SAKUMI Kunihiko 作見邦彦

Researcher Number	50211933
Other IDs
Affiliation (based on the past Project Information) *help	2023: 九州大学, 生体防御医学研究所, 准教授 2007 – 2021: Kyushu University, 生体防御医学研究所, 准教授 2016: 九州大学, 生体防御研究所, 准教授 2006: 九州大学, 生体防御医学研究所, 助教授 2003 – 2004: 九州大学, 生体防御医学研究所, 助教授 … More 1995 – 2001: Kyushu University, Medical Inst.Bioregulation, 生体防御医学研究所, 助手 1994: 生体防御医学研究所, 助手 1990 – 1991: Kyushu University, Medical Institute of Bioregulation Research Associate, 生体防御医学研究所, 助手 1990: 九州大学生体防御医学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Laboratory animal science / Health science and related fields / Tumor biology / Experimental pathology / Living organism molecular science Except Principal Investigator Molecular biology / Risk sciences of radiation/Chemicals / Basic Section 44010:Cell biology-related / Neurochemistry/Neuropharmacology / Risk sciences of radiation and chemicals / 遺伝 / Biological Sciences
Keywords	Principal Investigator 突然変異 / 遺伝子欠損マウス / 8-オキソグアニン / OGG1遺伝子 / 肺腫瘍 / ヌクレオチドプール / ATP / ヌクレオチド / イノシン / ITPase … More / MTH1遺伝子 / メチルトランスフェラーゼ / MGMT遺伝子 / 抗癌剤 / O^6-メチルグアニン / 酸化ストレス / MUTYH / OGG1 / MTH1 / エクソーム解析 / ミューテーターマウス / がんと遺伝 / 生殖細胞突然変異 / 8-oxoguanine / mutation / 発がん / 化学修飾 / 副作用 / ダカルバジン / MGMT / DNA修復 / ゲノム障害 / 凍結保存 / 生殖細胞 / ８-オキソグアニン / 体外受精 / 遺伝 / 遺伝性腫瘍 / lung / spontaneous tumorigenesis / OGG1 gene / MTH1 gene / 肺 / 自然発癌 / mth1 gene / lung tumor / ogg1 gene / gene-disrupted mouse / methyltransferase / chemotherapeutic agent / dacarbazine / OィイD16ィエD1-methylguanine / knockout mouse / O^6メチルグアニン / MNU / O^<96>-メチルグアニン / ノックアウトマウス / アルキル化剤 / 癌 … More Except Principal Investigator DNA修復 / 突然変異 / 活性酸素 / 発がん / アルキル化剤 / DNA repair / DNA損傷 / 自然突然変異 / 8-オキソグアニン / 遺伝子ターゲティング / 遺伝子欠損マウス / alkylating agent / spontaneous mutation / ミューテーター / 環境ストレス / 次世代影響 / gene cloning / 神経細胞死 / 活性酵素 / 2-OH-dATP / 8-oxoguanine / Reactive oxygen / 酸化DNA損傷 / gene targeting / mutation / 遺伝子 / oxidation / carcinogenesis / 遺伝子クローニング / メチルトランスフェラーゼ / 酸化 / Mutation / メチルトランスフェラ-ゼ / 転写調節 / DNA修復酵素 / 脱アミノ化ヌクレオチド / 酸化ヌクレオチド / 病態モデル / 化学物質 / アルツハイマー病 / ヌクレオチドプール / 神経変性 / 細胞死 / 放射線 / 継世代影響 / ゲノム維持機構 / 生殖細胞ゲノム / 遺伝情報維持 / 生殖細胞ゲノム変異 / 配偶子ゲノム / 卵子 / ゲノム維持 / 精子DNA損傷 / 卵子DNA修復 / ８－オキソグアニン / ミクログリア / ８-オキソグアニン / アミロイドーシス / 神経新生 / 加齢 / ミクログリオーシス / 神経炎症応答 / 生物影響 / 生殖細胞 / ゲノム変異 / ミスマッチ修復 / 生殖細胞変異 / methyltransferase / induced mutation / DNA polymerase / replication fidelity / DNAポリメラーゼ / 発がんの抑制 / 遺伝子のクローニング / 遺伝情報 / アルキル科剤 / DNA複製 / 誘導突然変異 / 遺伝子クロ-ニング / DNAポリメラ-ゼ / 複製精度 / amyotrophic lateral sclerosis / Parkinson's disease / neurodegeneration / mitochondria / 2-hydroxyadenine / Reactive Oxigen Species / 肺腫瘍 / 基質認識 / 筋萎縮性側索硬化症 / パーキンソン病 / ミトコンドリア / 2-ハイドロキシアデニン / mouse / E.coli / oxidized RNA / cancer / active oxygen / 細胞株 / マウス / 大腸菌 / 酸化RNA / Tumor suppressor gene / 8-oxo-guanine / Carcinogenesis / Oxidative stress / アポトーシス / β-オキソグアニン / 2ーOH-dATP / DNA修飾 / 8ーオキソグアニン / 癌抑制遺伝子 / 酸化ストレス / MTH1 gene / replication error / DNA replication / DNA precursor / mutation rate / 塩基置換 / 変異タンパク / 酸化塩基 / 遺伝子障害 / DNA合成前駆体 / 胃がん / 自然発がん / 自然突然変異率 / O^6-methylguanine / repair methyltransferase / gene-defective mouse / monoclonal antibody / modified base / O^6-メチルグアニン / 修復メチルトランスフェラーゼ / モノクローナル抗体 / 修復塩基 / DNA damage / guanine / cloning / gene / mutator / グアニン / クローニング / cell death / gene-targeting / oxygen radical / 染色体変異 / 突然変異制御 / ヌクレオチド / DNA合成 / ヌクレオチド代謝 / 酸化型グアニン / 8-oxodGTPase / ノックアウトマウス / 遺伝子破壊マウス / Adaptive Response / Alkylating Agent / Ada Regulon / Gene Expression / Transcriptional Control / DNA Damage / DNA Repair Enzyme / DNA修復酸素 / 抗がん剤 / 突然変異の誘起 / 適応応答 / adaレギュロン / 遺伝子発現 / 環境スレス / 細胞増殖阻害 / 酸化的損傷 / バイスタンダー効果 / RNA / DNA / 選択的化学療法 / 遺伝子発現制御 / Mer^ー形質 / ヒト腫瘍細胞 / メチル転移酵素 Less

Understanding molecular mechanism behind the oocyte's DNA repair ability of sperm genome damage
- Principal Investigator
  
  Ohno Mizuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kyushu University
An attempt to quantify and evaluate the effect of in vitro fertilization on the genomic information of offspringPrincipal Investigator
- Principal Investigator
  
  SAKUMI KUNIHIKO
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  Kyushu University
Investigation of brain damage caused by reactive oxygen species and its defense mechanisms
- Principal Investigator
  
  Yusaku Nakabeppu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyushu University
Clarification of the mechanism of germline mutation occurrence that causes familial tumorPrincipal Investigator
- Principal Investigator
  
  SAKUMI KUNIHIKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
Analysis of de novo germline mutations by using environmental genome stress-sensitive mice
- Principal Investigator
  
  Ohno Mizuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyushu University
Molecular pathology and regulatory mechanisms involved in the breakdown of nucleotide pool homeostasis under environmental stress
- Principal Investigator
  
  NAKABEPPU YUSAKU
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyushu University
環境ストレスによるヌクレオチドプールの恒常性破綻の分子病態と制御機構の解明
- Principal Investigator
  
  中別府雄作
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyushu University
プリンヌクレオチドの酸化と脱アミノ化に起因する突然変異と発がんPrincipal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
「ITPaseによるATPプールの品質維持機構」に普遍性はあるかPrincipal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyushu University
プリンヌクレオチドの脱アミノ化に起因する突然変異と発がんPrincipal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Molecular mechanism of development and repression of lung tumor in OGG1 knockout mousePrincipal Investigator
- Principal Investigator
  
  SAKUMI Kunihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
DNA修復酵素遺伝子欠損マウスを用いた発癌抑制機構の解析Principal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
発癌抑制に果たすDNA修復酵素の役割Principal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Biological phenomena caused by 8-oxoguanine in DNAPrincipal Investigator
- Principal Investigator
  
  SAKUMI Kunihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  KYUSHU UNIVERSITY
発癌抑制に果たすDNA修復酵素の役割Principal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Regulatory mechanisms for mutagenesis and carcinogenesis
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Study of Defense Mechanisms against Cellular Damage Caused by Free Radicals
- Principal Investigator
  
  NAKABEPPU Yusaku
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYUSHU UNIVERSITY
DNA修復メチルトランスフェラーゼによるアルキル化発癌の抑制Principal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
ゲノムDNA上のO^6-メチルグアニンに起因する生命現象Principal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Oxygen-induced DNA damage and its repair mechamism
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  KYUSHU UNIVERSITY
Susceptibility to chemotherapeutic alkylating agents depends on the MGMT genotypePrincipal Investigator
- Principal Investigator
  
  SAKUMI Kuihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  KYUSHU UNIVERSITY
DNA修復メチルトランスフェラーゼによるアルキル化発癌の抑制Principal Investigator
- Principal Investigator
  
  作見邦彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Repair of alkylation DNA damage
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Mechanism for control of mutagenesis in mammals
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  遺伝
- Research Institution
  Fukuoka Dental College
Active Oxygen-induced DNA Damage and its Repair Mechanisms
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYUSHU UNIVERSITY
Mechanisms os spontaneous mutation and its control
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Fukuoka Dental College
  Kyushu University
O^6ーアルキルグアニンーアルキル転移酵素の制がんと発がんにおける役割
- Principal Investigator
  
  池永満生
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Molecular mechanisms of the adaptive response to alkylating agents
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYUSHU UNIVERSITY
Maintenance of Genetic Information and Mutagenesis Mechanisms
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1986 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyushu University

[Book] Ganglion Cells: Morphology, Functional Development and Role in Disease2014
- Author(s)
  Sango, K., Niimi, N., Tsukamoto, M., Utsunomiya, K., Sakumi, K., Nakabeppu, Y., Kadoya, T., and Horie, H.
- Total Pages
  139
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-22221004
[Book] Ganglion Cells: Morphology, Functional Development and Role in Disease2014
- Author(s)
  Sango K, Niimi N, Tsukamoto M, Utsunomiya K, Sakumi K, Nakabeppu Y, Kadoya T, Horie H
- Total Pages
  158
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] Mth1 deficiency provides longer survival upon intraperitoneal crocidolite injection in female mice2020
- Author(s)
  Funahashi Satomi、Okazaki Yasumasa、Akatsuka Shinya、Takahashi Takashi、Sakumi Kunihiko、Nakabeppu Yusaku、Toyokuni Shinya
- Journal Title
  
  Free Radical Research
  
  Volume: N/A Issue: 2-3 Pages: 1-231
- DOI
  10.1080/10715762.2020.1743285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05462, KAKENHI-PROJECT-17H01391, KAKENHI-PROJECT-17H04064, KAKENHI-PROJECT-20K07588, KAKENHI-PROJECT-16H02468, KAKENHI-PUBLICLY-20H05502
[Journal Article] Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance in Ogg1-/- mice2020
- Author(s)
  Kvandova, M., Filippou, K., Steven, S., Oelze, M., Kalinovic, S., Stamm, P., Frenis, K., Vujacic-Mirski, K., Sakumi, K., Nakabeppu, Y., Bagheri Hosseinabadi, M., Dovinova, I., Epe, B., Munzel, T., Kroller-Schon, S. and Daiber, A.
- Journal Title
  
  Free Radical Research
  
  Volume: in press Issue: 4 Pages: 280-292
- DOI
  10.1080/10715762.2020.1754410
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01391
[Journal Article] Germline mutation: <i>de novo</i> mutation in reproductive lineage cells2019
- Author(s)
  Sakumi Kunihiko
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 94 Issue: 1 Pages: 3-12
- DOI
  10.1266/ggs.18-00055
- NAID
  130007625027
- ISSN
  1341-7568, 1880-5779
- Year and Date
  2019-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19913
[Journal Article] 8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes2019
- Author(s)
  Haruyama, N., Sakumi, K., Katogi, A., Tsuchimoto, D., De Luca, G., Bignami, M., and Nakabeppu, Y.
- Journal Title
  
  Progress in Neurobiology
  
  Volume: 180 Pages: 101613-101613
- DOI
  10.1016/j.pneurobio.2019.04.002
- NAID
  120006839234
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01391
[Journal Article] Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation2017
- Author(s)
  Castillo Erika、Leon Julio、Mazzei Guianfranco、Abolhassani Nona、Haruyama Naoki、Saito Takashi、Saido Takaomi、Hokama Masaaki、Iwaki Toru、Ohara Tomoyuki、Ninomiya Toshiharu、Kiyohara Yutaka、Sakumi Kunihiko、LaFerla Frank M.、Nakabeppu Yusaku
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17762-17762
- DOI
  10.1038/s41598-017-17999-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290017, KAKENHI-PROJECT-17H01391
[Journal Article] Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model.2017
- Author(s)
  Li GH, Akatsuka S, Chew SH, Jiang L, Nishiyama T, Sakamoto A, Takahashi T, Futakuchi M, Suzuki H, Sakumi K, Nakabeppu Y, Toyokuni S.
- Journal Title
  
  Pathol Int.
  
  Volume: 67 Issue: 11 Pages: 564-574
- DOI
  10.1111/pin.12598
- NAID
  120006382249
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19913, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-17H01391, KAKENHI-PROJECT-15H04298, KAKENHI-PROJECT-17H04064, KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-16H02468
[Journal Article] 生殖細胞突然変異2017
- Author(s)
  作見邦彦
- Journal Title
  
  地域ケアリング
  
  Volume: 19 Pages: 89-95
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04298
[Journal Article] 生殖細胞突然変異2017
- Author(s)
  作見邦彦
- Journal Title
  
  BIO Clinica
  
  Volume: 32 Pages: 90-96
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04298
[Journal Article] Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis.2017
- Author(s)
  Takemori C, Kunisada M, Yogianti F, Oka S, Sakumi K, Ono R, Nakabeppu Y, Nishigori C.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 85 Issue: 2 Pages: 140-143
- DOI
  10.1016/j.jdermsci.2016.10.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10126, KAKENHI-PROJECT-17K19913, KAKENHI-PROJECT-15H04298
[Journal Article] Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells.2016
- Author(s)
  Y. Yoneshima, N. Abolhassani, T. Iyama, K. Sakumi, N. Shiomi, M. Mori, T. Shiomi, T. Noda, D. Tsuchimoto, and Y. Nakabeppu
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 32849-32849
- DOI
  10.1038/srep32849
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04298
[Journal Article] Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration.2016
- Author(s)
  K. Sango, S. Takaku, N. Niimi, T. Kadoya, H. Yako, M. Tsukamoto, K. Sakumi, Y. Nakabeppu, and H. Horie
- Journal Title
  
  AIMS Molecular Science
  
  Volume: 3 Issue: 3 Pages: 325-337
- DOI
  10.3934/molsci.2016.3.325
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298, KAKENHI-PROJECT-16K07048
[Journal Article] Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.2016
- Author(s)
  S. Oka, J. Leon, K. Sakumi, T. Ide, D. Kang, F.M. LaFerla, and Y. Nakabeppu
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 37889-37889
- DOI
  10.1038/srep37889
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298, KAKENHI-PROJECT-15K15085
[Journal Article] 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions2016
- Author(s)
  Julio, Leon, Sakumi Kunihiko, Castillo Erika, Sheng Zijing, Oka Sugako, Nakabeppu Yusaku.
- Journal Title
  
  Scientific Reports
  
  Volume: 25 Issue: 1 Pages: 22086-22086
- DOI
  10.1038/srep22086
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460490, KAKENHI-PROJECT-15K15085, KAKENHI-PROJECT-15H04298, KAKENHI-PROJECT-25461281
[Journal Article] Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine2016
- Author(s)
  Evans, M. D., Misty, V., Singh, R., Gackowski, D., Rozalski, R., Siomek, A., Phillips, D. H., Zuo, J., Mullenders, L., Pines, A., Nakabeppu, Y., Sakumi, K., Sekiguchi, M., Tsuzuki, T., Bignami, M., Farmer, P. B., Oliski, R., Cooke, M. S.
- Journal Title
  
  Free Radic. Biol. Med.
  
  Volume: 99 Pages: 385-391
- DOI
  10.1016/j.freeradbiomed.2016.08.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25241012, KAKENHI-PROJECT-15H04298, KAKENHI-PROJECT-16H05109, KAKENHI-PROJECT-26340040, KAKENHI-PROJECT-16K12605
[Journal Article] PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E-deficient mice.2016
- Author(s)
  K. Torisu, X. Zhang, M. Nonaka, T. Kaji, D. Tsuchimoto, K. Kajitani, K. Sakumi, T. Torisu, K. Chida, K. Sueishi, M. Kubo, J. Hata, T. Kitazono, Y. Kiyohara, and Y. Nakabeppu
- Journal Title
  
  Genes Cells
  
  Volume: 21 Issue: 10 Pages: 1030-1048
- DOI
  10.1111/gtc.12402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04298
[Journal Article] Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia.2014
- Author(s)
  Nomaru, H., Sakumi, K., Katogi, A., Ohnishi, Y.N., Kajitani, K., Tsuchimoto, D., Nestler, E.J., and Nakabeppu, Y.
- Journal Title
  
  Glia
  
  Volume: N/A Issue: 8 Pages: 1284-1298
- DOI
  10.1002/glia.22680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-24591735, KAKENHI-PROJECT-25870494
[Journal Article] 8-oxoguanine causes spontaneous de novo germline mutations in mice.2014
- Author(s)
  Ohno, M., Sakumi, K., Fukumura, R., Furuichi, M., Iwasaki, Y., Hokama, M., Ikemura, T., Tsuzuki, T., and Nakabeppu, Y.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 4689-4689
- DOI
  10.1038/srep04689
- NAID
  120005703609
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PLANNED-24108009, KAKENHI-PROJECT-25241012, KAKENHI-PROJECT-25241016
[Journal Article] MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death2014
- Author(s)
  Oka S, Leon J, Tsuchimoto D, Sakumi K, Nakabeppu Y
- Journal Title
  
  Oncogenesis
  
  Volume: 3 Issue: 10 Pages: 1-10
- DOI
  10.1038/oncsis.2014.35
- NAID
  120005703608
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-25461281
[Journal Article] Inhibitory effects of dietary Spirulina platensis on UVB induced skin inflammatory responses and carcinogenesis.2014
- Author(s)
  Yogianti, F., Kunisada, M., Nakano, E., Ono, R., Sakumi, K., Oka, S., Nakabeppu, Y., and Nishigori, C.
- Journal Title
  
  J Invest Dermatol
  
  Volume: N/A Issue: 10 Pages: 2610-2619
- DOI
  10.1038/jid.2014.188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-25461281, KAKENHI-PROJECT-25461668
[Journal Article] Galectin-1 deficiency improves axonal swelling of motor neurons in SOD1 transgenic mice.2014
- Author(s)
  Kobayakawa, Y., Sakumi, K., Kajitani, K., Kadoya, T., Horie, H., Kira, J.I., and Nakabeppu, Y.
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: N/A Issue: 2 Pages: 227-244
- DOI
  10.1111/nan.12123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PUBLICLY-25110724, KAKENHI-PROJECT-25293204, KAKENHI-PROJECT-25870494
[Journal Article] GDNF promotes neurite outgrowth and upregulates galectin-1 through the RET/PI3K signaling in cultured adult rat dorsal root ganglion neurons.2013
- Author(s)
  Takaku S, Yanagisawa H, Watabe K, Horie H, Kadoya T, Sakumi K, Nakabeppu Y, Poirier F, Sango K.
- Journal Title
  
  Neurochem Int
  
  Volume: 62 Issue: 3 Pages: 330-339
- DOI
  10.1016/j.neuint.2013.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-22500324, KAKENHI-PROJECT-24500428, KAKENHI-PROJECT-25430056
[Journal Article] fosB-Null Mice Display Impaired Adult Hlppocampal Neurogenesis and Spontaneous Epilepsy2013
- Author(s)
  Yutsudo, N, et. al.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 38 Issue: 5 Pages: 895-906
- DOI
  10.1038/npp.2012.260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00463, KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-23500498, KAKENHI-PROJECT-23657116, KAKENHI-PROJECT-24591299, KAKENHI-PROJECT-24591735
[Journal Article] Skin tumours induced by narrowband UVB have higher frequency of p53 mutations than tumours induced by broadband UVB independent of Ogg1 genotype.2012
- Author(s)
  Yogianti F, Kunisada M, Ono R, Sakumi K, Nakabeppu Y, Nishigori C.
- Journal Title
  
  Mutagenesis
  
  Volume: 26 Issue: 6 Pages: 637-643
- DOI
  10.1093/mutage/ges029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.2012
- Author(s)
  Sheng, Z., et. al.
- Journal Title
  
  The Journal of clinical investigation
  
  Volume: 122 Issue: 12 Pages: 4344-4361
- DOI
  10.1172/jci65053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00463, KAKENHI-PROJECT-22221004
[Journal Article] 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction.2012
- Author(s)
  Sampath H, Vartanian V, Rollins MR, Sakumi K, Nakabeppu Y, Lloyd RS.
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 12 Pages: e51697-e51697
- DOI
  10.1371/journal.pone.0051697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] Cancer-Related PRUNE2 Protein Is Associated with Nucleotides and Is Highly Expressed in Mature Nerve Tissues.2011
- Author(s)
  Iwama, E., D.Tsuchimoto, T.Iyama, K.Sakumi, A.Nakagawara, K.Takayama, Y.Nakanishi, Y.Nakabeppu.
- Journal Title
  
  J Mol Neurosci.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis2011
- Author(s)
  Oka S, Nakabeppu Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 4 Pages: 677-682
- DOI
  10.1111/j.1349-7006.2011.01869.x
- NAID
  10029291748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-22501014
[Journal Article] ニトロソ化ストレスによるイノシン三リン酸の生成と細胞応答2011
- Author(s)
  作見邦彦, 土本大介, 中別府雄作
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 175-180
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] FosB Is Essential for the Enhancement of Stress Tolerance and Antagonizes Locomotor Sensitization by ΔFosB2011
- Author(s)
  Ohnishi YN, et.al.
- Journal Title
  
  Biological Psychiatry
  
  Volume: 70-5 Issue: 5 Pages: 487-495
- DOI
  10.1016/j.biopsych.2011.04.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00463, KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-23657116
[Journal Article] Oxidative stress-induced tumorigenesis in the small intestines of DNA repair-deficient mice2011
- Author(s)
  Tsuzuki T, Piao JS, Isoda T, Sakumi K, Nakabeppu Y, Nakatsu Y
- Journal Title
  
  Health Phys
  
  Volume: 100 Pages: 293-294
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] Increased expression of versican in the inflammatory response to UVB-and reactive oxygen species-induced skin tumorigenesis2011
- Author(s)
  Kunisada M, Yogianti F, Sakumi K, Ono R, Nakabeppu Y, Nishigori C
- Journal Title
  
  Am J Pathol
  
  Volume: 176 Issue: 6 Pages: 3056-3065
- DOI
  10.1016/j.ajpath.2011.08.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] A comprehensive screening system for damaged nucleotide-binding proteins.2010
- Author(s)
  Tsuchimoto, D., T.Iyama, M.Nonaka, N.Abolhassani, E.Ohta, K.Sakumi, Y.Nakabeppu.
- Journal Title
  
  Mutat Res
  
  Volume: 703 Pages: 37-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.2010
- Author(s)
  Abolhassani, N., T.Iyama, D.Tsuchimoto, K.Sakumi, M.Ohno, M.Behmanesh, Y.Nakabeppu.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38 Pages: 2891-2903
- NAID
  120005227421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.2010
- Author(s)
  Abolhassani N, Iyama T, Tsuchimoto D, Sakumi K, Ohno M, Behmanesh M, Nakabeppu Y.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 38 Pages: 2891-2903
- NAID
  120005227421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241013
[Journal Article] ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.2010
- Author(s)
  Sakumi, K., N.Abolhassani, M.Behmanesh, T.Iyama, D.Tsuchimoto, Y.Nakabeppu.
- Journal Title
  
  Mutat Res
  
  Volume: 703 Pages: 43-50
- NAID
  120005227205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] NUDT16 and ITPA play a dual protective role in maintaining chromoso me stability and cell growth by eliminating dIDP/IDP and dIDP/IDP from nucleotide pools in mammals.2010
- Author(s)
  Abolhassani N, Iyama T, Tsuchi moto D, Sakumi K, Ohno M, B ehmanesh M, Nakabeppu Y
- Journal Title
  
  Nucleic Acids Res. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012038
[Journal Article] Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.2010
- Author(s)
  Nakabeppu, Y., S.Oka, Z.Sheng, D.Tsuchimoto, K.Sakumi.
- Journal Title
  
  Mutat Res
  
  Volume: 703 Pages: 51-58
- NAID
  120005227112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004
[Journal Article] ITPase-deficient mice show growth retardation and die before weaning.2009
- Author(s)
  Behmanesh M, Sakumi K, Abolh assani N, 他
- Journal Title
  
  Cell Death Differ. Vol.16
  
  Pages: 1315-1322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012038
[Journal Article] hydrogen in Driking Water Reduces Dopaminergic neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease.2009
- Author(s)
  Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, Yamaguchi H, Sakumi K, 他
- Journal Title
  
  PLoS ONE vol.4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012038
[Journal Article] Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A.2007
- Author(s)
  Miyata K, Yasukawa T, Fukuda M, Takeuchi T, Yamazaki K, Sakumi K 他
- Journal Title
  
  Cell Death Differ. 14(4)
  
  Pages: 716-726
- NAID
  120001871682
- Data Source
  KAKENHI-PROJECT-18012035
[Journal Article] Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.2006
- Author(s)
  Nakabeppu Y, Sakumi K, Sakamoto K, Tsuchimoto D, Tsuzuki T, Nakatsu Y
- Journal Title
  
  Biol. Chem. 387(4)
  
  Pages: 373-379
- Data Source
  KAKENHI-PROJECT-18012035
[Journal Article] MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine2006
- Author(s)
  Yamaguchi H, Kajitani K, Dan Y, Furuichi M, Ohno M, Sakumi K, Kang D, Nakabeppu Y
- Journal Title
  
  Cell Death Differ. 13(4)
  
  Pages: 551-563
- Data Source
  KAKENHI-PROJECT-18012035
[Journal Article] A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome.2006
- Author(s)
  Ohno M, Miura T, Furuichi M, Tominaga Y, Tsuchimoto D, Sakumi K, Nakabeppu Y
- Journal Title
  
  Genome Res. 16(5)
  
  Pages: 567-575
- Data Source
  KAKENHI-PROJECT-18012035
[Journal Article] The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice.2006
- Author(s)
  Arima T, Yamasaki K, John RM, Kato K, Sakumi K, Nakabeppu Y, Wake N, Kono T
- Journal Title
  
  Genomics. 88(5)
  
  Pages: 650-658
- Data Source
  KAKENHI-PROJECT-18012035
[Journal Article] A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA.2005
- Author(s)
  Ushijima Y, Tominaga Y, Miura T, Tsuchimoto D, Sakumi K, Nakabeppu Y.
- Journal Title
  
  Nucleic Acids Research 33(2)
  
  Pages: 672-682
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA.2005
- Author(s)
  Ushijima Y, Tominaga Y, Miura T, Tsuchimoto D, Sakumi K, Nakabeppu Y
- Journal Title
  
  Nucleic Acids Res. 33(2)
  
  Pages: 672-682
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA2005
- Author(s)
  Ushijima Y, Tominaga Y, Miura T, Tsuchimoto D, Sakumi K, Nakabeppu Y.
- Journal Title
  
  Nucleic Acids Res. 33(2)
  
  Pages: 672-682
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice2004
- Author(s)
  Ide Y, Tsuchimoto D, Tominaga Y, Nakashima M, Watanabe T, Sakumi K, Ohno M, Nakabeppu Y.
- Journal Title
  
  Blood 104(13)
  
  Pages: 4097-4103
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts.2004
- Author(s)
  Ichinoe A, Behmanesh M, Tominaga Y, Ushijima Y, Hirano S, Sakai Y, Tsuchimoto D, Sakumi K, Wake N, Nakabeppu Y
- Journal Title
  
  Nucleic Acids Res. 32(2)
  
  Pages: 477-487
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice.2004
- Author(s)
  Ide Y, Tsuchimoto D, Tominaga Y, Nakashima M. Watanabe T, Sakumi K, Ohno M, Nakabeppu Y.
- Journal Title
  
  Blood 104(13)
  
  Pages: 4097-4103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death2004
- Author(s)
  Nakabeppu Y, Tsuchimoto D, Furuichi M, Sakumi K.
- Journal Title
  
  Free Radic Res. 38(5)
  
  Pages: 423-429
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain2004
- Author(s)
  Tominaga Y, Ushijima Y, Tsuchimoto D, Mishima M, Shirakawa M, Hirano, Sakumi K, Nakabeppu Y.
- Journal Title
  
  Nucleic Acids Res. 32(10)
  
  Pages: 3198-3211
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Galectin-1beta, a natural monomeric form of galectin-1 lacking its six aminoterminal residues promotes axonal regeneration but not cell death2004
- Author(s)
  Miura T, Takahashi M, Horie H, Kurushima H, Tsuchimoto D, Sakumi K, Nakabeppu Y.
- Journal Title
  
  Cell Death Differ. 11(10)
  
  Pages: 1076-1083
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain.2004
- Author(s)
  Tominaga Y, Ushijima Y, Tsuchimoto D, Mishima M, Shirakawa M, Hirano S, Sakumi K, Nakabeppu Y.
- Journal Title
  
  Nucleic Acids Research 32(10)
  
  Pages: 3198-3211
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Galectin-1beta, a natural monomeric form of galectin-1 lacking its six ainino-terminal residues promotes axonal regeneration but not cell death.2004
- Author(s)
  Miura T, Takahashi M, Horie H, Kurushima H, Tsuchimoto D, Sakumi K, Nakabeppu Y
- Journal Title
  
  Cell Death Differ. 11(10)
  
  Pages: 1076-1083
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species : from mitochondria to nuclei.2004
- Author(s)
  Nakabeppu Y, Tsuchimoto D, Ichinoe A, Ohno M, Ide Y, Hirano S, Yoshimura D, Tominaga Y, Fnruichi M, Sakumi K.
- Journal Title
  
  Ann N Y Acad Sci. 1011
  
  Pages: 101-111
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice.2004
- Author(s)
  Ide Y, Tsuchimoto D, Tominaga Y, Nakashima M, Watanabe T, Sakumi K, Ohno M, Nakabeppu Y
- Journal Title
  
  Blood 104(13)
  
  Pages: 4097-4103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death.2004
- Author(s)
  Nakabeppu Y, Tsuchimoto D, Furuichi M, Sakumi K.
- Journal Title
  
  Free Radical Research 38(5)
  
  Pages: 423-429
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species : from mitochondria to nuclei2004
- Author(s)
  Nakabeppu Y, Tsuchimoto D, Ichinoe A, Ohno M, Ide Y, Hirano S, Yoshimura D, Tominaga Y, Furuichi M, Sakumi K.
- Journal Title
  
  Ann N Y Acad Sci. 1011
  
  Pages: 101-111
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species : from mitochondria to nuclei.2004
- Author(s)
  Nakabeppu Y, Tsuchimoto D, Ichinoe A, Ohno M, Ide Y, Hirano S, Yoshimura D, Tominaga Y, Furuichi M, Sakumi K
- Journal Title
  
  Ann N Y Acad Sci. 1011
  
  Pages: 101-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain.2004
- Author(s)
  Tominaga Y, Ushijima Y, Tsuchimoto D, Mishima M, Shirakawa M, Hirano S, Sakumi K, Nakabeppu Y
- Journal Title
  
  Nucleic Acids Res. 32(10)
  
  Pages: 3198-3211
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Galectin-1beta, a natural monomeric form of galectin-1 lacking its six amino-terminal residues promotes axonal regeneration but not cell death.2004
- Author(s)
  Miura T, Takahashi M, Horie H, Kurushima H, Tsuchimoto D, Sakumi K, Nakabeppu Y.
- Journal Title
  
  Cell Death and Differentiation 11(10)
  
  Pages: 1076-1083
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death.2004
- Author(s)
  Nakabeppu Y, Tsuchimoto D, Furuichi M, Sakumi K
- Journal Title
  
  Free Radic Res. 38(5)
  
  Pages: 423-429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption.2003
- Author(s)
  Sakumi K, Tominaga Y, Furuichi M, Xu P, Tsuzuki T, Sekiguchi M, Nakabeppu Y.
- Journal Title
  
  Cancer Res. 63(5)
  
  Pages: 902-905
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] 酸化ストレスとがん2003
- Author(s)
  作見邦彦, 中別府雄作
- Journal Title
  
  BIO Clinica 18
  
  Pages: 1265-1270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress.2003
- Author(s)
  Yoshimura D, Sakumi K, Ohno M, Sakai Y, Furuichi M, Iwai S, Nakabeppu Y
- Journal Title
  
  J Biol Chem. 278(39)
  
  Pages: 37965-37973
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Ogg1 knockout-associated lung turnorigenesis and its suppression by Mth1 gene disruption.2003
- Author(s)
  Sakumi K, Tominaga Y, Furuichi M, Xu P, Tsuzuki T, Sekiguchi M, Nakabeppu Y.
- Journal Title
  
  Cancer Research 63
  
  Pages: 902-905
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Ogg1 knockout mouse.2003
- Author(s)
  Sakumi K, Nakabeppu Y.
- Journal Title
  
  Bunshi Kokyukibyo 7(6)
  
  Pages: 565-570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Oxdative stress and cancer.2003
- Author(s)
  Sakumi K, Nakabeppu Y.
- Journal Title
  
  BIO Clinica 18(14)
  
  Pages: 1265-1270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Ogg1ノックアウトマウス2003
- Author(s)
  作見邦彦, 中別府雄作
- Journal Title
  
  分子呼吸器病 7
  
  Pages: 565-570
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] An oxidized purine nucleoside triphosphatase, MTH1 suppresses cell death caused by oxidative stress.2003
- Author(s)
  Yoshimura D, Sakumi K, Ohno M, Sakai Y, Furuichi M, Iwai S, Nakabeppu Y.
- Journal Title
  
  Journal of Biological Chemistry 278
  
  Pages: 37965-37973
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Journal Article] Mutator phenotype of MUTYH-null mouse embryonic stem cells.2003
- Author(s)
  Hirano S, Tominaga Y, Ichinoe A, Ushijima Y, Tsuchimoto D, Honda-Ohnishi Y, Ohtsubo T, Sakumi K, Nakabeppu Y
- Journal Title
  
  J Biol Chem. 278(40)
  
  Pages: 38121-38124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590347
[Presentation] マウスにおける神経幹細胞特異的ITPA欠損は神経細胞の脱分極を引き起こし，てんかん性発作と早期死亡の原因となる2019
- Author(s)
  土本大介，古賀祐一郎，林良憲，アボルハッサニノナ，米嶋康臣，作見邦彦，中西博，豊國伸哉，中別府雄作
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] 加齢雌マウス脳に蓄積する8-オキソグアニンは海馬歯状回と大カレハ島の神経新生を障害し性的二形性をきたす2019
- Author(s)
  春山直樹，作見邦彦，加藤木敦央，土本大介，中別府雄作
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] 8-Oxoguanine accumulation in aged female brain impairs neurogenesis in dentate gyrus and major island of Calleja, and thus causing sexually dimorphic phenotypes2019
- Author(s)
  Yusaku Nakabeppu, Naoki Haruyama, Kunihiko Sakumi, Atsuhisa Katogi, Daisuke Tsuchimoto, Gabriele De Luca, Margherita Bignami
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] Defense mechanisms against the dysfunction resulting from damage to the genome by reactive oxygen species during aging2019
- Author(s)
  Naoki Haruyama, Nona Abolhassani, Guianfranco Mazzei, Julio Leon, Zijing Sheng, Sugako Oka, Mizuki Ohno, Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  The 2019 International Association of Gerontology and Geriatrics (IAGG) Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] Accumulation of 8-oxoguanine in nuclear genome of neural progenitors in aged mouse brain causes atrophy of major island of Calleja resulting in locomotor hyperactivity2018
- Author(s)
  Naoki Haruyama, Kunihiko Sakumi, Atsuhisa Katogi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  The 41st Annual Meeting of The Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] 生殖細胞ゲノム変異の発生原因と遺伝情報維持を担う分子機構2018
- Author(s)
  大野みずき、鷹野典子、作見邦彦
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] The impact of DNA repair status on germline mutation rate and spectra in mice2018
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Teruhisa Tsuzuki
- Organizer
  SMBE2018 (Society for Molecular Biology and Evolution)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] Accumulation of 8-oxoguanine in nuclear genome of neural progenitors in aged mouse brain causes atrophy of major island of Calleja resulting in locomotor hyperactivity.2018
- Author(s)
  Naoki Haruyama, Kunihiko Sakumi, Atsuhisa Katogi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  The 41st Annual Meeting of The Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] Oxidative DNA damage and Repair in Cancer and Aging2018
- Author(s)
  Yusaku Nakabeppu, Nona Abolhassani, Eiko Ohta, Zijing Sheng, Mizuki Ohno, Daisuke Tsuchimoto, Kunihiko Sakumi
- Organizer
  The 14th Japan - Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] Oxidative DNA damage and Repair in Cancer and Aging.2018
- Author(s)
  Yusaku Nakabeppu, Nona Abolhassani, Eiko Ohta, Zijing Sheng, Mizuki Ohno, Daisuke Tsuchimoto, Kunihiko Sakumi
- Organizer
  The 14th Japan - Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] Impaired hippocampal neurogenesis in APP mouse model of Alzheimer disease2017
- Author(s)
  Guianfranco Mazzei, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  Third International meeting in Bioscience (Young Peruvian Scientist Network)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] 側坐核・カレハ島の新生GABAニューロンへの8-オキソグアニンの蓄積は加齢マウスの多動の原因となる2017
- Author(s)
  春山直樹, 作見邦彦, 加藤木　敦央, 土本大介, 中別府　雄作
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] 遺伝性大腸がんモデルマウスにおける酸化ストレス誘発発がんと体細胞突然変異の解析2017
- Author(s)
  大野みずき, 鷹野典子, 佐々木史子, 作見邦彦, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] 遺伝性大腸がんモデルマウスにおける酸化ストレス誘発発がんと体細胞突然変異の解析2017
- Author(s)
  大野みずき, 鷹野典子, 佐々木史子, 作見邦彦, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Somatic mutation analysis of oxodative stress-induced colon cancer model2017
- Author(s)
  大野みずき, 鷹野典子, 高野京子, 作見邦彦, 中別府雄作, 中津可道, 續輝久
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] イノシン三リン酸分解酵素ITPA欠損症のモデルマウス作製と解析2017
- Author(s)
  土本大介, 古賀祐一郎, 米嶋康臣, 浅田真司, 作見邦彦, 中別府雄作
- Organizer
  平成28年度「先端モデル動物支援プラットフォーム成果発表会」
- Place of Presentation
  大津
- Year and Date
  2017-02-06
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Ferric nitrilotriacetate induced renal tumorigenesis in MUTYH-deficient mice2017
- Author(s)
  赤塚慎也, 李光華, 作見邦彦, 中別府　雄作, 二口充, 鈴木拓, 豊國伸哉
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 遺伝性疾患自然発症モデル動物としてのmutator mouse2017
- Author(s)
  作見邦彦, 大野みずき, 中別府雄作
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] 遺伝性疾患自然発症モデル動物としてのmutator mouse2017
- Author(s)
  作見邦彦, 大野みずき, 中別府雄作
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Somatic mutation analysis of oxodative stress-induced colon cancer model2017
- Author(s)
  大野みずき, 鷹野典子, 高野京子, 作見邦彦, 中別府雄作, 中津可道, 續輝久
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] Nuclear accumulation of 8-oxoguanine in nucleus accumbens neurons contributes to age-related locomotor hyperactivity in Mth1/Ogg1-double knockout mice2017
- Author(s)
  Naoki Haruyama, Atsuhisa Katogi, Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  九州大学教育改革シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] Accumulation of 8-oxoguanine in the nuclei of newly-generated GABAergic neurons in the nucleus accumbens and islands of Calleja contributes to locomotor hyperactivity in aged mice2017
- Author(s)
  Naoki Haruyama, Kunihiko Sakumi, Atsuhisa Katogi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  The 27th Hot Spring Harbor International Symposium
- Data Source
  KAKENHI-PROJECT-17H01391
[Presentation] Regulation of base substitution mutagenesis and chromosome recombination induced by 8-oxoguanine accumulated in the genome2016
- Author(s)
  大野みずき、作見邦彦、中別府雄作
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Impaired hippocampal neurogenesis in App-knock-in model mice of Alzheimer’s disease2016
- Author(s)
  Guianfranco Mazzei, Erika Castillo, Kunihiko Sakumi, Takashi Saito, Takaomi Saido, Yusaku Nakabeppu
- Organizer
  The 39th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] マウス脳におけるFOSBアイソフォームによる遺伝子発現調節機構の解析2016
- Author(s)
  加藤木敦央, 大西克典, 作見邦彦, 中別府雄作
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 8-オキソグアニンに起因する生殖細胞突然変異と家族性腫瘍2016
- Author(s)
  作見邦彦
- Organizer
  平成 27 年度「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  大津
- Year and Date
  2016-02-03
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] イノシン三リン酸分解酵素ITPA欠損の哺乳動物細胞およびマウス中枢神経系への影響の解析2016
- Author(s)
  土本大介, 米嶋康臣, 古賀祐一郎, Nona Abolhassani, 猪山輝昭, 浅田真司, 作見邦彦, 塩見尚子, 森雅彦, 塩見忠博, 野田哲生, 中別府雄作
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Comparative gene expression profiling of triple-transgenic 3xTg-AD and APP-knock-in model mice of Alzheimer’s disease2016
- Author(s)
  Erika Castillo, Julio Leon, Nona Abolhassani, Guianfranco Mazzei, Kunihiko Sakumi, Takashi Saito, Takaomi Saido, Yusaku Nakabeppu
- Organizer
  The 46th Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Cell death induced by MUTYH-initiated base excision repair plays a role in p53-mediated tumor suppression2016
- Author(s)
  岡素雅子、フリオレオン、土本大介、作見邦彦、中別府雄作
- Organizer
  平成 27 年度「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  大津
- Year and Date
  2016-02-03
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] アルツハイマー病進展における核あるいはミトコンドリアDNA中に蓄積した8-oxoguanineの役割2016
- Author(s)
  岡素雅子, 盛子敬, フリオレオン, 土本大介, 作見邦彦, 中別府雄作
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Regulation of base substitution mutagenesis and chromosome recombination induced by 8-oxoguanine accumulated in the genome2016
- Author(s)
  Ohno Mizuki, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  The 39th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Mth1, Ogg1, Mutyh 三重欠損マウス家系を用いた生殖細胞突然変異の解析2015
- Author(s)
  作見邦彦, 大野みずき, 権藤洋一, 續輝久, 中別府雄作
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Influence of oxidative DNA damage on the rate of somatic and germline mutation2015
- Author(s)
  Ohno Mizuki, Takano Noriko, SAKUMI Kunihiko, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs2015
- Author(s)
  Sugako Oka, Ohno Mizuki, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  BIT’ 8th, Annual World Cancer Congress-2015
- Place of Presentation
  Beijing, China
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 生殖細胞自然突然変異の新規発生と変異アリールの伝達2015
- Author(s)
  作見邦彦, 大野みずき, 古市正人, 續輝久, 中別府雄作
- Organizer
  第44回日本環境変異学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 8-oxoguanine causes spontaneous de novo germline mutations in mice2015
- Author(s)
  Kunihiko Sakumi, Mizuki Ohno, Masato Furuichi, Teruhisa Tsuzuki, Yusaku Nakabeppu
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 生殖細胞自然突然変異の新規発生と変異アリールの伝達2015
- Author(s)
  作見邦彦, 大野　みずき, 古市正人, 續輝久, 中別府雄作
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Role of the oxidative DNA damage repair system in somatic and germline mutations in mice2015
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  Zing conference "Genome Integrity"
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-07-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] The role of MUTYH in the oxidative stress-induced mutagenesis and tumorigenesis in the mouse intestine2015
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  The Zing conference on “Genomic Integrity"
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] MUTYHによる塩基除去修復過程に依存して誘導される細胞死はp53の発がん抑制機構の１つとして機能する2015
- Author(s)
  岡素雅子, フリオレオン, 土本大介, 作見邦彦, 中別府雄作
- Organizer
  第44回日本環境変異学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 活性酸素によるDNA損傷が引起こすさまざまな生命現象：突然変異から神経変性まで2015
- Author(s)
  中別府雄作, 岡素雅子, 盛子敬, 大野みずき, 土本大介, 作見邦彦
- Organizer
  第17回日本進化学会年大会
- Place of Presentation
  東京
- Year and Date
  2015-08-20
- Invited
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] Cortical neurons isolated from adult Mth1/Ogg1-double-knockout mouse exhibit impaired neurite regeneration under conditions of oxidative stress2015
- Author(s)
  Julio Jesusu Leon Incio, Kunihiko Sakumi, Sugako Oka, Erika Castillo, Yusaku Nakabeppu
- Organizer
  The 38th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 8-Oxoguanine accumulated in mitochondrial DNA disturbs neuritic regeneration of cultured adult mouse cortical neurons under conditions of oxidative stress2015
- Author(s)
  Julio Leon, Kunihiko Sakumi, Sugako Oka, Erika Castillo, Yusaku Nakabeppu
- Organizer
  45th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] MUTYH-dependent programmed cell death triggered by 8-oxoguanine and its implication in tumor suppression and neurodegeneration2015
- Author(s)
  Yusaku Nakabeppu, Sugako Oka, Zijing Sheng, Kunihiko Sakumi
- Organizer
  15th International Congress of Radition Research: ICRR2015
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04298
[Presentation] 8-Oxoguanine causes spontaneous de novo germline mutations : a study from the mutator mouse line.2014
- Author(s)
  Mizuki Ohno, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Yoshimichi Ikemura, Teruhisa Tsuzuki, Yoichi Gondo, Yusaku Nakabeppu
- Organizer
  SMBE Satellite Meeting/NIG International Symposium: The Causes of Genome Evolution
- Place of Presentation
  三島
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Oxidation of nucleic acids and control mechanisms of genetic diversity in mammals.2014
- Author(s)
  Yusaku Nakabeppu, Mizuki Ohno, Ryutaro Fukumura, Yuki Iwasaki, Yoshimichi Ikemura, Teruhisa Tsuzuki, Yoichi Gondo, Kunihiko Sakumi
- Organizer
  International Symposium on Germline Mutagenesis and Biodiversification
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Dual effects of Galectin-1 in amyotrophic lateral sclerosis2013
- Author(s)
  Yuko Kobayakawa, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  Neuro2013 Joint Conference
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Striatal degeneration initiated by a mitochondrial toxin, 3-nitropropionic acid is dependent on MUTYH-initiated base excision repair of 8-oxoguanine-paired adenine.2013
- Author(s)
  Yusaku Nakabeppu, Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi
- Organizer
  11th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-Oxoguanine in brain causes complex neurodegeneration through DNA repair2013
- Author(s)
  38. Zing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  Gordon research conference on Oxidative Stress & Disease
- Place of Presentation
  Les Diablerets, Switzerland
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] デオキシイノシン三リン酸の蓄積はミスマッチ修復機構に依存した細胞増殖抑制とゲノム不安定性を引き起こす.2013
- Author(s)
  米嶋康臣, 土本大介, 外間政朗, Abolhassani Nona, 猪山輝昭, 作見邦彦, 塩見尚子, 森雅彦, 塩見忠博, 中別府雄作
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Dual effects of Galectin-1 in amyotrophic lateral screlosis.2013
- Author(s)
  Yuko Kobayakawa, Kunihiko Sakumi, yusaku Nakabeppu
- Organizer
  The 43rd annual meeting of the Society for neuroscience
- Place of Presentation
  San Diego. CA, USA.
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer's disease model mice.2013
- Author(s)
  岡素雅子, Julio Leon, 外間政朗, 加藤木敦央, 作見邦彦, 井手友美, Kang Dongchon, 中別府雄作
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Comprehensive analysis of gene expression regulated by Fosb gene in brain-derived cells2013
- Author(s)
  Hiroko Nomaru, Kunihiko Sakumi, Noriko Yutsudo, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  Neuro2013 Joint Conference
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 活性酸素による核酸の酸化と哺乳動物における遺伝子多様性の制御機構2013
- Author(s)
  中別府雄作, 大野みずき, 作見邦彦
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer’s disease model mice.2013
- Author(s)
  Sugako Oka, Julio Leon, Masaaki Hokama, Atsuhisa Katogi, Sakumi Kunihiko, Dongchon Kang, Yusaku Nakabeppu
- Organizer
  International Symposium on Mitochondria 2013
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Control mechanism to maintain the low level of deoxyinosine in DNA.2013
- Author(s)
  Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  Keystone Symposium on Genomic Instability and DNA Repair (X6)
- Place of Presentation
  Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Fosb gene products regulate expression of C5ar1 and C5l2 genes and microglial activation.2013
- Author(s)
  Hiroko Nomaru, Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  The 43rd annual meeting of the Society for neuroscience
- Place of Presentation
  San Diego. CA, USA.
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior2013
- Author(s)
  33. Noriko Yutsudo, Takashi Kamada, Kosuke Kajitani, Hiroko Nomaru, Atsuhisa Katogi, Yoko H. Ohnishi, Yoshinori N. Ohnishi, Kei-ichiro Takase, Kunihiko Sakumi, Hiroshi Shigeto, Yusaku Nakabeppu
- Organizer
  Neuro2013 Joint Conference
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Fosb遺伝子産物は補体C5aレセプターの遺伝子発現を制御することにより，ミクログリアの活性化に寄与している．2013
- Author(s)
  能丸寛子，作見邦彦，加藤木敦央，大西克典，梶谷康介，土本大介，Eric J. Nestler，中別府雄作
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 核酸損傷と生体防御2013
- Author(s)
  中別府雄作, 岡素雅子, 盛子敬, 土本大介, 作見邦彦
- Organizer
  第24回日本生体防御学会学術集会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Cytotoxic effects of X-ray irradiation on proliferating and differentiated human neuroblastoma cell line SH-SY5Y, and their modulation by BDNF and inhibitors for CDK5 and calpains.2013
- Author(s)
  Erika Castillo, Julio Leon, 秋本頼子, 作見邦彦, 岡素雅子, 土本大介, 中別府雄作
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-Oxoguanine in brain causes complex neurodegeneration through DNA repair.2013
- Author(s)
  Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi & Yusaku Nakabeppu
- Organizer
  Gordon Research Conference on Oxidative Stress & Disease
- Place of Presentation
  Les Diablerets, Switzerland
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Cross-talk between insulin and other growth factors signaling regulate their neuroprotective functions.2013
- Author(s)
  Julio Leon, Masaaki Hokama, Sugako Oka, Kunihiko Sakumi, Daisuke Tsuchimoto, Erika Castillo, Yusaku Nakabeppu
- Organizer
  11th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析 (II)2013
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩崎裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析2013
- Author(s)
  大野みずき, 作見邦彦, 福村龍太郎, 権藤洋一, 岩崎裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 変異SOD1トランスジェニックマウスを用いた，筋萎縮性側索硬化症におけるガレクチン1の病態への関与の検討.2012
- Author(s)
  小早川優子，作見邦彦，中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Synergistic interaction between insulin and other growth factors modulates their neuroprotective functions.2012
- Author(s)
  Julio Leon, Masaaki Hokama, Sugako Oka, Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-Oxoguanine causes complex neurodegeneration in a MUTYH-dependent manner, which can be efficiently suppressed by MTH1 and/or OGG1.2012
- Author(s)
  Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi and Yusaku Nakabeppu
- Organizer
  The 8th 3R Symposium (International Symposium on DNA Replication, Recombination and Repair)
- Place of Presentation
  Yumebutai, Awaji, Hyogo
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] fosB遺伝子産物によるアナフィラトキシンC5a走化性受容体遺伝子C5arとGpr77の発現制御機構の解析.2012
- Author(s)
  能丸寛子，作見邦彦，土本大介，中別府雄作
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-オキソグアニンの修復機構をノックアウトするマウスは，生殖細胞ゲノム中の突然変異頻度の上昇と遺伝性の変異形質を呈する.2012
- Author(s)
  大野みずき，作見邦彦，福村龍太郎，権藤洋一，續輝久，中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Influence of 8-Oxoguanine on Mitotic and Meiotic Chromosome.2012
- Author(s)
  Mizuki Ohno, Kunihiko Sakumi, Teruhisa Tsuzuki, Yusaku Nakabeppu
- Organizer
  The 10th International Symposium on Chromosomal Aberrations
- Place of Presentation
  Amalfi, Italy
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化ストレスは MUTYH による塩基除去修復経路を介してcalpain/PARP 依存性の神経変性を引き起こす.2012
- Author(s)
  盛子敬，岡素雅子，土本大介，作見邦彦，中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化損傷塩基の修復機構をノックアウトするマウス家系の解析.2012
- Author(s)
  大野みずき，作見邦彦，福村龍太郎，権藤洋一，田口健一，續輝久，中別府雄作
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化損傷塩基の修復機構は生殖細胞ゲノム変異を抑制し同系交配によるマウスの表現型の安定性に寄与する.2012
- Author(s)
  大野みずき，作見邦彦，福村龍太郎，権藤洋一，續輝久，中別府雄作
- Organizer
  日本環境変異学会第41回大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Mechanism of genome instability triggered by deoxyinosine nucleotides.2012
- Author(s)
  Abolhassani N, Iyama T, Tsuchimoto D, Sakumi K, Nakabeppu Y, Samson LD
- Organizer
  7th Annual CEHS Poster Session
- Place of Presentation
  Cambridge, MA, USA
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Cytotoxic effects of X-ray irradiation on proliferative and differentiated human neuroblastoma cell line, SH-SY5Y, and modulation by neurotrophic factors and CDK5 inhibitor.2012
- Author(s)
  Erika Castillo, Julio Leon, Yoriko Akimoto, Yasuto Yoneshima, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-Oxoguanine in brain causes complex neurodegeneration through DNA repair.2012
- Author(s)
  Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi and Yusaku Nakabeppu
- Organizer
  The 9th ASMRM and Chinese Mit'2012
- Place of Presentation
  Beijing, China
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Cooperative neuroprotection by insulin and neurotrophic factors.2012
- Author(s)
  Julio Leon, Masaaki Hokama, Sugako Oka, Erika Castillo, Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Mechanism of genome instability triggered by deoxyinosine nucleotides and defense systems in mammalian cells.2012
- Author(s)
  Daisuke Tsuchimoto, Teruaki Iyama, Nona Abolhassani, Yasuto Yoneshima, Kunihiko Sakumi, Naoko Shiomi, Masahiko Mori, Tadahiro Shiomi, Tetsuo Noda and Yusaku Nakabeppu
- Organizer
  4th US-JAPAN DNA REPAIR MEETING
- Place of Presentation
  Virginia, USA
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Obesity and altered expression of genes related to Diabetes-mellitus in Alzheimer’s disease mouse model.2012
- Author(s)
  Sugako Oka, Masaaki Hokama, Julio Leon, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Mice lacking fosB display impaired adult hippocampal neurogenesis and spontaneous epilepsy2012
- Author(s)
  Noriko Yutsudo, Takashi Kamada, Hiroko Nomaru, Yoko H.Ohnishi, Yoshinori N.Ohnishi, Kosuke Kajitani, Kunihiko Sakumi, Hiroshi Shigeto, Yusaku Nakabeppu
- Organizer
  The 21^<st> Hot spring Harbor Symposium jointly with 8^<th> Global COE International Symposium, Young Investigators Presentation
- Place of Presentation
  Fukuoka
- Year and Date
  2012-01-21
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] fosB遺伝子産物によるアナフィラトキシンC5a 走化性受容体遺伝子C5arとGpr77の発現制御機構の解析.2012
- Author(s)
  能丸寛子，作見邦彦，土本大介，中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Obesity and altered expression of genes related to diabetes mellitus in a transgenic mouse model of Alzheimer's disease.2012
- Author(s)
  Sugako Oka, Masaaki Hokama, Julio Leon, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 2-OH-ATP as a signal molecule for the oxidative stress in mammalian cells。2012
- Author(s)
  Eiko Ohta, Kunihiko Sakumi, Daisuke Tsuchimoto, Yuka Takiguchi and Yusaku Nakabeppu
- Organizer
  The 8th 3R Symposium (International Symposium on DNA Replication, Recombination and Repair)
- Place of Presentation
  The 8th 3R Symposium (International Symposium on DNA Replication, Recombination and Repair)
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] MUTYHはp53による発がん抑制のメディエータである.2012
- Author(s)
  岡素雅子，レオンフリオ，土本大介，作見邦彦，中別府雄作
- Organizer
  第35回日本がん疫学・分子疫学研究会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Alzheimer’s disease mouse model exhibits altered expression of genes related to diabetes-mellitus with obesity.2012
- Author(s)
  Sugako Oka, Masaaki Hokama, Julio Leon, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 哺乳動物のITP 分解酵素とエンドヌクレアーゼV.2012
- Author(s)
  作見邦彦，土本大介，中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 活性酸素による核酸の修飾とゲノム応答の遺伝学.2012
- Author(s)
  中別府雄作，土本大介，盛子敬，岡素雅子，作見邦彦
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] イノシン三リン酸によるゲノム不安定化機構と細胞内イノシン三リン酸生成経路の解明.2012
- Author(s)
  米嶋康臣，土本大介，作見邦彦，中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Base excision repair by MUTYH initiates calpain/PARP-dependent neurodegeneration under oxidative stress.2012
- Author(s)
  Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 筋萎縮性側索硬化症におけるGalectin-1の病態への関与.2012
- Author(s)
  小早川優子，作見邦彦，中別府雄作
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] DNA中のデオキシイノシン量を制御するメカニズム.2012
- Author(s)
  作見邦彦，中別府雄作
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 活性分子種による核酸の化学修飾と生体応答2011
- Author(s)
  中別府雄作, 猪山輝昭, 岡素雅子, 盛子敬, 作見邦彦, 土本大介
- Organizer
  第2回 Molecular Cardiovascular Conference
- Place of Presentation
  余市(招待講演)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Fosb products regulate proliferation of adult hippocampal neural progenitor cells and suppress spontaneous epileptic seizures2011
- Author(s)
  Noriko Yutsudo, Takashi Kamada, Hiroko Nomaru, Yoko H.Ohnishi, Yoshinori N.Ohnishi, Kosuke Kajitani, Kunihiko Sakumi, Hiroshi Shigeto, Yusaku Nakabeppu
- Organizer
  2011 International Summer Conference for Neurons and Brain Disease
- Place of Presentation
  Toyama
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] ほ乳動物細胞におけるデオキシイノシンヌクレオチドによるゲノム不安定化とその防御機構2011
- Author(s)
  土本大介, 猪山輝昭, アボルハッサニノナ, 米嶋康臣, 作見邦彦, 中別府雄作
- Organizer
  日本遺伝学会第83回大会
- Place of Presentation
  京都
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Roles of insulin in survival and proliferation of SH-SY5Y neuroblastoma cells under neuronal differentiation2011
- Author(s)
  Julio Leon, Masaaki Hokama, Sugako Oka, Erika Castillo, Kunihiko Sakumi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-OxoguanineはDNA鎖切断を誘発することで減数分裂期の相同染色体組換え頻度を上昇させる2011
- Author(s)
  大野みずき, 作見邦彦, 古市正人, 中西恵美, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第83回大会
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] MUTYHはp53による発がん抑制のメディエータである2011
- Author(s)
  岡素雅子, レオンフリオ, 作見邦彦, 土木大介, 中別府雄作
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 2-OH-ATP as a candidate molecule for the oxidative stress sensor in mammalian cells2011
- Author(s)
  Kunihiko Sakumi, Eiko Ohta, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化ヌクレオチド2-OH-ATPによる細胞死の制御機構2011
- Author(s)
  太田詠子, 土本大介, 作見邦彦, 瀧口友香, 中別府雄作
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] ΔFosB and/or Δ2ΔFosB regulate proliferation of adult hippocampal neural progenitor cells and suppress spontaneous epileptic seizures2011
- Author(s)
  Noriko Yutsudo, Takashi Kamada, Hiroko Nomaru, Yoko H.Ohnishi, Yoshinori N.Ohnishi, Kosuke Kajitani, Kunihiko Sakumi, Hiroshi Shigeto, Yusaku Nakabeppu
- Organizer
  Neurogenesis 2011
- Place of Presentation
  Kobe
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Mechanism of genome instability triggered by deoxyinosine nucleotides and defense systems in mammalian cells2011
- Author(s)
  Daisuke Tsuchimoto, Teruaki Iyama, Nona Abolhassani, Yasuto Yoneshima, Kunihiko Sakumi, Naoko Shiomi, Masahiko Mori, Tadahiro Shiomi, Yusaku Nakabeppu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] MUTYHはp53による発がん抑制のメディエータである2011
- Author(s)
  岡素雅子, フリオレオン, 作見邦彦, 土本大介, 中別府雄作
- Organizer
  第40回日本環境変異原学会シンポジウム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Ogg1, Mth1, Mutyh triple knockout mouseの樹立と解析2011
- Author(s)
  作見邦彦, 大野みずき, 田口健一, 外間政朗, 中別府雄作
- Organizer
  「個体レベルでの発がん研究支援活動」ワークショップ
- Place of Presentation
  大津
- Year and Date
  2011-02-03
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] ΔFosB/Δ2ΔFosBは成体海馬神経前駆細胞の増殖制御とてんかん自然発症の抑制に働く2011
- Author(s)
  湯通堂紀子, 鎌田崇嗣, 能丸寛子, 大西(本田)陽子, 大西克典, 梶谷康介, 作見邦彦, 重藤寛史, 中別府雄作
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Defects of DNA repair systems against oxidative mutagenesis : implication in oxidative-stress induced carcinogenesis2011
- Author(s)
  Yoshimichi Nakatsu, Jing Shu Piao, Takuro Isoda, Kunihiko Sakumi, Yusaku Nakabeppu, Teruhisa Tsuzuki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化ストレスはDNA修復酵素MUTYHに依存して神経変性を引き起こす2011
- Author(s)
  盛子敬, 岡素雅子, 土本大介, 作見邦彦, 中別府雄作
- Organizer
  第4回Kyushu CVD Conference
- Place of Presentation
  福岡(招待講演)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 酸化ヌクレオチド2-OH-ATPによる細胞死の制御機構2010
- Author(s)
  太田詠子, 土本大介, 作見邦彦, 中別府雄作
- Organizer
  B20B2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Deoxyinosine incorporated into DNA under ITPA deficiency2010
- Author(s)
  Nona Abolhassani, Teruaki Iyama, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  日本遺伝学会第82回大会
- Place of Presentation
  札幌
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 環境ストレスによるヌクレオチドプールの恒常性破綻の分子病態2010
- Author(s)
  中別府雄作, 猪山輝昭, Nona Abolhassani, 太田詠子, 盛子敬, 岡素雅子, 作見邦彦, 土本大介
- Organizer
  日本遺伝学会第82回大会
- Place of Presentation
  札幌
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Quality control in the purine nucleotide pools is essential for maintaining genomic integrity in mammals.2010
- Author(s)
  Yusaku Nakabeppu, Nona Abolhassani, Teruaki Iyama, Zijing Sheng, Sugako Oka, Kunihiko Sakumi, Daisuke Tsuchimoto
- Organizer
  The 7th 3R (Replication, Recombination and Repair) Symposium
- Place of Presentation
  Toyama, Japan
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] The biological significance of ITPA protein and its substrates, ITP and dITP in mouse2010
- Author(s)
  Kunihiko Sakumi, Nona Abolhassani, Mehrdad Behmanesh, Teruaki Iyama, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  B20B2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.2010
- Author(s)
  Nona Abolhassani, Teruaki Iyama, Daisuke Tsuchimoto, Kunihiko Sakumi, Mizuki Ohno, Mehrdad Behmanesh, Yusaku Nakabeppu
- Organizer
  The 7th 3R (Replication, Recombination and Repair) Symposium
- Place of Presentation
  Toyama, Japan
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.2010
- Author(s)
  Nona Abolhassani, Teruaki iyama, Daisuke Tsuchimoto, Kunihiko Sakumi, Mizuki Ohno, Mehrdad Behmanesh, Yusaku Nakabeppu
- Organizer
  Gordon Research Conference on DNA Damage, Mutation and Cancer
- Place of Presentation
  Ventura, CA, USA
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Oxidative stress-induced tumorigenesis in the small intestines of DNA repair-deficient mice2010
- Author(s)
  Teruhisa Tsuzuki, Jing Shu Piao, Takuro Isoda, Kunihiko Sakumi, Yusaku Nakabeppu, Yoshimichi Nakatsu
- Organizer
  Bond Workshop : Biological effects of low-level exposure to ionizing radiation, health risks and clinical consequences
- Place of Presentation
  Richland, Washington, USA
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-22241013
[Presentation] Mitochondrial toxin, 3-nitropropionic acid induces striatal degeneration through the two distinct MUTYH-dependent cell death pathways.2010
- Author(s)
  Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  The 7th 3R (Replication, Recombination and Repair) Symposium
- Place of Presentation
  Toyama, Japan
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-oxoguanineはDNA 鎖切断を誘発することで減数分裂期の相同染色体組換え頻度を上昇させる2010
- Author(s)
  大野みずき, 作見邦彦, 續輝久, 中別府雄作
- Organizer
  B20B2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 環境ストレスによるヌクレオチドプールの恒常性破綻に起因するゲノム障害とその防御機構2010
- Author(s)
  中別府雄作, Nona Abolhassani, 猪山輝昭, 太田詠子, 盛子敬, 岡素雅子, 土本大介, 作見邦彦
- Organizer
  B20B2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Poor proliferation of neural progenitors in the dentate gyrus of hippocampus in adult fosB-null mice exhibiting increased susceptibility for spontaneous epileptic seizures2009
- Author(s)
  Niriko YUTSUDO, Takashi KAMADA, Yoko HONDA-OHNISHI, Yoshinori OHNISHI, Kosuke KAJITANI, Kunihiko SAKUMI, 他
- Organizer
  Neurogenesis 2009 "Hippocamal neurogenesis : its implication in neural functions and mental diseases
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Poor proliferation of neural progenitors in the dentate gyrus of hippocampus in adult fosB-null mice exhibiting increased susceptibility for spontaneous epileptic seizures2009
- Author(s)
  Noriko Yutsudo, Takashi Kamada, Yoko Honda-Ohnishi, Yoshinori Ohnishi, Kosuke, Kajitani, Kunihiko Sakumi, 他
- Organizer
  第32回日本神経科学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] 酸化的DNA損傷と生殖細胞ゲノム変異2009
- Author(s)
  大野みずき、作見邦彦、古市正人、續輝久、中別府雄作
- Organizer
  日本環境変異原学会第38回大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Base excision repair-mediated programmed cell death responsible for tumor suppression and neurodegeneration2009
- Author(s)
  Yusaku Nakabeppu, Sugako Oka, Zijing Sheng, Daisuke Tsuchimo to, Kunihiko Sakumi
- Organizer
  4th International Workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Okinawa
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Oxidative Stress-Induced Tumorigenesis in the Small Intestine of Various DNA Repair-Deficient Mice2009
- Author(s)
  Teruhisa Tsuzuki, Jingshu Piao, Takuro Isoda, Kunihiko Sakumi, 他
- Organizer
  The 3rd ASM Conference on DNA Repair and Mutagenesis : From Molecular Structure to Human Disease
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Poor proliferation of neural progenitors in the dentate gyrus of hippocampus in adult fosB-null mice exhibiting increased susceptibility for spontaneous epileptic seizures2009
- Author(s)
  Noriko YUTSUDO, Takashi KAMADA, Yoko HONDA-OHNISHI, Yoshinori OHNISHI, Kosuke KAJITANI, Kunihiko SAKUMI, 他
- Organizer
  Kyushu Brain Days 2009, International Student Symposium
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Characterization of ITPase knockout mouse.2009
- Author(s)
  Kunihiko Sakumi, Nona Abolhassani, Sugako Oka, 他
- Organizer
  The 3rd ASM Conference on DNA Repair and Mutagenesis : From Molecular Structure to Human Disease
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] 8-Oxoguanine promotes base substitution and homologous recombination in mammalian germ cells.2009
- Author(s)
  Mizuki Ohno, Masato Furuichi, Kunihiko Sakumi, 他
- Organizer
  The 3rd ASM Conference on DNA Repair and Mutagenesis : From Molecular Structure to Human Disease
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] 酸化損傷塩基の修復能を欠損するマウスにおける継世代的影響の解析2009
- Author(s)
  大野みずき、作見邦彦、古市正人、續輝久、中別府雄作
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] 酸化的DNA損傷と生殖細胞ゲノム変異2009
- Author(s)
  大野みずき、作見邦彦、古市正人、續輝久、中別府雄作
- Organizer
  日本放射線影響学会第52回大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] MUTYH, A MOLECULAR SWITCH FOR PROGRAMMED CELL DEATH AND TUMOR SUPPRESSION2009
- Author(s)
  Sugako Oka, Mizuki Ohno, Daisuke Tsuchimoto, Kunihiko Sakumi, Yusaku nakabeppu
- Organizer
  The Fortieth International Symposium of The Princess Takamatsu Cancer research Fund
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] Production and analysis of the Oggl, Mthl, Mutyh triple knockout mouse strain2009
- Author(s)
  Kunihiko Sakumi, Mizuki Ohno, Ken-ichi Taguchi, Masaaki Hokama, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] An increased expression of NUDT16 with IDP/dIDP hydrolyzing activity in immortalized IPTA-null mouse embryonic fibroblasts suppresses ITPA-deficient phenotypes.2009
- Author(s)
  Nona Abolhassani, Teruaki Iyama, Daisuke Tsuchimoto, Kunihiko Sakumi, Mizuki Ohno, Mehrdad Behmanesh, Yusaku Nakabeppu
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20012038
[Presentation] ITPA knockout mice2007
- Author(s)
  Sakumi, K
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-19651097
[Presentation] ITPA knockout mice.2007
- Author(s)
  Sakumi, K
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-18012035
[Presentation] 放射線照射によって生成される損傷プリンヌクレオシドの同定と定量
- Author(s)
  秋本頼子, Nona Abolhassani, Erika Castillo, 岡素雅子, 土本大介, 作見邦彦, 中別府雄作
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] 8-oxoguanine に起因するde novo germline mutation の解析
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩﨑裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Role of the oxidative DNA damage repair system in somatic and germline mutations in mice
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu,Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  Zing conference Genomic integlity
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-01 – 2015-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Accumulation of deoxyinosine triphosphate induces mismatch repair-dependent cell growth arrest and instability of genomic DNA.
- Author(s)
  Yasuto Yoneshima, Daisuke Tsuchimoto, Nona Abolhassani, Teruaki Iyama, Kunihiko Sakumi, Naoko Shiomi, Masahiko Mori, Tadahiro Shiomi, Yusaku Nakabeppu
- Organizer
  International Symposium between Kyushu University Post-Global Centers of Excellence Program and School of Biomedical Sciences, Monash University
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Oxidation of nucleic acids by reactive oxygen species and control mechanisms of genetic diversity in mammals.
- Author(s)
  Yusaku Nakabeppu, Mizuki Ohno, Kunihiko Sakumi
- Organizer
  International Symposium between Kyushu University Post-Global Centers of Excellence Program and School of Biomedical Sciences, Monash University
- Place of Presentation
  Melbourne, Australia
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Influence of oxidative DNA damage on the rate of somatic and germline mutation
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu,Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-25 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer’s disease model mice
- Author(s)
  岡素雅子, Julio Leon, 加藤木敦央, Erika Castillo, Nona Abolhassani, 作見邦彦, 井手友美, 康東天, 中別府雄作
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Fosb遺伝子産物はマクロファージにおける補体C5a受容体遺伝子，C5ar1とC5ar2の発現を制御する
- Author(s)
  森岡紀子, 能丸寛子, 作見邦彦, 土本大介, 中別府雄作
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Microglial activation by Fosb gene.
- Author(s)
  Hiroko Nomaru, Kunihiko Sakumi, Atsuhisa Katogi, Yoshinori N Ohnishisi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  International Symposium between Kyushu University Post-Global Centers of Excellence Program and School of Biomedical Sciences, Monash University
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Control mechanisms of genetic diversity and programed cell death induced by 8-oxoguanine in mammals
- Author(s)
  Yusaku Nakabeppu, Mizuki Ohno, Sugako Oka, Zijing Sheng, Kunihiko Sakumi
- Organizer
  9th ３R (Replication, Repair, recombination) symposium
- Place of Presentation
  御殿場
- Year and Date
  2014-11-11 – 2014-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] MUTYH-dependent programed cell death induced by 8-oxoguanine accumulated in cellular DNAs and its implication in tumorigenesis and neruodegeneration
- Author(s)
  Yusaku Nakabeppu, Sugako Oka, Zijing Sheng, Kunihiko Sakumi
- Organizer
  5th US-Japan DNA Repair Meeting
- Place of Presentation
  鳴門
- Year and Date
  2014-10-28 – 2014-10-31
- Invited
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Analysis of Fosb(F/F) mice expressing only FOSB and vFOSB but not ΔFOSB and Δ2ΔFOSB
- Author(s)
  Atsuhisa Katogi, Hiroko Nomaru, Yoshinoro Ohnishi, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] DNA酸化損傷修復欠損マウスの継代実験で捉えられた遺伝現象
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩﨑裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia
- Author(s)
  Hiroko Nomaru, Kunihiko Sakumi, Atsuhisa Katogi, Daisuke Tsuchimoto, Yusaku Nakabeppu
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Analysis of FosbF/F mice expressing only FOSB and vFOSB.
- Author(s)
  Atsuhisa Katogi, Hiroko Nomaru, Yoshinori N. Ohnishi, Kunihiko Sakumi, Yusaku Nakabeppu
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer’s disease model mice
- Author(s)
  Sugako Oka, Julio Leon, Atsuhisa Katogi, Kunihiko Sakumi, Tomomi Ide, Dongchon Kang, Yusaku Nakabeppu
- Organizer
  International Meeting on Mitochondrial Pathology
- Place of Presentation
  Tampere，Finland
- Year and Date
  2014-06-15 – 2014-06-19
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] デオキシイノシン三リン酸の蓄積はミスマッチ修復タンパク質MLH1に依存した細胞周期の遅延をもたらす
- Author(s)
  土本大介, 米嶋康臣, Nona Abolhassani, 猪山輝昭, 作見邦彦, 塩見尚子, 森雅彦, 塩見忠博, 野田哲生, 中別府雄作
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] ほ乳動物ゲノムにおける8-オキソグアニンの修復プロセッシングと細胞運命
- Author(s)
  岡素雅子, 盛子敬, 作見邦彦, 中別府雄作
- Organizer
  第37回日本分子生物学会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22221004
[Presentation] Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer’s disease model mice
- Author(s)
  岡素雅子, Julio Leon, 加藤木敦央, 作見邦彦, 井手友美, 康東天, 中別府雄作
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  福岡
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-22221004

1. NAKABEPPU YUSAKU (30180350)

# of Collaborated Projects: 10 results

# of Collaborated Products: 123 results
2. SEKIGUCHI Mutsuo (00037342)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. TSUZUKI Teruhisa (40155429)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
4. HAYAKAWA Hiroshi (70150422)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. TSUCHIMOTO Daisuke (70363348)

# of Collaborated Projects: 3 results

# of Collaborated Products: 71 results
6. OKA Sugako (80467894)

# of Collaborated Projects: 3 results

# of Collaborated Products: 51 results
7. SANADA Masayuki (40084264)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. Ohno Mizuki (70380524)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
9. TOMINAGA Youhei (90304823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SHENG Zijing (90467895)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
11. SHIMOKAWA Hidetoshi (50122792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. FURUICHI Masato (70199420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
13. NAKATSU Yoshimichi (00207820)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. AKIMOTO Yoriko (50613254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. OHYAGI Yasumasa (30301336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SHIMIZU Kenji (10037286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ITO Riyoko (10140865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KURA Shinobu (90037391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKAGI Yasumitsu (20212003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MAKI Hisaji (20199649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 池永満生 (70025378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 許南浩 (70173573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 峯浦一喜 (70134103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 綾木仁 (80222701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 日高京子 (00216681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 手島康介 (20447593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. DEMPLE Bruce

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. DAVID Ludlum

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. MICHAEL Volk

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. VOLKERT Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. LUDLUM David B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. VOLKERT Mich

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MATIJASEVIC ゼンカ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. ROBERTSON Ge

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. RIABOWOL Kar

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. RANCOURT Der

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 岩城徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 豊國伸哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 国定充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKUMI Kunihiko 作見 邦彦

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An attempt to quantify and evaluate the effect of in vitro fertilization on the genomic information of offspringPrincipal Investigator

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Clarification of the mechanism of germline mutation occurrence that causes familial tumorPrincipal Investigator

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プリンヌクレオチドの酸化と脱アミノ化に起因する突然変異と発がんPrincipal Investigator

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「ITPaseによるATPプールの品質維持機構」に普遍性はあるかPrincipal Investigator

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プリンヌクレオチドの脱アミノ化に起因する突然変異と発がんPrincipal Investigator

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Molecular mechanism of development and repression of lung tumor in OGG1 knockout mousePrincipal Investigator

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DNA修復酵素遺伝子欠損マウスを用いた発癌抑制機構の解析Principal Investigator

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発癌抑制に果たすDNA修復酵素の役割Principal Investigator

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Biological phenomena caused by 8-oxoguanine in DNAPrincipal Investigator

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SAKUMI Kunihiko 作見邦彦