic Section 57080:Social dentistry-related / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator TLR2 / 口腔カンジダ症 / リポタンパク質 / 口腔細菌学 / マイコプラズマ / FSL-1 / Candida albicans / 腸炎 / IL-6 / Mycoplasma salivarium … More Except Principal Investigator 炎症 / TLR2 / 制御性T細胞 / リポタンパク質 / Mycoplasma salivarium / ICAM-1 / 免疫 / 感染 / FSL-1 / DC-SIGN / XS106細胞 / リポアラビノマンナン / MDDC / Man_9(GLcNAc)_2 / 微生物由来リポペプチドFSL-1 / 自然免疫 / アジュバント / 坑腫瘍免疫 / 抗体依存性細胞傷害活性 / ガン / 抗腫瘍活性 / 口腔細菌 / 口腔レンサ球菌 / B16メラノーマ / NK細胞 / Toll-like receptor / リポペプチドFSL-1 / 腫瘍 / 歯肉線維芽細胞 / リポペプチド / 口腔微生物 / 接着因子 / gingival fibroblasts / lipoprotein / lipopeptide / 歯周病原性菌 / 脳血管障害 / 死後画像 / P.gingivalis / 口腔がん / 口腔常在菌 / リンパ節転移メカニズム / 転移 / 悪性化 / 予後予測マーカー Less

How oral candidiasis can exacerbate colitis?Principal InvestigatorOngoing
- Principal Investigator
  
  長谷部晃
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hokkaido University
全身主要血管壁内における歯周病原性菌の存在分布ー脳血管障害による死亡例をもとにOngoing
- Principal Investigator
  
  竹内明子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Hokkaido University
Association between oral bacteria and oral cancer metastasisOngoing
- Principal Investigator
  
  大廣洋一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hokkaido University
Exploring the systemic effect on intestinal dysbiosis induced by oral Candida albicansPrincipal Investigator
- Principal Investigator
  
  Hasebe Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
Can oral Candida albicans induce C. albicans specific colonic regulatory T cells?Principal Investigator
- Principal Investigator
  
  Hasebe Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
Development of a method to remove mycoplasmas from the contaminated cell cultures using antimicrobial photodynamic therapyPrincipal Investigator
- Principal Investigator
  
  HASEBE Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
Activation of regulatory T cells by oral inhabitant bacteria and relationship of their existence and growth of cancer
- Principal Investigator
  
  SHIBATA Ken-ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hokkaido University
The roles of bacterial lipoproteins on bacterial invasion and on intracellular trafficking in host cellsPrincipal Investigator
- Principal Investigator
  
  HASEBE Akira
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
A crosstalk between Toll-like receptor and C-type lectin
- Principal Investigator
  
  SHIBATA Kenichiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hokkaido University
Effects of microbial lipoproteins and lipopeptides on the growthof tumor
- Principal Investigator
  
  木浦和人
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hokkaido University
Studies on molecular mechanism of phagocytosis in innate immune systemPrincipal Investigator
- Principal Investigator
  
  HASEBE Akira
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
歯周病克服への新たなアプローチを目指して〜歯周病原細菌由来リポタンパク質の研究Principal Investigator
- Principal Investigator
  
  長谷部晃
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
歯肉線維芽細胞にIL-6とIL-8を誘導するマイコプラズマ由来物質の精製と性状Principal Investigator
- Principal Investigator
  
  長谷部晃
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hokkaido University
Physiological and pathological roles of adhesion molecules expressed on gingival fibroblasts in response to oral microbes
- Principal Investigator
  
  SHIBATA Ken-ichiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  HOKKAIDO UNIVERSITY

All 2019 2018 2017 2016 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Differences in interleukin-1β release-inducing activity of Candida albicans toward dendritic cells and macrophages2018
- Author(s)
  Hasebe Akira、Saeki Ayumi、Yoshida Yasuhiro、Shibata Ken-ichiro
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 93 Pages: 115-125
- DOI
  10.1016/j.archoralbio.2018.06.004
- Data Source
  KAKENHI-PROJECT-17K11606
[Journal Article] Toll-like receptor 2-mediated modulation of growth and functions of regulatory T cells by oral streptococci.2013
- Author(s)
  A. Saeki, T. Segawa, T. Abe, M. Sugiyama, T. Arimoto, H. Hara, A.Hasebe, M. Ohtani, N. Tanizume, M. Ohuchi, H. Kataoka, M. Kawanami, A. Yokoyama and K. Shibata.
- Journal Title
  
  Mol Oral Microbiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352
[Journal Article] Mycoplasma Removal from Cell Culture Using Antimicrobial Photodynamic Therapy2013
- Author(s)
  A Hasebe, I Ishikawa, H M Shamsul, M Ohtani, T Segawa, A Saeki, N Tanizume, M Oouchi, Y Okagami, T Okano, and K Shibata
- Journal Title
  
  Photomed Laser Surg
  
  Volume: 31 Pages: 1-7
- NAID
  120005372314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352
[Journal Article] Mycoplasma removal from cell culture using antimicrobial photodynamic therapy2013
- Author(s)
  Akira Hasebe, Isao Ishikawa, Haque M. Shamsul, Makoto Ohtani, Taku Segawa, Ayumi Saeki, Naoho Tanizume, Manabu Oouchi, Yoshihide Okagami, Teruo Okano, Ken-ichiro Shibata
- Journal Title
  
  Photomed Laser Surg
  
  Volume: 31 Pages: 125-131
- DOI
  10.1089/pho.2012.3372
- NAID
  120005372314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592692, KAKENHI-PROJECT-24890006
[Journal Article] Toll-like receptor 2 - mediated modulation of growth and functions of regulatory T cells by oral streptococci2013
- Author(s)
  A. Saeki, T. Segawa, T. Abe, M. Sugiyama, T. Arimoto, H. Hara, A.Hasebe, M. Ohtani, N. Tanizume, M. Ohuchi, H. Kataoka, M. Kawanami, A. Yokoyama and K. Shibata.
- Journal Title
  
  molecular oral microbiology
  
  Volume: 未定 Pages: 1-14
- DOI
  10.1111/omi.12023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352, KAKENHI-PROJECT-23792113, KAKENHI-PROJECT-24890006
[Journal Article] Mycoplasma removal from cell culture using antimicrobial photodynamic therapy2013
- Author(s)
  Akira Hasebe, Isao Ishikawa, Haque M. Shamsul, Makoto Ohtani, Taku Segawa, Ayumi Saeki, Naoho Tanizume, Manabu Oouchi, Yoshihide Okagami, Teruo Okano, and Ken-ichiro Shibata
- Journal Title
  
  Photomedicine and Laser Surgery
  
  Volume: Vol. 31, No. 3
- NAID
  120005372314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592692
[Journal Article] Involvement of suppressor of cytokine signaling-1-mediated degradation ofMyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signaling by the murine C-type lectinSIGNR1-mediated signaling2012
- Author(s)
  M Ohtani , M Iyori , A Saeki, N Tanizume, T Into, A Hasebe , Y Totsuka and K Shibata
- Journal Title
  
  Cell Microbiol
  
  Volume: 14(1) Pages: 40-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352
[Journal Article] Involvement of suppressor of cytokine signaling-1-mediated degradation of MyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signaling by the murine C-type lectin SIGNR1-mediated signaling2012
- Author(s)
  M Ohtani, M Iyori, A Saeki, N Tanizume, T Into, A Hasebe, Y Totsuka, K Shibata
- Journal Title
  
  Cellular Microbiology
  
  Volume: 14 Pages: 40-57
- DOI
  10.1111/j.1462-5822.2011.01695.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352
[Journal Article] In vivo anti-and pro-tumour activities of the TLR2 ligandFSL-12011
- Author(s)
  K Kiura, A Hasebe, A Saeki, T Segawa, F Okada, H M Shamsul, M Ohtani , T Into, N Inoue, M Wakita, K Shibata
- Journal Title
  
  Immunobiology
  
  Volume: 216 Pages: 891-900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352
[Journal Article] In vivo anti- and pro-tumour activities of the TLR2 ligand FSL-12011
- Author(s)
  K Kiura, A Hasebe, A Saeki, T Segawa, F Okada, H M Shamsul, M Ohtani, T Into, N Inoue, M Wakita, K Shibata
- Journal Title
  
  Immunobiology
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390352
[Journal Article] The TLR2 ligand FSL-1 is internalized via clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010
- Author(s)
  HM Shamsul, A Hasebe, M Iyori, M Ohtani, K Kiura, D Zhang, Y Totsuka, K Shibata
- Journal Title
  
  Immunology 130
  
  Pages: 262-272
- NAID
  120002414898
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] The Toll-like receptor 2(TLR2)ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010
- Author(s)
  Shamsul HM, Hasebe A, et al.
- Journal Title
  
  Immunology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791780
[Journal Article] The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2.2010
- Author(s)
  Haque M.Shamsul, Akira Hasebe, Mitsuhiro Iyori, Makoto Ohtani, Kazuto Kiura, Diya Zhang, Yasunori Totsuka, Ken-ichiro Shibata.
- Journal Title
  
  Immunology. 130
  
  Pages: 262-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791780
[Journal Article] The TLR2 ligand FSL-1 is internalized via clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010
- Author(s)
  HM.Shamsul, A.Hasebe, M.Iyori, M.Ohtani, K.Kiura, D.Zhang, Y Totsuka, K.Shibata
- Journal Title
  
  Immunology (In press)
- NAID
  120002414898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] A role of the Ca2+ binding site of DC-SIGN in the phagocytosis of E. coli.2008
- Author(s)
  M Iyori, M Ohtani, A Hasebe, Y Totsuka, K Shibata
- Journal Title
  
  Biochem. Biophy. Res. Comm 377(2)
  
  Pages: 367-372
- NAID
  120002414904
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-kB-dependent gene program2008
- Author(s)
  M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata*
- Journal Title
  
  Antimicrobial Agents Chemotherapy 52
  
  Pages: 121-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-kB-dependent gene program2008
- Author(s)
  M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata
- Journal Title
  
  Antimicrobial Agents Chemotherapy 52
  
  Pages: 121-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592166
[Journal Article] TLR2 リガンドの取り込み機序2008
- Author(s)
  長谷部晃、Haque M. Shamsul、柴田健一郎.
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 162-166
- Data Source
  KAKENHI-PROJECT-19791337
[Journal Article] Reseveratrol modulates phagocytosis of bacteria through an NF-κB-dependent gene program.2008
- Author(s)
  M Iyori, H Kataoka, H M Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata*.
- Journal Title
  
  Antimicrobial Agents Chemotherapy 52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] Resveratrol modulatesphagocytosis of bacteria through an NF-・B-dependent gene program2008
- Author(s)
  M Iyori, H Kataoka, Haque M Shamsul,K Kiura, T Nakata, A Hasebe, M Yasuda, and K Shibata
- Journal Title
  
  Antimicrob Agents Chemother 52(1)
  
  Pages: 121-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592166
[Journal Article] A role of the Ca^<2+> binding site of DC-SIGN in the phagocytosis of E. coli2008
- Author(s)
  M Iyori, M Ohtani, A Hasebe, Y Totsuka and K Shibata
- Journal Title
  
  Biochem. Biophy. Res. Comm. 377
  
  Pages: 367-372
- NAID
  120002414904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] TLR2リガンドの取り込み機序2008
- Author(s)
  長谷部晃
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 162-166
- Data Source
  KAKENHI-PROJECT-19791337
[Journal Article] Resveratrol modulates phagocytosis of bacteria through an NF-κB-dependent gene program2008
- Author(s)
  M Iyori, H Kataoka, HM Shamsul, K Kiura, T Nakata, A Hasebe, M Yasuda, K Shibata
- Journal Title
  
  Antimicrob. Agents. Chemother 52(1)
  
  Pages: 121-127
- NAID
  120002451617
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] A role of the Ca^<2+> binding site ofDC-SIGN in the phagocytosis of E. coli.2008
- Author(s)
  Mitsuhiro Iyori, Makoto Ohtani , Akira Hasebe, Yasunori Totsuka and K. Shibata
- Journal Title
  
  Biochem. Biophy. Res. Comm. 377(2)
  
  Pages: 367-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592166
[Journal Article] The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through Toll-like receptor 2-mediated signaling pathway2007
- Author(s)
  M Mae, M Iyori, M Yasuda, HM Shamsul, H Kataoka, A Hasebe, K Kiura, Y Totsuka, K Shibata
- Journal Title
  
  FEMS. Immunol. Med. Microbiol 49
  
  Pages: 398-409
- NAID
  120002451616
- Data Source
  KAKENHI-PROJECT-19390477
[Journal Article] The diacylatedlipopeptide FSL-1 enhancesphagocytosis of bacteria bymacrophages through Toll-like receptor2-mediated signaling pathway.2007
- Author(s)
  Mae M, Iyori M, Yasuda M, Shamsul H, Kataoka H, Hasebe A, Kiura K, TotsukaY, Shibata K.
- Journal Title
  
  FEMS Immunol. Med. Microbiol 49
  
  Pages: 398-409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] Candida albicans oral ingestion affects intestinal microbial flora．2019
- Author(s)
  長谷部　晃、佐伯　歩、柴田　健一郎
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K11606
[Presentation] IL-1β production by dendritic cells and macrophages stimulated with Candida albicans2018
- Author(s)
  長谷部　晃、佐伯　歩、柴田　健一郎
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K11606
[Presentation] 腸内細菌叢に及ぼすCandida albicans経口摂取の影響2018
- Author(s)
  長谷部　晃、佐伯　歩、柴田　健一郎
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11606
[Presentation] IL-1beta production-inducing activity of Candida albicans toward dendritic cells and macrophages2017
- Author(s)
  長谷部　晃、佐伯　歩、柴田　健一郎
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-26462775
[Presentation] 樹状細胞とマクロファージへのCandida albicansのIL-1β産生誘導2017
- Author(s)
  長谷部　晃、佐伯　歩、柴田　健一郎
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11606
[Presentation] 樹状細胞とマクロファージ細胞に対するCandida albicans のIL-1β 産生誘導の違い2016
- Author(s)
  長谷部　晃、佐伯　歩、亀崎　良助、柴田　健一郎
- Organizer
  第58回歯科基礎医学会学術大会・総会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26462775
[Presentation] Recognition of oralstreptococci by intracellular sensorsNODs, and inflammasome2013
- Author(s)
  佐伯歩、大谷誠、長谷部晃、中澤太、柴田健一郎
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ国際会議場,千葉
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] Recognition of oral streptococci by intracellular sensors, NODs and inflammasome2013
- Author(s)
  Ayumi Saeki、Akira Hasebe、Futoshi Nakazawa, Ken-ichiro Shibata
- Organizer
  日本細菌学会
- Place of Presentation
  幕張メッセ国際会議場（千葉市）
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] 口腔連鎖球菌の抗腫瘍活性2012
- Author(s)
  原博志、佐伯歩、長谷部晃、柴田健一郎
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  奥羽大学,郡山
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] 口腔連鎖球菌の抗腫瘍活性2012
- Author(s)
  原　博志、佐伯　歩、長谷部　晃、柴田　健一郎．
- Organizer
  歯科基礎医学会
- Place of Presentation
  奥羽大学（郡山）
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] 微生物由来リポタンパク質・リポペプチドの抗腫瘍活性2012
- Author(s)
  原博志、佐伯歩、長谷部晃、柴田健一郎
- Organizer
  第79回日本細菌学会北海道支部学術総会
- Place of Presentation
  とかちプラザ,帯広
- Year and Date
  2012-08-29
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] 口腔連鎖球菌のパターン認識受容体による認識とインフラマゾームの活性化2012
- Author(s)
  佐伯歩、杉山正博、瀬川卓、長谷部晃、北川善政、柴田健一郎
- Organizer
  第79回日本細菌学会北海道支部学術総会.
- Place of Presentation
  とかちプラザ,帯広
- Year and Date
  2012-08-29
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] 制御性T細胞(Treg)の免疫抑制活性に及ぼす口腔連鎖球菌の影響2011
- Author(s)
  佐伯歩、瀬川卓、片岡嗣雄、長谷部晃、有本隆文、五十嵐武、川浪雅光、横山敦郎、柴田健一郎.
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  長良川国際会議場,岐阜
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] 口腔連鎖球菌の生体からの排除におけるリポタンパク質の影響2011
- Author(s)
  瀬川卓、長谷部晃、佐伯歩、片岡嗣雄、有本隆文、五十嵐武、横山敦郎、川浪雅光、柴田健一郎.
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  長良川国際会議場,岐阜
- Data Source
  KAKENHI-PROJECT-22390352
[Presentation] Roles of the src family kinase lck in Toll-like receptor 2 signaling triggered by stimulation with a diacylated lipopeptide FSL-1.2011
- Author(s)
  Akira Hasebe, Naoho Tanizume, Makoto Ohtani, Ken-Ichiro Shibata.
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Data Source
  KAKENHI-PROJECT-23592692
[Presentation] The Toll-like receptor 2(TLR2)ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR22010
- Author(s)
  Akira Hasebe, Ken-ichiro Shibata
- Organizer
  第10回日韓国際微生物学シンポジウム
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21791780
[Presentation] 光線力学療法応用による培養細胞からのマイコプラズマ除去2010
- Author(s)
  長谷部晃, et al.
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-21791780
[Presentation] Anti-and pro-tumor activities of the TLR2 ligand FSL-12009
- Author(s)
  K Shibata, K Kiura, A Hasebe, M Iyori, MS Haque, M Ohtani
- Organizer
  The 96th Annual Meeting of The American Association of Immunologists
- Place of Presentation
  Seattle, Washington, USA
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-19390477
[Presentation] マクロファージによるジアシルリポペプチドFSL-1の取り込みについて2009
- Author(s)
  長谷部晃
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] How is the diacylated lipopeptide FSL-1processed after recognition by TLR2?2009
- Author(s)
  MS Haque, A Hasebe, M Iyori, K Kiura, M Ohtani, K. Shibata
- Organizer
  he 96th Annual Meeting of The American Association of Immunologists
- Place of Presentation
  Seattle, Washington, USA
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-19390477
[Presentation] マクロファージよるジアシルリポペプチドFSL-1の取り込みについて.2009
- Author(s)
  長谷部晃、伊従光洋、柴田健一郎.
- Organizer
  第82回日本細菌学会総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] Downregulation of the TLR2-mediated signal by the DC-SIGN ligand Man-LAM2009
- Author(s)
  M Ohtani, A Hasebe, M Iyori, MS Haque, Y Totsuka, K Shibata
- Organizer
  The 96th Annual Meeting of The American Association of Immunologists
- Place of Presentation
  Seattle, Washington, USA
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-19390477
[Presentation] ジアシルリポペプチドFSL-1 刺激により誘導されるマクロファージの遺伝子発現の網羅的解析とFSL-1 取り込み様式.2008
- Author(s)
  長谷部晃、伊従光洋、木浦和人、大谷誠、柴田健一郎.
- Organizer
  第38 回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] The uptake manner of the diacylated lipopeptide FSL-1 by macrophages2008
- Author(s)
  Hasebe A., Shamsul H. M., Iyori M., Kiura K., Ohtani M.,Shibata K.
- Organizer
  Regulation in Innate Immunity - from Recognition Molecules to Antimicrobial Peptides.
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] Toll-like receptor 2シグナルに及ぼすDC-SIGNシグナルの影響(優秀ポスター賞受賞)2008
- Author(s)
  大谷誠、伊従光洋、長谷部晃、木浦和人、戸塚靖則、柴田健一郎
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19390477
[Presentation] ジアシルリポペプチドFSL-1による制御性T細胞の増殖と腫瘍免疫応答の抑制2008
- Author(s)
  木浦和人、長谷部晃、柴田健一郎
- Organizer
  日本マイコプラズマ学会第35回学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-19390477
[Presentation] マクロファージにおけるジアシルリポペプチドFSL-1 刺激により誘導される遺伝子発現の網羅的解析とFSL-1 の取り込み様式.2008
- Author(s)
  長谷部晃、モハメドシャムスルハク、伊従光洋、木浦和人、大谷誠、柴田健一郎.
- Organizer
  自然免疫の最前線-3 学会合同大会2008- 第73回日本インターフェロン・サイトカイン学会学術集会・第19回日本生体防御学会学術総会・第45回補体シンポジウム.
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] Toll-like receptor 2とDC-SIGNシグナルのクロストーク2008
- Author(s)
  大谷誠、伊従光洋、長谷部晃、木浦和人、戸塚靖則、柴田健一郎
- Organizer
  日本マイコプラズマ学会第35回学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19390477
[Presentation] ジアシルリポペプチドFSL-1 による制御性T細胞の増殖と腫瘍免疫応答の抑制2008
- Author(s)
  木浦和人、長谷部晃、大谷誠、伊従光洋、柴田健一郎
- Organizer
  第76回日本細菌学会北海道支部学術総会(抄録集 30)
- Place of Presentation
  札幌
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] ジアシルリボペプチドFSL-1 による腫瘍増殖の抑制と促進2008
- Author(s)
  木浦和人、長谷部晃、伊従光洋、脇田稔、安田元昭、山本恒之、井上農夫男、柴田健一郎
- Organizer
  第75回日本細菌学会北海道支部学術総会(26-27)
- Place of Presentation
  札幌
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] ジアシルリポペプチドFSL-1 による刺激で誘導されるマクロファージの遺伝子発現の網羅的解析とFSL-1 の取り込み様式.2008
- Author(s)
  長谷部晃、モハメドシャムスルハク、伊従光洋、木浦和人、大谷誠、柴田健一郎.
- Organizer
  第76 回日本細菌学会北海道支部学術総会
- Place of Presentation
  札幌
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] マクロファージにおけるジアシルリポペプチドFSL-1 刺激による遺伝子発現の網羅的解析とFSL-1 の取り込み様式.2008
- Author(s)
  長谷部晃、モハメドシャムスルハク、伊従光洋、木浦和人、大谷誠、柴田健一郎.
- Organizer
  日本マイコプラズマ学会第35 回学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] マクロファージにおけるジアシルリポペプチドFSL-1 刺激により誘導される遺伝子発現の網羅的解析とFSL-1取り込み様式について.2008
- Author(s)
  長谷部晃、シャムスルハク、伊従光洋、木浦和人、大谷誠、柴田健一郎.
- Organizer
  第50 回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] ジアシルリポペプチドFSL-1 による制御性T細胞の増殖と腫瘍免疫応答の抑制2008
- Author(s)
  木浦和人、長谷部晃、柴田健一郎
- Organizer
  日本マイコプラズマ学会第35回学術集会(講演要旨集)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] マイコプラズマ由来ジアシルリポペプチド FSL-1 の抗腫瘍活性2007
- Author(s)
  木浦和人、安田元昭、長谷部晃、伊従光洋、脇田稔、山本恒之、井上農夫男、柴田健一郎
- Organizer
  日本マイコプラズマ学会第34回学術集会(講演予稿集)
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] マクロファージのジアシルリポペプチドFSL-1刺激による遺伝子発現の網羅的解析とFSL-1の取り込み様式について.2007
- Author(s)
  長谷部晃、伊従光洋、安田元昭、木浦和人、柴田健一郎.
- Organizer
  第37 回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] マクロファージにおけるジアシルリボペプチドFSL-1 刺激による遺伝子発現の網羅的解析ならびにFSL-1 の取り込み様式について.2007
- Author(s)
  長谷部晃、モハメドシャムスルハク、伊従光洋、安田元昭、木浦和人、柴田健一郎.
- Organizer
  第75回日本細菌学会北海道支部学術総会
- Place of Presentation
  札幌
- Year and Date
  2007-09-08
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] マクロファージにおけるFSL-1 の取り込み様式と遺伝子発現の網羅的解析.2007
- Author(s)
  長谷部晃、ハクモハメド、伊従光洋、安田元昭、木浦和人、柴田健一郎.
- Organizer
  第49 回歯科基礎医学会学術大会・総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] マクロファージのジアシルリポペプチドFSL-1刺激による遺伝子発現の網羅的解析とFSL-1の取り込み様式について2007
- Author(s)
  長谷部晃
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京グランドプリンスホテル新高輪
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19791337
[Presentation] マイコプラズマ由来ジアシルリボペプチドFSL1 の腫瘍増殖に及ぼす影響2007
- Author(s)
  木浦和人、安田元昭、長谷部晃、伊従光洋、脇田稔、山本恒之、井上農夫男、柴田健一郎
- Organizer
  第49回歯科基礎医学会学術大会・総会(Journal of Oral Biosciences 49 Suppl : 131)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] ジアシルリポペプチドFSL-1 の腫瘍増殖に及ぼす影響2007
- Author(s)
  木浦和人、長谷部晃、伊従光洋、安田元昭、大谷誠、柴田健一郎
- Organizer
  第37回日本免疫学会総会・学術集会(日本免疫学会総会・学術集会記録第37 巻 : 217)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19592166
[Presentation] Candida albicansによるマクロファージと樹状細胞へのIL-1β産生誘導の違い
- Author(s)
  長谷部　晃、佐伯　歩、杉山　正博、柴田　健一郎
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462775

1. SHIBATA Kenichiro (50145265)

# of Collaborated Projects: 5 results

# of Collaborated Products: 42 results
2. SAEKI AYUMI (70638345)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. WATANABE Tsuguo (10064362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 木浦和人 (50435947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 竹内明子 (00867179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 的場光太郎 (00466450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 箕輪和行 (30209845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 兵頭秀樹 (30306154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 亀田浩之 (70829887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大廣洋一 (40301915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 北村哲也 (00451451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 樋田京子 (40399952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hasebe Akira 長谷部 晃

HASEBE Akira 長谷部 晃

長谷部 晃 ハセベ アキラ

Research Projects

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How oral candidiasis can exacerbate colitis?Principal InvestigatorOngoing

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全身主要血管壁内における歯周病原性菌の存在分布ー脳血管障害による死亡例をもとにOngoing

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Association between oral bacteria and oral cancer metastasisOngoing

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Exploring the systemic effect on intestinal dysbiosis induced by oral Candida albicansPrincipal Investigator

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Can oral Candida albicans induce C. albicans specific colonic regulatory T cells?Principal Investigator

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Development of a method to remove mycoplasmas from the contaminated cell cultures using antimicrobial photodynamic therapyPrincipal Investigator

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Activation of regulatory T cells by oral inhabitant bacteria and relationship of their existence and growth of cancer

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The roles of bacterial lipoproteins on bacterial invasion and on intracellular trafficking in host cellsPrincipal Investigator

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A crosstalk between Toll-like receptor and C-type lectin

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Effects of microbial lipoproteins and lipopeptides on the growthof tumor

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Studies on molecular mechanism of phagocytosis in innate immune systemPrincipal Investigator

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歯周病克服への新たなアプローチを目指して〜歯周病原細菌由来リポタンパク質の研究Principal Investigator

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歯肉線維芽細胞にIL-6とIL-8を誘導するマイコプラズマ由来物質の精製と性状Principal Investigator

Principal Investigator

Hasebe Akira 長谷部晃

HASEBE Akira 長谷部晃

長谷部晃ハセベアキラ