SAKONO MASAFUMI 迫野昌文

Researcher Number	50391959
Other IDs
Affiliation *help	2014 – 2018 : 富山大学, 大学院理工学研究部(工学), 准教授 2017 : 富山大学, 大学院理工学研究部, 准教授 2011 – 2013 : 独立行政法人理化学研究所, 伊藤細胞制御化学研究室, 客員研究員 2006 : 独立行政法人理化学研究所, 前田ビアオ工学研究室, 訪問研究員 2005 : 独立行政法人理化学研究所, 前田バイオ工学研究室, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Biofunction/Bioprocess / Biofunction/Bioprocess / Basic Section 27040:Biofunction and bioprocess engineering-related Except Principal Investigator Chemistry / Science and Engineering
Keywords	Principal Investigator アミロイド / ハイドロゲル / 糖鎖 / DNAアプタマー / 環境応答性分子 / コンジュゲート / 遺伝子検査 / TALE / レクチン / DNA結合タンパク質 … More Except Principal Investigator 糖タンパク質 / 糖脂質 / 糖質関連化学・糖鎖工学 / 脂質 / 生体分子 / 糖 / 小胞体 / 蛋白質 Less

TALEの高いDNA配列認識特性を利用した遺伝子変異検査法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  迫野昌文
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  University of Toyama
Chemical Biology of ER Related Glycan ModificationsOngoing
- Principal Investigator
  
  伊藤幸成
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Institute of Physical and Chemical Research
Development of novel glycan probe for monitoring molecular chaperone activity.Principal Investigator
- Principal Investigator
  
  SAKONO MASAFUMI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  University of Toyama
  Institute of Physical and Chemical Research
Chemical biology approach to ganglioside-induced amyloidosisPrincipal Investigator
- Principal Investigator
  
  SAKONO MASAFUMI
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research
DNA-脂質複合体を組込んだ分子集合体による新規分離・分析法の開発Principal Investigator
- Principal Investigator
  
  迫野昌文
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research

All 2016 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Hydrophobic Tagged Dihydrofolate Reductase for Creating Misfolded Glycoprotein Mimetics2016
- Author(s)
  Masakazu Hachisu, Akira Seko, Shusaku Daikoku, Yoichi Takeda, Masafumi Sakono, Yukishige Ito
- Journal Title
  
  ChemBioChem
  
  Volume : 17 Pages : 300-303
- DOI
  10.1002/cbic.201500595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25420844
[Journal Article] PDI family protein ERp29 forms 1:1 complex with lectin chaperone calreticulin.2014
- Author(s)
  Masafumi Sakono, Akira Seko, Yoichi Takeda, Yukishige Ito
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume : 452 Pages : 27-31
- DOI
  10.1016/j.bbrc.2014.08.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25420844
[Journal Article] Folding of Synthetic Homogeneous Glycoproteins in the Presence of a Glycoprotein Folding Sensor Enzyme2014
- Author(s)
  Dedola S, Izumi M, Makimura Y, Seko A, Kanamori A, Sakono M, Ito Y, Kajihara Y
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume : 53 Pages : 2883-2887
- DOI
  10.1002/anie.201309665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25650040, KAKENHI-PROJECT-25420844
[Journal Article] Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions.2014
- Author(s)
  Masafumi Sakono, Akira Seko, Yoichi Takeda, Jun-ichi Aikawa, Masakazu Hachisu, Akihiko Koizumi, Kohki Fujikawa, Yukishige Ito
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume : 1840 Pages : 2904-2913
- DOI
  10.1016/j.bbagen.2014.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25420844
[Journal Article] Parallel quantification of lectin-glycan interaction using ultrafiltration2013
- Author(s)
  Yoichi Takeda, Akira Seko, Masafumi Sakono, Masakazu Hachisu, Akihiko Koizumi, Kohki Fujikawa, Yukishige Ito
- Journal Title
  
  Carbohydrate Research
  
  Volume : 375 Pages : 112-117
- DOI
  10.1016/j.carres.2013.04.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25420844
[Journal Article] Formation of non-toxic Aβ fibrils by small heat shock protein under heat-stress condition2013
- Author(s)
  Masafumi Sakono, Arata Utsumi, Tamotsu Zako, Tetsuya Abe, Masafumi Yohda and Mizuo Maeda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume : 430 Pages : 1259-1264
- DOI
  10.1016/j.bbrc.2012.12.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23760758, KAKENHI-PROJECT-24570143
[Journal Article] Human Prefoldin Inhibits Amyloid-β(Aβ) Fibrillation and Contributes to Formation of Nontoxic AβAggregates2013
- Author(s)
  K.M. Sörgjerd, T. Zako, M. Sakono, P.C. Stirling, M.R. Leroux, T. Saito, P. Nilsson, M. Sekimoto, T.C.Saido, M. Maeda
- Journal Title
  
  Biochemistry
  
  Volume : 52 Pages : 3532-3542
- DOI
  10.1021/bi301705c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680039, KAKENHI-PROJECT-23760758, KAKENHI-PROJECT-24570143
[Journal Article] Biophysical properties of UDP-glucose:glycoprotein glucosyltransferase, a folding sensor enzyme in the ER, delineated by synthetic probes.2012
- Author(s)
  Masafumi Sakono, Akira Seko, Yoichi Takeda, Masakazu Hachisu, and Yukishige Ito
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume : 426 Pages : 504-510
- DOI
  10.1016/j.bbrc.2012.08.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23760758
[Journal Article] Chemical synthesis of intentionally misfolded homogeneous glycoprotein: a unique approach for the study of glycoprotein quality control.2012
- Author(s)
  Masayuki Izumi, Yutaka Makimura, Simone Dedola, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, and Yasuhiro Kajihara
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume : 134 Pages : 7238-7241
- DOI
  10.1021/ja3013177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23760758
[Journal Article] Cell interaction study of amyloid using luminescent conjugated polythiophene : Implication that amyloid cytotoxicity is correlated with prolonged cellular binding2012
- Author(s)
  Tamotsu Zako
- Journal Title
  
  ChemBioChem
  
  Volume : (in press) Pages : 358-363
- DOI
  10.1002/cbic.201100467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770117, KAKENHI-PROJECT-23760758
[Journal Article] Naked-eye detection of amyloid aggregates by gold nanoparticles conjugated with amyloid beta antibody2012
- Author(s)
  Masafumi Sakono
- Journal Title
  
  Analytical Sciences
  
  Volume : 28 Pages : 73-76
- DOI
  10.2116/analsci.28.73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770117, KAKENHI-PROJECT-23760758
[Journal Article] Amyloid oligomer detection by immobilized molecular chaperone2012
- Author(s)
  Sakono M. Zako T, Yohda M, Maeda M.
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume : 61 Pages : 28-33
- DOI
  10.1016/j.bej.2011.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370067, KAKENHI-PUBLICLY-22020011, KAKENHI-PROJECT-23760758
[Journal Article] Display of functionally active PHB depolymerase on Escherichia coli cell surface2012
- Author(s)
  Tomohiro Hiraishi, Koichi Yamashita, Masafumi Sakono, Jun Nakanishi, Tan Liu Tzea, Kumar Sudesh, Hideki Abe, and Mizuo Maeda
- Journal Title
  
  Macromolecular Bioscience
  
  Volume : 12 Pages : 218-224
- DOI
  10.1002/mabi.201100273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23760758, KAKENHI-PROJECT-24550180
[Journal Article] Immobilized insulin amyloid enhances cell adhesion and proliferation due to interaction with fibronectin2011
- Author(s)
  Masafumi Sakono, Shigenori Akiyama, Tamotsu Zako, Shujiro Sakaki, Tomonori Waku, Naoki Tanaka, Mizuo Maeda
- Journal Title
  
  Chemistry Letters
  
  Volume : 40 Pages : 315-317
- DOI
  10.1246/cl.2011.315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23760758
[Journal Article] Application of two morphologically different fibrillar and filamentous insulin amyloids as a biomaterial for cell culture surfaces2011
- Author(s)
  Masafumi Sakono
- Journal Title
  
  Reactive and Functional Polymers
  
  Volume : 71 Pages : 324-328
- DOI
  10.1016/j.reactfunctpolym.2010.10.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770117, KAKENHI-PROJECT-23760758
[Journal Article] Alpha casein micelles show not only molecular chaperone-like aggregation inhibition properties but also protein refolding activity from the denatured state2011
- Author(s)
  Masafumi Sakono, Konomi Motomura, Tatsuo Maruyama, Noriho Kamiya, Masahiro Goto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume : 404 Pages : 494-497
- DOI
  10.1016/j.bbrc.2010.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 合成糖鎖によるレクチン様分子シャペロンの基質認識機構の解明2016
- Author(s)
  迫野昌文
- Organizer
  第22回ペプチドフォーラム
- Place of Presentation
  金沢大学サテライト・プラザ
- Year and Date
  2016-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-25420844
[Presentation] 合成糖鎖基質を用いたカルネキシンおよびカルメギンのシャペロン活性の比較2013
- Author(s)
  迫野昌文、瀬古玲、武田陽一、八須匡和、小泉晶彦、藤川紘樹、伊藤幸成
- Organizer
  農芸化学会2013年度大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] Synthesis of Erythropoietin bearing high-mannose type oligosaccharide2013
- Author(s)
  Tatsuo Kiuchi, Yutaka Makimura, Ryo Okamoto, Masayuki Izumi, Akira Seko, Masafumi Sakono, Akiko Kanamori, Yukishige Ito, Yasuhiro Kajihara
- Organizer
  The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology
- Place of Presentation
  Wako
- Year and Date
  2013-07-01
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 合成基質を用いた糖タンパク質品質管理機構の解明2013
- Author(s)
  迫野昌文、瀬古玲、武田陽一、八須匡和、小泉晶彦、藤川絋樹、伊藤幸成
- Organizer
  化学工学会第78年会
- Place of Presentation
  大阪
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] Analysis of UGGT by using misfolded glycoprotein mimics2013
- Author(s)
  Masakazu Hachisu, Akira Seko, Shusaku Daikoku, Yoichi Takeda, Akihiko Koizumi, Kohki Fujikawa, Masafumi Sakono, Yukishige Ito
- Organizer
  The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology
- Place of Presentation
  Wako
- Year and Date
  2013-07-01
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 分子シャペロンによるアミロイドベータオリゴマーの検出2012
- Author(s)
  迫野昌文，座古保, 養王田正文, 前田瑞夫
- Organizer
  化学工学会第77年会
- Place of Presentation
  新宿
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] カルネキシンおよびカルメギンのレクチン様分子シャペロン活性の比較2012
- Author(s)
  迫野昌文、瀬古玲、武田陽一、八須匡和、小泉晶彦、藤川紘樹、伊藤幸成
- Organizer
  GlycoTOKYO2012
- Place of Presentation
  東京
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 分子シャペロンによるアミロイドベータオリゴマーの検出2012
- Author(s)
  迫野昌文、座古保、養王田正文、前田瑞夫
- Organizer
  化学工学会第77年会
- Place of Presentation
  東京
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 糖基質との相互作用に伴う"フォールディングセンサー" UDP-Glc:Glycoprotein Glucosyltransferase（UGGT）の構造変化に関する検討2012
- Author(s)
  迫野昌文、武田陽一、八須匡和、瀬古玲、伊藤幸成
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 糖基質との相互作用に伴う"フォールディングセンサー"UDP-Glc : Glycoprotein Glucosyltransferase(UGGT)の構造変化に関する検討2012
- Author(s)
  迫野昌文、武田陽一、八須匡和、瀬古玲、伊藤幸成
- Organizer
  農芸化学会2012年度大会
- Place of Presentation
  京都
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] カルネキシンおよびカルメギンのレクチン様分子シャペロン活性の相同性に関する検討2012
- Author(s)
  迫野昌文、瀬古玲、武田陽一、八須匡和、小泉晶彦、藤川紘樹、伊藤幸成
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Year and Date
  2012-09-17
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] Conformational Change of Folding Sensor Enzyme UDP-Glc : Glycoprotein Glucosyltransferase (UGGT) by Interaction with Carbohydrate Substrates2011
- Author(s)
  Masafumi Sakono, Yoichi Takeda, Masakazu Hachisu, Akira Seko, Yukishige Ito
- Organizer
  The 3rd Asian Communication for Glycobiology and Glycotechnology
- Place of Presentation
  Shnghai
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] 低毒性アミロイド様インスリン凝集体の構造特性2011
- Author(s)
  迫野昌文、小林隆宏、座古保、Lindgren Mikael、Nilsson Peter、Hammarstrom Per、前田瑞夫
- Organizer
  化学工学会第76年会
- Place of Presentation
  東京
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] "フォールディングセンサー"UDP-Glc : Glycoprotein Glucosyltransferase(UGGT)の基質認識に伴う構造変化に関する検討2011
- Author(s)
  迫野昌文、武田陽一、八須匡和、瀬古玲、伊藤幸成
- Organizer
  GlycoTOKYO2011
- Place of Presentation
  東京
- Year and Date
  2011-11-09
- Data Source
  KAKENHI-PROJECT-23760758
[Presentation] Conformational Change of Folding Sensor Enzyme UDP-Glc:Glycoprotein Glucosyltransferase (UGGT) by Interaction with Carbohydrate Substrates2011
- Author(s)
  Masafumi Sakono, Yoichi Takeda, Masakazu Hachisu, Akira Seko and Yukishige Ito
- Organizer
  3rd ACGG conference
- Place of Presentation
  中国　上海
- Data Source
  KAKENHI-PROJECT-23760758

1. 伊藤幸成 (80168385)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
2. 武田陽一 (20423973)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. 松尾一郎 (40342852)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 梶原康宏 (50275020)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 井原義人 (70263241)

# of Collaborated Projects : 1results

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6. 戸谷希一郎 (80360593)

# of Collaborated Projects : 1results

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7. 平林義雄 (90106435)

# of Collaborated Projects : 1results

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8. 座古保

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
9. 金森審子

# of Collaborated Projects : 0results

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10. 養王田正文

# of Collaborated Projects : 0results

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11. 平石知裕

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 斉藤貴志

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# of Collaborated Products : 1results

SAKONO MASAFUMI 迫野 昌文

Research Projects

Research Products

Co-Researchers

TALEの高いDNA配列認識特性を利用した遺伝子変異検査法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemical Biology of ER Related Glycan ModificationsOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel glycan probe for monitoring molecular chaperone activity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemical biology approach to ganglioside-induced amyloidosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA-脂質複合体を組込んだ分子集合体による新規分離・分析法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hydrophobic Tagged Dihydrofolate Reductase for Creating Misfolded Glycoprotein Mimetics2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PDI family protein ERp29 forms 1:1 complex with lectin chaperone calreticulin.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Folding of Synthetic Homogeneous Glycoproteins in the Presence of a Glycoprotein Folding Sensor Enzyme2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Parallel quantification of lectin-glycan interaction using ultrafiltration2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Formation of non-toxic Aβ fibrils by small heat shock protein under heat-stress condition2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Prefoldin Inhibits Amyloid-β(Aβ) Fibrillation and Contributes to Formation of Nontoxic AβAggregates2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biophysical properties of UDP-glucose:glycoprotein glucosyltransferase, a folding sensor enzyme in the ER, delineated by synthetic probes.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical synthesis of intentionally misfolded homogeneous glycoprotein: a unique approach for the study of glycoprotein quality control.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell interaction study of amyloid using luminescent conjugated polythiophene : Implication that amyloid cytotoxicity is correlated with prolonged cellular binding2012

SAKONO MASAFUMI 迫野昌文