yamazaki hirohito 山崎宏人

… Alternative Names

Researcher Number	50361994
Other IDs
External Links
Affiliation (Current)	2021: 金沢大学, 附属病院, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 金沢大学, 附属病院, 准教授 2015: 金沢大学, 大学病院, 准教授 2011 – 2012: 金沢大学, 大学病院, 講師 2010 – 2011: 金沢大学, 附属病院, 講師 2008: Kanazawa University, 附属病院, 助教 … More
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology
Keywords	Principal Investigator 再生不良性貧血 / PNH型血球 / 免疫抑制療法 / 抗DRS-1抗体 / 抗モエシン抗体 / 抗体モエシン抗体 / P同型血球 / トロンボポエチン / CD109 / TGF‐β … More Except Principal Investigator 再生不良性貧血 / 自己抗体 / DRS-1 / moesin / モエシン / 細胞傷害性T細胞 / hnRNPK / 免疫抑制療法 / 慢性関節リウマチ / 6pUPD / HLA / 自己抗原 / GPIアンカー膜蛋白 / PNH / TGF-β / CD109 / 骨髄不全 / PNH型血球 / GPI-アンカー膜蛋白 / 13q- / RB遺伝子 / 発作性夜間ヘモグロビン尿症 / 細胞障害性T細胞 / aplastic anemia / DRS / paroxysmal nocturnal hemoglobinuria / autoantibody / cytotoxic T cell Less

難治性再生不良性貧血におけるトロンボポエチン受容体作動薬の効果反応予測因子の同定Principal InvestigatorOngoing
- Principal Investigator
  
  山崎宏人
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kanazawa University
The role of CD109 and TGF-beta for the preferential commitment of PIGA mutant HSPCs in immune-mediated bone marrow failure.Principal Investigator
- Principal Investigator
  
  Yamazaki Hirohito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Development of the diagnostic system of bone marrow failure with a minor population of PNH-phenotype cellsPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Hirohito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Identification of auto-antigens which trigger the development of immune-mediated bone marrow failure
- Principal Investigator
  
  NAKAO Shinji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Identification of novel auto-antibodies and corresponding antigens in patients with aplastic anemia using CLIP replacement Ii chain library
- Principal Investigator
  
  NAKAO Shinji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Establishment of a method to predict the effects of immunosuppressive therapy for aplastic anemiaPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Hirohito
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Analysis of mechanisms responsible for clonal expansion of PNH-type hematopoietic stem cells mediated by autoreactive T cells in patients with bone marrow failure
- Principal Investigator
  
  NAKAO Shinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University

[Book] 骨髄異形成症候群(MDS)診療up-to-date「免疫抑制療法」(松田晃編)2011
- Author(s)
  山崎宏人
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22591032
[Book] 新しい診断と治療のABC 72再生不良性貧血「病態生理」(小澤敬也編)2011
- Author(s)
  山崎宏人
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-22591032
[Book] 血液疾患合併感染症(正岡徹 (編集))2008
- Author(s)
  山崎宏人
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Hematologic recovery induced by eltrombopag in Japanese patients with aplastic anemia refractory or intolerant to immunosuppressive therapy.2019
- Author(s)
  Yamazaki H, Ohta K, Iida H, Imada K, Obara N, Tokumine Y, Tomiyama Y, Usuki K, Imajo K, Miyamura K, Sasaki O, Fanghong Z, Hattori T, Tajima T, Matsuda A, Nakao S.
- Journal Title
  
  Int J Hematol
  
  Volume: 110 Pages: 187-196
- DOI
  10.1007/s12185-019-02683-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08318, KAKENHI-PROJECT-17K09898
[Journal Article] Prospective randomized trial comparing two doses of rabbit anti‐thymocyte globulin in patients with severe aplastic anaemia2019
- Author(s)
  Narita A, Zhu X, Muramatsu H, Chen X, Guo Y, Yang W, Zhang J, Liu F, Jang JH, Kook H, Kim H, Usuki K, Yamazaki H, Takahashi Y, Nakao S, Wook Lee J, Kojima S
- Journal Title
  
  British Journal of Haematology
  
  Volume: 187 Pages: 227-237
- DOI
  10.1111/bjh.16055
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08318, KAKENHI-PROJECT-19K08297
[Journal Article] Acquired aplastic anemia: recent advances in pathophysiology and treatment2018
- Author(s)
  山崎宏人
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 59 Issue: 6 Pages: 711-715
- DOI
  10.11406/rinketsu.59.711
- NAID
  130007393852
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08318
[Journal Article] Treatment strategy for acquired aplastic anemia2018
- Author(s)
  山崎宏人
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 59 Issue: 10 Pages: 1969-1978
- DOI
  10.11406/rinketsu.59.1969
- NAID
  130007496919
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08318
[Journal Article] Outcome of Second Transplantation Using Umbilical Cord Blood for Graft Failure after Allogeneic Hematopoietic Stem Cell Transplantation for Aplastic Anemia.2017
- Author(s)
  Onishi Y, Mori T, Kako S, Koh H, Uchida N, Kondo T, Kobayashi T, Yabe H, Miyamoto T, Kato K, Suzuki R, Nakao S, Yamazaki H
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: 23 Pages: 2137-2142
- DOI
  10.1016/j.bbmt.2017.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09496
[Journal Article] Acquired aplastic anemia2016
- Author(s)
  山崎宏人
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 57 Issue: 2 Pages: 91-97
- DOI
  10.11406/rinketsu.57.91
- NAID
  130005132705
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09496
[Journal Article] Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia.2016
- Author(s)
  Maruyama H, Katagiri T, Kashiwase K, Shiina T, Sato-Otsubo A, Zaimoku Y, Maruyama K, Hosokawa K, Ishiyama K, Yamazaki H, Inoko H, Ogawa S, Nakao S
- Journal Title
  
  Exp Hematol
  
  Volume: 44 Pages: 931-939
- DOI
  10.1016/j.exphem.2016.05.013
- NAID
  120005895697
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26860363, KAKENHI-PROJECT-15K09496
[Journal Article] Hypomegakaryocytic thrombocytopenia (HMT): an immune-mediated bone marrow failure characterized by an increased number of PNH-phenotype cells and high plasma thrombopoietin levels.2016
- Author(s)
  Saito C, Ishiyama K, Yamazaki H, Zaimoku Y, Nakao S.
- Journal Title
  
  Br J Haematol
  
  Volume: 175 Pages: 246-251
- DOI
  10.1111/bjh.14210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09496
[Journal Article] Cyclosporine restores hematopoietic function by compensating for decreased Tregs in patients with pure red cell aplasia and acquired aplastic anemia.2016
- Author(s)
  Dao AT, Yamazaki H, Takamatsu H, Sugimori C, Katagiri T, Maruyama H, Zaimoku Y, Maruyama K, Ly TQ, Espinoza L, Nakao S
- Journal Title
  
  Ann Hematol
  
  Volume: 95 Pages: 771-781
- DOI
  10.1007/s00277-016-2629-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14F04419, KAKENHI-PROJECT-26860363, KAKENHI-PROJECT-15K09496
[Journal Article] Increased glycosylphosphatidylinositol-anchored protein-deficient granulocytes define a benign subset of bone marrow failures in patients with trisomy 82015
- Author(s)
  Hosokawa K, Sugimori N, Katagiri T, Sasaki Y, Saito C, Seiki Y, Mochizuki K, Yamazaki H, Takami A, Nakao S.
- Journal Title
  
  Eur J Haematol
  
  Volume: 18 Pages: 230-238
- DOI
  10.1111/ejh.12484
- NAID
  120005661927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14F04419, KAKENHI-PROJECT-24390243, KAKENHI-PROJECT-24591418, KAKENHI-PROJECT-25670448, KAKENHI-PROJECT-26860363, KAKENHI-PROJECT-15K09496, KAKENHI-PROJECT-15K09513
[Journal Article] Hematopoietic stem cell transplantation for acquired aplastic anemia2015
- Author(s)
  山崎宏人
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 56 Issue: 10 Pages: 2153-2159
- DOI
  10.11406/rinketsu.56.2153
- NAID
  130005103281
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09496
[Journal Article] Increased plasma thrombopoietin levels in patients with myelodysplastic syndrome: a reliable marker for a benign subset of bone marrow failure2013
- Author(s)
  Seiki Y, Sasaki Y, Hosokawa K, Saito C, Sugimori N, Yamazaki H, Takami A, Nakao S
- Journal Title
  
  Haematologica
  
  Volume: 98(in press)
- DOI
  10.3324/haematol.2012.066217
- NAID
  120005312328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591032, KAKENHI-PROJECT-23659486
[Journal Article] An Epstein-Barr virus-associated leukemic lymphoma in a patient treated with rabbit antithymocyte globulin and cyclosporine for hepatitis-associated aplastic anemia2012
- Author(s)
  Ohata K, Iwaki N, Kotani T, Kondo Y, Yamazaki H, Nakao S
- Journal Title
  
  Acta Haematol
  
  Volume: 127 Pages: 96-99
- NAID
  120003752533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] 再生不良性貧血の病態と治療:病態診断を活用した治療戦略2011
- Author(s)
  山崎宏人
- Journal Title
  
  臨床血液
  
  Volume: 52 Pages: 1507-1514
- NAID
  10029768666
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] 再生不良性貧血2011
- Author(s)
  山崎宏人
- Journal Title
  
  Mebio
  
  Volume: 28 Pages: 54-63
- NAID
  130005132705
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] AAの病態と治療:病態診断を活用した治療戦略2011
- Author(s)
  山崎宏人
- Journal Title
  
  臨床血液
  
  Volume: 52 Pages: 1507-1514
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21971227
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] An Epstein-Barr virus-associated leukemic lymphoma in a patient treated with rabbit antithymocyte globulin and cyclosporine for hepatitis-associated aplastic anemia2011
- Author(s)
  Ohata, K., Iwaki, N., Kotani, T., Kondo, Y., Yamazaki, H., Nakao, S.
- Journal Title
  
  Acta Haematol
  
  Volume: 127 Pages: 96-99
- NAID
  120003752533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390291
[Journal Article] 再生不良性貧血の診断と治療:セカンドオピニオン外来で聞かれること2010
- Author(s)
  山崎宏人
- Journal Title
  
  臨床血液
  
  Volume: 51 Pages: 1441-1449
- NAID
  10026727987
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] AAの診断と治療:セカンドオピニオン外来で聞かれること2010
- Author(s)
  山崎宏人
- Journal Title
  
  臨床血液
  
  Volume: 51 Pages: 1441-1449
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] Autoantibodies specific to hnRNP K: a new diagnostic marker for immune pathophysiology in aplastic anemia2010
- Author(s)
  Qi Z, Takamatsu H, Espinoza JL, Lu X, Sugimori N, Yamazaki H, Okawa, K. Nakao, S
- Journal Title
  
  Ann Hematol
  
  Volume: 89 Pages: 1255-1263
- DOI
  10.1007/s00277-010-1020-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] 成人再生不良性貧血に対するサイモグロブリン療法2010
- Author(s)
  山崎宏人, 中尾填二
- Journal Title
  
  血液フロンティア
  
  Volume: 20 Pages: 693-699
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] Autoantibodies specific to hnRNP K : a new diagnostic marker for immune pathophysiology in aplastic anemia2010
- Author(s)
  Qi, Z., Takamatsu, H., Espinoza, J, L., Lu, X., Sugimori, N., Yamazaki, H., Okawa, K., Nakao, S.
- Journal Title
  
  Ann Hematol
  
  Volume: 89 Pages: 1255-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390291
[Journal Article] Autoantibodies specific to hnRNP K : a new diagnostic marker for immune pathophysiology in aplastic anemia.2010
- Author(s)
  Qi Z, Takamatsu H, Espinoza JL, Lu X, Sugimori N, YamazakiH, Okawa K, Nakao S.
- Journal Title
  
  Annals of Hematology
  
  Volume: Vol89 Pages: 1255-1263
- Data Source
  KAKENHI-PROJECT-22591032
[Journal Article] Aberrant increase in the immature platelet fraction in patients with myelodysplastic syndrome : a marker of karyotypic abnormalities associated with poor prognosis Eur J Haematol2009
- Author(s)
  Sugimori N, Kondo Y, Shibayama M, Omote M, Takami A, Sugimori C, Ishiyama K, Yamazaki H, Nakao S
- Journal Title
  
  82
  
  Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390260
[Journal Article] Origin and fate of blood cells deficient in glycosylphosphatidylinositol-anchored protein among patients with bone marrow failure2009
- Author(s)
  Sugimori, C., Mochizuki, K., Qi, Z., Sugimori, N., Ishiyama, K., Kondo, Y., Yamazaki, H., Takami, A., Okumura, H., Nakao, S.
- Journal Title
  
  Br J Haematol
  
  Volume: 147 Pages: 102-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390291
[Journal Article] Cord blood transplantation using minimum conditioning regimens for patients with hematologic malignancies complicated by severe infections2009
- Author(s)
  Yamashita T, Yamazaki H, Nakao S., (8人・(4)番目)
- Journal Title
  
  Int J Hematol. 89
  
  Pages: 238-42
- NAID
  10025160388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Origin and fate of blood cells deficient in glycosylphosphatidylino sitol-anchored protein among patients with bone marrow failure.2009
- Author(s)
  Sugimori C, Mochizuki K, Qi Z, Sugimori N, Ishiyama K, Kondo Y, Yamazaki H, Takami A, Okumura H, Nakao S
- Journal Title
  
  Br J Haematol 147
  
  Pages: 102-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390291
[Journal Article] Aberrant increase in the immature platelet fraction in patients with myelodysplastic syndrome : a marker of karyotypic abnormalities associated with poor prognosis2009
- Author(s)
  Sugimori N, Yamazaki H, Nakao S., (9人・(8)番目)
- Journal Title
  
  Eur J Haematol 82
  
  Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Danazol therapy for aplastic anemia refractory to immunosuppressive therapy2008
- Author(s)
  Chuhjo T, Yamazaki H, Nakao S., (4人・(2)番目)
- Journal Title
  
  Am J Hematol 83
  
  Pages: 387-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] A marked increase in myeloblasts in the peripheral blood of a patient with Burkitt lymphoma following G-CSF administration2008
- Author(s)
  Takamatsu H, Yamazaki H, Nakao S., (6人・(3)番目)
- Journal Title
  
  Acta Haematologica 120
  
  Pages: 174-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] CD16+ CD56- NK cells in the peripheral blood of cord blood transplant recipients : a unique subset of NK cells possibly associated with graft-versusleukemia effect2008
- Author(s)
  Lu X, Yamazaki H, Nakao S., (8人・(5)番目)
- Journal Title
  
  Eur J Haematol 81
  
  Pages: 18-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Expansion of donor-derived hematopoietic stem cells with PIGA mutation associated with late graft failure after allogeneic stem cell transplantation2008
- Author(s)
  Mochizuki K, Yamazaki H, Nakao S., (10人・(8)番目
- Journal Title
  
  Blood 112
  
  Pages: 2160-21
- NAID
  120000807462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Expansion of donorderived hematopoietic stemcells with PIGA mutation associated with late graft failure after allogeneic stem cell transplantation2008
- Author(s)
  Mochizuki K, Sugimori C, Qi Z, Lu X, Takami A, Ishiyama K, Kondo Y, Yamazaki H, Okumura H, Nakao S
- Journal Title
  
  Blood 112
  
  Pages: 2160-2162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390260
[Journal Article] Cyclosporine therapy for acquired aplastic anemia : Predictive factors for theresponse and long-term prognosis.2007
- Author(s)
  Hirohito Yamazaki
- Journal Title
  
  International Journal of Hematology (印刷中)
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Roles of DRB1 *1501 and DRB1 *1502 in the pathogenesis of aplastic anemia2007
- Author(s)
  Sugimori C, Yamazaki H, Feng X, Mochizuki K, Kondo Y, Takami A, Chuhjo T, Kimura A, Teramura M, Mizoguchi H, Omine M, Nakao S
- Journal Title
  
  Exp Hematol 35
  
  Pages: 13-20
- NAID
  120000809590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390260
[Journal Article] Cyclosporine therapy for acquired aplastic anemia:Predictive factors for the response and long-term prognosis2007
- Author(s)
  Hirohito Yamazaki
- Journal Title
  
  International Journal of Hematology 85
  
  Pages: 186-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Cyclosporine therapy for acquired aplastic anemia : predictive factors for the response and long-term prognosis2007
- Author(s)
  Yamazaki H, Sugimori C, Chuhjo T, Nakao S.
- Journal Title
  
  Int J Hematol 85
  
  Pages: 186-190
- NAID
  10019488749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390260
[Journal Article] Roles of DRB1 *1501 and DRB1 *1502 in the pathogenesis of aplastic anemia2007
- Author(s)
  Sugimori C, Yamazaki H, Nakao S., (12人・(2)番目)
- Journal Title
  
  Exp Hematol 35
  
  Pages: 13-20
- NAID
  120000809590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Cyclosporine therapy for acquired aplastic anemia: predictive factors for the response and long-term prognosis.2007
- Author(s)
  Yamazaki, H., et. al.
- Journal Title
  
  Int J Hematol 85
  
  Pages: 186-190
- NAID
  10019488749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390260
[Journal Article] Cyclosporine therapy for acquired aplastic anemia : predictive factors for the response and long-term prognosis2007
- Author(s)
  Yamazaki H, Nakao S., (4人・(1)番目)
- Journal Title
  
  Int J Hematol 85
  
  Pages: 186-190
- NAID
  10019488749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Minor population of CD55-CD59-blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia.2006
- Author(s)
  Sugimori C, Chuhjo T, Feng X, Yamazaki H, Takami A, Teramura M, Mizoguchi H, Omine M, Nakao S
- Journal Title
  
  3lood. 107(4)
  
  Pages: 1308-1314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390275
[Journal Article] Clinical significance of a small population of paroxysmal nocturnal hemoglobinuria-type cells in the management of bone marrow failure2006
- Author(s)
  Nakao S, Yamazaki H., (3人・(3)番目)
- Journal Title
  
  Int J Hematol 84
- NAID
  10019284630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Reduced-intensity unrelated cord blood transplantation for treatment of metastatic renal cell carcinoma : first evidence of cord-bloodversus-solid-tumor effect2006
- Author(s)
  Takami A, Yamazaki H, Nakao S., (10人・(3)番目)
- Journal Title
  
  Bone Marrow Transplant 38
  
  Pages: 729-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Clinical significance of a small population of paroxysmal nocturnal hemoglobinuria-type cells in the management of bone marrow failure.2006
- Author(s)
  Nakao S, Sugimori C, Yamazaki H
- Journal Title
  
  nt JHematol. 84(2)
  
  Pages: 118-122
- NAID
  10019284630
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390275
[Journal Article] Roles of DRB1 * 1501 and DRB1*1502 in the pathogenesis of aplastic anemia.2006
- Author(s)
  Sugimori C, Yamazaki H, Feng X, Mochizuki K, Kondo Y, Takami A, Chuhjo T, Kimura A, Teramura M, Mizoguchi H, Omine M, Nakao S
- Journal Title
  
  ExpHematol. 35(1)
  
  Pages: 13-20
- NAID
  120000809590
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390275
[Journal Article] Reduced-intensity unrelated cord blood transplantation for treatment of metastatic renal cell carcinoma : first evidence of cord-blood-versus-solid-tumor effect.2006
- Author(s)
  Takami A, Takamatsu H, Yamazaki H, Ishiyama K, Okumura H, Ohata K, Konaka H, Asakura H, Namiki M, Nakao S
- Journal Title
  
  3one Marrow Transplant 38(11)
  
  Pages: 729-732
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390275
[Journal Article] Minor population of CD55-CD59- blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia2006
- Author(s)
  Sugimori C, Yamazaki H, Nakao S., (9人・(4)番目)
- Journal Title
  
  Blood 107
  
  Pages: 1308-1314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591050
[Journal Article] Isolated hyperkalemia associated with cyclosporine administration in allogeneic stem cell transplantation for renal cell carcinoma.2005
- Author(s)
  Takami A, Asakura H, Takamatsu H, Yamazaki H, Arahata M, Hayashi T, Shibayama M, Onto M, Yoshida T, Namiki M, Nakao S
- Journal Title
  
  IntJHematol. 81
  
  Pages: 159-161
- NAID
  10014372551
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390275
[Journal Article] High incidence of cytomegalovirus reactivation in adult recipients of an unrelated cord blood transplant.2005
- Author(s)
  Takami A, Mochizuki K, Asakura H, Yamazaki H, Okumura H, Nakao S
- Journal Title
  
  Haematologica. 90(9)
  
  Pages: 1290-1292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390275
[Patent] PNH型白血球の検出方法2010
- Inventor(s)
  中尾眞二、杉盛千春、片桐孝和、清木ゆう、杉森尚美、山崎宏人、細川晃平
- Industrial Property Rights Holder
  中尾眞二、杉盛千春、片桐孝和、清木ゆう、杉森尚美、山崎宏人、細川晃平
- Filing Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21390291
[Presentation] The erythropoietic reserve correlates with the response to eltrombopag in refractory aplastic anemia2019
- Author(s)
  Ken Ishiyama, Hirohito Yamazaki, Kohei Hosokawa, Tatsuya Imi, Hiroki Mizumaki, Mikoto Tanabe, Noriaki Tsuji
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] Persistent immune selection of HLA-lacking HSPCs in convalescent patients with aplastic anemia2019
- Author(s)
  Noriaki Tsuji, Kohei Hosokawa, Mikoto Tanabe, Takeshi Yoroidaka, Hiroki Mizumaki, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Shinji Nakao
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] A GPI-anchored protein CD109 protects TF-1 cells from undergoing differentiation induced by TGF-β2019
- Author(s)
  Mikoto Tanabe, Noriharu Nakagawa, Kohei Hosokawa, Thinguyen Maianh, Espinoza Luis, Kana Maruyama, Takamasa Katagiri, Hirohito Yamazaki, Shinji Nakao
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] The high NK cell count at diagnosis predicts a good response to IST in aplastic anemia2019
- Author(s)
  Atsushi Narita, Hideki Muramatsu, Yinyan Xu, Motoharu Hamada, Daisuke Ichikawa, Eri Nishikawa, Nozomu Kawashima, Yusuke Okuno, Nobuhiro Nishio, Hirohito Yamazaki, Shinji Nakao, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β2019
- Author(s)
  Tanabe Mikoto, Nguyen Hoang Maianh, Kohei Hosokawa, Noriharu Nakagawa, Luis Espinoza, Hirohito Yamazaki, Shinji Nakao
- Organizer
  61st ASH Annual meeting（第61回アメリカ血液学会）
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] Limited class I HLAs are involved in the auto-antigen presentation in acquired aplastic anemia2018
- Author(s)
  Mikoto Tanabe, Hiroki Mizumaki, Tatsuya Imi, Takeshi Yoroidaka, Noriharu Nakagawa, Ken Ishiyama, Hirohito Yamazaki, Yoshiraka Zaimoku, Takamasa Katagiri, Kazuyoshi Hosomichi, Atsushi Tajima, Shinji Nakao
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] Familial acquired aplastic anemia diagnosed by aberrant leukocytes that lacked common HLA alleles2018
- Author(s)
  Tatsuya Imi, Ryosuke Ogawa, Kazuyoshi Hosomichi, Hiroki Mizumaki, Noriharu Nakagawa, Takeshi Yoroidaka, Mikoto Tanabe, Noriaki Tsuji, Kohei Hosokawa, Hiroyuki Takamatsu, Ken Ishiyama, Yukio Kondo, Hirohito Yamazaki, Atsushi Tajima, Shinji Nakao
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] 再生不良性貧血の治療戦略2018
- Author(s)
  山崎宏人
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] Reticulocyte counts over 30,000/μL predict a good response to eltrombopag in refractory AA2018
- Author(s)
  Keijiro Sato, Ken Ishiyama, Masahisa Arahata, Kohei Hosokawa, Yukio Kondo, Hirohito Yamazaki, Shinji Nakao
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] Response to IST in PNH(+) BMF patients with a history of chemo- or radiotherapy2018
- Author(s)
  Noriharu Nakagawa, Mikoto Tanabe, Ishikazu Mizuno, Satoshi Morishige, Shuji Matsuzawa, Takahiko Ito, Masahiko Sumi, Nobuyuki Takayama, Ken Ishiyama, Hirohito Yamazaki, Shinji Nakao
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] The depletion of TGF-β co-receptor CD109 induces erythroid differentiation of TF-1 cells: a model of preferential commitment of PIGA-mutated hematopoietic stem cells in immune-mediated bone marrow failure.2018
- Author(s)
  Tanabe Mikoto, Noriharu Nakagawa, Kohei Hosokawa, Luis Espinoza, Kana Maruyama, Takamasa Katagiri, Hirohito Yamazaki, Shinji Nakao
- Organizer
  The 60th ASH annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08318
[Presentation] 再生不良性貧血の病態診断と治療選択2017
- Author(s)
  山崎宏人
- Organizer
  第65回日本輸血・細胞治療学会総会
- Data Source
  KAKENHI-PROJECT-15K09496
[Presentation] Relatively low sensitivity of CD109(-) hematopoietic stem/progenitor cells (HSPCs) to TGF-β: A possible mechanism responsible for the preferential commitment of PIGA mutant HSPCs in immune-mediated bone marrow failure.2016
- Author(s)
  Nakagawa N, Hosokawa K, Espinosa L, Maruyama K, Katagiri K, Yamazaki H, Nakao S
- Organizer
  第58回米国血液学会議
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09496
[Presentation] Prevalence pf PNH-type cells in cases of chronic thrombocytopenia that can be diagnosed with ITP.2016
- Author(s)
  Yamazaki H, Sugimori N, Maruyama K, Zaimoku Y, Maruyama H, Nakagawa N, Saito C, Imi T, Sugimori C, Ishiyama K, Nakao S
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09496
[Presentation] 再生不良性貧血に対する造血幹細胞移植2015
- Author(s)
  山崎宏人
- Organizer
  第77回日本血液学会学術集会（教育講演）
- Place of Presentation
  ホテル金沢（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09496
[Presentation] Evidence That T Cells Specific for Non-Hematopoietic Cells Trigger the Development of Acquired Aplastic Anemia2015
- Author(s)
  Tatsuya Imi, Hiroyuki Maruyama, Takamasa Katagiri, Yoshitaka Zaimoku, Kana Maruyama, Noriharu Nakagawa, Kohei Hosokawa, Ken Ishiyama, Hirohito Yamazaki, Koichi Kashiwase, Shinji Nakao
- Organizer
  57th ASH Annual Meeting
- Place of Presentation
  オーランド（アメリカ）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15K09496
[Presentation] Evidence for a Common Immune Pathophysiology in Acquired Aplastic Anemia and Ulcerative Colitis2015
- Author(s)
  Noriharu Nakagawa, Hiroyuki Maruyama, Yoshitaka Zaimoku, Kana Maruyama, Chizuru Saito, Takamasa Katagiri, Kohei Hosokawa, Ken Ishiyama, Hirohito Yamazaki, Shinji Nakao
- Organizer
  57th ASH Annual Meeting
- Place of Presentation
  オーランド（アメリカ）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15K09496
[Presentation] 再生不良性貧血の病態と治療:病態診断を活用した治療戦略2011
- Author(s)
  山崎宏人
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)(教育講演)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] Thymoglobulin therapy for aplastic anemia : impact of PNH-type cells on the treatment outcome2011
- Author(s)
  Yamazaki H
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] AAの病態と治療:病態診断を活用した治療戦略(教育講演)2011
- Author(s)
  山崎宏人
- Organizer
  日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] Thymoglobuline is as effective as Lymphoglobuline in Japanese patients with aplastic anemia possessing increased glycosylphosphatidylinositol-anchored protein (GPI-AP) deficient cells2011
- Author(s)
  Yamazaki H
- Organizer
  2011 ASH Annual Meeting
- Place of Presentation
  San Diego Convention Center(USA)
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] Thymoglobulin therapy for aplastic anemia: impact of PNH-type cells on the treatment outcome2011
- Author(s)
  Yamazaki H
- Organizer
  日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] Thymoglobuline is as effective as Lymphoglobuline in Japanese patients with aplastic anemia possessing increased glycosylphosphatidylinositol-anchored protein (GPI-AP) deficient cells2011
- Author(s)
  Yamazaki H
- Organizer
  2011 ASH Annual Meeting
- Place of Presentation
  San Diego Convention Center(アメリカ)
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] AAの診断と治療:セカンドオピニオン外来で聞かれること(教育講演)2010
- Author(s)
  山崎宏人
- Organizer
  日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] 再生不良性貧血の診断と治療:セカンドオピニオン外来で聞かれること2010
- Author(s)
  山崎宏人
- Organizer
  日本血液学会
- Place of Presentation
  パシフィコ横浜(神奈川県)(教育講演)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22591032
[Presentation] C3を指標としたシクロスポリンによる急性GVHD予防法の検討 : 多施設共同臨床試験の成績2009
- Author(s)
  山崎宏人, 日野雅之, 古川達雄, 森下剛久, 宇都宮與, 今村雅寛, 鬼塚真仁, 新津洋司郎, 笠井正晴, 田嶋克史, 梅原久範, 島崎千尋, 谷口修一, 今村豊, 中尾眞二
- Organizer
  第31回日本造血細胞移植学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-02-05
- Data Source
  KAKENHI-PROJECT-18591050
[Presentation] 骨髄不全患者における染色体異常 : PNH型血球の増加からみた各種染色体異常の臨床的意義2008
- Author(s)
  杉森尚美, 山崎宏人, 杉盛千春, 石山謙, 片桐孝和, 中尾眞二
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591050
[Presentation] 血小板減少患者におけるPNH型血球検出の臨床的意義2008
- Author(s)
  石山謙, 杉森尚美, 片桐孝和, 山崎宏人, 杉盛千春, 中尾眞二
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591050
[Presentation] 蛋白同化ステロイド二次不応再生不良性貧血におけるシクロスポリン追加投与の有用性2008
- Author(s)
  山崎宏人, 中尾眞二
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591050
[Presentation] 再生不良性貧血患者にみられる微少PNH型顆粒球は単一のPIG-A変異クローンに由来する2007
- Author(s)
  望月果奈子, 杉盛千春, 山崎宏人, 高見昭良, 中尾眞二
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591050
[Presentation] 移植後再発・生着不全に対する臍帯血ミニ移植の有用性2007
- Author(s)
  山崎宏人, 高見昭良, 近藤恭夫, 奥村廣和, 中尾眞二
- Organizer
  第29回日本造血細胞移植学会総会
- Place of Presentation
  福岡
- Year and Date
  2007-02-16
- Data Source
  KAKENHI-PROJECT-18591050

1. NAKAO Shinji (70217660)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. TAKAMATSU Hiroyuki (70401932)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. KONDO Yukio (10322116)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. TAKAMI Akiyoshi (80324078)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. SENJYU Satoru (50274709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ISHIYAMA Ken (60377380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. KOMATSUZAKI Toshihiko (80293372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YACHIE Akihiro (40210281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Sato Aiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中尾真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 45 results
11. 片桐孝和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 椎名隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 小原直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 成田敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yamazaki hirohito 山崎 宏人

Yamazaki Hirohito 山崎 宏人

YAMAZAKI Hirohito 山崎 宏人

Research Projects

Research Products

Co-Researchers

難治性再生不良性貧血におけるトロンボポエチン受容体作動薬の効果反応予測因子の同定Principal InvestigatorOngoing

Principal Investigator

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Research Institution

The role of CD109 and TGF-beta for the preferential commitment of PIGA mutant HSPCs in immune-mediated bone marrow failure.Principal Investigator

Principal Investigator

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Research Institution

Development of the diagnostic system of bone marrow failure with a minor population of PNH-phenotype cellsPrincipal Investigator

Principal Investigator

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Research Institution

Identification of auto-antigens which trigger the development of immune-mediated bone marrow failure

Principal Investigator

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Research Field

Research Institution

Identification of novel auto-antibodies and corresponding antigens in patients with aplastic anemia using CLIP replacement Ii chain library

Principal Investigator

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Research Institution

Establishment of a method to predict the effects of immunosuppressive therapy for aplastic anemiaPrincipal Investigator

Principal Investigator

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Research Institution

Analysis of mechanisms responsible for clonal expansion of PNH-type hematopoietic stem cells mediated by autoreactive T cells in patients with bone marrow failure

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Research Institution

[Book] 骨髄異形成症候群(MDS)診療up-to-date「免疫抑制療法」(松田晃編)2011

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Data Source

[Book] 新しい診断と治療のABC 72再生不良性貧血「病態生理」(小澤敬也編)2011

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[Book] 血液疾患合併感染症(正岡徹 (編集))2008

Author(s)

Publisher

Data Source

[Journal Article] Hematologic recovery induced by eltrombopag in Japanese patients with aplastic anemia refractory or intolerant to immunosuppressive therapy.2019

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Journal Title

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[Journal Article] Prospective randomized trial comparing two doses of rabbit anti‐thymocyte globulin in patients with severe aplastic anaemia2019

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[Journal Article] Acquired aplastic anemia: recent advances in pathophysiology and treatment2018

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[Journal Article] Treatment strategy for acquired aplastic anemia2018

Author(s)

yamazaki hirohito 山崎宏人

Yamazaki Hirohito 山崎宏人

YAMAZAKI Hirohito 山崎宏人