Koyama Hiroko 古山浩子

… Alternative Names

KOYAMA Hiroko 古山浩子

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Researcher Number	50402160
Other IDs
Affiliation (Current)	2025: 岐阜大学, 工学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 岐阜大学, 工学部, 准教授 2017: 岐阜大学, 工学部, 助教 2014 – 2015: 岐阜大学, 大学院医学系研究科, 助教 2012 – 2015: 岐阜大学, 医学(系)研究科(研究院), 助教 2011: 岐阜大学, 大学院・医学系研究科, 助教 2010 – 2011: 岐阜大学, 医学系研究科, 助教 2009: 岐阜大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 37010:Bio-related chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry Except Principal Investigator Basic Section 52040:Radiological sciences-related / Cerebral neurosurgery / Medium-sized Section 52:General internal medicine and related fields / Basic Section 56010:Neurosurgery-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Radiation science / Biomolecular chemistry / Drug development chemistry
Keywords	Principal Investigator 脳内移行性 / PET / 11C標識α-ケトグルタル酸 / イソクエン酸脱水素酵素１ / 11C標識O6-ベンジルグアニン / MGMT / プロドラッグ / 11C標識分子プローブ / PETイメージング / 非環式レチノイド（4,5-ジデヒドロGGA） … More / 核内受容体 / 高い血液脳関門透過性 / PET脳イメージング / 非環式レチノイド / 血液脳関門透過性 / 脳イメージング / 11C標識 / 高速クロスカップリング / 非環式レチノイド（ペレチノイン） / 11C-標識法 / 高速C-[11C]メチル化 / 高速C-メチル化 / アルキル－アルキル間高速クロスカップリング反応 / 鈴木・宮浦反応 / パラジウム触媒 / ボロン化合物 / 高速反応 / アルキル－アルキル間クロスカップリング反応 / PETプローブ合成 … More Except Principal Investigator 陽電子断層撮像法 / PET / アルツハイマー病 / 脳腫瘍 / ミクログリア / 分子イメージング / IEDDA / 生体直交反応 / CSF1R / イメージング / 創薬 / 細胞トラッキング / 化合物 / 四重鎖らせん / ゲノム / コロニー刺激因子１ / 神経変性疾患 / Alzheimer's disease / microglia / RIPK1 / 11C標識分子プローブ / 脳腫瘍PETイメージング / 11C標識プローブ / α-ケトグルタル酸 / 遺伝子変異イソクエン酸脱水素酵素１ / O6-ベンジルグアニン / O6-メチルグアニン-DNA-トランスフェラーゼ / 神経炎症 / マイクログリア / 陽電子断層撮像 / MIRD法 / 被曝線量 / タウ蛋白 / アルツハイマー / マイクロドーズ試験 / イソプロテレノール / 高速クロスカップリング反応 / ギンセノシド / ギンゴライド / 認知症(脳機能)改善漢方薬成分 / クロスメタセシス反応 / 高速クロスカップリング / グルコース / PET分子プローブ / クロスメタセシス / 高速メチル化 / グルコーストランスポーター / 認知症改善薬ギンゴライド＆ギンセノシド / 11C,18F-標識化 / PETプローブ / 糖輸送体 / 脳移行性 / ギンゴライド＆ジンセノサイド / PET分子イメージング / 11C標識 / ギンコライド / プローブ / プロドラック / 天然物 / 薬剤送達 / 核酸療法 / 神経膠腫 / 治療予後 / 分子マーカー / 化学療法 / 薬物送達 / 分子標的薬 / ロボティクス / ナノテクノロジー / 核酸医療 / 分子標的 / 脳神経疾患 / 臨床応用 / 有機合成 / 分子 / PETトレーサー / MGMT / 分子イメーグング / 治療 / メチル化 / ヒストン / エピジェネテュクス / 癌幹細胞 / エピジェネティクス Less

Evaluation of a PET imaging ligand for microglia in Alzheimer's diseases
- Principal Investigator
  
  木村泰之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
Synthesis of functional PET probes targeting enzymes specifically expressed in gliomaPrincipal Investigator
- Principal Investigator
  
  古山浩子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Gifu University
The regulation of gene expression by targeting G4 quadriplex in brain tumors
- Principal Investigator
  
  夏目敦至
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Development of an in vivo cell tracking method using biological orthogonal reactions and PET
- Principal Investigator
  
  木村泰之
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Center for Geriatrics and Gerontology
Development of PET imaging of brain immunity as a biomarker for drug development to treat neurodegenerative diseases
- Principal Investigator
  
  KIMURA YASUYUKI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
Development of brain PET imaging using bioorthogonal reactions
- Principal Investigator
  
  Kimura Yasuyuki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Center for Geriatrics and Gerontology
Novel PET probe for brain tumor imaging targeting specifically expressed enzymes
- Principal Investigator
  
  Suzuki Masaaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  National Center for Geriatrics and Gerontology
PET imaging of microglia, a novel drug target for neurodegenerative diseases
- Principal Investigator
  
  Kimura Yasuyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
Synthesis of 11C-labeled acyclic retinoids with high brain permeabilityPrincipal Investigator
- Principal Investigator
  
  Koyama Hiroko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Gifu University
PET microdose study for finding appropriate dose of isoproterenol as a disease modifying treatment of dementia
- Principal Investigator
  
  Ito Kengo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Center for Geriatrics and Gerontology
Development of PET probes of neuroprotective molecular components in oriental medicines
- Principal Investigator
  
  SUZUKI Masaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  National Center for Geriatrics and Gerontology
Development of rapid C-methylation between two sp3-hybridized carbons for incorporation of short-lived positron-emitting 11C radionuclidePrincipal Investigator
- Principal Investigator
  
  Koyama Hiroko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Multimodal medical strategies by means of robotic technology according with molecular target imaging
- Principal Investigator
  
  Wakabayashi Toshihiko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Synthesis of glycosylated derivatives of ginkgolides and in vivo evaluation of those pharmacokinetics
- Principal Investigator
  
  ISHII Hideki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Radiological Sciences
  The Institute of Physical and Chemical Research
Chemical biology reprogramming epigenetic aberration in malignant brain tumors
- Principal Investigator
  
  NATSUME Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Development of molecular imaging tracers for anticancer drug resistant proteins
- Principal Investigator
  
  WAKABAYASHI Toshihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Synthesis and evaluation of a novel PET ligand, a GSK’963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain2023
- Author(s)
  Ikenuma Hiroshi、Ogata Aya、Koyama Hiroko、Ji Bin、Ishii Hideki、Yamada Takashi、Abe Junichiro、Seki Chie、Nagai Yuji、Ichise Masanori、Minamimoto Takafumi、Higuchi Makoto、Zhang Ming-Rong、Kato Takashi、Ito Kengo、Suzuki Masaaki、Kimura Yasuyuki
- Journal Title
  
  EJNMMI Radiopharmacy and Chemistry
  
  Volume: 8 Issue: 1 Pages: 31-31
- DOI
  10.1186/s41181-023-00217-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02876, KAKENHI-PROJECT-23K27558
[Journal Article] [11C]NCGG401, a novel PET ligand for imaging of colony stimulating factor 1 receptors2022
- Author(s)
  Ogata Aya、Ji Bin、Yamada Takashi、Hattori Saori、Abe Junichiro、Ikenuma Hiroshi、Ichise Masanori、Koyama Hiroko、Suzuki Masaaki、Kato Takashi、Ito Kengo、Kimura Yasuyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 65 Pages: 128704-128704
- DOI
  10.1016/j.bmcl.2022.128704
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Journal Article] Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents2020
- Author(s)
  Ogata Aya、Kimura Yasuyuki、Ikenuma Hiroshi、Yamada Takashi、Abe Junichiro、Koyama Hiroko、Suzuki Masaaki、Ichise Masanori、Kato Takashi、Ito Kengo
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: － Pages: 52-58
- DOI
  10.1016/j.nucmedbio.2020.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04269, KAKENHI-PROJECT-18K06575
[Journal Article] Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone2019
- Author(s)
  Ikenuma Hiroshi、Koyama Hiroko、Kajino Naoya、Kimura Yasuyuki、Ogata Aya、Abe Junichiro、Kawasumi Yasuhiro、Kato Takashi、Takashima Akihiko、Ito Kengo、Suzuki Masaaki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Issue: 16 Pages: 2107-2111
- DOI
  10.1016/j.bmcl.2019.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04269, KAKENHI-PROJECT-18K06575
[Journal Article] 21.Organozinc-aided, HMPA-free, stoichiometric three-component coupling for the general synthesis of prostaglandins and stable prostacyclin analogs with biological significance2019
- Author(s)
  Hiroko Koyama, Atsuto Izumiseki, Masaaki Suzuki
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 60 Issue: 22 Pages: 1467-1470
- DOI
  10.1016/j.tetlet.2019.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06575
[Journal Article] Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.2015
- Author(s)
  Soeda Y, Yoshikawa M, Almeida OF, Sumioka A, Maeda S, Osada H, Kondoh Y, Saito A, Miyasaka T, Kimura T, Suzuki M, Koyama H, Yoshiike Y, Sugimoto H, Ihara Y, Takashima A
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 10216-10216
- DOI
  10.1038/ncomms10216
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350976, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Efficient syntheses of [11C]zidovudine and its analogues by convenient one-pot palladium(0)-copper(I)co-mediated rapid C-[11C]methylation.2014
- Author(s)
  Zhouen Zhang, Hisashi Doi, Hiroko Koyama, Yasuyoshi Watanabe, Masaaki Suzuki
- Journal Title
  
  J. Label. Compd. Radiopharm.
  
  Volume: 57 Issue: 8 Pages: 540-549
- DOI
  10.1002/jlcr.3213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Pd(0)-mediated rapid cross-coupling reactions, the rapid C-[11C]methylations, revolutionally advancing the syntheses of short-lived PET molecular probes2014
- Author(s)
  Masaaki Suzuki, Hisashi Doi, Hiroko Koyama, Zhang Zhouen, Takamitsu Hosoya, Hirotaka Onoe, Yasuyoshi Watanabe
- Journal Title
  
  Chem. Rec.
  
  Volume: 14 Issue: 3 Pages: 516-541
- DOI
  10.1002/tcr.201400002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Synthesis of 11C-labeled retinoic acid, [11C]ATRA, via an alkenylboron precursor by Pd(0)-mediated rapid C-[11C]methylation2014
- Author(s)
  Masaaki Suzuki, Misato Takashima-Hirano, Hideki Ishii, Chika Watanabe, Kengo Sumi, Hiroko Koyama, Hisashi Doi,
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 15 Pages: 3622-3625
- DOI
  10.1016/j.bmcl.2014.05.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590156, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Evaluation of TlOH Effect for Pd0-Mediated Cross-Coupling of Methyl Iodide and Excess Boronic Acid Ester toward Fabrication of [11C]CH3-Incorporated PET Tracer.2013
- Author(s)
  Hiroko Koyama, Hisashi Doi, Masaaki Suzuki
- Journal Title
  
  Int. J. Org. Chem.
  
  Volume: 3 Issue: 03 Pages: 220-223
- DOI
  10.4236/ijoc.2013.33030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Pd0-Mediated Rapid Coupling of Methyl Iodide with Excess Amounts of Benzyl- and Cinnamylboronic Acid Esters: Efficient Method for Incorporation of Positron–Emitting 11C Radionuclide into Organic Frameworks by Coupling between Two sp3-Hybridized Carbons2013
- Author(s)
  Hiroko Koyama, Zhouen Zhang, Ryosuke Ijuin, Siqin, Jeongwan Son, Yuma Hatta, Masashi Ohta, Masahiro Wakao, Takamitsu Hosoya, Hisashi Doi, Masaaki Suzuki
- Journal Title
  
  RSC Advances
  
  Volume: 3 Issue: 24 Pages: 9391-9401
- DOI
  10.1039/c3ra40815a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation2010
- Author(s)
  Motomura, K., Ogura, M., Natsume, A., Yokoyama, H., and Wakabayashi, T
- Journal Title
  
  Neurosci Lett
  
  Volume: 485 Pages: 65-70
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation2010
- Author(s)
  Motomura K, Ogura M, Natsume A, Yokoyama H, Wakabayashi T
- Journal Title
  
  Neuroscience Letters
  
  Volume: 485(1) Pages: 65-70
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling2009
- Author(s)
  Yuki K, Natsume A, Yokoyama H, Kondo Y, Ohno M, Kato T, Chansakul P, Ito M, Kim SU, Wakabayashi T.
- Journal Title
  
  Cancer Lett 284
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling2009
- Author(s)
  Yuki, K., Natsume, A., Yokoyama, H., Kondo, Y., Ohno, M., Kato, T., Chansakul, P., Ito, M., Kim, S. U., and Wakabayashi, T
- Journal Title
  
  Cancer Lett
  
  Volume: 284 Pages: 71-79
- Data Source
  KAKENHI-PROJECT-21390408
[Patent] 1.[11C]標識非環式レチノイド、中枢神経系活性化剤及びそれらの製造方法2020
- Inventor(s)
  鈴木　正昭、伊藤　健吾、木村　泰之、古山　浩子、他
- Industrial Property Rights Holder
  鈴木　正昭、伊藤　健吾、木村　泰之、古山　浩子、他
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] PET imaging of [11C]NCGG401 for colony stimulating factor 1 receptor2021
- Author(s)
  Ogata A, Yamada T, Abe J, Ichise M, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K, Kimura Y
- Organizer
  NRM 2021 MAPPING NEURORECEPTORS AT WORK
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] RIPK1を標的とした新規ＰＥＴリガンド開発の試みと有効性の評価2021
- Author(s)
  池沼　宏、古山浩子、小懸綾、季斌、山田貴史、永井裕司、阿部潤一郎、市瀬正則、加藤隆司、鈴木正昭、木村泰之
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] Development of a novel PET ligand for receptor-interacting protein kinase 1 in brain2021
- Author(s)
  Ikenuma H, Ogata A, Koyama H, Yamada T, Abe J, Ichise M, Kato T, Suzuki M, Ito K, Kimura Y
- Organizer
  NRM 2021 MAPPING NEURORECEPTORS AT WORK
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] In vitro脳内出血病理モデルに対するレチノイドの組織保護効果2021
- Author(s)
  中西咲乃，倉内祐樹，関貴弘，木村泰之，鈴木正昭，鈴木恵一，古山浩子，香月博志
- Organizer
  第141年会日本薬学会
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] Improved (R,S)-[11C]isoproterenol formulation toward clinical study2019
- Author(s)
  Hiroshi Ikenuma, Hiroko Koyama, Yasuyuki Kimura, Junichiro Abe, Yasuhiro Kawasumi, Aya Ogata, Takashi Yamada, Takashi Kato, Kengo Ito, Masaaki Suzuki
- Organizer
  The 59th Annual Scientific Meeting of the Japanese Society of Nuclear Medicine
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] PET imaging of colony stimulating factor 1 receptor in rat brains.2019
- Author(s)
  Ogata A, Kimura Y, Yamada T, Ichise M, Ikenuma H, Abe J, Koyama H, Suzuki M, Kato T, Ito K.
- Organizer
  Brain & Brain PET 2019,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] PET imaging of colony stimulating factor 1 receptor2019
- Author(s)
  Aya Ogata, Yasuyuki Kimura, Takashi Yamada, Masanori Ichise, Junichiro Abe, Hiroshi Ikenuma, Hiroko Koyama, Masaaki Suzuki, Takashi Kato, and Kengo Ito
- Organizer
  The 59th Annual Scientific Meeting of the Japanese Society of Nuclear Medicine
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] PET imaging of colony stimulating factor 1 receptor in rat brains2019
- Author(s)
  A. Ogata,Y. Kimura, T. Yamada, M. Ichise, H. Ikenuma, J, Abe, H. Koyama, M. Suzuki, T. Kato, K. Ito
- Organizer
  Brain & Brain PET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] Colony stimulating factor 1 receptorを標的としたミクログリア特異的PETイメージングの開発2019
- Author(s)
  小縣綾、木村泰之、山田貴史、市瀬正則、阿部潤一郎、池沼宏、古山浩子、鈴木正昭、加藤隆司、伊藤健吾
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] Formulation of 11C-labeled (R,S)-isoproterenol and pharmacokinetic studies in rats2019
- Author(s)
  Hiroshi Ikenuma, Aya Ogata, Yasuyuki Kimura, Hiroko Koyama, Junichiro Abe, Takashi Yamada, Masanori Ichise, Takashi Kato, Masaaki Suzuki, and Kengo Ito
- Organizer
  Brain & Brain PET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] Formulation of 11C-labeled (R,S)-isoproterenol and pharmacokinetic studies in rats.2019
- Author(s)
  Ikenuma H, Ogata A, Kimura Y, Koyama H, Abe J, Yamada T, Ichise M, Kato T, Suzuki M, Ito K
- Organizer
  Brain & Brain PET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Improved (R,S)-[11C]isoproterenol formulation toward clinical study2019
- Author(s)
  池沼宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣綾、山田貴史、加藤隆司、伊藤健吾、鈴木正昭
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 脳移行性グルコース・ギンゴライド連結体の設計とPETプローブ化2019
- Author(s)
  鈴木恵一，古山浩子，池沼宏，沢田知辰，石井里咲，石井英樹，土居久志，木村泰之，鈴木正昭
- Organizer
  第50回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-18K06575
[Presentation] Synthesis of 11C-Labeled (R,S)-Isoproterenol and Preclinical PET Study2018
- Author(s)
  Ikenuma H, Koyama H, Kajino N, Kimura Y, Ogata A, Abe J, Kawasumi Y, Kato T, Suzuki M, Ito K
- Organizer
  The World Molecular Imaging Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Development of PET imaging of Colony Stimulating Factor 1 Receptor Expressed on Microglia.2018
- Author(s)
  Ogata A, Kimura Y, Yamada T, Bin Ji, Seki C, Ichise M, Abe J, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K
- Organizer
  The XII International Symposium of Functional Neuroreceptor Mapping of the Living Brain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] The evaluation of a novel PET ligand for colony stimulating factor 1 receptor in status epilepticus model rat brains.2018
- Author(s)
  Ogata A, Kimura Y, Yamada T, Bin Ji, Seki C, Ichise M, Abe J, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K
- Organizer
  nnual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] Synthesis of highly-qualified 11C-labeled (R,S)-isoproterenol aimed at a clinical study2017
- Author(s)
  Ikenuma H, Koyama H, Kimura Y, Abe J, Kawasumi K, Ogata A, Kato T, Ito K, Suzuki M.
- Organizer
  The 12th Asia Oceania Congress of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 臨床研究を目的とした11C標識化(R,S)-イソプロテレノールの高効率合成法の開発2017
- Author(s)
  池沼　宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣　綾、加藤隆司、伊藤健吾、鈴木正昭
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 認知症治療薬としてのイソプロテレノールの小動物PETを用いたラット脳内移行性の検討2017
- Author(s)
  小縣　綾、木村泰之、池沼　宏、古山浩子、関千江、山田貴史、鈴木正昭、加藤隆司、伊藤健吾
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Brain penetration of isoproterenol as a drug of dementia measured in rats with a micro-PET2017
- Author(s)
  Ogata A, Kimura Y, Ikenuma H, Koyama H, Seki C, Yamada T, Suzuki M, Kato T, Ito K.
- Organizer
  The 12th Asia Oceania Congress of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Evaluation of TlOH Effects for Pd0-Mediated Cross-Coupling of Methyl Iodide and Excess Boronic Acid Esters toward 11C-Incorporated PET Tracer Synthesis, Research area (10) Bench to Bedside2015
- Author(s)
  Hiroko Koyama, Hisashi Doi, Masaaki Suzuki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] Evaluation of TlOH Effects for Pd0-Mediated Cross-Coupling of Methyl Iodide and Excess Boronic Acid Esters toward 11C-Incorporated PET Tracer Synthesis2015
- Author(s)
  Hiroko Koyama, Hisashi Doi, Masaaki Suzuki
- Organizer
  PACIFICHEM 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460147
[Presentation] Synthesis of Disease Oriented and Novel PET Probe by Revolutionarily 11C Labeling Method
- Author(s)
  Hiroko Koyama
- Organizer
  Japan-China Nuclear Medicine Joint Symposium in Okinawa
- Place of Presentation
  Mercure Hotel Okinawa, Naha
- Year and Date
  2015-03-14 – 2015-03-15
- Invited
- Data Source
  KAKENHI-PROJECT-25460147

1. SUZUKI Masaaki (90093046)

# of Collaborated Projects: 9 results

# of Collaborated Products: 25 results
2. Kimura Yasuyuki (20423171)

# of Collaborated Projects: 9 results

# of Collaborated Products: 24 results
3. 小縣綾 (10805857)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
4. NATSUME Atsushi (30362255)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
5. 加藤隆司 (60242864)

# of Collaborated Projects: 6 results

# of Collaborated Products: 18 results
6. 池沼宏 (10751159)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
7. 外山宏 (90247643)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
8. 境崇行 (40881925)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. WAKABAYASHI Toshihiko (50220835)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
10. ISHII Hideki (80425610)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
11. 今村真一 (40873203)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. 季斌 (80392223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
13. 安野史彦 (60373388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KONDO Yutaka (00419897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. TAKEUCHI Ichiro (40335146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YANAGAWA Hiroshi (40327672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. DOI Hisashi (00421818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. UMEMURA Kazuo (40232912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. IJUIN Ryosuke (40442925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Ito Kengo (70184653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
21. 関千江 (40443080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 山田貴史 (50531860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. 鈴木啓介 (70635408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
24. 鈴木弘美 (30340269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
25. 二橋尚志 (00426496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 横井克典 (30899737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 百田洋之 (60469971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 川内敬子 (40434138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 三好大輔 (50388758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 加藤彰 (50793056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 錦見昭彦 (70404019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 近藤恭光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koyama Hiroko 古山 浩子

KOYAMA Hiroko 古山 浩子

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Synthesis of functional PET probes targeting enzymes specifically expressed in gliomaPrincipal Investigator

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Synthesis of 11C-labeled acyclic retinoids with high brain permeabilityPrincipal Investigator

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Development of rapid C-methylation between two sp3-hybridized carbons for incorporation of short-lived positron-emitting 11C radionuclidePrincipal Investigator

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Koyama Hiroko 古山浩子

KOYAMA Hiroko 古山浩子