Hamano Yoshimitsu 濱野吉十

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HAMANO Yoshimitsu 濱野吉十

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Researcher Number	50372834
Other IDs
Affiliation (Current)	2026: 福井県立大学, 生物資源学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2025: 福井県立大学, 生物資源学部, 教授 2010 – 2014: 福井県立大学, 生物資源学部, 准教授 2011: 公立大学法人福井県立大学, 生物資源学部, 准教授 2009: Fukui Prefectural University, 生物資源学部, 講師 2008 – 2009: Fukui Prefectural University, 生物資源学部, 講師 2007: Fukui Prefectural University, 生物資源学部, 助教 2006: 福井県立大学, 生物資源学部, 助手
Review Section/Research Field	Principal Investigator Applied microbiology / Medium-sized Section 38:Agricultural chemistry and related fields / Science and Engineering / Basic Section 38030:Applied biochemistry-related / Basic Section 38020:Applied microbiology-related / Agricultural chemistry and related fields / Biomolecular chemistry / Bioorganic chemistry Except Principal Investigator Science and Engineering / Medium-sized Section 90:Biomedical engineering and related fields / Broad Section F / Medium-sized Section 38:Agricultural chemistry and related fields / Biomolecular chemistry
Keywords	Principal Investigator ポリリジン / ペプチド / 生合成 / 二次代謝産物 / 放線菌 / NRPS / 生合成遺伝子 / 細胞膜透過性ペプチド / ポリカチオン / CPP … More / 細胞膜透過性 / 抗生物質 / 生理活性 / 生体膜透過性 / 生体膜 / tRNA / 2次代謝産物 / ペプチド合成酵素 / Streptomyces albulus / アミノ酸ホモポリマー / 生体膜透過性ペプチド / 中分子創薬 / 経口投与 / バイオ医薬品 / インスリン / タンパク質 / 抗体 / 膜透過性 / 微生物 / 蛋白質 / 透過性 / 有機化学 / 応用微生物 / アミノ酸ポリマー / cell penetrating peptide / ペプチド結合 / リジン生合成 / アミノ酸生合成 / アデニル化 / 物質生産 / プロモーター / 発現系 / ATP / 発現ベクター / 酵素 / ストレプトスリシン / Stretomyces albulus / 非リボソームペプチド合成酵素 / ポリアミド … More Except Principal Investigator 生合成 / 異性化酵素 / 異性化 / ラッソペプチド / ペプチドエピメラーゼ / ポリグルタミン酸 / リボソームペプチド / ペプチドグリカン / エピメラーゼ / ペプチド / 生物分子科学 / 天然物化学 / 生合成工学 / 合成生物学 / 生合成リデザイン / シュードペプチド / 放線菌 / シグナル伝達 / がん / 炎症 / 天然有機化合物 / （シュード）ペプチド / グルタミン酸エピメラーゼ / γ-ポリグルタミン酸 / タンパク質 / 生物分子化学 / ケトメミシン / ATP-grasp / カルボニルメチレン / ペプチドリガーゼ / カルボニルメチレン構造 / シュードトリペプチド / ATP-grasp ligase Less

Direct transduction of proteins, enzymes, and antibodies into microbial cellsPrincipal Investigator
- Principal Investigator
  
  濱野吉十
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Fukui Prefectural University
生物活性中高分子の革新的細胞内送達技術による細胞生理機能の制御Principal Investigator
- Principal Investigator
  
  濱野吉十
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Fukui Prefectural University
新規細胞内抗体送達技術を用いた革新的抗炎症療法の開発
- Principal Investigator
  
  谷口浩二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
Dissecting biosynthetic machineries of natural peptides leading to structural and functional diversities.
- Principal Investigator
  
  大利徹
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section F
- Research Institution
  Hokkaido University
Gastrointestinal absorption of bioactive peptides by natural PIECE conjugation methodPrincipal Investigator
- Principal Investigator
  
  Hamano Yoshimitsu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Fukui Prefectural University
New drug modalities with hydrophilic mid-size peptides from microorganismsPrincipal Investigator
- Principal Investigator
  
  Hamano Yoshimitsu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Fukui Prefectural University
Bacterial CPP-mediated internalization of antibodies and proteinsPrincipal Investigator
- Principal Investigator
  
  Hamano Yoshimitsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Fukui Prefectural University
Dissecting reaction mechanisms of novel peptide epimerases
- Principal Investigator
  
  Dairi Tohru
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Hokkaido University
tRNA engineering for new peptide natural products in StreptomycetesPrincipal Investigator
- Principal Investigator
  
  HAMANO Yoshimitsu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Agricultural chemistry and related fields
- Research Institution
  Fukui Prefectural University
Redesigning Biosynthetic Machineries (Project Team)
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Biosynthetic redesign of small molecules aimed for the concurrent improvements of cell permeability and water solubilityPrincipal Investigator
- Principal Investigator
  
  Hamano Yoshimitsu
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Fukui Prefectural University
Cell-penetrating proteins generated by modification with naturally occurring polycationic polymerPrincipal Investigator
- Principal Investigator
  
  HAMANO Yoshimitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Fukui Prefectural University
Redesigning Biosynthetic Machineries (International Activity Support Team)
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Biosynthetic enzymes for streptothricin group antibioticPrincipal Investigator
- Principal Investigator
  
  Hamano Yoshimitsu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Fukui Prefectural University
Biosynthesis of the Carbonylmethylene Structure Found in a Class of Pseudotripeptides, Ketomemicins
- Principal Investigator
  
  Dairi Tohru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
アデニル化酵素の機能改変による新規ストレプトスリシン類縁体の創製Principal Investigator
- Principal Investigator
  
  濱野吉十
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Fukui Prefectural University
Lysine biosynthetic pathway in a Streptomyces strain producing polylysinePrincipal Investigator
- Principal Investigator
  
  HAMANO Yoshimitsu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Fukui Prefectural University
ＡＴＰ生産能が高いポリリジン生産放線菌を宿主とした有用物質生産Principal Investigator
- Principal Investigator
  
  濱野吉十
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Fukui Prefectural University
Improvement of the membrane permeability of compounds used by streptothricin biosynthetic enzymesPrincipal Investigator
- Principal Investigator
  
  HAMANO Yoshimitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Applied microbiology
- Research Institution
  Fukui Prefectural University
Functional analysis of amino-acid-homopolymer synthetasePrincipal Investigator
- Principal Investigator
  
  HAMANO Yoshimitsu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Fukui Prefectural University
アミノ酸ホモポリマー生合成遺伝子の取得とその機能改変による新規ポリマーの創製Principal Investigator
- Principal Investigator
  
  濱野吉十
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Fukui Prefectural University

[Book] 化学Vol.64, No.2, p72-732009
- Author(s)
  濱野吉十
- Total Pages
  1
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] Biosynthesis of lactacystin as a proteasome inhibitor2025
- Author(s)
  Tsunoda Takeshi、Furumura Shunkichi、Yamazaki Haruka、Maruyama Chitose、Hamano Yoshimitsu、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Communications Chemistry
  
  Volume: 8 Issue: 1 Pages: 1-8
- DOI
  10.1038/s42004-025-01406-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05122, KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-22H04976, KAKENHI-PROJECT-23K26838
[Journal Article] Substrate specificities of two ketosynthases in eukaryotic microalgal and prokaryotic marine bacterial DHA synthases2025
- Author(s)
  Ogata Kaito、Nakama Riku、Kobayashi Hiyu、Kawata Tomoya、Maruyama Chitose、Tsunoda Takeshi、Ujihara Tetsuro、Hamano Yoshimitsu、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 122 Issue: 12 Pages: 1-6
- DOI
  10.1073/pnas.2424450122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05122, KAKENHI-PROJECT-22H04976, KAKENHI-PROJECT-23K26838
[Journal Article] Phase transfer mechanisms of fluorophore-labeled cell-penetrating peptide ε-poly-l-α-lysine at liquid|liquid interfaces2023
- Author(s)
  Sakae Hiroki、Takeuchi Yamato、Maruyama Chitose、Hamano Yoshimitsu、Nagatani Hirohisa
- Journal Title
  
  Electrochimica Acta
  
  Volume: 462 Pages: 142769-142769
- DOI
  10.1016/j.electacta.2023.142769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K13773, KAKENHI-PROJECT-22K05412, KAKENHI-PROJECT-23K04804, KAKENHI-PROJECT-22K19157, KAKENHI-PLANNED-22H05122
[Journal Article] N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry2023
- Author(s)
  Wang Yung-Lin、Chang Chin-Yuan、Hsu Ning-Shian、Lo I-Wen、Lin Kuan-Hung、Chen Chun-Liang、Chang Chi-Fon、Wang Zhe-Chong、Ogasawara Yasushi、Dairi Tohru、Maruyama Chitose、Hamano Yoshimitsu、Li Tsung-Lin
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2528-2528
- DOI
  10.1038/s41467-023-38218-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05412, KAKENHI-PLANNED-22H05122, KAKENHI-PROJECT-22H04976
[Journal Article] Peptide epimerase-dehydratase complex responsible for biosynthesis of the linaridin class ribosomal peptides2023
- Author(s)
  Xiao Wanlu、Tsunoda Takeshi、Maruyama Chitose、Hamano Yoshimitsu、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 87 Issue: 11 Pages: 1316-1322
- DOI
  10.1093/bbb/zbad106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05412, KAKENHI-PLANNED-22H05122, KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-22H04976, KAKENHI-PROJECT-23K26838
[Journal Article] First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria2022
- Author(s)
  Takeuchi Yamato、Ushimaru Kazunori、Kaneda Kohei、Maruyama Chitose、Ito Takashi、Yamanaka Kazuya、Ogasawara Yasushi、Katano Hajime、Kato Yasuo、Dairi Tohru、Hamano Yoshimitsu
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1132-1132
- DOI
  10.1038/s42003-022-04110-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05403, KAKENHI-PLANNED-22H05122, KAKENHI-PROJECT-22H04976, KAKENHI-PROJECT-20H02918
[Journal Article] Molecular and mechanistic characterization of PddB, the first PLP-independent 2,4-diaminobutyric acid racemase discovered in an actinobacterial D-amino acid homopolymer biosynthesis2021
- Author(s)
  Kazuya Yamanaka, Ryo Ozaki, Yoshimitsu Hamano, Tadao Oikawa
- Journal Title
  
  Front. Microbiol.
  
  Volume: in press
- DOI
  10.3389/fmicb.2021.686023
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06445
[Journal Article] tRNA-dependent amide bond?forming enzymes in peptide natural product biosynthesis2020
- Author(s)
  Maruyama Chitose、Hamano Yoshimitsu
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 59 Pages: 164-171
- DOI
  10.1016/j.cbpa.2020.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05776, KAKENHI-PLANNED-16H06445
[Journal Article] C-Methylation of S-adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium2020
- Author(s)
  Maruyama Chitose、Chinone Yukiko、Sato Shusuke、Kudo Fumitaka、Ohsawa Kosuke、Kubota Junya、Hashimoto Junko、Kozone Ikuko、Doi Takayuki、Shin-ya Kazuo、Eguchi Tadashi、Hamano Yoshimitsu
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 5 Pages: 775-775
- DOI
  10.3390/biom10050775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05776, KAKENHI-PLANNED-16H06451, KAKENHI-PROJECT-19J11692, KAKENHI-PROJECT-18H02095, KAKENHI-PLANNED-16H06445
[Journal Article] The Stereocontrolled Biosynthesis of Mirror-Symmetric 2,4-Diaminobutyric Acid Homopolymers Is Critically Governed by Adenylation Activations2020
- Author(s)
  Yamanaka Kazuya、Fukumoto Hibiki、Takehara Munenori、Hamano Yoshimitsu、Oikawa Tadao
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 15 Issue: 7 Pages: 1964-1973
- DOI
  10.1021/acschembio.0c00321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06551, KAKENHI-PLANNED-16H06445
[Journal Article] In vitro characterization of MitE and MitB: Formation of N-acetylglucosaminyl-3-amino-5-hydroxybenzoyl-MmcB as a key intermediate in the biosynthesis of antitumor antibiotic mitomycins2019
- Author(s)
  Ogasawara Yasushi、Nakagawa Yo、Maruyama Chitose、Hamano Yoshimitsu、Dairi Tohru
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Issue: 16 Pages: 2076-2078
- DOI
  10.1016/j.bmcl.2019.07.009
- NAID
  120007132051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937
[Journal Article] Partition of amines and lysine oligomers between organic solvent and water under a controlled interfacial potential difference2018
- Author(s)
  Katano, H., Maruyama, M., Kuroda, Y., Uematsu, K., Maruyama, C., Hamano, Y.
- Journal Title
  
  J. Electroanal. Chem.
  
  Volume: 820 Pages: 97-102
- DOI
  10.1016/j.jelechem.2018.05.001
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06445, KAKENHI-PROJECT-16H03284
[Journal Article] Functional analysis of methyltransferases participating in streptothricin-related antibiotic biosynthesis2018
- Author(s)
  Niikura Haruka、Maruyama Chitose、Ogasawara Yasushi、Shin-ya Kazuo、Dairi Tohru、Hamano Yoshimitsu
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 125 Issue: 2 Pages: 148-154
- DOI
  10.1016/j.jbiosc.2017.09.004
- NAID
  40021471176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03110, KAKENHI-PLANNED-16H06452, KAKENHI-PLANNED-16H06445
[Journal Article] Promotion Effect of Streptothricin on a Glucose Oxidase Enzymatic Reaction and Its Application to a Colorimetric Assay2018
- Author(s)
  UEMATSU Kohei、UENO Takaaki、KAWASAKI Haruka、MARUYAMA Chitose、HAMANO Yoshimitsu、KATANO Hajime
- Journal Title
  
  Anal. Sci.
  
  Volume: 34 Issue: 2 Pages: 143-148
- DOI
  10.2116/analsci.34.143
- NAID
  130006341964
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14503, KAKENHI-PLANNED-16H06445
[Journal Article] Colorimetric Microtiter Plate Assay of Polycationic Aminoglycoside Antibiotics in Culture Broth Using Amaranth2017
- Author(s)
  H. Katano, Y. Kuroda, S. Taira, C. Maruyama, Y. Hamano
- Journal Title
  
  Anal. Sci.
  
  Volume: 33 Issue: 4 Pages: 499-504
- DOI
  10.2116/analsci.33.499
- NAID
  130005587977
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26410226, KAKENHI-PLANNED-16H06445
[Journal Article] Imaging mass spectrometry analysis of ubiquinol localization in the mouse brain following short-term administration2017
- Author(s)
  Tatsuta Yukina、Kasai Kazuaki、Maruyama Chitose、Hamano Yoshimitsu、Matsuo Kazuhiko、Katano Hajime、Taira Shu
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12990-12296
- DOI
  10.1038/s41598-017-13257-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K04890, KAKENHI-PLANNED-16H06445, KAKENHI-PROJECT-16H03284
[Journal Article] Antimicrobial Activity of ε-Poly-l-lysine after Forming a Water-Insoluble Complex with an Anionic Surfactant2017
- Author(s)
  Kazunori Ushimaru, Yoshimitsu Hamano, Hajime Katano
- Journal Title
  
  Biomacromolecules
  
  Volume: 18 Issue: 4 Pages: 1387-1392
- DOI
  10.1021/acs.biomac.7b00109
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J07756, KAKENHI-PROJECT-16K17961, KAKENHI-PLANNED-16H06445, KAKENHI-PROJECT-16H03284
[Journal Article] tRNA-dependent aminoacylation of an amino sugar intermediate in the biosynthesis of a streptothricin-related antibiotic2016
- Author(s)
  Maruyama, C., Niikura, H., Izumikawa, M., Hashimoto, J., Shin-ya, K., Komatsu, M., Ikeda, H., Kuroda, M., Sekizuka, T., Ishikawa, J., Hamano, M.
- Journal Title
  
  Appl. Environ. Microbiol.
  
  Volume: 82 Issue: 12 Pages: 3640-3648
- DOI
  10.1128/aem.00725-16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-15K14724
[Journal Article] 抗生物質ストレプトスリシンの修飾酵素と生合成酵素による毒性緩和2013
- Author(s)
  濱野吉十
- Journal Title
  
  バイオサイエンスとインダストリー(財団法人バイオインダストリー協会)
  
  Volume: Vol. 71,No. 1 Pages: 32-35
- NAID
  10031140299
- URL
  http://www.jba.or.jp/pc/archive/2013/vol71_no1.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22688007
[Journal Article] Colorimetric Determination of Pyrophosphate Anion and Its Application to Adenylation Enzyme Assay2013
- Author(s)
  Hajime Katano, Hiro Watanabe, Masahiro Takakuwa, Chitose Maruyama, and Yoshimitsu Hamano
- Journal Title
  
  Anal. Sci.
  
  Volume: 29 Issue: 11 Pages: 1095-1098
- DOI
  10.2116/analsci.29.1095
- NAID
  130004442169
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Data Source
  KAKENHI-PUBLICLY-25108720
[Journal Article] NRPSs and amide ligases producing homopoly(amino acid)s and homooligo(amino acid)s2013
- Author(s)
  濱野吉十
- Journal Title
  
  Natural Product Reports
  
  Volume: (In press) Issue: 8 Pages: 1087-1087
- DOI
  10.1039/c3np70025a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22688007
[Journal Article] 抗生物質ストレプトスリシンの修飾酵素と生合成酵素による毒性緩和2013
- Author(s)
  濱野　吉十
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 71 Pages: 32-35
- NAID
  10031140299
- Data Source
  KAKENHI-PROJECT-22688007
[Journal Article] A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis2012
- Author(s)
  Chitose Maruyama, Junya Toyoda, YasYasuo Kato, Miho Izumikawa, Motoki TakYasuo Kato, Miho Izumikawa, Motoki Takagi, Kazuo Shin-ya, Hajime Katano, Takashi Utagawa, and Yoshimitsu Hamano
- Journal Title
  
  Nature Chem. Biol
  
  Volume: 8 Issue: 9 Pages: 791-797
- DOI
  10.1038/nchembio.1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22688007, KAKENHI-PUBLICLY-23108520
[Journal Article] バイオプラスチック合成技術に利用可能な微生物由来酵素2010
- Author(s)
  濱野吉十
- Journal Title
  
  加工技術 Vol.45,No.4
  
  Pages: 27-34
- NAID
  40017079575
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] バイオプラスチック合成技術に利用可能な微生物由来酵素2010
- Author(s)
  濱野吉十
- Journal Title
  
  加工技術(繊維社) 45
  
  Pages: 239-239
- NAID
  40017079575
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] アミノ酸のホモポリマー化を触媒する新奇ペプチド合成酵素を発見2009
- Author(s)
  濱野吉十
- Journal Title
  
  科研費NEWS Vol.1,No.7
  
  Pages: 17-17
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] 抗菌物質の合成酵素を新たに発見!2009
- Author(s)
  濱野吉十
- Journal Title
  
  化学(化学同人) Vol.64,No.2
  
  Pages: 72-73
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] アミノ酸ホモポリマーを合成する新たなペプチド合成酵素2009
- Author(s)
  山中一也, 丸山千登勢, 高木博史, 濱野吉十
- Journal Title
  
  蛋白質・核酸・酵素(共立出版) Vol.54,No.11
  
  Pages: 1382-1388
- NAID
  40016708079
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] アミノ酸のホモポリマー化を触媒する新規ペプチド合成酵素2009
- Author(s)
  濱野吉十
- Journal Title
  
  酵素工学ニュース(酵素工学研究会) No.61
  
  Pages: 26-31
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] ε-ポリ-L-リジン合成酵素の反応メカニズムの解明2009
- Author(s)
  濱野吉十
- Journal Title
  
  バイオサイエンスとインダストリー(財団法人バイオインダストリー協会) Vol.67,No.7
  
  Pages: 338-341
- NAID
  10026194817
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] ε-poly-L-lysine dispersity is controlled by a highly unusual non-ribosomal peptide synthetase.2008
- Author(s)
  Kazuya Yamanaka*, Chitose Maruyama, Hiroshi Takagi, Yoshimitsu Hamano*
- Journal Title
  
  Nat. Chem. Biol. 4
  
  Pages: 766-772
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] A highly unusual non-ribosomal peptide synthase producing an amino-acid homopolymer
- Author(s)
  Kazuya Yamanaka, Chitose Maruyama, Hiroshi Takagi, Yoshimitsu Hamano
- Journal Title
  
  (投稿中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18780061
[Journal Article] Identification and analysis of anε-poly-L-lysine-degrading enzyme reveal the mechanism ofε-poly-L-lysine production and accumulation.
- Author(s)
  Kazuya Yamanaka, Naoko Kito, Yuuki Imokawa, Chitose Maruyama, Takashi Utagawa, Yoshimitsu Hamano
- Journal Title
  
  Appl. Environ. Microbiol (In press)
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] Biochemistry and enzymology ofε-poly-L-lysine biosynthesis
- Author(s)
  Yoshimitsu Hamano
- Journal Title
  
  Microbiology Monographs (Springer) (In press)
- Data Source
  KAKENHI-PROJECT-20780057
[Journal Article] Biotechnological production ofε-poly-L-lysine for food and medical applications
- Author(s)
  Kazuya Yamanaka, Yoshimitsu Hamano
- Journal Title
  
  Microbiology Monographs (Springer) (In press)
- Data Source
  KAKENHI-PROJECT-20780057
[Patent] 細胞膜透過性ポリカチオンイソペプチドを含む経口医薬組成物、ポリイオンコンプレックス複合体、その製造方法及び経口インスリン製剤2024
- Inventor(s)
  濱野吉十
- Industrial Property Rights Holder
  福井県立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-22K19157
[Patent] 細胞膜透過性ポリカチオンイソペプチドを含む経口医薬組成物、ポリイオンコンプレックス複合体、その製造方法及び経口インスリン製剤2023
- Inventor(s)
  濱野吉十
- Industrial Property Rights Holder
  福井県立大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-025687
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K19157
[Patent] クリック官能基をもつε-ポリ－L-リジン誘導体、その製法、及びその用途2018
- Inventor(s)
  濱野吉十、牛丸和乗
- Industrial Property Rights Holder
  福井県立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PLANNED-16H06445
[Patent] クリック官能基をもつε-ポリ－L-リジン誘導体、その製法、及びその用途2018
- Inventor(s)
  濱野吉十、牛丸和乗
- Industrial Property Rights Holder
  福井県立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03284
[Patent] クリック官能基をもつε-ポリ－L-リジン誘導体、その製法、及びその用途2017
- Inventor(s)
  濱野吉十、牛丸和乗
- Industrial Property Rights Holder
  福井県立大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-159849
- Filing Date
  2017
- Data Source
  KAKENHI-PLANNED-16H06445
[Patent] クリック官能基をもつε-ポリ－L-リジン誘導体、その製法、及びその用途2017
- Inventor(s)
  濱野吉十、牛丸和乗
- Industrial Property Rights Holder
  福井県立大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-159848
- Filing Date
  2017
- Data Source
  KAKENHI-PLANNED-16H06445
[Patent] 遺伝子組換えStreptomyces属放線菌による有用物質生産法2010
- Inventor(s)
  山中一也、濱野吉十
- Industrial Property Rights Holder
  チッソ株式会社、福井県立大学
- Filing Date
  2010-03-03
- Data Source
  KAKENHI-PROJECT-20780057
[Patent] 特許2010
- Inventor(s)
  濱野吉十, ほか
- Industrial Property Rights Holder
  福井県立大学, ほか
- Filing Date
  2010-03-03
- Data Source
  KAKENHI-PROJECT-20780057
[Patent] ポリアミノ酸合成酵素とそれをコードする遺伝子2007
- Inventor(s)
  山中一也濱野吉十
- Industrial Property Rights Holder
  チッソ(株)福井県立大
- Industrial Property Number
  2007-112078
- Filing Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-18780061
[Presentation] リボソーム翻訳系翻訳後修飾ペプチド生合成における新規修飾酵素の機能解析2024
- Author(s)
  角田毅、Wanlu Xia、山谷優花、中嶋優、丸山千登勢、森田一洋、濱野吉十、小笠原泰志、大利徹
- Organizer
  第66回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Novel heme protein hydroxylates 7-position of C-terminus Trp during lasso peptide RES701-2 biosynthesis2024
- Author(s)
  Takeshi Tsunoda, Yuka Yamaya, Yu Nakashima, Chitose Maruyama, Yoshimitsu Hamano, Hiroyuki Morita, Yasushi Ogasawara, Tohru Dairi
- Organizer
  5th European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Biosynthetic studies on 7-hydroxytryptophan containing lasso peptide RES701-22024
- Author(s)
  Yuka Yamaya, Takeshi Tsunoda, Yu Nakashima, Chitose Maruyama, Yoshimitsu Hamano, Hiroyuki Morita, Yasushi Ogasawara, Tohru Dairi,
- Organizer
  第61回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Overall biosynthetic pathways of lactacystin, an inhibitor of the proteasome2024
- Author(s)
  Takeshi Tsunoda, Shunkichi Furumura, Haruka Yamazaki, Chitose Maruyama, Yoshimitsu Hamano, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  Directing Biosynthesis VII
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 7-Hydroxytryptophanを有するlassoペプチドRes701-2の生合成研究2024
- Author(s)
  山谷優花、角田毅、中嶋優、丸山千登勢、濱野吉十、森田洋行、小笠原泰志、大利徹
- Organizer
  第38 回日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] PIECEを利用したタンパク質/ペプチド医薬の経口投与ドラッグデリバリー2023
- Author(s)
  鈴木海渡, 伊藤崇志, 片野肇, 長谷部文人, 丸山千登勢, 濱野吉十
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22K19157
[Presentation] 微細藻類由来DHA合成酵素のketosynthaseドメインの機能解析2023
- Author(s)
  尾形海斗、小林飛悠、佐藤康治、丸山千登勢、濱野吉十、小笠原泰志、大利徹
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Phenylalanine hydroxylase found in the resormycin biosynthetic enzymes2023
- Author(s)
  Chihiro Kishi, Yasushi Ogasawara, Kazuya Yamanaka, Tohru Dairi, Yoshimitsu Hamano, Chitose Maruyama
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] PIECEを利用したタンパク質/ペプチド医薬の経口投与ドラッグデリバリー2023
- Author(s)
  鈴木海渡、伊藤崇志、片野肇、長谷部文人、丸山千登勢、濱野吉十
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-22K19157
[Presentation] Resormycin生合成酵素群より見出したphenylalanine水酸化酵素の機能解析2023
- Author(s)
  岸千紘、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] ε-poly-L-α-lysine による従来型CPP-タンパク質コンジュゲートの細胞膜透過性改善2023
- Author(s)
  武内大和, 長谷部文人, 丸山千登勢, 濱野吉十
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] ε-poly-L-α-lysine-doxorubicinコンジュゲートを用いたDNA導入技術の開発2023
- Author(s)
  山中雅喜, 小倉知也, 武内大和, 長谷部文人, 丸山千登勢, 濱野吉十
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] 抗生物質resormycinが有するβ-homolysineの生合成機構の解明2023
- Author(s)
  今堀千咲、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] β-lysine oligopeptides chain enhances intracellular uptake of streptothricin2023
- Author(s)
  Yoshimitsu Hamano
- Organizer
  4th International Conference on Natural Products Discovery and Development in the Genomic Era, SIMB
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] ポリカチオンイソペプチド修飾した中分子ペプチドの細胞膜透過性と生理活性の評価2023
- Author(s)
  小倉知也, 鈴木海渡, 武内大和, 長谷部文人, 丸山千登勢, 濱野吉十
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] Resormycin 生合成遺伝子群に見出した Phenylalanine 修飾酵素の機能解析2022
- Author(s)
  岸千紘、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 抗生物質 resormycin が有するβ-homolysine の生合成機構の解明2022
- Author(s)
  今堀千咲、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Biosynthesis and cell-penetrating activity of polycationic homopoly(amino acid)s2022
- Author(s)
  Yoshimitsu Hamano
- Organizer
  19th International Symposium on the Biology of Actinomycetes (ISBA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] ε-poly-L-lysineによるCPP修飾タンパク質の細胞内送達促進2022
- Author(s)
  武内大和、長谷部文人、丸山千登勢、濱野吉十
- Organizer
  2022年度日本農芸化学会（オンライン）
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] ポリカチオンイソペプチド修飾した抗生物質ダプトマイシンの細胞膜透過性と生理活性の評価2021
- Author(s)
  小倉知也，鈴木海渡，武内大和，丸山千登勢，濱野吉十
- Organizer
  2021年度日本放線菌学会大会（オンライン）
- Data Source
  KAKENHI-PROJECT-20K21284
[Presentation] ポリカチオンイソペプチド修飾した抗生物質バシトラシンの細胞膜透過性と生理活性の評価2021
- Author(s)
  鈴木海渡，小倉知也，武内大和，丸山千登勢，濱野吉十
- Organizer
  2021年度日本放線菌学会大会（オンライン）
- Data Source
  KAKENHI-PROJECT-20K21284
[Presentation] 微生物由来浦ポリカチオンペプチドを利用したタンパク質の細胞内送達2021
- Author(s)
  武内大和，牛丸和乗，兼田康平，丸山千登勢，濱野吉十
- Organizer
  2021年度日本放線菌学会大会（オンライン）
- Data Source
  KAKENHI-PROJECT-20H02918
[Presentation] 細胞膜透過に寄与する抗生物質 streptothricinのoligo(β-Lys)構造2020
- Author(s)
  兼田康平，武内大和，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2020年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 抗生物質resormycin生合成遺伝子群の同定および機能解析2020
- Author(s)
  茅根千湖，山中一也，五十嵐雅之，濱野吉十，丸山千登勢
- Organizer
  2020年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] In vitro characterization of early steps in the biosynthesis of antitumor antibiotics mitomycins2020
- Author(s)
  Y. Ogasawara, Y. Nakagawa, C. Maruyama, Y. Hamano, and T. Dairi
- Organizer
  3rd International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ε-poly-L-lysine修飾による抗体の細胞内送達法の確立2020
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2020年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性高分子のepsilon-poly-L-lysine修飾による細胞内送達法の確立2019
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  日本生物工学会2019年度大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 放線菌由来1-aminocyclopropane-1-carboxylic acid合成酵素の同定および酵素学的諸性質2019
- Author(s)
  茅根千湖，橋本絢子，小曽根郁子，新家一男，濱野吉十，丸山千登勢
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Chemical modification of the bioactive small molecules with oligo(β-Lys) for improving cell membrane permeability and water solubility2019
- Author(s)
  Kohei Kaneda, Chitose Maruyama, Yamato Takeuchi, Yasuo Kato, Yoshimitsu Hamano
- Organizer
  The 4th A3 Foresight Symposium on Chemical & Synthetic Biology of Natural Products 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Polycationic peptides-discovery, biosynthesis, and application2019
- Author(s)
  Yoshimitsu Hamano
- Organizer
  The 4th A3 Foresight Symposium on Chemical & Synthetic Biology of Natural Products 2019 meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Chemical modification of the bioactive small molecules with ε-poly-L-lysine for improving cell membrane permeability and water solubility2019
- Author(s)
  Fumika Matsumura, Chitose Maruyama, Yamato Takeuchi, Yasuo Kato, Yoshimitsu Hamano
- Organizer
  The 4th A3 Foresight Symposium on Chemical & Synthetic Biology of Natural Products 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Intracellular Delivery of Macromolecules Modified with ε-poly-L-lysine2019
- Author(s)
  Yamato Takeushi, Chitose Maruyama, Yasuo Kato, Yoshimitsu Hamano
- Organizer
  The 4th A3 Foresight Symposium on Chemical & Synthetic Biology of Natural Products 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Substrate specificity of tRNA-dependent amide-bond forming enzyme2019
- Author(s)
  Yoshimitsu Hamano
- Organizer
  The 14th Asian Congress on Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 抗腫瘍抗生物質マイトマイシンの初期生合成機構のin vitro解析2019
- Author(s)
  中川陽、小笠原泰志、丸山千登勢、濱野吉十、大利徹
- Organizer
  2019年度（第34回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Substrate specificity of tRNA-dependent amide bond-forming enzyme2019
- Author(s)
  Yoshimitsu Hamano
- Organizer
  2nd China-Japan Joint Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] 微生物由来の天然ポリカチオンを利用した生体高分子の細胞内送達法2019
- Author(s)
  濱野吉十
- Organizer
  日本農芸化学会2019年度大会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-16H03284
[Presentation] 機能性高分子のε-poly-L-lysine修飾による細胞内送達法の確立2019
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Intracellular Delivery of Macromolecules Modified with ε-poly-L-lysine2019
- Author(s)
  Yamato Takeushi, Chitose Maruyama and Yoshimitsu Hamano
- Organizer
  The 14th Asian Congress on Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Biosynthesis and cell-penetrating activity of bacterial homopoly(amino acid)s2019
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Chemistrly department, The University of British Columbia
- Invited
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Identification and characterization of bacterial 1-aminocyclopropane-1-carboxylic acid synthase2019
- Author(s)
  Yukiko Chinone, Yoshimitsu Hamano, Junko Hashimoto, Ikuko Kozone, Kazuo Shin-ya, Chitose Maruyama
- Organizer
  The 4th A3 Foresight Symposium on Chemical & Synthetic Biology of Natural Products 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Identification and characterization of bacterial 1-aminocyclopropane-1-carboxylic acid synthase2019
- Author(s)
  Yukiko Chinone, Chitose Maruyama, Yoshimitsu Hamano
- Organizer
  The 14th Asian Congress on Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Substrate specificity of tRNA-dependent amide-bond forming enzyme2019
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Enzyme Engineering XXV,
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性高分子のε-poly-L-lysine修飾による細胞内送達法の確立2019
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2019年度日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 抗生物質resormycinの生合成遺伝子群の同定および機能解析2019
- Author(s)
  茅根千湖，山中一也，五十嵐雅之，濱野吉十，丸山千登勢
- Organizer
  2019年度日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 細胞膜透過に寄与する抗生物質streptothricinのoligo(β-Lys)構造2019
- Author(s)
  兼田康平，武内大和，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2019年度日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 微生物由来の天然ポリカチオンを利用した生体高分子の細胞内送達法2019
- Author(s)
  濱野　吉十
- Organizer
  日本農芸化学会2019年度大会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 生体膜透過性・水溶性の一挙改善を志向した機能性低分子化合物のoligo(beta-Lys)修飾2019
- Author(s)
  兼田康平，武内大和，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  日本生物工学会2019年度大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性分子のε-poly-L-lysine修飾による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2018年度日本農芸化学会中部支部183回例会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性低分子化合物のポリリジン化による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16H03284
[Presentation] 機能性低分子化合物のポリリジン化による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性分子のε-poly-L-lysine修飾による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  酵素工学研究会第80回講演会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性分子のε-poly-L-lysine修飾による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  酵素工学研究会第80回講演会
- Data Source
  KAKENHI-PROJECT-16H03284
[Presentation] 機能性分子のε-poly-L-lysine修飾による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2018年度日本農芸化学会中部支部183回例会
- Data Source
  KAKENHI-PROJECT-16H03284
[Presentation] Promiscuous reactivity of aminoacyl-tRNA-dependent enzyme2018
- Author(s)
  Chitose Maruyama, Kanki Matsuda, Haruka Niikura, Yasushi Ogasawara, Junko Hashimoto, Kazuo Shin-ya, Tohru Dairi, Yoshimitsu Hamano
- Organizer
  The 3rd A3 foresight symposium on Chemical & Synthetic Biology of Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] 機能性分子のε-poly-L-lysine修飾による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2018年度日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 機能性分子のε-poly-L-lysine修飾による生体膜透過性・水溶性の一挙改善2018
- Author(s)
  武内大和，牛丸和乗，加藤康夫，丸山千登勢，濱野吉十
- Organizer
  2018年度日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-16H03284
[Presentation] Substrate specificity of tRNA-dependent amide bond-forming enzyme2018
- Author(s)
  Yoshimitsu Hamano
- Organizer
  1st Japan-German Symposium Biosynthesis and Function of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Substrate specificity of tRNA-dependent amide bond-forming enzyme2018
- Author(s)
  Yoshimitsu Hamano
- Organizer
  9th International Congress on Biocatalysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Biosynthesis of streptothricin group antibiotics2018
- Author(s)
  Yoshimitsu Hamano
- Organizer
  The 3rd A3 foresight symposium on Chemical & Synthetic Biology of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Streptothricin類縁生合成遺伝子群に見出したaminoacyl-tRNA依存型ペプチド合成酵素における基質認識機構の解析2017
- Author(s)
  松田貫暉，丸山千登勢，橋本絢子，新家一男，濱野吉十
- Organizer
  日本農芸化学会中部支部第180回例会
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] streptothricin類縁抗生物質の生合成研究に見出したtRNA依存性ペプチド合成酵素2017
- Author(s)
  濱野吉十
- Organizer
  新学術領域研究（研究領域提案型）生物合成系の再設計による複雑骨格機能分子の革新的創成科学，第1回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Amide-bond forming enzymes in the biosynthesis of streptothricin group antibiotics2017
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Society of Industrial Microbiology and Biotechnology (SIMB) 2017 meetin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Amide-bond Forming Enzymes in the Biosynthesis of Streptothricin Group Antibiotics2017
- Author(s)
  Yoshimitsu Hamano
- Organizer
  9th US-Japan Seminar on the Biosyntheis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Amide-bond forming enzymes in the biosynthesis of streptothricin group antibiotics2017
- Author(s)
  Yoshimitsu Hamano
- Organizer
  1st US-China Seminar on the Biosyntheis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Streptothricin類縁生合成遺伝子群に見出したaminoacyl-tRNA依存型ペプチド合成酵素における基質認識機構の解析2017
- Author(s)
  丸山千登勢，松田貫暉，橋本絢子，新家一男，濱野吉十
- Organizer
  2017年度日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-17K19243
[Presentation] Amide-bond forming enzymes in the biosynthesis of streptothricin group antibiotics2017
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Society of Industrial Microbiology and Biotechnology (SIMB) 2017 meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Amide-bond Forming Enzymes in the Biosynthesis of Streptothricin Group Antibiotics2017
- Author(s)
  Yoshimitsu Hamano
- Organizer
  9th US-Japan Seminar on the Biosyntheis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] streptothricin類縁抗生物質の生合成研究に見出したtRNA依存性ペプチド合成酵素2017
- Author(s)
  濱野吉十
- Organizer
  新学術領域研究（研究領域提案型）生物合成系の再設計による複雑骨格機能分子の革新的創成科学，第1回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] 膜透過性・水溶性の一挙改善を志向した新規機能性低分子の生合成リデザイン2017
- Author(s)
  濱野吉十
- Organizer
  新学術領域研究（研究領域提案型）生物合成系の再設計による複雑骨格機能分子の革新的創成科学，第3回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] Amide-bond forming enzymes in the biosynthesis of streptothricin group antibiotics2017
- Author(s)
  Yoshimitsu Hamano
- Organizer
  1st US-China Seminar on the Biosyntheis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06445
[Presentation] ストレプトスリシン類縁生合成遺伝子群に見出したAla-tRNAAla依存型ペプチド合成酵素の機能解析2016
- Author(s)
  松田貫暉，丸山千登勢，橋本絢子，新家一男，濱野吉十
- Organizer
  2016年度日本生物工学会大会
- Place of Presentation
  富山国際会議場（富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] ストレプトスリシン類縁生合成遺伝子群に見出したAla-tRNAAla依存型ペプチド合成酵素の機能解析2016
- Author(s)
  松田貫暉，丸山千登勢，橋本絢子，新家一男，濱野吉十
- Organizer
  2016年度日本放線菌学会大会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] 抗生物質BD-12生合成に関与するN-メチル基転移酵素の機能解析2016
- Author(s)
  新倉春香，丸山千登勢，新家一男，濱野吉十
- Organizer
  2016年度日本生物工学会大会
- Place of Presentation
  富山国際会議場（富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] ストレプトスリシン類縁生合成遺伝子群に見出したAla-tRNA依存型ペプチド合成酵素の機能解析2016
- Author(s)
  松田貫暉，丸山千登勢，橋本絢子，新家一男，濱野吉十
- Organizer
  日本農芸化学会・中部支部・第177回例会
- Place of Presentation
  名古屋大学農学部（名古屋市）
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] BD-12生合成におけるN-formimidoyl基転移酵素の酵素学的諸性質2016
- Author(s)
  新倉春香，丸山千登勢，泉川美穂，新家一男，濱野吉十
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌市コンベンションセンター（北海道、札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] 抗生物質BD-12生合成遺伝子の機能解析2015
- Author(s)
  新倉春香，丸山千登勢，泉川美穂，石川淳，池田治生，新家一男，濱野吉十
- Organizer
  2015年度日本放線菌学会大会
- Place of Presentation
  富山国際会議場（富山県、富山市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] 抗生物質BD-12生合成遺伝子の機能解析2015
- Author(s)
  新倉春香, 丸山千登勢, 泉川美穂, 石川淳, 池田治生, 新家一男, 濱野吉十
- Organizer
  2015年度日本生物工学会大会
- Place of Presentation
  城山観光ホテル（鹿児島県、鹿児島市）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15K14724
[Presentation] Streptothricin（ST）生合成酵素の基質特異性改変およびホモログ酵素による新規ST類縁化合物の創製2014
- Author(s)
  新倉春香，丸山千登勢，石川淳，片野肇，濱野吉十
- Organizer
  酵素工学研究会第71回講演会
- Place of Presentation
  福岡市
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] 抗生物質ストレプトスリシン生合成機構の解明2014
- Author(s)
  丸山千登勢，本山賢人，馬場信行，川畑球一，泉川美穂，増田裕一，小松護，土井隆行，新家一男，池田治生，濱野吉十
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京（明治大学）
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] 2. Streptothricin（ST）生合成酵素の基質特異性改変およびホモログ酵素による新規ST類縁化合物の創製2014
- Author(s)
  新倉春香，丸山千登勢，石川淳，片野肇，濱野吉十
- Organizer
  酵素工学研究会第71回講演会
- Place of Presentation
  福岡（九州大学）
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] ホモポリアミノ酸およびホモオリゴアミノ酸を合成する新奇ペプチド合成酵素の反応メカニズム2013
- Author(s)
  濱野吉十
- Organizer
  日本農芸化学会・中部支部・第168回例会
- Place of Presentation
  名古屋（名古屋大学）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] 抗生物質ストレプトスリシンの生合成に関する研究2013
- Author(s)
  濱野吉十
- Organizer
  酵素工学研究会第70回講演会
- Place of Presentation
  東京（東京大学）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] アデニル化酵素の機能改変による新規ストレプトスリシン類縁体の創製2013
- Author(s)
  濱野吉十
- Organizer
  第5回新学術領域生合成マシナリー公開シンポジウム
- Place of Presentation
  札幌（北海道大学）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] 生合成工学による抗生物質ストレプトスリシンの選択毒性改変2013
- Author(s)
  濱野吉十
- Organizer
  第65回日本生物工学会大会
- Place of Presentation
  広島（広島国際会議場）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] アデニル化酵素の機能改変による新規ストレプトスリシン類縁体の創製2013
- Author(s)
  濱野吉十
- Organizer
  科研費新学術領域第6回公開シンポジウム
- Place of Presentation
  千葉市（千葉大学）
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] Harnessing the streptothricin biosynthetic machinery2013
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Enzyme Engineering XXII
- Place of Presentation
  Toyama, Japan　（富山国際会議場）
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2012
- Author(s)
  濱野吉十
- Organizer
  東京大学薬学部講演会(招待講演)
- Place of Presentation
  東京
- Year and Date
  2012-02-09
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] Streptothricin(ST)生合成酵素群を利用した新規ST類縁化合物の創製2012
- Author(s)
  濱野吉十
- Organizer
  日本放線菌学会
- Place of Presentation
  東京
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2012
- Author(s)
  濱野吉十
- Organizer
  東京大学薬学部講演会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2012-02-09
- Data Source
  KAKENHI-PUBLICLY-23108520
[Presentation] A stand-alone adenylation domain catalyzes multiple amide-bond formation in streptothricin biosynthesis2012
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Society of Industrial Microbiology and Biotechnology (SIMB) 2012 meeting
- Place of Presentation
  Washington DC (US)
- Invited
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2012
- Author(s)
  濱野吉十
- Organizer
  東京大学薬学部講演会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-02-09
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] A stand-alone adenylation domain catalyzes multiple amide-bond formation in streptothricin biosynthesis2012
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Society of Industrial Microbiology and Biotechnology (SIMB) 2012 meeting
- Place of Presentation
  Washington DC (US)
- Year and Date
  2012-08-12
- Invited
- Data Source
  KAKENHI-PUBLICLY-23108520
[Presentation] Streptothricin（ST）生合成酵素群を利用した新規ST類縁化合物の創製2012
- Author(s)
  濱野　吉十
- Organizer
  2012年度日本放線菌学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2012
- Author(s)
  濱野吉十
- Organizer
  第2回生合成マシナリー札幌セミナー(招待講演)
- Place of Presentation
  札幌
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2012
- Author(s)
  濱野　吉十
- Organizer
  第２回生合成マシナリー札幌セミナー
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] A stand-alone adenylation domain catalyzes multiple amide-bond formation in streptothricin biosynthesis2012
- Author(s)
  濱野吉十
- Organizer
  Directing Biosynthesis III
- Place of Presentation
  Nottingham (UK)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] A stand-alone adenylation domain catalyzes multiple amide-bond formation in streptothricin biosynthesis2012
- Author(s)
  Yoshimitsu Hamano
- Organizer
  Directing Biosynthesis III
- Place of Presentation
  Nottingham (UK)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23108520
[Presentation] Streptothricin (ST)生合成酵素群を利用した新規化合物の創製2012
- Author(s)
  濱野　吉十
- Organizer
  第64回日本生物工学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PUBLICLY-23108520
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2012
- Author(s)
  濱野　吉十
- Organizer
  第２回生合成マシナリー札幌セミナー
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PUBLICLY-23108520
[Presentation] A stand-alone adenylation domain catalyzes multiple amide-bond formation in streptothricin biosynthesis2012
- Author(s)
  濱野吉十
- Organizer
  Society of Industrial Microbiology and Biotechnology (SIMB) 2012 meeting(招待講演)
- Place of Presentation
  Washington DC (US)
- Year and Date
  2012-08-12
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] Streptothricin (ST)生合成酵素群を利用した新規化合物の創製2012
- Author(s)
  濱野　吉十
- Organizer
  第64回日本生物工学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] Streptothricin (ST)生合成酵素群を利用した新規化合物の創製2012
- Author(s)
  濱野吉十
- Organizer
  日本生物工学会
- Place of Presentation
  神戸
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] Unusual non-ribosomal peptide synthetases producing amino-acid homopolymers2010
- Author(s)
  濱野吉十
- Place of Presentation
  ハワイ(アメリカ)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] ε-Poly-L-lysine(ε-PL)合成酵素の変異解析2010
- Author(s)
  鬼頭奈央子、山中一也、喜多彰洋, 丸山千登勢, 濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] アミノ酸のホモポリマー化を触媒する新規ペプチド合成酵素(シンポジウム)2010
- Author(s)
  濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ホモポリアミノ酸構造を有する天然生理活性物質の生合成機構と有用物質生産への展開2010
- Author(s)
  濱野吉十
- Organizer
  東京大学生物生産工学研究センターシンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] ホモポリアミノ酸の生合成に関する研究2010
- Author(s)
  濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] アミノ酸のホモポリマー化を触媒する新規ペプチド合成酵素2010
- Author(s)
  濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ε-PL合成酵素(Pls)におけるペプチド鎖長制御機構の解析2010
- Author(s)
  山中一也, 鬼頭奈央子, 喜多彰洋, 丸山千登勢, 濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ST生合成に関与するL-lysine 2, 3-aminomutaseの機能解析とβ-リジン合成2010
- Author(s)
  豊田順也, 丸山千登勢, 矢野愛佳, 濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 組換えPls大量発現系の確立2010
- Author(s)
  喜多彰洋, 丸山千登勢, 鬼頭奈央子, 山中一也, 濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ホモポリアミノ酸の生合成に関する研究(奨励賞受賞講演)2010
- Author(s)
  濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Unusual non-ribosomal peptide synthetases producing amino-acid homopolymers2010
- Author(s)
  濱野吉十, ほか
- Organizer
  Pacifichem 2010
- Place of Presentation
  ハワイ(ホノルル)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22688007
[Presentation] Streptothricin(ST)生合成遺伝子群の機能解析2010
- Author(s)
  丸山千登勢, 豊田順也, 矢野愛佳, 濱野吉十
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ε-poly-L-lysine dispersity is controlled by a highly unusual non-ribosomal peptide synthetase2009
- Author(s)
  Kazuya Yamanaka, Naoko Kito, Chitose Maruyama, Hiroshi Takagi, Yoshimitsu Hamano
- Organizer
  15th International Symposium on the Biology of Actinomycetes (ISBA)
- Place of Presentation
  Shanghai (CHINA)
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ε-Poly-L-lysine分解酵素遺伝子の同定および機能解析2009
- Author(s)
  山中一也, 鬼頭奈央子, 濱野吉十
- Organizer
  2009年度日本放線菌学会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptothricin生合成遺伝子群のクローニングと機能解析2009
- Author(s)
  丸山千登勢, 豊田順也, 矢野愛佳, 濱野吉十
- Organizer
  2009年度日本放線菌学会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ε-Poly-L-lysine合成酵素の変異解析2009
- Author(s)
  鬼頭奈央子, 山中一也, 丸山千登勢, 濱野吉十
- Organizer
  2009年度日本放線菌学会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptothricin(ST)生合成遺伝子群のクローニングおよび機能解析2009
- Author(s)
  丸山千登勢, 濱野吉十
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Biosynthesis of streptothricin2009
- Author(s)
  Chitose Maruyama, Junya Toyoda, Aika Yano, Yshimitsu Hamano
- Organizer
  15th International Symposium on the Biology of Actinomycetes (ISBA)
- Place of Presentation
  Shanghai (CHINA)
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] epsilon-Poly-L-lysine生合成における分解酵素の生理機能2009
- Author(s)
  山中一也, 鬼頭奈央子, 濱野吉十
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 組換えε-poly-L-lysine合成酵素(膜酵素)の発現系と簡易精製法の確立2009
- Author(s)
  山中一也, 喜多彰洋, 鬼頭奈央子, 丸山千登勢, 濱野吉十
- Organizer
  2009年度日本放線菌学会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] アミノ酸のホモポリマー化を触媒する新規ペプチド合成酵素～新規ホモポリアミノ酸合成への挑戦～2009
- Author(s)
  山中一也, 丸山千登勢, 高木博史, 濱野吉十
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ポリアミド系バイオプラスチックの新ツールε-Poly-L-lysine合成酵素の変異解析2009
- Author(s)
  鬼頭奈央子, 山中一也, 丸山千登勢, 濱野吉十
- Organizer
  第61回日本生物工学会大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 放線菌Saccharopolyspora erythraeaにおけるε-Poly-L-lysine合成酵素ホモログの機能解析2009
- Author(s)
  鬼頭奈央子, 山中一也, 濱野吉十
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptothricin生合成遺伝子群のクローニングと機能解析2009
- Author(s)
  丸山千登勢, 豊田順也, 矢野愛佳, 濱野吉十
- Organizer
  第61回日本生物工学会大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptothricin生合成遺伝子群におけるβ-リジンホモポリマー合成酵素遺伝子の同定2009
- Author(s)
  豊田順也, 丸山千登勢, 濱野吉十
- Organizer
  2009年度日本放線菌学会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] A highly unusual non-ribosomal peptide synthase producing an amino-acid homopolymer2008
- Author(s)
  濱野吉十
- Organizer
  7^<th> US-Japan Seminar on the Biosynthesis of Natural Products, Enzymology, Structural Biology, Drug Discovery
- Place of Presentation
  La Jolla, California, USA
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 抗菌性ホモポリアミノ酸ε-Poly-Llysine生合成酵素の精製, クローニング及び機能解析2008
- Author(s)
  鬼頭奈央子, 山中一也, 濱野吉十
- Organizer
  2008年度日本放線菌学会
- Place of Presentation
  山梨市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] ホモポリアミノ酸ε-Poly-L-lysineを合成する新奇非リボソームペプチド合成酵素2008
- Author(s)
  山中一也, 丸山千登勢, 高木博史, 濱野吉十
- Organizer
  第50回天然有機化合物討論会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] アミノ酸ホモポリマーepsilon-Poly-L-lysineを生合成する新奇非リボソームペプチド合成酵素2008
- Author(s)
  山中一也、丸山千登勢、高木博史、濱野吉十(発表者)
- Organizer
  日本農芸化学会2008年度大会(シンポジウム)
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-18780061
[Presentation] アミノ酸ホモポリマーepsilon-Poly-L-lysineを合成する新奇非リボソームペプチド合成酵素2008
- Author(s)
  濱野吉十
- Organizer
  第60回日本生物工学会大会(シンポジウム)
- Place of Presentation
  仙台市
- Year and Date
  2008-08-27
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptomyces albulusにおけるepsilon-Poly-L-lysine分解酵素遺伝子の同定2008
- Author(s)
  山中一也, 鬼頭奈央子, 濱野吉十
- Organizer
  第60回日本生物工学会大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 抗菌性ポリアミノ酸ε-Poly-L-lysine(ε-PL)生合成酵素の精製及びその酵素学的諸性質2008
- Author(s)
  山中一也(発表者)、濱野吉十
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-18780061
[Presentation] 抗菌性ポリアミノ酸ε-Poly-L-lysine(ε-PL)の生合成遺伝子のクローニングおよびその機能解析2008
- Author(s)
  山中一也、丸山千登勢、高木博史、濱野吉十(発表者)
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-18780061
[Presentation] A highly unusual non-ribosomal peptide synthase producing an amino-acid homopolymer2008
- Author(s)
  Kazuya Yamanaka, Chitose Maruyama, Hiroshi Takagi, Yoshimitsu Hamano
- Organizer
  7th US-Japan Seminar on the Biosynthesis of Natural Products, Enzymology, Structural Biology, Drug Discovery
- Place of Presentation
  La Jolla, California
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptothricin生合成遺伝子群のクローニングおよび機能解析2008
- Author(s)
  丸山千登勢, 濱野吉十
- Organizer
  第60回日本生物工学会大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] アミノ酸ホモポリマーepsilon-Poly -L-lysineを合成する新奇非リボソームペプチド合成酵素2008
- Author(s)
  山中一也, 丸山千登勢, 高木博史, 濱野吉十
- Organizer
  第60回日本生物工学会大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 放線菌Saccharopolyspora erythraeaにおけるepsilon-Poly-L-lysine合成酵素ホモログの機能解析2008
- Author(s)
  鬼頭奈央子, 山中一也, 濱野吉十
- Organizer
  第60回日本生物工学会大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] Streptothricin(ST)生合成遺伝子群のクローニングおよび機能解析2008
- Author(s)
  丸山千登勢, 濱野吉十
- Organizer
  2008年度日本放線菌学会
- Place of Presentation
  山梨市国際学会
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 放線菌Saccharopolyspora erythraeaにおけるε-Poly -L-lysine合成酵素ホモログの機能解析2008
- Author(s)
  鬼頭奈央子, 山中一也, 濱野吉十
- Organizer
  2008年度日本放線菌学会
- Place of Presentation
  山梨市
- Data Source
  KAKENHI-PROJECT-20780057
[Presentation] 抗菌性ポリアミノ酸ε-Poly-L-lysine(ε-PL)生合成酵素の精製及び酵素学的諸性質とin citro合成2007
- Author(s)
  山中一也(発表者)、濱野吉十
- Organizer
  第59回日本生物工学会大会
- Place of Presentation
  東広島市
- Data Source
  KAKENHI-PROJECT-18780061
[Presentation] 抗菌性ポリアミノ酸ε-Pol-L-lysine(ε-PL)の生合成遺伝子のクローニング2007
- Author(s)
  濱野吉十(発表者)、山中一也
- Organizer
  第59回日本生物工学会大会
- Place of Presentation
  東広島市
- Data Source
  KAKENHI-PROJECT-18780061
[Presentation] 抗生物質BD-12生合成遺伝子の機能解析
- Author(s)
  丸山千登勢，本山賢人，泉川美穂，小松護，池田治生，新家一男，濱野吉十
- Organizer
  2014年度日本生物工学会大会
- Place of Presentation
  札幌市
- Year and Date
  2014-09-09 – 2014-09-11
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] 抗生物質BD-12生合成遺伝子の機能解析
- Author(s)
  新倉春香，丸山千登勢，泉川美穂，石川淳，池田治生，新家一男，濱野吉十
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山市
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PUBLICLY-25108720
[Presentation] 抗生物質BD-12生合成遺伝子の機能解析
- Author(s)
  新倉春香，丸山千登勢，関塚剛史，黒田誠，石川淳，濱野吉十
- Organizer
  2014年度日本放線菌学会大会
- Place of Presentation
  つくば市
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PUBLICLY-25108720

1. Dairi Tohru (70264679)

# of Collaborated Projects: 5 results

# of Collaborated Products: 14 results
2. 丸山千登勢 (20452120)

# of Collaborated Projects: 5 results

# of Collaborated Products: 41 results
3. MORITA HIROYUKI (20416663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. OGASAWARA YASUSHI (20732986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. Abe Ikuro (40305496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 菅裕明 (00361668)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 梅野太輔 (00400812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 葛山智久 (30280952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 南篤志 (40507191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 渡辺賢二 (50360938)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 江口正 (60201365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 山崎真巳 (70222370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 脇本敏幸 (70363900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 池田治生 (90159632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. 山中一也 (30756870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
16. 谷口浩二 (20627020)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. SATOH YASUHARU (30360928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 尾仲宏康 (80315829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 坂江広基 (00779895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. TAMAI Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKEUCHI Yamato

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. NIIKURA Haruka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. MATSUDA Kanki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. KOMATSU Mamoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 加藤康夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 平修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hamano Yoshimitsu 濱野 吉十

HAMANO Yoshimitsu 濱野 吉十

Research Projects

Research Products

Co-Researchers

Direct transduction of proteins, enzymes, and antibodies into microbial cellsPrincipal Investigator

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生物活性中高分子の革新的細胞内送達技術による細胞生理機能の制御Principal Investigator

Principal Investigator

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新規細胞内抗体送達技術を用いた革新的抗炎症療法の開発

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Dissecting biosynthetic machineries of natural peptides leading to structural and functional diversities.

Principal Investigator

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Gastrointestinal absorption of bioactive peptides by natural PIECE conjugation methodPrincipal Investigator

Principal Investigator

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Review Section

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New drug modalities with hydrophilic mid-size peptides from microorganismsPrincipal Investigator

Principal Investigator

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Bacterial CPP-mediated internalization of antibodies and proteinsPrincipal Investigator

Principal Investigator

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Review Section

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Dissecting reaction mechanisms of novel peptide epimerases

Principal Investigator

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Review Section

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tRNA engineering for new peptide natural products in StreptomycetesPrincipal Investigator

Principal Investigator

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Redesigning Biosynthetic Machineries (Project Team)

Principal Investigator

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Biosynthetic redesign of small molecules aimed for the concurrent improvements of cell permeability and water solubilityPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Cell-penetrating proteins generated by modification with naturally occurring polycationic polymerPrincipal Investigator

Principal Investigator

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Research Institution

Redesigning Biosynthetic Machineries (International Activity Support Team)

Principal Investigator

Project Period (FY)

Hamano Yoshimitsu 濱野吉十

HAMANO Yoshimitsu 濱野吉十