MATSUI Minoru 松井稔

Researcher Number	50282611
Other IDs
Affiliation (based on the past Project Information) *help	2007: Chiba Institute of Science, Faculty of Pharmacy, Associate Professor 2006: 東京大学, 医科学研究所, 助教 2003 – 2006: 東京大学, 医科学研究所, 助手 2001 – 2002: 東京大学, 医科学研究所・基礎医科学部門, 助手 2000: 東京大学, 大学院・薬学研究科, 助手 1997 – 2000: 東京大学, 大学院・薬学系研究科, 助手
Review Section/Research Field	Principal Investigator General pharmacology Except Principal Investigator Anesthesiology/Resuscitation studies / Urology / 遺伝 / Pathological medical chemistry / Obstetrics and gynecology / Otorhinolaryngology / General pharmacology
Keywords	Principal Investigator アセチルコリン / ノックアウトマウス / ムスカリン性受容体 / 副交感神経 / acetylcholine / knockout mice / muscarinic receptor / parasympathetic nervous system Except Principal Investigator APC / アフリカツメガエル卵母細胞発現系 … More / 吸入麻酔薬 / ムスカリン受容体 / ノックアウトマウス / アセチルコリン / マウス / mouse / Cdx-2 / Cre-loxP / calcium binding protein D-9K / アフリカツメガエル卵母細胞系 / 麻酔薬 / Pain mechanism / 家族性大腸ポリポ-シス / ポリプ / 低脂肪高線維食 / 高脂肪低線維食 / イニシエーション / エンフルレン / イソフルラン / トラマドール / 痙攣 / 5HT_<2C>受容体 / アフリカツメガエル卵母細胞 / トラマドール代謝産物M1 / 燐酸化酵素 / エンフルラン / 静脈麻酔薬 / プロテインキナーゼC / M3 / 排尿障害 / ムスカリン / 排尿動熊 / プロスタグランジン / 排尿動態 / 染色体マッピング / 精巣 / 大腸癌 / リンケージ・マッピング / 大腸がん / 精巣特異的遺伝子 / chromosomal mapping / testis / colon cancer / linkage mapping / TGF-β / Smad4 / Dpc4 / β-catenin / β-cutenin / Apc遺伝子 / COX2 / Dpc4遺伝子 / 悪性化進展 / TGF-B / Smad 4 / beta-catenin / 子宮内膜 / 着床 / calcium bindidng protein D-9K / トランスジェニックマウス / 子宮 / 妊娠 / 脱落膜 / uterus / transgenic mouse / implantation / サブタイプ / パッチクランプ / ラセン神経節 / 前庭神経節 / 単離細胞 / 聴性脳幹反応(ABR) / 内耳単離細胞 / muscarinic receptor / subtype / knock-out mice / patch clamp / spiral ganglion / vestibular ganglion / dissociated cells / 疼痛 / イオンチャネル / G蛋白共役型受容体 / 脊髄後根神経節 / アルファキサロン / 鎮痛作用機序 / イオンチャンネル / サブスタンスP受容体 / 抗侵害作用 / 鎮痛薬 / パッチクランプ法 / エタノール / pain / Ion channel / G protein Coupled Receptor / Volatile Anesthetics / Dorsal root ganglia / Xenopus oocytes / Alohaxalone / 疼痛メカニズム / G蛋白共役型受容体(GPCR) / 脊髄後根神経節(Dorsal Root Ganglia, DRG)細胞 / メタボトロピックグルタミン酸受容体(mGluR) / デクスメデトミジン / 細胞内リン酸化酵素 / G蛋白結合受容体(GPCR) / 脊髄後根神経節(DRG)細胞 / 脊髄後根神経節(Dorsal Root Gnglia, DRG)細胞 / メタボトロピックグルタミン酸受容体(cGluR) / G protein couples receptors / Dorsal root ganglia cells / Metabotropic glutamte receptors / Anesthetics / Xenopus oocytes expression systems / Dexmedetomidine / Phosphorylation / 薬理学 / 薬学 / 神経科学 / 脳・神経 / 生体分子 / 受容体 / 膜胱括約筋 / ムスカリン受容体の弛緩機構 / Pharmacology / Pharmaceutical Sciences / Neuroscience / Brain and Neuron / Bioactive molecule / Acetylcholine / Receptor Less

ムスカリン受容体ノックアウトマウスの排尿障害とその代謝機能の分子生物学的解析
- Principal Investigator
  
  水谷陽一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Kyoto Prefectural University of Medicine
Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.Principal Investigator
- Principal Investigator
  
  FUJII Takeshi, 松井稔
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Doshisha Women's College of Liberal Arts
  The University of Tokyo
The study of the pain mechanisms using rat dorsal root ganglia
- Principal Investigator
  
  MINAMI Koucihiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Jichi Medical University
  University of Occupational and Environmental Health, Japan
The role of the metabotropic gultamete receptor in the pain mechanism
- Principal Investigator
  
  SHIGA Yousuke
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
麻酔薬、鎮痛薬の痙攣誘発作用におけるセロトニン受容体のはたす役割解明
- Principal Investigator
  
  相原啓二
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
On the role of subtypes of muscarinic receptors in the inner ear
- Principal Investigator
  
  ITO Ken
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Development of the animal model with controllable fertility through targeting implantation
- Principal Investigator
  
  YOSHIMURA Yasunori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Analysis of muscarinic receptor function using knockout micePrincipal Investigator
- Principal Investigator
  
  MATSUI Minoru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Research of the polyp formation in the intestine using Knock-out mouse
- Principal Investigator
  
  TAKATO M. Makoto
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
ノックアウト・マウスを用いた腸ポリプ症の化学療法の研究
- Principal Investigator
  
  TAKETO M.Makoto
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Mapping of Novel Mouse and Human Genes
- Principal Investigator
  
  TAKETO M.Makoto
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  遺伝
- Research Institution
  The University of Tokyo

All 2007 2006 2005

All Journal Article

[Journal Article] Tonic enhancement of endocannabinoid-mediated retrograde suppression of inhibition by cholinergic interneuron activity in the striatum.2007
- Author(s)
  Narushima M, Uchigashima M, Fukaya M, Matsui M, Manabe T, Hashimoto K, Watanabe M, Kano M
- Journal Title
  
  J Neurosci 27・3
  
  Pages: 496-506
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Up-regulated PAR-2-mediated salivary secretion in mice deficient in muscarinic acetylcholine receptor subtypes.2007
- Author(s)
  Nishiyama T, Nakamura T, Obara K, Inoue H, Mishima K, Matsumoto N, Matsui M, Manabe T, Mikoshiba K, Saito I
- Journal Title
  
  J Pharmacol Exp Ther 320・2
  
  Pages: 516-524
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Differential coupling of muscarinic M1, M2, and M3 receptors to phosphoinositide hydrolysis in urinary bladder and longitudinal muscle of the ileum of the mouse.2006
- Author(s)
  Tran JA, Matsui M, Ehlert FJ
- Journal Title
  
  J Pharmacol Exp Ther 318・2
  
  Pages: 649-656
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Aging and Progression of Hearing Loss in Mice Locking Muscarinic Acetylcholine Recepeor Subtype32005
- Author(s)
  Ken Ito.Shinichi Iwasaki, Minoru Matsui
- Journal Title
  
  Abstvaets of the Annwal Research Meeting, Association for Research in Otolanyngology 28
  
  Pages: 148-148
- Data Source
  KAKENHI-PROJECT-15591798
[Journal Article] Aging and progression of hearing loss in mice lacking muscarinic acetylcholine receptor sybtype 32005
- Author(s)
  Ito K, Iwasaki S, Matsui M
- Journal Title
  
  Abstracts of the Annual Research Meeting, Assocication for Research in Otolaryngology 28
  
  Pages: 148-148
- Data Source
  KAKENHI-PROJECT-15591798
[Journal Article] Aging and progression of hearing loss in mice lacking muscarinic acetylcholine receptor sybtype 32005
- Author(s)
  Ito K, Iwasaki S, Matsui M
- Journal Title
  
  Abstracts of the Annual Research Meeting, Association for Research in Otolaryngology 28
  
  Pages: 148-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591798

1. TAKETO M.Makoto (70281714)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. MINAMI Koucihiro (70279347)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. UEZONO Yasuhito (20213340)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SHIRAISHI Munehiro (40389458)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SASAKI Nobuya (20302614)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. FUJII Takeshi (80255380)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKAKU Kazuaki (90313121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIMURA Yasunori (10129736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMIZU Aki (60306826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MARUYAMA Tetsuo (10209702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Ken (50251286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. IWASAKI Shinichi (10359606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. UETA Yoichi (10232745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIGA Yousuke (10399199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKATORI Yuki (90411090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMADA Shizuo (80106434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKEUCHI Tadayoshi (00171611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KAWASHIMA Koichiro (70095008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 相原啓二 (70258622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 佐多竹良 (60128030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 水谷陽一 (10243031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 河内明宏 (90240952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 三木恒治 (10243239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 牛嶋壮 (10398373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 山本百合恵 (00286543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 酒井のぞみ (60276326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 堀下貴文 (40369070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. セルディンマイケル

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. SELDIN F.Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 岩崎真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

MATSUI Minoru 松井 稔

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Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.Principal Investigator

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Analysis of muscarinic receptor function using knockout micePrincipal Investigator

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[Journal Article] Tonic enhancement of endocannabinoid-mediated retrograde suppression of inhibition by cholinergic interneuron activity in the striatum.2007

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[Journal Article] Up-regulated PAR-2-mediated salivary secretion in mice deficient in muscarinic acetylcholine receptor subtypes.2007

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Data Source

[Journal Article] Differential coupling of muscarinic M1, M2, and M3 receptors to phosphoinositide hydrolysis in urinary bladder and longitudinal muscle of the ileum of the mouse.2006

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Data Source

[Journal Article] Aging and Progression of Hearing Loss in Mice Locking Muscarinic Acetylcholine Recepeor Subtype32005

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[Journal Article] Aging and progression of hearing loss in mice lacking muscarinic acetylcholine receptor sybtype 32005

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MATSUI Minoru 松井稔