Adachi Takeshi 足立健

… Alternative Names

ADACHI Takeshi 足立健

ADACHI Ken 足立健

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Researcher Number	50231931
External Links
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 内科学, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 内科学, 教授 2014: 防衛医科大学校, 循環器内科, 教授 2012: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 教授 2012: 防衛医科大学校, 医学教育学部医学科専門課程, 教授 2011 – 2012: 防衛医科大学校, 医学教育部・医学科専門課程, 教授 … More 2010: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部・医学科専門課程, 准教授 2008 – 2009: Keio University, 医学部, 講師 2007: Keio University, 医学部, 准教授 2005 – 2006: 慶應義塾大学, 医学部, 専任講師 1994: Keio University, School of Medicine, Director, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Pathological medical chemistry Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Basic Section 55050:Anesthesiology-related / Circulatory organs internal medicine / Circulatory organs internal medicine / Neuroscience in general
Keywords	Principal Investigator メタボリックシンドローム / インスリン / ２型糖尿病 / 脂質代謝 / 臓器連関 / 酸化ストレス / 脂肪分化 / 肥満 / 血管内皮障害 / 2型糖尿病 … More / 腎機能障害 / 活性酸素種 / 内皮依存性血管拡張 / インスリン抵抗性 / 一酸化窒素 / ミトコンドリア / 脂肪肝 / 血管内皮機能 / 異所性脂肪沈着 / Insulin / ERK2 / 脂肪細胞 / 血管内皮細胞 / プロテオミクス / メタボリック・シンドローム / 分子病態学 … More Except Principal Investigator 血管内皮細胞 / 糖尿病 / 血管内皮機能 / インスリン抵抗性 / 血管内皮機能障害 / NO / NADH / 心筋虚血 / 細胞内情報伝達 / 一酸化窒素 / ミトコンドリア / transcriptome / endothelial cell / パルミチン酸 / O-GlcNAc / 血管 / 動脈硬化 / Palmitic acid / O-GlcNAｃ / 代謝 / 神経毒性 / 小児 / 全身麻酔薬 / AMP キナーゼ / C-ペプチド / Erf2 / type 2 diabetes / High fat diet / Nrf2 / Autophagy / Doxorubicin / C-peptide / 内皮機能 / 活性酸素種 / 血管内皮障害 / 脂肪肝 / 二型糖尿病 / プロスタノイド / 酸化ストレス / 肥満 / 血管収縮因子 / 肺高血圧 / ERK2 / 2型糖尿病 / メタボリックシンドローム / インスリン / 生体分子 / 細胞・組織 / 内科 / 循環器・高血圧 / 糖尿病性血管障害 / グルコサミン / L-NAME / right ventricle / cathecolamine / coronary circulation / myocardial ischemia / shock / 乳酸 / NAOH / 気酸 / 冠循環 / ショック / BKCaチャネル / カルシウム / BKCa / ストレス / シグナル伝達 / 老化 / 補体 / 遺伝子発現 / 再灌流傷害 / SIRT1 / sirtuin / 脱アセチル化 / 電子伝達系 / 心保護 / カロリー制限 / 記憶・学習 / 育児 / 自閉症 / 分化・増殖 / 神経幹細胞 / 神経 / ERK / グルタチオン / 生体情報工学 / Hypoxia inducible factor / 構造生物学 / cytochrome oxidase / メタボローム / 酸素センサー / ガスバイオロジー / 一酸化炭素 Less

Elucidation of the relationship between diabetes and chronic vascular inflammation by transcriptome analysis using the great saphenous vein
- Principal Investigator
  
  眞崎暢之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
発達期の脳における全身麻酔薬の神経毒性メカニズムの解明
- Principal Investigator
  
  佐藤泰司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
Mechanism of palmitic acid-induced diabetic endothelial dysfunction via O-GlcNAc
- Principal Investigator
  
  MASAKI NOBUYUKI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
Eucidation of signaling by Cpeptide and application for cardiovascular disease
- Principal Investigator
  
  Ido Yasuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
Role of ERK2 in Ectopic Fat deposition and Cardiovascular Complications of Type II DiabetesPrincipal Investigator
- Principal Investigator
  
  Adachi Takeshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
Evaluation of the effects of glucosamine modification on endothelial cells of diabetic angiopathy
- Principal Investigator
  
  Masaki Nobuyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Defense Medical College
Vascular/organ association via ERK2 in insulin resistance
- Principal Investigator
  
  Takayuki Namba
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Defense Medical College
Investigation of physiological role of cardiac BKCa channel and its practical application for medical treatment
- Principal Investigator
  
  YADA Hirotaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Defense Medical College
Study for the Function of ERK2 in the Brain Using ERK2 Conditional Knockout Mouse
- Principal Investigator
  
  SATOH Yasushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  防衛医科大学校
   National Defense Medical College
Evaluation of mechanisms by which caloric restriction regulates mitochondrial function
- Principal Investigator
  
  SHINMURA Ken
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University
Post-translational ,protein modification induced with reactive species in metabolic syndromePrincipal Investigator
- Principal Investigator
  
  ADACHI Takeshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University
Biomedical Application of Gas Biology through Multidisciplinary Approaches
- Principal Investigator
  
  SUEMATSU Makoto
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Keio University
Characterization of Myocardial Ischemia in Shock by NADH Fluorescence
- Principal Investigator
  
  HORI Shingo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University

[Book] 細胞学 vol 25(2) 161-1652006
- Author(s)
  末松誠, 梶村真弓, 足立健
- Publisher
  ヘムオキシゲナーゼ-CO系による血管機能制御機構とNOシステムとの相互作用
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality2023
- Author(s)
  Ishinoda Yuki、Masaki Nobuyuki、Hitomi Yasuhiro、Taruoka Akira、Kawai Akane、Iwashita Midori、Yumita Yusuke、Kagami Kazuki、Yasuda Risako、Ido Yasuo、Toya Takumi、Ikegami Yukinori、Namba Takayuki、Nagatomo Yuji、Miyazaki Koji、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 30 Issue: 10 Pages: 1364-1375
- DOI
  10.5551/jat.63779
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2023-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Risk factors for early atherosclerotic changes in the retinal arterioles in healthy middle-aged men2023
- Author(s)
  Mine Masataka、Masaki Nobuyuki、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  Vascular Failure
  
  Volume: 7 Issue: 1 Pages: 24-28
- DOI
  10.30548/vascfail.7.1_24
- ISSN
  2432-4477
- Year and Date
  2023-12-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Association between Smoking and Urine Indole Levels Measured by a Commercialized Test2022
- Author(s)
  Mine Masataka、Masaki Nobuyuki、Toya Takumi、Namba Takayuki、Nagatomo Yuji、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  Metabolites
  
  Volume: 12 Issue: 3 Pages: 234-234
- DOI
  10.3390/metabo12030234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Sarco/Endoplasmic Reticulum Ca2+ ATPase 2 Activator Ameliorates Endothelial Dysfunction; Insulin Resistance in Diabetic Mice2022
- Author(s)
  2)Kimura T, Kagami K, Sato A, Osaki A, Ito K, Horii S, Toya T, Masaki N, Yasuda R, Nagatomo Y, Adachi T.
- Journal Title
  
  Cells: Cellular Metabolism 2022 in press
  
  Volume: XXX
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02815
[Journal Article] Association of serum nitric oxide metabolite level with mortality in patients undergoing coronary angiography2022
- Author(s)
  Namba Takayuki、Masaki Nobuyuki、Hitomi Yasuhiro、Ishinoda Yuki、Iwashita Midori、Yumita Yusuke、Kagami Kazuki、Yasuda Risako、Ikegami Yukinori、Toya Takumi、Nagatomo Yuji、Takase Bonpei、Soejima Kyoko、Adachi Takeshi
- Journal Title
  
  Journal of Cardiology
  
  Volume: 80 Issue: 6 Pages: 578-584
- DOI
  10.1016/j.jjcc.2022.07.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Effectiveness of the d-ROMs oxidative stress test to predict long-term cardiovascular mortality.2022
- Author(s)
  Hitomi Y, Masaki N, Ishinoda Y, Ido Y, Iwashita M, Yumita Y, Kagami K, Yasuda R, Ikegami Y, Toya T, Namba T, Nagatomo Y, Takase B, Adachi T
- Journal Title
  
  Int J Cardiol
  
  Volume: 354 Pages: 43-47
- DOI
  10.1016/j.ijcard.2022.03.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-20K08503
[Journal Article] Deletion of Superoxide Dismutase 1 Blunted Inflammatory Aortic Remodeling in Hypertensive Mice under Angiotensin II Infusion2021
- Author(s)
  Shiraishi Yasunaga、Ishigami Norio、Kujiraoka Takehiko、Sato Atsushi、Fujita Masanori、Ido Yasuo、Adachi Takeshi
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 3 Pages: 471-471
- DOI
  10.3390/antiox10030471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17204, KAKENHI-PROJECT-18H02815
[Journal Article] Effectiveness of pulsatility index of carotid Doppler ultrasonography to predict cardiovascular events2021
- Author(s)
  Hitomi Yasuhiro、Masaki Nobuyuki、Ishinoda Yuki、Kagami Kazuki、Yasuda Risako、Toya Takumi、Namba Takayuki、Nagatomo Yuji、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  Journal of Medical Ultrasonics
  
  Volume: 49 Issue: 1 Pages: 95-103
- DOI
  10.1007/s10396-021-01164-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling2020
- Author(s)
  Teratani Toshiaki、Tomita Kengo、Toma-Fukai Sachiko、Nakamura Yutaro、Itoh Toshimasa、Shimizu Hikaru、Shiraishi Yasunaga、Sugihara Nao、Higashiyama Masaaki、Shimizu Takahiko、Inoue Ikuo、Takenaka Yasuhiro、Hokari Ryota、Adachi Takeshi、Shimizu Toshiyuki、Miura Soichiro、Kanai Takanori
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 156 Pages: 45-56
- DOI
  10.1016/j.freeradbiomed.2020.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17204, KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-20H03583, KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18K07924
[Journal Article] Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study2020
- Author(s)
  Toya Takumi、Ito Kei、Kagami Kazuki、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Horii Shunpei、Yasuda Risako、Namba Takayuki、Ido Yasuo、Nagatomo Yuji、Hayashi Katsumi、Masaki Nobuyuki、Yada Hirotaka、Adachi Takeshi
- Journal Title
  
  IJC Heart & Vasculature
  
  Volume: 26 Pages: 100437-100437
- DOI
  10.1016/j.ijcha.2019.100437
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
[Journal Article] The association of insulin-induced eNOS activation in freshly isolated arterial endothelial cells with cardio-ankle vascular index2019
- Author(s)
  5)Nobuyuki Masaki, Yasuo, Ido, Adachi T et al.
- Journal Title
  
  JAHA
  
  Volume: 19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02815
[Journal Article] Computed tomography-measured pulmonary artery to aorta ratio and EUTOS score for detecting dasatinib-induced pulmonary arterial hypertension2019
- Author(s)
  Toya Takumi、Nagatomo Yuji、Kagami Kazuki、Yukino Midori、Yasuda Risako、Namba Takayuki、Ido Yasuo、Kobayashi Shinichi、Masaki Nobuyuki、Yada Hirotaka、Kimura Fumihiko、Adachi Takeshi
- Journal Title
  
  The International Journal of Cardiovascular Imaging
  
  Volume: 35 Issue: 8 Pages: 1435-1442
- DOI
  10.1007/s10554-019-01548-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
[Journal Article] Arterial Stiffness Assessed by Cardio-Ankle Vascular Index2019
- Author(s)
  Namba Takayuki、Masaki Nobuyuki、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 15 Pages: 3664-3664
- DOI
  10.3390/ijms20153664
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-17K09565
[Journal Article] Endothelial Insulin Resistance of Freshly Isolated Arterial Endothelial Cells From Radial Sheaths in Patients With Suspected Coronary Artery Disease2019
- Author(s)
  Nobuyuki Masaki, Yasuo Ido, Toshiyuki Yamada, Youhei Yamashita, Takumi Toya, Bonpei Takase, Naomi M. Hamburg, Takeshi Adachi
- Journal Title
  
  Journal of American Heart Association
  
  Volume: 8 Issue: 6
- DOI
  10.1161/jaha.118.010816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09565, KAKENHI-PROJECT-18H02815
[Journal Article] Production of adeno-associated virus vectors for in vitro and in vivo applications2019
- Author(s)
  Kimura Toyokazu、Ferran Beatriz、Tsukahara Yuko、Shang Qifan、Desai Suveer、Fedoce Alessandra、Pimentel David Richard、Luptak Ivan、Adachi Takeshi、Ido Yasuo、Matsui Reiko、Bachschmid Markus Michael
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 13601-13601
- DOI
  10.1038/s41598-019-49624-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Journal Article] A Rare Case of Rush Progression of Purulent Pericarditis by <i>Escherichia coli</i> in a Patient with Malignant Lymphoma2018
- Author(s)
  Horii Shunpei、Yada Hirotaka、Ito Kei、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Yasuda Risako、Toya Takumi、Namba Takayuki、Masaki Nobuyuki、Adachi Takeshi
- Journal Title
  
  Int. Heart J.
  
  Volume: 59 Issue: 3 Pages: 655-659
- DOI
  10.1536/ihj.17-238
- NAID
  130007378304
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2018-05-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09596
[Journal Article] Preserved Vasoconstriction and Relaxation of Saphenous Vein Grafts Obtained by a No-Touch Technique for Coronary Artery Bypass Grafting2018
- Author(s)
  Yamada T, Adachi T, Ido Y, Masaki N, Toya T, Uchimuro T, Nishigawa K, Suda H, Osako M, Yamazaki M, Takanashi S, Shimizu H
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 1 Pages: 232-238
- DOI
  10.1253/circj.CJ-18-0714
- NAID
  130007550528
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-12-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09565, KAKENHI-PROJECT-18H02815
[Journal Article] Effect of Oral Branched-Chain Amino Acids on Serum Albumin Concentration in Heart Failure Patients with Hypoalbuminemia: Results of a Preliminary Study2018
- Author(s)
  Uchino Yuichi、Watanabe Masafumi、Takata Munenori、Amiya Eisuke、Tsushima Kensuke、Adachi Takeshi、Hiroi Yukio、Funazaki Toshikazu、Komuro Issei
- Journal Title
  
  American Journal of Cardiovascular Drugs
  
  Volume: 18 Issue: 4 Pages: 327-332
- DOI
  10.1007/s40256-018-0269-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09488, KAKENHI-PROJECT-18H02815
[Journal Article] 心血管病におけるSERCA2の障害2018
- Author(s)
  1)足立　健、木村　豊和、東谷　卓美、伊藤　桂、長友　祐司、矢田　浩崇
- Journal Title
  
  最新医学
  
  Volume: 第73巻 Pages: 68-73
- Data Source
  KAKENHI-PROJECT-18H02815
[Journal Article] Suppresion of Rad leads to arrhythmogenesis via PKA-mediated phosphorylation of ryanodine receptor activity in the heart2014
- Author(s)
  Yamakawa H, Murata M, Suzuki T, Yada H, ishida H, Aizawa Y, Adachi T, Kamiya K, Fukuda K.
- Journal Title
  
  Biochemical and Biophysiological Research Communications
  
  Volume: 452 Pages: 701-707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860629
[Journal Article] Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain2012
- Author(s)
  Shinmura K, Tamaki K, Sano M, Nakashima-Kamimura N, Wolf AM, Amo T, Ota S, Katsmnata Y, Fukuda K, Ishiwata K, Suematsu M, Adachi T
- Journal Title
  
  Circulation Research
  
  Volume: 109 Pages: 396-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590814
[Journal Article] Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain.2011
- Author(s)
  Shinmura K, Tamaki K, Sano M, Nakashima-Kamimura N, Alexander MW, Amo T, Ota S, Katsumata Y, Fukuda K, Ishiwata K, Suematsu M, Adachi T.
- Journal Title
  
  Circ Res
  
  Volume: 109(4) Issue: 4 Pages: 396-406
- DOI
  10.1161/circresaha.111.243097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590814, KAKENHI-PROJECT-22790841, KAKENHI-PROJECT-23300257, KAKENHI-PROJECT-23500971, KAKENHI-PROJECT-24651055
[Journal Article] Assessing a shift of glucose biotransformation by LC-MS/MS-based metabolome analysis in carbon monoxide-exposed cells2010
- Author(s)
  Takano N, Yamamoto T, Adachi T, Suematsu M.
- Journal Title
  
  Adv Exp Med Biol. 662
  
  Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Assessing a shift of glucose biotransformation by LC-MS/MS-based metabolome analysis in carbon monoxide-exposed cells.2010
- Author(s)
  N. Takano, T. Yamamoto, T. Adachi, M Suematsu
- Journal Title
  
  Adv Exp Med Biol 662
  
  Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Metabolic Remodeling Induced by Mitochondrial Aldehyde Stress Stimulates Tolerance to Oxidative Stress in the Heart.2009
- Author(s)
  Endo J, Sano M, Adachi T, Suematsu M, Ogawa S, Fukuda K., et. al
- Journal Title
  
  Circ Res 105(11)
  
  Pages: 1118-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart.2009
- Author(s)
  Endo J, Sano M, Katayama T, Hishiki T, Shinmura K, Morizane S, Matsuhashi T, Katsumata Y, Zhang Y, Ito H, Nagahata Y, Marchitti S, Nishimaki K, Wolf AM, Nakanishi H, Hattori F, Vasiliou V, Adachi T, Ohsawa I, Taguchi R, Hirabayashi Y, Ohta S, Suematsu M, Endo J, Sano M, K
- Journal Title
  
  Circ Res 105(11)
  
  Pages: 1118-1127
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Comparative effects of olmesartan and azelnidipine on atrial structural remodeling in spontaneously hypertensive rats.2009
- Author(s)
  Okamura K, Ito M, Tanaka K, Chinushi M, Adachi T, Mitsuma W, Hirono S, Nakazawa M, Kodama M, Aizawa Y
- Journal Title
  
  Pharmacology 83(6)
  
  Pages: 360-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart2009
- Author(s)
  Endo J, Sano M, Katayama T, Hishiki T, Shinmura K, Morizane S, Matsuhashi T, Katsumata Y, Zhang Y, Ito H, Nagahata Y, Marchitti S, Nishimaki K, Wolf AM, Nakanishi H, Hattori F, Vasiliou V, Adachi T, Ohsawa I, Taguchi R, Hirabayashi Y, Ohta S, Suematsu M, Ogawa S, Fukuda K.
- Journal Title
  
  Circ Res 105(11)
  
  Pages: 1118-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Long-term Carperitide Treatment Attenuates Left Ventricular Remodeling in Rats With Heart Failure After Autoimmune Myocarditis.2009
- Author(s)
  Tanaka K, Ito M, Kodama M, Hoyano M, Kimura S, Mitsuma W, Hirono S, Adachi T, Watanabe K, Nakazawa M, Aizawa Y
- Journal Title
  
  J Cardiovasc Pharmacol 54(3)
  
  Pages: 232-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] High plasma levels of matrix metalloproteinase-8 in patients with unstable angina.2009
- Author(s)
  Momiyama Y, Ohmori R, Tanaka N, Kato R, Taniguchi H, Adachi T, Nakamura H, Ohsuzu F
- Journal Title
  
  Atherosclerosis 209(1)
  
  Pages: 206-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Metabolic Remodeling Induced by Mitochondrial Aldehyde Stress Stimulates Tolerance to Oxidative Stress in the Heart2009
- Author(s)
  Endo J, Sano M, Adachi T
- Journal Title
  
  Circulation Research 105
  
  Pages: 1118-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Cosmic effects of rosuvastatin in COSMOS.2009
- Author(s)
  Adachi T, Ohsuzu F
- Journal Title
  
  Circ J 73(11)
  
  Pages: 2015-2016
- NAID
  10025937055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Cosmic effects of rosuvastatin in COSMOS.2009
- Author(s)
  Adachi T, Ohsuzu F
- Journal Title
  
  Circulation Journal 73
  
  Pages: 2015-2016
- NAID
  10025937055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Mercury chloride decreases the water permeability of aquapolin-4-reconstituted Droteoliposomes2008
- Author(s)
  Yukutake, Y., Tsuji, S., Hirano, Y., Adachi, T., Takahashi, T., Fuiihara, K., Agre, P., Yasui, M., Suematsu, M.
- Journal Title
  
  Biol. Cell 100
  
  Pages: 355-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Mercury chloride decreases the water permeability of aquaporine-4-reconstituted proteoliposomes.2008
- Author(s)
  Y. Yukutake, S. Tsuji, Y. Hirano, T. Adachi, et al
- Journal Title
  
  Biol Cell 100
  
  Pages: 355-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Adenosine triphosphate-sensitive potassium channels prevent exte nsion of myocardial ischemia to subepicardium during hemorrhagic Shock.2008
- Author(s)
  M Nakagawa, S. Hori, T. Adachi, et al
- Journal Title
  
  Shock 30
  
  Pages: 178-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Mercury chloride decreases the water permeability of aquaporine-4-reconstituted proteoliposomes.2008
- Author(s)
  Y. Yukutake, S. Tsuji, Y. Hirano, T. Adachi, T. Takahashi, K. Fujihara, P. Agre, M. Yasui, M Suematsu
- Journal Title
  
  Biol Cell 100(6)
  
  Pages: 355-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] High glucose oxidizes SERCA Cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration2008
- Author(s)
  X. Y. Tong, J. Ying, D. Pimentel, M. P. Trucillo, T. Adachi, et al
- Journal Title
  
  J Mol Cell Cardiol 44
  
  Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Adenosine triphosphate-sensitive potassium channels prevent extension of myocardial ischemia to subepicardium during hemorrhagic Shock.2008
- Author(s)
  M Nakagawa, S. Hori, T. Adachi, K. Miyazaki, S. Inoue, M. Suzuki, H. Mori, H. Nakazawa, N. Aikawa, S. Ogawa
- Journal Title
  
  Shock 30(2)(TA is the correspondence author)
  
  Pages: 178-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] High glucose oxidizes SERCA Cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration.2008
- Author(s)
  X.Y. Tong, J. Ying, D. Pimentel, M.P. Trucillo, T. Adachi, R.A. Cohen
- Journal Title
  
  J Mol Cell Cardiol 44(2)
  
  Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] hiol oxidation in signal and response to stress: Detection and quantification of physiological and pathophysiological thiol modifications.2007
- Author(s)
  J. Ying, N. Clavreul, M. Sethuraman, T. Adachi, R.A. Cohen
- Journal Title
  
  Free Radical Biology & Medicine 43(8)
  
  Pages: 1099-1108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Targeting NADPH oxidase: Ets-1 regulates p47phox.2007
- Author(s)
  T. Adachi, M. Yamamoto, M Suematsu
- Journal Title
  
  Circ Res 101
  
  Pages: 962-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Targeting NADPH oxidase: Ets-1 regulates p47phox2007
- Author(s)
  Takeshi Adachi, et. al.
- Journal Title
  
  Circulation Research 101
  
  Pages: 962-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmia via modulation of L-type Ca2+ channels in the heart.2007
- Author(s)
  H. Yada, M. Murata, K. Shimoda, S. Yuasa, H. Kawaguchi, M. Ieda, T. Adachi, M. Murata, S. Ogawa, K. Fukuda
- Journal Title
  
  Circ Res 101(1)
  
  Pages: 69-77
- NAID
  10024457087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390090
[Journal Article] Targeting NAD(P)H oxidase: Ets-1 regulates p47^<phox> expression.2007
- Author(s)
  Adachi, T., Yamamoto, M., Suematsu, M.
- Journal Title
  
  Circ. Res. 101
  
  Pages: 962-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] S-glutathiolation by peroxynitrite of p21Ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.2006
- Author(s)
  Clavreul N, Adachi T, Pimentel DR, et al.
- Journal Title
  
  FASEB Journal (in press)
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Carbon monoxide from heme oxygenase-2 is a tonic regulator against nitric oxide-dependent vasodilatation in the adult rat cerebral microcirculation.2005
- Author(s)
  Ishikawa M, Kajimura M, Adachi T, Maruyama K, Makino N, Goda N, Yamaguchi T, Sekizuka E, Suematsu M
- Journal Title
  
  Circ Res 97(12)
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Carbon monoxide from heme oxygenase-2 is a tonic regulator against nitric oxide-dependent vasodilation in the adult rat cerebral microcirculation2005
- Author(s)
  Ishikawa M, Kajimura M, Adachi T, Maruyama K, Makino N, Suematsu M
- Journal Title
  
  Circulation Research 97(12)
- Data Source
  KAKENHI-PROJECT-17GS0419
[Presentation] Reduced blood flow velocity during flow- mediated dilation measure- ments in diabetic patients: the FMD-J B Study2023
- Author(s)
  Masaki Nobuyuki, Takase Bonpei, Adachi Takeshi
- Organizer
  第87 回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] Effectiveness Of The Ratio Of L-cysteine To L-glutathione In Serum For Prediction Of Cardiovascular Events2023
- Author(s)
  Nobuyuki Masaki, Yuki Ishinoda, Takeshi Adachi
- Organizer
  Arteriosclerosis Thrombosis and Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] Evaluation of Phe- notype and Interaction of Endothelial Function at Different Arterial Levels by Simultaneous Measure- ment of Flow- Mediated Dilation and Endo-PAT; FMD-J B Study2022
- Author(s)
  Masaki Nobuyuki, Takase Bonpei, Adachi Takeshi
- Organizer
  American Heart Association Scientific Sessions 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] Effectiveness of Serum Nitric Oxide Metabolites for Prediction of 10-Year Mortality and Hospital Admission for Heart failure2022
- Author(s)
  Masaki Nobuyuki, Takase Bonpei, Adachi Takeshi
- Organizer
  第86 回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] 血清中一酸化窒素代謝物による死亡リスクの評価2022
- Author(s)
  眞崎　暢之, 人見　泰弘*, 石野田　悠暉*, 高瀬　凡平, 足立　健
- Organizer
  第7 回日本血管不全学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] SERCA2 C674S Modification Leads to Ca2+ Mishandling with Hypertrophy in Right Ventricular Exposed to Hypoxia2021
- Author(s)
  Kazuki Kagami, Kei Ito, Hirotaka Yada, Yusuke Yumita, Midori Iwashita, Yuki Ishinoda, Takayuki Namba, Takumi Toya, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Contributed to the Development of Pulmonary Arterial Hypertension in Mice Through the Impairment of Endothelial Nitric Oxide Synthase Function2021
- Author(s)
  Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Midori Iwashita,Takumi Toya, Yukinori Ikegami, Takayuki Namba, Nobuyuki Masaki, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] 肺高血圧症における右室SERCA2 cys674の関与2021
- Author(s)
  鏡　和樹、弓田　悠介、伊藤　桂、矢田　浩崇、石野田　悠暉、岩下　碧、東谷　卓美、難波　貴之、長友　祐司、足立　健
- Organizer
  日本肺高血圧・肺循環学会
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Loss of Extracellular Signal-Regulated Kinases 2 Using SM22α-Cre Driver Causes Cardiac Failure and Vascular Dysfunction、American Heart Association Scientific sessions,2021
- Author(s)
  Kazuki Kagami, Yusuke Yumita, Midori Iwashita, Yuki Ishinoda, Takayuki Namba, Takumi Toya, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Prognostic Value of Diffusion-Weighted Cardiac Magnetic Resonance Imaging in Hospitalized Heart Failure Patients2021
- Author(s)
  Kazuki Kagami, Takumi Toya, shunpei Kuwaki, Atsushi Sato, Yusuke Yumita, Ayumu Osaki, Midori Iwashita, Risako Yasuda, Yukinori Ikegami, Takayuki Namba, Nobuyuki Masaki, Yuji Nagatomo , Katsumi Hayashi, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] SERCA2 C674S heterozygote knock-in mice revealed Ca2+ mishandling and hypertrophy 　　in right ventricular under hypoxia2021
- Author(s)
  Kazuki Kagami, Kei Ito, Hirotaka Yada, Yusuke Yumita,Yuki Ishinoda, Takayuki Namba, Takumi Toya, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  日本循環器学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] 動脈硬化性疾患のスクリーニング検査としてのCAVI の有効性2021
- Author(s)
  人見　泰弘, 眞崎　暢之, 雪野　碧, 弓田　悠介, 鏡　和樹, 安田　理紗子, 東谷　卓美, 難波　貴之, 長友　祐司, 高瀬　凡平, 足立　健
- Organizer
  第6 回日本血管不全学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] 頸動脈ドップラー超音波検査で算出される拍動指数(Pulsatility Index) は心血管イベントを予測する2021
- Author(s)
  人見　泰弘, 眞崎　暢之, 雪野　碧, 弓田　悠介, 鏡　和樹, 安田　理紗子, 東谷　卓美, 難波　貴之, 長友　祐司, 高瀬　凡平, 足立　健
- Organizer
  第6 回日本血管不全学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08503
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Contributed to the Development of Pulmonary Arterial Hypertension in Mice Through the Impairment of Endothelial Nitric Oxide Synthase Function2021
- Author(s)
  Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Midori Iwashita, Takumi Toya, Yukinori Ikegami, Takayuki Namba, Nobuyuki Masaki, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  日本循環器学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] SM22α-Cre Driven Extracellular Signal-Regulated Kinase 2 Knockout Mice Causes Cardiac Failure and Vascular Dysfunction.2021
- Author(s)
  Kazuki Kagami, Yusuke Yumita, Midori Iwashita, Yuki Ishinoda, Takayuki Namba, Takumi Toya, Risako Yasuda, Yukinori Ikegami, Nobuyuki Masaki, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  The 5th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Characterization of Tolvaptan Responder and Its Impact on the Outcome for Patients with Heart Failure in the Real World2020
- Author(s)
  asuhiro Hitomi, Yuji Nagatomo, Kazuki Kagami, Kei Ito, Atsushi Sato, Risako Yasuda, Takayuki Nanba, Nobuyuki masaki, Hirotaka Yada, Takeshi Adachi
- Organizer
  The 84th annual meeting of the Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Adipose extracellular signal-regulated kinase 2 protected from endothelial dysfunction and the oxidative stress of perivascular adipose tissue in obese mice2020
- Author(s)
  A Osaki , Y Sato , S Endo , K Ito, K Kagami , Y Yumita , Y Ishinoda , T Toya , Y Ido , T Namba , T Adachi
- Organizer
  The 4th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Adipose ERK2 Deficiency in Obese Mice Induced Endothelial Dysfunction by Perivascular Adipose Tissue2020
- Author(s)
  Osaki A, …Adachi T, et al
- Organizer
  第20回NO学会学術集会 YIA
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] 肥満・糖尿病における血管内皮ERK2/TP Receptor経路を介した血管内皮障害2020
- Author(s)
  足立健　佐藤篤志、佐藤泰司、大崎歩、鏡和樹、難波貴之
- Organizer
  2020年　第49回日本心脈管作動性物質　久留米
- Invited
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Contributed to the Development of Pulmonary Arterial Hypertension in Mice2020
- Author(s)
  Yumita Y, …Adachi T,
- Organizer
  The 85th annual meeting of the Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] SERCA2 C674S heterozygote knock-in mice leads to right ventricular failure in hypoxia2020
- Author(s)
  Kagami K, …Adachi T,
- Organizer
  The 85th annual meeting of the Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] 肥満・糖尿病における血管内皮ERK2/TP Receptor経路を介した血管内皮障害2020
- Author(s)
  2）足立健　佐藤篤志、佐藤泰司、大崎歩、鏡和樹、難波貴之
- Organizer
  2020年　第49回日本心脈管作動性物質　久留米
- Invited
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] 心臓カテーテル検査器具から得られた血管内皮細胞のインスリン抵抗性と糖尿病性血管障害との関連2019
- Author(s)
  眞﨑暢之，井戸康夫，高瀬凡平，足立健
- Organizer
  第67回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09565
[Presentation] Endothelial ERK2/Thromboxane Receptor Pathway Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide with High Fat High Sucrose Diet.2019
- Author(s)
  Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Kazuki Kagami Takayuki Namba, Takeshi Adachi;
- Organizer
  European Society of Cardiology 2019 Paris
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Association Between VCAM-1 Expression in Freshly Isolated Arterial Endothelial Cells From Radial Catheter Sheath and Chronic Kidney Disease2019
- Author(s)
  Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, and Takeshi Adachi
- Organizer
  Vascular Discovery 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09565
[Presentation] High Fat High Sucrose Diet Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide Production by ERK2/TP Receptor Pathway.2019
- Author(s)
  Atsushi Sato, Kei Ito, Kazuki Kagami, Ayumu Osaki, Takayuki Namba, Takeshi Adachi
- Organizer
  3rd Japanese Circulation Society BCVR 2019, Tokyo YIA 優秀賞
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] High Fat High Sucrose Diet Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide Production by ERK2/TP Receptor Pathway.2019
- Author(s)
  Atsushi Sato, Kei Ito, Kazuki Kagami, Ayumu Osaki, Takayuki Namba, Takeshi Adachi;
- Organizer
  3rd Japanese Circulation Society BCVR 2019, Tokyo YIA 優秀賞
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Association between arteriosclerosis obliterans and insulin-mediated eNOS activation in freshly isolated arterial endothelial cells from radial catheter sheath2019
- Author(s)
  眞﨑暢之、井戸康夫、高瀬凡平、足立健
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K09565
[Presentation] Association Between VCAM-1 Expression in Freshly Isolated Arterial Endothelial Cells From Radial Catheter Sheath and Chronic Kidney Disease2019
- Author(s)
  Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, and Takeshi Adachi.
- Organizer
  Vascular Disocvery
- Data Source
  KAKENHI-PROJECT-17K09565
[Presentation] Dysfunctional SERCA2 by the Loss of Thiol on Cys674 in Cardiovascular Diseases2019
- Author(s)
  Takeshi Adachi
- Organizer
  83rd Japanese Circulation Society 2019 Plenary Session 12 Frontiers of Basic Cardiovascular Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Association of Hemodynamic Measurements Before Discharge with Lung Congestion.2019
- Author(s)
  Takayuki Namba, Toyokazu Kimura, Risako Yasuda, Takumi Toya, Yuji Nagatomo Nobuyuki Masaki, Hirotaka Yada, Takeshi Adachi
- Organizer
  第22回日本心不全学会 2019年 10月
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] 高脂肪高ショ糖食下における血管内皮ERK2/Thromboxane Receptor Pathwayがスーパーオキサイド産生を介して与える血管内皮機能、インスリン抵抗性および脂肪肝への影響の検討2019
- Author(s)
  佐藤篤志、佐藤泰司、遠藤昌吾、木村豊和、大崎歩、堀井俊平、伊藤桂、鏡和樹、難波貴之　足立健
- Organizer
  2019年第１９回日本NO学会　YIA 優秀賞
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial ERK2/Thromboxane Receptor Pathway Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide with High Fat High Sucrose Diet.2019
- Author(s)
  Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Kazuki Kagami Takayuki Namba, Takeshi Adachi
- Organizer
  European Society of Cardiology 2019 Paris
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Role of Tissue-specific Extracellular Regulatory Kinase 2 in Metabolism and Endothelial Dysfunction of Obese Mice.2019
- Author(s)
  Takeshi Adachi, Yasushi Satoh, Atsushi Sato, Kazuki Kagami
- Organizer
  3rd Japanese Circulation Society BCVR 2019, Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Adipose Extracellular Signal-Regulated Kinase 2 Protect From Ectopic Fat Depositions and Endothelial Dysfunction in Obesity2018
- Author(s)
  Ayumu Osaki, Yasushi Satoh, Shogo Endo, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Toya, Ysauo Ido, Takayuki Namba, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Adipose Extracellular Signal-Regulated Kinase 2 Deficiency Impaired Endothelial Function and the Modulation of Vascular Tone with Adipose Tissue2018
- Author(s)
  Ayumu Osaki, Yasushi Satoh, Shogo Endo, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Toya, Ysauo Ido, Takayuki Namba, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Ectopic Fat Deposition with Organ Damages in Adipose Specific Extracellular Signal-Regulated Kinase 2 Deficient Mice with High Fat Diet2018
- Author(s)
  Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Tohya, Yasuo Ido, Nobuyuki Masaki, Takayuki Namba, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] 血管病におけるNO標的SERCA2の障害2018
- Author(s)
  足立　健
- Organizer
  2018年第71回日本酸化ストレス学会学術集会　第18回日本NO学会合同学術集会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia by catecholamine injection and hypertrophy with Angiotensin II.2018
- Author(s)
  Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] SERCA2 C674S heterozygote kock-in mice with angioteinsion II infusion leads to QT prologation and lethal ventricular arrhythmia due to impaired sarcoplasmic reticulum Ca2+ handling2018
- Author(s)
  Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
- Organizer
  European Society of Cardiology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Pivotal roles of SOD1 in metabolism and vascular dysfunction in mice with obese.2018
- Author(s)
  Takeshi Adachi, Atsushi Sato, Yasunaga Shiraishi, Ayumu Osaki, Toyokazu Kimura, Syunpei Horii, Kei Ito, Takumi Toya, Nobuyuki Masaki, Yasuo Ido
- Organizer
  日本循環器学会総会 (JCS) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Association between Total Cholesterol and Ratio of Direct to Total Bilirubin in Serum2018
- Author(s)
  Masataka Mine, Nobuyuki Masaki, Tetsuya Hisada, Risako Yasuda, Takayuki Namba, Hirotaka Yada, Kenichi Hashimoto, Bonpei Takase, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 induced Hypertension and Endothelial Dysfunction and Insulin Resistance in Obese2018
- Author(s)
  Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takayuki Namba, Takesshi Adachi
- Organizer
  日本循環器学会総会 (JCS) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Angiotensin II loading in SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia2018
- Author(s)
  Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
- Organizer
  日本不整脈学会総会YIA 最優秀賞
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] High Fat/ High Sucrose Diet Did Not Induce Endothelial Dysfunction but Impaired the Reduction of Vascular Tone with Adipose Tissue in Aortic Ring from Mice2018
- Author(s)
  Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Ysauo Ido, Nobuyuki Masaki, Takayuki Namba, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Histological Validation of Cardiac Magnetic Resonance T1 Mapping as an Indicator of Interstitial Myocardial Fibrosis in Non-Ischemic Cardiomyopathy Patients2018
- Author(s)
  Takumi Toya, Nobuyuki Masaki, Katsumi Hayashi, Atsushi Sato, Ayumu Osaki, Kei Ito, Shunpei Horii, Risako Yasuda, Yasuo Ido, Takayuki Namba, Yuji Nagatomo, Hirotaka Yada, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Induced Hypertension and Endothelial Dysfunction and Insulin Resistance in Obese2018
- Author(s)
  Atsushi Sato, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takumi Tohya, Nobuyuki Masaki, Takayuki Namba Takeshi Adachi.
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Adipose Specific Extracellular Signal-Regulated Kinase 2 suppresses Ectopic Fat and limit Organ Damage in Obese2018
- Author(s)
  Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Nobuyuki Masaki ,Takayuki Namba, Takeshi Adachi
- Organizer
  日本循環器学会総会 (JCS) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Increased Basal eNOS Activity in Freshly Isolated Endothelial Cells from Patients with Cardiovascular Disease2018
- Author(s)
  Nobuyuki Masaki, Youhei Yamashita, Toshiyuki Yamada, Yasuo Ido, Risako Yasuda, Takumi Tohya, Takayuki Nanba, Yuji Nagatomo, Hirotaka Yada, Kenichi Hashimoto, Bonpei Takase, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] The mechanism of lean body in SOD1 deficient mice with High Fat High Sucrose Diet: The role of activated AMP-Activated Protein Kinase with Oxidative Stress.2017
- Author(s)
  Atsushi Sato, Yasunaga Shiraishi, Ayumu Osaki, Toyokazu Kimura, Takumi Toya, Risako Yasuda, Takayuki Namba, Hirotaka Yada, Nobuyuki Masaki, Takeshi Adachi
- Organizer
  AHA Scientific Session 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Increases Blood Pressure and Induced Endothelial Dysfunction and Insulin Resistance in Mice with High Fat High Sucrose Diet2017
- Author(s)
  Atsushi Sato, Yasushi Satoh, Endo XXXX, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takayuki Namba, Takeshi Adachi
- Organizer
  AHA Scientific Session 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Deletion of hepatic ERK2 decreased the SERCA2 expressions, which can account for vascular oxidative stress and endothelial dysfunction in metabolic stress2013
- Author(s)
  Adachi T., Nanba T., Satoh Y., Ayaori M., Shiraishi Y., Arai-Nakaya Y., Endo S., Hakuno D., Yada H., Isoda K.,Endo S., Kujiraoka T
- Organizer
  11th International sumposium on mechanisms of vasolidation (MOVD 2013)
- Place of Presentation
  チューリッヒ、スイス
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK2 deficiency develops hepatosteatosis with decreased expression of SERCA2, which can account for metabolic remodeling and endothelial dysfunction2012
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M., Shiraishi Y., Nakaya Y., Endo S., Hakuno D., Isoda K., Adachi T
- Organizer
  米国心臓病学会議2012(AHA 2012)
- Place of Presentation
  ロサンゼルス、米国
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK suppresses endothelial dysfunction with the alleviation of hepatosteatosis and metabolic remodeling in mice fed high-fat and high-sucrose diet2012
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M., Shiraishi Y., Nakaya Y., Endo S., Hakuno D., Isoda K., Adachi T
- Organizer
  欧州心臓学会議2012(ESC2012)
- Place of Presentation
  ミュンヘン、ドイツ
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK protects from endothelial dysfunction with the suppression of hepatic steatosis in mice fed high-fat and high-sucrose diet2011
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M, Hakuno D., Endo S., Niida T., Isoda K., Adachi T
- Organizer
  第84回米国心臓協会学術集会
- Place of Presentation
  オーランド, 米国
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Global COE for humanoid metabolomics system Biology.2008
- Author(s)
  T. Adachi, M Suematsu
- Organizer
  GCOE symposium in UC Davis
- Year and Date
  2008-04-10
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Characterization of the metabolic remodeling in liver by genetic mutation of ALDH2 in muscles.2008
- Author(s)
  T. Hishiki, T. Adachi, M. Sano, T. Takayama, J. Endo, K. Fukuda, M. Suematsu
- Organizer
  FASEB, Experimental Biology
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] CO regulates the glucose metabolism via protein methylation.2008
- Author(s)
  T. Yamamoto, N. Takano, T. Iwabuchi, T. Hishiki, T. Adachi, M. Suematsu
- Organizer
  第33回日本微小循環学会
- Place of Presentation
  東京(邦文)
- Year and Date
  2008-02-21
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Post-translational oxidative modifications in redox-sensitive mechanism2008
- Author(s)
  T. Adachi
- Organizer
  第33回日本微小循環学会
- Place of Presentation
  東京(邦文)
- Year and Date
  2008-02-21
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Mechanism of vasodilatation with N-acethylcysteine and NaHS: Contribution of ATP-sensitive potassium channels.2008
- Author(s)
  M. Yamamoto, T. Adachi, K. Ishiwata, S. Ikeda, Y. Hirayama, T. Soga, M. Suematsu
- Organizer
  FASEB, Experimental Biology
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Vascular Effects of Carbon Monoxide2008
- Author(s)
  T. Adachi, M Kaiimura, T Yamamoto, M Suematsu
- Organizer
  Symposium in 8th Nitric Oxide Society
- Place of Presentation
  仙台
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Vascular proteomics for protein-arginine-methylation in metabolic syndrome.2008
- Author(s)
  T. Adachi, K. Ishiwata, M. Yamamoto, T. Yamamoto, M. Suematsu
- Organizer
  FASEB, Experimental Biology
- Year and Date
  2008-04-07
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Vascular Effects of Carbon Monoxide; Symposium in 8th Nitric Oxide Society of Japan2008
- Author(s)
  T. Adachi, M Kajimura, T Yamamoto, M Suematsu
- Organizer
  Application of metabolome for cardiovascular pathophysiology; CVI seminar, Department of Medicine
- Place of Presentation
  Boston University
- Year and Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Hypomethylation of aortic proteins in metabolic syndrome2008
- Author(s)
  T. Adachi
- Organizer
  GCOE symposium in UC Davis
- Year and Date
  2008-04-10
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Applications of metabolome analysis for cardiovascular diseases.2008
- Author(s)
  T. Adachi
- Organizer
  Global COE, Summer School Lecture
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2008-08-05
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Hypomethylation of aortic proteins in metabolic syndrome.2008
- Author(s)
  T. Adachi
- Organizer
  GCOE symposium
- Place of Presentation
  uc Davis, CA, USA
- Year and Date
  2008-04-10
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Zucker Ratにおける血管内蛋白質メチル化の変化2007
- Author(s)
  足立健、山本美智子、石渡恭子、末松誠
- Organizer
  第25回ヒト細胞学会
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] COによる糖代謝酵素のメチル化修飾と代謝リモデリング2007
- Author(s)
  高野直治、山本雄広、岩渕拓也、足立健、末松誠
- Organizer
  第28回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2007-08-02
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] 一酸化炭素(CO)による細胞内メチル化制御機構の解析第30回日本分子生物学会年会2007
- Author(s)
  山本雄広、高野直治1. 2、菱木貴子、足立健、末松誠
- Organizer
  第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Zucker Ratにおける血管内蛋白質メチル化の変化2007
- Author(s)
  足立健, 他
- Organizer
  第25目日本ヒト細胞学会
- Place of Presentation
  東京都市センターホテル
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Post-translational protein modifications modulated by NO and CO.2007
- Author(s)
  T. Adachi, M. Suematsu
- Organizer
  4th International Redox Meeting
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] N-アセチル-システインおよびNaHSの血管拡張作用とその機序2007
- Author(s)
  山本美智子、足立健、末松誠
- Organizer
  第25回ヒト細胞学会
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] 高温環境におけるラット大動脈のフェニレフリン収縮の検討2007
- Author(s)
  上野浩一、鈴木昌、越智梢、山本美智子、足立健、堀進悟、相川直樹
- Organizer
  臨床体温研究会
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] 血管病における一酸化窒素・一酸化炭素による蛋白質翻訳後修飾2007
- Author(s)
  足立健
- Organizer
  第17回脳血管シンポジウム
- Year and Date
  2007-09-01
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] CO regulates glucose metabolism via protein arginine methylation.2007
- Author(s)
  N. Takano, T. Yamamoto, T. Iwabuchi, T. Adachi, M. Suematsu
- Organizer
  Global COE Satellite Symposium "Metabolic Systems Biology and Liver Disease"
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] Role of stress-inducible CO in regulation of protein methylation and metabolism.2007
- Author(s)
  T. Yamamoto, N. Takano, T. Iwabuchi, T. Adachi, M. Suematsu
- Organizer
  Nobel Forum Symposium for Global COE Program "Gas biology in medicine
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-19390090
[Presentation] 一酸化炭素(CO)による糖代謝酵素のメチル化修飾の解析2007
- Author(s)
  高野直治、山本雄広1、菱木貴子、足立健、末松誠
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390090

1. SATOH Yasushi (10505267)

# of Collaborated Projects: 4 results

# of Collaborated Products: 31 results
2. Masaki Nobuyuki (00364795)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Ido Yasuo (50814133)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
4. SUEMATSU Makoto (00206385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. ENDO Shogo (60192514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 高瀬凡平 (50518214)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
7. 東谷卓美 (60781515)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 菱木貴子 (10338022)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SAITOU Masao (70302239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SOGA Tomoyoshi (60338217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRAO Atsushi (90343350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TANAKA Hirotoshi (00171794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAMOTO Michiko (60445450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
14. IZUMI Yotaroy (90245506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHINMURA Ken (70206332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. FUKUDA Keiichi (20199227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. OTA Shigeo (00125832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. TSUBOTA Kazuo (40163878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SANO Motoaki (30265798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. KAMIMURA Naomi (60283800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YADA Hirotaka (60338051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. HORI Shingo (80129650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MIYAZAKI Koji (90219759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. INOUE Soushin (10193591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Takayuki Namba (90726499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
26. 堤浩二 (00338071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 大澤有紀子 (00816928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 石田治 (20365266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 小林真一 (50724655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. AMIYA Eisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 中島尚美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 真崎暢之

# of Collaborated Projects: 0 results

# of Collaborated Products: 29 results
33. 白石安永

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Adachi Takeshi 足立 健

ADACHI Takeshi 足立 健

ADACHI Ken 足立 健

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Role of ERK2 in Ectopic Fat deposition and Cardiovascular Complications of Type II DiabetesPrincipal Investigator

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Post-translational ,protein modification induced with reactive species in metabolic syndromePrincipal Investigator

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[Book] 細胞学 vol 25(2) 161-1652006

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[Journal Article] A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality2023

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Adachi Takeshi 足立健

ADACHI Takeshi 足立健

ADACHI Ken 足立健