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MYOKAI Fumio  明貝 文夫

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MYOUKAI Fumio  明貝 文夫

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Researcher Number 50263588
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2003 – 2005: Okayama University, University Hospital of Medicine and Dentistry, Assistant Professor, 医学部・歯学部附属病院, 講師
2001 – 2002: Okayama University Graduate School of Medicine and Dentistry, Department of Pathophysiology - Periodontal Science, Instractor, 大学院・医歯学総合研究科, 助手
1998 – 2000: Okayama Univ.Dental Sch., Assistant, 歯学部, 助手
1994: Okayama Univ., Dent.Sch., Assistant Prof., 歯学部, 助手
Review Section/Research Field
Principal Investigator
Periodontal dentistry / Conservative dentistry / Periodontal dentistry
Except Principal Investigator
Periodontal dentistry / Conservative dentistry
Keywords
Principal Investigator
LITAF / 機械的刺激 / Western blot / promoter / 歯周病病態 / 転写制御 / TNF-α / ウエスタンブロット / プロモーター / subtraction … More / mechanical stress / PDL cell / root resorption / 機械的剌激 / サブトラクション / 歯根膜線維芽細胞 / 歯根吸収 / Gene Expression / Cbfal / Bone Regeneration / in situ hybridization / 遺伝子発現 / Cbfa1 / 骨再生 / マイクロアレイ / ヒト歯根膜線維芽細胞 … More
Except Principal Investigator
局所遺伝子導入 / vascular endothelial growth factor / Local Gene Delivery / 組織再生 / Leukotoxin / Phosphorylation / CD11 / CD18 / Cyclic AMP / Protein kinase C / 抗菌ペプチド / 歯周病 / Regulation of inflammation / Antimicrobial peptide / Oral microbe / Utilization of host defense / Local gene therapy / Periodontal Disease / Dentistry / ケミカルトランスフェクション法 / 細胞障害性 / β-ガラクトシダーゼ / ラット唾液腺 / 局所的遺伝子療法 / 唾液 / 顎下腺 / ヒトβ-defensin-2 / 遺伝子治療 / 炎症制御 / 口腔細菌 / 生体機能利用 / 局所遺伝子治療 / 歯学 / leukocyte / bacterial detection / periodontal desease / oral infection control / compromised host / PBSCT / 白血球数 / 細菌検査 / 歯周疾患 / 口腔管理 / 易感染性宿主 / 末梢血幹細胞移植 / single nucleotide polymorphism / drug metabolizing enzyme / anti-angiogenic effect / deficient mice / cathepsin-L / lysosomal enzymes / drug-induced gingival overgrowth / I-cell病 / サイクロスポリン / ニフェジピン / 表現型 / 欠損マウス / カテプシン / 免疫抑制剤 / 抗てんかん薬 / Ca拮抗剤 / Dose(D)ratio / Concentration(C) / CYP2C19 / CYP2C9 / チトクロームP450 / フェニトイン / 薬物代謝 / 遺伝子多型 / 薬物代謝酵素 / 血管新生抑制作用 / 遺伝子欠損マウス / カテプシン-L / ライソゾーム酵素 / 薬物性歯肉増殖症 / Anti-inflammatory Therapy / Regulation of Gene Transcription / TNF / Periodontal disease / 抗炎症療法 / 遺伝子転写制御 / 腫瘍壊死因子 / 歯周炎 / Tissue regeneration / Gene transcription / Reparative dentin / Dental pulp / 遺伝子サブトラクション / 遺伝子発現 / 修復象牙質 / 歯髄 / Regulation of cell function / Periodontal tissue regeneration / TGF-beta receptor / Transforming growth factor-beta (TGF-beta) / Periodontal ligament fibroblast / 活性型ビタミンD_3レセプター / アルカリホスフォターゼ活性 / コラーゲン合成 / DNA合成 / トランスフォーミング成長因子(TGF-β) / in situハイブリダイゼーション / 機械的外力 / セリンスレオニンキナーゼレセプター発現 / TGF-β / 細胞機能制御 / 歯周組織再生 / トランスフォーミング成長因子(TGF-β)レセプター / トランスフォーミング成長因子 / 歯根膜線維芽細胞 / A.actinomycetemcomitans / Intracellular calucium ion / cAMP / FMLP / LFA-1 / プロテインキナーゼC / 走化能 / 好中球 / 若年性歯周炎 / Actinobacillus actinomycetemcomitans / Intercellular calcium ion / 局所炎症と全身 / 可溶性TNF-α受容体 / 炎症性サイトカイン / マウスモデル / Porphyromonas gingivalis / 誤嚥性肺炎 / IL-6 / IL-1β / sTNFR2 / sTNFR1 / TNF-α / 唾液(腺) / 上皮(細胞) / 細菌感染制御 Less
  • Research Projects

    (13 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (23 People)
  •  歯周靭帯細胞における機械的ストレス応答性遺伝子のグルーピングと転写機構Principal Investigator

    • Principal Investigator
      明貝 文夫
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  歯周病原性細菌によって起こる誤嚥性肺炎の分子免疫学的病態の研究

    • Principal Investigator
      高柴 正悟
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Gene Therapy for Periodontal Diseases -Regulation of host response by local gene delivery-

    • Principal Investigator
      TAKASHIBA Shogo
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Role of a novel transcription factor for TNF-α, LITAF, on the pathogenesis of periodontitisPrincipal Investigator

    • Principal Investigator
      MYOKAI Fumio
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Study on the pathogenesis of drug-induced gingival overgrowth -A study with deficient mice

    • Principal Investigator
      NISHIMURA Fusanori
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Study for oral infectious control during peripheral blood stem cell transplantation

    • Principal Investigator
      TANIMOTO Ichiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Periodontal Treatment by Regulation of Novel TNF-α Transcription Factor in Monocytes

    • Principal Investigator
      TAKASHIBA Shogo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Factor for induction of root resorptionPrincipal Investigator

    • Principal Investigator
      MYOKAI Fumio
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      OKAYAMA UNIVERSITY
  •  上皮由来抗菌ペプチドの利用による歯周病原性細菌の感染予防にむけて

    • Principal Investigator
      TAKASHIBA Shogo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Study for preservation of dentin using local gene deliveryof dentin-specific genes

    • Principal Investigator
      TAKASHIBA Shogo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Studies on bone regeneration by application of osteoblast differentiation marker, Cbfal, gene productsPrincipal Investigator

    • Principal Investigator
      MYOKAI Fumio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Study on the control of periodontal ligament fibroblast functions by transforming growth factor

    • Principal Investigator
      ARAI Hideo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Okayama University
  •  Studies on signal transduction of neutrophils from early-onset periodonititis patients

    • Principal Investigator
      KURIHARA Hidemi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Okayama University

All 2005 2004

All Journal Article

  • [Journal Article] Mechanical Stress-induced Gene Expression Essential for HPLF Growth2005

    • Author(s)
      YAMASHIRO, K., MYOKAI, F., HIRATSUKA, K., SENOO, K., NISHIMURA, F., ABIKO, Y., TAKASHIBA, S.
    • Journal Title

      Journal of Dental Research Abstract(In press)

    • Data Source
      KAKENHI-PROJECT-16659579
  • [Journal Article] 機械的刺激が培養ヒト歯根膜線維芽細胞に及ぼす遺伝子発現変化のマイクロアレイ解析2004

    • Author(s)
      山城圭介, 平塚浩一, 明貝文夫, 妹尾京子, 高柴正悟, 安孫子宜光
    • Journal Title

      日本歯周病学会会誌 46(春季特別号)

      Pages: 124-124

    • NAID

      10012896011

    • Data Source
      KAKENHI-PROJECT-16659579
  • 1.  TAKASHIBA Shogo (50226768)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 2 results
  • 2.  NISHIMURA Fusanori (80208222)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 1 results
  • 3.  MAEDA Hiroshi (00274001)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  ARAI Hideo (70222718)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  MURAYAMA Yoji (50029972)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  KOHNO Takayuki (80284074)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  苔口 進 (10144776)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  大山 秀樹 (90280685)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KURIHARA Hidemi (40161765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  HONGYO Hiroshi (80243476)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NAKAGAWA Masatsugu (80243468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  ISOSHIMA Osamu (90176256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  WASHIO Norifumi (40263602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAKAHASHI Keiso (70243475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TANIMOTO Ichiro (00280686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MINESHIBA Fumi (90346461)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NARUISHI Koji (00346446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KUBOKI Takuo (00225195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KUBOTA Satoshi (90221936)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  宮本 学 (40252978)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  小林 芳友 (90234856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  永井 淳 (70252989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  滝川 雅之 (60243474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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