Oonishi Hiroe 大西弘恵

… Alternative Names

Hireo Ohnishi 大西弘恵

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Researcher Number	50397634
Other IDs	https://orcid.org/0000-0003-3437-680X
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定講師
Affiliation (based on the past Project Information) *help	2021 – 2025: 京都大学, 医学研究科, 特定助教 2017 – 2021: 京都大学, 医学研究科, 研究員 2016 – 2017: 京都大学, 医学研究科, 特定助教 2016: 京都大学, 医学(系)研究科(研究院), 助教 2015: 京都大学, 医学(系)研究科(研究院), 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 蝸牛 / ヒトiPS細胞 / ゲノム編集 / オルガノイド / 分化誘導 / 発生 / 空間トランスクリプトーム / 平面極性 / 組換えマウス / 内耳蝸牛 … More / SVIP / 三次元構造 / 極性 / Carbonic anhydrase 13 / トランスクリプトーム解析 / 内耳感覚上皮細胞 / 内耳オルガノイド / iPS細胞 / 内耳 / 前庭 / 難聴モデル / 共培養 / シナプス形成 / 神経細胞 / 色素性乾皮症 / 内耳感覚上皮組織培養 / 聴神経 / 神経分化誘導 / 疾患特異的iPS細胞 … More Except Principal Investigator 内耳 / 難聴 / 感音難聴 / 再生 / 有毛細胞 / 免疫不全ラット / マクロファージ / 移植 / iPS細胞 / 気道上皮 / オルガノイド / 人工内耳 / 細胞移植 / 蝸牛 / 鼻腔粘膜 / 免疫学 / ヒトiPS細胞 / 網羅的発現解析 / タンパク質 / 線維化 / 声帯 / 前庭 / 分化転換 / 内耳発生 / ロボット手術 / iPS細胞移植 / 光刺激人工内耳 / 蝸牛神経 / 遺伝子 / 聴覚 / iPS / 気道上皮細胞 / 空間トランスクリプトーム / ヒトiPS細胞由来気道上皮移植 / 嗅上皮再生 / 免疫 / 瘢痕化 / 線維芽細胞 / 発生学 / 組織マクロファージ / エクソソーム / 聴性脳幹誘発反応 / アデノ随伴ウイルス / 遺伝子導入 / 光遺伝学 / ラセン神経節 / エピジェネティクス / 再生医療 / 血液迷路関門 / 光刺激 / トランスクリプトーム解析 / 線毛上皮細胞 / トランスクリプトーム / 気管 / バリア破壊 / CRISPR/CAS9 / オミクロン株 / ノックアウトスクリーニング / CRISPR/Cas9システム / SARS-CoV-2 Spikeタンパク質 / ヒトiPS細胞由来気道上皮移植ラット / COVID-19 / COVID-19 モデル動物 / Spikeタンパク質 / ヒトiPS細胞由来気道上皮 / シュードウイルス / 新型コロナウイルス / イメージング質量分析 / 発生 / 気道線維化病変 / 瘢痕 / 極性 / 喉頭 / 平衡障害 / 宇宙環境 / 弾性 / 微小重力 / 鳥類 / 蝸牛上皮 / 網羅的遺伝子解析 / 遺伝子発現 / 単一細胞 / 網羅的遺伝子発現解析 / トランスレーショナルリサーチ / 再生医学 / チャネルロドプシン / 蝸牛有毛細胞 / 聴力再生 / 間葉系幹細胞（MSC） / 聴神経（ラセン神経節細胞） / iPS細胞由来神経前駆細胞 / ヒト多能性幹細胞（iPS細胞） / ラセン神経節細胞 / 蝸牛神経（聴神経）（ / チャンネルロドプシン / 聴神経 / ヒト多能性幹細胞（iPS） / 遺伝学 / 細胞生物学 / 耳科学 / MYPT / 機能解析 / 新規変異 / リポジトリ / TRIOBP / 内耳機能 / 遺伝性難聴 / EPHA2 / POLD1 / MYO6 / OTOA / CLDN14 / DIAPH1 / 前庭再生 / 前庭動眼反射 / hNSC / ｈNSC / 移植治療 / 前庭障害 / ネトリン１ / 創薬 / インスリン様細胞増殖因子 / IGF-1 / 保護 / シナプス / インスリン様細胞増殖因子１ / 人工材料 / 軟骨細胞 / 分化誘導 / 筋細胞 Less

Spatiotemporal dynamics of diversity in the inner ear resident macrophages
- Principal Investigator
  
  岡野高之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Fujita Health University
Transplantation of human iPS cell-derived olfactory epithelium and investigation of improving engraftment efficiency to restore function
- Principal Investigator
  
  桑田文彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Analysis of the mechanism of cochlear planar polarity formation by spatial transcriptome analysisPrincipal Investigator
- Principal Investigator
  
  大西弘恵
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
血液迷路関門（BLB）障害による平衡障害の病態解明と新規治療法の開発
- Principal Investigator
  
  田浦晶子
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Aino University
マクロファージ動態制御による声帯線維化予防技術開発
- Principal Investigator
  
  岸本曜
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Generation of the transplantation model of human iPS cell-derived airway epithelial sheet into nasal cavity
- Principal Investigator
  
  北田有史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
ヒトiPS細胞由来気道上皮細胞移植における生着効率向上因子の探索
- Principal Investigator
  
  桑田文彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
光刺激人工内耳技術とiPS細胞移植蝸牛神経再生の融合による新規難聴治療法の開発
- Principal Investigator
  
  伊藤壽一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Elucidation of inner ear development using multi-omics
- Principal Investigator
  
  山本典生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kobe City Medical Center General Hospital(First Clinical Division, Second Clinical Division, Third
光刺激人工内耳が加速させる細胞移植と分化転換からの蝸牛神経再生による新規難聴治療
- Principal Investigator
  
  西村幸司
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
  Teikyo University
内耳由来エクソソームを応用した血中miRNAによる内耳疾患予測へのアプローチ
- Principal Investigator
  
  谷口美玲
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Diversity and Alteration of the phenotype of cochlear resident macrophates during development
- Principal Investigator
  
  岡野高之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Fujita Health University
ヒト多能性幹細胞（iPS細胞）由来内耳オルガノイドの内耳移植による内耳再生研究
- Principal Investigator
  
  藤野清大
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Shiga General Hospital Clinical Research Center
内耳蝸牛三次元構造形成メカニズムの解明と蝸牛型オルガノイド作製への応用Principal Investigator
- Principal Investigator
  
  大西弘恵
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Elucidation of the cochlear development and inner ear pathology with imaging mass-spectrometry for the treatment of sensorineural hearing loss
- Principal Investigator
  
  山本典生
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kobe City Medical Center General Hospital(First Clinical Division, Second Clinical Division, Third
  Kyoto University
Elucidation of the mechanisms of SARS-CoV-2 infection and airway epithelial barrier disruption
- Principal Investigator
  
  Omori Koichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Mechanisms for the initial process of hair cell regeneration in avian inner ears
- Principal Investigator
  
  Nakagawa Takayuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
宇宙環境における内耳前庭の発生維持とバイオメカニクス
- Principal Investigator
  
  田浦晶子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Aino University
Development of novel therapeutic strategy for upper airway fibrotic lesions by controlling macrophage polarity
- Principal Investigator
  
  Kishimoto Yo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Elucidation of the develpmental mechanism of the cochlear sensory epithelia based on the single cell analysis
- Principal Investigator
  
  Yamamoto Norio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Analyses of the mechanisms for development of sensory epithelia in cochleae and vestibula and application to generating the model for deafness using hiPSCPrincipal Investigator
- Principal Investigator
  
  Ohnishi Hiroe
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Roles of IGF-1-Netrin axis in the cochlea
- Principal Investigator
  
  Nakagawa Takayuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kyoto University
Development of new therapy for balance disorders
- Principal Investigator
  
  Taura Akiko
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Aino University
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
The comprehesive analysis of human hereditary deafness
- Principal Investigator
  
  Kitajiri Shin-ichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Shinshu University
Development of a new treatment method for hearing loss by fusing cochlear implant technology and cochlear nerve regeneration
- Principal Investigator
  
  ITO JUICHI
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Research Institute, Shiga Medical Center
Elucidation of pathogenic mechanisms of sensorineural hearing loss and establishment of disease model using XP-A patient-derived iPS cellsPrincipal Investigator
- Principal Investigator
  
  Hireo Ohnishi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kyoto University
Development of regenerative medicine for head and neck tissues using murine and human iPS cells
- Principal Investigator
  
  Omori Koichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kyoto University
  Fukushima Medical University

All 2024 2023 2022 2021 2019 2017 2016

All Journal Article Presentation Book

[Book] 「iPS細胞の安全・高品質な作製技術、第6章, 第4節ヒトiPS細胞からの前庭神経節細胞作製の開発」2016
- Author(s)
  田浦晶子、大西弘恵
- Total Pages
  494
- Publisher
  株式会社技術情報協会
- Data Source
  KAKENHI-PROJECT-15K10748
[Journal Article] Changes in the Proportion of Each Cell Type After hiPSC-Derived Airway Epithelia Transplantation2024
- Author(s)
  Kitano Masayuki、Hayashi Yasuyuki、Ohnishi Hiroe、Okuyama Hideaki、Yoshimatsu Masayoshi、Mizuno Keisuke、Kuwata Fumihiko、Tada Takeshi、Kishimoto Yo、Morita Satoshi、Omori Koichi
- Journal Title
  
  Cell Transplantation
  
  Volume: 33
- DOI
  10.1177/09636897241228026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09666, KAKENHI-PROJECT-21K19567
[Journal Article] Comparative Study of Immunodeficient Rat Strains in Engraftment of Human-Induced Pluripotent Stem Cell-Derived Airway Epithelia2024
- Author(s)
  Hayashi Yasuyuki、Ohnishi Hiroe、Kitano Masayuki、Kishimoto Yo、Takezawa Toshiaki、Okuyama Hideaki、Yoshimatsu Masayoshi、Kuwata Fumihiko、Tada Takeshi、Mizuno Keisuke、Omori Koichi
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 30 Issue: 3-4 Pages: 144-153
- DOI
  10.1089/ten.tea.2023.0214
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09666, KAKENHI-PROJECT-21K19567
[Journal Article] EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development2024
- Author(s)
  Kagoshima Hiroki、Ohnishi Hiroe、Yamamoto Ryosuke、Yasumoto Akiyoshi、Tona Yosuke、Nakagawa Takayuki、Omori Koichi、Yamamoto Norio
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 44 Issue: 7 Pages: e1060232023-e1060232023
- DOI
  10.1523/jneurosci.1060-23.2023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09628, KAKENHI-PROJECT-23K24493
[Journal Article] Laryngeal Cartilage Regeneration of Nude Rats by Transplantation of Mesenchymal Stem Cells Derived from Human-Induced Pluripotent Stem Cells2023
- Author(s)
  Mizuno Keisuke、Ohnishi Hiroe、Yoshimatsu Masayoshi、Zhao Chengzhu、Hayashi Yasuyuki、Kuwata Fumihiko、Kaba Shinji、Okuyama Hideaki、Kawai Yoshitaka、Hiwatashi Nao、Kishimoto Yo、Sakamoto Tatsunori、Ikeya Makoto、Omori Koichi
- Journal Title
  
  Cell Transplantation
  
  Volume: 32
- DOI
  10.1177/09636897231178460
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09666
[Journal Article] Transplantation of Induced Pluripotent Stem Cell-Derived Airway Epithelia with a Collagen Scaffold into the Nasal Cavity2023
- Author(s)
  Kitada Yuji、Ohnishi Hiroe、Yamamoto Norio、Kuwata Fumihiko、Kitano Masayuki、Mizuno Keisuke、Omori Koichi
- Journal Title
  
  Tissue Engineering Part C: Methods
  
  Volume: 29 Issue: 11 Pages: 526-534
- DOI
  10.1089/ten.tec.2023.0074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09666, KAKENHI-PROJECT-23K08961
[Journal Article] Stepwise fate conversion of supporting cells to sensory hair cells in the chick auditory epithelium2023
- Author(s)
  Matsunaga Mami、Yamamoto Ryosuke、Kita Tomoko、Ohnishi Hiroe、Yamamoto Norio、Okano Takayuki、Omori Koichi、Nakagawa Takayuki
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 2 Pages: 106046-106046
- DOI
  10.1016/j.isci.2023.106046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09708, KAKENHI-PROJECT-22K16899, KAKENHI-PROJECT-19K09867, KAKENHI-PROJECT-21K20964, KAKENHI-PROJECT-21K09628
[Journal Article] Peroxisome Proliferator-Activated Receptor-γ Agonist Attenuates Vocal Fold Fibrosis in Rats via Regulation of Macrophage Activation2022
- Author(s)
  Shinji Kaba, Yoshitaka Kawai, Yuki Tanigami, Hiroe Ohnishi, Tomoko Kita, Masayoshi Yoshimatsu, Koichi Omori, Yo Kishimoto
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 192(5) Issue: 5 Pages: 771-782
- DOI
  10.1016/j.ajpath.2022.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09730
[Journal Article] Insulin-like growth factor 1 promotes the extension of Tracheal Epithelium in an in Vitro Tracheal organ culture model2021
- Author(s)
  Kishimoto Ippei、Ohnishi Hiroe、Yamahara Kohei、Nakagawa Takayuki、Yamashita Masaru、Omori Koichi、Yamamoto Norio
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 48 Issue: 3 Pages: 441-450
- DOI
  10.1016/j.anl.2020.09.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09345, KAKENHI-PROJECT-20K20307, KAKENHI-PROJECT-21K09622
[Journal Article] In silico analysis of inner ear development using public whole embryonic body single-cell RNA-sequencing data.2021
- Author(s)
  Yamamoto R, Ohnishi H, Omori K, Yamamoto N
- Journal Title
  
  Dev Biol
  
  Volume: 469 Pages: 160-171
- DOI
  10.1016/j.ydbio.2020.10.009
- NAID
  120006938956
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20307, KAKENHI-PROJECT-19H03803, KAKENHI-PROJECT-20J14838
[Journal Article] 前庭再生医療研究の将来展望2019
- Author(s)
  5.田浦晶子、大西弘恵、西村幸司、扇田秀章、中川隆之、山本典生、岡野高之、大森孝一、伊藤壽一
- Journal Title
  
  Equilibrium Research
  
  Volume: -
- NAID
  130007687327
- Data Source
  KAKENHI-PROJECT-17K11349
[Journal Article] Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea pig cochleae.2016
- Author(s)
  Ishikawa M*, Ohnishi H*, Skerleva D, Sakamoto T, Yamamoto N, Hotta A, Ito J, Nakagawa T.
- Journal Title
  
  J Tissue Eng Regen Med.
  
  Volume: in press Issue: 6 Pages: 1-13
- DOI
  10.1002/term.2072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10748, KAKENHI-PROJECT-15K10749, KAKENHI-PROJECT-23229009, KAKENHI-PROJECT-20K20307
[Journal Article] 「前庭障害に対するiPS細胞移植の可能性」2016
- Author(s)
  田浦晶子　大西弘恵
- Journal Title
  
  月刊臨床神経科学　Clinical neurosciense
  
  Volume: 34 Pages: 1142-1144
- Data Source
  KAKENHI-PROJECT-15K10748
[Journal Article] Regenerative therapy for vestibular disorders using human induced pluripotent stem cells (iPSCs): neural differentiation of human iPSC-derived neural stem cells after in vitro transplantation into mouse vestibular epithelia.2016
- Author(s)
  Taura A, Nakashima N, Ohnishi H, Nakagawa T, Funabiki K, Ito J, Omori K.
- Journal Title
  
  Acta Otolaryngol.
  
  Volume: 136(10) Issue: 10 Pages: 999-1005
- DOI
  10.1080/00016489.2016.1183169
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26280064, KAKENHI-PROJECT-15K10748, KAKENHI-PROJECT-26506010, KAKENHI-PROJECT-16K15727
[Presentation] Expression of Ebf1 and Ebf3 in the Vestibule and Semicircular Canals During Mouse Development2024
- Author(s)
  Yamamoto Norio, Kagoshima Hiroki, Ohnishi Hiroe, Nakagawa Takayuki, Omori Koichi
- Organizer
  The 47th Annual Midwinter Meeting of Association for Research in Otolaryngology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24493
[Presentation] 免疫不全ラットへhiPSC由来気道上皮移植における移植前後の各種構成細胞の割合の変化の検討2024
- Author(s)
  北野正之、大西弘恵、林泰之、奧山英晃, 吉松誠芳, 水野敬介, 多田剛志, 岸本曜, 森田智視, 大森孝一
- Organizer
  第36回日本喉頭科学会総会学術講演会
- Data Source
  KAKENHI-PROJECT-21K19567
[Presentation] hiPSC由来気道上皮移植後の移植前後における各種構成細胞の割合の変化2024
- Author(s)
  大西弘恵、林泰之、北野正之、奧山英晃, 吉松誠芳, 水野敬介, 桑田文彦, 多田剛志, 岸本曜, 森田智視, 大森孝一
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K19567
[Presentation] ヒトiPS細胞由来気道上皮移植における免疫不全ラット系統の比較検討2024
- Author(s)
  林泰之、大西弘恵、岸本曜、大森孝一
- Organizer
  第36回日本喉頭科学会総会学術講演会
- Data Source
  KAKENHI-PROJECT-21K19567
[Presentation] hiPSC由来気道上皮移植後の移植前後における各種構成細胞の割合の変化2024
- Author(s)
  大西弘恵、林泰之、北野正之、奧山英晃, 吉松誠芳, 水野敬介, 桑田文彦, 多田剛志, 岸本曜, 森田智視, 大森孝一
- Organizer
  第23回　日本再生医利用学会総会
- Data Source
  KAKENHI-PROJECT-22K09666
[Presentation] Ebf1 Suppresses the Proliferation of the Cochlear Prosensory Domain and Forms the Scala Tympani and Spiral Limbus during the Development of the Inner Ear2023
- Author(s)
  Hiroki Kagoshima, Hiroe Ohnishi, Takayuki Nakagawa, Koichi Omori, Norio Yamamoto
- Organizer
  ARO 46th Annual MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24493
[Presentation] 分化マーカーとしての利用を目指した内耳局在遺伝子の解析2023
- Author(s)
  大西　弘恵
- Organizer
  第 22 回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K09628
[Presentation] EDNRB2: a marker gene for the intermediate cells during supporting cell-to-hair cell conversion in chick basilar papillae2023
- Author(s)
  Mami Matsunaga, Ryosuke Yamamoto, Marie Tekeuchi, Tomoko Kita, Hiroe Ohnishi, Norio Yamamoto, Takayuki Okano, Koichi Omori, Takayuki Nakagawa
- Organizer
  58th Inner Ear Biology Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09708
[Presentation] 演題名：遺伝性疾患による不可逆的機能障害に対する細胞移植治療の基盤技術確立のためのラット鼻腔粘膜へのヒトiPS細胞由来気道上皮細胞シート移植2023
- Author(s)
  北田有史、大西弘恵、山本典生、桑田文彦、北野正之、水野敬介、大森孝一
- Organizer
  第44回　日本炎症・再生学会
- Data Source
  KAKENHI-PROJECT-23K08961
[Presentation] Regeneration of cochlea by cell transplantation2023
- Author(s)
  Juichi Ito, Koji Nishimura, Hiroe Ohnishi, Akiko Taura, Hideaki Ogita
- Organizer
  CORLAS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09738
[Presentation] Regeneration of cochlea by cell transplantation2023
- Author(s)
  Juichi Ito, Koji Nishimura, Hiroe Ohnishi, Akiko Taura Hideaki Ogita
- Organizer
  CORLAS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09622
[Presentation] 転写因子Ebf1のマウス蝸牛感覚上皮領域決定と聴覚機能における役割2023
- Author(s)
  鹿子島大貴, 大西弘恵, 大森孝一, 山本典生
- Organizer
  第124回日本耳鼻咽喉科頭頸部外科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-23K24493
[Presentation] Ebf1 Suppresses the Proliferation of the Cochlear Prosensory Domain and Forms the Scala Tympani and Spiral Limbus during the Development of the Inner Ear2022
- Author(s)
  Hiroki Kagoshima, Hiroe Ohnishi, Takayuki Nakagawa, Koichi Omori, Norio Yamamoto
- Organizer
  46th Annual MidWinter Meeting of Association for Research in Otolaryngology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09708
[Presentation] Identification of the Cochlear Duct Progenitor Using Published Single Cell RNA-Sequencing Data2021
- Author(s)
  Ryosuke Yamamoto, Hiroe Ohnishi, Takayuki Nakagawa, Koichi Omori, Norio Yamamoto
- Organizer
  The Association for Research in Otolaryngology. The 44th Annual MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03803
[Presentation] 単一細胞RNAシークエンシング公開データを利用した蝸牛の発生機構の探究2021
- Author(s)
  山本亮介, 大西弘恵, 大森孝一, 山本典生
- Organizer
  第122回日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19H03803
[Presentation] マウス内耳発生過程における転写因子Ebfファミリーの機能解析2021
- Author(s)
  鹿子島大貴, 山本亮介, 大西弘恵, 大森孝一, 山本典生
- Organizer
  第122回日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19H03803
[Presentation] IGF-1 delayed age-related hearing loss in DBA/2J mice2019
- Author(s)
  Skerleva D, Iguchi F, Katsuno T, Ohnishi H, Yamamoto N, Ito J, Omori K, Nakagawa T
- Organizer
  42nd Annual Meeting of Association for Research in Otolaryngology Mid-winter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11325
[Presentation] Trial for Improvement of Hair Cell Induction Method from Human Induced Pluripotent Stem Cell2019
- Author(s)
  Ohnishi H, Skerleva D, Okuyama H, Miyamoto T, Matsuura S, Kirino K, Yamamoto N, Ito J, Omori K, Saito M, Tsukita K, Inoue H and Nakagawa T.
- Organizer
  Association for Research in Otolaryngology 42th MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09318
[Presentation] The transplantation of sphere-forming stem cells from the inner ear into cochlea.2019
- Author(s)
  Hideaki Ogita, Juichi Ito, Koji Nishimura, Hiroe Ohnishi, Akiko Taura
- Organizer
  IEB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20307
[Presentation] Improvement of otic induction from human induced pluripotent stem cell.2019
- Author(s)
  Hiroe Ohnishi, Juichi Ito, Norio Yamamoto, Koichi Omori, Takayuki Nakagawa
- Organizer
  IEB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20307
[Presentation] Trial for Improvement of Hair Cell Induction Method from Human Induced Pluripotent Stem Cell.2019
- Author(s)
  Ohnishi H, Skerleva D, Okuyama H, Miyamoto T, Matsuura S, Kirino K, Yamamoto N, Ito J, Omori K, Saito M, Tsukita K, Inoue H and Nakagawa T.
- Organizer
  Association for Research in Otolaryngology 42th MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10748
[Presentation] ヒトiPS細胞からの内耳有毛細胞誘導法改良の試み2019
- Author(s)
  大西弘恵、デシスラヴァスケルレヴァ、奥山英晃、宮本達雄、松浦伸也、桐野浩輔、山本典生、伊藤壽一、大森孝一、齋藤潤、月田香代子、井上治久、中川隆之.
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K09318
[Presentation] ヒトiPS細胞からの内耳有毛細胞誘導法改良の試み2019
- Author(s)
  大西弘恵、デシスラヴァスケルレヴァ、奥山英晃、宮本達雄、松浦伸也、桐野浩輔、山本典生、伊藤壽一、大森孝一、齋藤潤、月田香代子、井上治久、中川隆之.
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15K10748
[Presentation] The role of IGF1-related pathways in the aging of the ear2017
- Author(s)
  Skerleva D, Ohnishi H, Kita T, Katsuno T, Stoyanov St, Yamamoto N, Ito J, Omori K, Nakagawa T
- Organizer
  54th Workshop on Inner Ear Biology and Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11325
[Presentation] An Attempt to Establish In Vitro Model Using TRIOBP KO Induced Pluripotent Stem Cells2017
- Author(s)
  Hiroe Ohnishi、Shin-ichiro Kitajiri、Xiangxin Lou、Akiko Taura、Mirei Taniguchi、Fumi Ebisu、Tatsunori Sakamoto、Norio Yamamoto、Juichi Ito1、Koichi Omori、Takayuki Nakagawa
- Organizer
  1st International Symposium on Inner Ear Therapies, November 01-03, 2017. Marrakech, Morocco
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04345
[Presentation] ビトリゲル上でのヒトiPS細胞からの気道上皮細胞分化誘導2017
- Author(s)
  大西　弘恵、中村亮介、奥山英晃、竹澤俊明、後藤慎平、興梠陽平、小西聡史、山下勝、岸本曜、楯谷一郎、山本典生、中川隆之、大森孝一
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-09
- Data Source
  KAKENHI-PROJECT-26293371
[Presentation] ヒトiPS細胞から内耳有毛細胞様細胞を誘導するための段階的分化誘導法の検討2016
- Author(s)
  大西　弘恵、Desislava Skerleva、北尻　真一郎、坂本　達則、山本　典生、伊藤　壽一、中川　隆之
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K10748

1. Yamamoto Norio (70378644)

# of Collaborated Projects: 12 results

# of Collaborated Products: 17 results
2. 西村幸司 (20405765)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
3. Nakagawa Takayuki (50335270)

# of Collaborated Projects: 7 results

# of Collaborated Products: 14 results
4. Taura Akiko (70515345)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
5. ITO JUICHI (90176339)

# of Collaborated Projects: 7 results

# of Collaborated Products: 5 results
6. 扇田秀章 (20761274)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
7. Kishimoto Yo (80700517)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
8. 岡野高之 (60642931)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
9. 十名洋介 (80898073)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
10. 喜多知子 (20362519)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
11. Kitajiri Shin-ichiro (00532970)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
12. Omori Koichi (10233272)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
13. 宮本達雄 (40452627)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
14. 池川雅哉 (60381943)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. 桑田文彦 (20774459)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
16. 松本昌宏 (80773811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 北田有史 (50869584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
18. 今泉光雅 (30554422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 吉江進 (70705459)

# of Collaborated Projects: 1 results

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20. 石川正昭 (10813743)

# of Collaborated Projects: 1 results

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21. 宇佐美真一 (10184996)

# of Collaborated Projects: 1 results

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22. 西尾信哉 (70467166)

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23. 飯田慶 (00387961)

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24. 宮崎浩 (00263228)

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25. 中島則行 (80625468)

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26. 藤野清大 (50359832)

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27. 朝長啓造 (10301920)

# of Collaborated Projects: 1 results

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28. 水田匡信 (20777875)

# of Collaborated Projects: 1 results

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29. 竹澤俊明 (50301297)

# of Collaborated Projects: 1 results

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30. 吉川弥生 (00452350)

# of Collaborated Projects: 1 results

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31. 山田義博 (30252464)

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32. 松永麻美 (00599524)

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33. 小野宗範 (30422942)

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34. 谷口美玲 (80706713)

# of Collaborated Projects: 1 results

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35. 山口太郎 (30710701)

# of Collaborated Projects: 1 results

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36. 河合良隆 (50862223)

# of Collaborated Projects: 1 results

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37. YUBA shyunsuke

# of Collaborated Projects: 1 results

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38. MATSUDA toshirou

# of Collaborated Projects: 1 results

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39. 山下勝

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# of Collaborated Products: 1 results
40. 船曵和雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oonishi Hiroe 大西 弘恵

Hireo Ohnishi 大西 弘恵

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Analysis of the mechanism of cochlear planar polarity formation by spatial transcriptome analysisPrincipal Investigator

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内耳蝸牛三次元構造形成メカニズムの解明と蝸牛型オルガノイド作製への応用Principal Investigator

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Oonishi Hiroe 大西弘恵

Hireo Ohnishi 大西弘恵