KAWAI Kumi 川井久美

Researcher Number	50362231
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2021: 名古屋大学, 医学系研究科(保健), 准教授 2016: 名古屋大学, 医学系研究科(保健), 准教授 2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 准教授 2009 – 2011: Aichi Medical University, 医学部, 講師 2005 – 2006: 名古屋大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Experimental pathology / Laboratory medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Experimental pathology / Human pathology
Keywords	Principal Investigator RET / モデルマウス / キナーゼ阻害剤 / プロテオーム解析 / 網羅的タンパク質リン酸化解析 / モデル動物 / チロシンキナーゼ阻害剤 / 分子標的薬 / プロテオミクス解析 / 甲状腺髄様癌 … More / 甲状腺髄様がん / 癌 / チロシンキナーゼインヒビター / 遺伝子操作動物 / 甲状腺がん / MEN2A型 / MKPfamily / トランスジェニックマウス / 多発性内分泌腫瘍症2A型 … More Except Principal Investigator 創薬 / 肺癌 / REV7 / ドライバー遺伝子 / ドライバー癌遺伝子 / 創薬研究 / 細胞老化 / 変異KRAS / 上皮間葉細胞転換 / knockout mouse / translesion DNA synthesis / DNA repair / damage tolerance / 損傷乗り換え型DNA複製 / DNA損傷 / ノックアウトマウス / 損傷乗り越え型DNA複製 / DNA修復 / 損傷トレランス / 腫瘍幹細胞 / 神経芽腫幹細胞 / 交感神経神経堤幹細胞 / 神経芽腫 / 副腎髄質 / 細胞表面マーカー / 分化階層 / 神経芽細胞種 / 幹細胞 / 表面マーカー / 神経芽細胞腫 Less

Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transition
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Nagoya University
Development of novel therapeutics that utilize driver oncogene-induced senescence
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Phosphoproteomic analysis of RET kinase signal in MTC model micePrincipal Investigator
- Principal Investigator
  
  Kawai Kumi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Identification and analysis of the stem cells and its differentiation in sympathetic neural crest cells and neuroblastoma cells
- Principal Investigator
  
  KUROKAWA Kei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  The Japanese Red Cross Toyota College of Nursing
New Tyrosine kinase inhibitor for thyroid medullary carcinoma treatmentPrincipal Investigator
- Principal Investigator
  
  KAWAI Kumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Aichi Medical University
多発性内分泌腫瘍症モデルマウスを用いた発がんの分子機序の解析Principal Investigator
- Principal Investigator
  
  川井久美
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University
Generation and Characterization of Knockout Mice Targeting REV7 gene, which is involved in DNA damage tolerance
- Principal Investigator
  
  MURAKUMO Yoshiki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University

All 2020 2016 2015 2014 2012 2011 2009 Other

All Journal Article Presentation Book

[Book] 病理と臨床臨時増刊号 vol.34 癌の分子病理学　病理診断から治療標的探索まで2016
- Author(s)
  川井久美、榎本篤
- Total Pages
  8
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25460682
[Book] 標準理学療法学・作業療法学　病理学4版2016
- Author(s)
  川井久美, 横井豊治, 村雲芳樹編集
- Total Pages
  32
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25460682
[Book] スタンダード病理学第４版2015
- Author(s)
  川井久美
- Total Pages
  16
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25460682
[Journal Article] UHRF1, a Regulator of Methylation, as a Diagnostic and Prognostic Marker for Lung Cancer2020
- Author(s)
  Goto Daiki、Komeda Kazuki、Uwatoko Natsuki、Nakashima Moeka、Koike Mayu、Kawai Kaho、Kodama Yuta、Miyazawa Ayako、Tanaka Ichidai、Hase Tetsunari、Morise Masahiro、Hasegawa Yoshinori、Kawabe Tsutomu、Sato Mitsuo
- Journal Title
  
  Cancer Investigation
  
  Volume: 38 Issue: 4 Pages: 240-249
- DOI
  10.1080/07357907.2020.1747483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-18H02819
[Journal Article] RET遺伝子研究の歩みと甲状腺癌2016
- Author(s)
  川井久美, 高橋雅英
- Journal Title
  
  Thyroid Cancer explore
  
  Volume: 2 Pages: 25-31
- Data Source
  KAKENHI-PROJECT-25460682
[Journal Article] RET遺伝子研究の歩みと甲状腺癌2016
- Author(s)
  川井久美、高橋雅英
- Journal Title
  
  Thyroid Cancer Explore
  
  Volume: 2
- Data Source
  KAKENHI-PROJECT-25460682
[Journal Article] 多発性内分泌腫瘍症2016
- Author(s)
  川井久美, 榎本篤
- Journal Title
  
  病理と臨床
  
  Volume: 34 Pages: 375-377
- Data Source
  KAKENHI-PROJECT-25460682
[Journal Article] Ovarian mucinous tumors arising from mature cystic teratomas--a molecular genetic approach for understanding the cellular origin.2014
- Author(s)
  Fujii K, Yamashita Y, Yamamoto T, Takahashi K, Hashimoto K, Miyata T, Kawai K, Kikkawa F, Toyokuni S, Nagasaka T
- Journal Title
  
  Hum Pathol
  
  Volume: 45 Issue: 4 Pages: 717-724
- DOI
  10.1016/j.humpath.2013.10.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590394, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-25460682, KAKENHI-PROJECT-25670342, KAKENHI-PROJECT-26460423, KAKENHI-PROJECT-24405017
[Journal Article] Fat embolism syndrome: an autopsy-proven case involving a patient on dialysis and systemic scleroderma2014
- Author(s)
  Nahoko Nishimura, Shogo Banno, Yukihiro Kimura, Sayaka Maeda, Mizuki Kobayashi, Kumi Kawai, Norihiro Suga, Keisuke Suzuki, Naoto Miura, Toyoharu Yokoi and Hirokazu Imai
- Journal Title
  
  Clinical Medicine Insights Case Reports
  
  Volume: 7 Pages: 7-12
- DOI
  10.4137/ccrep.s12636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460682
[Journal Article] Revisiting a medical case of "stinging" in the human oral cavity caused by ingestion of raw squid(Cephalopoda : Teuthida): new data on the functioning of squid's spermatophores2012
- Author(s)
  Jose Eduardo A. R. Marian, Yukihiro Shiraki, Kumi Kawai, Sawako Kojima, Yasuhiko Suzuki and Kenzo Ono
- Journal Title
  
  Zoomorphology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790395
[Journal Article] Ret finger protein inhibits muscle differentiation by modulating serum response factor and enhancer of polycomb12011
- Author(s)
  Hae Jin Kee, Ju-Ryoung Kim, Hosouk Joung, Nakwon Choe, Song Eun Lee, Gwang Hyeon Eom, Jeong Chul Kim, Stefan H Geyer, Mayumi Jijiwa, Takuya Kato, Kumi Kawai, Wolfgang J Weninger, Sang-Beom Seo, Kwang-Il Nam, Myung Ho Jeong, Masahide Takahashi and Hyun Kook
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 121-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790395
[Journal Article] Stinging in the oral cavity caused by ingestion of the sperm bags of a squid : A case report2011
- Author(s)
  Yukihiro Shiraki, Kumi Kawai, Sawako Kojima, Yasuhiko Suzuki and Kenzo Ono
- Journal Title
  
  Pathol Int
  
  Volume: 61 Pages: 749-751
- NAID
  10031185151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790395
[Journal Article] 多発性内分泌腫瘍症(MEN)2011
- Author(s)
  川井久美、今井常夫、高橋雅英
- Journal Title
  
  病理と臨床
  
  Volume: 29 Pages: 711-717
- Data Source
  KAKENHI-PROJECT-21790395
[Journal Article] Loss of Sprouty2 partially rescues renal hypoplasia and stomach hypoganglionosis but not intestinal aganglionosis in Ret Y1062F mutant mice2011
- Author(s)
  Rieko Miyamoto, Mayumi, Jijiwa, Masato Asai, Kumi Kawai, Maki Ishida-Takagishi, Shinji Mii, Naoya Asai, Atsushi Enomoto, Yoshiki Murakumo, Akihiko Yoshimura and Masahide Takahashi
- Journal Title
  
  Developmental Biololgy
  
  Volume: 349 Pages: 160-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790395
[Journal Article] Pleasure and Tullia Lindsten Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK2009
- Author(s)
  Kumi Kawai, Takayuki Itoh, Aki Itoh, Makoto Horiuchi, Kouji Wakayama, Peter Bannerman, James Y Garbern, David
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 30 Pages: 2030-2031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790395
[Journal Article] Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK2009
- Author(s)
  Kawai K.
- Journal Title
  
  Eur.J.Neurosci. 30
  
  Pages: 2030-2041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790395
[Presentation] 切片厚が乳癌HER2免疫染色に及ぼす影響2016
- Author(s)
  高須大輔, 新免望, 竹内優里, 宮地絵理, 宮川純奈, 加藤衣央, 佐藤浩司, 鈴木利明, 橋本克訓,川井久美
- Organizer
  第11回日本臨床検査学教育学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-25460682
[Presentation] MEN2A 型変異RETを有する甲状腺髄様がん細胞におけるチロシンキナーゼ阻害薬の効果の検討2015
- Author(s)
  舩戸連嗣、橋本克訓、川井久美
- Organizer
  第１０４回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-25460682
[Presentation] 甲状腺髄様癌とRET遺伝子の分子生物学2011
- Author(s)
  川井久美
- Organizer
  第44回甲状腺外科学会学術集会
- Place of Presentation
  米子BIGSHIP(鳥取)
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-21790395
[Presentation] オリゴデンドロサイトの発生制御におけるBAX/BAKの役割の解析2009
- Author(s)
  川井久美
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-21790395
[Presentation] in vivo inhibition of Medullary thyroid carcinoma cells by kinase inhibitors Sunitinib and Vandetanib
- Author(s)
  川井久美、山田徳香、村上秀樹、佐賀信介、高橋雅英
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460682
[Presentation] MEN2A型変異RETを有する甲状腺髄様癌細胞におけるチロシンキナーゼ阻害薬の効果の検討
- Author(s)
  舩戸連嗣、橋本克訓、川井久美
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30 – 2015-05-02
- Data Source
  KAKENHI-PROJECT-25460682
[Presentation] 徒然病理医絵巻
- Author(s)
  川井久美
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30 – 2015-05-02
- Data Source
  KAKENHI-PROJECT-25460682

1. MURAKAMI Hideki (90303619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Sato Mitsuo (70467281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 長谷哲成 (30621635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 湯川博 (30634646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 田中一大 (40809810)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 川口晃司 (10402611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KUROKAWA Kei (90399030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IWASHITA Toshihide (00283432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAGA Shinsuke (40144141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKAHASHI Yoshiyuki (40432273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MURAKUMO Yoshiki (40324438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. JIJIWA Mayumi (50378006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高橋雅英 (40183446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 芳川豊史 (00452334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 横井香平 (60378007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMADA Norika

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 山下依子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 豊國伸哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 森瀬昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAI Kumi 川井 久美

Research Projects

Research Products

Co-Researchers

Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transition

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutics that utilize driver oncogene-induced senescence

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Phosphoproteomic analysis of RET kinase signal in MTC model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and analysis of the stem cells and its differentiation in sympathetic neural crest cells and neuroblastoma cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New Tyrosine kinase inhibitor for thyroid medullary carcinoma treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多発性内分泌腫瘍症モデルマウスを用いた発がんの分子機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation and Characterization of Knockout Mice Targeting REV7 gene, which is involved in DNA damage tolerance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 病理と臨床 臨時増刊号 vol.34 癌の分子病理学 病理診断から治療標的探索まで2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 標準理学療法学・作業療法学 病理学4版2016

Author(s)

Total Pages

Publisher

Data Source

[Book] スタンダード病理学第４版2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] UHRF1, a Regulator of Methylation, as a Diagnostic and Prognostic Marker for Lung Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RET遺伝子研究の歩みと甲状腺癌2016

Author(s)

Journal Title

Data Source

[Journal Article] RET遺伝子研究の歩みと甲状腺癌2016

Author(s)

Journal Title

Data Source

[Journal Article] 多発性内分泌腫瘍症2016

Author(s)

Journal Title

Data Source

[Journal Article] Ovarian mucinous tumors arising from mature cystic teratomas--a molecular genetic approach for understanding the cellular origin.2014

Author(s)

KAWAI Kumi 川井久美

[Book] 病理と臨床臨時増刊号 vol.34 癌の分子病理学　病理診断から治療標的探索まで2016

[Book] 標準理学療法学・作業療法学　病理学4版2016