TEZUKA Tohru 手塚徹

Researcher Number	50312319
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定講師
Affiliation (based on the past Project Information) *help	2025: 京都大学, 医学研究科, 特定講師 2022: 京都大学, 医学研究科, 特定講師 2018 – 2021: 京都大学, スーパーグローバルコース医学生命系ユニット, 特定講師 2020: 東京大学, 医科学研究所, 助教 2009 – 2017: The University of Tokyo, 医科学研究所, 助教 2007: Tokyo Medical and Dental University, 難治疾患研究所, 特任講師 2000 – 2006: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / Basic Section 56010:Neurosurgery-related / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Complex systems / Functional biochemistry Except Principal Investigator General medical chemistry / Basic Section 56010:Neurosurgery-related / Complex systems / Biological Sciences
Keywords	Principal Investigator シグナル伝達 / チロシンリン酸化 / Src / 神経筋接合部 / 神経科学 / チロシンキナーゼ / 脳・神経 / NMDA受容体 / Cbl / tyrosine phosphorylation … More / 神経筋シナプス / 神経筋疾患 / 遺伝子 / リン酸化 / 記憶・学習 / ユビキチン化 / 細胞内シグナル / 血管閉塞 / 血管閉塞性疾患 / RNF213 / もやもや病 / Neuroscience / Nervous System / ユビキチン / 神経系 / DNA Chip Analysis / Knock-in Mice / NMDA receptor / ノックインマウス / Fyn / NR2B / NR2A / DNAチップ解析 / 遺伝子改変マウス / 筋無力症 / 蛋白質リン酸化 / 行動学 / 蛋白質 / NMDA 受容体 / Cb1 / PSD-95 / 転写標的遺伝子 / 標的基質 / マイクロアレイ / 脳神経 / DT40 … More Except Principal Investigator 神経科学 / シグナル伝達 / 神経筋シナプス / 細胞内シグナル伝達 / stem cell / genetics / atherosclerosis / inflammation / moyamoya / 運動機能障害 / 血管閉塞性病変 / R4810K変異 / 脳卒中 / 循環器疾患 / AAA+ / E3 ligase / ウイルス抗体の保有状況 / Mitotic failure / Arterial-Stenosis / RNF213-R4810K / 腸内細菌 / 細胞分裂 / R4810K / Apoptosis / ER stress / RNF213 / シグナル制御 / 感受性遺伝子 / もやもや病 / 遺伝疫学 / Wnt5a-Rorシグナル / 頂底極性シグナル / 繊毛関連症候群 / 癌の浸潤転移 / 上皮間葉転換 / エピジェネティック制御 / 癌の浸潤 / 繊毛関連症候群・炎症 / 上皮管腔組織の破綻 / 線毛シグナル / 組織炎症 / 上皮管腔組織形成 / 癌の浸潤・進展 / アダプター分子 / 非古典的Wntシグナル / 繊毛シグナル / 平面細胞極性シグナル / 上皮管腔組織破綻 Less

Elucidation of the molecular mechanisms underlying type 2 inflammation in moyamoya disease.
- Principal Investigator
  
  峰晴陽平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Functional analysis of heritable risk factors for moyamoya disease and strokePrincipal Investigator
- Principal Investigator
  
  Tezuka Tohru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular society
- Principal Investigator
  
  Koizumi Akio
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Signaling in NMJ formation and its synaptopathy
- Principal Investigator
  
  Yamanashi Yuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Develpment of a new method to treat neuromuscular diseasesPrincipal Investigator
- Principal Investigator
  
  Tezuka Tohru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
Molecular mechanisms of the formation and maintenance of NMJsPrincipal Investigator
- Principal Investigator
  
  TEZUKA Tohru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
細胞内リガンドによる受容体型チロシンキナーゼの活性化機構Principal Investigator
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Dysfunction of planar cell polarity signaling and its relationship with ciliopathies and cancer invasion and metastasis
- Principal Investigator
  
  MINAMI YASUHIRO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Molecular signaling in neuromuscular synaptogenesis and myasthenia
- Principal Investigator
  
  YAMANASHI Yuji
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Roles of Dok-7 and MuSK in neuromuscular synaptogenesisPrincipal Investigator
- Principal Investigator
  
  TEZUKA Tohru
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Src及びCblファミリーによるチロシンリン酸化シグナルの正負の制御と脳高次機能Principal Investigator
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
  The University of Tokyo
Src及びCblファミリーによるチロシンキナーゼシグナルの正負の制御と脳高次機能Principal Investigator
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidation of roles of Cbl-family proteins in the nervous system.Principal Investigator
- Principal Investigator
  
  TEZUKA Tohru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
Src及びCblファミリーによるチロシンキナーゼシグナルの正負の制御と脳高次機能Principal Investigator
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidation of NMDAR tyrosine phosphorylation by Src.Principal Investigator
- Principal Investigator
  
  TEZUKA Tohru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
神経系におけるSrc型チロシンキナーゼの新規標的基質・遺伝子群の同定及び機能解析Principal Investigator
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
蛋白質分解を介してチロシンキナーゼシグナルを抑制するCblファミリーの機能解析Principal Investigator
- Principal Investigator
  
  手塚徹
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2011 2010 2009 2007 Other

All Journal Article Presentation Book

[Book] 生体の科学Vol.62 No.22011
- Author(s)
  手塚徹
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21790266
[Book] 生体の科学(先天性筋無力症の分子基盤、Vol.62 No.2)2011
- Author(s)
  手塚徹、山梨裕司
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21790266
[Book] Cbl Proteins, Editor: Alex Tsygankov,
- Author(s)
  Tezuka, T., 他
- Publisher
  NOVA Publishers(未定)(in press)
- Data Source
  KAKENHI-PROJECT-18022013
[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFκB activation and apoptosis in an AAA+ domain-dependent manner2020
- Author(s)
  Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Issue: 3 Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-20H03790
[Journal Article] Overexpression of Dok-7 in skeletal muscle enhances neuromuscular transmission with structural alterations of neuromuscular junctions: Implications in robustness of neuromuscular transmission2020
- Author(s)
  Eguchi T, Tezuka T, Fukudome T, Watanabe Y, Sagara H, Yamanashi Y
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 523 Issue: 1 Pages: 214-219
- DOI
  10.1016/j.bbrc.2019.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01532
[Journal Article] The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation2017
- Author(s)
  Ryo Ueta, Tohru Tezuka, Yosuke Izawa, Sadanori Miyoshi, Satoru Nagatoishi, Kouhei Tsumoto, Yuji Yamanashi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 161 Pages: 269-277
- DOI
  10.1093/jb/mvw073
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J08885, KAKENHI-PROJECT-16K14575, KAKENHI-PROJECT-15K18500
[Journal Article] DOK7　gene therapy enhances motor activity and life span in ALS model mice2017
- Author(s)
  Miyoshi Sadanori、Tezuka Tohru、Arimura Sumimasa、Tomono Taro、Okada Takashi、Yamanashi Yuji
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 9 Issue: 7 Pages: 880-889
- DOI
  10.15252/emmm.201607298
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293328, KAKENHI-PROJECT-16K14575
[Journal Article] Postnatal knockdown of dok-7 gene expression in mice causes structural defects in neuromuscular synapses and myasthenic pathology2016
- Author(s)
  Eguchi T, Tezuka T, Miyoshi S, and Yamanashi Y
- Journal Title
  
  Genes to Cells
  
  Volume: 印刷中 Issue: 6 Pages: 670-676
- DOI
  10.1111/gtc.12370
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-25117708, KAKENHI-PROJECT-25460357, KAKENHI-PROJECT-14J08885, KAKENHI-PROJECT-16K14575
[Journal Article] DOK7 gene therapy benefits mouse models of diseases characterized by defects in the neuromuscular junction2014
- Author(s)
  Sumimasa Arimura, Takashi Okada, Tohru Tezuka, Tomoko Chiyo, Yuko Kasahara, Toshiro Yoshimura, Masakatsu Motomura, Nobuaki Yoshida, David Beeson, Shin’ichi Takeda, Yuji Yamanashi
- Journal Title
  
  Science
  
  Volume: 345 Issue: 6203 Pages: 1505-1508
- DOI
  10.1126/science.1250744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249013, KAKENHI-PROJECT-24500472, KAKENHI-PUBLICLY-25110711, KAKENHI-PROJECT-25460357, KAKENHI-PROJECT-25461318, KAKENHI-PROJECT-26293328, KAKENHI-PROJECT-26461302, KAKENHI-PROJECT-26860273
[Journal Article] The MuSK-activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses2014
- Author(s)
  Tohru Tezuka, Akane Inoue, Taisuke Hoshi, Scott D. Weatherbee, Robert W. Burgess, Ryo Ueta, and Yuji Yamanashi
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Issue: 46 Pages: 16556-16561
- DOI
  10.1073/pnas.1408409111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249013, KAKENHI-PUBLICLY-25110711, KAKENHI-PROJECT-25460357
[Journal Article] Protocadherin 17 regulates presynaptic assembly in topographic corticobasal ganglia circuits2013
- Author(s)
  Hoshina N, Tanimura A, Yamasaki M, Inoue T, Fukabori R, Kuroda T, Yokoyama K, Tezuka T, Sagara H, Hirano S, Kiyonari H, Takada M, Kobayashi K, Watanabe M, Kano M, Nakazawa T, Yamamoto T
- Journal Title
  
  Neuron
  
  Volume: 78 Issue: 5 Pages: 839
- DOI
  10.1016/j.neuron.2013.03.031
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115006, KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23300119, KAKENHI-PROJECT-23700411, KAKENHI-PUBLICLY-24121705, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-24790187, KAKENHI-PROJECT-25000015, KAKENHI-PUBLICLY-25110716, KAKENHI-PROJECT-25250003, KAKENHI-PROJECT-25430037, KAKENHI-PROJECT-25460357, KAKENHI-PROJECT-25640011, KAKENHI-PROJECT-25640033
[Journal Article] An adaptor protein complex of FRS2beta and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation2013
- Author(s)
  後藤　典子
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 3 Pages: 345-352
- DOI
  10.1111/cas.12086
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23510261, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PUBLICLY-24121705, KAKENHI-PROJECT-24700968, KAKENHI-PROJECT-25460357
[Journal Article] Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic differentiation in myotubes.2013
- Author(s)
  Hoshi T, Tezuka T, Yokoyama K, Iemura S-I, Natsume T, and Yamanashi Y
- Journal Title
  
  FEBS Lett.
  
  Volume: 587 Issue: 23 Pages: 3749-3754
- DOI
  10.1016/j.febslet.2013.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117511, KAKENHI-PROJECT-23249013, KAKENHI-PLANNED-24115007, KAKENHI-PUBLICLY-24121705, KAKENHI-PUBLICLY-25110711, KAKENHI-PUBLICLY-25117708, KAKENHI-PROJECT-25460357
[Journal Article] NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala.2010
- Author(s)
  Delawary M, Tezuka T, Kiyama Y, Yokoyama K, Inoue T, Hattori S, Hashimoto R, Umemori H, Manabe T, Yamamoto T, Nakazawa T.
- Journal Title
  
  Mol Brain. 3
  
  Pages: 37-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790266
[Journal Article] Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour.2009
- Author(s)
  Taniguchi S, Nakazawa T, Tanimura A, Kiyama Y, Tezuka T, Watabe AM, Katayama N, Yokoyama K, Inoue T, Izumi-Nakaseko H, Kakuta S, Sudo K, Iwakura Y, Umemori H, Inoue T, Murphy NP, Hashimoto K, Kano M, Manabe T, Yamamoto T.
- Journal Title
  
  EMBO J. 28(23)
  
  Pages: 3717-3729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790266
[Journal Article] The roles of Dok family adapters in immunoreceptor signaling.2009
- Author(s)
  Mashima R, Hishida Y, Tezuka T, Yamanashi Y.
- Journal Title
  
  Immunol Rev. 232(1)
  
  Pages: 273-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790266
[Presentation] もやもや病患者のiPS細胞由来内皮細胞におけるRNF213変異の影響2022
- Author(s)
  尾市雄輝、峰晴陽平、吉岡美樹、手塚徹、Kuan-Chun Lan、藤渕航、香川晴信、松本智子、Knut Woltjen、小泉昭夫、宮本享、山下潤、Shohab Youssefian
- Organizer
  STROKE 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病の疾患モデルiPS細胞に対する遺伝子修復の効果2022
- Author(s)
  尾市雄輝、峰晴陽平、吉岡美樹、手塚徹、Kuan-Chun Lan、藤渕航、香川晴信、松本智子、Knut Woltjen、小泉昭夫、宮本享、山下潤、Shohab Youssefian
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] Effect of RNF213 suppression on endoplasmic reticulum stress2022
- Author(s)
  Ahmed Sharif, 小林果, 土生敏行, 原田浩二 , 手塚徹, Youssefian Shohab, 及川伸二, 村田真理子, 小泉昭夫
- Organizer
  第92回　日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] もやもや病患者のiPS細胞由来内皮細胞におけるRNF213変異の影響2022
- Author(s)
  尾市雄輝、峰晴陽平、吉岡美樹、手塚徹、Lan Kuan-Chun、藤渕航、香川晴信、松本智子、Woltjen Knut、小泉昭夫、宮本享、山下潤、Youssefian Shohab
- Organizer
  STROKE 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] Effect of RNF213 suppression on endoplasmic reticulum stress2022
- Author(s)
  Sharif Ahmed, 小林果, 土生敏行, 原田浩二 , 手塚徹, Shohab Youssefian, 及川伸二, 村田真理子, 小泉昭夫
- Organizer
  第92回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213における結合蛋白質の制御機構の解明2021
- Author(s)
  崔廷米、手塚徹、小林果、原田浩二、小泉昭夫、Youssefian Shohab
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03790
[Presentation] もやもや病感受性遺伝子産物RNF213における結合蛋白質の制御機構の解明2021
- Author(s)
  崔廷米、手塚徹、小林果、原田浩二、小泉昭夫、Youssefian Shohab
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213 の結合蛋白質の同定2020
- Author(s)
  崔　廷米、武田　美都里、小林　果、手塚　徹、原田　浩二、小泉　昭夫、Youssefian Shohab
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子RNF213の結合分子の同定2019
- Author(s)
  崔廷米, 井上令一, 武田美都里, 小林果, 手塚徹, 原田浩二, 小泉昭夫, Youssefian Shohab
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] もやもや病感受性遺伝子産物RNF213のユビキチンリガーゼ活性の検討2019
- Author(s)
  武田美都里, 手塚徹, 金びん秀, 西出旭, 崔廷米, 原田浩二, 小泉昭夫, ショハブ・ユーセフィアン
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06397
[Presentation] 神経筋接合部の形成増強による筋萎縮性側索硬化症（ALS）マウスの病態改善と延命2017
- Author(s)
  三好貞徳、手塚徹、有村純暢、伴野太郎、岡田尚巳、山梨裕司
- Organizer
  日本筋学会
- Data Source
  KAKENHI-PROJECT-16K14575
[Presentation] 生後のNMJの維持におけるDok-7の役割2016
- Author(s)
  江口貴大、手塚徹、三好貞徳、山梨裕司
- Organizer
  第２回日本筋学会
- Place of Presentation
  国立精神・神経医療研究センター（東京都小平市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K14575
[Presentation] 神経筋接合部の出生後の維持におけるAgrinの新たな役割2015
- Author(s)
  手塚徹、井上茜、星太輔、Weatherbee SD、Burgess RW、植田亮、山梨裕司
- Organizer
  日本筋学会
- Place of Presentation
  国立研究開発法人国立精神・神経医療研究センター（東京都小平市）
- Year and Date
  2015-08-08
- Data Source
  KAKENHI-PROJECT-25460357
[Presentation] Involvement of NMDAR2A tyrosine phosphorylation in depression-related behavior.2009
- Author(s)
  中澤敬信、谷口幸子、谷村あさみ、城山優治、手塚徹、狩野方伸、真鍋俊也、山本雅
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21790266
[Presentation] The Novel NYAP phosphoprotein family couples activation of phosphoinositide 3-kinase (PI3K) p85 with the cytoskeletal WAVE signaling pathway in the brain.2009
- Author(s)
  横山一剛、手塚徹、小谷政晴、中澤敬信、星名直祐、井上毅、霜田靖、角田茂、須藤カツ子、渡邉和忠、岩倉洋一郎、山本雅
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21790266
[Presentation] Cblファミリー蛋白質による表皮形成制御2007
- Author(s)
  手塚徹, 他
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18022013

1. YAMANASHI Yuji (40202387)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. S Youssefian (00210576)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MINAMI YASUHIRO (70229772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MASHIMA Ryuichi (00401365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NUREKI Osamu (10272460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NATSUME Tohru (00357683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKEDA Shin'ICHI (90171644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. MOTOMURA Masakatsu (70244093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Koizumi Akio (50124574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. 土生敏行 (70346071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 小林果 (70542091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. 原田浩二 (80452340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. 植田亮 (10445025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Kim Minsoo (50466835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 水島恒裕 (90362269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 峰晴陽平 (50716602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 池谷真 (20442923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 舟木健史 (70555094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SHOHAB YOUSSEFIAN

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
20. 後藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 岡田尚已

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 岡田浩典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TEZUKA Tohru 手塚 徹

Research Projects

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Co-Researchers

Elucidation of the molecular mechanisms underlying type 2 inflammation in moyamoya disease.

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Functional analysis of heritable risk factors for moyamoya disease and strokePrincipal Investigator

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Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular society

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Signaling in NMJ formation and its synaptopathy

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Develpment of a new method to treat neuromuscular diseasesPrincipal Investigator

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Molecular mechanisms of the formation and maintenance of NMJsPrincipal Investigator

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細胞内リガンドによる受容体型チロシンキナーゼの活性化機構Principal Investigator

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Dysfunction of planar cell polarity signaling and its relationship with ciliopathies and cancer invasion and metastasis

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Molecular signaling in neuromuscular synaptogenesis and myasthenia

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Roles of Dok-7 and MuSK in neuromuscular synaptogenesisPrincipal Investigator

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Src及びCblファミリーによるチロシンリン酸化シグナルの正負の制御と脳高次機能Principal Investigator

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Src及びCblファミリーによるチロシンキナーゼシグナルの正負の制御と脳高次機能Principal Investigator

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Elucidation of roles of Cbl-family proteins in the nervous system.Principal Investigator

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TEZUKA Tohru 手塚徹

[Journal Article] DOK7　gene therapy enhances motor activity and life span in ALS model mice2017