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YANO Ikuko  矢野 育子

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Researcher Number 50273446
Other IDs
External Links
Affiliation (Current) 2025: 神戸大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help 2025: 神戸大学, 医学部附属病院, 教授
2018 – 2023: 神戸大学, 医学部附属病院, 教授
2016 – 2017: 神戸大学, 医学部附属病院, 准教授
2013 – 2015: 京都大学, 薬学研究科(研究院), 准教授
2014: 京都大学, 薬学研究科, 准教授 … More
2011: 京都大学, 大学院・薬学研究科, 准教授
2007 – 2011: Kyoto University, 薬学研究科, 准教授
2006: Kyoto University, Graduate School of Pharmaceutical Sciences, Associate Professor, 薬学研究科, 助教授
2005: 京都大学, 医学研究科, 技術職員
2002: 京大, 医学(系)研究科(研究院), 助手
1996 – 2001: Graduate School of Medicine, Kyoto University Instructor, 医学研究科, 助手
1999 – 2000: 京都大学, 大学院・医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / 応用薬理学・医療系薬学
Except Principal Investigator
応用薬理学・医療系薬学 / Applied pharmacology / Physical pharmacy / Medical pharmacy
Keywords
Principal Investigator
薬物動態 / NONMEM / 母集団解析 / PBPK / CYP3A5 / 免疫抑制剤 / パリペリドン / 新生児 / 妊婦 / リスペリドン … More / 生体肝移植 / タクロリムス / TDM / 薬学 / 薬剤反応性 / 薬理学 / 抗ウイルス薬 / 薬物動態解析 / ファーマコメトリクス / 周産期 / 乾燥ろ紙血 / LC-MS/MS / 抗精神病薬 / 生理学的薬物動態モデル / 抗てんかん薬 / 妊娠 / 薬物離脱症状 / 特殊集団 / PBPKモデル / フェンタニル / ブレクスピプラゾール / アルプラゾラム / 臨床 / 発達 / 小児 / トリクロエタノール / CYP2C19 / 腎移植 / 生理学薬物動態モデル / Transplantation therapy / P-glycoprotein / Calcineurin Activity / Cyclosporine / Tacrolimus / MONMEM / カルシニューリン / 母集団薬物動態解析 / 移植医療 / P-糖蛋白質 / カルシニューリン活性 / シクロスポリン / NAR / PK/PD解析 / ポピュレーション解析 / M&S / IMPDH / ミコフェノール酸 / 造血幹細胞移植 / M & S / 免疫抑制薬 / 遺伝学 / P-糖タンパク質 / 薬力学 / 薬物動態学 / 脳神経疾患 / 遺伝子 / 臨床薬物動態学 / オーダーメイド医療 / mTOR阻害剤 / 薬物相互作用 / 移植・再生医療 / OCT2 / OAT1 / シスプラチン / 腎障害 / 遺伝子発現 / 有機カチオン / 有機アニオン / 腎排泄 / 薬物トランスポータ / 眼圧 / ファーマコダイナミックス / フォーマコキネティックス / アセタゾラミド … More
Except Principal Investigator
CYP3A4 / CYP2C19 / CYP2C9 / P-glycoprotein / 尿細管分泌 / Caco-2 / LLC-PK_1 / 薬物動態 / 有機カチオントランスポータ / 有機アニオントランスポータ / Organic ion / Renal excretion / Detoxification system / Expression profile / Genetic polymorphism / Interindividual differences / Personalized pharmacotherapy / Drug transporter / 遺伝子発現 / 薬物相互作用 / 腎疾患 / 有機アニオン / 有機カチオン / ペプチド類似薬物 / カチオン性薬物 / アニオン性薬物 / オーダーメイド薬物療法 / 有機イオン / 腎排泄 / 解毒システム / 発現プロファイル / 遺伝子多型 / 固体間変動 / テーラーメイド薬物療法 / 薬物トランスポータ / tacrolimus / intestine / metabolism / transporter / bioavailability / タクロリムス / 小腸 / 代謝 / P-糖蛋白質 / トランスポータ / バイオアベイラビリティ / drug metabolism / p450 / non-linear pharmacokinetics / genetic polymorphism / population pharmacokinetics / phenytoin / 薬物代謝 / P450 / 非線形体内動態 / 遺伝的多型 / 母集団薬物速度論 / フェニトイン / cDNA cloning / Xenopus oocyte / transfection / organic cation transporter / organic ahion transporter / tubular secretion / drug transport / テトラエチルアンモニウム / メトトレキセート / 動物細胞安定発現系 / アフリカメガユル卵母細胞 / P・糖タンパク質 / cDNAクローニング / アフリカツメガエル卵母細胞 / トランスフェクション / P-糖タンパク質 / 有機カテオントランスポータ / 薬物輸送 / Kinetic analysis / Renal toxicity / Transcellular transport / beta-Lactam antibiotics / Peptide transporter / Cultured cells / LLC-PK_<1-> / 速度論的解析 / 腎毒性 / 経細胞輸送 / β-ラクタム系抗生物質 / ペプチド輸送系 / 培養細胞 / 機械学習 / パラメータ推定 / 母集団解析 / 拡張最小二乗法 / 個体間変動 / 遺伝的数式プログラミング / 遺伝的アルゴリズム / 共変量モデル / 母集団薬物動態解析 / 薬理遺伝学 / 臨床薬理学 / ELISA測定法 / カルシニューリン / 薬効評価 / 抗リン酸化ペプチド抗体 / 移植・再生医療 / 薬物認識 / 薬物送達システム / ペプチドトランスポータ Less
  • Research Projects

    (20 results)
  • Research Products

    (166 results)
  • Co-Researchers

    (23 People)
  •  バルガンシクロビルの精密投与設計のためのファーマコメトリクスPrincipal Investigator

    • Principal Investigator
      矢野 育子
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Kobe University
  •  周産期母児における抗精神病薬治療の適正化のためのファーマコメトリクスPrincipal Investigator

    • Principal Investigator
      矢野 育子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Kobe University
  •  Pharmacometrics of newer antiepileptics for the optimization in pregnant womenPrincipal Investigator

    • Principal Investigator
      Yano Ikuko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Kobe University
  •  Pharmacometrics in the clinical setting for dosage adjustment of special populationsPrincipal Investigator

    • Principal Investigator
      Yano Ikuko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kobe University
  •  Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid and Individualized TherapyPrincipal Investigator

    • Principal Investigator
      Yano Ikuko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyoto University
  •  Full-automatic PopPK modeling utilizing an evolutionary algorithm

    • Principal Investigator
      YAMASHITA Fumiyoshi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyoto University
  •  Population pharmacokinetics and pharmacodynamics and individualized therapy in patients with refractory epilepsyPrincipal Investigator

    • Principal Investigator
      YANO Ikuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyoto University
  •  Dosage schedule based on pharmacokinetic and pharmacodynamic interaction of immunosuppressantsPrincipal Investigator

    • Principal Investigator
      YANO Ikuko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyoto University
  •  Standardization of tailor-made chemotherapy based on pharmacokinetics and pharmacogenomics

    • Principal Investigator
      ISHIGURO Hiroshi
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kyoto University
  •  抗リン酸化ペプチド抗体を用いた高感度カルシニューリン活性測定法の開発と臨床応用

    • Principal Investigator
      乾 賢一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      Kyoto University
  •  Population Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors and Development of Individualized TherapyPrincipal Investigator

    • Principal Investigator
      YANO Ikuko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyoto University
  •  免疫抑制剤の体内動態・薬効の母集団速度論的解析と個別化処方設計支援システムの開発Principal Investigator

    • Principal Investigator
      矢野 育子
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kyoto University
  •  Evaluation of drug interaction and interindividual differences of renal drug excretion based on the genetic polymorphism analysis

    • Principal Investigator
      INUI Ken-ichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      KYOTO UNIVERSTTY
  •  病態時における薬物腎排泄の変動とその分子機構に基づく科学的投与設計の構築Principal Investigator

    • Principal Investigator
      矢野 育子
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kyoto University
  •  薬物トランスポータ分子認識を利用した薬物動態制御システムの構築

    • Principal Investigator
      INUI Ken-ichi
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  Analysis of barrier function of intestinal drug-metabolizing enzymes and transporters

    • Principal Investigator
      YUKIYA Hashimoto
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
      Kyoto University
  •  Development of novel systems for evaluation and prediction of drug inteactions based on the reconstruction of drug excretion systems in vitro.

    • Principal Investigator
      INUI Ken-ichi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      KYOTO UNIVERSITY
  •  Individual dosage regimen based on population pharmacokinetics and genotyping of drug metabolizing enzymes

    • Principal Investigator
      HASHIMOTO Yukiya
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      KYOTO UNIVERSITY
  •  緑内障治療剤投与の適正化を目指した薬物体内動態・薬効の母集団解析Principal Investigator

    • Principal Investigator
      矢野 育子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kyoto University
  •  Kietic analysis and evaluation of drug absorption and excretion using cultured cells.

    • Principal Investigator
      INUI Ken-ichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      KYOTO UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 医療薬学第6版2014

    • Author(s)
      石塚良子、乾 賢一、奥村勝彦、尾崎淳子、桂 敏也、木下 淳、駒田富佐夫、高山 明、谷川原祐介、寺田智祐、中尾 誠、西口工司、橋口正行、望月眞弓、本橋秀之、安原眞人、矢野育子、矢野義孝、若杉博子
    • Total Pages
      478
    • Publisher
      廣川書店
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Book] 最新薬剤学第10版2012

    • Author(s)
      矢野育子(分担執筆)
    • Total Pages
      605
    • Publisher
      廣川書店
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Book] Important drug interactions for clinical oncologists. In "Frontiers in Drug Design and Discovery vol.4" ed. By G.W. Caldwell, A. Z. Yan, and M. I. Choudhary2009

    • Author(s)
      Ishiguro, H., Yano, I., Toi, M.
    • Publisher
      Bentham Science Publishers Ltd
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Book] Pharmacogenomic considerations in breast cancer management. In "Frontiers in Drug Design and Discovery vol. 4" ed. By G.W. Caldwell, A. Z. Yan, and M. I. Choudhary2009

    • Author(s)
      Ishiguro, H., Yano, I., and Toi, M
    • Publisher
      Bentham Science Publishers Ltd
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Book] Bentham Frontiers in Drug Design & Discovery(Important Drug Interactions for Clinical Oncologists)2009

    • Author(s)
      Ishiguro H, Yano I, Toi M
    • Publisher
      Science Publishers Ltd
    • Data Source
      KAKENHI-PROJECT-19590533
  • [Book] Pharmacogenomic Considerations(Breast Cancer Management, in Frontiers in Drug Design & Discovery)2009

    • Author(s)
      Ishiguro H, Yano I, Toi M.
    • Publisher
      Bentham Science Publishers Ltd
    • Data Source
      KAKENHI-PROJECT-19590533
  • [Book] Evolution of living-donor liver transplantation2008

    • Author(s)
      Yano, I., Masuda, S., Inui, K.
    • Total Pages
      336
    • Publisher
      Thomson Reuters
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Book] 8.2 Therapeutic drug monitoring and individualized therapy with tacrolimus in recipients of living-donor liver transplantation. In "Evolution of living-donor liver transplantation" ed. By K. Tanaka, Y. Inomata, S. Uemoto, and T. Kiuchi2008

    • Author(s)
      Yano, I., Masuda, S., and Inui, K
    • Publisher
      Thomson Reuters
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Book] 薬剤師が変える薬物治療2-安全ながん治療とテーラーメイド医療に向けて-2007

    • Author(s)
      矢野育子(分担)
    • Total Pages
      238
    • Publisher
      じほう
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590121
  • [Book] "医療薬学第4版"、第4章 薬物療法と処方 4.5臓器移植時の薬物療法と処方.2005

    • Author(s)
      矢野育子ほか
    • Publisher
      廣川書店
    • Data Source
      KAKENHI-PROJECT-17590121
  • [Journal Article] Pharmacokinetics of Brexpiprazole, Quetiapine, Risperidone, and Its Active Metabolite Paliperidone in a Postpartum Woman and Her Baby2024

    • Author(s)
      Konishi Toru、Kitahiro Yumi、Fujiwara Naoko、Yamamoto Kazuhiro、Hashimoto Mari、Ito Takahiro、Itohara Kotaro、Fujioka Kazumichi、Imafuku Hitomi、Otsuka Ikuo、Omura Tomohiro、Yano Ikuko
    • Journal Title

      Therapeutic Drug Monitoring

      Volume: - Issue: 5 Pages: 687-691

    • DOI

      10.1097/ftd.0000000000001197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Journal Article] Physiologically‐based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate2023

    • Author(s)
      Mahdy Walaa Y. B.、Yamamoto Kazuhiro、Ito Takahiro、Fujiwara Naoko、Fujioka Kazumichi、Horai Tadasu、Otsuka Ikuo、Imafuku Hitomi、Omura Tomohiro、Iijima Kazumoto、Yano Ikuko
    • Journal Title

      Clinical and Translational Science

      Volume: 16 Issue: 4 Pages: 618-630

    • DOI

      10.1111/cts.13473

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Journal Article] Upfront use of first-/second-generation EGFR-TKI followed by osimertinib shows better prognosis than upfront osimertinib therapy in Japanese patients with non-small-cell lung cancer with exon 19 deletion: A single-center retrospective study.2023

    • Author(s)
      Hori T, Yamamoto K, Ito T, Ikushima S, Omura T, Yano I
    • Journal Title

      Biol. Pharm. Bull

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Journal Article] ALBI Grade Is a Predictive Factor of Lenvatinib Treatment Discontinuation due to Adverse Events in Hepatocellular Carcinoma2023

    • Author(s)
      ENOMOTO DAICHI、YAMAMOTO KAZUHIRO、MATSUMOTO YUKI、MORIOKA ASAMI、OMURA TOMOHIRO、KOMATSU SHOHEI、YANO YOSHIHIKO、FUKUMOTO TAKUMI、YANO IKUKO
    • Journal Title

      Anticancer Research

      Volume: 43 Issue: 3 Pages: 1317-1323

    • DOI

      10.21873/anticanres.16279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Journal Article] Association of<i>STAT3, CYP3A5</i>, and<i>ABCG2</i>Polymorphisms With Osimertinib-induced Adverse Events in NSCLC Patients2023

    • Author(s)
      TANDA MASAAKI、YAMAMOTO KAZUHIRO、HORI TOMOKI、NISHIGUCHI HIROKI、YAGI MIKI、SHIMIZU MICHIKO、KONISHI TORU、OZAKI TOMONORI、YOSHIOKA NATSUE、TACHIHARA MOTOKO、ITO TAKEFUMI、IKUSHIMA SHIGEKI、OMURA TOMOHIRO、YANO IKUKO
    • Journal Title

      Anticancer Research

      Volume: 43 Issue: 4 Pages: 1775-1783

    • DOI

      10.21873/anticanres.16331

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06697, KAKENHI-PROJECT-20K08518
  • [Journal Article] Effects of Proton Pump Inhibitors on Survival Outcomes in Patients with Metastatic or Unresectable Urothelial Carcinoma Treated with Pembrolizumab2022

    • Author(s)
      Kunimitsu Yoko、Morio Kayoko、Hirata Sachi、Yamamoto Kazuhiro、Omura Tomohiro、Hara Takuto、Harada Kenichi、Fujisawa Masato、Yano Ikuko
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 45 Issue: 5 Pages: 590-595

    • DOI

      10.1248/bpb.b21-00939

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2022-05-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] Safety and Efficacy of Bis-Glyceryl Ascorbate as Prophylaxis for Hand-Foot Skin Reaction: A Single-Arm, Open-Label Phase I/II Study (DGA Study)2022

    • Author(s)
      Yamamoto Kazuhiro、Nishiyama Satoshi、Kunisada Makoto、Iida Masashi、Ito Takahiro、Ioroi Takeshi、Makimoto Hiroo、Omura Tomohiro、Harada Kenichi、Fujisawa Masato、Nishigori Chikako、Yano Ikuko
    • Journal Title

      The Oncologist

      Volume: 27 Issue: 5 Pages: e384-e392

    • DOI

      10.1093/oncolo/oyab067

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219, KAKENHI-PROJECT-21H04173
  • [Journal Article] STAT3 polymorphism associates with mTOR inhibitor-induced interstitial lung disease in patients with renal cell carcinoma2022

    • Author(s)
      Kazuhiro Yamamoto, Takeshi Ioroi, Kazuaki Shinomiya, et al.
    • Journal Title

      Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

      Volume: - Issue: 1 Pages: 11-23

    • DOI

      10.3727/096504022x16418911579334

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07191, KAKENHI-PROJECT-19K07219, KAKENHI-PROJECT-20K09560
  • [Journal Article] Effectiveness of pharmacist intervention for deprescribing potentially inappropriate medications: a prospective observational study2022

    • Author(s)
      Kimura Takeshi、Fujita Misa、Shimizu Michiko、Sumiyoshi Kasumi、Bansho Saho、Yamamoto Kazuhiro、Omura Tomohiro、Yano Ikuko
    • Journal Title

      Journal of Pharmaceutical Health Care and Sciences

      Volume: 8 Issue: 1 Pages: 12-12

    • DOI

      10.1186/s40780-022-00243-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] Sustained Improvements in Antimicrobial Therapy and Clinical Outcomes following a Pharmacist-Led Antimicrobial Stewardship Intervention: Uncontrolled Before?After Study2022

    • Author(s)
      Uda Atsushi、Ebisawa Kei、Sakon Hitomi、Kusuki Mari、Izuta Rie、Yahata Mariko、Yano Ikuko、Miyara Takayuki
    • Journal Title

      Journal of Clinical Medicine

      Volume: 11 Issue: 3 Pages: 566-566

    • DOI

      10.3390/jcm11030566

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] Population pharmacokinetics of everolimus in adult liver transplant patients: Comparison to tacrolimus disposition and extrapolation to pediatrics2022

    • Author(s)
      Kotaro Itohara, Ikuko Yano, Shunsaku Nakagawa, Mitsuhiro Sugimoto, Machiko Hirai, Atsushi Yonezawa, Satoshi Imai, Takayuki Nakagawa, Daiki Hira, Takashi Ito, Koichiro Hata, Etsuro Hatano, Tomohiro Terada, Kazuo Matsubara
    • Journal Title

      Clinical and Translational Science

      Volume: 15 Issue: 11 Pages: 2652-2662

    • DOI

      10.1111/cts.13389

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06711, KAKENHI-PROJECT-22K06697
  • [Journal Article] Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients2022

    • Author(s)
      Itohara Kotaro、Yano Ikuko、Nakagawa Shunsaku、Yonezawa Atsushi、Omura Tomohiro、Imai Satoshi、Nakagawa Takayuki、Sawada Atsuro、Kobayashi Takashi、Tochio Akira、Sakai Kaoru、Taura Kojiro、Ogawa Osamu、Matsubara Kazuo
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 42 Pages: 100423-100423

    • DOI

      10.1016/j.dmpk.2021.100423

    • NAID

      210000173091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] Association of sunitinib concentration and clinical outcome in patients with metastatic renal cell carcinoma treated with a 2‐week‐on and 1‐week‐off schedule2021

    • Author(s)
      Ito Takahiro、Yamamoto Kazuhiro、Furukawa Junya、Harada Kenichi、Fujisawa Masato、Omura Tomohiro、Yano Ikuko
    • Journal Title

      Journal of Clinical Pharmacy and Therapeutics

      Volume: 47 Issue: 1 Pages: 81-88

    • DOI

      10.1111/jcpt.13517

    • NAID

      120007188917

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219, KAKENHI-PROJECT-21H04173
  • [Journal Article] Ibuprofen gargle for chemo- or Chemoradiotherapy-induced Oral Mucositis: a feasibility study2020

    • Author(s)
      Ioroi Takeshi、Kiyota Naomi、Imamura Yoshinori、Tanda Masaaki、Aoki Shiori、Okuno Mamoru、Yamamoto Kazuhiro、Sasaki Ryohei、Nibu Ken-ichi、Minami Hironobu、Hirai Midori、Yano Ikuko
    • Journal Title

      Journal of Pharmaceutical Health Care and Sciences

      Volume: 6 Issue: 1 Pages: 12-12

    • DOI

      10.1186/s40780-020-00168-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] Model-based assessment of pharmacokinetic changes of sunitinib, tacrolimus, and everolimus in a patient with metastatic renal cell carcinoma after renal transplantation2020

    • Author(s)
      Ito Takahiro、Yamamoto Kazuhiro、Ogawa Satoshi、Furukawa Junya、Harada Kenichi、Fujisawa Masato、Omura Tomohiro、Yano Ikuko
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 35 Issue: 5 Pages: 405-409

    • DOI

      10.1016/j.dmpk.2020.05.006

    • NAID

      120006894027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] Relationship Between Tramadol Response and Cancer Cachexia: A Retrospective Cohort Study2020

    • Author(s)
      Morio Kayoko、Yamamoto Kazuhiro、Yano Ikuko
    • Journal Title

      American Journal of Hospice and Palliative Medicine?

      Volume: 38 Issue: 3 Pages: 276-282

    • DOI

      10.1177/1049909120945570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Journal Article] 治療薬物モニタリング(TDM)2019

    • Author(s)
      阪上倫行,山本和宏,矢野育子
    • Journal Title

      診断と治療

      Volume: 107 Pages: 173-179

    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Journal Article] Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model2019

    • Author(s)
      Yamamoto Kazuhiro、Fukushima Sachiyo、Mishima Yui、Hashimoto Mari、Yamakawa Kei、Fujioka Kazumichi、Iijima Kazumoto、Yano Ikuko
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 34 Issue: 6 Pages: 400-402

    • DOI

      10.1016/j.dmpk.2019.09.002

    • NAID

      120006775971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07219, KAKENHI-PROJECT-18K15710
  • [Journal Article] A Minimal PBPK Model for Tacrolimus in Living-Donor Liver Transplantation : Perspectives related to Liver Regeneration and CYP3A5 genotype.2019

    • Author(s)
      Itohara K, Yano I, Tsuzuki T, Uesugi M, Nakagawa S, Yonezawa A, Okajima H, Kaido T, Uemoto S, Matsubara K.
    • Journal Title

      CPT : Pharmacometrics & Systems Pharmacology

      Volume: 8 Issue: 8 Pages: 587-595

    • DOI

      10.1002/psp4.12420

    • Description
      In press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H00394, KAKENHI-PROJECT-18H00443, KAKENHI-PROJECT-19K07219, KAKENHI-PROJECT-17K08446
  • [Journal Article] A Minimal PBPK Model for Tacrolimus in Living-Donor Liver Transplantation: Perspectives related to Liver Regeneration and CYP3A5 Genotype.2019

    • Author(s)
      Itohara K, Yano I, Tsuzuki T, Uesugi M, Nakagawa S, Yonezawa A, Okajima H, Kaido T, Uemoto S, Matsubara K.
    • Journal Title

      CPT: Pharmacometrics & Systems Pharmacology

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Journal Article] Pharmacokinetic and Pharmacodynamic Markers of Mycophenolic Acid Associated with Effective Prophylaxis for Acute Graft-Versus-Host Disease and Neutrophil Engraftment in Cord Blood Transplant Patients2018

    • Author(s)
      Yoshimura Kazuaki、Yano Ikuko、Yamamoto Takashi、Kondo Tadakazu、Kawanishi Misaki、Isomoto Yui、Yonezawa Atsushi、Takaori-Kondo Akifumi、Matsubara Kazuo
    • Journal Title

      Biol. Blood Marrow Transplant.

      Volume: - Issue: 7 Pages: 1441-1448

    • DOI

      10.1016/j.bbmt.2018.01.040

    • NAID

      120006501237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08400, KAKENHI-PROJECT-17K08446
  • [Journal Article] Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study.2018

    • Author(s)
      Ito T, Yamamoto K, Ohsawa F, Otsuka I, Hishimoto A, Sora I, Hirai M, Yano I.
    • Journal Title

      Journal of Pharmaceutical Health Care and Sciences

      Volume: 4 Issue: 1 Pages: 28-28

    • DOI

      10.1186/s40780-018-0126-y

    • NAID

      120006543322

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K08400, KAKENHI-PROJECT-16K08401, KAKENHI-PROJECT-16K19765
  • [Journal Article] Pharmacokinetics and Pharmacodynamics of Once-Daily Tacrolimus Compared With Twice-Daily Tacrolimus in the Early Stage After Living Donor Liver Transplantation.2018

    • Author(s)
      Iwasaki M, Yano I, Fukatsu S, Hashi S, Yamamoto Y, Sugimoto M, Fukudo M, Masuda S, Nakagawa S, Yonezawa A, Kaido T, Uemoto S, Matsubara K.
    • Journal Title

      Ther Drug Monit

      Volume: 40 Issue: 6 Pages: 675-681

    • DOI

      10.1097/ftd.0000000000000551

    • NAID

      120006559313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08446, KAKENHI-PROJECT-18H02588, KAKENHI-PROJECT-16K08400, KAKENHI-PROJECT-18H00419
  • [Journal Article] 小児におけるトリクロホスの投与量の最適化2017

    • Author(s)
      井上美帆,佐藤博貴,糸原光太郎,加藤祐子,石井祥代,伊藤由起,中平有紀, 那須民江,上島通浩,矢野育子,松原和夫,佐和貞治,橋本悟
    • Journal Title

      臨床薬理の進歩

      Volume: 38 Pages: 71-78

    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Journal Article] Population pharmacokinetics and pharmacodynamics of mycophenolic acid using the prospective data in patients undergoing hematopoietic stem cell transplantation2017

    • Author(s)
      Yoshimura K、Yano I、Yamamoto T、Kawanishi M、Isomoto Y、Yonezawa A、Kondo T、Takaori-Kondo A、Matsubara K
    • Journal Title

      Bone Marrow Transplantation

      Volume: 53 Issue: 1 Pages: 44-51

    • DOI

      10.1038/bmt.2017.213

    • NAID

      120006463593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Journal Article] 薬剤師主導のバンコマイシン処方設計に向けた取り組み2017

    • Author(s)
      住吉霞美,山本和宏,矢野育子
    • Journal Title

      医薬ジャーナル

      Volume: 53 Pages: 2315-2319

    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Journal Article] Population pharmacokinetics of topiramate in Japanese pediatric and adult patients with epilepsy using routinely monitored data.2017

    • Author(s)
      Takeuchi M, Yano I, Ito S, Sugimoto M, Yamamoto S, Yonezawa A, Ikeda A,Matsubara K
    • Journal Title

      Therapeutic Drug Monitoring

      Volume: 39 Issue: 2 Pages: 124-131

    • DOI

      10.1097/ftd.0000000000000383

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-26293209, KAKENHI-PROJECT-16K08400, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-17K08446
  • [Journal Article] Population pharmacokinetics of everolimus in relation to clinical outcomes in patients with advanced renal cell carcinoma.2016

    • Author(s)
      Tanaka A, Yano I, Shinsako K, Sato E, Fukudo M, Masuda S, Yamasaki T, Kamba T, Ogawa O, Matsubara K
    • Journal Title

      Ther Drug Monit

      Volume: 38 Issue: 6 Pages: 663-669

    • DOI

      10.1097/ftd.0000000000000344

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08400, KAKENHI-PROJECT-16K08902
  • [Journal Article] Effect of vitamin K2 on the anticoagulant activity of warfarin during the perioperative period of catheter ablation: Population analysis of retrospective clinical data.2016

    • Author(s)
      Zhou, Zhi; Yano, Ikuko; Odaka, Sumiko; Morita, Yosuke; Shizuta, Satoshi; Hayano, Mamoru; Kimura, Takeshi; Akaike, Akinori; Inui, Ken-ichi; Matsubara, Kazuo
    • Journal Title

      J Pharm Health Care Sci.

      Volume: 2 Issue: 1 Pages: 17-17

    • DOI

      10.1186/s40780-016-0053-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14962, KAKENHI-PROJECT-16K08400
  • [Journal Article] Sensitive and validated LC-MS/MS methods to evaluate mycophenolic acid pharmacokinetics and pharmacodynamics in hematopoietic stem cell transplant patients.2015

    • Author(s)
      Kawanishi, M., Yano, I., Yoshimura, K., Yamamoto, T., Hashi, S., Masuda, S., Kondo, T., Takaori-Kondo, A., Matsubara, K.
    • Journal Title

      Biomed. Chromatogr.

      Volume: 印刷中 Issue: 9 Pages: 1309-1316

    • DOI

      10.1002/bmc.3423

    • NAID

      120005676648

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Journal Article] Pharmacokinetics and pharmacodynamics of mycophenolic acid in Nagase analbuminemic rats: Evaluation of protein binding effects using the modeling and simulation approach.2015

    • Author(s)
      Yoshimura, K., Yano, I., Kawanishi, M., Nakagawa, S., Yonezawa, A., Matsubara, K.
    • Journal Title

      Drug Metab. Pharmacokinet.

      Volume: 30 Issue: 6 Pages: 441-448

    • DOI

      10.1016/j.dmpk.2015.10.004

    • NAID

      50014429985

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Journal Article] Multiple linear regression analysis indicates association of P-glycoprotein substrate or inhibitor character with bitterness intensity, measured with a sensor2015

    • Author(s)
      Kentaro Yano, Suzune Mita, Kaori Morimoto, Tamami Haraguchi, Hiroshi Arakawa, Miyako Yoshida, Fumiyoshi Yamashita, Takahiro Uchida, Takuo Ogihara
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 104 Issue: 9 Pages: 2789-2794

    • DOI

      10.1002/jps.24232

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-23136102, KAKENHI-PROJECT-24590667, KAKENHI-PROJECT-25670073
  • [Journal Article] Monitoring mycophenolate mofetil is necessary for the effective prophylaxis of acute graft versus host disease after cord blood transplantation.2015

    • Author(s)
      Arai, Y., Kondo, T., Kitano, T., Hishizawa, M., Yamashita, K., Kadowaki, N., Yamamoto, T., Yano, I., Matsubara, K., Takaori-Kondo, A.
    • Journal Title

      Bone Barrow Transplant.

      Volume: 50 Issue: 2 Pages: 312-314

    • DOI

      10.1038/bmt.2014.258

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Journal Article] Assessment of four methodologies (MEIA, CLIA, ACMIA, and FIA-MS/MS) for measuring tacrolimus blood concentration in Japanese liver transplant patients.2014

    • Author(s)
      Hashi S, Masuda S, Kikuchi M, Uesugi M. Yano I, Omura T, Yonezawa A, Fujimoto Y, Ogawa K, Kaido T, Uemoto S, Matsubara K
    • Journal Title

      Transplant Proc.

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Journal Article] Effectiveness of everolimus in combination with cyclosporine as treatment for chronic rejection in a pediatric patient undergoing liver transplantation.2014

    • Author(s)
      Sato E, Hashi S, Taniguchi R, Yano I, Matsubara K, Ogawa E, Yoshizawa A, Okamoto S, Uemoto S, Masuda S
    • Journal Title

      Jpn. J. Ther. Drug Monit.

      Volume: 31 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Journal Article] 非小細胞肺がん患者に対する簡易懸濁法を用いたエルロチニブ投与に関する検討2013

    • Author(s)
      髙田哲也, 池見泰明, 福土将秀, 杉本充弘, 石橋直哉, 小林政彦, 矢野育子, 金 永学, 三嶋理晃, 芦原英司, 松原和夫
    • Journal Title

      医療薬学

      Volume: 39 Pages: 565-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Journal Article] Impact of P-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs in knockout mouse models.2013

    • Author(s)
      Nakanishi H, Yonezawa A, Matsubara K, Yano I.
    • Journal Title

      Eur J Pharmacol

      Volume: 710 Issue: 1-3 Pages: 20-28

    • DOI

      10.1016/j.ejphar.2013.03.049

    • NAID

      120005289852

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25136710, KAKENHI-PROJECT-25460210
  • [Journal Article] Significance of trough monitoring for tacrolimus blood concentration and calcineurin activity in adult patients undergoing primary living-donor liver transplantation2012

    • Author(s)
      Yano I, Masuda S, Egawa H, Sugimoto Y, Fukudo M, Yoshida Y, Hashi S, Yoshizawa A, Ogura Y, Ogawa K, Mori A, Kaido T, Uemoto S, Inui K
    • Journal Title

      Eur J Clin Pharmacol

      Volume: 68(3) Issue: 3 Pages: 259-266

    • DOI

      10.1007/s00228-011-1129-x

    • NAID

      120003988188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] Degree of freezing does not affect efficacy of frozen gloves for prevention of docetaxel-induced nail toxicity in breast cancer patients2012

    • Author(s)
      Yano I, Ishiguro H, et al
    • Journal Title

      Supportive Care in Cancer

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring2012

    • Author(s)
      Shibata M, Hashi S, Nakanishi H, Masuda S, Katsura T, Yano I
    • Journal Title

      Biomed Chromatogr

      Volume: (in press) Issue: 12 Pages: 1519-1528

    • DOI

      10.1002/bmc.2726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156, KAKENHI-PROJECT-23390138
  • [Journal Article] Degree of freezing does not affect efficacy of frozen gloves for prevention of do cetaxel-induced nail toxicity in breast cancer patients2011

    • Author(s)
      Ishiguro H(1番目), Yano I, Yanagihara K, et al
    • Journal Title

      Support Care Cancer

      Volume: (in press) Issue: 9 Pages: 2017-2024

    • DOI

      10.1007/s00520-011-1308-4

    • NAID

      120004873705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590533, KAKENHI-PROJECT-21590156
  • [Journal Article] Heterozygous variants of multidrug and toxin extrusions(MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients2010

    • Author(s)
      Toyama K, Yonezawa A, Tsuda M, Masuda S, Yano I, Terada T, Osawa R, Katsura T, Hosokawa M, Fujimoto S, Inagaki N, Inui K
    • Journal Title

      Pharmacogenet. Genomics

      Volume: 20(2) Issue: 2 Pages: 135-138

    • DOI

      10.1097/fpc.0b013e328335639f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156, KAKENHI-PROJECT-22390029
  • [Journal Article] A transient increase of calcineurin phosphatase activity in living-donor kidney transplant recipients with acute rejection2010

    • Author(s)
      Fukudo M, Yano I, Katsura T, Ito N, Yamamoto S, Kamoto T, Ogawa O, Inui K
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 25(5) Pages: 411-417

    • NAID

      10027583568

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] Population analysis of myelosuppression profiles using routine clinical data after combination cancer chemotherapy2009

    • Author(s)
      Yano, Y., Kodawara, T., Hongo, H., Yano, I., Kishi, Y., Takahashi, J., Inui, K
    • Journal Title

      J. Pharm. Sci (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Prospective evaluation of the Bayesian method for individualizing tacrolimus dose early after living-donor liver transplantation2009

    • Author(s)
      Fukudo, M., Yano, I., Shinsako, K., Katsura, T., Takada, Y., Uemoto, S., Inui, K.
    • Journal Title

      J. Clin. Phamacol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Prospective evaluation of the Bayesian method for individualizing tacrolimus dose early after living-donor liver transplantation2009

    • Author(s)
      Fukudo M, Yano I, Shinsako K, Katsura T, Takada Y, Uemoto S, Inui K
    • Journal Title

      J Clin Phamacol

      Volume: 49(7) Issue: 11 Pages: 789-797

    • DOI

      10.1002/jps.21731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] Important Drug Interactions for Clinical Oncologists2009

    • Author(s)
      Ishiguro H, Yano I, Toi M
    • Journal Title

      Frontiers in Drug Design & Discovery 4

      Pages: 97-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590533
  • [Journal Article] A retrospective analysis of vancomycin pharmacokinetics in Japanese cancer and non-cancer patients based on routine trough monitoring data. Biol2009

    • Author(s)
      Omote, S., Yano, Y., Hashida, T., Masuda, S., Yano, I., Katsura, T., Inui, K
    • Journal Title

      Pharm. Bull 32(1)

      Pages: 99-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Prospective evaluation of the Bayesian method for individualizing tacrolimus dose early after living-donor liver transplantation.2009

    • Author(s)
      Fukudo, M., Yano, I., et al.
    • Journal Title

      J. Clin. Phamacol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] A larger dosage is needed for everolimus than sirolimus to maintain the same blood concentration in two pancreatic islet transplant patients with tacrolimus. Drug Metab.2009

    • Author(s)
      Sato, E., Yano, I., Shimomura, M., Masuda, S., Toshiya Katsura, T., Matsumoto, S., Okitsu, T., Iwanaga, Y., Shinji Uemoto, S., Inui , K
    • Journal Title

      Pharmacokinet 24(2)

      Pages: 175-179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] 薬物トランスポーター活用ライブラリー 機能・輸送基質から創薬・臨床応用まで(羊土社)2009

    • Author(s)
      矢野育子
    • Journal Title

      羊土社

      Pages: 169-171

    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] A larger dosage is needed for everoliimus than sirolimus to maintain the same blood concentration in two pancreatic islet transplant patients with tacrolimus.2009

    • Author(s)
      Sato, E., Yano, I., et al.
    • Journal Title

      Drug Metab. Pharmacokinet.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Effect of itraconazole on the pharmacokinetics of everolimus administered by different routes in rats2009

    • Author(s)
      Yokomasu A, Yano I, Sato E, Masuda S, Katsura T, Inui K
    • Journal Title

      Biopharm Drug Disp

      Volume: 30(9) Issue: 9 Pages: 517-523

    • DOI

      10.1002/bdd.687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] Pharmacogenomic Considerations in Breast Cancer Management2009

    • Author(s)
      Ishiguro H, Yano I, Toi M
    • Journal Title

      Frontiers in Drug Design & Discovery 4

      Pages: 122-134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590533
  • [Journal Article] 造血幹細胞移植患者におけるカルシニューリン阻害剤とアゾール系抗真菌剤の薬物動態学的相互作用の評価2009

    • Author(s)
      高嶋美季、谷口理沙、矢野育子、甲野貴久、橋田亨、増田智先、石川隆之、内山卓、乾賢一
    • Journal Title

      医療薬学 35(4)

      Pages: 233-239

    • NAID

      10025973217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Population analysis of myelosuppression profiles using routine clinical data after combination cancer chemotherapy.2009

    • Author(s)
      Yano, Y., et al.
    • Journal Title

      J.Pharm,Sci. 98

      Pages: 4402-4412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Journal Article] Pharmacodynamic monitoring of calcineurin phosphatase activity in transplant patients treated with calcineurin inhibitors2008

    • Author(s)
      Yano, I.
    • Journal Title

      Drug Metab. Pharmacokinet 23(3)

      Pages: 150-157

    • NAID

      10024188106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Effect of intestinal and hepatic first-pass extraction on the pharmacokinetics of everolimus in rats2008

    • Author(s)
      Yokomasu, A., Yano, I., Sato, E., Masuda, S., Toshiya Katsura, T., Inui, K
    • Journal Title

      Drug Metab. Pharmacokinet 23(6)

      Pages: 469-475

    • NAID

      10025722222

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] 成人難治性てんかん患者におけクロバザムおよび活性代謝物の体内動態に関する解析2008

    • Author(s)
      安田幸代、矢野育子、北村朋子、橋田亨、木下真幸子、池田昭夫、高橋良輔、乾賢一
    • Journal Title

      TDM研究 25(4)

      Pages: 165-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients2008

    • Author(s)
      Fukudo, M., Yano, I., Yoshimura, A., Masuda, S., Uesugi, M., Hosohata, K., Katsura, T., Ogura, Y., Oike, F., Takada, Y., Uemoto, S., Inui, K
    • Journal Title

      Pharmacogenet. Genomics 18(5)

      Pages: 413-423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] カルシニューリン阻害剤の体内動態と薬効の速度論的解析に基づく個別化投与設計法2008

    • Author(s)
      矢野育子、福土将秀、増田智先、小倉靖弘、尾池文隆、田中紘一、乾賢一
    • Journal Title

      臨床薬理の進歩2008 29

      Pages: 113-119

    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Effect of intestinal and hepatic first-pass extraction on the pharrmacokinetics of everolimus in rats.2008

    • Author(s)
      Yokomasu, A., Yano, I., et al.
    • Journal Title

      Drug Metab. Pharmacokinet. 23

      Pages: 469-475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] タクロリムス血中濃度の調整メカニズム2008

    • Author(s)
      矢野育子、乾賢一
    • Journal Title

      今日の移植 21(1)

      Pages: 17-23

    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Impact of intestinal MDR1 and CYP3A5 on the oral clearance of tacrolimus in adult living-donor liver transplant patients.2008

    • Author(s)
      Fukudo, M., Yano, I., et. al.
    • Journal Title

      Pharmacogenet. Genomics (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Pharmacokinetics and Pharmacodynamics of Paclitaxel with Carboplatin or Gemcitabine and Effects of CYP3A5 and MDR1 polymorphisms in Patients with Urogenital Cancers.2007

    • Author(s)
      Jiko, M., Yano, I., et. al.
    • Journal Title

      Int. J. Clin. Oncol. 12

      Pages: 284-290

    • NAID

      10020000038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Pharmacokinetics andpharmacodynamics of paclitaxel with carboplatin or gemcitabine and effects of CYP3A5 and MDR1 polymorphisms in patients with urogenital cancers2007

    • Author(s)
      Jiko, M., Yano, I., Sato, E., Takahashi, K., Motohashi, H., Masuda, S., Okuda, M., Ito, N., Nakamura, E., Segawa, T., Kamoto, T., Ogawa, O., Inui, K
    • Journal Title

      Int. J. Clin. Oncol 12(4)

      Pages: 284-290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] EMIT法によるミコフェノール酸血中濃度測定とHPLC法との比較による血中濃度評価2007

    • Author(s)
      古俵孝明、吉田優子、澤田京子、増田智先、矢野育子、乾賢一
    • Journal Title

      医療薬学 33(9)

      Pages: 804-808

    • NAID

      110006390977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Distinct effects of omeprazole and rabeprazole on the tacrolimus blood concentration in a kidney transplant recipient.2007

    • Author(s)
      Takahashi, K., Yano, I., et. al.
    • Journal Title

      Drug Metab. Pharmacokinet. 22

      Pages: 441-444

    • NAID

      10020163636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] Distinct effects of omeprazole and rabeprazole on the tacrolimus blood concentration in a kidney transplant recipient. Drug Metab2007

    • Author(s)
      Takahashi, K., Yano, I., Fukuhara, Y., Katsura, T., Takahashi, T., Ito, N., Yamamoto, S., Ogawa, O., Inui, K
    • Journal Title

      Pharmacokinet 22(6)

      Pages: 441-444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Journal Article] 生体肝移植のTDM2006

    • Author(s)
      矢野育子, 乾 賢一
    • Journal Title

      TDM研究 23(2)

      Pages: 63-64

    • Data Source
      KAKENHI-PROJECT-17590121
  • [Journal Article] 生体肝移植症例におけるカルシニューリン活性の測定に基づ<薬効評価と個別化投与設計2006

    • Author(s)
      矢野育子ほか
    • Journal Title

      月刊薬事 48・2

      Pages: 269-275

    • Data Source
      KAKENHI-PROJECT-17590121
  • [Journal Article] 生体肝移植のTDM2006

    • Author(s)
      矢野育子ほか
    • Journal Title

      TDM研究 23(2)

      Pages: 63-64

    • Data Source
      KAKENHI-PROJECT-18659157
  • [Journal Article] 薬物血中濃度モニタリングの現状と課題(5)2005

    • Author(s)
      矢野育子
    • Journal Title

      Drug Metab.Pharmacokinet. 20・5

      Pages: 25-28

    • Data Source
      KAKENHI-PROJECT-17590121
  • [Presentation] Physiologically-based pharmacokinetic modeling and simulation of fentanyl for treatment optimization in neonates.2023

    • Author(s)
      Yamamoto K, Mahdy WYB, Hashimoto M, Hasegawa M, Nakasone R, Fujioka K, Itohara K, Kitahiro Y, Omura T, Yano I
    • Organizer
      The 21st International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT 2023)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] 抗てんかん薬の薬物動態と投与設計up-to-date2023

    • Author(s)
      矢野育子
    • Organizer
      第6回 Kinki Epilepsy Summit-てんかんの新知見とパラダイムシフト-
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] 免疫チェックポイント阻害薬投与患者の好中球リンパ球比による層別化とプロトンポンプ阻害薬の併用による生命予後への影響2023

    • Author(s)
      堀智貴,山本和宏,伊藤武文,生島繁樹,大村友博,矢野育子
    • Organizer
      日本臨床腫瘍薬学会学術大会2023
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] 非小細胞肺がん患者におけるオシメルチニブの有害事象に関する薬理遺伝学的解析2023

    • Author(s)
      丹田雅明,山本和宏,堀智貴,西口大生,八木美樹,清水倫子,小西徹,尾崎智規,吉岡奈津恵,立原素子,伊藤武文,生島繁樹,大村友博,矢野育子
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] ブレクスピプラゾール,クエチアピンおよびリスペリドンを服用中の妊婦とその児における薬物動態の評価2023

    • Author(s)
      小西徹,北廣優実,藤原尚子,山本和宏,糸原光太郎,大村友博,矢野育子
    • Organizer
      第45回日本病院薬剤師会近畿学術大会
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] Physiologically-based pharmacokinetic model analysis of risperidone and its active metabolite paliperidone in a pregnant woman and her neonate2023

    • Author(s)
      Ikuko Yano
    • Organizer
      第97回日本薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] 成人肝移植患者におけるエベロリムスの母集団薬物動態解析および小児肝移植患者への外挿2022

    • Author(s)
      糸原光太郎,矢野育子,中川俊作,杉本充弘,平井真智子,米澤淳,平大樹,伊藤孝司,秦浩一郎,波多野悦朗,寺田智祐,松原和夫
    • Organizer
      第43回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] Effects of pregnancy and renal ontogeny on risperidone/paliperidone pharmacokinetics predicted by physiologically based pharmacokinetic model2022

    • Author(s)
      Yamamoto K, Mahdy WYB, Ito T, Fujiwara N, Fujioka K, Horai T, Otsuka I, Imafuku H, Omura T, Iijima K, Yano I
    • Organizer
      The 20th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] Effects of long-term multiple immunosuppressants on everolimus pharmacokinetics in patients after renal transplantation2022

    • Author(s)
      Tomoyuki Sakaue, Kazuhiro Yamamoto, Takahito Endo, Takeshi Ishimura, Masato Fujisawa, Tomohiro Omura, Ikuko Yano
    • Organizer
      第32回医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] クリニカルファーマコメトリクス概論:個別化投与設計の変遷,2022

    • Author(s)
      矢野育子
    • Organizer
      日本医療薬学会 第86回医療薬学公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06697
  • [Presentation] 新生児におけるバンコマイシン血中濃度の生理学的薬物動態モデルを用いた個別シミュレーションとGFR推算法の影響2021

    • Author(s)
      山本和宏,Walaa Mahdy,石井順子,橋本真梨,阪上倫行,藤原尚子,藤岡一路, 飯島一誠,大村友博,矢野育子
    • Organizer
      第37回日本TDM学会・学術大会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Development of a Physiologically Based Pharmacokinetic Model of Fentanyl for Preventing Central Toxicity in Neonate Patients on Respiratory Support2021

    • Author(s)
      Walaa Yousef Bassyouni Mahdy1, Kazuhiro Yamamoto1, Risa Joji1, Mari HashiWalaa Yousef Bassyouni Mahdy, Kazuhiro Yamamoto, Risa Joji, Mari Hashimoto, Ruka Nakasone, Kazumichi Fujioka, Tomohiro Omura, Ikuko Yano
    • Organizer
      IATDMCT2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 腎癌患者におけるスニチニブの薬物動態モデル解析2021

    • Author(s)
      伊藤雄大、山本和宏、大村友博、矢野育子
    • Organizer
      第31回日本医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Clinical significance of therapeutic drug monitoring of sunitinib in patients with metastatic renal cell carcinoma treated with a 2-week-on and 1-week-off schedule2021

    • Author(s)
      Takahiro Ito, Kazuhiro Yamamoto, Junya Furukawa, Kenichi Harada, Masato Fujisawa, Tomohiro Omura, Ikuko Yano
    • Organizer
      第31回日本医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Development of Physiologically Based Pharmacokinetic Model of Risperidone and Extrapolation to Different Ethnic Groups and Special Population2021

    • Author(s)
      Walaa Mahdy, Kazuhiro Yamamoto, Tomohiro Omura, Ikuko Yano
    • Organizer
      2021 CSPS/PSJ/CC-CRS SYMPOSIUM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] ブレクスピプラゾール服用妊婦における母児血漿中濃度および母乳中濃度解析を行った1例2021

    • Author(s)
      藤原尚子,伊藤雄大,小西徹,橋本真梨,山本和宏,藤岡一路,今福仁美, 蓬莱政,青山慎介,大村友博,矢野育子
    • Organizer
      医療薬学フォーラム2021
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Association of serum fentanyl concentration and oxygen desaturation with oversedation in neonates2021

    • Author(s)
      Kazuhiro Yamamoto, Risa Joji, Mari Hashimoto, Walaa Yousef Bassyouni Mahdy, Ruka Nakasone, Kazumichi Fujioka, Tomohiro Omura, Ikuko Yano
    • Organizer
      IATDMCT2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 医薬品適正使用を目指した薬物動態研究の実践 -これまでのキャリアを振り返って-2020

    • Author(s)
      矢野育子
    • Organizer
      文部科学省科学技術人材育成費補助事業「ダイバーシティ研究環境実現イニシアティブ(連携型)清流の国輝くギフジョ支援プロジェクト」 「キャリパス支援講演会」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Physiologically-based pharmacokinetic modeling and simulation of serum risperidone and paliperidone concentrations in pregnant woman taking risperidone and in her baby2020

    • Author(s)
      Walaa Mahdy, Kazuhiro Yamamoto, Takahiro Ito, Kazumichi Fujioka, Tadasu Horai, Ikuo Otsuka, Hitomi Imafuku, Tomohiro Omura, Kazumoto Iijima, Ikuko Yano
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 腎細胞癌患者を対象とした2週投与1週休薬スケジュール下におけるスニチニブ至適血中濃度に関する検討2020

    • Author(s)
      伊藤雄大,山本和宏,北村匠,古川順也,原田健一,藤澤正人,大村友博,矢野育子
    • Organizer
      第41回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 腎移植患者におけるタクロリムスPBPKモデル構築と肝移植患者の薬物動態との比較2020

    • Author(s)
      糸原光太郎、矢野育子、中川俊作、米澤淳、中川貴之、今井哲司、小川修、小林恭、坂井薫、松原和夫
    • Organizer
      第41回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 腎移植後にスニチニブ治療を開始した腎癌患者におけるタクロリムス・エベロリムスの薬物動態モデル解析2020

    • Author(s)
      伊藤雄大,山本和宏,小川悟史,古川順也,原田健一,藤澤正人,大村友博,矢野育子
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 薬物動態モデル解析の変遷と薬剤師として想うこと2020

    • Author(s)
      矢野育子
    • Organizer
      第23回千葉TDMセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Pharmacokinetic assessment for a case of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model2019

    • Author(s)
      Kazuhiro Yamamoto, Sachiyo Fukushima, Yui Mishima, Mari Hashimoto, Kei Yamakawa, Kazumichi Fujioka, Kazumoto Iijima, Ikuko Yano
    • Organizer
      The 17th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] 医薬品適正使用のためのクリニカルファーマコメトリクス2019

    • Author(s)
      矢野育子
    • Organizer
      日本薬学会第139年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 血清クレアチニン低値の患者におけるバンコマイシン母集団薬物動態解析2019

    • Author(s)
      大野由花,阪上倫行,山本和宏,平大樹,上島智,角本幹夫,矢野育子
    • Organizer
      医療薬学フォーラム2019
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Population pharmacokinetic modeling of everolimus in renal transplant patients with multiple immunosuppressive therapy2019

    • Author(s)
      Tomoyuki Sakaue, Kazuhiro Yamamoto, Takahito Endo, Takeshi Ishimura, Tomohiro Omura, Ikuko Yano
    • Organizer
      日本薬物動態学会第34回年会
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Use of PBPK model simulator for the individualized therapy2019

    • Author(s)
      Ikuko Yano
    • Organizer
      The 17th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07219
  • [Presentation] Drug metabolism in pediatric populations2018

    • Author(s)
      Yano I
    • Organizer
      2018 International Meeting on 22nd MDO and 33rd JSSX
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Physiologically based pharmacokinetic model for tacrolimus in living-donor liver transplantation considering liver regeneration and CYP3A5 genotype2018

    • Author(s)
      Itohara K, Yano I, Tsuzuki T, Uesugi M, Nakagawa S, Yonezawa A, Okajima H, Kaido T, Uemoto S, Matsubara K
    • Organizer
      2018 International Meeting on 22nd MDO and 33rd JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 薬物動態学(PK)の観点から見る免疫抑制剤2018

    • Author(s)
      矢野育子
    • Organizer
      日本臓器保存生物医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Influence of CYP2C19 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in the combination therapy with lansoprazole in Japanese renal transplant recipients2018

    • Author(s)
      Yamamoto K, Iida M, Yoshida A, to T, Yokoyama N, Ishimura T, Fujisawa M, Yano I
    • Organizer
      IATDMCT2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] リスペリドンによる錐体外路症状とCYP2D6遺伝子多型の関連2018

    • Author(s)
      伊藤雄大,山本和宏,大澤史宜,大塚郁夫,菱本明豊, 曽良一郎,平井みどり,矢野育子
    • Organizer
      日本医療薬学会第2回フレッシャーズ・カンファランス
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] アルプラゾラム服用妊婦から出生した児の薬物血中濃度測定を行った一症例2018

    • Author(s)
      三島 唯、山本和宏、橋本真梨、福嶋祥代、藤岡一路、矢野育子
    • Organizer
      第35回日本TDM学会・学術大会
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Development of a pediatric dosing regimen of trichlofos and chloral hydrate based on population pharmacokinetics and pharmacodynamics in pediatric intensive care patients2018

    • Author(s)
      Inoue M, Itohara K, Sato H, Kato Y, Ishii S, Yano I, Yonezawa Y, Matsubara K, Ito Y, Kamijima M, Nasu T, Yamagishi M, Sawa T, Hashimoto S
    • Organizer
      9 th Congress of World Federation of Pediatric Intensive and Critical Care Societies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Up-to-date 抗てんかん薬のTDM2018

    • Author(s)
      矢野育子
    • Organizer
      第68回日本薬学会近畿支部総会・大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Association of Pharmacokinetic and Pharmacodynamic Markers of Mycophenolic Acid and Clinical Outcomes in Cord Blood Transplant Patients2018

    • Author(s)
      Yano I, Yoshimura K, Yamamoto T, Kawanishi M, Isomoto Y, Yonezawa A, Kondo T, Takaori-Kondo A, Matsubara K
    • Organizer
      IATDMCT2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Population pharmacokinetics and pharmacodynamics of trichloroethanol in pediatric patients2017

    • Author(s)
      Itohara K, Inoue M, Yano I, Sato H, Kato Y, Ishii S, Yonezawa A, Ito Y, Kamijima M, Sawa T, Hashimoto S, Matsubara K
    • Organizer
      JSSX2017
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] CYP2C19 polymorphism affects the efficacy but not drowsiness in the low dose clobazam therapy2017

    • Author(s)
      Hashi S, Yano I, Shibata M, Matsumoto R, Ikeda A, Yonezawa A, Takahashi R, Matsubara K
    • Organizer
      15th IATDMCT
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 実臨床データを用いたファーマコメトリクスによる個体間変動予測2017

    • Author(s)
      矢野育子
    • Organizer
      第38回日本臨床薬理学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 生体肝移植術後のタクロリムス静脈内投与から経口投与への切り替え換算量に関する検討2017

    • Author(s)
      飯田真之,山本和宏,伊藤雄大,大澤史宜,西岡達也,久米学,槇本博雄,横山直己,石村武志,藤澤正人、矢野育子
    • Organizer
      第34回日本TDM学会・学術大会
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 小児におけるトリクロロエタノールの薬物動態・薬力学の発達・成長に伴う変化の解析2017

    • Author(s)
      井上美帆,糸原光太郎,佐藤博貴,加藤祐子,石井祥代,伊藤由起,中平有紀,那須民江,上島通浩,矢野育子,松原和夫,佐和貞治,橋本悟
    • Organizer
      第38回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 生理学的薬物動態モデルを用いた生体肝移植患者におけるタクロリムスのモデリング&シミュレーション2017

    • Author(s)
      矢野育子
    • Organizer
      第11回日本薬物動態学会ショートコース
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Population pharmacokinetic modeling and simulation of topiramate using the routinely monitored data for the individualized dosage adjustment2017

    • Author(s)
      Takeuchi M, Yano I, Ito S, Sugimoto M, Yamamoto S, Yonezawa A, Ikeda A, Matsubara K
    • Organizer
      15th IATDMCT
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] TDM for a new class of anti-epileptic drugs2017

    • Author(s)
      Yano I
    • Organizer
      15th IATDMCT
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] ファーマメトリクスに基づくタクロリムス投与個別適正化の実践2016

    • Author(s)
      都築徹教,矢野育子,松原和夫
    • Organizer
      第26回日本医療薬学会年会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2016-09-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 生体肝移植術後のタクロリムス静脈内投与から経口投与への切り替え換算量に関する検討2016

    • Author(s)
      都築徹教、矢野育子,中川俊作,杉本充弘,佐藤裕紀,津田真弘,上杉美和,岡島英明,海道利実,上本伸二,松原和夫
    • Organizer
      第33回日本TDM学会・学術大会
    • Place of Presentation
      栃木県総合文化センター(栃木県・宇都宮市)
    • Year and Date
      2016-05-28
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 生体肝移植術後における1日1回製剤のタクロリムス薬物動態と薬効2016

    • Author(s)
      岩崎真実,矢野育子,端 幸代,山本由貴,杉本充弘,福土将秀,増田智先,中川俊作,米澤淳,海道利実,上本伸二,松原和夫
    • Organizer
      第37回日本臨床薬理学会
    • Place of Presentation
      米子コンベンションセンター(鳥取県・米子市)
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 臍帯血移植患者におけるミコフェノール酸血中濃度と急性GVHD発症との関連2016

    • Author(s)
      吉村和晃,矢野育子,山本 崇,川西美咲,礒本唯,米澤 淳,近藤忠一,高折晃史,松原和夫
    • Organizer
      第37回日本臨床薬理学会
    • Place of Presentation
      米子コンベンションセンター(鳥取県・米子市)
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 実臨床データを用いた新規抗てんかん薬のファーマコメトリクス2016

    • Author(s)
      矢野育子
    • Organizer
      医療薬学フォーラム2016
    • Place of Presentation
      びわ湖ホール(滋賀県・大津市)
    • Year and Date
      2016-06-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] Physiologically-based pharmacokinetic modeling and simulation of tacrolimus in living-donor liver transplantation: Effects of liver regeneration and CYP3A5 genotype2016

    • Author(s)
      Itohara K, Yano I, Tsuzuki T, Nakagawa S, Yonezawa A, Okajima H, Kaido T, Uemoto S, Matsubara K
    • Organizer
      日本薬物動態学会第31回年会
    • Place of Presentation
      キッセイ文化ホール(長野県・松本市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K08400
  • [Presentation] 造血幹細胞移植患者におけるミコフェノール酸の母集団PK-PD解析2015

    • Author(s)
      吉村和晃、矢野育子、川西美咲、山本 崇、 兼吉真千子、米澤 淳、近藤忠一、高折晃史、松原和夫
    • Organizer
      第 36 回日本臨床薬理学会学術総会
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2015-12-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] LC-MS/MSを用いたTDM2015

    • Author(s)
      矢野育子
    • Organizer
      第29回北海道TDM研究会研究発表会
    • Place of Presentation
      北海道薬科大学サテライトキャンパス、札幌
    • Year and Date
      2015-12-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] 免疫抑制剤のPK-PD解析と個別化投与設計2015

    • Author(s)
      矢野育子
    • Organizer
      医療薬学フォーラム2015/第23回クリニカルファーマシーシンポジウム
    • Place of Presentation
      名古屋国際会議場、名古屋
    • Year and Date
      2015-07-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] 移植患者におけるミコフェノール酸のAUCと臨床効果に関する検討2013

    • Author(s)
      橋本恵美奈、増田智先、端 幸代、高橋 有、西岡由貴、新迫恵子、松田裕也、河合知喜、矢野育子、松原和夫
    • Organizer
      医療薬学フォーラム2013
    • Place of Presentation
      もてなしドーム地下広場、金沢
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] LC-MS/MSを用いたミコフェノール酸血中濃度及び薬効モニタリング法の構築2013

    • Author(s)
      川西 美咲、吉村和晃、山本 崇、端 幸代、増田智先、松原和夫、矢野育子
    • Organizer
      医療薬学フォーラム2013
    • Place of Presentation
      もてなしドーム地下広場、金沢
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] Clinical significance of blood concentration monitoring of everolimus in Japanese patients with Renal Cell Carcinoma2013

    • Author(s)
      Tanaka A, Shinsako K, Sato S, Fukudo M, Masuda S, Matsubara K, Kamba T, Yamasaki T, Ogawa O, Yano I
    • Organizer
      28th JSSX annual Meeting
    • Place of Presentation
      タワーホール船堀、東京
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] 抗てんかん薬の脳移行に及ぼす薬物排出トランスポータの影響2011

    • Author(s)
      矢野育子、中西晴香, ほか
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸学院大学(兵庫県)
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] 難治性てんかん患者のクロバザム治療におけるCYP2C19遺伝子多型の寄与2011

    • Author(s)
      柴田茉衣、端幸代、増田智先、桂敏也、池田昭夫、松本理器、高橋良輔、矢野育子
    • Organizer
      第32回日本臨床薬理学会年会
    • Place of Presentation
      アクトシティ浜松(静岡県)
    • Year and Date
      2011-12-01
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] 抗てんかん薬の脳移行に及ぼす薬物排出トランスポータの影響2011

    • Author(s)
      中西晴香、柴田茉衣、桂敏也、矢野育子
    • Organizer
      第61回日本薬学会近畿支部総会
    • Place of Presentation
      大会、神戸学院大学(兵庫県)
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] Significance of trough monitoring of tacrolimus blood concentration and calcineurin activity in living-donor liver transplant patients2011

    • Author(s)
      Yano I, Masuda S, Egawa H, Sugimoto M, Fukudo M, Yoshida Y, Yasuda Y, Kaido T, Uemoto S, Inui K
    • Organizer
      12th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology
    • Place of Presentation
      Stuttgart,(Germany)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] 新規抗てんかん薬ラモトリギンの血中濃度測定と相互作用に関する検討2011

    • Author(s)
      端幸代、矢野育子、増田智先、柴田茉衣、中西晴香、桂敏也、松本理器、池田昭夫、高橋良輔
    • Organizer
      第28回日本TDM学会・学術大会
    • Place of Presentation
      広島国際会議場(広島県)
    • Year and Date
      2011-06-18
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] Population pharmacokinetics and pharmacogenetics of clobazam and its active metabolite in Japanese adults with refractory epilepsy.2010

    • Author(s)
      Yano, I., et al.
    • Organizer
      World Pharma 2010
    • Place of Presentation
      Bella Center(Copenhagen)
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] UPLC/MS/MS法を用いた抗てんかん薬一斉測定法の構築2010

    • Author(s)
      柴田茉衣、矢野育子、安田幸代、増田智先、桂敏也
    • Organizer
      第31回日本臨床薬理学会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] Population pharmacokinetics and pharmacogenetics of clobazam and its active metabolite in Japanese adults with refractory epilepsy2010

    • Author(s)
      Yano I, Shibata M, Yasuda S, Yokomasu A, Hosohata K, Masuda S, Ikeda A, Takahashi R, Inui K
    • Organizer
      WORLDPHARMA
    • Place of Presentation
      Copenhagen,(Dan mark)
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] 成人難治性てんかん患者における低用量クロバザムの体内動態と臨床効果に与えるCYP2C19およびCYP3A5遺伝子多型の影響2009

    • Author(s)
      安田幸代、矢野育子、細畑圭子、増田智先、池田昭夫、高橋良輔、乾賢一
    • Organizer
      第26回日本TDM学会・学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県)
    • Year and Date
      2009-06-14
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] 抗てんかん薬クロバザム及び活性代謝物N-デスメチルクロバザム体内動態の母集団解析とファーマコゲノミクス2009

    • Author(s)
      柴田茉衣, 矢野育子, 安田幸代, 横増晃, 細畑圭子, 増田智先, 池田昭夫, 高橋良輔, 乾賢一
    • Organizer
      第30回日本臨床薬理学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21590156
  • [Presentation] シンポジウム6「薬学教育において実務家教員が果たすべき役割」 : 実務家教員の現状(アンケート調査結果より)2008

    • Author(s)
      矢野育子
    • Organizer
      第18回日本医療薬学会年会
    • Place of Presentation
      北海道
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] シクロスポリンのTDMと腎障害の軽減2008

    • Author(s)
      矢野育子, 乾賢一
    • Organizer
      第51回日本腎臓学会学術総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] 癌化学療法における骨髄抑制作用の経時的変化に関する速度論的解析2008

    • Author(s)
      矢野義孝, 他
    • Organizer
      第29回日本臨床薬理学会
    • Place of Presentation
      東京
    • Year and Date
      2008-12-05
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] カルシニューリン阻害剤のPK/PD2008

    • Author(s)
      矢野育子, 他
    • Organizer
      第11回宝ケ池セミナー
    • Place of Presentation
      京都
    • Year and Date
      2008-11-08
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] ワークショップ2「薬物と腎障害」 : シクロスポリンのTDMと腎障害の軽減2008

    • Author(s)
      矢野育子, 他
    • Organizer
      第51回日本腎臓学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] カルシニューリン阻害剤の体内動態と薬効の速度論的解析に基づく個別化投与設計法2008

    • Author(s)
      矢野育子
    • Organizer
      第一回臨床薬理研究振興財団研究報告会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-13
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] シンポジウム : PK-PDを見直す-臨床に直結する考え方は? : 薬物動態特性に基づく抗菌薬の適正使用2007

    • Author(s)
      矢野育子, 他
    • Organizer
      第50回日本感染症学会中日本地方会学術集会. 第55回日本化学療法学会西日本支部総会同時開催学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] 臓器移植に生かす免疫抑制剤のPK/PD2007

    • Author(s)
      矢野育子、乾 賢一
    • Organizer
      第17回日本医療薬学会年会, シンポジウム29-S4
    • Place of Presentation
      群馬
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] シンポジウム29-S4一歩進んだ「がん薬物業務」 : 臓器移植に生かす免疫抑制剤のPK/PD2007

    • Author(s)
      矢野育子, 他
    • Organizer
      第17回日本医療薬学会年会
    • Place of Presentation
      群馬
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] 抗てんかん薬クロバザムおよび活性代謝物デスメチルクロバザムの体内動態解析2007

    • Author(s)
      矢野育子, 他
    • Organizer
      第28回日本臨床薬理学会
    • Place of Presentation
      栃木
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-19590141
  • [Presentation] The role of pharmacists in organ transplantation

    • Author(s)
      Yano I
    • Organizer
      13th Congress of the Asian Society of Transplantation (CAST2013)
    • Place of Presentation
      京都国際会館、京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] Impact of p-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs.

    • Author(s)
      Yano I, Nakanishi H, Yonezawa A, Matsubara K
    • Organizer
      13th International congress of Therapeutic Drug Monitoring & Clinical Toxicology
    • Place of Presentation
      Grand America Hotel, Salt Lake City, USA
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] 無アルブミン血症ラットにおけるミコフェノール酸の薬物動態と薬効

    • Author(s)
      吉村和晃、矢野育子、川西美咲、松原和夫
    • Organizer
      医療薬学フォーラム2014
    • Place of Presentation
      ビッグサイトTFTホール、東京
    • Year and Date
      2014-06-28 – 2014-06-29
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] 小児医薬品評価におけるModeling and Simulationの活用について

    • Author(s)
      矢野育子
    • Organizer
      第34回日本臨床薬理学会学術総会
    • Place of Presentation
      東京フォーラム、東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] Effect of protein binding on pharmacokinetics and pharmacodynamics of mycophenolic acid using a population-modeling approach

    • Author(s)
      Yoshimura K, Yano I, Kawanishi M, Matsubara K
    • Organizer
      29th JSSX/19th NA ISSX Joint Meeting
    • Place of Presentation
      SanFrancisco, USA
    • Year and Date
      2014-10-19 – 2014-10-23
    • Data Source
      KAKENHI-PROJECT-25460210
  • [Presentation] “From Bench to Bedside”-Application of Science to Clinical Practice

    • Author(s)
      Yano I
    • Organizer
      6th Asian Association of Schools of Pharmacy Conference
    • Place of Presentation
      National Singapore University, Singapore
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460210
  • 1.  MASUDA Satohiro (90303825)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 11 results
  • 2.  INUI Ken-ichi (70034030)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HASHIMOTO Yukiya (90228429)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SAITO Hideyuki (40225727)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  OKUDA Masahiro (70252426)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  KATSURA Toshiga (10283615)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  FUKUDO Masahide (60437233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 8.  山本 和宏 (30610349)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 24 results
  • 9.  糸原 光太郎 (00870445)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 10.  ISHIGURO Hiroshi (20422925)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 11.  YANAGIHARA Kazuhiro (70332731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  IKEDA Akio (90212761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 13.  YAMASHITA Fumiyoshi (30243041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  AMANO Akira (60252491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TETSUYA Aiba (00231754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TERADA Tomohiro (10324641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MOTOHASHI Hideyuki (30359822)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  INOUE Miho
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 19.  HISHIMOTO Akitoyo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  松原 和夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 21.  曽良 一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  赤池 昭紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  中川 俊作
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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