Kosaka Mitsuko 小阪美津子

… Alternative Names

KOSAKA MITSUKO 小阪美津子

KOSAKA Mitsuko 小阪美津子

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Researcher Number	50270476
Other IDs	https://orcid.org/0000-0001-6146-5184
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 岡山大学, 医歯薬学域, 助教 2019 – 2020: 岡山大学, 医歯薬学総合研究科, 助教 2016: 岡山大学, 医歯薬学総合研究科, 助教 2015: 岡山大学, 医歯(薬)学総合研究科, 助教 2011 – 2013: 岡山大学, 医歯(薬)学総合研究科, 助教 … More 2008: Okayama University, 医学部, 客員研究員 2007: The Institute of Physical and Chemical Research, 体性組織幹細胞研究ユニット, ユニットリーダー 1995 – 1996: 岡崎国立共同研究機構, 基礎生物学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 55040:Respiratory surgery-related / General anatomy (including histology/embryology) / Developmental biology Except Principal Investigator Developmental biology / Basic Section 56070:Plastic and reconstructive surgery-related
Keywords	Principal Investigator 幹細胞 / がん / 転写調節因子 / 再生 / 発生 / 網膜 / ライブイメージング / 遺伝子発現制御 / 悪性度 / がん進展 … More / SPP1 / 発現制御機構 / 浸潤 / 細胞移動 / 癌の悪性進展 / 発現調節機構 / 早期診断法 / 転移 / 予後予測 / 悪性進展 / 癌 / 体細胞 / 可塑性 / 体性組織幹細胞 / 多分化能 / 体性組織 / 組織幹細胞 / 国際情報交換 / Oct3/4 / cone / 視細胞 / 網膜変性疾患 / 細胞分化 / レンズ再生 / 再分化 / 脱分化 / 色素上皮細胞 / 分化転換 … More Except Principal Investigator Transdifferentiation / FGF / 分化転換 / 再生 / Axillary reverse mapping / 支持療法 / 乳癌術後 / 腋窩リンパ節 / axillary reverse mapping / センチネルリンパ節 / 乳癌 / リンパ浮腫 / Gene expression / Homebox gene / Growth factor / Pigmented epithelial call / Stabilization in differentiation / Dedifferentiation / 脊椎動物 / 分化制御因子 / 増殖因子 / 細胞外基質 / 遺伝子発現調節 / ホメオボックス遺伝子 / 成長因子 / 色素上皮細胞 / 分化の安定化 / 脱分化 / Aging / Newt / Lens / Gene Expression / Regeneration / Development / レンズ / 色素上皮 / 遺伝発現 / 網膜 / アフリカツメガエル / 加齢 / イモリ / 水晶体 / 遺伝子発現 / 発生 Less

上肢リンパ地図がもたらす乳がん術後リンパ浮腫予防
- Principal Investigator
  
  木股敬裕
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Okayama University
Elucidation and application of the regulatory mechanism of SPP1 gene in human cancer cellsPrincipal Investigator
- Principal Investigator
  
  KOSAKA MITSUKO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Cellular plasticity of OCT4 expressing somatic cellsPrincipal Investigator
- Principal Investigator
  
  KOSAKA MITSUKO
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Okayama University
Role of Oct3/4 in retinal development and dieseasesPrincipal Investigator
- Principal Investigator
  
  KOSAKA MITSUKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
Key genes related to retinal development and diseasesPrincipal Investigator
- Principal Investigator
  
  KOSAKA Mitsuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
  The Institute of Physical and Chemical Research
虹彩色素上皮細胞によるレンズ細胞への分化転換機構Principal Investigator
- Principal Investigator
  
  小阪美津子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Developmental biology
- Research Institution
  Okazaki National Research Institutes
Molecular Mechanism of Transdifferentiation in Regeneration
- Principal Investigator
  
  KODAMA Ryuji, EGUCHI Goro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Developmental biology
- Research Institution
  Okazaki National Research Institutes
Molecular Mechanisms of Transdifferentiation and Stabilization in Differentiation of Animal Tissue Cells
- Principal Investigator
  
  EGUCHI Goro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute for Basic Biology (NIBB), Okazaki National Research Institutes

All 2022 2021 2020 2017 2016 2015 2014 2013 2011 2008 2007

All Journal Article Presentation Patent

[Journal Article] Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma2020
- Author(s)
  Koshimune Seijiro、Kosaka Mitsuko、Mizuno Nobuhiko、Yamamoto Hiromasa、Miyamoto Tomoyuki、Ebisui Kohta、Toyooka Shinichi、Ohtsuka Aiji
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1
- DOI
  10.1186/s12885-020-06969-0
- NAID
  120006869585
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09287
[Journal Article] Immediate differentiation of neuronal cells from stem/progenitor-like cells in the avian iris tissues2014
- Author(s)
  T. Matsushita, A. Fujihara, L. Royall, S. Kagiwada, M. Kosaka and M. Araki
- Journal Title
  
  Exp Eye Res
  
  Volume: 123 Pages: 16-26
- DOI
  10.1016/j.exer.2014.04.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22124001, KAKENHI-PROJECT-23592606
[Journal Article] Architecture of the Subendothelial Elastic Fibers of Small Blood Vessels and Variations in Vascular Type and Size2013
- Author(s)
  Akira Shinaoka
- Journal Title
  
  Microscopy and Microanalysis
  
  Volume: 19 Issue: 2 Pages: 406-414
- DOI
  10.1017/s1431927612014341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591542, KAKENHI-PROJECT-23390348, KAKENHI-PROJECT-23592606, KAKENHI-PROJECT-24700531
[Journal Article] Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled42011
- Author(s)
  Ohta K, Ito A, Kuriyama S, Lupo G, Kosaka M, Ohnuma S, Nakagawa S, Tanaka H
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108(36) Issue: 36 Pages: 14962-7
- DOI
  10.1073/pnas.1100513108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592606
[Journal Article] /Iris pigment epithelium as a potential source for both basic biology and therapeutic applications for retinal regeneration/2008
- Author(s)
  Mitsuko Kosaka
- Journal Title
  
  Strategies for Retinal Tissue Repair and Regeneration in Vertebrates:From Fish to Human
  
  Pages: 139-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592048
[Journal Article] Novel variants of Oct-3/4 gene expressed in mouse somatic cells2008
- Author(s)
  Mizuno, N and Kosaka, M.
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 30997-31004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592048
[Journal Article] Iris pigment epithelium as a potential source for both basic biology and therapeutic applications for retinal regeneration2008
- Author(s)
  Mitsuko, Kosaka
- Journal Title
  
  Strategies for retinal tissue repair and regeneration in vertebnrates : From fish to human
  
  Pages: 139-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592048
[Journal Article] Novel variants of Oct-3/4 gene expressed in mouse somatic cells.2008
- Author(s)
  Mizuno N, Kosaka M
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 30997-31004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592048
[Journal Article] Multipotent cells from mammalian iris pigment epithelium2007
- Author(s)
  Asami, M, Sun, GW, Yamaguchi, M, Kosaka, M.
- Journal Title
  
  Developmental Biology 304
  
  Pages: 433-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592048
[Journal Article] Multipotent cells from mammalian iris pigment epithelium2007
- Author(s)
  Asami Sun Yamaguchi Kosaka
- Journal Title
  
  Developmental Biology 304
  
  Pages: 433-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592048
[Patent] 癌検出キット、および、癌診断のためのデータの取得方法2016
- Inventor(s)
  小阪美津子、水野伸彦
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-073956
- Filing Date
  2016-03-31
- Data Source
  KAKENHI-PROJECT-15K15016
[Presentation] Biological and clinical value of OCT4A/SPP1C axis in endometrial and lung adenocarcinoma2022
- Author(s)
  入江恭平、水野伸彦、宮本朋幸、大塚愛二、山本寛斎、豊岡伸一、増山寿、小阪美津子
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09287
[Presentation] 早期癌の予後不良を左右する分子軸の診断・治療への応用2021
- Author(s)
  入江恭平、水野伸彦、小阪美津子
- Organizer
  岡山県リサーリパーク　研究シーズ発表会2021
- Data Source
  KAKENHI-PROJECT-19K09287
[Presentation] 子宮内膜癌および肺腺癌細胞におけるOCT4A/SPP1C共発現とその臨床的意義2021
- Author(s)
  入江恭平、水野伸彦、越宗靖二郎、宮本朋幸、大塚愛二、山本寛斎、豊岡伸一、増山寿、小阪美津子
- Organizer
  第３０回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09287
[Presentation] マウスとヒトにおけるPOU5F1遺伝子産物2020
- Author(s)
  小阪美津子
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-19K09287
[Presentation] 虹彩および網膜に存在する組織幹細胞の実態2017
- Author(s)
  小阪美津子, 大塚愛二
- Organizer
  第122回日本解剖学会総会・学術集会シンポジウム講演
- Place of Presentation
  長崎大学
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K15016
[Presentation] ヒトPOU5F1 遺伝子ヴァリアントがコードするOCT4Cタンパク質の特性2017
- Author(s)
  上園深希, 戎井孝太, 水野伸彦, 小阪美津子, 大塚愛二
- Organizer
  第122回日本解剖学会総会・学術集会一般演題
- Place of Presentation
  長崎大学
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K15016
[Presentation] ヒトOct4遺伝子とOct4偽遺伝子の機能的差異2015
- Author(s)
  戎井孝太、大前凌、水野伸彦、小阪美津子、大塚愛二
- Organizer
  日本解剖学会第７０回中国・四国支部学術集会
- Place of Presentation
  愛媛大学
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K15016
[Presentation] ヒト癌細胞で発現するOct3/4遺伝子variantの同定2013
- Author(s)
  宮本朋幸、水野伸彦、大野英治、大塚愛二、小阪美津子
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  サンポート高松、香川
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23592606
[Presentation] 体性組織で発現するOct3/4遺伝子variantの機能解析2013
- Author(s)
  三宅望、高畠あゆむ、水野伸彦、小阪美津子、大塚愛二
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  サンポート高松、香川
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23592606
[Presentation] マウスOct3/4遺伝子variantがコードするOct3/4C蛋白質の性状解析2013
- Author(s)
  入江恭平、水野伸彦、小阪美津子、大塚愛二
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  サンポート高松、香川
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23592606
[Presentation] マウスOct3/4遺伝子variantがコードするOCT3/4Cタンパク質の性状解析2013
- Author(s)
  入江恭平、水野伸彦、小阪美津子、大塚愛二
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  サンポート高松、香川
- Data Source
  KAKENHI-PROJECT-23592606
[Presentation] ヒトOct4遺伝子発現解析における問題点の克服2013
- Author(s)
  宮本朋幸、小阪美津子、水野伸彦、大野英治、大塚愛二
- Organizer
  第６８回日本解剖学会中四国支部学術集会
- Place of Presentation
  鳥取大学医学部米子キャンパス
- Data Source
  KAKENHI-PROJECT-23592606
[Presentation] ヒトOct4遺伝子発現解析における問題点の克服2013
- Author(s)
  宮本朋幸、小阪美津子、水野伸彦、大野英治、大塚愛二
- Organizer
  鳥取大学医学部
- Place of Presentation
  鳥取
- Year and Date
  2013-10-19
- Data Source
  KAKENHI-PROJECT-23592606
[Presentation] 組織幹細胞の実体解明から癌幹細胞研究への新展開2008
- Author(s)
  小阪美津子
- Organizer
  第2回産学官連携新産業創出研究会「大腸癌幹細胞の生物学的特性の解析と新癌治療法の開発」研究会
- Place of Presentation
  岡山
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-19592048
[Presentation] 体細胞のフレキシビリティの理解と応用2008
- Author(s)
  小阪美津子
- Organizer
  第35回日本臓器保存生物医学定期学術集会シンポジウム講演
- Place of Presentation
  東京
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-19592048
[Presentation] 体細胞のフレキシビリティの理解と応用2008
- Author(s)
  小阪美津子
- Organizer
  第35回日本臓器保存生物医学定期学術集会 (シンポジウム講演
- Place of Presentation
  東京都六本木ヒルズ
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-19592048
[Presentation] 眼組織幹細胞としての虹彩上皮細胞の基礎と応用2007
- Author(s)
  小阪美津子
- Organizer
  第34回日本臓器保存生物医学定期学術集会シンポジウム講演
- Place of Presentation
  北海道
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19592048
[Presentation] Developmental plasticity of cone-photoreceptor precursor cells in postnatal mouse retina2007
- Author(s)
  Watanabe, Asami, Sun, Tsuchida, Kosaka
- Organizer
  第40回日本発生生物・細胞生物学会合同大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-05-28
- Data Source
  KAKENHI-PROJECT-19592048
[Presentation] Developmental plasticity of cone-photoreceptor precursor cells in postnatal mouse retina2007
- Author(s)
  渡邉康行、浅見真紀、孫こうい、土田順二、小阪美津子
- Organizer
  第40回日本発生生物・細胞生物学会合同大会
- Place of Presentation
  福岡
- Year and Date
  2007-05-28
- Data Source
  KAKENHI-PROJECT-19592048

1. EGUCHI Goro (80022581)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. MIZUNO Nobuhiko (60462735)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. KODAMA Ryuji (90161950)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MOCHII Makoto (90202358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TSONIS Panagiotis

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OHTUKA Aiji (50168986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 木股敬裕 (50392345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 品岡玲 (90724500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 枝園忠彦 (30509451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 濱田龍正 (40933362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kosaka Mitsuko 小阪 美津子

KOSAKA MITSUKO 小阪 美津子

KOSAKA Mitsuko 小阪 美津子

Research Projects

Research Products

Co-Researchers

上肢リンパ地図がもたらす乳がん術後リンパ浮腫予防

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation and application of the regulatory mechanism of SPP1 gene in human cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cellular plasticity of OCT4 expressing somatic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Oct3/4 in retinal development and dieseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Key genes related to retinal development and diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

虹彩色素上皮細胞によるレンズ細胞への分化転換機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanism of Transdifferentiation in Regeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanisms of Transdifferentiation and Stabilization in Differentiation of Animal Tissue Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Immediate differentiation of neuronal cells from stem/progenitor-like cells in the avian iris tissues2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Architecture of the Subendothelial Elastic Fibers of Small Blood Vessels and Variations in Vascular Type and Size2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled42011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] /Iris pigment epithelium as a potential source for both basic biology and therapeutic applications for retinal regeneration/2008

Author(s)

Journal Title

Data Source

[Journal Article] Novel variants of Oct-3/4 gene expressed in mouse somatic cells2008

Kosaka Mitsuko 小阪美津子

KOSAKA MITSUKO 小阪美津子

KOSAKA Mitsuko 小阪美津子