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NISHIGORI Chikako  錦織 千佳子

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Researcher Number 50198454
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2016 – 2018: 神戸大学, 医学研究科, 教授
2015: 神戸大学, 医学(系)研究科(研究院), 教授
2012: 神戸大学, 医学(系)研究科(研究院), 教授
2008 – 2011: Kobe University, 大学院・医学研究科, 教授
2007 – 2008: Kobe University, 医学研究科, 教授 … More
2007: 神戸大学, 医学系研究科, 教授
2005: 神戸大学, 大学院医学系研究科, 教授
2003 – 2004: Kobe University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2003: 神戸大学, 医学系研究科, 教授
2002: 京都大学, 医学研究科, 助教授
1999 – 2001: 京都大学, 医学研究科, 講師
1995 – 1998: Kyoto Univ., Asssistant Prof., 医学研究科, 助手
1992 – 1994: 京都大学, 医学部, 助手
1990 – 1991: 京都大学, 保健診療所, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology / Biological Sciences
Except Principal Investigator
Dermatology / Otorhinolaryngology / Medical sociology / Human genetics / Pathological medical chemistry / Dermatology
Keywords
Principal Investigator
紫外線 / ピリミジンダイマー / 色素性乾皮症 / 遺伝子治療 / IL-10 / (6-4)光産物 / XPAマウス / HVJ-リポゾーム / T4エンドヌクレアーゼ / 免疫抑制 … More / gene therapy / Xeroderma Pigmentosum / PCR-RFLP / 皮膚癌 / 皮膚がん / 酸化ストレス / 遺伝子多型 / UVB / 遅延型過敏反応 / リポゾーム / 無毛マウス / 皮膚腫瘍 / 点突然変異 / ras遺伝子 / 太陽光 / 表皮角化細胞 / 活性酸素 / 小胞体ストレス / ロドデノール / グルタチオン / 色素細胞 / アポトーシス / N-アセチルシステイン / 白斑 / ERストレス / 美白剤 / メラノサイト / ultraviolet light / skin tumor / nucleotide excision repair / HVJ-liposomes / xeroderma pigmentosum / 遺伝子導入 / サンバーン細胞 / HVJリポゾーム / ヌクレオチド除去修復 / Pyrimidine dimers / UDS (unscheduled DNA Synthesis) / XPA mice / pCAGGS / pCHA / XPAモデルマウス / マウス / 不定期DNA合成 / Founder Effect / Gene Diagnosis / Mutation / RFLP / XPAL遺伝子 / 突然変異 / 創始者効果 / 遺伝子診断 / 8ヒドロキシグアニン / 光発がん / 長波長紫外線 / 8-ヒドロキシグアニン / メラノーマ / グルタチオンS-トランスフェラーゼ / 免疫機構 / GST / 悪性黒色腫 / IL-4 / プロスタグランディンE_2 / ノックアウトマウス / EP_4 / 接触過敏反応 / プロスタグランディン / UDS(不定期DNA合成能) / 不定期DNA合成期(UDS) / 色素性乾皮症A群 / ポリミジンダイマー / TNF-α / サイトカイン / IL‐10 / ピリミジンタイマー / p53遺伝子 / ピリミジン / 太陽光紫外線 / Cu(II) / 過酸化水素 / 3-ヒドロキシアントラニル酸 / ニッケル化合物 / 複合汚染 / ヒト遺伝子損傷 / 重金属化合物 / 環境変異原 … More
Except Principal Investigator
色素性乾皮症 / 紫外線 / DNA修復 / 皮膚がん / 突然変異 / DNA repair / ultraviolet light / skin cancer / xeroderma pigmentosum / がん抑制遺伝子 / がん遺伝子 / XPAモデルマウス / 感音難聴 / Announcement / Counseling / Education / Walfare / Medicine / Database / Internet / Dowm Syndrome / 告知 / カウンセリング / 療育 / 福祉 / 医療 / データベース / インターネット / ダウン症 / Wound healing / Contact Dermatitis / Ultraviolet / Knockout mice / Prostanoid Receptor / Prostanoids / 創傷治療 / 創傷治癒 / 接触皮膚炎 / ノックアウトマウス / プロスタノイド受容体 / プロスタノイド / mutation / inherited disease / 遺伝病 / Tunisia / Korea / China / sun exposure / 色素性乾皮性 / チュニジア / 韓国 / 中国 / メラノーマ / CpGisland / 次世代シークエンサー / ビスルファイトシークエンシング / CpGアレー / CpGアイランド / タイリングアレー / DNAメチル化阻害剤 / メチル化 / メチル化阻害剤 / ゲノムワイド / MDS / メチローム解析 / AML / CpG island / 5Azacytidine / DNAメチル化 / 骨髄異形成症候群 / 5アザシチジン / 白血病 / メチローム / 5AZ治療 / 骨髄異形性症候群 / シグナル伝達 / 代謝型グルタミン酸受容体 / 悪性黒色腫 / cDNA / 融合蛋白 / フィプロネクチン / エピトープ / 自己抗体 / 7型コラーゲン / 後天性表皮水疱症 / 活性酸素 / P53遺伝子 / ras遺伝子 / 修復 / 遺伝要因 Less
  • Research Projects

    (28 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (33 People)
  •  Role of oxidative stress in the cytotoxicity caused by skin whitening agentsPrincipal Investigator

    • Principal Investigator
      Nishigori Chikako
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  Clarification of pathological condition and therapeutic development of Xeroderma pigmentosum with model mice experiments

    • Principal Investigator
      KOJIMA Yasutaka
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kobe University
  •  Epigenome analysis of cancer

    • Principal Investigator
      NISHIKAWA Shinichi
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Relevance of near UV to the development of skin cancerPrincipal Investigator

    • Principal Investigator
      NISHIGORI Chikako
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  The role of mGluR1 expression in melanoma progression

    • Principal Investigator
      FUNASAKA Yoko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  日本人皮膚がん発症における宿主側素因の検討Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  日本人悪性黒色腫患者における発症素因の検討Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Longterm gene therapy of xeroderma pigmentosum group A mice using HVJ-liposomes.Principal Investigator

    • Principal Investigator
      NISHIGORI Chikako
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
      Kyoto University
  •  紫外線による免疫抑制作用におけるプロスタグランディンE_2の関与Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Kyoto University
  •  リポゾームを用いた色素性乾皮症A群遺伝子治療の試みPrincipal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  GENE THERAPY TRIAL FOR XERODERMA PIGMENTOSUM GROUP using xeroderma pigmentosum model mice USING LIPOSMESE.Principal Investigator

    • Principal Investigator
      NISHIGORI Chikako
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kyoto University
  •  色素性乾皮症A群マウスへのHVJリポゾームを用いた遺伝子治療Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  太陽光紫外線によるDNA傷害の免疫系に及ぼす影響Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  色素性乾皮症A群マウスを用いたリポゾーム遺伝子治療の試みPrincipal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  ダウン症に関する医療社会的情報データベースの構築

    • Principal Investigator
      TATSUMI Junko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical sociology
    • Research Institution
      KYOTO UNIVERSITY
  •  太陽光による細胞傷害の免疫系に及ぼす影響Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  色素性乾皮症における免疫の異常Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Kyoto University
  •  Physiological and pathological analyses of prostagland in receptor knockout mouse skin

    • Principal Investigator
      IKAI Kouichi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      KYOTO UNIVERSITY
  •  後天性表皮水疱症抗原のエピトープの検索

    • Principal Investigator
      TANAKA Toshihiro
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kyoto University
  •  Types, sites and frequency of XP-gene mutations in xeroderma pigmentosum patients.

    • Principal Investigator
      TATSUMI Junko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      KYOTO UNIVERSITY
  •  多段階発がんを促進する遺伝要因の作用機構

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  太陽光紫外線による突然変異の生成Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Molecular Biological Diagnosis of Xeroderma Pigmentosum group A and Clinical CharacteristicsPrincipal Investigator

    • Principal Investigator
      MATSUYOSHI Norihisa, 錦織 千佳子
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      KYOTO UNIVERSITY
  •  環境変異原と重金属化合物との相互作用によるヒト遺伝子損傷と複合汚染における意義Principal Investigator

    • Principal Investigator
      川西 正祐, 錦織 千佳子
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  多段階発がん過程を促進する遺伝的要因の作用機構

    • Principal Investigator
      TAKEBE Hiraku
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  太陽光紫外線による遺伝子の変化Principal Investigator

    • Principal Investigator
      錦織 千佳子
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  多段階発がん過程を促進する遺伝的要因の作用機構

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Gene distribution of xeroderma pigmentosum in East Asia and North Africa

    • Principal Investigator
      TAKEBE Hiraku
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyoto University

All 2018 2016 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] 最新美容皮膚科診療ナビゲーション2018

    • Author(s)
      錦織千佳子
    • Total Pages
      184
    • Publisher
      学研メディカル秀潤社
    • ISBN
      9784780909524
    • Data Source
      KAKENHI-PROJECT-16K10156
  • [Book] 皮膚科サブスペシャリティーシリーズ1冊でわかる光皮膚科 皮膚科医に必須のphotodermatology2008

    • Author(s)
      錦織 千佳子
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Book] 図説分子病態学4版2008

    • Author(s)
      錦織千佳子
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Book] 皮膚科サブスペシャリティーシリーズ1冊でわかる光皮膚科-皮膚科医に必須のphotodermatology-2008

    • Author(s)
      錦織千佳子
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Book] Environmental Dermatology:環境・職業からみた皮膚疾患2007

    • Author(s)
      錦織千佳子
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Book] 皮膚科診療プラクティス20 Environmental Dermatology環境・職業からみた皮膚疾患2007

    • Author(s)
      錦織千佳子
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Book] 光科学研究の最前線2005

    • Author(s)
      錦織千佳子
    • Total Pages
      476
    • Publisher
      強光子場科学研究懇談会
    • Data Source
      KAKENHI-PROJECT-17015029
  • [Book] 別冊医学のあゆみ レドックス医学-ストレス防御の医学2005

    • Author(s)
      錦織千佳子
    • Total Pages
      230
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-17015029
  • [Book] カラーアトラス皮膚診断の技法 皮膚をみると全身が見える(岩月啓氏, 宮地良樹 編)2004

    • Author(s)
      錦織 千佳子
    • Total Pages
      357
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-16024211
  • [Journal Article] 4-(4-Hydroxyphenyl)-2-butanol (rhododendrol)-induced melanocyte cytotoxicity is enhanced by UVB exposure through generation of oxidative stress2018

    • Author(s)
      Goto Noriko、Tsujimoto Mariko、Nagai Hiroshi、Masaki Taro、Ito Shosuke、Wakamatsu Kazumasa、Nishigori Chikako
    • Journal Title

      Experimental Dermatology

      Volume: Epub Issue: 7 Pages: 754-762

    • DOI

      10.1111/exd.13555

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10156
  • [Journal Article] Four types of possible founder mutations are responsible for 87% of Japanese patients with Xeroderma pigmentosum variant type2008

    • Author(s)
      Masaki T, Ono R, Tanioka M, Funasaka Y, Nagano T, Moriwaki S, Nishigori C
    • Journal Title

      J Dermatol Sci 52

      Pages: 144-148

    • NAID

      10024457638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma.2008

    • Author(s)
      Ohtani Y, Harada T, Funasaka Y(these 3 authors contributed equally), Nakao K, Takahara C, Abdel-Daim M, Sakai N, Saito N, Nishigori C, Aiba A
    • Journal Title

      Oncogene 27

      Pages: 7162-7170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591306
  • [Journal Article] Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma2008

    • Author(s)
      Ohtani Y, Harada T, Funasaka Y, Nakao K, Takahara C, Abdel-Daim M, Sakai N, Saito N, Nishigori C, Aiba A
    • Journal Title

      Oncogene 27

      Pages: 7162-7170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] In vitro expansion of immature melanoblasts and their ability to repopulate melanocyte stem cells in the hair follicle2008

    • Author(s)
      Yonetani S, Osawa M, Moriyama M, Maku S, Nishigori C, Nishikawa S
    • Journal Title

      J Invest Dermatol 128

      Pages: 408-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] Involvement of interleukin-10 promoter polymorphism in non-melanoma skin cancers-A case study in non-carcinoma skin cancer patients2008

    • Author(s)
      Nagano T, Kunisada M, Yu X, Masaki T, Nishigori C
    • Journal Title

      Photochem Photobiol 84

      Pages: 63-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] Antiproliferative activity of IL-27 on melanoma2008

    • Author(s)
      Yoshimoto T, Morishima N, Mizuguchi I, Shimizu M, Nagai H, Oniki S, Oka M, Nishigori C, Mizuguchi J
    • Journal Title

      J Immunol 180

      Pages: 6527-6535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] エビデンスに基づいたUVB療法-安全性と有効性のバランス-2008

    • Author(s)
      錦織千佳子
    • Journal Title

      日本皮膚科学会誌(増) 118

      Pages: 2768-2872

    • NAID

      10025378815

    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] 「皮膚科セミナリウム」高発癌性皮膚疾患 : 遺伝と皮膚癌色素性乾皮症2007

    • Author(s)
      錦織千佳子
    • Journal Title

      日本皮膚科学会誌 117

      Pages: 15-22

    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] 紫外線発癌2007

    • Author(s)
      錦織千佳子
    • Journal Title

      日本皮膚科学会誌 117(増)

      Pages: 2201-2203

    • NAID

      10020565897

    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] Narrow-band UVB induced more carcinogenic skin tumors than broadband UVB through the formation of cyclobutane pyrimidine dimmer2007

    • Author(s)
      Kunisada M, Kumimoto H, Ishizaki K, Sakumi K, Nakabeppu Y, Nishigori C
    • Journal Title

      J Invest Dermatol 127

      Pages: 2865-2871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type2007

    • Author(s)
      Tanioka M, Masaki T, Ono R, Nagano T, Otoshi-Honda E, Matsumura Y, Takigawa M, Inui T, Miyachi Y, Moriwaki S, Nishigori C
    • Journal Title

      J Invest Dermatol 127

      Pages: 1745-1751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Journal Article] Cellular aspects of photocarcinogenesis.2006

    • Author(s)
      Chikako Nishigori
    • Journal Title

      Photochem Photobiol Sci 5・2

      Pages: 208-214

    • Data Source
      KAKENHI-PROJECT-17015029
  • [Journal Article] Impaired removal of 8-hydroxydeoxyguanosine induced by UVB radiation in naevoid basal cell carcinoma syndrome cells.2005

    • Author(s)
      Chikako Nishigori
    • Journal Title

      Br J Dermatol 153・Suppl2

      Pages: 52-56

    • Data Source
      KAKENHI-PROJECT-17015029
  • [Journal Article] Role of reactive oxygen species in skin carcinogenesis.2004

    • Author(s)
      Nishigori C
    • Journal Title

      Redox Signal 6・3

      Pages: 561-570

    • Data Source
      KAKENHI-PROJECT-16024211
  • [Journal Article] Fibroblasts from patients with nevoid basal cell carcinoma syndrome are slightly impaired in removal of UVB induced 8-hydrroxydeoxyguanosine

    • Author(s)
      Nishigori C
    • Journal Title

      Br J Dermatol (未定)(in press)

    • Data Source
      KAKENHI-PROJECT-16024211
  • [Presentation] N-acetylcysteine (NAC)は紫外線によるロドデノールの色素細胞障害性増強効果を軽減する2016

    • Author(s)
      後藤典子, 辻本昌理子, 永井宏, 正木太朗, 伊藤祥輔, 若松一雅, 錦織千佳子
    • Organizer
      第27回日本色素細胞学会年次学術大会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜県岐阜市)
    • Year and Date
      2016-11-12
    • Data Source
      KAKENHI-PROJECT-16K10156
  • [Presentation] Crucial role of phospholipase Cε in ultraviolet B irradiation-induced skin inflammation and skin tumor development2008

    • Author(s)
      Oka M, Kamo T, Edamatsu H, Kunisada M, Kataoka T, Nishigori C
    • Organizer
      34th Meeting of the American Society for Photobiology
    • Place of Presentation
      Burlingame, CA, USA
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Presentation] Relevance to the UV wavelength in carcinogenesis2007

    • Author(s)
      Nishigori C
    • Organizer
      21th World Congress of Dermatology
    • Place of Presentation
      Buenos Aires, Argentina
    • Data Source
      KAKENHI-PROJECT-19390296
  • [Presentation] Relevance to the UV wavelength in carcinogenesis.2007

    • Author(s)
      Nishigori C
    • Organizer
      21th World Congress of Dermatology
    • Place of Presentation
      Buenos Aires, Argentina
    • Data Source
      KAKENHI-PROJECT-19390296
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