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YAMAMOTO Naomasa  山本 正雅

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… Alternative Names

山本 正雄  ヤマモト ナオマサ

山本 正雅  ヤマモト ナオマサ

山本 正雅雄

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Researcher Number 50150884
External Links
Affiliation (based on the past Project Information) *help 2009 – 2010: Ohu University, 薬学部, 准教授
2006: The Tokyo Metropolitan Institute of Medical Science, Chief Researcher, 東京都臨床医学総合研究所, 主任研究員
2005 – 2006: 奥羽大学, 薬学部, 助教授
2003 – 2005: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員
2003 – 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 … More
1998: 財団法人 東京都臨床医学総合研究所, 循環器病研究部門, 研究員
1998: Tokyo Metro.Institute of Med.Science, Researcher, 循環器病, 研究員
1997: (財)東京都臨床医学総合研究所, 循環器病, 研究員
1995: 財団法人東京都臨床医学総合研究所, 循環器病研究部門, 研究員
1993: 財団法人 東京都臨床医学総合研究所, 循環器病研究部門, 研究員
1992: (財)東京都臨床医学総合研究所, 循環器病研究部門, 研究員
1992: The Tokyo Metropolitan Institute of Medical Science, Department of Cardiovascular Research, Scientist, 循看器病研究部門, 研究員
1991: Tokyo Metropolitan Institute of Medical Science., Dept. of Cardiovas. Res., Rese, 循環器病研究部門, 研究員
1991: 東京都臨床医学総合研究所, 循環器病研部門, 研究員
1986 – 1987: 東京都臨床医学総合研究所, 循環器病研究部, 研究員 Less
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Except Principal Investigator
Hematology / Cell biology
Keywords
Principal Investigator
血小板 / IX / GPIb / Bernard-Soulier syndrome / PCR / ヒト抗体 / SPYMEG / V複合体 / 血小板凝集 / モノクローナル抗体 … More / GPIV / Signal trunsduction / BSS Tokyo / V complex / GPlb / ristocetin-induced agglutination / ATP-release / 14-3-3 / GPlbalpha / BSS Tokyo II. / リストセチ凝集 / シグナル伝達 / BSS Tokyo II / リストセチン凝集 / ATP放出 / 14-3-3ζ / GPIbα / Iso-antibody / Type II-deficiency / Type I-deficiency / Monocytes / Platelet aggregation / GPIV-deficiency / type Iの欠損者 / 骨髄移植 / GPIVのmRNA / イソ抗GPIV抗体 / typeIの欠損者 / 単球 / GPIV欠損 / インヒビタ / 抗体産生細 / 電気的細胞融 / 細胞融合 / イディオタイプ抗体 / インヒビター / 血友病A / ヒト杭体 / MEG-01 / 前骨髄巨核芽球 / 血小板減少性紫斑病 / 自己免疫疾患 / パートナー細胞 / IgG / 融合 / ハイブリドーマ / IIIa複合体 / GPIIb / インフルエンザ抗体 / PDZドメイン / Rho / GTPase / イソフォーム / 巨核球 / RNAi / ノックダウン / RhoGAP / GTP-ase / Nadrin / フォンヴィレブラント因子 / 受容体 / 分子異常症 / 膜糖蛋白 / 遺伝子解析 / Bernard-Soulier症候群 / 血小板無力症 / P-selectin / コラゲン受容体 / GPVI … More
Except Principal Investigator
血小板無力症 / IIIa / mooclonal antibody / fibrinogen / ADP aggregation / thrombin aggregation / Platelet membrane recoptors / Immunocytochemistry / Platelet membrane glycoproteins / 受容体刺激 / トロンビン凝集 / モノクロナール抗体 / フィブリノゲン / ADP凝集 / リストセチン凝集 / 血小板受容体 / 免疫電顕 / 血小板膜糖蛋白 / Drosophila / cell polarity / cytoskeleton / phosphatidylethanolamine / P-type ATPase / flip-flop / phospholipid / biomembrane / アクチン / 上皮細胞 / 細胞極性 / 脂質二重層 / 酵母 / 細胞サイズ / フリップ-フロップ / 膜質二重層 / ショウジョウバエ / 形態形成 / 細胞骨格 / ホスファチジルエタノールアミン / P型ATPase / フリップ・フロップ / リン脂質 / 生体膜 / Plasma Fibrinogen / Intra-Platelet Fibrinogen / Platelet Aggregation / Thrombasthenia / Integrin alpha_<IIb> beta_3 / Platelet GPIIb / 血小板凝集能欠損 / cDNA異常 / PCR法 / Fibrinogen結合部位 / IIIa複合体 / インテグリンα_<IIb> β_3 / 血漿フィブリノゲン / 血小板フィブリノゲン / 血小板凝集 / インテグリンα_<IIb>β_3 / GPIIb Less
  • Research Projects

    (10 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (18 People)
  •  血友病A患者からモノクローナルインヒビターと抗イディオタイプ抗体の作製と抗原解析Principal Investigator

    • Principal Investigator
      山本 正雅
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Ohu University
  •  新しい融合パートナーSPYMEGを用いるヒト抗血小板抗体産生ハイブドーマの作製Principal Investigator

    • Principal Investigator
      山本 正雅
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Ohu University
  •  培養巨核球からの血小板産生に及ぼすNadrinノックダウンの影響Principal Investigator

    • Principal Investigator
      山本 正雅
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Molecular mechanisms of functional differentiation and morphogenesis of cell membranes based on the positional information of membrane phospholipids

    • Principal Investigator
      UMEDA Masato
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University
  •  Study on Outsode-in Signal Transduction via Platelet Membrane Glycoprotein lbPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Naomasa
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      THE TOKYO METROPOLITAN INSTITUT OF MEDICAL SCIENCE
  •  血小板膜糖蛋白GPIb/IX/V複合体の分子異常症の遺伝子解析Principal Investigator

    • Principal Investigator
      山本 正雅
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  血小板コラゲン受容体GPIVとGPVIの単クローン抗体の作成と受容機序の解明Principal Investigator

    • Principal Investigator
      山本 正雅
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Study on mechanism for anti-GPIV antibody production in GPIV-deficient individuals using analysis of cDNA of GPIVPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Naomasa
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science, Department of Cardiovascular Research
  •  Functional Domains on Human Platelet Glycoprotein IIb/IIIa.

    • Principal Investigator
      TANOUE Kenjiro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science.
  •  Electron microscopic analyses on platelet membrane glycoproteins using monoclonal antibodies

    • Principal Investigator
      YAMAZAKI Hiroh
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science

All 2010 2009 2007 2006 2005

All Journal Article Patent

  • [Journal Article] Broad neutralizing human monoclonal antibodies against influenza virus from vaccinated healthy donors2009

    • Author(s)
      Ritsuko Kubota-Koketsu, Hiroyuki Mizuta, Masatoshi Oshita, Shoji Ideno, Mikihiro Yunoki, Motoki Kuhara, Naomasa Yamamoto, Yoshinobu Okuno, Kazuyoshi Ikuta
    • Journal Title

      Biochemical and Biophysical Research Communications 387

      Pages: 180-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659242
  • [Journal Article] The activation of exocytic sites by the formation of phosphatidylinositol-4,5-bisphosphate microdomains at syntaxin clusters.2005

    • Author(s)
      Aoyagi, K., Sugaya, T., Umeda, M., Yamamoto, S., Terakawa, S., Takahashi, M.
    • Journal Title

      J. Biol. Chem. 280

      Pages: 2089-2104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15207015
  • [Patent] 血液酸化抑制器具2010

    • Inventor(s)
      熊野活行、山本正雅、米原典史、小池雄一
    • Industrial Property Rights Holder
      日本システム企画株式会社
    • Industrial Property Number
      2010-134233
    • Filing Date
      2010-06-11
    • Data Source
      KAKENHI-PROJECT-21659242
  • [Patent] 融合パートナー細胞2007

    • Inventor(s)
      山本 正雅, 兼田 瑞穂
    • Industrial Property Rights Holder
      株式会社医学生物学研究所, 山本 正雅
    • Filing Date
      2007-04-13
    • Data Source
      KAKENHI-PROJECT-17659297
  • [Patent] 融合パートナー細胞2006

    • Inventor(s)
      山本 正雅, 兼田 瑞穂
    • Industrial Property Rights Holder
      株式会社医学生物学研究所, 山本 正雅
    • Filing Date
      2006-04-26
    • Data Source
      KAKENHI-PROJECT-17659297
  • 1.  TANOUE Kenjiro (30014137)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  AKAMATU Noriko (30124431)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  SAKURABA Hitoshi (60114493)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  UMEDA Masato (10185069)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  KANEDA Mizuho (50113494)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  新井 盛夫 (00212605)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OHNO Shigeo (10142027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KATAGIRI Yasuhiro (60194768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MATSUNO Kazuhiko (70102332)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KASE Ryoichi (20150203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TAKEUCHI Ken-ichi (70270684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KATO Utako (90362392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  INADOME Hironori (30378872)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAMAZAKI Hiroh (50013826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  鈴木 英紀 (30158977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  前田 美穂 (90173715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  嶋 緑倫 (30162663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  志村 紀子 (60287480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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