YAMASHITA Yoshiki 山下能毅

Researcher Number	50268207
Affiliation (based on the past Project Information) *help	2015: 大阪医科大学, 医学部, その他 2015: 大阪医科大学, 医学部, 講師 2013 – 2015: 大阪医科大学, 医学部, 非常勤講師 2007 – 2013: 大阪医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 生殖医学 / ミトコンドリア / 不妊症 / 顆粒膜細胞 / 抗ミュラー管ホルモン(AMH) / AMHレセプタ / 一塩基多型(SNP) / mtDNA4677 / real time PCR / 妊馬血ゴナドトロピン … More / ラットの顆粒膜細胞 / IVF-ET / hMG / recFSH / ＡＭＨ / AMH: 146 T>G / -482 A>G / IVS1+149 T>A / IVS5-6 C>T / ＡＭＨＲ / 抗ミュウラー管ホルモン / 子宮内膜症 / 不妊 / 体外受精 / 一塩基多型 / ＳＮＰ / AMH　１４６T>G / AMHRII+１４９　T>A / ISV10+77　A>G / ISV５−６　C>T / Genotyping assay … More Except Principal Investigator 卵巣癌 / EMT / CD24 / マイクロアレイ / 薬剤反応性 / シグナル伝達 / トランスレーショナルリサーチ / 癌 / シスプラチン / タキソール / アポトーシス / プロモーターマイクロアレイ / NFkB / SiRNA / IAPファミリー / アデノウイルス / 子宮内膜癌 / HGF / Met / ABC transporter / ﾐｾﾙ / Foretinib / ミセル / 上皮間葉形態転換 / 婦人科悪性腫瘍 / 抗がん剤 / 血管内皮障害 / フィブラート / 一酸化窒素 / TC療法 / 動脈硬化 / 血管内皮機能 / 抗癌剤 / ドラッグデリバリー / 腹膜播種転移 / 薬剤耐性 / 高分子ミセル / 卵巣がん / drug delivery system / E-cadherin / Snail / colony formation Less

Analyzing the possible involvement of anti-Müllerian hormon and anti-Müllerian hormon receptor II single nucleotide polymorphism in infertilityPrincipal Investigator
- Principal Investigator
  
  Yamashita Yoshiki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
CD24-targeting drug delivery system enhanced effect of cisplatin-resistant ovarian cancer cells
- Principal Investigator
  
  TERAI YOSHITO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
To control in invasion and metastasis through EMT (Epithelial-Mesenchymal-Transition) functional analysis of CD24 in endometrial cancer
- Principal Investigator
  
  OHMICHI Masahide
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
Fibrates protect against vascular endothelial dysfunction induced by paclitaxel and carboplatin chemotherapy for cancer patients: a pilot study.
- Principal Investigator
  
  TANABE Akiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
Analyzing how defects of Mitochondria DNA affect oocyte maturation.Principal Investigator
- Principal Investigator
  
  YAMASHITA Yoshiki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
Analysis of chemo-resistance genes with promoter micro-array in ovarian cancer
- Principal Investigator
  
  OHMICHI Masahide
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College

All 2015 2014 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Analysis of the methylation rate of the androgen receptor promoter region in granulosa cells in moderate to severe endometriosis patients undergoing controlled ovarian hyperstimulation2015
- Author(s)
  Yoko Nakamura, M.D., Yoshiki Yamashita, M.D., Natsuho Saito, M.D., Hikaru Yamamoto M.D., Masami Hayashi, M.D. Yoshito Terai, M.D., Masahide Ohmichi, M.D.
- Journal Title
  
  Journal of Reproductive Endocrinology & Infertility
  
  Volume: 1 Pages: 1-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462581
[Journal Article] Analyzing the possible involvement of anti-Müllerian hormone and anti-Müllerian hormone receptor II single nucleotide polymorphism in infertility.2014
- Author(s)
  Yoko Yoshida, Yoshiki Yamashita, Atushi Hayashi,
- Journal Title
  
  Journal of assisted reproduction and genetics
  
  Volume: 2 Pages: 163-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462581
[Journal Article] Decorin induced by progesterone plays a crucial role in suppressing endometriosis.2014
- Author(s)
  Ono YJ, Terai Y, Tanabe A, Hayashi A, Hayashi M, Yamashita Y, Kyo S, Ohmichi
- Journal Title
  
  J Endocrinol
  
  Volume: 223 Pages: 203-216
- DOI
  10.1530/joe-14-0393
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390384
[Journal Article] MTX could be First-Line Therapy Even in Cases where hCG Level is Greater than 5,000 IU/ml2012
- Author(s)
  Yoshiki Yamashita, Sousuke Katoh, Yoko Yoshida, Satoe Fujiwara, Sachiko Kawabe, Mika Hayashi, Atsushi Hayashi, Yoshito Terai, Masahide Ohmichi
- Journal Title
  
  Ectopic pregnancy Modern Diagnosis and Management
  
  Pages: 209-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Impact of platinum-based chemotherapy on the progression of atherosclerosis2011
- Author(s)
  Sekijima T, Tanabe A, . Maruoka R, Fujishiro N, Fujiwara S, Yuguchi Y, Yamashita Y, Terai Y and Ohmichi M.
- Journal Title
  
  Climacteric
  
  Volume: 14 Pages: 31-40
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Prognostic effect of epidermal growth factor receptor gene mutations and the aberrant phosphorylation of Akt and ERK in ovarian cancer2011
- Author(s)
  Yoshimichi Tanaka, Yoshito Terai, Akiko Tanabe, Hiroshi Sasaki, Tatsuharu Sekijima, Satoe Fujiwara, Yoshiki Yamashita, Masanori Kanemura, Masatsugu Ueda, Michio Sugita, Wilbur A. Franklin and Masahide Ohmichi
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 11 Pages: 50-57
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] MTX could be First-Line Therapy Even in Cases where hCG Level is Greater than 5,000 IU/ml2011
- Author(s)
  Yoshiki Yamashita, Sousuke Katoh, Yoko Yoshida, Satoe Fujiwara, Sachiko Kawabe, Mika Hayashi, Atsushi Hayashi, Yoshito Terai and Masahide Ohmichi
- Journal Title
  
  Ectopic Pregnancy-Modern Diagnosis and Management.
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Does advanced-stage endometriosis affect the gene expression of estrogen and progesterone receptors in granulose cells?2011
- Author(s)
  Karita M, Yamashita Y, Hayashi A, Yoshida Y, Hayashi M, Yamamoto H, Tanabe A, Terai Y, Ohmichi M
- Journal Title
  
  Fertility and Sterility
  
  Volume: 95 Pages: 889-894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Does advanced-stage endometriosis affect the gene expression of estrogen and progesterone receptors in granulose cells?2011
- Author(s)
  Karita M, Yamashita Y, Hayashi A, Yoshida Y, Hayashi M, Yamamoto H, Tanabe A, Terai Y and Ohmichi M.
- Journal Title
  
  Fertil Steril
  
  Volume: 95 Pages: 889-894
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] A Case of Concomitant Pregnancy Following Supplement of Mestranol and Norethisterone to Control the Menstrual Cycle2010
- Author(s)
  Tomohito Tanaka, Yoshiki Yamashita, Sousuke Kato, Takashi Kato, Yoshito Terai and Masahide Ohmichi
- Journal Title
  
  Bull OMC
  
  Volume: 56 Pages: 91-94
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Topotecan as a molecular targeting agent which blocks the Akt and VEGF cascade in platinum-resistant ovarian cancers2010
- Author(s)
  Tsunetoh S, Terai Y, Sasaki H, Tanabe A, Tanaka Y, Sekijima T, Fujioka S, Kawaguchi H, Kanemura M, Yamashita Y, Ohmichi M
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 10 Pages: 1137-114
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Remarkable Lethal G-to-A Mutations in vif-Proficient HIV-1 Provirus by Individual APOBEC3 Proteins in Humanized Mice2010
- Author(s)
  Kei Sato, Taisuke Izumi, Naoko Misawa, Tomoko Kobayashi, Yoshiki Yamashita, Masahide Ohmichi, Mamoru Ito, Akifumi Takaori-Kondo, and Yshio Koyanagi
- Journal Title
  
  J Virol
  
  Volume: 4 Pages: 9546-9556
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Mature cystic teratoma of the fallopian tube2010
- Author(s)
  Satoe Fujiwara, Yoshiki Yamashita, Yoko Yoshida, Yoshito Terai, Kiyoji Okuda, Masahide Ohmichi
- Journal Title
  
  Fertil Steril
  
  Volume: 92 Pages: 2708-2709
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Long-term follow-up of neoadjuvant intraarterial chemotherapy using an original four-lumen double-balloon(4L-DB) catheter for locally advanced uterine cervical cancer2009
- Author(s)
  Terai Y, Kanemura M, Sasaki H, Tsunetoh S, Tanaka Y, Yamashita Y, Yamamoto K, Sasaki H, Yamashita Y, Kanemura, Ohmichi M.
- Journal Title
  
  M, Int J Clin Oncol
  
  Volume: 14 Pages: 56-62
- NAID
  10025147392
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Effectiveness of laparoscopic surgery against antibiotics-resistant pelvic inflammatory disease2009
- Author(s)
  Yamashita Y., Okuda K., Hayashi A., Terai Y., Ohmichi M.
- Journal Title
  
  Bull of OMC
  
  Volume: 15 Pages: 1-7
- NAID
  130001223243
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] A case of an MTX-resistant ectopic pregnancy where Dactinomycin was effective as a second-linechemotherapy2009
- Author(s)
  Fujioka S., Yamashita Y., Asano M., Hayashi A., Ohmichi M
- Journal Title
  
  Fertil Steril
  
  Volume: 91
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] A case of a methotrexate-resistant ectopic pregnancy in which dactinomycin was effective as a second-line chemotherapy2009
- Author(s)
  Fujioka S, Yamashita Y, Kawabe S, Kamegai H, Terai Y, Ohmichi M
- Journal Title
  
  Fertil Steril
  
  Volume: 91
- Data Source
  KAKENHI-PROJECT-21592117
[Journal Article] Successful pregnancy after conservative surgery for stage IA endometrial cancer in a young woman2009
- Author(s)
  Yasuda M, Terai Y, Sekijima T, Sasaki H, Yamashita Y, Kanemura M, Ohmichi M
- Journal Title
  
  Fertil Steril
  
  Volume: 91
- Data Source
  KAKENHI-PROJECT-21592117
[Presentation] 体外受精治療下黄体化顆粒膜細胞におけるBMP15,GDF9 mRNAの発現の臨床的検討2012
- Author(s)
  川辺紗智子、吉田陽子、山下能毅、林篤史、林美佳、林正美、大道正英
- Organizer
  日本産婦人科学会
- Place of Presentation
  神戸
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-21592117
[Presentation] 子宮内膜症症例の顆粒膜細胞におけるアンドロゲンレセプター(AR)の発現とメチル化の有無の検討2011
- Author(s)
  林美佳、川辺紗智子、吉田陽子、山下能毅、林篤史、林美佳、林正美、大道正英
- Organizer
  生殖医学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-08
- Data Source
  KAKENHI-PROJECT-21592117

1. OHMICHI Masahide (10283764)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
2. TERAI Yoshito (90278531)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
3. TANABE Akiko (70454543)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
4. HAYASHI Masami (00551748)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
5. KANEMURA Masanori (40298782)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. TANAKA Yoshimichi (10625502)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SAKATA Masahiro (10260639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HAYASHI Atushi (80411338)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. TSUNETOH Satoshi (70388255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SASAKI Hiroshi (80432491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAMEGAI Hideki (30204639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TASAKA Keiichi (50155058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAHARA Masahiro (00294091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAYAKAWA Jun (80397736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HASHOMOTO Namiko (60379253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAKEHARA Mikio (40298766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Yoo Saha (80625674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKAMURA Kiyoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMASHITA Yoshiki 山下 能毅

Research Projects

Research Products

Co-Researchers

Analyzing the possible involvement of anti-M&uuml;llerian hormon and anti-M&uuml;llerian hormon receptor II single nucleotide polymorphism in infertilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CD24-targeting drug delivery system enhanced effect of cisplatin-resistant ovarian cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To control in invasion and metastasis through EMT (Epithelial-Mesenchymal-Transition) functional analysis of CD24 in endometrial cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fibrates protect against vascular endothelial dysfunction induced by paclitaxel and carboplatin chemotherapy for cancer patients: a pilot study.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyzing how defects of Mitochondria DNA affect oocyte maturation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of chemo-resistance genes with promoter micro-array in ovarian cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of the methylation rate of the androgen receptor promoter region in granulosa cells in moderate to severe endometriosis patients undergoing controlled ovarian hyperstimulation2015

Author(s)

Journal Title

Data Source

[Journal Article] Analyzing the possible involvement of anti-Müllerian hormone and anti-Müllerian hormone receptor II single nucleotide polymorphism in infertility.2014

Author(s)

Journal Title

Data Source

[Journal Article] Decorin induced by progesterone plays a crucial role in suppressing endometriosis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MTX could be First-Line Therapy Even in Cases where hCG Level is Greater than 5,000 IU/ml2012

Author(s)

Journal Title

Data Source

[Journal Article] Impact of platinum-based chemotherapy on the progression of atherosclerosis2011

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic effect of epidermal growth factor receptor gene mutations and the aberrant phosphorylation of Akt and ERK in ovarian cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] MTX could be First-Line Therapy Even in Cases where hCG Level is Greater than 5,000 IU/ml2011

Author(s)

Journal Title

Data Source

[Journal Article] Does advanced-stage endometriosis affect the gene expression of estrogen and progesterone receptors in granulose cells?2011

Author(s)

Journal Title

Data Source

[Journal Article] Does advanced-stage endometriosis affect the gene expression of estrogen and progesterone receptors in granulose cells?2011

Author(s)

Journal Title

Data Source

[Journal Article] A Case of Concomitant Pregnancy Following Supplement of Mestranol and Norethisterone to Control the Menstrual Cycle2010

Author(s)

Journal Title

YAMASHITA Yoshiki 山下能毅

Analyzing the possible involvement of anti-Müllerian hormon and anti-Müllerian hormon receptor II single nucleotide polymorphism in infertilityPrincipal Investigator