Takahashi Chiaki 高橋智聡

… Alternative Names

TAKAHASHI Chiaki 高橋智聡

高橋智聡タカハシチアキ

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Researcher Number	50283619
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help	2014 – 2023: 金沢大学, がん進展制御研究所, 教授 2012: 金沢大学, がん進展制御研究所, 教授 2009 – 2011: Kyoto University, がん研究所, 教授 2008: Kyoto University, 医学研究科, 研究員 2006 – 2007: Kyoto University, 医学研究科, 准教授 … More 2005 – 2006: 京都大学, 医学研究科, 助教授 2004: 京都大学, 医学研究科・研究院(COE) 2003: 京都大学, 医学研究科, 研究員(COE) 1999: 京大, 医学(系)研究科, 助手 1998: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Tumor biology / Pathological medical chemistry / Biological Sciences / Biological Sciences / Basic Section 50010:Tumor biology-related / Medium-sized Section 50:Oncology and related fields / Tumor biology and related fields / General medical chemistry / Cell biology Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 54020:Connective tissue disease and allergy-related / Carcinogenesis
Keywords	Principal Investigator がん / RB / がん抑制遺伝子 / Rb / Ras / 代謝 / がん代謝 / 悪性化 / ras / がん遺伝子 … More / 癌抑制遺伝子 / SUCLA2 / 脂質代謝 / 解糖系 / がん幹細胞 / DNA損傷 / セネセンス / metastasis / RECK / RB1 / 腫瘍内不均一性 / 細胞競合 / 乳がん / 炎症 / 糖代謝 / コレステロール / PGAM / イソプレニル化 / ノックアウトマウス / senescence / malignant conversion / tumor suppressor / oncogene / 甲状腺髄様がん / N-ras / 癌遺伝子 / マウス / Rho / 転移 / MMP-2 / MMP-9 / invasion / transform / セラミド / PGAM1,2 / 未分化性 / CDK / AMPK / EGFR / 治療抵抗性 / CDK2/4/6阻害剤 / CDK阻害剤 / ELOVL6 / KRAS阻害剤 / CDK4/6阻害剤 / RAS / ミトコンドリア / 創薬 / 治療 / チモキノン / 前立腺がん / 核酸代謝 / 上皮間葉転換 / NFYA / パッセンジャー欠失 / ゲノム異常 / 創薬標的 / SUCLG2 / 合成致死性 / DNA damage / mdullary thyroiod carcinoma / 甲状腺髄様癌 / がん悪性化 / 微小環境 / ケモカイン / サイトカイン / IL-6 / グルタミン / 抗がん剤 / CAAXモチーフ / ファルネシル化阻害剤 / 脂肪酸 / 脂肪合成系 / 悪性進展 / 前がん病変 / DNA損傷応答 / クロマチンリモデリング / 細胞老化 / stem cells / neural precursor cells / Nestin / Jagged / ADAM10 / シェディング / Delta / 大脳皮質 / MMP / MT1-MMP / ADAM / 神経幹細胞 / Notchリガンド / Notch / Medullary thyroid cancer / LOH / Rh / flat reversion / flat revercion … More Except Principal Investigator レギュカルチン / SNAI / DIP２ / 上皮間葉移行 / 滑膜 / 難治性病態 / 滑膜細胞 / FSTL1 / エピジェネシス / 可塑性 / 関節滑膜 / 上皮間葉転移 / DIP2 / 関節リウマチ / p16Ink4a / 抗がん剤 / がん / エピジェネティック / クロマチンリモデリング / p16^Ink4 / DNMT1 / ATM / Rb Less

レギュカルチンの多機能性を基軸とした疾患発症メカニズムの解明と疾患治療法の開発
- Principal Investigator
  
  村田富保
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
RB1 tumor suppressor functions in metabolismPrincipal Investigator
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Analysis of DIP2C as a novel regulator for epithelial-mesenchymal transition of rheumatoid arthritis synovium and a potential therapeutic target
- Principal Investigator
  
  Tanaka Masao
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto University
Drug development targeting metabolic vulnerability associated with SUCLA2 lossPrincipal Investigator
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kanazawa University
Drug discovery based on collateral lethalityPrincipal Investigator
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  Kanazawa University
RB mosaicism and cell competition in mammary epithelial and cancer cellsPrincipal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Metabolic regulation by RB tumor suppressor genePrincipal Investigator
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
細胞競合を介したがん幹細胞クローン維持機構Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Regulation of metabolism by RB tumor suppressor genePrincipal Investigator
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Inflammatory circuit that triggres malignant progressionPrincipal Investigator
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
The role of Rb-Ras pathway in cancer stem cells
- Principal Investigator
  
  SHAMMA Awad
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Carcinogenesis
- Research Institution
  Kanazawa University
Rbがん抑制遺伝子欠損によって誘導される蛋白質高イソプレニル化の研究Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Analysis of cellular signals toward carcinogenesis and metastasis using genetically modified micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Chiaki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
複合変異マウスを用いたがん化・転移シグナルの研究Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
RECKによるNotchシグナルの上方制御Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Wild type N-ras as a tumor suppressor in human sporadic medullary thyroid cardnomaPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Chiaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
複合変異マウスを用いたがん化・転移シグナルの研究Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
野生型N-ras遺伝子の組織特異的がん抑制効果とその機構Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
フラット・リバージョン誘導遺伝子RECKによるがん転移抑制機構Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
RECK遺伝子によるがん細胞転移抑制機構の解析Principal Investigator
- Principal Investigator
  
  高橋智聡
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University

[Book] 別冊・医学のあゆみ『がん細胞社会における細胞間相互作用Which intercellular interaction should be targeted in cancer therapy?』2021
- Author(s)
  高橋智聡, 河野晋.
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20H03509
[Book] 生体の科学　がん細胞の中の多様性・多層性2016
- Author(s)
  西本裕希、高橋智聡
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26640070
[Book] 生体の科学　がん細胞の中の多様性・多層性2016
- Author(s)
  西本裕希、高橋智聡
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26290037
[Book] 生体の科学　がん細胞の中の多様性・多層性2016
- Author(s)
  西本裕希、高橋智聡
- Publisher
  医学書院
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Book] ニッチ細胞の遺伝子変異が発がんを誘導する？骨芽細胞の場合2014
- Author(s)
  高橋智聡
- Total Pages
  2
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26640070
[Book] ニッチ細胞の遺伝子変異が発がんを誘導する？骨芽細胞の場合2014
- Author(s)
  高橋智聡
- Total Pages
  2
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26290037
[Book] 「Rasシグナル制御と発癌」実験医学増刊号Vol.29 No.2秒進分歩する癌研究と分子標的治療原英二、平尾敦、矢野聖二、佐谷秀行編2011
- Author(s)
  高橋智聡
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390093
[Book] 「その他腫瘍モデル」完全版マウス・ラット疾患モデル活用ハンドブック秋山徹、奥山隆平、河府和義編2010
- Author(s)
  北嶋俊輔、石川智夫、木戸敬治、高橋智聡
- Total Pages
  18
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390093
[Book] Regulation of Notch signaling and its polarity mediated by ectodomain shedding of DSL ligands.(Tanpakushitsu Kakusan Koso(in Japanesse)Oct; 54(13))2009
- Author(s)
  C. Takahashi, T. Muraguchi, Y. Takegami, T. Miki.
- Data Source
  KAKENHI-PROJECT-20012027
[Book] The genetic and biochemical interactions of Rb and ras.(Seikagaku(in Japanese)Oct;81(10))2009
- Author(s)
  C. Takahashi, Y. Takegami, A. Shamma
- Data Source
  KAKENHI-PROJECT-20012027
[Book] 実験医学増刊2004年5月号血管研究の最先端と治療への応用2004
- Author(s)
  高橋智聡
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15659068
[Journal Article] Differential requirement for IL-2 and IL-23 in the differentiation and effector functions of Th17/ILC3-like cells in a human T cell line2024
- Author(s)
  Momtazkari Sarah、Dev Choudhury Anahita、Yong Zachary Wei Ern、Le Dong Thanh、Nguyen Canh Hiep、Harada Kenichi、Hori Toshiyuki、Osato Motomi、Takahashi Chiaki、Koh Cai Ping、Voon Dominic Chih-Cheng
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: - Issue: 6 Pages: 1108-1117
- DOI
  10.1093/jleuko/qiae034
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-23K24165
[Journal Article] Drug-drug conjugates of MEK and Akt inhibitors for RAS-mutant cancers2024
- Author(s)
  Fujita Hikaru、Arai Sachiko、Arakawa Hiroshi、Hamamoto Kana、Kato Toshiyuki、Arai Tsubasa、Nitta Nanaka、Hotta Kazuki、Hosokawa Natsuko、Ohbayashi Takako、Takahashi Chiaki、Inokuma Yasuhide、Tamai Ikumi、Yano Seiji、Kunishima Munetaka、Watanabe Yoshihiro
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 102 Pages: 117674-117674
- DOI
  10.1016/j.bmc.2024.117674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-23K23326, KAKENHI-PROJECT-23K27609
[Journal Article] Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinoma resistant cell.Cell Death & Disease.2023
- Author(s)
  Noguchi M, Kohno S, Pellattiero A, Machida Y, Shibata K, Shintani N, Kohno T, Gotoh N, Takahashi C, Hirao A, Kasahara A, and Scorrano L.
- Journal Title
  
  Cell Death & Disease
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells2023
- Author(s)
  Noyes C, Kitajima S, Li F, Suita Y, Miriyala S, Isaac S, Ahsan N, Knelson E, Vajdi A, Tani T, Thai TC, Xu D, Murai J, NTapinos N, Takahashi C, Barbie DA and Yajima M.
- Journal Title
  
  Commun. Biol
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells.2023
- Author(s)
  Gong L, Voon DC, Nakayama J, Takahashi C and Kohno S.
- Journal Title
  
  Cancer Sci.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells2023
- Author(s)
  Noyes Christopher、Kitajima Shunsuke、Li Fengkai、Suita Yusuke、Miriyala Saradha、Isaac Shakson、Ahsan Nagib、Knelson Erik、Vajdi Amir、Tani Tetsuo、Thai Tran C.、Xu Derek、Murai Junko、Tapinos Nikos、Takahashi Chiaki、Barbie David A.、Yajima Mamiko
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1
- DOI
  10.1038/s42003-023-04444-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line2023
- Author(s)
  Noguchi Masafumi、Kohno Susumu、Pellattiero Anna、Machida Yukino、Shibata Keitaro、Shintani Norihito、Kohno Takashi、Gotoh Noriko、Takahashi Chiaki、Hirao Atsushi、Scorrano Luca、Kasahara Atsuko
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 4 Pages: 1-10
- DOI
  10.1038/s41419-023-05768-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15017, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-23K18237, KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-22K20654, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-21H02671, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-23K27437
[Journal Article] NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism2023
- Author(s)
  Okada Nobuhiro、Ueki Chihiro、Shimazaki Masahiro、Tsujimoto Goki、Kohno Susumu、Muranaka Hayato、Yoshikawa Kiyotsugu、Takahashi Chiaki
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 596-596
- DOI
  10.1038/s42003-023-04987-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07152, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03509
[Journal Article] Inactivation of CSGALNACT2 Promotes Ovarian Cancer Migration and Invasion Through the MAPK/ERK Signaling Pathway.2023
- Author(s)
  4.Ma M, Wu M, Gu S, Yang J, Wang C, Zhang Y, Cheng S, Xu S, Zhang M, Wu Y, Zhao Y, Tian X, Takahashi C, Sheng J, and Wang Y
- Journal Title
  
  Cellular Oncol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice2023
- Author(s)
  Inaba Yuka、Hashiuchi Emi、Watanabe Hitoshi、Kimura Kumi、Oshima Yu、Tsuchiya Kohsuke et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 167-167
- DOI
  10.1038/s41467-023-35804-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19426, KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-20K08860, KAKENHI-PROJECT-23K24764, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-21H02695, KAKENHI-PROJECT-23K24390
[Journal Article] Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat.2022
- Author(s)
  Oo SM, Oo HK, Takayama H, Ishii KA, Takeshita Y, Goto H, Nakano Y, Kohno S, Takahashi C, Nakamura H, Saito Y, Matsushita M, Okamatsu-Ogura Y, Saito M and Takamura T.
- Journal Title
  
  Cell Reports 3
  
  Volume: 38 Pages: 110566-110566
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] NFYA promotes the malignant behavior of triple-negative breast cancer through the regulation of lipid metabolism2022
- Author(s)
  Okada Nobuhiro、Ueki Chihiro、Shimazaki Masahiro、Tsujimoto Goki、Kohno Susumu、Muranaka Hayato、Yoshikawa Kiyotsugu、Takahashi Chiaki
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.05.26.493660
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07152, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03509
[Journal Article] RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia2022
- Author(s)
  Pham Loc Thi、Peng Hui、Ueno Masaya、Kohno Susumu、Kasada Atuso、Hosomichi Kazuyoshi、Sato Takehiro、Kurayoshi Kenta、Kobayashi Masahiko、Tadokoro Yuko、Kasahara Atsuko、Shoulkamy Mahmoud I.、Xiao Bo、Worley Paul F.、Takahashi Chiaki、Tajima Atsushi、Hirao Atsushi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 621 Pages: 74-79
- DOI
  10.1016/j.bbrc.2022.06.089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08448, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H01356, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K16264, KAKENHI-PUBLICLY-21H00342
[Journal Article] Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat.2022
- Author(s)
  Oo SM, Oo HK, Takayama H, Ishii KA, Takeshita Y, Goto H, Nakano Y, Kohno S, Takahashi C, Nakamura H, Saito Y, Matsushita M, Okamatsu-Ogura Y, Saito M and Takamura T.
- Journal Title
  
  Cell Reports
  
  Volume: 38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Targeting Abnormal Cell Cycle in Cancer: A Preface to the Special Issue2022
- Author(s)
  Takahashi Chiaki、Kato Jun-ya
- Journal Title
  
  Onco
  
  Volume: 2 Issue: 1 Pages: 34-35
- DOI
  10.3390/onco2010003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages2021
- Author(s)
  Murata Tomiyasu、Hashimoto Kazunori、Kohno Susumu、Takahashi Chiaki、Yamaguchi Masayoshi、Ito Chihiro、Masataka Itoigawa、Kojima Roji、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 1 Pages: 175-191
- DOI
  10.1002/2211-5463.13321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-19K07092
[Journal Article] Targeting RB1 Loss in Cancers2021
- Author(s)
  Linn Paing、Kohno Susumu、Sheng Jindan、Kulathunga Nilakshi、Yu Hai、Zhang Zhiheng、Voon Dominic、Watanabe Yoshihiro、Takahashi Chiaki
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 15 Pages: 3737-3737
- DOI
  10.3390/cancers13153737
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021
- Author(s)
  Nomura Naho、Ito Chiaki、Ooshio Takako、Tadokoro Yuko、Kohno Susumu、Ueno Masaya、Kobayashi Masahiko、Kasahara Atsuko、Takase Yusuke、Kurayoshi Kenta、Si Sha、Takahashi Chiaki、Komatsu Masaaki、Yanagawa Toru、Hirao Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1666-1679
- DOI
  10.1038/s41598-021-81076-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07566, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19H03846, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07558
[Journal Article] Treatment of Retinoblastoma 1?Intact Hepatocellular Carcinoma With Cyclin‐Dependent Kinase 4/6 Inhibitor Combination Therapy2021
- Author(s)
  Sheng Jindan、Kohno Susumu、Okada Nobuhiro、Okahashi Nobuyuki、Teranishi Kana、Matsuda Fumio、Shimizu Hiroshi、Linn Paing、Nagatani Naoko、Yamamura Minako、Harada Kenichi、Horike Shin‐ichi、Inoue Hiroshi、Yano Seiji、Kumar Sharad、Kitajima Shunsuke、Ajioka Itsuki、Takahashi Chiaki
- Journal Title
  
  Hepatology
  
  Volume: 74 Issue: 4 Pages: 1971-1993
- DOI
  10.1002/hep.31872
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07365, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-20K07612
[Journal Article] Synthetic inhibitors of CDK4/6 activities and tumor suppression: a preface to the special issue.2021
- Author(s)
  Takahashi C and Kato J.
- Journal Title
  
  Onco
  
  Volume: 1 Issue: 1 Pages: 1-2
- DOI
  10.3390/onco1010001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555
[Journal Article] GDE2-RECK controls ADAM10 α-secretase mediated cleavage of amyloid precursor protein2021
- Author(s)
  Nakamura Mai、Li Yuhan、Choi Bo-Ran、Matas-Rico Elisa、Troncoso Juan、Takahashi Chiaki、Sockanathan Shanthini
- Journal Title
  
  Science Translational Medicine
  
  Volume: 13 Issue: 585
- DOI
  10.1126/scitranslmed.abe6178
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Reduced RECK levels accelerate skeletal muscle differentiation, improve muscle regeneration, and decrease fibrosis2021
- Author(s)
  Gutierrez Jaime、Gonzalez David、Escalona‐Rivano Rodrigo、Takahashi Chiaki、Brandan Enrique
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 5
- DOI
  10.1096/fj.202001646rr
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Tumor Milieu Controlled by RB Tumor Suppressor.2020
- Author(s)
  Kitajima S, Li F, Takahashi C.
- Journal Title
  
  Int J Mol Sci.,
  
  Volume: 21 Issue: 7 Pages: 1-1
- DOI
  10.3390/ijms21072450
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion2020
- Author(s)
  Kohno Susumu、Linn Paing、Nagatani Naoko、Watanabe Yoshihiro、Kumar Sharad、Soga Tomoyoshi、Takahashi Chiaki
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 34 Pages: 5690-5707
- DOI
  10.1038/s41388-020-1381-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-16H06276
[Journal Article] Peripubertal high‐fat diet promotes c‐Myc stabilization in mammary gland epithelium2020
- Author(s)
  Kulathunga Nilakshi、Kohno Susumu、Linn Paing、Nishimoto Yuuki、Horike Shin‐ichi、Zaraiskii Mikhail I.、Kumar Sharad、Muranaka Hayato、Takahashi Chiaki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 7 Pages: 2336-2348
- DOI
  10.1111/cas.14492
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555
[Journal Article] mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.2020
- Author(s)
  Thumkeo, D., Katsura, Y., Nishimura, Y., Kanchanawong, P., Tohyama, K., Ishizaki, T., Kitajima, S., Takahashi, C., Hirata, T., Watanabe, N., Krummel, M. F., and Narumiya, S.
- Journal Title
  
  Sci. Adv.
  
  Volume: 6 Issue: 1 Pages: 2432-2432
- DOI
  10.1126/sciadv.aay2432
- NAID
  120006777011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07621, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K08339, KAKENHI-PROJECT-17K08591, KAKENHI-PROJECT-19H01020, KAKENHI-PROJECT-20H03509
[Journal Article] MicroRNA in monitoring of the evolution of glial cerebral tumors.2020
- Author(s)
  Seliverstov RY, Zaraiskiy MI, Tyurin RV, Naryshkin AG, Valerko VG, Semiglazov VV and Takahashi C.
- Journal Title
  
  Siberian Journal of Oncology
  
  Volume: 19 Issue: 3 Pages: 47-53
- DOI
  10.21294/1814-4861-2020-19-3-47-53
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Journal Article] Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells2020
- Author(s)
  Murata Tomiyasu、Yamaguchi Masayoshi、Kohno Susumu、Takahashi Chiaki、Risa Watanabe、Hatori Kanna、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 10 Issue: 10 Pages: 1967-1984
- DOI
  10.1002/2211-5463.12947
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K07092
[Journal Article] Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion2019
- Author(s)
  Li Fengkai、Kitajima Shunsuke、Kohno Susumu、Yoshida Akiyo、Tange Shoichiro、Sasaki Soichiro、Okada Nobuhiro、Nishimoto Yuuki、Muranaka Hayato、Nagatani Naoko、Suzuki Misa、Masuda Sayuri、Thai Tran C.、Nishiuchi Takumi、Tanaka Tomoaki、Barbie David A.、Mukaida Naofumi、Takahashi Chiaki
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 15 Pages: 3903-3915
- DOI
  10.1158/0008-5472.can-18-3604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-19H03708
[Journal Article] Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.2018
- Author(s)
  Zhao J, Okamoto Y, Asano Y, Ishimaru K, Aki S, Yoshioka K, Takuwa N, Wada T, Inagaki Y, Takahashi C, Nishiuchi T, Takuwa Y.
- Journal Title
  
  PLoS One
  
  Volume: 13(5)
- NAID
  120006605152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05615
[Journal Article] Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.2018
- Author(s)
  Zhao J, Okamoto Y, Asano Y, Ishimaru K, Aki S, Yoshioka K, Takuwa N, Wada T, Inagaki Y, Takahashi C, Nishiuchi T, Takuwa Y.
- Journal Title
  
  PLoS One
  
  Volume: 13(5)
- NAID
  120006605152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19586
[Journal Article] Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.2018
- Author(s)
  Zhao J, Okamoto Y, Asano Y, Ishimaru K, Aki S, Yoshioka K, Takuwa N, Wada T, Inagaki Y, Takahashi C, Nishiuchi T, Takuwa Y.
- Journal Title
  
  PLoS One
  
  Volume: 13(5)
- NAID
  120006605152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03576
[Journal Article] Regucalcin confers resistance to amyloid-β toxicity in neuronally differentiated PC12 cells2018
- Author(s)
  Murata Tomiyasu、Yamaguchi Masayoshi、Kohno Susumu、Takahashi Chiaki、Kakimoto Mitsumi、Sugimura Yukiko、Kamihara Mako、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Issue: 3 Pages: 349-360
- DOI
  10.1002/2211-5463.12374
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-16K08252
[Journal Article] Involvement of prokineticin 2-expressing neutrophil infiltration in 5-fluorouracil-induced aggravation of breast cancer metastasis to lung.2018
- Author(s)
  Sasaki S, Baba T, Muranaka H, Tanabe Y, Takahashi C, Matsugo S, Mukaida N.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 印刷中 Issue: 7 Pages: 1515-1525
- DOI
  10.1158/1535-7163.mct-17-0845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08733, KAKENHI-PROJECT-17K07159, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17J06054, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-18K15237
[Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22018
- Author(s)
  Nishimura Tatsunori、Nakata Asuka、Chen Xiaoxi、Nishi Kurumi、Meguro-Horike Makiko、Sasaki Soichiro、Kita Kenji、Horike Shin-ichi、Saitoh Kaori、Kato Keiko、Igarashi Kaori、Murayama Takahiko、Kohno Susumu、Takahashi Chiaki、Mukaida Naofumi、Yano Seiji、Soga Tomoyoshi、Tojo Arinobu、Gotoh Noriko
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 14 Pages: 2464-2481
- DOI
  10.1038/s41388-018-0589-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19587, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-17K15021, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H03576
[Journal Article] Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS2018
- Author(s)
  Kitajima Shunsuke et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 34 Issue: 3 Pages: 439-452.e6
- DOI
  10.1016/j.ccell.2018.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K19586
[Journal Article] Glucoraphanin ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice.2017
- Author(s)
  Nagata N, Xu L, Kohno S, Ushida Y, Aoki Y, Umeda R, Fuke N, Zhuge F, Ni Y, Nagashimada M, Takahashi C, Suganuma H, Kaneko S and Ota T.
- Journal Title
  
  Diabetes
  
  Volume: 印刷中 Issue: 5 Pages: 1222-1236
- DOI
  10.2337/db16-0662
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K00813, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-17H03576
[Journal Article] The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.2017
- Author(s)
  Kitajima S, Yoshida A, Susumu K, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Hayato M, Wan Y, Thai T C, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen M E, Barbie D A, Hirose O, Tanaka T and Takahashi C.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Journal Article] MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6.2017
- Author(s)
  Yoshida A, Kitajima S, Li F, Chaoyang C, Yujiro T, Susumu K, Wan Y, Naoyuki H, Hayato M, Nishimoto Y, Nagatani N, Nishiuchi T, Thai T C, Suzuki S, Nakao S, Tanaka T, Hirose O, Barbie D A and Takahashi C.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Issue: 8 Pages: 13872-85
- DOI
  10.18632/oncotarget.14681
- NAID
  120006226780
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26430105, KAKENHI-PROJECT-16KK0197, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576
[Journal Article] The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.2017
- Author(s)
  Kitajima S, Yoshida A, Susumu K, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Hayato M, Wan Y, Thai T C, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen M E, Barbie D A, Hirose O, Tanaka T and Takahashi C
- Journal Title
  
  Oncogene
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] The RB?IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity2017
- Author(s)
  Kitajima S、Yoshida A、Kohno S、Li F、Suzuki S、Nagatani N、Nishimoto Y、Sasaki N、Muranaka H、Wan Y、Thai T C、Okahashi N、Matsuda F、Shimizu H、Nishiuchi T、Suzuki Y、Tominaga K、Gotoh N、Suzuki M、Ewen M E、Barbie D A、Hirose O、Tanaka T、Takahashi C
- Journal Title
  
  Oncogene
  
  Volume: 36 Issue: 36 Pages: 5145-5157
- DOI
  10.1038/onc.2017.124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16J40231, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling2017
- Author(s)
  Muranaka H、Hayashi A、Minami K、Kitajima S、Kohno S、Nishimoto Y、Nagatani N、Suzuki M、Kulathunga L A N、Sasaki N、Okada N、Matsuzaka T、Shimano H、Tada H、Takahashi C
- Journal Title
  
  Oncogenesis
  
  Volume: 6 Issue: 6 Pages: e350-e350
- DOI
  10.1038/oncsis.2017.51
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance.2017
- Author(s)
  Hegazy AM, Yamada D, Kobayashi M, Kohno S, Ueno M, Ali MA, Ohta K, Tadokoro Y, Ino Y, Todo T, Soga T, Takahashi C and Hirao A.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 21496-21509
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Journal Article] Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation2017
- Author(s)
  Kitajima Shunsuke、Takahashi Chiaki
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 9 Pages: 1726-1731
- DOI
  10.1111/cas.13312
- NAID
  120006370944
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576
[Journal Article] RB tumor suppressor functions shared by stem cell and cancer cell strategies.2016
- Author(s)
  Kohno S, Kitajima S, Sasaki N and Takahashi C.
- Journal Title
  
  World J Stem Cells
  
  Volume: 8 Issue: 4 Pages: 170-184
- DOI
  10.4252/wjsc.v8.i4.170
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K18404
[Journal Article] Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance.2016
- Author(s)
  Hegazy AM, Yamada D, Kobayashi M, Kohno S, Ueno M, Ali MA, Ohta K, Tadokoro Y, Ino Y, Todo T, Soga T, Takahashi C and Hirao A.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 170-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] Pleiotropic functions of RB protein in tumor suppression.2015
- Author(s)
  Hayashi N. and Takahashi C.
- Journal Title
  
  Archives in Cancer Res
  
  Volume: epub
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Journal Article] Primary Culture of Mouse Thyroid Calcitonin-producing Cell (C cell) Tumors.2015
- Author(s)
  Kitajima S, Li F, Takahashi C.
- Journal Title
  
  Bio-Protocol
  
  Volume: 5-24
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Journal Article] Undifferentiated State Induced by Rb-P53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts2015
- Author(s)
  Kitajima S, Kohno S, Kondoh A, Sasaki N, Nishimoto Y, Li F, Mohammed MS, Muranaka H, Nagatani N, Suzuki M, Kido Y, Takahashi C
- Journal Title
  
  STEM CELLS
  
  Volume: - Issue: 5 Pages: 1657-1669
- DOI
  10.1002/stem.1971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25830076, KAKENHI-PROJECT-25830077, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037
[Journal Article] Pleiotropic functions of RB protein in tumor suppression.2015
- Author(s)
  Hayashi N. and Takahashi C.
- Journal Title
  
  Archives in Cancer Res
  
  Volume: epub
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26640070
[Journal Article] An in vitro system to characterize prostate cancer progression identified signaling required for self-renewal.2015
- Author(s)
  Salah M, Nishimoto Y, Kohno S, Kondoh A, Kitajima S, Muranaka H, Nishiuchi T, Ibrahim A, Yoshida A, Takahashi C.
- Journal Title
  
  Mol Carcinog.
  
  Volume: in press Issue: 12 Pages: 1974-1989
- DOI
  10.1002/mc.22444
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Journal Article] Primary Culture of Mouse Thyroid Calcitonin-producing Cell (C cell) Tumors.2015
- Author(s)
  Kitajima S, Li F, Takahashi C.
- Journal Title
  
  Bio-Protocol
  
  Volume: 5-24
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] RB tumor suppressor functions shared by stem cell and cancer cell strategies.2015
- Author(s)
  Kohno S, Kitajima S, Sasaki N and Takahashi C.
- Journal Title
  
  World J Stem Cells
  
  Volume: 8 Pages: 170-184
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26640070
[Journal Article] RECK-mediated β1-integrin regulation by TGF-β1 is critical for wound contraction in mice.2015
- Author(s)
  Gutierrez J, Droppelmann CA, Contreras O, Takahashi C and Brandan E.
- Journal Title
  
  PLoS One
  
  Volume: Aug 6 Issue: 8 Pages: e0135005-e0135005
- DOI
  10.1371/journal.pone.0135005
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Journal Article] Pleiotropic functions of RB protein in tumor suppression.2015
- Author(s)
  Hayashi N. and Takahashi C.
- Journal Title
  
  Archives in Cancer Res
  
  Volume: epub
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] Primary Culture of Mouse Thyroid Calcitonin-producing Cell (C cell) Tumors.2015
- Author(s)
  Kitajima S, Li F, Takahashi C.
- Journal Title
  
  Bio-Protocol
  
  Volume: 5-24
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26640070
[Journal Article] Metabolic characterization of cultured mammalian cells by mass balance analysis, tracer labeling experiments and computer-aided simulations.2015
- Author(s)
  Okahashi N, Kohno S, Kitajima S, Matsuda F, Takahashi C, Shimizu H.
- Journal Title
  
  J Biosci Bioeng.
  
  Volume: 120 Issue: 6 Pages: 725-731
- DOI
  10.1016/j.jbiosc.2015.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-15J05988, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Journal Article] Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients.2014
- Author(s)
  Ali MA, Naka K, Yoshida A, Fuse K, Kasada A, Hoshii T, Tadokoro Y, Ueno M, Ohta K, Kobayashi M, Takahashi C, Hirao A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 450 Issue: 1 Pages: 837-843
- DOI
  10.1016/j.bbrc.2014.06.066
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26460361, KAKENHI-PROJECT-26640070
[Journal Article] Retinoblastoma Protein and MyoD Function Together to Effect the Repression of Fra-1 and In Turn Cyclin D1 During Terminal Cell Cycle Arrest Associated with Myogenesis.2014
- Author(s)
  Rajabi H M, Takahashi C and Ewen M E.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 34 Pages: 23417-23427
- DOI
  10.1074/jbc.m113.532572
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26640070
[Journal Article] Reversion-inducing cysteine-rich protein with Kazal motifs interferes withepidermal growth factor receptor signaling.2011
- Author(s)
  S.Kitajima, T.Miki, Y.Takegam, Y.Kido, M.Noda, E.Hara, A.Shamma , C.Takahashi.
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 737-750
- NAID
  120002907445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500998
[Journal Article] Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling.2011
- Author(s)
  Kitajima S, Miki T, Takegami Y, Kido Y, Noda M, Hara E, Shamma A, Takahashi C.
- Journal Title
  
  Oncogene
  
  Volume: 30(6) Pages: 737-750
- NAID
  120002907445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling2011
- Author(s)
  S.Kitajima, T.Miki, Y.Takegam, Y.Kido, M.Noda, E.Hara, A.Shamma, C.Takahashi
- Journal Title
  
  Oncogene
  
  Volume: 30 Issue: 6 Pages: 737-750
- DOI
  10.1038/onc.2010.448
- NAID
  120002907445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500998
[Journal Article] The bl-integrin-dependent function of BECK in physiologic and tumor anglogenesls.2010
- Author(s)
  T.Miki, A.Shamma, S.Kitajima, Y.Takegami, M.Noda, Y.Nakashima, K.Watanabe , C.Takahashi.
- Journal Title
  
  Mol.Cancer Res.
  
  Volume: 8 Pages: 665-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500998
[Journal Article] The β1-integrin-dependent function of RECK in physiologic and tumor angiogenesis.2010
- Author(s)
  T.Miki, A.Shamma, S.Kitajima, Y.Takegami, M.Noda, Y.Nakashima, K.Watanabe, C.Takahashi.
- Journal Title
  
  Mol.Cancer Res. (印刷中)
- NAID
  120002224338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] The β1-integrin-dependent function of RECK in physiologic and tumor angiogenesis.2010
- Author(s)
  Miki T, Shamma A, Kitajima S,Takegami Y, Noda M, Nakashima Y, Watanabe K, Takahashi C.
- Journal Title
  
  Mol.Cancer Res.
  
  Volume: 8(5) Pages: 665-676
- NAID
  120002224338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Hypoxia and RAS signaling pathways converge on, and cooperatively down-regulate, the RECK tumor suppressor protein via microRNAs.2010
- Author(s)
  F.Loayza-Puch, Y.Yoshida, T.Matsuzaki, C.Takahashi, H.Kitayama, M.Noda.
- Journal Title
  
  Oncogene
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] The・β1-integrin-dependent function of RECK in physiologic and tumor angiogenesis2010
- Author(s)
  T. Miki, A. Shamma, S. Kitajima, Y. Takegami, M. Noda, Y. Nakashima, K. Watanabe, C. Takahashi
- Journal Title
  
  Mol. Cancer Res.
- NAID
  120002224338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] The β1-integrin-dependent function of RECK in physiologic and tumorangiogenesis2010
- Author(s)
  T.Miki, A.Shamma, S.Kitajima, Y.Takegami, M.Noda, Y.Nakashima, K.Watanabe, C.Takahashi
- Journal Title
  
  Mol.Cancer Res. (印刷中)
- NAID
  120002224338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice.2010
- Author(s)
  Chandana EP, Maeda Y, Ueda A, Kiyonari H, Oshima N,Yamamoto M, Kondo S, Oh J, Takahashi R, Yoshida Y, Kawashima S, Alexander DB, Kitayama H, Takahashi C, Tabata Y, Matsuzaki T, Noda M.
- Journal Title
  
  BMC Dev Biol.
  
  Volume: 10 Pages: 84-84
- NAID
  120002511238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Hypoxia and RAS signaling pathways converge on, and cooperatively down-regulate, the RECK tumor suppressor protein via microRNAs.2010
- Author(s)
  F. Loayza-Puch, Y. Yoshida, T. Matsuzaki, C. Takahashi, H. Kitayama, M. Noda.
- Journal Title
  
  Oncogene
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] Hypoxia and RAS signaling pathways converge on, and cooperatively down-regulate, the RECK tumor suppressor protein via microRNAs2010
- Author(s)
  F.Loayza-Puch, Y.Yoshida, T.Matsuzaki, C.Takahashi, H.Kitayama, M.Noda
- Journal Title
  
  Oncogene (オンライン)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] What we learn from transformation suppressor genes : lessons from RECK.2010
- Author(s)
  Noda M, Takahashi C, Matsuzaki T, Kitayama H.
- Journal Title
  
  Future Oncol.
  
  Volume: 6(7) Pages: 1105-1116
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs.2010
- Author(s)
  Loayza-Puck F, Yoshida Y, Matsuzaki T, Takahashi C, Kitayama H, Noda M.
- Journal Title
  
  Oncogene
  
  Volume: 29(18) Pages: 2638-2648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Regulation of Notch signaling and its polarity mediated by ectodomain shedding of DSL ligands.2009
- Author(s)
  C.Takahashi, T.Muraguchi, Y.Takegami, T.Miki.
- Journal Title
  
  Tanpakushitsu Kakusan Koso (in Japanese) 54(13)
  
  Pages: 1742-1746
- NAID
  40016835263
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] Rb regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-Ras Isoprenylation.2009
- Author(s)
  A. Shamma, Y. Takegami, T. Miki, S. Kitajima, M. Noda, T. Obara, T. Okamoto, C. Takahashi
- Journal Title
  
  Cancer Cell 15
- NAID
  120001546496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] RECK forms cowbell-shaped dimmers and inhibits MMP-catalyzed cleavage of fibronectin.2009
- Author(s)
  A.Omura, T.Matsuzaki, K.Miio, T.Ogura, M.Yamamoto, A.Fujita, K.Okawa, H.Kitayama, C.Takahashi, C.Sato, M.Noda.
- Journal Title
  
  J.Biol. Chem. 284
  
  Pages: 3461-3169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] Rb regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-Ras Isoprenylation.2009
- Author(s)
  A. Shamma, Y. Takegami, T. Miki, S. Kitajima, M. Noda, T. Obara, T. Okamoto, C. Takahashi
- Journal Title
  
  Cancer Cell 15
  
  Pages: 255-269
- NAID
  120001546496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] Rb regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-Ras Isoprenylation.2009
- Author(s)
  A.Shamma, Y.Takegami, T.Miki, S.Kitajima, M.Noda, T.Obara, T.Okamoto, C.Takahashi.
- Journal Title
  
  Cancer Cell 15
  
  Pages: 255-269
- NAID
  120001546496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] RECK forms cowbell-shaped dimmers and inhibits MMP-catalyzed cleavage of fibronectin2009
- Author(s)
  A. Omura, T Matsuzaki, K. Milo, T. Ogura, M. Yamamoto, A. Fujita, K. Okawa, H. Kitayama, C. Takahashi, C. Sato and M. Nods
- Journal Title
  
  J. Biol. Chem 284
  
  Pages: 3461-3469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] RECK forms cowbell-shaped dimmers and inhibits MMP-catalyzed cleavage of fibronectin.2009
- Author(s)
  A. Omura, T Matsuzaki, K. Miio, T. Ogura, M. Yamamoto, A. Fujita, K. Okawa, H. Kitayama, C. Takahashi, C. Sato, M. Noda.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 3461-3169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] The genetic and biochemical interactions of Rb and ras.2009
- Author(s)
  C.Takahashi, Y.Takegami, A.Shamma.
- Journal Title
  
  Seikagaku (in Japanese) 81(10)
  
  Pages: 873-883
- NAID
  10026298655
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] RECK forms cowbell-shaped dimmers and inhibits MMP-catalyzed cleavage of fibronectin.2009
- Author(s)
  A. Omura, T Matsuzaki, K. Miio, T. Ogura, M. Yamamoto, A, Fujita, K. Okawa, H. Kitayama, C. Takahashi, C. Sato, M. Noda
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 3461-3469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Rb regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-Ras Isoprenylation2009
- Author(s)
  A.Shamma, Y.Takegami, T.Miki, S.Kitajima, M.Noda, T.Obara, T.Okamoto, C.Takahashi
- Journal Title
  
  Cancer Cell 15
  
  Pages: 255-269
- NAID
  120001546496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Rb regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-Ras Isoprenylation2009
- Author(s)
  A. Shamma, Y. Takegami, T, Miki, S. Kitajima, M. Noda, T. Ohara, T. Okamoto and C. Takahashi
- Journal Title
  
  Cancer Cell 15
- NAID
  120001546496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] The genetic and biochemical interactions of Rb and ras2009
- Author(s)
  C.Takahashi, Y.Takegami, A.Shamma
- Journal Title
  
  Seikagaku (in Japanese) 81(10)
  
  Pages: 873-883
- NAID
  10026298655
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Regulation of Notch signaling and its polarity mediated by ectodomain shedding of DSL ligands2009
- Author(s)
  C.Takahashi, T.Muraguchi, Y.Takegami, T.Miki
- Journal Title
  
  Tanpakushitsu Kakusan Koso (in Japanese) 54(13)
  
  Pages: 1742-1746
- NAID
  40016835263
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] RECK forms cowbell-shaped dimmers and inhibits MMP-catalyzed cleavage of fibronectin2009
- Author(s)
  A.Omura, T.Matsuzaki, K.Miio, T.Ogura, M.Yamamoto, A.Fujita, K.Okawa, H.Kitayama, C.Takahashi, C.Sato, M.Noda
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 3461-3169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390093
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E, Adachi, C. Takahashi and M. Noda
- Journal Title
  
  J. Neurochem. 104
  
  Pages: 376-385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions.2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E. Adachi, C. Takahashi, M. Noda
- Journal Title
  
  J. Neurochera. 104
  
  Pages: 376-385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Localization of the membrane-anchored MMP-regulator BECK at the neuromuscular junctions2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E. Adachi, C. Takahashi and M. Noda
- Journal Title
  
  J. Neurochem. 104
  
  Pages: 376-385
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions.2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E. Adachi, C. Takahashi, M. Noda
- Journal Title
  
  J. Neurochem. 104
  
  Pages: 376-385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E. Adachi, C. Takahashi and M. Noda
- Journal Title
  
  J. Neurochem. 104
  
  Pages: 376-385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E. Adachi, C. Takahashi and M. Noda
- Journal Title
  
  J. Neurochem 104
  
  Pages: 376-385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012027
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions2008
- Author(s)
  S. Kawashima, T. Noda, E. Chandana, Y. Imamura, R. Takahashi, E. Adachi, C. Takahashi and M. Noda
- Journal Title
  
  J. Neurochem. 104
  
  Pages: 376-385
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions2008
- Author(s)
  S., Kawashima, T., Noda, E., Chandana, Y., Imamura, R., Takahashi, E., Adachi, C., Takahashi, M., Noda
- Journal Title
  
  J. Neurochem 104 :
  
  Pages: 376-385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK modulates the Notch signal during cortical neurogenesis2007
- Author(s)
  T., Muraguchi, Y., Takegami, E. P. S., Chandana, S., Kitajima, A., Omura, T., Mild, R., Takahashi, N., Matsumoto, A., Ludwig, M., Noda,C., Takahashi
- Journal Title
  
  Nature Neuroscience 10 :
  
  Pages: 836-845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK regulates cell surface activity of MT1-MMP and CD13 by dual mechanisms2007
- Author(s)
  T. Miki, Y. Takegami, K. Okawa, T. Muraguchi, M. Nodaand C. Takahashi
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 12341-12352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Wild-type NRas and KRas perform distinct functions during transformation2007
- Author(s)
  P. P. Fotiadou, C. Takahashi, H. N. Rajabi, M. E. Ewen
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 6742-6755
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Wild-type NRas and KRas perform distinct functions during transformation2007
- Author(s)
  P. P. Fotiadou, C. Takahashi, H. N. Rajabi, M. E. Ewen
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 6742-6755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Recklessness as a hallmark of aggressive cancer (review)2007
- Author(s)
  M. Noda and C. Takahashi
- Journal Title
  
  Cancer Sci. 104
  
  Pages: 1659-1665
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity2007
- Author(s)
  T. Muraguchi, Y. Takegami, E. P. S. Chandana, S. Kitajima, A. Omura, T. Miki, R. Takahashi, N. Matsumoto, A. Ludwig, M. Noda and C. Takahashi
- Journal Title
  
  Nature Neuroscience 10
  
  Pages: 838-845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK regulates cell surface activity of MT1-MMP and CD13 by dual mechanisms2007
- Author(s)
  T., Miki, Y., Takegami, K, Okawa, T., Muraguchi, M., Noda, C., Takahashi
- Journal Title
  
  J. Biol.Chem. 282
  
  Pages: 12341-12352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity2007
- Author(s)
  T. Muraguchi, Y. Takegami, E. P. S. Chandana, S. Kitajima, A. Omura, T. Miki, R. Takahashi, N. Matsumoto, A. Ludwig, M. Noda and C. Takahashi
- Journal Title
  
  Nature Neurosci. 10
  
  Pages: 838-845
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK regulates cell surface activity of MT1-MMP and CD13 by dual mechanisms2007
- Author(s)
  T. Miki, Y. Takegami, K. Okawa, T. Muraguchi, M. Noda and C. Takahashi
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 12341-12352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity2007
- Author(s)
  T. Muraguchi, Y. Takegami, E.P.S. Chandana, S. Kitajima, A. Omura, T. Miki, R. Takahashi, N. Matsumoto, A. Ludwig, M. Noda and C. Takahashi
- Journal Title
  
  Nature Neuroscience 10
  
  Pages: 838-845
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endncvtic pathwevs.2007
- Author(s)
  T.Miki, Y.Takegami, K.Okawa, T.Muraguchi, M.Noda, C.Takahashi.
- Journal Title
  
  J.Biol.Chem. 28.Feb(オンライン版)
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Recklessness as a hallmark of aggressive cancer (review)2007
- Author(s)
  M. Noda and C. Takahashi
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1659-1665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity2007
- Author(s)
  T. Muraguchi, Y. Takegami, E. P. S. Chandana, S. Kitajima, A. Omura, T. Miki, R. Takahashi, N. Matsumoto, A. Ludwig, M. Noda and C. Takahashi
- Journal Title
  
  Nature Neurosclenoe 10
  
  Pages: 838-845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Recklessness as a hallmark of aggressive cancer2007
- Author(s)
  M., Noda, C., Takahashi
- Journal Title
  
  Cancer set 98
  
  Pages: 1659-1665
- NAID
  10020118454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK regulates cell surface activity of MT1-MMP and CD13 by dual mechanisms2007
- Author(s)
  T. Miki, Y. Takegami, K. Okawa, T. Muraguchi, M. Noda and C. Takahashi
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 12341-12352
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Recklessness as a hallmark of aggressive cancer (review)2007
- Author(s)
  M. Noda and c. Takahashi
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1659-1665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Recklessness as a hallmark of aggressive cancer(review)2007
- Author(s)
  M. Noda and C. Takahashi
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1659-1665
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] RECK regulates cell surface activity of MT1-MMP and CD13 by dual mechanisms2007
- Author(s)
  T. Miki, Y. Takegami, K. Okawa, T. Muraguchi, M. Noda and C. Takahashi
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 12341-12352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] BECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity2007
- Author(s)
  T. Muraguchi, Y. Takegami, E. P. S. Chandana, S. Kitajima, A. Omura, T. Miki, R. Takahashi, N. Matsumoto, A. Ludwig, M. Noda and C. Takahashi
- Journal Title
  
  Nature Neuroscience 10
  
  Pages: 838-845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Wild-type NRas and KRas perform distinct functions during transformation2007
- Author(s)
  P. P. Fotiadou, C. Takahashi, H. N. Rajabi, M. E. Ewen
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 6742-6755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Wild-type NRas and KRas perform distinct functions during transformation2007
- Author(s)
  P.P. Fotiadou. C. Takahashi. H.N. Rajabi, M.E. Ewen
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 6742-6755
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Wild-type NRas and KRas perform distinct functions during transformation2007
- Author(s)
  P. P., Fotiadou, C., Takahashi, H. N., Rajabi, M. E., Ewen
- Journal Title
  
  Mol. Celt Biol. 27
  
  Pages: 6742-6755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endocytic pathways.2007
- Author(s)
  T.Miki, Y.Takegami, K.Okawa, T.Muraguchi, M.Noda, C.Takahashi
- Journal Title
  
  J.Biol.Chem. 28.Feb(オンライン版)
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] MMP-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in the rodent2006
- Author(s)
  K. Nakaji, M. Ihara, C. Takahashi, S. Itohara, M. Noda, R. Takahashi and H. Tomimoto
- Journal Title
  
  Stroke 37
  
  Pages: 2816-23
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Nras loss induces metastatic conversion of Rbl-deficient neuroendocrine thyroid tumor.2006
- Author(s)
  C.Takahashi, B.Contreras, T.Iwanaga, Y.Takegami, A.Bakker, R.T.Bronson, M.Node, M.Loda, J.L.Hunt, M.E.Ewen
- Journal Title
  
  Nature Genetics 38
  
  Pages: 118-123
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Genetic Interaction between Rb and N-ras : Differentiation Control and Metastasis2006
- Author(s)
  M. E., Ewen, C., Takahashi
- Journal Title
  
  Cancer Res 66
  
  Pages: 9345-9348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] MMP-2 plays a critical role in the pathogenesis of white matter lesions alter chronic cerebral hypoperfusion in the rodent2006
- Author(s)
  K, Nakaji, M., lhara, C., Takahashi. S., Itohara, M., Noda, R., Takahashi, H., Tomimoto
- Journal Title
  
  Stroke 37
  
  Pages: 2816-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Genetic Interaction between Rb and N-ras : Differentiation Control and Metastasis.2006
- Author(s)
  M.E.Ewen, C.Takahashi.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 9345-9348
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] MMP-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in the rodent.2006
- Author(s)
  K.Nakaji, H.Ihara, C.Takahashi, S.Itohara, M.Node, R.Takahashi, H.Tomimoto.
- Journal Title
  
  Stroke 37
  
  Pages: 2816-2823
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Nras loss induces metastatic conversion of Rbl- deficient neuroendocrine thyroid tumor2006
- Author(s)
  C., Takahashi, B., Contreras, T., Iwanaga, Y., Takegami, A., Bakker, R. T., Bronson, M., Noda, M., Loda, J. L., Hunt, M. E., Ewen
- Journal Title
  
  Nature Genetics 38
  
  Pages: 118-123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.2006
- Author(s)
  C.Takahashi, B.Contreras, T.Iwanaga, Y.Takegami, A.Bakker, R.T.Bronson, M.Noda, M.Loda, J.L.Hunt, M.E.Ewen.
- Journal Title
  
  Nature Genetics 38
  
  Pages: 118-123
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor2006
- Author(s)
  C. Takahashi, B. Contreras, T. Iwanaga, Y. Takegami, A. Bakker, R. T. Bronson, M. Noda, M. Loda, J. L. Hunt, M. E. Ewen
- Journal Title
  
  Nature Genetics 38
  
  Pages: 118-123
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor2006
- Author(s)
  Takahashi Cら
- Journal Title
  
  Nature Genetics 38
  
  Pages: 118-123
- Data Source
  KAKENHI-PROJECT-17013050
[Journal Article] Genetic Interaction between Rb and N-ras : Differentiation Control and Metastasis.2006
- Author(s)
  M.E.Ewen, C.Takahashi.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 9345-9348
- Data Source
  KAKENHI-PROJECT-18659085
[Journal Article] Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor2006
- Author(s)
  Takahashi Cら
- Journal Title
  
  Nature Genetics 38
  
  Pages: 118-123
- Data Source
  KAKENHI-PROJECT-15659068
[Journal Article] MMP-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in the rodent.2006
- Author(s)
  K.Nakaji, A.Ihara, C.Takahashi, S.Itohara, M.Noda, R.Takahashi, H.Tomimoto.
- Journal Title
  
  Stroke 37
  
  Pages: 2816-2823
- Data Source
  KAKENHI-PROJECT-18012025
[Journal Article] Genetic Interaction between Rb and N-ras: Differentiation Control and Metastasis2006
- Author(s)
  M. E. Ewen and C. Takahashi
- Journal Title
  
  Cancer Res. 66
  
  Pages: 9345-9348
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390101
[Journal Article] Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression2004
- Author(s)
  C.Takahashiら
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 10406-10415
- Data Source
  KAKENHI-PROJECT-15659068
[Journal Article] ATM mediates pRB function to control DNMT1 protein stability and DNA methylation
- Author(s)
  Shamma A., Suzuki M., Hayashi N., Kobayashi M., Sasaki N., Nishiuchi T., Doki Y., Okamoto T., Kohno S., Muranaka H, Kitajima S.,Yamamoto K., Takahashi C
- Journal Title
  
  Molecular and Cellular Biology
- NAID
  120005312327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500998
[Patent] ＲＢ１陽性癌の治療用医薬組成物及びキット2020
- Inventor(s)
  高橋智聡、河野晋、盛金丹
- Industrial Property Rights Holder
  高橋智聡、河野晋、盛金丹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-180429
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K22555
[Patent] SUCLA2遺伝子欠失前立腺がんを特異的に死滅させる化合物2019
- Inventor(s)
  高橋智聡、河野晋、Paing Linn
- Industrial Property Rights Holder
  高橋智聡、河野晋、Paing Linn
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-228526
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H03576
[Patent] SUCLA2遺伝子欠失前立腺がんを特異的に死滅させる化合物2019
- Inventor(s)
  高橋智聡、河野晋、Paing Linn
- Industrial Property Rights Holder
  高橋智聡、河野晋、Paing Linn
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-228526
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K22555
[Presentation] Targeting RB1 status in cancer.2023
- Author(s)
  Takahashi C
- Organizer
  Gynecologic Oncology Symposium (Shanghai)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] The mechanism whereby PDAC resists to CDK inhibition.2023
- Author(s)
  Zhang Y, Gothwal KS, Kohno S and Takahashi C.
- Organizer
  第82回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] 2-OG代謝を標的としたRB-SUCLA2欠失前立腺がん治療法の確立2023
- Author(s)
  河野晋, 高橋智聡
- Organizer
  第82回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] KRAS阻害剤の基礎2023
- Author(s)
  高橋智聡
- Organizer
  日本放射線腫瘍学会第36回学術大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] 膵がんのCDK阻害剤耐性発現機構2023
- Author(s)
  高橋智聡
- Organizer
  第61回日本癌治療学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Application of CDK4/6 inhibition therapies to PDACs.2022
- Author(s)
  Zhang Y, Gothwal KS, Kohno S, Sheng J, Takahashi C.
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] RB欠失による脆弱性を標的とした前立腺がん治療法の探索.2022
- Author(s)
  河野晋, 曽我朋義,高橋智聡.
- Organizer
  第8回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] A mutant p53 P72R driven modulation of CXCR5-CXCL13 axis in human B cell lymphoma migration.2022
- Author(s)
  Gothwal KS, Kohno S, Sato A and Takahashi C.
- Organizer
  18th International p53 Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] A mutant p53 P72R driven modulation of CXCR5-CXCL13 axis in human B cell lymphoma-migratio.2022
- Author(s)
  Gothwal KS, Kohno S, Sato A and Takahashi C
- Organizer
  第80回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] RB欠損はERK経路の不活性化を介してMYCを不安定化させる.2022
- Author(s)
  Gong 麟祥, Dominic Chih-Cheng Voon, 高橋智聡, 河野晋.
- Organizer
  日本生化学会北陸支部第40回大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] SUCLA2遺伝子欠失前立腺がんに対するthymoquinoneの治療効果2022
- Author(s)
  河野晋, 高橋智聡
- Organizer
  第66回香料・テルペンおよび精油化学に関する討論会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] PDACに対するCdk 4/6阻害療法の応用2022
- Author(s)
  張園園, Gothwal KS, 河野晋, 盛金丹, 高橋智聡
- Organizer
  第80回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Pharmacologically targetable metabolic vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2022
- Author(s)
  Takahashi C, Linn P, MishiroK, Kunishima M, Watanabe Y and Kohno S.
- Organizer
  Mechanisms & Models of Cancer, Cold Spring Harbor Laboratory Meetings
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] RB-コレステロールによる未分化性維持機構の解明2021
- Author(s)
  9.河野晋, 佐々木信成, 高橋智聡.
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] CDK4/6 inhibitor combination therapy for the treatment of RB1-intact HCC.2021
- Author(s)
  Sheng J, Kohno S, and Takahashi C.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Treatment of RB1-intact cancers with CDK4/6 inhibitor combination therapy.2021
- Author(s)
  Sheng J, Kohno S, Okada N, Ajioka I and Takahashi C.
- Organizer
  AACR Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Pharmacologically targetable metabolic vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2021
- Author(s)
  Kohno S, Paing Linn, Soga T, Takahashi C.
- Organizer
  Keystone symposia tumor metabolism and microenvironment.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] 合成CDK4/6阻害剤による肝細胞がん治療.2021
- Author(s)
  高橋智聡, 盛金丹, 河野晋.
- Organizer
  第59回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2021
- Author(s)
  Takahashi C.
- Organizer
  Cancer Science and Targeted Therapy Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 loss.2021
- Author(s)
  Kohno S, Paing Linn, Mishiro K, Kunishima M, Watanabe Y and Takahashi C
- Organizer
  AACR Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] RB1-SUCLA2欠失による代謝脆弱性を標的とした前立腺がん治療法の開発.2021
- Author(s)
  河野晋, 高橋智聡.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] RB1がん抑制遺伝子のステータスを標的とするがん治療.2021
- Author(s)
  高橋智聡, 盛金丹, 河野晋.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] 脂肪酸伸長酵素ELOVL6の阻害によるがん制御2020
- Author(s)
  張智恒, 村中勇人, 友杉充宏, 河野晋, 高橋智聡
- Organizer
  第14回スフィンゴテラピィ研究会
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] NFYAによる糖新生促進が引き起こす腫瘍抑制効果の検討2020
- Author(s)
  岡田宣宏, 辻本剛己, 吉川清次, 高橋智聡
- Organizer
  第79回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] 進行前立腺がんにおけるRB1-SUCLA2遺伝子欠失を標的とする新規治療2020
- Author(s)
  高橋智聡, Paing Linn, 曽我朋義, 河野晋
- Organizer
  第58回日本癌治療学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22555
[Presentation] RB1-SUCLA2欠損による代謝脆弱性を標的とした前立腺がん治療法の探索2020
- Author(s)
  河野晋, Paing Linn, 曽我朋義, 高橋智聡
- Organizer
  第79回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22555
[Presentation] 脂肪酸合成制御を介したNFYAによる乳がん悪性化機構への影響2020
- Author(s)
  植木ちひろ、辻本剛己、河野晋、高橋智聡、岡田宣宏
- Organizer
  第43回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] 進行前立腺がんにおけるRB1-SUCLA2遺伝子欠失を標的とする新規治療2020
- Author(s)
  高橋智聡, Paing Linn, 曽我朋義, 河野晋
- Organizer
  第58回日本癌治療学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] RB1-SUCLA2欠損による代謝脆弱性を標的とした前立腺がん治療法の探索2020
- Author(s)
  河野晋, Paing Linn, 曽我朋義, 高橋智聡
- Organizer
  第79回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] キナーゼ阻害剤と組み合わせたCDK4/6阻害剤によるHCCの新しい併用療法2020
- Author(s)
  盛金丹, 高橋智聡, 河野晋, 岡田宣宏
- Organizer
  第43回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509
[Presentation] Pharmacologically targetable vulnerability in prostate adenocarcinoma carrying RB1-SUCLA2 deletion.2019
- Author(s)
  Paing Linn, Kohno S and Takahashi C
- Organizer
  第42回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB tumor suppressor functions in metabolic regulation.2019
- Author(s)
  Takahashi C
- Organizer
  VI International conference "Modern biotechnology for science and practice”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] リポポリサッカライドによって惹起される炎症反応に対するregucalcinの抑制効果2019
- Author(s)
  村田富保, 河野晋, 高橋智聡, 疋田清美, 金田典雄
- Organizer
  第42回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB inactivation enhances protumoral microenvironment by elevating CCL2 expression.2019
- Author(s)
  Li F, Kitajima S and Takahashi C
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB1 inactivation induces a protumoral microenvironment via enhanced CCL2 secretion.2019
- Author(s)
  Takahashi C
- Organizer
  2019 International RB Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB1 inactivation induces a protumoral microenvironment via enhanced cytokine and chemokine secretion.2019
- Author(s)
  Takahashi C
- Organizer
  第9回中国復旦大学上海がんセンタージョイントシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB1 inactivation induces a protumoral microenvironment.2019
- Author(s)
  Takahashi C
- Organizer
  International Symposium on Tumor Biology in Kanazawa 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] High Fat Diet Exposure Induces c-Myc Stabilization in Mammary Gland Epithelium.2019
- Author(s)
  Kulathunga N, Kohno S, Muranaka H and Takahashi C
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] Therapeutic Vulnerability of RB1-SUCLA2 co-deleted Prostate Cancer2019
- Author(s)
  Linn P, Kohno S and Takahashi C
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22555
[Presentation] RB1 inactivation induces a protumoral microenvironment.2019
- Author(s)
  Takahashi C
- Organizer
  世界展開力ロシア　シンポジウム（Russia-Japan Medical symposium）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] Pharmacologically targetable vulnerability in prostate adenocarcinoma carrying RB1-SUCLA2 deletion2019
- Author(s)
  Linn P, Kohno S and Takahashi C
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22555
[Presentation] STING signaling in KRAS-driven lung cancer.2019
- Author(s)
  Kitajima S, Takahashi C and Barbie DA
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] Therapeutic Vulnerability of RB1-SUCLA2 co-deleted Prostate Cancer.2019
- Author(s)
  Paing Linn, Kohno S and Takahashi C
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB controls differentiation through positive regulation of phosphoglycerate mutases2018
- Author(s)
  Kohno S and Takahashi C
- Organizer
  Abcam Cancer and Metabolism conference 2018
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling.2018
- Author(s)
  Muranaka H, Hayashi A, Minami K, Kitajima S, Kohno S, Nishimoto Y, Nagatani N, Suzuki M, Kulathunga N, Sasaki N, Okada N, Matsuzaka T, Shimano H, Tada H and Takahashi C
- Organizer
  Abcam Cancer and Metabolism conference 2018
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] RB controls undifferentiated status through positive regulation of phosphoglycerate mutases.2018
- Author(s)
  Takahashi C
- Organizer
  第13回生命医科学研究所ネットワーク国際シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] 脂肪酸伸長酵素ELOVL6のがんにおける遺伝子発現とがん促進効果の作用機序の検討2018
- Author(s)
  張智恒, 村中勇人, 高橋智聡
- Organizer
  第13回スフィンゴテラピィ研究会
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling.2018
- Author(s)
  Muranaka H and Takahashi C.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] Regulation of metabolism by RB tumor suppressor gene2017
- Author(s)
  Takahashi C.
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  Washington/USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] NFYA regulates multistep process of cancer heterogeneity formation.2017
- Author(s)
  Okada N and Takahashi C
- Organizer
  3rd International Symposium on Cell Competition. 2017年8月29日
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05615
[Presentation] Regulation of metabolism by RB tumor suppressor.2017
- Author(s)
  Takahashi C
- Organizer
  The 33rd International Symposium of Radiation Biology Center, Kyoto University
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] Metabolic regulation by RB tumor suppressor.2017
- Author(s)
  Takahashi C
- Organizer
  The 10th Commemorative Lecture of Pin-Wen Lin of Pancreatic Cancer and 2017 Cancer Biology Symposium
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] Regulation of metabolism by RB tumor suppressor gene.2017
- Author(s)
  Takahashi C
- Organizer
  AACR Annual Meeting 2017
- Data Source
  KAKENHI-PROJECT-17H03576
[Presentation] CONTROL OF GLUCOSE METABOLISM BY RB.2016
- Author(s)
  Kohno S, Takahashi C
- Organizer
  Translational research in cancer cell metabolism
- Place of Presentation
  Palacio Euskalduna Jauregia /ビルバオスペイン
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Phosphoglyceratemutases (PGAMs) mediate RB function to control differentiation.2016
- Author(s)
  Kohno S and Takahashi C.
- Organizer
  Fourth International Rb Meeting
- Place of Presentation
  Hilton Columbus Downtown /コロンバス　オハイオ州
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Metabolic regulation by RB tumor suppressor gene.2016
- Author(s)
  Takahashi C.
- Organizer
  日仏交流セミナー「癌・疾病における細胞・個体老化」
- Place of Presentation
  京都/コープイン京都
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Metabolic regulation by RB tumor suppressor gene.2016
- Author(s)
  Takahashi C.
- Organizer
  2016 International Symposium of Cancer Center of Excellence-Innovative Research in Cancer Prevention and Treatment
- Place of Presentation
  CHANG YUNG-FA FOUNDATION International Convention Center/台北
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Metabolic rewiring in Rb deficient cells during cancer progression.2016
- Author(s)
  Kohno S, Okahashi N, Kitajima S Suzuki S, Tanaka T, Matsuda F, Shimizu H and Takahashi C.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans USA/Ernest N. Morial Convention Center
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Cooperative roles of Rb and SREBP-1 in controlling fatty acid metabolism and carcinogenesis.2016
- Author(s)
  Muranaka H, Tada H, Hayashi A, Minami K, Kitajima S, Tange S, Suzuki T, Matsuzaka T, Shimano H and Takahashi C
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640070
[Presentation] RB function in controlling glycolysis.2016
- Author(s)
  Kohno S, Kitajima S and Takahashi C.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640070
[Presentation] Cooperative roles of Rb and SREBP-1 in controlling fatty acid metabolism and carcinogenesis.2016
- Author(s)
  Muranaka H, Tada H, Hayashi A, Minami K, Kitajima S, Tange S, Suzuki T, Matsuzaka T, Shimano H and Takahashi C
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Presentation] RB function in controlling glycolysis.2016
- Author(s)
  Kohno S, Kitajima S and Takahashi C.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Presentation] Cooperative roles of Rb and SREBP-1 in controlling fatty acid metabolism and carcinogenesis.2016
- Author(s)
  Muranaka H, Tada H, Hayashi A, Minami K, Kitajima S, Tange S, Suzuki T, Matsuzaka T, Shimano H and Takahashi C
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] The Metabolic Bases for Inflammatory Phenotype Associated with RB-deficiency in Mammary Cells.2016
- Author(s)
  Nishimoto Y, Kitajima S and Takahashi C
- Organizer
  Fourth International Rb Meeting
- Place of Presentation
  Hilton Columbus Downtown /コロンバス　オハイオ州
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RB function in controlling glycolysis.2016
- Author(s)
  Kohno S, Kitajima S and Takahashi C.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] The Metabolic Bases for Inflammatory Phenotype Associated with RB-deficiency in Mammary Cells2016
- Author(s)
  Nishimoto Y, Kitajima S and Takahashi C.
- Organizer
  ourth International Rb Meeting
- Place of Presentation
  Hilton Columbus Downtown /コロンバス　オハイオ州
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Presentation] Cooperative roles of Rb and SREBP-1 in controlling fatty acid metabolism and carcinogenesis.2015
- Author(s)
  Muranaka H, Tada H, Hayashi A, Minami K, Kitajima S, Tange S, Suzuki T, Matsuzaka T, Shimano H, Takahashi C.
- Organizer
  Cancer and Metabolism conference
- Place of Presentation
  英国　Cambridge/Robinson College
- Year and Date
  2015-09-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Cooperative roles of Rb and SREBP-1 in controlling fatty acid metabolism and carcinogenesis.2015
- Author(s)
  Muranaka H, Tada H, Hayashi A, Minami K, Kitajima S, Tange S, Suzuki T, Matsuzaka T, Shimano H, Takahashi C.
- Organizer
  Cancer and Metabolism conference
- Place of Presentation
  英国 Cambridge/Robinson College
- Year and Date
  2015-09-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640070
[Presentation] Metabolic functions of RB tumor suppressor in controlling undifferentiated state.2015
- Author(s)
  Takahashi C
- Organizer
  2015 the Catholic Univ. of Korea Seoul St Mary’s Hospital Comprehensive Cancer Institute International Symposium
- Place of Presentation
  韓国　ソウル　St Mary’s Hospital
- Year and Date
  2015-05-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Metabolic functions of RB tumor suppressor in controlling undifferentiated state.2015
- Author(s)
  Takahashi C
- Organizer
  2015 the Catholic Univ. of Korea Seoul St Mary’s Hospital Comprehensive Cancer Institute International Symposium
- Place of Presentation
  韓国ソウル St Mary’s Hospital
- Year and Date
  2015-05-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640070
[Presentation] Cooperative roles of Rb and SREBP-1 in controlling fatty acid metabolism and carcinogenesis.2015
- Author(s)
  Muranaka H, Tada H, Hayashi A, Minami K, Kitajima S, Tange S, Suzuki T, Matsuzaka T, Shimano H, Takahashi C.
- Organizer
  Cancer and Metabolism conference
- Place of Presentation
  英国 Cambridge/Robinson College
- Year and Date
  2015-09-29
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Presentation] The metabolic function of RB in controlling mevalonate (MVA) pathway regulates tumor progression2015
- Author(s)
  Sasaki N, Kitajima S, Muranaka H, Shamma A, Kohno S, Takahashi C
- Organizer
  Keystone Symposia
- Place of Presentation
  Vancouver・Canada・Fairmont Hotel
- Year and Date
  2015-01-16
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Metabolic functions of RB tumor suppressor in controlling undifferentiated state.2015
- Author(s)
  Takahashi C
- Organizer
  2015 the Catholic Univ. of Korea Seoul St Mary’s Hospital Comprehensive Cancer Institute International Symposium
- Place of Presentation
  韓国ソウル St Mary’s Hospital
- Year and Date
  2015-05-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487
[Presentation] The metabolic function of RB in controlling mevalonate (MVA) pathway and tumor progression.2014
- Author(s)
  Sasaki N, Muranaka H, Kitajima S, Kohno S, Shamma A and Takahashi C
- Organizer
  第37回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RB functions in rewiring metabolic pathways in cancer cells2014
- Author(s)
  Chiaki Takahashi
- Organizer
  熊本大学HIGOプログラム最先端研究セミナー
- Place of Presentation
  熊本県・熊本市・熊本大学発生研
- Year and Date
  2014-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] がん幹細胞と代謝- RBがん抑制遺伝子研究からのアプローチ2014
- Author(s)
  高橋智聡
- Organizer
  第1３回福井臨床薬理を考える会
- Place of Presentation
  福井県・福井市・ユアーズホテル
- Year and Date
  2014-11-10
- Invited
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] IL-6-dependent inflammatory phenotype induced by RB inactivation sustains self-renewal and drug resistance.2014
- Author(s)
  Kitajima S, and Takahashi C
- Organizer
  がん微小環境に関する国際シンポジウム
- Place of Presentation
  石川県・金沢市・金沢大学
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-26640070
[Presentation] Reductive glutamine metabolism in p53-null soft tissue sarcoma cells.2014
- Author(s)
  Okahashi N, Matsuda F, Kohno S, Takahashi C and Shimizu H.
- Organizer
  Metabolomics 2014.
- Place of Presentation
  山形県・鶴岡市・慶応大学鶴岡キャンパス
- Year and Date
  2014-06-05
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] ATM regulates DNMT1 protein stability and coordinates its acetylation-driven ubiquitination during Rb loss-induced carcinogenesis Gordon Conference2012
- Author(s)
  Shamma A., Kido Y., Sasaki N., Takahashi C
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] Epigenetic function of retinoblastoma protein entails functional association of ATM and DNMT12012
- Author(s)
  Shamma A., Sasaki N., Takahashi C
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育文化会館、札幌市
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] ATM regulates DNMT1 protein stability and coordinates its acetylation-driven ubiquitination during Rb loss-induced carcinogenesis2012
- Author(s)
  A.Shamma, Y.Kido, N.Sasaki, C.Takahashi
- Organizer
  Gordon Conference (DNA Damage, Mutation & Cancer)
- Place of Presentation
  Ventura Beach Marriott(アメリカ)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] DNMT1 Links DNA Damage Response and Cellular Senescence during Rb deficiency-induced Tumorigenesis2011
- Author(s)
  Shamma A., Takahashi C
- Organizer
  第70回日本癌学会学術総会(招待講演)
- Place of Presentation
  名古屋国際会議場、愛知県
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] DNMT1 Links DNA Damage Response and Cellular Senescence during Rb deficiency-induced Tumorigenesis2011
- Author(s)
  A.Shamma, C.Takahashi
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] RB-RAS経路とがんの悪性進展2010
- Author(s)
  高橋智聡
- Organizer
  第3回SYMPHONY
- Place of Presentation
  ホテルメトロポリタン・エドモンド(東京都) 招待講演
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] The Rb-Ras pathway in malignant progression.2010
- Author(s)
  Takahashi C, Shamma A.
- Organizer
  International Cancer Biology Symposium at National Sun Yat-Sen University
- Place of Presentation
  国立中山大学(Taiwan) 招待講演
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] The Rb-Ras pathway in malignant progression2010
- Author(s)
  C. Takahashi.
- Organizer
  National Sun Yat-Sen University International Cancer Biology Symposium
- Place of Presentation
  National Sun Yat-Sen University (Taiwan)
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] ATM mediates the Rb loss-induced DNA damage response andsenescence through chromatin remodeling and pl61nk4aregulation.2010
- Author(s)
  A.Shamma , C.Takahashi.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)((招待講演))
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] The Rb-Ras pathway in malignant progression.2010
- Author(s)
  C.Takahashi , A.Shamma.
- Organizer
  国際がん生物学シンポジウム
- Place of Presentation
  国立中山大学(台湾)
- Year and Date
  2010-06-28
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] ATM mediates the Rb loss-induced DNA damage response and senescence through chromatin remodeling and p16Ink4a regulation2010
- Author(s)
  Shamma A., Takahashi C
- Organizer
  第69回日本癌学会学術総会(招待講演)
- Place of Presentation
  大阪国際会議場、大阪)
- Data Source
  KAKENHI-PROJECT-22500998
[Presentation] ATM mediates the Rb-loss-induced DNA damage response and cellular senescence through chromatin remodeling and p161nk4a regulation.2010
- Author(s)
  Shamma A, Takahashi C.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] The genetic interaction of Rb and ras unveiled by the study of compound knockout mice2009
- Author(s)
  C.Takahashi, Yujiro Takegami, Takao Miki, Shunsuke Kitajima, A.Shamma
- Organizer
  日本生化学会大会シンポジウム
- Place of Presentation
  神戸国際会議場(兵庫)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] The function and mechanism of pRb-N-Ras pathway in metastatic conversion of neuroendocrine thyroid tumor.2009
- Author(s)
  C.Takahashi, A.Shamma
- Organizer
  Korean Society for Biochemistry and Molecular Biology (KSBMB)シンポジウム
- Place of Presentation
  COEX (Seoul, Korea)
- Year and Date
  2009-05-13
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] Regulation of Notch signaling and its polarity mediated by ectodomain shedding of DSL ligands.2009
- Author(s)
  C.Takahashi, T.Muraguchi, Y.Takegami, T.Miki.
- Organizer
  日本癌学会総会シンポジウム
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] Critical role of cellular senescence mediated by N-Ras isoprenylation in suppressing Rb-deficient C-cell carcinogenesis2009
- Author(s)
  A.Shamma, C.Takahashi
- Organizer
  日本癌学会総会
- Place of Presentation
  パシフィコ横浜 (神奈川)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] The function and mechanism of pRb-N-Ras pathway in metastatic conversion of neuroendocrine thyroid tumor2009
- Author(s)
  C.Takahashi, A.Shamma
- Organizer
  Korean Society for Biochemistry and Molecular Bidogy (KSBMB) シンポジウム
- Place of Presentation
  COEX (Seoul, Korea)
- Year and Date
  2009-05-13
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] The genetic interaction of Rb and ras in the multi-step carcinogenesis model2009
- Author(s)
  C. Takahashi, A. Shamma
- Organizer
  癌学会総会シンポジウム
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] The genetic interaction of Rb and ras unveiled by the study of compound knockout mice2009
- Author(s)
  C.Takahashi, Yujiro Takegami, Takao Miki, Shunsuke Kitajima, A.Shamma
- Organizer
  日本生化学会大会シンポジウム
- Place of Presentation
  神戸国際会議場 (兵庫)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] RECK regulates p53-p21-dependent cellular senescence in mouse embryonic fibroblasts2009
- Author(s)
  S.Kitajima, T.Miki, C.Takahashi
- Organizer
  日本分子生物学会年会ポスター発表
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECK regulates p53-p21-dependent cellular senescence in mouse embryonic fibroblasts2009
- Author(s)
  北嶋俊輔, 三木高雄, 高橋智聡
- Organizer
  日本分子生物学会年会ポスター発表
- Place of Presentation
  パシフィコ横浜 (神奈川)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] Regulation of Notch signaling and its polarity mediated by ectodomain shedding of DSL ligands2009
- Author(s)
  C.Takahashi, T.Muraguchi, Y.Takegami, T.Miki
- Organizer
  日本癌学会総会シンポジウム
- Place of Presentation
  パシフィコ横浜 (神奈川)(口頭発表)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] Critical role of cellular senescence mediated by N-Ras isoprenylation in suppressing Rb-deficient C-cell carcinogenesis2009
- Author(s)
  A.Shamma, C.Takahashi
- Organizer
  日本癌学会総会口頭発表
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECKによるp21CIP1依存的な細胞増殖・細胞老化の制御2009
- Author(s)
  北嶋俊輔, 三木高雄, 高橋智聡
- Organizer
  日本病態プロテアーゼ学会ポスター発表
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] The genetic interaction of Rb and ras unveiled by the study of compound knockout mice.2009
- Author(s)
  C. Takahashi, Y. Takegami, T. Miki, S. Kitajima, A. Shamma
- Organizer
  日本生化学会大会シンポジウム
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] Critical role of cellular senescence mediated by N-Ras isoprenylation in suppressing Rb-deficient C-cell carcinogenesis2009
- Author(s)
  A. Shamma, C. Takahashi
- Organizer
  日本癌学会総会口頭発表
- Place of Presentation
  神戸国際会議場(兵庫)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECKによるp21CIP1依存的な細胞増殖・細胞老化の制御2009
- Author(s)
  北嶋俊輔、三木高雄、高橋智聡
- Organizer
  日本病態プロアテーゼ学会ボスター発表
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] The function and mechanism of pRb-N-Ras pathway in metastatic conversion of neuroendocrine thyroid tumor2009
- Author(s)
  C. Takahashi, A. Shamma
- Organizer
  Korean Society for Biochemistry and Molecular Biology (KSBMB)シンポジウム
- Place of Presentation
  COEX (Korea)
- Year and Date
  2009-05-13
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECKによるp21CIP1依存的な細胞増殖・細胞老化の制御2009
- Author(s)
  北嶋俊輔, 三木高雄, 高橋智聡
- Organizer
  日本病態プロテアーゼ学会ポスター発表
- Place of Presentation
  千里ライフサイエンスセンター (大阪)
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-21390093
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102008
- Author(s)
  T. Muraguchi, Y. Takegami, T. Miki, S. Kitajima, C. Takahashi
- Organizer
  細胞生物学会ミニシンポジウム
- Place of Presentation
  横浜・みなとみらい
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102008
- Author(s)
  T. Muraguchi, Y. Takegami, T. Miki, S. Kitajima, C. Takahashi
- Organizer
  細胞生物学会ミニシンポジウム
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECKによる膜結合型メタロプロテアーゼ群の制御2008
- Author(s)
  高橋智聡, 三木貴雄, 村口輝行, 竹上雄治郎, 北嶋俊輔
- Organizer
  日本分子生物学会・生化学学会合同年会BMB2008シンポジウム
- Place of Presentation
  神戸・ポートピアアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] RECKによる膜結合型メタロプロテアーゼ群の制御2008
- Author(s)
  高橋智聡, 三木貴雄, 村口輝行, 竹上雄治郎, 北嶋俊輔
- Organizer
  日本分子生物学会・生化学学会合同年会BMB2008シンポジウム
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECKによる膜結合型メタロプロテアーゼ群の制御2008
- Author(s)
  高橋智聡、三木貴雄、村口輝行、竹上雄治郎、北嶋俊輔
- Organizer
  日本分子生物学会・生化学学会合同年会BMB2008シンポジウム
- Place of Presentation
  神戸・ポートビアアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] RECK .regulates Notch signaling during cortical development by directly interacting with ADAM102008
- Author(s)
  T. Muraguchi, Y. Takegami, T. Miki, S. Kitajima and C. Takahashi
- Organizer
  細胞生物学会ミニシンポジウム
- Place of Presentation
  横浜・みなとみらい
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20012027
[Presentation] GPIアンカー型糖蛋白質RECKによる膜結合型メタロプロテアーゼ制御の様式と生物学的作用2007
- Author(s)
  三木貴雄、北嶋俊輔、竹上雄治郎、村口輝行、高橋智聡*
- Organizer
  日本分子生物学会・生化学会総会ワークショップ
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] Analysis of tumor progression and metastasis using genetically modified mice2007
- Author(s)
  C., Takahashi
- Organizer
  COE International Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2007-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] RbとN-rasの遺伝学的関係とがん化2007
- Author(s)
  高橋智聡
- Organizer
  文部科学省がん特定研究班5領域合同シンポジウム
- Place of Presentation
  東京、経団連会館
- Year and Date
  2007-02-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] GPIアンカー型糖蛋白質RECKによる膜結合型メタロプロテアーゼ制御の様式と生物学的作用2007
- Author(s)
  三木貴雄、北嶋俊輔、竹上雄治郎、村口輝行、高橋智聡*
- Organizer
  日本分子生物学会・生化学会総会ワークショップ
- Place of Presentation
  横浜、パシフイコ横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-18012025
[Presentation] The genetic interaction of Rb and N-ras during carcinogenesis2007
- Author(s)
  C., Takahashi
- Organizer
  ymposium by Grant-in-aid for Priority A eas
- Place of Presentation
  Tokyo
- Year and Date
  2007-02-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] RbとN-rasの遺伝学的関係とがん化2007
- Author(s)
  高橋智聡
- Organizer
  文部科学省がん特定研究班5領域合同シンポジウム
- Place of Presentation
  東京、経団連会館
- Year and Date
  2007-02-23
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] ADAM10阻害因子RECKによるNotchシグナル伝達系制御2007
- Author(s)
  高橋智聡
- Organizer
  病態と治療におけるプロテアーゼとインヒビター学会シンポジウム
- Place of Presentation
  大阪、千里ライフサイエンスセンター
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18012025
[Presentation] The Biological Role of RECK and Its Mechanism2007
- Author(s)
  C. Takahashi
- Organizer
  National Sun Yat-Sen University International Cancer Biology Symposium
- Place of Presentation
  Kaohsiung, Taiwan
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] RbとN-rasの遺伝学的関係とがん化2007
- Author(s)
  高橋智聡
- Organizer
  文部科学省がん特定研究班5領域合同シンポジウム
- Place of Presentation
  東京、経団連会館
- Year and Date
  2007-02-23
- Data Source
  KAKENHI-PROJECT-18012025
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102007
- Author(s)
  T. Muraguchi, Y. Takegami and C. Takahashi*
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens, Greece
- Year and Date
  2007-09-24
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] Analysis of tumor progression and metastasis using genetically modified mice2007
- Author(s)
  高橋智聡
- Organizer
  21世紀COEプログラム「病態解明を目指す基礎医学研究拠点」平成19年度COE国際シンポジウム
- Place of Presentation
  京都、京都大学
- Year and Date
  2007-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] The Biological Role of RECK and Its Mechanism2007
- Author(s)
  C. Takahashi
- Organizer
  National Sun Yat-Sen University International Cancer Biology Symposium
- Place of Presentation
  Kaohsiung, Taiwan
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102007
- Author(s)
  T. Muraguchi, Y. Takegami and C. Takahashi*
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens, Greece
- Year and Date
  2007-09-24
- Data Source
  KAKENHI-PROJECT-18012025
[Presentation] The Biological Role of RECK and Its Mechanism2007
- Author(s)
  C., Takahashi
- Organizer
  National Sun Yat-Sen University Inernational Cancer Biology Symposium
- Place of Presentation
  Kaohsiung, Taiwan
- Year and Date
  2007-06-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] GPIアンカー型糖蛋白質RECKによる膜結合型メタロプロテアーゼ制御の様式と生物学的作用2007
- Author(s)
  三木貴雄、北嶋俊輔、竹上雄治郎、村口輝行、高橋智聡*
- Organizer
  日本分子生物学会・生化学会総会ワークショップ
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2007-12-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] Regulation of Notch signaling by an ADAM10 inhibitor RECK2007
- Author(s)
  C., Takahashi
- Organizer
  ICPIPT meeting
- Place of Presentation
  Osaka
- Year and Date
  2007-08-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102007
- Author(s)
  T. Muraguchi, Y. Takegami and C. Takahashi*
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens, Greece(アテネ、ギリシア)
- Year and Date
  2007-09-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102007
- Author(s)
  T., Muraguchi, Y., Takegami, C, Takahashi
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens,Greece
- Year and Date
  2007-09-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] ADAM10阻害因子RECK によるNotchシグナル伝達系制御2007
- Author(s)
  高橋智聡
- Organizer
  病態と治療におけるプロテアーゼとインヒビター学会シンポジウム
- Place of Presentation
  大阪、千里ライフサイエンスセンター
- Year and Date
  2007-08-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] The Biological Role of RECK and Its Mechanism2007
- Author(s)
  C. Takahashi
- Organizer
  National Sun Yat-Sen University International Cancer Biology Symposium
- Place of Presentation
  Kaohsiung, Taiwan
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-18012025
[Presentation] ADAM10阻害因子RECKによるNotchシグナル伝達系制御2007
- Author(s)
  高橋智聡
- Organizer
  病態と治療におけるプロテアーゼとインヒビター学会シンポジウム
- Place of Presentation
  大阪、千里ライフサイエンスセンター
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] Analysis of tumor progression and metastasis using genetically modifiedmice2007
- Author(s)
  高橋智聡
- Organizer
  21世紀COEプログラム「病態解明を目指す基礎医学研究拠点」平成19年度COE国際シンポジウム
- Place of Presentation
  京都、京都大学
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18012025
[Presentation] The Biological Role of RECK and Its Mechanism2007
- Author(s)
  C. Takahashi
- Organizer
  National Sun Yat-Sen University International Cancer Biology Symposium
- Place of Presentation
  Kaohsiung, Taiwan(高雄、台湾)
- Year and Date
  2007-06-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] ADAM10阻害因子RECK によるNotchシグナル伝達系制御2007
- Author(s)
  高橋智聡
- Organizer
  病態と治療におけるプロテアーゼとインヒビター学会シンポジウム
- Place of Presentation
  大阪、千里ライフサイエンスセンター
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] RECK regulates Notch signaling during cortical development by directly interacting with ADAM102007
- Author(s)
  T. Muraguchi, Y. Takegami and C. Takahashi*
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens, Greece
- Year and Date
  2007-09-24
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] Analysis of tumor progression and metastasis using genetically modified mice2007
- Author(s)
  高橋智聡
- Organizer
  21世紀COEプログラム「病態解明を目指す基礎医学研究拠点」平成19年度COE国際シンポジウム
- Place of Presentation
  京都、京都大学
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18659085
[Presentation] N-ms functions as a tumor suppressor in human and mouse medullary thyroid carcinoma2006
- Author(s)
  C., Takahashi
- Organizer
  Workshop on Immunology, Cancer, and Aging
- Place of Presentation
  Kyoto
- Year and Date
  2006-02-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] RECKの作用メカニズムと幹細胞能を維持する細胞外環境形成への寄与2006
- Author(s)
  高橋智聡
- Organizer
  日本分子生物学会フォーラムシンポジウム
- Place of Presentation
  名古屋、国際会議場
- Year and Date
  2006-12-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] The mechanism of RECK function and its contribution to the extracellular milieu supporting stem cell activities2006
- Author(s)
  C., Takahashi
- Organizer
  MBSJ 2006 Forum
- Place of Presentation
  Nagoya
- Year and Date
  2006-12-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390101
[Presentation] N-ras functions as a tumor suppressor in human and mouse medullary thyroid carcinoma2006
- Author(s)
  C. Takahashi
- Organizer
  Workshop on Immunology, Cancer, and Aging
- Place of Presentation
  京都、京都大学
- Year and Date
  2006-02-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390101

1. SHAMMA Awad (50402839)

# of Collaborated Projects: 5 results

# of Collaborated Products: 28 results
2. Kohno Susumu (30625463)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. Kitajima Syunsuke (90566465)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. 野田亮 (30146708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Hayashi Naoyuki (50253456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. Sasaki Nobunari (40415170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. Tanaka Masao (10332719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 糸原重美 (60252524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋雅英 (40183446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岩永剛 (70378660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 杉本直俊 (80272954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 村田富保 (80285189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 寺前純吾 (90351395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 橋本和宜 (10816242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HORIKE Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. BABA Tomohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. Mukaida Naofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. TSUCHIYA Kohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡田宣宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 笠原敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 田所優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 平田多佳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 平尾敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 町田雪乃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Chiaki 高橋 智聡

TAKAHASHI Chiaki 高橋 智聡

高橋 智聡 タカハシ チアキ

Research Projects

Research Products

Co-Researchers

レギュカルチンの多機能性を基軸とした疾患発症メカニズムの解明と疾患治療法の開発

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RB1 tumor suppressor functions in metabolismPrincipal Investigator

Principal Investigator

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Analysis of DIP2C as a novel regulator for epithelial-mesenchymal transition of rheumatoid arthritis synovium and a potential therapeutic target

Principal Investigator

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Drug development targeting metabolic vulnerability associated with SUCLA2 lossPrincipal Investigator

Principal Investigator

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Drug discovery based on collateral lethalityPrincipal Investigator

Principal Investigator

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RB mosaicism and cell competition in mammary epithelial and cancer cellsPrincipal Investigator

Principal Investigator

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Metabolic regulation by RB tumor suppressor genePrincipal Investigator

Principal Investigator

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細胞競合を介したがん幹細胞クローン維持機構Principal Investigator

Principal Investigator

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Research Institution

Regulation of metabolism by RB tumor suppressor genePrincipal Investigator

Principal Investigator

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Inflammatory circuit that triggres malignant progressionPrincipal Investigator

Principal Investigator

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The role of Rb-Ras pathway in cancer stem cells

Principal Investigator

Project Period (FY)

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Rbがん抑制遺伝子欠損によって誘導される蛋白質高イソプレニル化の研究Principal Investigator

Principal Investigator

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Research Institution

Analysis of cellular signals toward carcinogenesis and metastasis using genetically modified micePrincipal Investigator

Principal Investigator

Takahashi Chiaki 高橋智聡

TAKAHASHI Chiaki 高橋智聡

高橋智聡タカハシチアキ

[Book] 生体の科学　がん細胞の中の多様性・多層性2016

[Book] 生体の科学　がん細胞の中の多様性・多層性2016

[Book] 生体の科学　がん細胞の中の多様性・多層性2016