) 竹内正吉

… Alternative Names

Researcher Number	00171611
Other IDs
Affiliation (Current) *help	2018 : 大阪府立大学, 生命環境科学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 : 大阪府立大学, 生命環境科学研究科, 教授 2015 : 大阪府立大学, 生命環境科学研究科(系), 教授 2011 : 大阪府立大学, 生命環境科学研究科・獣医学専攻, 教授 2009 – 2011 : 大阪府立大学, 生命環境科学研究科, 教授 2006 – 2007 : 大阪府立大学, 生命環境科学研究科, 教授 2003 – 2004 : 大阪府立大学, 農学生命科学研究科, 助教授 1995 – 1996 : 大阪府立大学, 農学部, 助教授
Review Section/Research Field	Principal Investigator Basic veterinary science/Basic zootechnical science / Basic veterinary science/Basic zootechnical science / Veterinary medical science Except Principal Investigator Basic veterinary science/Basic zootechnical science / General pharmacology / Applied veterinary science
Keywords	Principal Investigator cyclic AMP / Protein Kinase C / アセチルコリン放出 / Ca^<2+>-independent fusion / アセチルコリン遊離 / ACh release and autoreceptors / Aging / Nicotinic receptors / distension-induced response / M_2とM_4受容体subtype … More Except Principal Investigator 新規治療薬開発 / 神経伝達機構 / ポリグルタミン病 / 消化管 / Acetylcholine / ムスカリン受容体の弛緩機構 / 生体分子 / fibroblast様細胞 / アセチルコリン / 受容体 / interstitial cells of Cajal / Ca^<2+>-activated K^+ channel / 膜胱括約筋 / イオンチャネル / 歩調取り細胞 / 消化管運動 / てんかん / Bioactive molecule / ボツリヌス菌 / Neuroscience / apamin / 薬学 / Brain and Neuron / 脳・神経 / カハールの介在細胞 / ペースメーカー細胞 / 神経科学 / SK channel / パーキンソン病 / 疾病予防・制御 / 薬理学 / Pharmacology / ボツリヌス毒素 / Pharmaceutical Sciences / Receptor / C3酵素 / 脳神経疾患 Less

A neurotrophic role of extracellular poly (ADP-ribose) in neurological sdisordersPrincipal Investigator
- Principal Investigator
  
  Takeuchi Tadayoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Preclinical study for the therapeutic application of botulinum neurotoxin to intractable brain disorders.
- Principal Investigator
  
  KOZAKI Syunji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.
- Principal Investigator
  
  FUJII Takeshi, MATSUI Minoru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Doshisha Women's College of Liberal Arts
  The University of Tokyo
Interaction among the modulating factors for regulating the motility of gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tadayoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University
Age-related changes of motility-regulating factors in the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Tadayoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University
消化管カハール細胞での自発活動発現機序に関する生理学及び分子学的研究
- Principal Investigator
  
  藤田秋一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University
Physiological Signiticance of Phospholipase A_2 activation in neuronal activity.Principal Investigator
- Principal Investigator
  
  TAKEUCHI Tadayoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Pretecture University

All 2017 2016 2012 2011 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivo.2017
- Author(s)
  Nakajima H, Itakura M, Sato K, Nakamura S, Azuma YT, Takeuchi T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 484 Pages : 385-389
- DOI
  10.1016/j.bbrc.2017.01.129
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05029, KAKENHI-PROJECT-15K14857
[Journal Article] A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain2012
- Author(s)
  Nakajima, H., Kubo, T., Semi, Y., Itakura, M., Kuwamura, M., Izawa, T., Azuma, YT., Takeuchi, T.
- Journal Title
  
  J. Biotech
  
  Volume : 157 Pages : 326-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380188
[Journal Article] M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum : Findings obtained with muscarinic-receptor knockout mouse2007
- Author(s)
  Takeuchi, T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 292・1
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] A mionor role for Ca(2+)sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon2007
- Author(s)
  Takeuchi, T
- Journal Title
  
  Pflugers Arch. 454
  
  Pages : 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] M_2 and M_3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum : findings obtained using muscarinic receptor knockout mouse.2007
- Author(s)
  Takeuchi T
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol 292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] M_2 and M_3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: findings obtained using muscarinic receptor knockout mouse2007
- Author(s)
  Takeuchi, T, Tanaka, K, Nakajima, H, Matsui, M, Azuma, YT
- Journal Title
  
  Am J Physiol. Gastrointest Liver Physiol 292(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum2007
- Author(s)
  Nakajima, H, Goto, H, Azuma, YT, Fujita, A, Takeuchi, T
- Journal Title
  
  J Neurochem 103
  
  Pages : 2428-2438
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ilerm:Findings obtained with muscarinic-receptor knockout mouse2007
- Author(s)
  Takeuchi, T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 292
  
  Pages : 154-164
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] A minor role for Ca(2+)sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon2007
- Author(s)
  Takeuchi, T
- Journal Title
  
  Pflugers Arch 454
  
  Pages : 565-574
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] A minor role for Ca(2+) sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon2007
- Author(s)
  Takeuchi, T, Nakajima, H, Hata, F, Azuma, YT
- Journal Title
  
  Pflugers Arch. 454(4)
  
  Pages : 565-574
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum : Findings obtained with muscarinic-receptor knockout mice.2007
- Author(s)
  Takeuchi T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 292・1
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] M_2 and M_3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum:findings obtained using muscarinic receptor knockout mouse2007
- Author(s)
  Takeuchi T
- Journal Title
  
  American Journal of Physiology Gastrointestinal and Liver Physiology 292
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Inhibitory effects of alendronate on cholinergic responses in rat lower esophageal sphincter2006
- Author(s)
  Takeuchi, T
- Journal Title
  
  European Journal of Pharmacology 537
  
  Pages : 155-159
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] affects ascending contration depending on downstream cholinergic neurons and descending relaxation through independent pathways in mouse jejunum2006
- Author(s)
  Satoh, Y, Okishio, Y, Azuma, YT, Nakajima, H, Hata, F, Takeuchi, T, Orexin, A
- Journal Title
  
  Neuropharmacology 51
  
  Pages : 466-473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] Inhibitory effects of alendronate on cholinergic responsis in rat lower esophageal sphincter2006
- Author(s)
  Takeuchi, T
- Journal Title
  
  European Journal of Pharmacology 537・1-3
  
  Pages : 155-159
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] Inhibitory effects of alendronate on cholinergic responses in rat lower esophageal sphincter2006
- Author(s)
  Takeuchi, T, Nakamura, A, Nakajima, H, Azuma, YT, Hata, F
- Journal Title
  
  Eur J Pharmacol 537(1-3)
  
  Pages : 155-159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Journal Article] Involvement of M_2 muscarinic receptors in relaxant response of circular muscle of mouse gastric antrum.2006
- Author(s)
  Takeuchi T
- Journal Title
  
  Neurogastroenterol. Motil 18
  
  Pages : 226-233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Involvement of M_2 muscarinic receptors in relaxant response of circular muscle of mouse gastric antrum2006
- Author(s)
  Takeuchi T
- Journal Title
  
  Neurogastroenterology and Motility 18
  
  Pages : 226-233
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Roles of M_2 and M_4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum2005
- Author(s)
  Takeuchi T, Fujinami K, Goto, H, Fujita A, Taketo MM, Manabe T, Matsui M.
- Journal Title
  
  Journal of Neurophysiology (印刷中)
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Roles of M_2 and M_4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum.2005
- Author(s)
  Takeuchi T, Fujinami K, Goto H, Fujita A, Taketo MM, Manabe T, Matsui M, Hata F.
- Journal Title
  
  J Neurophysiol. 93(5)
  
  Pages : 2841-2848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum.2005
- Author(s)
  Waseda K, Takeuchi T, Ohta M, Okishio Y, Fujita A, Hata F, Takewaki T.
- Journal Title
  
  J Pharmacol Sci. 97(1)
  
  Pages : 91-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Roles of M_2 and M_4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum2005
- Author(s)
  Takeuchi T, Fujinami K, Goto, H, Fujita A, Taketo MM, Manabe T, Matsui M, Hata F
- Journal Title
  
  Journal of Neurophysiology 93(5)
  
  Pages : 2841-2848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum2005
- Author(s)
  Waseda K, Takeuchi T, Ohta M, Okishio Y, Fujita A, Hata F, Takewaki T.
- Journal Title
  
  Journal of Pharmacological Science 97(1)
  
  Pages : 91-100
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum2005
- Author(s)
  Waseda K, Takeuchi T, Ohta M, Okishio Y, Fujita A, Hata F, Takewaki T.
- Journal Title
  
  Journal of Pharmacologycal Sciences 97・1
  
  Pages : 91-100
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Roles of interstitial cells of Cajal in regulation of motility of the mouse intestine.2004
- Author(s)
  Fujita A, Okishio Y, Takeuchi T, Hata F.
- Journal Title
  
  Folia Pharmacol Jpn. 123
  
  Pages : 170-178
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Mechanisms involved in carbachol-induced Ca^<2+> sensitization of contractile elements in rat proximal and distal colon.2004
- Author(s)
  Takeuchi T, Kushida M, Hirayama N, Kitayama M, Fujita A, Hata F.
- Journal Title
  
  Br J Pharmacol. 142(4)
  
  Pages : 657-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Role of the interstitial cells distributed in the myenteric plexus in neural reflexes in the mouse ileum.2004
- Author(s)
  Fujita A, Okishio Y, Fujinami K, Nakagawa M, Takeuchi T, Takewaki T, Hata F.
- Journal Title
  
  J Pharmacol Sci. 96(4)
  
  Pages : 483-492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Essential role of the interstitial cells of cajal in nitric oxide-mediated relaxation of longitudinal muscle of the mouse ileum.2004
- Author(s)
  Takeuchi T, Fujinami K, Fujita A, Okishio Y, Takewaki T, Hata F.
- Journal Title
  
  J Pharmacol Sci. 95(1)
  
  Pages : 71-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] マウス腸管運動調節におけるカハールの介在細胞の役割2004
- Author(s)
  藤田秋一, 置塩豊, 竹内正吉, 畑文明
- Journal Title
  
  日本薬理学会誌 121(3)
  
  Pages : 170-178
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Essential role of the interstitial cells of cajal in nitric oxide-mediated relaxation of longitudinal muscle of the mouse ileum.2004
- Author(s)
  Takeuchi T, Fujinami K, Fujita A, Okishio Y, Takewaki T, Hata F.
- Journal Title
  
  Journal of Pharmacological Science 95(1)
  
  Pages : 71-80
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Role of the interstitial cells distributed in the myenteric plexus in neural reflexes in the mouse ileum2004
- Author(s)
  Fujita A, Okishio Y, Fujinami K, Nakagawa M, Takeuchi T, Takewaki T, Hata F.
- Journal Title
  
  Journal of Pharmacological Science 96(4)
  
  Pages : 483-492
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.2004
- Author(s)
  Takeuchi T, Kushida M, Hirayama N, Kitayama M, Fujita A, Hata F.
- Journal Title
  
  British Journal of Pharmacology 142(4)
  
  Pages : 657-666
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] マウス腸管運動調節におけるカハールの介在細胞の役割2004
- Author(s)
  藤田秋一, 置塩豊, 竹内正吉, 畑文明
- Journal Title
  
  日本薬理学会誌 121・3
  
  Pages : 170-178
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Essential role of the interstitial cells of cajal in nitric oxide-mediated relaxation of longitudinal muscle of the mouse ileum.2004
- Author(s)
  Takeuchi T, Fujinami K, Fujita A, Okishio Y, Takewaki T, Hata F.
- Journal Title
  
  Journal of Pharmacological Science 95・1
  
  Pages : 71-80
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Role of the interstitial cells distributed in the myenteric plexus in neural reflexes in the mouse ileum2004
- Author(s)
  Fujita A, Okishio Y, Fujinami K, Nakagawa M, Takeuchi T, Takewaki T, Hata F.
- Journal Title
  
  Journal of Pharmacologycal Sciences 96・4
  
  Pages : 483-492
- Data Source
  KAKENHI-PROJECT-15580264
[Journal Article] Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.2004
- Author(s)
  Takeuchi T, Kushida M, Hirayama N, Kitayama M, Fujita A, Hata F.
- Journal Title
  
  British Journal of Pharmacology 142・4
  
  Pages : 657-666
- Data Source
  KAKENHI-PROJECT-15580264
[Presentation] 細胞外ポリADPリボース（EC-PAR）のグリア細胞株由来神経栄養因子（GDNF）産生機構の解明2016
- Author(s)
  佐藤啓志、中嶋秀満、板倉正典、東　泰孝、竹内正吉
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  藤沢（日本大学）
- Data Source
  KAKENHI-PROJECT-15K14857
[Presentation] 細胞外ポリADPリボース(EC-PAR)のグリア細胞株由来神経栄養因子(GDNF)産生に及ぼす影響2016
- Author(s)
  佐藤啓志、中嶋秀満、板倉正典、東　泰孝、竹内正吉
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-15K14857
[Presentation] Accell siRNAの単回脳室内投与による脳内の遺伝子サイレンシング効果2011
- Author(s)
  久保岳也、中嶋秀満、瀬見優子、桑村充、井澤武史、東泰孝、竹内正吉
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-21380188
[Presentation] NANC mediators in relaxation of the mouse distal colon2007
- Author(s)
  Takeuchi, T
- Organizer
  The 144th Annual Meeting of Japanese Society of Veterinary Science
- Place of Presentation
  ebetsu
- Year and Date
  2007-09-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Presentation] Different roles of sarcoplasmic reticulum in contraction or relaxation in the rat colon smooth muscles2007
- Author(s)
  Takeuchi, T
- Organizer
  The 112th Kinki branch Meeting in Osaka, The Japanese Pharmacological Society
- Place of Presentation
  Toyonaka
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Presentation] マウス遠位結腸の弛緩に関わるNANC性メディエイター2007
- Author(s)
  竹内正吉
- Organizer
  第144回日本獣医学会学術集会
- Place of Presentation
  江別市
- Year and Date
  2007-09-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580297
[Presentation] ラット結腸平滑筋の収縮および弛緩における筋小胞体の異なる役割2007
- Author(s)
  竹内正吉
- Organizer
  第112回日本薬理学会近畿部会
- Place of Presentation
  豊中市
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580297

1. NAKAJIMA Hidemitsu (30405360)

# of Collaborated Projects : 2results

# of Collaborated Products : 5results
2. FUJII Takeshi (80255380)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. MATSUI Minoru (50282611)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
4. KOZAKI Syunji (10109895)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. MIYAKE Masami (10251175)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. KATOH Keiko (90252684)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. TAKATORI Yuki (90411090)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. YAMADA Shizuo (80106434)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. KAWASHIMA Koichiro (70095008)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 藤田秋一 (60282232)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 東泰孝 (50298816)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results

) 竹内 正吉

TAKEUCHI Tadayoshi 竹内 正吉

Research Projects

Research Products

Co-Researchers

A neurotrophic role of extracellular poly (ADP-ribose) in neurological sdisordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preclinical study for the therapeutic application of botulinum neurotoxin to intractable brain disorders.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.

Principal Investigator

Project Period (FY)

Research Category

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Interaction among the modulating factors for regulating the motility of gastrointestinal tractPrincipal Investigator

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Age-related changes of motility-regulating factors in the gastrointestinal tractPrincipal Investigator

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消化管カハール細胞での自発活動発現機序に関する生理学及び分子学的研究

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Physiological Signiticance of Phospholipase A_2 activation in neuronal activity.Principal Investigator

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[Journal Article] Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivo.2017

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[Journal Article] A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain2012

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[Journal Article] M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum : Findings obtained with muscarinic-receptor knockout mouse2007

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[Journal Article] A mionor role for Ca(2+)sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon2007

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[Journal Article] M_2 and M_3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum : findings obtained using muscarinic receptor knockout mouse.2007

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[Journal Article] M_2 and M_3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: findings obtained using muscarinic receptor knockout mouse2007

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[Journal Article] Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum2007

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[Journal Article] M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ilerm:Findings obtained with muscarinic-receptor knockout mouse2007

) 竹内正吉

TAKEUCHI Tadayoshi 竹内正吉