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TAKAHASHI Koki  高橋 孝喜

ORCIDConnect your ORCID iD *help
Researcher Number 50171484
External Links
Affiliation (based on the past Project Information) *help 2008: 東京大学, 医学部・附属病院, 教授
2006 – 2007: 東京大学, 医学部附属病院, 教授
1998 – 1999: 沖中記念成人病研究所, 研究員
1995: 冲中記念成人病研究所, 主任研究員
1993 – 1995: 沖中記念成人病研究所, 主任研究員 … More
1992: 東京大学, 医学部(病), 講師
1991: 東京大学, 医学部(病), 助手
1990: 東京大学, 医学部・輸血部, 助手
1989: 東京大学, 医学部, 助手
1988 – 1989: 東京大学, 医学部(病), 助手 Less
Review Section/Research Field
Principal Investigator
General surgery
Except Principal Investigator
Laboratory medicine / 医学一般 / Digestive surgery / Applied pharmacology / Hematology
Keywords
Principal Investigator
主要組織適合抗原 / 東アジア / 民族移動 / HLA / ブリアート族 / 自己フィブリン糊 / 自己血輸血 / 止血効果 / 血管手術 / 植皮術 / 組織修復 / 組識修復 … More
Except Principal Investigator
… More HLA / 大腸癌 / 血小板型 / 血小板抗体 / 血小板輸血 / 血小板輸血不応答 / Platelet Allo-antibody / Platelet Transfusion / 自己輸血法 / 術前貯血法 / スイッチバック式採血、戻し輸血法 / 採血後貧血 / ヒトエリスロポエチン / 投与量、投与回数依存性 / 術前自己血貯血法 / 他家血輸血の完全回避 / 赤血球産生能 / 採血後貧血からの回復 / 東アジア / 日本人 / 中国人 / 韓国人 / 家系調査 / 地域差 / 腫瘍血管 / 血管内皮細胞 / スルフォラファン / ゾレドロン酸 / 選択性セロトニン受容体阻害薬 / 血管内皮前駆細胞 / 集学的治療 / 個別化治療 / ワクチン / Surforaphane / HUVEC / 樹状細胞 / 内皮細胞 / hRFI / 抗癌剤感受性 / アポトーシス / p53 / 血管新生阻害 / HSE / プラウノトール / 血管新生 / 胃癌 / 複合的抗癌治療 / 複合的抗癌薬 / 新生児血小板減少性紫斑病 / 血小板型(HPA) / 新生児血小板減少症柴斑病 / Platelet Allo-antigen / Neonatal Alliommune Thrombocytopenia / 新生児血小板減少紫斑病 / 血小板(HPA) / 新生児血小板減少症紫斑病 / Pletelet Allo-antigen / Neonatal Alloimmune Thrombocytopenia / HLA適合血小板輸血 / 骨髄移植 / ドナー・プール / 非血縁ドナー・プール / ハプロタイプ / 適正規模 / ドナ-・プ-ル / 非血縁ドナ-・プ-ル / HLAハプロタイプ / HLA適合提供者 / HLA matched platelet transfusion / Bone marrow transplantation / Donor pool / Unrelated donor pool / Haplotypes / Appropriate size Less
  • Research Projects

    (9 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (20 People)
  •  植物由来イソプレノイドの抗腫瘍効果および抗血管新生作用についての検討

    • Principal Investigator
      津野 寛和
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      The University of Tokyo
  •  Treatment strategy for colorectal cancer targeted to the tumor vessel

    • Principal Investigator
      NAGAWA Hirokazu
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      The University of Tokyo
  •  Screening of anti-platelet antibodies and prospective study of neonatal alloimmune thrombocytopenia

    • Principal Investigator
      SHIBATA Yoichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      The University of Tokyo
  •  Clinical Significance of Platelet Allo-antibodies.

    • Principal Investigator
      SHIBATA Yoichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      University of Tokyo
  •  主要組織適合抗原システムからみた東アジアにおける民族移動Principal Investigator

    • Principal Investigator
      高橋 孝喜
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  自己フィブリン糊製剤の外科手術への応用使用Principal Investigator

    • Principal Investigator
      桑田 昇治, 高橋 孝喜
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  主要組織適合抗原システムからみた東アジアにおける民族移動

    • Principal Investigator
      TOKUNAGA Katsushi
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒトエリスロポエチンを利用した術前自己血貯血法の確立

    • Principal Investigator
      黒川 高秀
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      医学一般
    • Research Institution
      The University of Tokyo
  •  DETERMINATION OF FREQUENCIES OF HLA HAPLOTYPES IN TOHOKU AREA BASED ON FAMILY STUDY AND EVALUTION OF AN APPROPRIATE SIZE OF UNRELATED DONOR POOL FOR HLA-MATCHED PLATELET TRANSFUSION AND BONE MARROW TRANSPLANTATION

    • Principal Investigator
      JUJI Takeo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo

All 2009 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Sulforaphane stimulates activation of proapoptotic protein bax leading to apoptosis of endothelial progenitor cells2009

    • Author(s)
      Nishikawa T. Tsuno NH. Tsuchiya T. Yoneyama S. Yamada J. Shuno Y. Okaji Y. Tanaka J. Kitayama J. Takahashi K. Nagawa H.
    • Journal Title

      Annals of Surgical Oncology 16(2)

      Pages: 534-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Journal Article] Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation2009

    • Author(s)
      Yamada J. Tsuno NH. Kitayama J. Tsuchiya T. Yoneyama S. Asakage M. Okaji Y. Shuno Y. Nishikawa T. Tanaka J. Takahashi K. Nagawa H.
    • Journal Title

      Journal of Surgical Research 151(1)

      Pages: 115-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Journal Article] Pilot study of anti-angiogenic vaccine using fixed whole endothelium in patients with progressive malignancy after failure of conventional therapy2008

    • Author(s)
      Okaji Y, Tsuno NH, Tanaka M, Yoneyama S, Matsuhashi M, Kitayama J.. Saito S, Nagura Y, Tsuchiya T, Yamada J, Tanaka J, Yoshikawa N, Nishikawa T, Shuno Y, Todo T, Saito N, Takahashi K, Nagawa H.
    • Journal Title

      Eur J Cancer 44(3)

      Pages: 383-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Journal Article] A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model2007

    • Author(s)
      Yoneyama S. Okaji Y. Tsuno NH. Kawai K. Yamashita H. Tsuchiya T. Yamada J. Sunami E. Osada T. Kitayama J. Takahashi K. Nagawa H.
    • Journal Title

      Eur J Surg Oncol 33(10)

      Pages: 1191-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Journal Article] Early-outgrowth of endothelial progenitor cells can function as antigen-presenting cells2006

    • Author(s)
      Asakage M. Tsuno NH. Kitayama J. Kawai K. Okaji Y. Yazawa K. Kaisaki S. Osada T. Watanabe T. Takahashi K. Nagawa H.
    • Journal Title

      Cancer Immunology, Immunotherapy 55(6)

      Pages: 708-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Journal Article] Sulforaphane induces inhibition of human umbilical vein endothelial cells proliferation by apoptosis2006

    • Author(s)
      Asakage M. Tsuno NH. Kitayama J. Tsuchiya T. Yoneyama S. Yamada J. Okaji Y. Kaisaki S. Osada T. Takahashi K. Nagawa H.
    • Journal Title

      Angiogenesis 9(2)

      Pages: 83-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Journal Article] Anti-angiogenic properties of plaunotol.2005

    • Author(s)
      Kawai K, Tsuno NH, Kitayama J, Takahashi K, Nagawa H, et al.
    • Journal Title

      Anticancer Drugs. 2005 Apr;16(4) : 401-7. 16(4)

      Pages: 401-407

    • Data Source
      KAKENHI-PROJECT-18659156
  • [Journal Article] 先端のバイオ研究を知る2005

    • Author(s)
      大梶祐頼, 津野寛和, 高橋孝喜, 名川弘一
    • Journal Title

      テクノ・トレンド新たな癌治療法の開発 腫瘍血管内皮細胞・腫瘍内マクロファージの選択的分離について バイオテクノロジージャーナル 5(4)

      Pages: 457-459

    • Data Source
      KAKENHI-PROJECT-17209045
  • [Presentation] 選択的5-HT4受容体アゴニストによる抗血管新生作用2008

    • Author(s)
      西川武司, 津野寛和, 須並英二, 北山丈二, 高橋孝喜, 名川弘一
    • Organizer
      第67回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Presentation] 腫瘍血管の形成スルフォラファンは前アポトーシスタンパク質Baxを活性化し内皮前駆細胞のアポトーシスを誘導する2007

    • Author(s)
      西川武司, 津野寛和, 高橋孝喜, 北山丈二, 名川弘一
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Presentation] 癌に対する血管新生標的治療の現状と将来内皮細胞ワクチンは腫瘍血管内皮細胞に対する免疫応答を誘導する2006

    • Author(s)
      津野寛和, 大梶祐頼, 朝蔭正宏, 田中実, 米山さとみ, 土屋剛史, 山田純, 北山丈二, 藤堂具紀, 渡辺聡明, 名川弘一, 高橋孝喜
    • Organizer
      第107回日本外科学会
    • Place of Presentation
      東京
    • Year and Date
      2006-03-31
    • Data Source
      KAKENHI-PROJECT-17209045
  • [Presentation] スルフォラファンのアポトーシスによる内皮細胞増殖抑制2006

    • Author(s)
      朝蔭正宏, 津野寛和, 北山丈二, 川合一茂, 谷澤健太郎, 大梶祐頼, 土屋剛史, 米山さとみ, 山田純, 高橋孝喜, 名川弘一
    • Organizer
      第64回日本癌学会総会
    • Year and Date
      2006-09-29
    • Data Source
      KAKENHI-PROJECT-17209045
  • 1.  TSUNO Hirokazu (50282637)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 12 results
  • 2.  KUWATA Shoji (00241993)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  JUJI Takeo (20009997)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  TOKUNAGA Katsushi (40163977)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  SHIBATA Yoichi (30010474)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  KITAYAMA Joji (20251308)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 7.  NAGAWA Hirokazu (80228064)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 8.  TAKEI Yoshiki (10372369)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  脇本 信博 (90191733)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SUNAMI Eiji (70345205)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  MAEJIMA Masamoto (10251307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MIYAZAKI Hiroshi (00134007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  黒川 高秀 (90010298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  幕内 晴朗 (10111543)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  小塚 裕 (10126055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  釣田 義一郎 (80345206)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  渡邉 聡明 (80210920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  上條 亜紀 (30361489)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  AKAZA Tatsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  渡辺 聡明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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