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Katsuno Masahisa  勝野 雅央

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KATSUNO Masahisa  勝野 雅央

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Researcher Number 50402566
Other IDs
Affiliation (Current) 2023: 名古屋大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2023: 名古屋大学, 医学系研究科, 教授
2018: 名古屋大学, 大学院医学系研究科, 教授
2015 – 2016: 名古屋大学, 医学(系)研究科(研究院), 教授
2015 – 2016: 名古屋大学, 大学院医学系研究科, 教授
2012 – 2014: 名古屋大学, 医学系研究科, 准教授 … More
2011 – 2014: 名古屋大学, 医学(系)研究科(研究院), 准教授
2013: 名古屋大学, 大学院医学系研究科, 准教授
2011: 名古屋大学, 医学系研究科, 特任准教授
2011: 名古屋大学, 高等研究院, 特任准教授
2010: Nagoya University, 大学院・医学系研究科, 特任准教授
2007 – 2010: 名古屋大学, 高等研究院, 特任講師
2008: 名古屋大学, 高等研究院, 高等研究院 Less
Review Section/Research Field
Principal Investigator
Neurology / Medium-sized Section 52:General internal medicine and related fields / Biological Sciences
Except Principal Investigator
Neurology / Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields / Basic Section 43020:Structural biochemistry-related / Basic Section 51030:Pathophysiologic neuroscience-related / Biological Sciences
Keywords
Principal Investigator
運動ニューロン / 運動ニューロン疾患 / 神経変性疾患 / 球脊髄性筋萎縮症 / 骨格筋 / 筋萎縮性側索硬化症 / 神経変性 / TDP-43 / シナプス / ミトコンドリア … More / 転写障害 / アンドロゲン受容体 / ポリグルタミン / 胎児 / 神経活動 / インスリン / エクソサイトーシス / DNAメチル化 / マイクロアレイ / サイクリン依存性キナーゼ / 細胞周期 / TGF-beta / ポリグルタミン病 / シングルセル解析 / マルチモーダル解析 / オリゴデンドロサイト / コホート / トランスオミックス / α-シヌクレイン / カルシウムイメージング / シヌクレイン / 視覚野 / 嗅球 / 神経回路 / パーキンソン病 / レビー小体病型認知症 / RNAseq / アンチセンス核酸 / 運動 / 早期病態 / ライフステージ / 神経分化 / 後根神経節 / エクソソーム / DREADD / エクソサイト-シス / カルシウムチャンネル / Src / 糖尿病 / 呼吸機能 / バイオマーカー / シスタチンC / クレアチン / シグナル / リン酸化 / プロテオーム / シグナル伝達 / 神経科学 / 脳神経疾患 / Aktシグナル / NFkB / エピジェネティクス / 神経筋接合部 / セロトニン受容体 / 神経ペプチド / naratriptan / CGRP1 / JNK / CGRP-1 / 筋萎縮性側索硬化 / TGF-β / サーキット変性 / レンチウイルスベクター / heat shock factor-1 / 熱ショック蛋白質 / 酸化ストレス / Smad2 / NF-Y / 分子シャペロン / HSP70 / HSF-1 / TGF-βシグナル … More
Except Principal Investigator
球脊髄性筋萎縮症 / ALS / 筋萎縮性側索硬化症 / バイオマーカー / 神経変性疾患 / 運動ニューロン / 運動ニューロン疾患 / ポリグルタミン / 多系統萎縮症 / 核酸 / 脳神経疾患 / 神経変性 / 分子シャペロン / ポリグルタミン病 / 認知症 / VCP / 次世代シークエンサー / 疾患修飾療法 / リアルワールドデータ / 脊髄性筋萎縮症 / 前頭側頭葉変性症 / TBK1 / TDP-43 / FTLD / 免疫介在性ニューロパチー / 自己抗体 / 慢性炎症性脱髄性多発神経炎（CIDP） / モデルマウス / 女性保因者 / RNA / アンチセンス核酸 / トランスレーショナルリサーチ / MRI / 孤発性ALS / dynactin-1 / オートファジー / 線虫 / dynactin1 / CAGリピート / アンドロゲン受容体 / 17-DMAG / プロテアソーム / ユビキチン / TGF-β / 転写障害 / titin / 保因者 / パーキンソン症候群 / prodromal / 複合的重症度評価指標 / 予後規定因子 / SLC5A7 / 遠位型遺伝性運動ニューロパチー / 軸索 / FUS / CRISPR/Cas9 / iPS細胞 / シナプス / タンパク質凝集体 / シヌクレイン / タンパク質凝集 / タンパク伝播 / TDP-43伝播 / オリゴデンデロサイト / ニューロン / 凝集タンパク伝播 / TDP-43伝搬 / 異常タンパク凝集 / 補体 / 抗好中球細胞質抗体 / 顕微鏡的多発血管炎 / 血管炎 / 非全身性血管炎性ニューロパチー / Biomarker / neurofascin-155（NF155） / NOD B7-2 knockout mice / ニューロフィラメント-L（NF-L） / 慢性炎症性脱髄性多発根神経炎（CIDP） / Neurofascin-155 / ターゲットリシークエンス / 網羅的遺伝子解析 / 遺伝子変異 / ATXN3 / ACSL5 / KIF5A / 個別解析 / 頭部MRI / タンパク質品質管理 / SBMA / FTLD疾患関連遺伝子 / ALS疾患関連遺伝子 / 高次機能障害 / 筋萎縮性側策硬化症 / FTD / 網羅的解析 / 高次脳機能障害 / RNA編集 / リードスルー / 先天性ミオパチー / リュープリロレリン酢酸塩 / long-term effect / 疾患修飾薬 / real-world data / リュープロレリン酢酸塩 / slope analysis / 医師主導治験 / トランスポーター / 骨格筋 / クレアチントランスポーター / 骨格筋クレアチン / 運動ニューロン変性 / 髄液 / 治療薬探索 / 予後関連因子 / 予後因子 / 家族性アミロイトポリニューロパチー / ニューロパチー / トランスサイレチン / アミロイドーシス / アミロイド / 家族性アミロイドポリニューロパチー / polysome解析 / 脳神経外科 / ノックアウトマウス / 非運動症状 / 中途覚醒 / 日中過眠 / REM睡眠行動障害 / 認知機能 / サーカディアンリズム / パーキンソン病 / 睡眠障害 / メラトニン / 傍ランビエ絞輪部 / 軸索ー髄鞘間相互作用 / 傍ランビエ絞輪 (paranode) / 軸索－髄鞘間相互作用 / TAG-1ノックアウトモデル / NOD B7-2ノックアウトモデル / 多施設共同研究 / 動物モデル / 軸索‐髄鞘間相互作用 / 免疫グロブリン / 軸索-髄鞘間相互作用 / 傍ランヴィエ絞輪部 / IgG4サブクラス自己抗体 / 前向きコホート / 慢性炎症性脱髄性多発根神経炎 / 病期診断 / 安静時脳機能MRI / voxel-based morphometry / fractional anisotropy / mean diffusivity / レジストリ / X連鎖劣性遺伝 / 複合的臨床評価スケール / 低分子化合物 / 薬剤スクリーニング / 分子標的治療 / 病態 / 変異アンドロゲン受容体 / 病態解明 / 発現制御 / 遺伝子 / 加齢 / 予後 / 拡散テンソル / 脳容積 / マウスモデル / 線虫モデル / calcitonin-related polypeptide(CGRP1) / calcitonin / calcitonin/calcitonin-related polypeptide(CGRP1) / セロトニン受容体アゴニスト / ユビチキン / )球脊髄性筋萎縮症 / ユビキチン-プロテアゾーム系 / JNK / 細胞周期 / ユビキチンープロテアソーム系 / トランスジェニックマウス / Hsp90阻害剤 / ユビキチン-プロテアソーム系 / ペオニ抽出物 / 遺伝子発現解析 / dynactinl / 疾患モデル / cyclin C / 熱ショック蛋白質 / ユビキチン・プロテアソーム / リュープロレリン / ユビキチンープロテアソーム / 神経分子病態学 / ユビキチン-プロテアソーム / GGA / 17-AAG / HSP / ニューロフィラメント / dnactin1 / モーター蛋白質 / 軸索輸送 / CHIP / 脊髄小脳失調症(SCA) / 球脊髄性筋萎縮症(SBMA) Less

  • Research Projects

    (48 results)

  • Research Products

    (607 results)

  • Co-Researchers

    (49 People)

  •  Elucidation of temporal alteration in motor neuron-oligodendrocyte interaction in motor neuron diseasesPrincipal Investigator

    • Principal Investigator
      勝野 雅央
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University

  •  Investigation of mechanistic links between tauopathies and TDP-43 proteinopathies

    • Principal Investigator
      陸 雄一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Aichi Medical University

  •  球脊髄性筋萎縮症における超早期バイオマーカーの開発

    • Principal Investigator
      山田 晋一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  Development of neuronal aggregates-targeted therapeutics

    • Principal Investigator
      佐橋 健太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  Study of synaptic pahtology caused by FUS in amyotrophic lateral sclerosis

    • Principal Investigator
      横井 聡
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  運動ニューロン疾患の初期軸索病態の解明

    • Principal Investigator
      佐橋 健太郎
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University

  •  遠位型遺伝性運動ニューロパチー７型の病態解明と病態抑止療法の開発

    • Principal Investigator
      井口 洋平
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University

  •  球脊髄性筋萎縮症レジストリデータを用いた病態進行に関わる因子の同定

    • Principal Investigator
      橋詰 淳
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  Wide-field Ca imaging and trans-omics for mouse model of Lewy body diseasePrincipal Investigator

    • Principal Investigator
      勝野 雅央
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University

  •  免疫介在性ニューロパチーの疾患活動性を反映する新規バイオマーカーの開発

    • Principal Investigator
      飯島 正博
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  非全身性血管炎性ニューロパチーの病態解明と新規治療法の開発

    • Principal Investigator
      小池 春樹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  超早期ライフステージに着目した神経変性疾患の時空間特異性の解明Principal Investigator

    • Principal Investigator
      勝野 雅央
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University

  •  孤発性ALSにおける凝集型TDP-43の生体内伝播メカニズムの解明

    • Principal Investigator
      井口 洋平
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  Understanding of defective developmental gene regulation responsible for motor neuron degeneration

    • Principal Investigator
      Kentaro Sahashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Nagoya University

  •  異常タンパク分解系を標的とした運動ニューロン疾患治療薬の開発

    • Principal Investigator
      藤内 玄規
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Aichi Medical University
      Nagoya University

  •  Elucidation of the progression of multiple system atrophy by head MRI

    • Principal Investigator
      Hara Kazuhiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  候補遺伝子アプローチによる筋萎縮性側索硬化症病態関連遺伝子の探索

    • Principal Investigator
      中村 亮一
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  球脊髄性筋萎縮症に対する骨格筋トランスポーターを標的とした治療法開発

    • Principal Investigator
      土方 靖浩
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  Long-term effect of leuprorelin acetate on the patients with spinal and bulbar muscular atrophy

    • Principal Investigator
      Hashizume Atsushi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Nagoya University

  •  Understanding of intrinsic readthrough mechanisms of nonsense mutations for its therapeutic applications

    • Principal Investigator
      Sahashi Kentaro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University

  •  Discovery of novel target and disease modifying therapy for ALS/FTLD using neuro-specific transcriptome analysis

    • Principal Investigator
      IGUCHI YOHEI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Deciphering the mechanism of neuropathy and development of novel therapies in familial amyloid polyneuropathy

    • Principal Investigator
      Koike Haruki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Therapeutic development based on factors affecting progression and prognosis of amyotrophic lateral sclerosis

    • Principal Investigator
      Atsuta Naoki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of defective neural communication in motor neuron diseasesPrincipal Investigator

    • Principal Investigator
      Katsuno Masahisa
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Analysis of genes affecting cognitive function in sporadic ALS

    • Principal Investigator
      Nakamura Ryoichi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  多系統萎縮症の正確な病期診断法の開発

    • Principal Investigator
      伊藤 瑞規
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of dysregulation of exocytosis in sporadic amyotrophic lateral sclerosisPrincipal Investigator

    • Principal Investigator
      KATSUNO Masahisa
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of the axonal degenerative mechanism focusing on the paranodal molecules in immune-mediated neuropathy

    • Principal Investigator
      Iijima Masahiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Development of biomarkers of sleep disturbance in Parkinson's disease using salivary melatonin

    • Principal Investigator
      NAKAMURA TOMOHIKO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Biomarker study in the early phase patients with spinal and bulbar muscular atrophy

    • Principal Investigator
      Hashizume Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Development of biomarker and therapy for amyotrophic lateral sclerosis targeting cystatin CPrincipal Investigator

    • Principal Investigator
      Katsuno Masahisa
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Therapy development for neuromuscular degeneration in motor neuron diseasesPrincipal Investigator

    • Principal Investigator
      KATSUNO Masahisa
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Dissection of the pathomechanisms of motor neuron disease using antisense therapeutics

    • Principal Investigator
      Sahashi Kentaro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  A drug screening system for ALS by automated, quantitative motility analysis of C. elegans ALS model

    • Principal Investigator
      Sobue Gen
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of the pathogenesis of creatine metabolism dysregulation in spinal and bulbar muscular atrophy (SBMA) and clinical trial of oral creatine for patients with SBMAPrincipal Investigator

    • Principal Investigator
      KASTUNO Masahisa
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of pathogenesis of sporadic ALS using motor neuron specific-dynactin-1 knockout mice

    • Principal Investigator
      KAWAI Kaori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  統合的脳MRIネットワーク解析によるALSの運動機能-前頭葉機能間関連性の解明

    • Principal Investigator
      千田 譲
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Therapeutic strategy of neurodegenerative disease using microRNA

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of activity-dependent synapse pathology and development of therapy for spinal and bulbar muscular atrophyPrincipal Investigator

    • Principal Investigator
      KATSUNO MASAHISA
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Development of therapy targeting dysregulation of cell cycle and JNK pathway in polyglutamine diseasesPrincipal Investigator

    • Principal Investigator
      KATSUNO MASAHISA
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of molecular pathogenesis in motor neurocircuit degeneration and development of therapy for motor neuron diseasesPrincipal Investigator

    • Principal Investigator
      KATSUNO Masahisa
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University

  •  Elucidation of pathogenesis and therapy development of sporadic ALS by disease model

    • Principal Investigator
      TANAKA Fumiaki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Yokohama City University
      Nagoya University

  •  Development of Molecular Targeted Disease Modifying Therapy for Polyglutamine Diseases

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Elucidation of cellular signaling defect and mechanism of cell-specific degeneration in polyglutamine diseasesPrincipal Investigator

    • Principal Investigator
      KATSUNO Masahisa
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Therapeutic strategy for polyglutamine-mediated motor neuron disease via molecular chaperone-ubiquitin proteasome system

    • Principal Investigator
      ADACHI Hiroaki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Pathogenesis-based therapy development for polyglutamine diseases

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Development of animal model for sporadic ALS

    • Principal Investigator
      TANAKA Fumiaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University

  •  Development of pathogenesis-based therapy for polyglutamine diseases

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] Pharma Medica2021
    • Author(s)
      井口洋平、勝野雅央
    • Total Pages
      6
    • Publisher
      メディカルビュー社
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Book] 脳神経疾患最新の治療2021-20232021
    • Author(s)
      佐橋健太郎, 勝野雅央
    • Total Pages
      380
    • Publisher
      南江堂
    • ISBN
      9784524227853
    • Data Source
      KAKENHI-PROJECT-19H03545

  • [Book] Clinical Neuroscience2021
    • Author(s)
      橋詰　淳、倉沢史門、勝野雅央
    • Total Pages
      5
    • Publisher
      中外出版社
    • Data Source
      KAKENHI-PROJECT-21K07458

  • [Book] In Diseases of DNA Repair.(Shamim I.Ahmad ed.)(Clinical features and Molecular Mechanisms of spinal and bulbar muscular atrophy (SBMA).), Austin, USA2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
    • Publisher
      Landes Bioscience
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Book] Clinical features and Molecular Mechanisms of spinal and bulbar muscular atrophy (SBMA).(Shamim I. Ahmad ed., In Diseases of DNA Repair.)2009
    • Author(s)
      Katsuno, M., Banno, H., Suzuki, K., Adachi, H., Tanaka, F., Sobue, G.
    • Publisher
      Landes Bioscience
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Book] Clinical features and Molecular Mechanisms of spinal and bulbar muscularatrophy (SBMA). In Diseases of DNA Repair. Shamim I.Ahmad ed.2009
    • Author(s)
      Katsuno, M., Banno, H., Suzuki, K., Adachi, H., Tanaka, F., Sobue, G.
    • Total Pages
      256
    • Publisher
      Landes Bioscience
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Nucleic Acid-Based Therapeutic Approach for Spinal and Bulbar Muscular Atrophy and Related Neurological Disorders2022
    • Author(s)
      Hirunagi T, Sahashi K, Meilleur KG, Katsuno M.
    • Journal Title

      Genes

      Volume: 13 Issue: 1 Pages: 109-109

    • DOI

      10.3390/genes13010109

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00527

  • [Journal Article] Role of complement components in vasculitic neuropathy associated with systemic lupus erythematosus and rheumatoid arthritis.2022
    • Author(s)
      Fukami Y, Koike H, Iijima M, Mouri N, Nishi R, Katsuno M.
    • Journal Title

      Muscle Nerve.

      Volume: - Issue: 2 Pages: 175-182

    • DOI

      10.1002/mus.27636

    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Journal Article] Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology2022
    • Author(s)
      Tsujikawa K,Hamanaka K, Riku Y, Hattori Y, Hara N, Iguchi Y,Miyata T, Sobue G, Matsumoto N, Sahashi K, Katsuno M, et al.
    • Journal Title

      Sci Adv

      Volume: - Issue: 21

    • DOI

      10.1126/sciadv.abm5029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00527

  • [Journal Article] In vivo visualization of eosinophil secretion in eosinophilic granulomatosis with polyangiitis: An ultrastructural study2022
    • Author(s)
      Koike Haruki、Nishi Ryoji、Furukawa Soma、Mouri Naohiro、Fukami Yuki、Iijima Masahiro、Katsuno Masahisa
    • Journal Title

      Allergol. Int.

      Volume: 71 Issue: 3 Pages: 373-382

    • DOI

      10.1016/j.alit.2022.02.009

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Journal Article] Early ultrastructural lesions of ANCA- versus complement-associated vasculitis2022
    • Author(s)
      Koike Haruki, Furukawa Souma, Mouri Naohiro, Fukami Yuki, Iijima Masahiro, Katsuno Masahisa
    • Journal Title

      Neuropathology

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Journal Article] The wide-ranging clinical and genetic features in Japanese families with valosin-containing protein proteinopathy2021
    • Author(s)
      Ando T, Nakamura R, Kuru S, Yokoi D, Atsuta N, Koike H, Suzuki M, Hara K, Iguchi Y, Harada Y, Yoshida Y, Hattori M, Murakami A, Noda S, Kimura S, Sone J, Nakamura T, Goto Y, Mano K, Okada H, Okuda S, Nishino I, Ogi T, Sobue G, Katsuno M
    • Journal Title

      Neurobiology of Aging

      Volume: 100 Pages: 120.e1-120.e6

    • DOI

      10.1016/j.neurobiolaging.2020.10.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-20H03589

  • [Journal Article] Individual voxel-based morphometry adjusting covariates in multiple system atrophy.2021
    • Author(s)
      Ebina J, Hara K, Watanabe H, Kawabata K, Yamashita F, Kawaguchi A, Yoshida Y, Kato T, Ogura A, Masuda M, Ohdake R, Mori D, Maesawa S, Katsuno M, Kano O, Sobue G.
    • Journal Title

      Parkinsonism Relat Disord.

      Volume: 90 Pages: 114-119

    • DOI

      10.1016/j.parkreldis.2021.07.025

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07960, KAKENHI-PROJECT-21K11788

  • [Journal Article] ANCA‐associated neuropathy in systemic sclerosis: A case report and review of literature2021
    • Author(s)
      Takenaka Kayo、Takeichi Takuya、Nishi Ryoji、Suzuki Masashi、Koike Haruki、Katsuno Masahisa、Ogawa‐Momohara Mariko、Muro Yoshinao、Akiyama Masashi
    • Journal Title

      Journal of Cutaneous Immunology and Allergy

      Volume: 4 Issue: 2 Pages: 34-36

    • DOI

      10.1002/cia2.12153

    • Open Access
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Journal Article] Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS.2021
    • Author(s)
      Hirunagi T, Sahashi K, Tachikawa K, Leu AI, Nguyen M, Mukthavaram R, Karmali PP, Chivukula P, Tohnai G, Iida M, Onodera K, Ohyama M, Okada Y, Okano H, Katsuno M.
    • Journal Title

      Mol Ther Nucleic Acids.

      Volume: 24 Pages: 1-10

    • DOI

      10.1016/j.omtn.2021.02.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00527, KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-21K07471, KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-21K20686

  • [Journal Article] Association of serum neurofilament light chain levels with clinicopathology of chronic inflammatory demyelinating polyneuropathy, including NF155 reactive patients2021
    • Author(s)
      Fukami Y, Iijima M, Koike H, Yamada S, Hashizume A, Katsuno M.
    • Journal Title

      J Neurol .

      Volume: - Issue: 10 Pages: 3835-3844

    • DOI

      10.1007/s00415-021-10537-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Journal Article] Exploring the factors underlying remyelination arrest by studying the post‐transcriptional regulatory mechanisms of cystatin F gene2021
    • Author(s)
      Li Jiayi、Durose Wilaiwan Wisessmith、Ito Junko、Kakita Akiyoshi、Iguchi Yohei、Katsuno Masahisa、Kunisawa Kazuo、Shimizu Takeshi、Ikenaka Kazuhiro
    • Journal Title

      Journal of Neurochemistry

      Volume: 157 Issue: 6 Pages: 2070-2090

    • DOI

      10.1111/jnc.15190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Journal Article] Clinicoradiological features in amyotrophic lateral sclerosis patients with olfactory dysfunction2021
    • Author(s)
      Masuda Michihito、Watanabe Hirohisa、Ogura Aya、Ohdake Reiko、Kato Toshiyasu、Kawabata Kazuya、Hara Kazuhiro、Nakamura Ryoichi、Atsuta Naoki、Epifanio Bagarinao、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

      Volume: 22 Issue: 3-4 Pages: 260-266

    • DOI

      10.1080/21678421.2020.1859544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Journal Article] Significance of Oligomeric and Fibrillar Species in Amyloidosis: Insights into Pathophysiology and Treatment2021
    • Author(s)
      Koike Haruki、Iguchi Yohei、Sahashi Kentaro、Katsuno Masahisa
    • Journal Title

      Molecules

      Volume: 26 Issue: 16 Pages: 5091-5091

    • DOI

      10.3390/molecules26165091

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Journal Article] Genetic and functional analysis of KIF5A variants in Japanese patients with sporadic amyotrophic lateral sclerosis2021
    • Author(s)
      Nakamura R, Tohnai G, Atsuta N, Nakatochi M, Hayashi N, Watanabe H, Yokoi D, Watanabe H, Katsuno M, Izumi Y, Taniguchi A, Kanai K, Morita M, Kano O, Kuwabara S, Oda M, Abe K, Aoki M, Aiba I, Okamoto K, Mizoguchi K, Hattori N, Nakashima K, Kaji R, Sobue G
    • Journal Title

      Neurobiology of Aging

      Volume: 97 Pages: 147.e11-147.e17

    • DOI

      10.1016/j.neurobiolaging.2020.07.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Journal Article] Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration2021
    • Author(s)
      Riku Yuichi、Seilhean Danielle、Duyckaerts Charles、Boluda Susana、Iguchi Yohei、Ishigaki Shinsuke、Iwasaki Yasushi、Yoshida Mari、Sobue Gen、Katsuno Masahisa
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 8 Pages: 3843-3843

    • DOI

      10.3390/ijms22083843

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16586, KAKENHI-PROJECT-20H03589

  • [Journal Article] Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells2021
    • Author(s)
      Kanda Mitsuro、Shimizu Dai、Nakamura Shunsuke、Sawaki Koichi、Umeda Shinichi、Miwa Takashi、Tanaka Haruyoshi、Inokawa Yoshikuni、Hattori Norifumi、Hayashi Masamichi、Tanaka Chie、Nakayama Goro、Iguchi Yohei、Katsuno Masahisa、Kodera Yasuhiro
    • Journal Title

      Oncogene

      Volume: 40 Issue: 36 Pages: 5495-5504

    • DOI

      10.1038/s41388-021-01945-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03589, KAKENHI-PROJECT-20H03750

  • [Journal Article] Nerve biopsy in acquired neuropathies2021
    • Author(s)
      Sommer Claudia、Carroll Antonia S、Koike Haruki、Katsuno Masahisa、Ort Nora、Sobue Gen、Vucic Steve、Spies Judith M、Doppler Kathrin、Kiernan Matthew C
    • Journal Title

      Journal of the Peripheral Nervous System

      Volume: 26 Issue: S2

    • DOI

      10.1111/jns.12464

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Journal Article] Aggresome formation and liquid?liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 432020
    • Author(s)
      Watanabe Seiji、Inami Hidekazu、Oiwa Kotaro、Murata Yuri、Sakai Shohei、Komine Okiru、Sobue Akira、Iguchi Yohei、Katsuno Masahisa、Yamanaka Koji
    • Journal Title

      Cell Death & Disease

      Volume: 11 Issue: 10 Pages: 909-909

    • DOI

      10.1038/s41419-020-03116-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-19KK0214, KAKENHI-PROJECT-20H03589, KAKENHI-PROJECT-18H02740, KAKENHI-PROJECT-17H04986

  • [Journal Article] Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs2020
    • Author(s)
      Onodera K, Shimojo D, Ishihara Y, Yano M, Miya F, Banno H, Kuzumaki N, Ito T, Okada R, Ohyama M, Yoshida M, Tsunoda T, Katsuno M, Doyu M, Sobue G, Okano H, Okada Y
    • Journal Title

      Mol. Brain

      Volume: 13 Issue: 1 Pages: 18-18

    • DOI

      10.1186/s13041-020-0561-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-19H03576, KAKENHI-PROJECT-18K15470, KAKENHI-PROJECT-20K16587, KAKENHI-PROJECT-20K16611, KAKENHI-PROJECT-19J40240

  • [Journal Article] Association between IL-5 levels and the Clinicopathological Features of Eosinophilic Granulomatosis with Polyangiitis2020
    • Author(s)
      Nishi Ryoji、Koike Haruki、Ohyama Ken、Fukami Yuki、Iijima Masahiro、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Neurology

      Volume: 96 Issue: 5 Pages: 226-229

    • DOI

      10.1212/wnl.0000000000011142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Journal Article] NUS1 mutation in a family with epilepsy, cerebellar ataxia, and tremor2020
    • Author(s)
      Araki Kunihiko、Nakamura Ryoichi、Ito Daisuke、Kato Kohji、Iguchi Yohei、Sahashi Kentaro、Toyama Miho、Hamada Kensuke、Okamoto Nobuhiko、Wada Yoshinao、Nakamura Tomohiko、Ogi Tomoo、Katsuno Masahisa
    • Journal Title

      Epilepsy Research

      Volume: 164 Pages: 106371-106371

    • DOI

      10.1016/j.eplepsyres.2020.106371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Journal Article] Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis.2020
    • Author(s)
      Ikenaka K, Ishigaki S, Iguchi Y, Kawai K, Fujioka Y, Yokoi S, Abdelhamid RF, Nagano S, Mochizuki H, Katsuno M, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 79 Issue: 4 Pages: 370-377

    • DOI

      10.1093/jnen/nlaa003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09690, KAKENHI-PROJECT-17K09753, KAKENHI-PROJECT-18K07367, KAKENHI-PROJECT-20H03589

  • [Journal Article] The neural network basis of altered decision‐making in patients with amyotrophic lateral sclerosis2020
    • Author(s)
      Imai Kazunori、Masuda Michihito、Watanabe Hirohisa、Ogura Aya、Ohdake Reiko、Tanaka Yasuhiro、Kato Toshiyasu、Kawabata Kazuya、Riku Yuichi、Hara Kazuhiro、Nakamura Ryoichi、Atsuta Naoki、Bagarinao Epifanio、Katahira Kentaro、Ohira Hideki、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 7 Issue: 11 Pages: 2115-2126

    • DOI

      10.1002/acn3.51185

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KT0002, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-19KK0062, KAKENHI-PROJECT-19H01201

  • [Journal Article] Prognosis of amyotrophic lateral sclerosis patients undergoing tracheostomy invasive ventilation therapy in Japan2020
    • Author(s)
      Hayashi Naoki、Atsuta Naoki、Yokoi Daichi、Nakamura Ryoichi、Nakatochi Masahiro、Katsuno Masahisa、Izumi Yuishin、Kanai Kazuaki、Hattori Nobutaka、Taniguchi Akira、Morita Mitsuya、Kano Osamu、Shibuya Kazumoto、Kuwabara Satoshi、Suzuki Naoki、Aoki Masashi、Aiba Ikuko、Mizoguchi Kouichi、Oda Masaya、Kaji Ryuji、Sobue Gen
    • Journal Title

      Journal of Neurology, Neurosurgery & Psychiatry

      Volume: 91 Issue: 3 Pages: 285-290

    • DOI

      10.1136/jnnp-2019-322213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-17K16110

  • [Journal Article] Therapeutic monoclonal antibody targeting of neuronal pentraxin receptor to control metastasis in gastric cancer2020
    • Author(s)
      Kanda Mitsuro、Shimizu Dai、Sawaki Koichi、Nakamura Shunsuke、Umeda Shinichi、Miwa Takashi、Tanaka Haruyoshi、Tanaka Chie、Hayashi Masamichi、Iguchi Yohei、Yamada Suguru、Katsuno Masahisa、Kodera Yasuhiro
    • Journal Title

      Molecular Cancer

      Volume: 19 Issue: 1 Pages: 131-131

    • DOI

      10.1186/s12943-020-01251-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Journal Article] A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis.2020
    • Author(s)
      Nakamura R, Misawa K, Tohnai G, Nakatochi M, Furuhashi S, Atsuta N, Hayashi N, Yokoi D, Watanabe H, Watanabe H, Katsuno M, Izumi Y, Kanai K, Hattori N, Morita M, Taniguchi A, Kano O, Oda M, Shibuya K, Kuwabara S, Suzuki N, Aoki M, Ohta Y, Yamashita T, Abe K, Hashimoto R, Aiba I, Okada Y, Nagasaki M, Sobue G. et al.,
    • Journal Title

      Commun Biol.

      Volume: 23 Issue: 1 Pages: 526-526

    • DOI

      10.1038/s42003-020-01251-2

    • NAID

      120007178464

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-20K07754, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-19H03576, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-18K07519

  • [Journal Article] A nerve conduction study predicts the prognosis of sporadic amyotrophic lateral sclerosis2020
    • Author(s)
      Imai Eriko、Nakamura Tomohiko、Atsuta Naoki、Nakatochi Masahiro、Suzuki Masashi、Harada Yumiko、Nakamura Ryoichi、Hayashi Naoki、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Journal of Neurology

      Volume: 267 Issue: 9 Pages: 2524-2532

    • DOI

      10.1007/s00415-020-09858-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Journal Article] Differential clinicopathologic features of EGPA-associated neuropathy with and without ANCA2020
    • Author(s)
      Nishi Ryoji、Koike Haruki、Ohyama Ken、Fukami Yuki、Ikeda Shohei、Kawagashira Yuichi、Iijima Masahiro、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Neurology

      Volume: 94 Issue: 16 Pages: e1726-e1737

    • DOI

      10.1212/wnl.0000000000009309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Journal Article] Long-term Effects of Androgen Deprivation in a Patient with Spinal and Bulbar Muscular Atrophy - A Case Report with 14 Years of Follow-up2019
    • Author(s)
      Hijikata Yasuhiro、Hashizume Atsushi、Yamada Shinichiro、Ito Daisuke、Banno Haruhiko、Suzuki Keisuke、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Intern. Med.

      Volume: 58 Issue: 15 Pages: 2231-2234

    • DOI

      10.2169/internalmedicine.1592-18

    • NAID

      130007686841

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2019-08-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07523

  • [Journal Article] Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy2019
    • Author(s)
      Iida Madoka、Sahashi Kentaro、Kondo Naohide、Nakatsuji Hideaki、Tohnai Genki、Tsutsumi Yutaka、Noda Seiya、Murakami Ayuka、Onodera Kazunari、Okada Yohei、Nakatochi Masahiro、Tsukagoshi Okabe Yuka、Shimizu Shinobu、Mizuno Masaaki、Adachi Hiroaki、Okano Hideyuki、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 4262-4262

    • DOI

      10.1038/s41467-019-12282-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-18K16656, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-18K15361

  • [Journal Article] Evolution of amyloid fibrils in hereditary transthyretin amyloidosis: an ultrastructural study2019
    • Author(s)
      Koike Haruki、Nishi Ryoji、Ikeda Shohei、Kawagashira Yuichi、Iijima Masahiro、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Amyloid

      Volume: 26 Issue: sup1 Pages: 26-26

    • DOI

      10.1080/13506129.2019.1582496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] 増大特集 ALS2019 ALSにおける患者レジストリの役割-JaCALSなど2019
    • Author(s)
      熱田 直樹、中村 亮一、林 直毅、藤内 玄規、勝野 雅央、祖父江 元
    • Journal Title

      BRAIN and NERVE

      Volume: 71 Issue: 11 Pages: 1215-1225

    • DOI

      10.11477/mf.1416201431

    • ISSN
      1344-8129, 1881-6096
    • Year and Date
      2019-11-01
    • Data Source
      KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778

  • [Journal Article] Common clinicopathological features in late-onset hereditary transthyretin amyloidosis (Ala97Gly, Val94Gly and Val30Met)2019
    • Author(s)
      Koike Haruki、Nakamura Tomohiko、Nishi Ryoji、Ikeda Shohei、Kawagashira Yuichi、Iijima Masahiro、Yasuda Takeshi、Mukai Eiichiro、Date Yukari、Shiomi Kazutaka、Nakazato Masamitsu、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Amyloid

      Volume: 26 Issue: sup1 Pages: 24-25

    • DOI

      10.1080/13506129.2019.1582495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Multi-Ethnic Comparison of the Characteristics of Amyotrophic Lateral Sclerosis-Related TBK1 Gene Variants2019
    • Author(s)
      Tohnai Genki、Nakamura Ryoichi、Nakatochi Masahiro、Atsuta Naoki、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Journal of Neurology & Neuromedicine

      Volume: 4 Issue: 1 Pages: 7-11

    • DOI

      10.29245/2572.942x/2019/1.1236

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-17K16118

  • [Journal Article] Clinicopathological spectrum and recent advances in the treatment of hereditary transthyretin amyloidosis2019
    • Author(s)
      Koike Haruki、Fukami Yuki、Nishi Ryoji、Kawagashira Yuichi、Iijima Masahiro、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 7 Pages: 166-173

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Ultrastructure in transthyretin amyloidosis: from pathophysiology to therapeutic insights2019
    • Author(s)
      Koike H, Katsuno M.
    • Journal Title

      Biomedicines

      Volume: 7 Issue: 1 Pages: 11-11

    • DOI

      10.3390/biomedicines7010011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Cardiac and peripheral vasomotor autonomic functions in hereditary transthyretin amyloidosis with non-Val30Met mutation.2019
    • Author(s)
      Koike H, Nakamura T, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      Amyloid

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Cardiovascular autonomic functions in late-onset hereditary transthyretin amyloidosis with Val30Met mutation.2019
    • Author(s)
      Nakamura T, Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      Amyloid

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Disease Affects Bdnf Expression in Synaptic and Extrasynaptic Regions of Skeletal Muscle of Three SBMA Mouse Models2019
    • Author(s)
      Halievski K, Nath SR, Katsuno M, Adachi H, Sobue G, Breedlove SM, Lieberman AP, Jordan CL.
    • Journal Title

      Int J Mol Sci

      Volume: 20 Issue: 6 Pages: 1314-1314

    • DOI

      10.3390/ijms20061314

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-19K07970

  • [Journal Article] Semantic deficits in ALS related to right lingual/fusiform gyrus network involvement2019
    • Author(s)
      Ogura Aya、Watanabe Hirohisa、Kawabata Kazuya、Ohdake Reiko、Tanaka Yasuhiro、Masuda Michihito、Kato Toshiyasu、Imai Kazunori、Yokoi Takamasa、Hara Kazuhiro、Bagarinao Epifanio、Riku Yuichi、Nakamura Ryoichi、Kawai Yoshinari、Nakatochi Masahiro、Atsuta Naoki、Katsuno Masahisa、Sobue Gen
    • Journal Title

      EBioMedicine

      Volume: 47 Pages: 506-517

    • DOI

      10.1016/j.ebiom.2019.08.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778

  • [Journal Article] Elevated serum creatine kinase in the early stage of sporadic amyotrophic lateral sclerosis.2019
    • Author(s)
      Ito D, Hashizume A, Hijikata Y, Yamada S, Iguchi Y, Iida M, Kishimoto Y, Moriyoshi H, Hirakawa A, Katsuno M.
    • Journal Title

      J Neurol.

      Volume: 266 Issue: 12 Pages: 2952-2961

    • DOI

      10.1007/s00415-019-09507-6

    • NAID

      120006786260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-17K09753, KAKENHI-PROJECT-18K15361

  • [Journal Article] Common clinicopathological features in late-onset hereditary transthyretin amyloidosis (Ala97Gly, Val94Gly, and Val30Met).2019
    • Author(s)
      Koike H, Nakamura T, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Yasuda T, Mukai E, Date Y, Shiomi K, Nakazato M, Katsuno M, Sobue G.
    • Journal Title

      Amyloid

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Increase of arginine dimethylation correlates with the progression and prognosis of ALS.2019
    • Author(s)
      Ikenaka K, Atsuta N, Maeda Y, Hotta Y, Nakamura R, Kawai K, Yokoi D, Hirakawa A, Taniguchi A, Morita M, Mizoguchi K, Mochizuki H, Kimura K, Katsuno M, Sobue G.
    • Journal Title

      Neurology.

      Volume: 92 Issue: 16 Pages: e1868-e1877

    • DOI

      10.1212/wnl.0000000000007311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-19K07973

  • [Journal Article] Expanding the spectrum of transthyretin amyloidosis2019
    • Author(s)
      Koike Haruki、Katsuno Masahisa
    • Journal Title

      Muscle & Nerve

      Volume: 61 Issue: 1 Pages: 3-4

    • DOI

      10.1002/mus.26741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes52019
    • Author(s)
      Kondo N, Tohnai G, Sahashi K, Iida M, Kataoka M, Nakatsuji H, Tsutsumi Y, Hashizume A, Adachi H, Koike H, Shinjo K, Kondo Y, Sobue G, Katsuno M.
    • Journal Title

      EMBO Mol Med

      Volume: none Issue: 5

    • DOI

      10.15252/emmm.201708547

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-18K15361

  • [Journal Article] Nasometric Scores in spinal and bulbar muscular atrophy - Effects of palatal lift prosthesis on dysarthria and dysphagia2019
    • Author(s)
      Tanaka Seiya、Hashizume Atsushi、Hijikata Yasuhiro、Yamada Shinichiro、Ito Daisuke、Nakayama Atsushi、Kurita Kenichi、Yogo Hiroaki、Banno Haruhiko、Suzuki Keisuke、Yamamoto Masahiko、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 407 Pages: 116503-116503

    • DOI

      10.1016/j.jns.2019.116503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07523

  • [Journal Article] Long-term Effects of Androgen Deprivation in a Patient with Spinal and Bulbar Muscular Atrophy - A Case Report with 14 Years of Follow-up2019
    • Author(s)
      Hijikata Yasuhiro、Hashizume Atsushi、Yamada Shinichiro、Ito Daisuke、Banno Haruhiko、Suzuki Keisuke、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Intern Med

      Volume: 58 Pages: 2231-2234

    • NAID

      130007686841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07523

  • [Journal Article] Cardiac and peripheral vasomotor autonomic functions in hereditary transthyretin amyloidosis with non-Val30Met mutation2019
    • Author(s)
      Koike Haruki、Nakamura Tomohiko、Nishi Ryoji、Ikeda Shohei、Kawagashira Yuichi、Iijima Masahiro、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Amyloid

      Volume: 26 Issue: sup1 Pages: 13-14

    • DOI

      10.1080/13506129.2019.1582023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Evolution of amyloid fibrils in hereditary transthyretin amyloidosis: an ultrastructural study.2019
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      Amyloid

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets2019
    • Author(s)
      Araki Kunihiko、(他10名）、Ishigaki Shinsuke、Nakamichi Yoko、Tsunekawa Shin、Seino Yusuke、Yamamoto Akiko、Takayama Yasunori、Hidaka Shihomi、Tominaga Makoto、Ohara-Imaizumi Mica、Suzuki Atsushi、Ishiguro Hiroshi、Enomoto Atsushi、Yoshida Mari、Arima Hiroshi、Muramatsu Shin-ichi、Sobue Gen、Katsuno Masahisa
    • Journal Title

      Journal of Clinical Investigation

      Volume: 129 Issue: 9 Pages: 3578-3593

    • DOI

      10.1172/jci124481

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-WRAPUP-19H05447, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17K08547, KAKENHI-PROJECT-17K09753

  • [Journal Article] Cardiovascular autonomic functions in late-onset hereditary transthyretin amyloidosis with Val30Met mutation2019
    • Author(s)
      Nakamura Tomohiko、Koike Haruki、Nishi Ryoji、Ikeda Shohei、Kawagashira Yuichi、Iijima Masahiro、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Amyloid

      Volume: 26 Issue: sup1 Pages: 6-6

    • DOI

      10.1080/13506129.2019.1582018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Efficacy and safety of leuprorelin acetate for subjects with spinal and bulbar muscular atrophy: pooled analyses of two randomized-controlled trials2019
    • Author(s)
      Hashizume Atsushi、JASMITT study group、Katsuno Masahisa、Suzuki Keisuke、Banno Haruhiko、Takeuchi Yu、Kawashima Motoshi、Suga Noriaki、Mano Tomoo、Araki Amane、Hijikata Yasuhiro、Hirakawa Akihiro、Sobue Gen
    • Journal Title

      Journal of Neurology

      Volume: 266 Issue: 5 Pages: 1211-1221

    • DOI

      10.1007/s00415-019-09251-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07523, KAKENHI-PROJECT-17K17843

  • [Journal Article] Distinct manifestation of cognitive deficits associate with different resting-state network disruptions in non-demented patients with Parkinson's disease.2018
    • Author(s)
      Kawabata K
    • Journal Title

      J Neurol.

      Volume: 265(3) Issue: 3 Pages: 688-700

    • DOI

      10.1007/s00415-018-8755-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16117, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-16K09713

  • [Journal Article] Biomarker-based analysis of preclinical progression in spinal and bulbar muscular atrophy.2018
    • Author(s)
      Hijikata Y, Hashizume A, Yamada S, Inagaki T, Ito D, Hirakawa A, Suzuki K, Atsuta N, Tsuboi T, Hattori M, Hori A, Banno H, Sobue G, Katsuno M.
    • Journal Title

      Neurology

      Volume: 90 Issue: 17 Pages: 1501-1509

    • DOI

      10.1212/wnl.0000000000005360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K09311

  • [Journal Article] The morphology of amyloid fibrils and their impact on tissue damage in hereditary transthyretin amyloidosis: An ultrastructural study.2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Sakurai T, Shimohata T, Katsuno M, Sobue G.
    • Journal Title

      J Neurol Sci

      Volume: 394 Pages: 99-106

    • DOI

      10.1016/j.jns.2018.09.011

    • NAID

      120006554498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Preclinical progression of neurodegenerative diseases.2018
    • Author(s)
      Katsuno M, Sahashi K, Iguchi Y, Hashizume A
    • Journal Title

      Nagoya J Med Sci

      Volume: 80 Pages: 289-298

    • NAID

      120006502462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Journal Article] Ultrastructural mechanisms of macrophage-induced demyelination in CIDP.2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      Neurology. 2018 Dec 4;91(23):1051-1060.

      Volume: 91 Issue: 23 Pages: 1051-1060

    • DOI

      10.1212/wnl.0000000000006625

    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Journal Article] Clinical and Imaging Features of Multiple System Atrophy: Challenges for an Early and Clinically Definitive Diagnosis.2018
    • Author(s)
      H Watanabe, Y. Riku, K Hara, K Kawabata, T Nakamura, M Ito, M Hirayama, M Yoshida, M Katsuno, G Sobue.
    • Journal Title

      J Mov Disord

      Volume: 11 (No3) Issue: 3 Pages: 107-120

    • DOI

      10.14802/jmd.18020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-16K09713, KAKENHI-PROJECT-17K16117

  • [Journal Article] Restoration of a Conduction Block after the Long-term Treatment of CIDP with Anti-neurofascin 155 Antibodies: Follow-up of a Case over 23 Years2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Atsuta N, Nakamura T, Hirayama M, Ogata H, Yamasaki R, Kira JI, Katsuno M, Sobue G.
    • Journal Title

      Intern. Med.

      Volume: 57 Issue: 14 Pages: 2061-2066

    • DOI

      10.2169/internalmedicine.0455-17

    • NAID

      130007404902

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2018-07-15
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Journal Article] Corpus callosal involvement is correlated with cognitive impairment in multiple system atrophy.2018
    • Author(s)
      Hara K, Watanabe H, Bagarinao E, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Tsuboi T, Ito M, Atsuta N, Niwa H, Taoka T, Maesawa S, Naganawa S, Katsuno M, Sobue G.
    • Journal Title

      J Neurol.

      Volume: 265 Issue: 9 Pages: 2079-2087

    • DOI

      10.1007/s00415-018-8923-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K10397, KAKENHI-PROJECT-18K19510, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-17K16117

  • [Journal Article] Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis2018
    • Author(s)
      Tohnai Genki、Nakamura Ryoichi、Sone Jun、Nakatochi Masahiro、Yokoi Daichi、Katsuno Masahisa、Watanabe Hazuki、Watanabe Hirohisa、Ito Mizuki、Li Yuanzhe、Izumi Yuishin、et al. Atsuta Naoki、Sobue Gen
    • Journal Title

      Neurobiology of Aging

      Volume: 64 Pages: 158.e15-158.e19

    • DOI

      10.1016/j.neurobiolaging.2017.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-17K16118, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-17J03762

  • [Journal Article] Age-related impairment in Addenbrooke's cognitive examination revised scores in patients with amyotrophic lateral sclerosis.2018
    • Author(s)
      Masuda M, Watanabe H, Tanaka Y, Ohdake R, Ogura A, Yokoi T, Imai K, Kawabata K, Riku Y, Hara K, Nakamura R, Atsuta N, Katsuno M, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler Frontotemporal Degener.

      Volume: Epub ahead of print Issue: 7-8 Pages: 1-7

    • DOI

      10.1080/21678421.2018.1510009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-17K16117

  • [Journal Article] Widespread Cardiac and Vasomotor Autonomic Dysfunction in Non-Val30Met Hereditary Transthyretin Amyloidosis2018
    • Author(s)
      Koike H, Nakamura T, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      Intern. Med.

      Volume: 57 Issue: 23 Pages: 3365-3370

    • DOI

      10.2169/internalmedicine.1113-18

    • NAID

      130007539665

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2018-12-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] IGF-1 for spinal and bulbar muscular atrophy: hope and challenges.2018
    • Author(s)
      Hashizume A, Katsuno M.
    • Journal Title

      Lancet Neurol.

      Volume: 17 Issue: 12 Pages: 1026-1027

    • DOI

      10.1016/s1474-4422(18)30359-4

    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Journal Article] Pre-clinical symptoms of SBMA may not be androgen-dependent: Implications from two SBMA mouse models.2018
    • Author(s)
      Xu Y, Halievski K, Katsuno M, Adachi H, Sobue G, Breedlove M, Jordan CL.
    • Journal Title

      Hum Mol Genet in press

      Volume: 未 Issue: 14 Pages: 2425-2442

    • DOI

      10.1093/hmg/ddy142

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195

  • [Journal Article] Systemic angiopathy and axonopathy in hereditary transthyretin amyloidosis with Ala97Gly (p. Ala117Gly) mutation: a post-mortem analysis.2018
    • Author(s)
      Koike H, Yasuda T, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Sobue G, Katsuno M.
    • Journal Title

      Amyloid

      Volume: 25 Issue: 2 Pages: 141-142

    • DOI

      10.1080/13506129.2018.1474734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] 早期・進行期パーキンソン病の症状2018
    • Author(s)
      中村 友彦, 勝野 雅央
    • Journal Title

      日本臨床

      Volume: 53 Pages: 232-237

    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Journal Article] Severe hyposmia and aberrant functional connectivity in cognitively normal Parkinson's disease.2018
    • Author(s)
      Yoneyama N
    • Journal Title

      PLoS One.

      Volume: 13(1) Issue: 1 Pages: e0190072-e0190072

    • DOI

      10.1371/journal.pone.0190072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16117, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-16K09713

  • [Journal Article] Quantitative Assessment of Swallowing Dysfunction in Patients with Spinal and Bulbar Muscular Atrophy2017
    • Author(s)
      Hashizume Atsushi、Banno Haruhiko、Katsuno Masahisa、Hijikata Yasuhiro、Yamada Shinichiro、Inagaki Tomonori、Suzuki Keisuke、Sobue Gen
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 23 Pages: 3159-3165

    • DOI

      10.2169/internalmedicine.8799-16

    • NAID

      130006235519

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09311

  • [Journal Article] Long-term treatment with leuprorelin for spinal and bulbar muscular atrophy: natural history-controlled study2017
    • Author(s)
      Hashizume Atsushi、Katsuno Masahisa、Suzuki Keisuke、Hirakawa Akihiro、Hijikata Yasuhiro、Yamada Shinichiro、Inagaki Tomonori、Banno Haruhiko、Sobue Gen
    • Journal Title

      Journal of Neurology, Neurosurgery & Psychiatry

      Volume: 88 Issue: 12 Pages: 1026-1032

    • DOI

      10.1136/jnnp-2017-316015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09311

  • [Journal Article] Transforming growth factor-β signaling is upregulated in sporadic inclusion body myositis.2017
    • Author(s)
      Noda S, Koike H, Maeshima S, Nakanishi H, Iijima M, Matsuo K, Kimura S, Katsuno M, Sobue G.
    • Journal Title

      Muscle Nerve.

      Volume: 55 Issue: 5 Pages: 741-747

    • DOI

      10.1002/mus.25405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Journal Article] Altered tau isoform ratio caused by loss of Fus and Sfpq function leads to FTLD-like phenotypes2017
    • Author(s)
      Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno H, Sobue G.
    • Journal Title

      Cell Reports

      Volume: 18 Issue: 5 Pages: 1118-1131

    • DOI

      10.1016/j.celrep.2017.01.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01568, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117007, KAKENHI-PROJECT-26290016, KAKENHI-PROJECT-16K15480, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K14569, KAKENHI-PROJECT-17K09753, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-15H04278, KAKENHI-PLANNED-26117004, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K06793, KAKENHI-PROJECT-15K09310

  • [Journal Article] Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2017
    • Author(s)
      Riku Y., Watanabe H., Yoshida M., Mimuro M., Iwasaki Y., Masuda M., Ishigaki S., Katsuno M., Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: in press Issue: 8 Pages: 801-811

    • DOI

      10.1093/jnen/nlw053

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-15K19483, KAKENHI-PROJECT-15K09310, KAKENHI-ORGANIZER-26117001

  • [Journal Article] 球脊髄性筋萎縮症の早期診断2017
    • Author(s)
      土方靖浩　橋詰　淳　勝野雅央　祖父江元
    • Journal Title

      神経内科

      Volume: 86 Pages: 17-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09311

  • [Journal Article] Cardiac and peripheral vasomotor autonomic functions in late-onset transthyretin Val30Met familial amyloid polyneuropathy.2017
    • Author(s)
      Koike H, Nakamura T, Hashizume A, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G
    • Journal Title

      J Neurol

      Volume: 264 Issue: 11 Pages: 2293-2302

    • DOI

      10.1007/s00415-017-8629-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Journal Article] Correlation of insulin resistance and motor function in spinal and bulbar muscular atrophy.2017
    • Author(s)
      Nakatsuji H, Araki A, Hashizume A, Hijikata Y, Yamada S, Inagaki T, Suzuki K, Banno H, Suga N, Okada Y, Ohyama M, Nakagawa T, Kishida K, Funahashi T, Shimomura I, Okano H, Katsuno M, Sobue G.
    • Journal Title

      J Neurol.

      Volume: in press Issue: 5 Pages: 839-847

    • DOI

      10.1007/s00415-017-8405-3

    • NAID

      120006331845

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-17K19465, KAKENHI-PUBLICLY-17H05707, KAKENHI-PROJECT-15H04278

  • [Journal Article] Structural MRI correlates of amyotrophic lateral sclerosis progression2017
    • Author(s)
      Senda Joe、Atsuta Naoki、Watanabe Hirohisa、Bagarinao Epifanio、Imai Kazunori、Yokoi Daichi、Riku Yuichi、Masuda Michihito、Nakamura Ryoichi、Watanabe Hazuki、Ito Mizuki、Katsuno Masahisa、Naganawa Shinji、Sobue Gen
    • Journal Title

      Journal of Neurology, Neurosurgery & Psychiatry

      Volume: 88 Issue: 11 Pages: 901-907

    • DOI

      10.1136/jnnp-2016-314337

    • NAID

      120006375888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002

  • [Journal Article] Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin-155 and anti-contactin-1 antibodies.2017
    • Author(s)
      Koike H, Kadoya M, Kaida KI, Ikeda S, Kawagashira Y, Iijima M, Kato D, Ogata H, Yamasaki R, Matsukawa N, Kira JI, Katsuno M, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: epub ahead of print Issue: 6 Pages: 465-473

    • DOI

      10.1136/jnnp-2016-314895

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09693, KAKENHI-PROJECT-16H07051

  • [Journal Article] Alcoholic Myelopathy and Nutritional Deficiency2017
    • Author(s)
      Koike H, Nakamura T, Ikeda S, Takahashi M, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 1 Pages: 105-108

    • DOI

      10.2169/internalmedicine.56.7364

    • NAID

      130005239492

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Journal Article] 【神経疾患のゲノム医療】 筋萎縮性側索硬化症のゲノム医療2017
    • Author(s)
      中村 亮一, 藤内 玄規, 熱田 直樹, 勝野 雅央, 祖父江 元
    • Journal Title

      神経内科

      Volume: 86 Pages: 678-685

    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Journal Article] 3'UTR Length-Dependent Control of SynGAP Isoform α2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function.2017
    • Author(s)
      Yokoi S, Udagawa T, Fujioka Y, Honda D, Okado H, Watanabe H, Katsuno M.
    • Journal Title

      Cell Rep

      Volume: 20(13) Issue: 13 Pages: 3071-3084

    • DOI

      10.1016/j.celrep.2017.08.100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K09310

  • [Journal Article] Disruption of blood-nerve barriers in hereditary transthyretin (ATTR) amyloidosis.2017
    • Author(s)
      Koike H, Ikeda S, Takahashi M, Kawagashira Y, Iijima M, Misumi Y, Ando Y, Ikeda SI, Katsuno M, Sobue G
    • Journal Title

      Amyloid

      Volume: 24(suppl) Issue: sup1 Pages: 89-90

    • DOI

      10.1080/13506129.2017.1278691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09777, KAKENHI-PROJECT-15H04841

  • [Journal Article] Intraepidermal nerve fibre density in POEMS (Crow-Fukase) syndrome and the correlation with sural nerve pathology.2016
    • Author(s)
      Ohyama K, Koike H, Hashimoto R, Takahashi M, Kawagashira Y, Iijima M, Katsuno M, Sobue G.
    • Journal Title

      J Neurol Sci.

      Volume: 365 Pages: 207-211

    • DOI

      10.1016/j.jns.2016.04.023

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461292, KAKENHI-PROJECT-16K09693

  • [Journal Article] Exosome secretion is a key pathway for clearance of pathological TDP-43.2016
    • Author(s)
      Iguchi Y,, Eid L,, Parent M,, Soucy G,, Bareil C,, Riku Y,, Kawai K,, Takagi S,, Yoshida M,, Katsuno M,, Sobue G., Julien JP.
    • Journal Title

      Brain

      Volume: 139 Issue: 12 Pages: 3187-3201

    • DOI

      10.1093/brain/aww237

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-16K15480, KAKENHI-ORGANIZER-26117001

  • [Journal Article] Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy.2016
    • Author(s)
      Hijikata Y., Katsuno M., Suzuki K., Hashizume A., Araki A., Yamada S., Inagaki T., Iida M., Noda S., Nakanishi H., Banno H., Mano T., Hirakawa A., Adachi H., Watanabe H., Yamamoto M., Sobue G.
    • Journal Title

      Ann Clin Transl Neurol

      Volume: 3 Issue: 7 Pages: 537-546

    • DOI

      10.1002/acn3.324

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-15K15338, KAKENHI-ORGANIZER-26117001

  • [Journal Article] Decreased Peak Expiratory Flow Associated with Muscle Fiber-Type Switching in Spinal and Bulbar Muscular Atrophy.2016
    • Author(s)
      Yamada S, Hashizume A, Hijikata Y, Inagaki T, Suzuki K, Kondo N, Kawai K, Noda S, Nakanishi H, Banno H, Hirakawa A, Koike H, Halievski K, Jordan CL, Katsuno M, Sobue G.
    • Journal Title

      PLoS One.

      Volume: 11(12) Issue: 12 Pages: e0168846-e0168846

    • DOI

      10.1371/journal.pone.0168846

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-16K15480

  • [Journal Article] Gene Expression Profile of Inflammatory Myopathy with Malignancy is Similar to that of Dermatomyositis rather than Polymyositis2016
    • Author(s)
      Noda, T., Iijima, M., Noda, S., Maeshima, S., Nakanishi, H., Kimura, S., Koike, H., Ishigaki, S., Iguchi, Y., Katsuno, M., and Sobue, G.
    • Journal Title

      Intern. Med.

      Volume: 55 Issue: 18 Pages: 2571-2580

    • DOI

      10.2169/internalmedicine.55.6706

    • NAID

      130005414859

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-16K09693, KAKENHI-ORGANIZER-26117001

  • [Journal Article] FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.2016
    • Author(s)
      Kino Y, Washizu C, Kurosawa M, Yamada M, Doi H, Takumi T, Adachi H, Katsuno M, Sobue G, Hicks GG, Hattori N, Shimogori T, Nukina N.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 35236-35236

    • DOI

      10.1038/srep35236

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01567, KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16H06316, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-25461299, KAKENHI-PROJECT-16K09683

  • [Journal Article] Schwann cell and endothelial cell damage in transthyretin familial amyloid polyneuropathy.2016
    • Author(s)
      Koike H, Ikeda S, Takahashi M, Kawagashira Y, Iijima M, Misumi Y, Ando Y, Ikeda SI, Katsuno M, Sobue G.
    • Journal Title

      Neurology.

      Volume: 87 Pages: 2220-2229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Journal Article] A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN.2016
    • Author(s)
      Watanabe H, Atsuta N, Hirakawa A, Nakamura R, Nakatochi M, Ishigaki S, Iida A, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: in press Issue: 8 Pages: 851-8

    • DOI

      10.1136/jnnp-2015-311541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-26461319, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-26670439, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-15K19485

  • [Journal Article] Next-generation sequencing of 28 ALS-related genes in a Japanese ALS cohort2016
    • Author(s)
      Ryoichi Nakamura, Jun Sone, Naoki Atsuta, Genki Tohnai, Hazuki Watanabe, Daichi Yokoi, Masahiro Nakatochi, Hirohisa Watanabe, Mizuki Ito, Jo Senda, Masahisa Katsuno, Fumiaki Tanaka, Yuanzhe Li, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Osamu Kano, Masaya Oda, Satoshi Kuwabara, Koji Abe.
    • Journal Title

      Neurobiology of Aging

      Volume: 39 Pages: 219-219

    • DOI

      10.1016/j.neurobiolaging.2015.11.030

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19485, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26670445, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25293207, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-26461319

  • [Journal Article] FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization.2015
    • Author(s)
      Udagawa, T., Fujioka, Y., Tanaka, M., Honda, D., Yokoi, S., Riku, Y., Ibi, D., Nagai, T., Yamada, K., Watanabe, H., Katsuno, M., Inada, T., Ohno, K., Sokabe, M., Okado, H., Ishigaki S*., and Sobue, G.
    • Journal Title

      Nat Commun

      Volume: 6 Issue: 1 Pages: 7098-7098

    • DOI

      10.1038/ncomms8098

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09310, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-26116003, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-24247028, KAKENHI-PROJECT-15H06719, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-25860708, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001

  • [Journal Article] A functional scale for spinal and bulbar muscular atrophy: Cross-sectional and longitudinal study.2015
    • Author(s)
      Hashizume A, Katsuno M, Suzuki K, Banno H, Suga N, Mano T, Araki A, Hijikata Y, Grunseich C, Kokkinis A, Hirakawa A, Watanabe H, Yamamoto M, Fischbeck KH, Sobue G
    • Journal Title

      Neuromuscul Disord.

      Volume: 25 Issue: 7 Pages: 554-562

    • DOI

      10.1016/j.nmd.2015.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439

  • [Journal Article] Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy.2015
    • Author(s)
      Sahashi K, Katsuno M, Hung G, Adachi H, Kondo N, Nakatsuji H, Tohnai G, Iida M, Bennett CF, Sobue G.
    • Journal Title

      Hum Mol Genet.

      Volume: 24(21) Issue: 21 Pages: 5985-94

    • DOI

      10.1093/hmg/ddv300

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461268, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26860665, KAKENHI-PROJECT-26293206

  • [Journal Article] Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells.2015
    • Author(s)
      Endo F, Komine O, Fujimori-Tonou N, Katsuno M, Jin S, Watanabe S, Sobue G, Dezawa M, Wyss-Coray T, Yamanaka K
    • Journal Title

      Cell Reports

      Volume: 11 Issue: 4 Pages: 592-604

    • DOI

      10.1016/j.celrep.2015.03.053

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860252, KAKENHI-PROJECT-26830046, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293208, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001

  • [Journal Article] Glycoprotein nonmetastatic melanoma protein B ameliorates skeletal muscle lesions in a SOD1G93A mouse model of amyotrophic lateral sclerosis.2015
    • Author(s)
      Nagahara Y, Shimazawa M, Tanaka H, Ono Y, Noda Y, Ohuchi K, Tsuruma K, Katsuno M, Sobue G, Hara H.
    • Journal Title

      J Neurosci Res.

      Volume: 93 Issue: 10 Pages: 1552-1566

    • DOI

      10.1002/jnr.23619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15337

  • [Journal Article] Myotonia-like symptoms in a patient with spinal and bulbar muscular atrophy.2015
    • Author(s)
      Araki K, Nakanishi H, Nakamura T, Atsuta N, Yamada S, Hijikata Y, Hashizume A, Suzuki K, Katsuno M, Sobue G
    • Journal Title

      Neuromuscul Disord.

      Volume: 25 Issue: 11 Pages: 913-915

    • DOI

      10.1016/j.nmd.2015.08.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439

  • [Journal Article] Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration.2015
    • Author(s)
      Ding Y, Adachi H, Katsuno M, Huang Z, Jiang YM, Kondo N, Iida M, Tohnai G, Nakatsuji H, Funakoshi H, Nakamura T, Sobue G
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 468 Issue: 4 Pages: 677-683

    • DOI

      10.1016/j.bbrc.2015.11.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26860665

  • [Journal Article] Head Lift Exercise Improves Swallowing Dysfunction in Spinal and Bulbar Muscular Atrophy2015
    • Author(s)
      Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Hijikata Y, Tanaka S, Takatsu J, Watanabe H, Yamamoto M, Sobue G
    • Journal Title

      Eur Neurol

      Volume: 74 Issue: 5-6 Pages: 251-258

    • DOI

      10.1159/000431088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439, KAKENHI-ORGANIZER-26117001

  • [Journal Article] Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.2015
    • Author(s)
      Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Ikenaka K, Watanabe H, Yamamoto M, Kishida K, Sobue G
    • Journal Title

      Hum Mol Genet.

      Volume: 24 Issue: 2 Pages: 314-329

    • DOI

      10.1093/hmg/ddu445

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26670440, KAKENHI-PROJECT-26860665, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002

  • [Journal Article] Factors affecting longitudinal functional decline and survival in amyotrophic lateral sclerosis patients.2014
    • Author(s)
      Watanabe H, Atsuta N, Nakamura R, Hirakawa A, Watanabe H, Ito M, Senda J, Katsuno M, Izumi Y, Morita M, Tomiyama H, Taniguchi A, Aiba I, Abe K, Mizoguchi K, Oda M, Kano O, Okamoto K, Kuwabara S, Hasegawa K, Imai T, Aoki M, Tsuji S, Nakano I, Kaji R, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler Frontotemporal Degener.

      Volume: Epub ahead of print Issue: 3-4 Pages: 230-6

    • DOI

      10.3109/21678421.2014.990036

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-26670439, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001

  • [Journal Article] Brugada syndrome in spinal and bulbar muscular atrophy.2014
    • Author(s)
      Araki A, Katsuno M, Suzuki K, Banno H, Suga N, Hashizume A, Mano T, Hijikata Y, Nakatsuji H, Watanabe H, Yamamoto M, Makiyama T, Ohno S, Fukuyama M, Morimoto S, Horie M, Sobue G
    • Journal Title

      Neurology

      Volume: 82 Issue: 20 Pages: 1813-1821

    • DOI

      10.1212/wnl.0000000000000434

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24659428, KAKENHI-PROJECT-25461054, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440, KAKENHI-PLANNED-26117002

  • [Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014
    • Author(s)
      Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
    • Journal Title

      Endocrinology.

      Volume: 155 Issue: 7 Pages: 2624-2634

    • DOI

      10.1210/en.2013-1756

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440

  • [Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014
    • Author(s)
      Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
    • Journal Title

      Endocrinology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014
    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
    • Journal Title

      Hum Mol Genet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Journal Article] Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy2014
    • Author(s)
      Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP
    • Journal Title

      Hum Mol Genet

      Volume: (Epub ahead of print) Issue: 5 Pages: 1376-1386

    • DOI

      10.1093/hmg/ddt527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428

  • [Journal Article] Potential therapeutic targets in polyglutamine-mediated diseases.2014
    • Author(s)
      Katsuno M, Watanabe H, Yamamoto M, Sobue G
    • Journal Title

      Expert Rev Neurother.

      Volume: 14 Issue: 10 Pages: 1215-1228

    • DOI

      10.1586/14737175.2014.956727

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670440

  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy.2014
    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G.
    • Journal Title

      Hum Mol Genet.

      Volume: 23 Issue: 13 Pages: 3552-3565

    • DOI

      10.1093/hmg/ddu066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440, KAKENHI-PROJECT-26860665, KAKENHI-PLANNED-26117002

  • [Journal Article] Tongue pressure as a novel biomarker of spinal and bulbar muscular atrophy (SBMA)2014
    • Author(s)
      Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Watanabe H, Tanaka S, Yamamoto M, Sobue G
    • Journal Title

      Neurology

      Volume: 82 Issue: 3 Pages: 255-262

    • DOI

      10.1212/wnl.0000000000000041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428

  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014
    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
    • Journal Title

      Hum Mol Genet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Schwann cell involvement in the peripheral neuropathy of spinocerebellar ataxia type 3.2014
    • Author(s)
      Suga N, Katsuno M, Koike H, Banno H, Suzuki K, Hashizume A, Mano T, Iijima M, Kawagashira Y, Hirayama M, Nakamura T, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Neuropathol Appl Neurobiol.

      Volume: 40 Issue: 5 Pages: 628-639

    • DOI

      10.1111/nan.12055

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670445

  • [Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014
    • Author(s)
      Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
    • Journal Title

      Endocrinology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] 脳腱黄色腫症と認知症2014
    • Author(s)
      桝田　道人、勝野　雅央、渡辺　宏久、千田　譲、祖父江　元
    • Journal Title

      神経内科

      Volume: 80 Pages: 107-114

    • Data Source
      KAKENHI-PROJECT-25461312

  • [Journal Article] Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis.2014
    • Author(s)
      Riku Y, Watanabe H, Yoshida M, Tatsumi S, Mimuro M, Iwasaki Y, Katsuno M, Iguchi Y, Masuda M, Senda J, Ishigaki S, Udagawa T, Sobue G
    • Journal Title

      JAMA Neurol.

      Volume: 71 Issue: 2 Pages: 172-179

    • DOI

      10.1001/jamaneurol.2013.5489

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24659429, KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-26293206

  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014
    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G.
    • Journal Title

      Hum Mol Genet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Journal Article] Translational research on disease-modifying therapies for neurodegenerative diseases2013
    • Author(s)
      Katsuno M, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 1 Issue: 1 Pages: 3-10

    • DOI

      10.1002/ncn3.7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-24659428

  • [Journal Article] RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-43.2013
    • Author(s)
      Takagi S, Iguchi Y, Katsuno M, Ishigaki S, Ikenaka K, Fujioka Y, Honda D, Niwa J, Tanaka F, Watanabe H, Adachi H, Sobue G.
    • Journal Title

      PLoS One.

      Volume: 28 Issue: 6 Pages: e66966-e66966

    • DOI

      10.1371/journal.pone.0066966

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-25293207

  • [Journal Article] A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.2013
    • Author(s)
      Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H.
    • Journal Title

      Nat Commun.

      Volume: 4 Issue: 1 Pages: 1816-1816

    • DOI

      10.1038/ncomms2828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-ORGANIZER-22110001, KAKENHI-PLANNED-22110002, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23500401, KAKENHI-PROJECT-24500378, KAKENHI-PROJECT-24700374, KAKENHI-PROJECT-25640066

  • [Journal Article] Neck weakness is a potent prognostic factor in sporadic amyotrophic lateral sclerosis patients.2013
    • Author(s)
      Nakamura R, Atsuta N, Watanabe H, Hirakawa A, Watanabe H, Ito M, Senda J, Katsuno M, Tanaka F, Izumi Y, Morita M, Ogaki K, Taniguchi A, Aiba I, Mizoguchi K, Okamoto K, Hasegawa K, Aoki M, Kawata A, Abe K, Oda M, Konagaya M, Imai T, Nakagawa M, Tsuji S, Kaji R, Nakano I, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 84 Issue: 12 Pages: 1365-1371

    • DOI

      10.1136/jnnp-2013-306020

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24406030, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25461312

  • [Journal Article] Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration2013
    • Author(s)
      Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G
    • Journal Title

      Nat Commun

      Volume: 4 Issue: 1 Pages: 1405-1405

    • DOI

      10.1038/ncomms2417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428, KAKENHI-PLANNED-22110005

  • [Journal Article] dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration2013
    • Author(s)
      Ikenaka K, Kawai K, Katsuno M, Huang Z, Jiang YM, Iguchi Y, Kobayashi K, Kimata T, Waza M, Tanaka F, Mori I, Sobue G
    • Journal Title

      PLoS One

      Volume: 8

    • NAID

      120007001030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm.2013
    • Author(s)
      Tanaka S, Banno H, Katsuno M, Suzuki K, Suga N, Hashizume A, Mano T, Araki A, Watanabe H, Adachi H, Tatsumi H, Yamamoto M, Sobue G.
    • Journal Title

      J Neurol Sci.

      Volume: 337 Issue: 1-2 Pages: 193-200

    • DOI

      10.1016/j.jns.2013.12.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005

  • [Journal Article] dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration2013
    • Author(s)
      Ikenaka K
    • Journal Title

      PLoS One

      Volume: 8 Issue: 2 Pages: e54511-e54511

    • DOI

      10.1371/journal.pone.0054511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175, KAKENHI-PROJECT-24247001, KAKENHI-PROJECT-25293207, KAKENHI-PLANNED-22110005, KAKENHI-PLANNED-22123010

  • [Journal Article] p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model2013
    • Author(s)
      Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, IidaM,Tohnai G, Qiang Q, Tanaka F, Yanagawa T, WarabiE,Ishii T, Sobue G
    • Journal Title

      J Neurosci

      Volume: 33 Issue: 18 Pages: 7710-7727

    • DOI

      10.1523/jneurosci.3021-12.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-24659428, KAKENHI-PROJECT-25220103

  • [Journal Article] Cortical and subcortical brain atrophy in Parkinson's disease with visual hallucination2013
    • Author(s)
      Watanabe, H. Senda, J. Kato, S. Ito, M. Atsuta, N. Hara, K. Tsuboi, T. Katsuno, M. Nakamura, T. Hirayama, M. Adachi, H. Naganawa, S. Sobue, G.
    • Journal Title

      Mov Disord

      Volume: 28 Issue: 12 Pages: 1732-6

    • DOI

      10.1002/mds.25641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591293, KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-25461313

  • [Journal Article] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease2013
    • Author(s)
      Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G
    • Journal Title

      J Neurochem

      Volume: 126 Issue: 1 Pages: 122-130

    • DOI

      10.1111/jnc.12172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-24659428

  • [Journal Article] Loss of TDP-43 causes age-dependent progressive motor neuron degeneration2013
    • Author(s)
      Iguchi Y
    • Journal Title

      Brain

      Volume: 136 Issue: 5 Pages: 1371-1382

    • DOI

      10.1093/brain/awt029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22390175, KAKENHI-PROJECT-22590965, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23659452, KAKENHI-PROJECT-25293020, KAKENHI-PLANNED-22110005

  • [Journal Article] Amyotrophic lateral sclerosis: an update on recent genetic insights.2013
    • Author(s)
      Iguchi Y, Katsuno M, Ikenaka K, Ishigaki S, Sobue G.
    • Journal Title

      J Neurol.

      Volume: 260 Issue: 11 Pages: 2917-2927

    • DOI

      10.1007/s00415-013-7112-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Journal Article] Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials.2012
    • Author(s)
      Hama T, Hirayama M, Hara T, Nakamura T, Atsuta N, Banno H, Suzuki K, Katsuno M, Tanaka F, Sobue G.
    • Journal Title

      Muscle Nerve

      Volume: 45 Issue: 2 Pages: 169-174

    • DOI

      10.1002/mus.22291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-21600003, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24500458

  • [Journal Article] c-Abl inhibition delays motor neuron degeneration in the G93A mouse2012
    • Author(s)
      Katsumata R, Ishigaki S, Katsuno M, Kawai K, Sone J, Huang Z, Adachi H,Tanaka F, Urano F, Sobue G
    • Journal Title

      an animal model of amyotrophic lateral sclerosis

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
    • Author(s)
      Miyazaki Y, Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G
    • Journal Title

      Nat Med

      Volume: 18 Issue: 7 Pages: 1136-1141

    • DOI

      10.1038/nm.2791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-23590473, KAKENHI-PUBLICLY-23110515

  • [Journal Article] Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by expanded polyglutamine2012
    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
    • Journal Title

      Nat Med

      Volume: 18 Issue: 10 Pages: 1531-1538

    • DOI

      10.1038/nm.2932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-24249047

  • [Journal Article] Differential change of clinical outcome measures in spinal and bulbar muscular atrophy: comparison of natural history with placebo-treated group.2012
    • Author(s)
      Hashizume A, Katsuno M, Banno H, Suzuki K, Suga N, Tanaka F, Sobue G.
    • Journal Title

      J Neurol.

      Volume: 259 Issue: 4 Pages: 712-719

    • DOI

      10.1007/s00415-011-6251-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986

  • [Journal Article] Defective axonal transport in motor neuron diseases.2012
    • Author(s)
      Ikenaka K, Katsuno M, Kawai K, Ishigaki S, Tanaka F, Sobue G.
    • Journal Title

      Int J Mol Sci.

      Volume: 13 Issue: 1 Pages: 1225-1238

    • DOI

      10.3390/ijms13011225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230

  • [Journal Article] IGF-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy2012
    • Author(s)
      Rinaldi C, Bott L, Chen K, Harmison G, Katsuno M, Sobue G, Pennuto M, Fischbeck KH
    • Journal Title

      Mol Med

      Volume: 18 Issue: 9 Pages: 1261-1268

    • DOI

      10.2119/molmed.2012.00271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230

  • [Journal Article] Current status of treatment of spinal and bulbar muscular atrophy2012
    • Author(s)
      Tanaka F, Katsuno M, Banno H, Suzuki K, Adachi H, Sobue G
    • Journal Title

      Neural Plast

      Volume: 2012 Pages: 369284-369284

    • DOI

      10.1155/2012/369284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428

  • [Journal Article] Molecular pathophysiology and disease-Modifying therapies for spinal and bulbar muscular atrophy2012
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Arch Neurol

      Volume: 69 Issue: 4 Pages: 436-440

    • DOI

      10.1001/archneurol.2011.2308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428

  • [Journal Article] Cross-sectional and longitudinal analysis of an oxidative stress biomarker for spinal and bulbar muscular atrophy.2012
    • Author(s)
      Mano, T., Katsuno, M., Banno, H., Suzuki, K., Suga, N., Hashizume, A., Tanaka, F., Sobue, G.
    • Journal Title

      Muscle Nerve

      Volume: 46 Issue: 5 Pages: 692-697

    • DOI

      10.1002/mus.23413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986

  • [Journal Article] Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases2012
    • Author(s)
      Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 83 Issue: 3 Pages: 329-335

    • DOI

      10.1136/jnnp-2011-301307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428

  • [Journal Article] Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies.2012
    • Author(s)
      Iguchi Y,Katsuno M,Takagi S.Ishigaki S,Niwa JI,Hasegawa M,Tanaka F,Sobue G
    • Journal Title

      Neurobiol Dis

      Volume: 45 Issue: 3 Pages: 862-870

    • DOI

      10.1016/j.nbd.2011.12.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-22390175, KAKENHI-PUBLICLY-23110526, KAKENHI-PROJECT-23240050, KAKENHI-PROJECT-23659452

  • [Journal Article] TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals.2012
    • Author(s)
      Sahashi K, Hua Y, Ling KK, Hung G, Rigo F, Horev G, Katsuno M, Sobue G, Ko CP, Bennett CF, Krainer AR.
    • Journal Title

      Genes Dev.

      Volume: 26 Issue: 16 Pages: 1874-1884

    • DOI

      10.1101/gad.197418.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Loss of TDP-43 causes age-dependent progressive motor neuron degeneration2012
    • Author(s)
      Iguchi Y, Katsuno M, Niwa JI, Takagi S, Ishigaki S, Ikenaka K, Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Tanaka F, Sobue G
    • Journal Title

      Brain

      Volume: 136 Pages: 1371-1382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Disruption of axonal transport in motor neuron diseases2012
    • Author(s)
      Ikenaka K, Katsuno M, Kawai K, Ishigaki S, Tanaka F, Sobue G
    • Journal Title

      Int J Mol Sci

      Volume: 13 Pages: 1225-1238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Longitudinal changes of outcome measures in spinal and bulbar muscular atrophy.2012
    • Author(s)
      Hashizume, A., Katsuno, M., Banno, H., Suzuki, K., Suga, N., Mano, T., Atsuta, N., Oe, H., Watanabe, H., Tanaka, F., Sobue, G.
    • Journal Title

      Brain

      Volume: 35 Issue: 9 Pages: 2838-2848

    • DOI

      10.1093/brain/aws170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986

  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy (SBMA).2012
    • Author(s)
      Banno, H., Katsuno, M., Suzuki, K., Tanaka, F., Sobue, G.
    • Journal Title

      Cell Tissue Res

      Volume: 349 Issue: 1 Pages: 313-320

    • DOI

      10.1007/s00441-012-1377-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428

  • [Journal Article] Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA)2012
    • Author(s)
      Katsuno M, Tanaka F, Adachi H, Banno H, Suzuki K, Watanabe H, Sobue G
    • Journal Title

      Prog Neurobiol

      Volume: 99 Issue: 3 Pages: 246-256

    • DOI

      10.1016/j.pneurobio.2012.05.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428

  • [Journal Article] c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis2012
    • Author(s)
      Katsumata R
    • Journal Title

      PLoS One

      Volume: 7 Issue: 9 Pages: e46185-e46185

    • DOI

      10.1371/journal.pone.0046185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175, KAKENHI-PLANNED-22110005

  • [Journal Article] Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions.2012
    • Author(s)
      Ishigaki S, Masuda A, Fujioka Y, Iguchi Y, Katsuno M, Shibata A, Urano F, Sobue G, Ohno K
    • Journal Title

      Sci Rep

      Volume: 2 Issue: 1 Pages: 529-529

    • DOI

      10.1038/srep00529

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659452, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659429, KAKENHI-PLANNED-22110005

  • [Journal Article] Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43linked to TDP-43 proteinopathies2012
    • Author(s)
      Iguchi Y, Katsuno M, Takagi S, Ishigaki S, Niwa J, Hasegawa M, Tanaka F, Sobue G.
    • Journal Title

      Neurobiol Dis

      Volume: 45 Pages: 862-870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Disruption of axonal transport in motor neuron diseases2012
    • Author(s)
      Ikenaka K, Katsuno M, Kawai K, Ishigaki S, Tanaka F, Sobue G
    • Journal Title

      Int J Mol Sci

      Volume: 13 Pages: 1225-1238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Transforming growth factor-β signaling in motor neuron diseases.2011
    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Current Mol Med. 11

      Pages: 48-56

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance towards disease-modifying therapy.2011
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Sobue .
    • Journal Title

      Lancet Neurol. 10

      Pages: 113-115

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.2011
    • Author(s)
      Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.
    • Journal Title

      J Neurosci31

      Pages: 5225-5234

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice2011
    • Author(s)
      Yu Z, Wang AM, Adachi H, Katsuno M, Sobue G, Yue Z, Robins DM, Lieberman AP
    • Journal Title

      PLoS Genet

      Volume: 7 Issue: 10 Pages: e1002321-e1002321

    • DOI

      10.1371/journal.pgen.1002321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230

  • [Journal Article] Transforming growth factor-β signaling in motor neuron diseases.2011
    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Current Mol Med.

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Transforming growth factor-β signaling in motor neuron diseases2011
    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      Curr Mol Med

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Transforming Growth Factor-β Signaling in Motor Neuron Diseases.2011
    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Curr Mol Med 11

      Pages: 48-56

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Transforming growth factor-b signaling in motor neuron diseases2011
    • Author(s)
      Katsuno M, et al.
    • Journal Title

      Culr Mol Med

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2011
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Sobue G.
    • Journal Title

      Lancet Neurol.

      Volume: 10 Pages: 113-115

    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.2011
    • Author(s)
      Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.
    • Journal Title

      J Neurosci.

      Volume: 31 Issue: 14 Pages: 5225-5234

    • DOI

      10.1523/jneurosci.5478-10.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-22659011, KAKENHI-PUBLICLY-23113701, KAKENHI-PROJECT-23390017

  • [Journal Article] A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.2011
    • Author(s)
      Iida A
    • Journal Title

      Hum Mol Genet

      Volume: 20 Issue: 18 Pages: 3684-3692

    • DOI

      10.1093/hmg/ddr268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PLANNED-22116010, KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-22590923, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23500433

  • [Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
    • Journal Title

      Adv Exp Med Biol 685

      Pages: 64-74

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci.

      Volume: 30 Pages: 5702-5707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2010
    • Author(s)
      Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Neurosci Res

      Volume: 88 Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010
    • Author(s)
      Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Transforming growth factor-beta signaling in motor neuron diseases.2010
    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Current Mol Med.

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010
    • Author(s)
      Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.2010
    • Author(s)
      Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res 88

      Pages: 123-135

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci.

      Volume: 30 Pages: 5702-5707

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2010
    • Author(s)
      Sone J, Niwa JI, Kawai K, Ishigaki S, Yamada SI, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res. 88

      Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci. 30

      Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010
    • Author(s)
      Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 685 Pages: 64-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2010
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Sobue G.
    • Journal Title

      Lancet Neurol.

      Volume: 10 Pages: 113-115

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010
    • Author(s)
      Katsuno, M., Adachi, H., Minamiyama, M., Waza, M., Doi, H., Kondo, N., Mizoguchi, H., Nitta, A., Yamada, K., Banno, H., Suzuki, K., Tanaka, F., Sobue, G.
    • Journal Title

      J. Neurosci 30

      Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar Museular atrophy.2010
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 81

      Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.2010
    • Author(s)
      Sone, J., Niwa, J.I., Kawai, K., Ishigaki, S., Yamada, S.I., Adachi, H., Katsuno, M., Tanaka, F., Doyu, M., Sobue, G.
    • Journal Title

      J Neurosci Res.

      Volume: 88 Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 685 Pages: 64-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.2010
    • Author(s)
      Sone J, Niwa JI, Kawai K, Ishigaki S, Yamada SI, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res. 88

      Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      J Neurosci

      Volume: 30 Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 81

      Pages: 567-571

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy2010
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 81

      Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2010
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Sobue G.
    • Journal Title

      Lancet Neurol.

      Volume: 10 Pages: 113-115

    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci 30

      Pages: 5702-5712

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci. 30

      Pages: 5702-5712

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] icroarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010
    • Author(s)
      Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.M
    • Journal Title

      PLoS One 5

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G ; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.
    • Journal Title

      Lancet Neurol.

      Volume: 9 Pages: 875-884

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci. 30

      Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G
    • Journal Title

      Lancet Neurol. 9

      Pages: 875-884

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Transforming growth factor-beta signaling in motor neuron diseases.2010
    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Current Mol Med.

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G ; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study gtoup.
    • Journal Title

      Lancet Neurol.

      Volume: 9 Pages: 875-884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Clinicopathological features of acute autonomic and sensory neuropathy.2010
    • Author(s)
      Koike H, Atsuta N, Adachi H, Iijima M, Katsuno M, Yasuda T, Fukada Y, Yasui K, Nakashima K, Horiuchi M, Shiomi K, Fukui K, Takashima S, Morita Y, Kuniyoshi K, Hasegawa Y, Toribe Y, Kajiura M, Takeshita S, Mukai E, Sobue G.
    • Journal Title

      Brain 133(10)

      Pages: 2881-2896

    • NAID

      10025625514

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      J Neurosci

      Volume: 30 Issue: 16 Pages: 5702-5712

    • DOI

      10.1523/jneurosci.0388-10.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue Cr ; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.
    • Journal Title

      Lancet Neurol.

      Volume: 9 Pages: 875-884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy.2010
    • Author(s)
      Mo K, Razak Z, Rao Y, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS ONE 5

      Pages: 12922-12922

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy.2009
    • Author(s)
      Banno, H., Katsuno, M., Suzuki, K., Tanaka, F., Sobue, G.
    • Journal Title

      Int J Mol Sci.

      Volume: 10 Pages: 1000-1012

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009
    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis: A study with tractography and diffusion-tensor imaging2009
    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler. (in press)

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] The case for cholesterol2009
    • Author(s)
      Katsuno M, et al.
    • Journal Title

      Nature Med (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis : a study with tractography and diffusion-tensor imaging2009
    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler. 10

      Pages: 288-294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy.2009
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Tanaka F.Sobue G.
    • Journal Title

      Int J Mol Sci. 10

      Pages: 1000-1012

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Getting a handle on Huntington's disease, the case for cholesterol2009
    • Author(s)
      Katsuno, M., Adachi, H., Sobue, G.
    • Journal Title

      Nat. Med. 15

      Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009
    • Author(s)
      Banno, H., Katsuno, M., Suzuki, K., Takeuchi, Y., Kawashima, M., Suga, N., Takamori, M., Ito, M., Nakamura, T., Matsuo, K., Yamada, S., Oki, Y., Adachi, H., Minamiyama, M., Waza, M., Atsuta, N., Watanabe, H., Fujimoto, Y., Nakashima, T., Tanaka, F., Doyu, M., Sobue, G.
    • Journal Title

      Ann Neurol 65

      Pages: 140-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009
    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse2009
    • Author(s)
      Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G
    • Journal Title

      Hum. Mol. Genet 18

      Pages: 898-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol2009
    • Author(s)
      Katsuno M, Adachi H, Sobue G
    • Journal Title

      Nat. Med 15

      Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Ann Neurol. 65

      Pages: 140-150

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Walking capacity evaluated by the 6-minute walk test in spinal and bulbar muscular atrophy2009
    • Author(s)
      Takeuchi Y, Katsuno M, Banno H, Suzuki K, Kawashima M, Atsuta N, Ito M, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Muscle Nerve 38

      Pages: 964-971

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy.2009
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Ann Neurol. 65

      Pages: 140-150

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases.2009
    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis : A study with tractography and diffusion-tensor imaging2009
    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G
    • Journal Title

      Amyotroph. Lateral Scler (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse2009
    • Author(s)
      Tokui, K., Adachi, H., Waza, M., Katsuno, M., Minamiyama, M., Doi, H., Tanaka, K., Hamazaki, J., Murata, S., Tanaka, F., Sobue, G.
    • Journal Title

      Hum. Mol. Genet. 18

      Pages: 898-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pathogenesis-targeting therapeutics for spinal and bulbar muscular atrophy (SBMA).2009
    • Author(s)
      Suzuki, K., Katsuno, M., Banno, H., Sobue, G.
    • Journal Title

      Neuropathology

      Volume: 29 Pages: 509-516

    • NAID

      10028192075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy.2009
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Ann Neurol 65

      Pages: 140-150

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse.2009
    • Author(s)
      Tokui K*, Adachi H*, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
    • Journal Title

      Hum Mol Genet(* Evenly contributed to the study) 18

      Pages: 898-910

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol.2009
    • Author(s)
      Katsuno M, Adachi H, Sobue G.
    • Journal Title

      Nat Med. 15

      Pages: 253-254

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Heat shock proteins in neurodegenerative diseases : pathogenic roles and therapeutic implications.2009
    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009
    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy2009
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      Int. J. Mol. Sci (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol2009
    • Author(s)
      Katsuno M, et.al.
    • Journal Title

      Nat. Med 15

      Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol.2009
    • Author(s)
      Katsuno M, et al
    • Journal Title

      Nat. Med 15

      Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse.2009
    • Author(s)
      Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
    • Journal Title

      Hum Mol Genet. 18

      Pages: 898-910

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications.2009
    • Author(s)
      Adachi, H., Katsuno, M., Waza, M., Minamiyama, M., Tanaka, F., Sobue, G.
    • Journal Title

      Int J Hyperthermia

      Volume: 25 Pages: 647-654

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis : a study with tractography and diffusion-tensor imaging.2009
    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler. 10

      Pages: 288-294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009
    • Author(s)
      Palazzolo, I., Stack, C., Kong, L., Musaro, A., Adachi, H., Katsuno, M., Sobue, G., Taylor, J.P., Sumner, C.J., Fischbeck, K.H., Pennuto, M.
    • Journal Title

      Neuron

      Volume: 63 Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse2009
    • Author(s)
      Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
    • Journal Title

      Hum Mol Genet 18

      Pages: 898-910

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases2009
    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications.2009
    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases.2009
    • Author(s)
      Iguchi, Y., Katsuno, M., Niwa, J., Yamada, S., Sone, J., Waza, M., Adachi, H., Tanaka, F., Nagata, K., Arimura, N., Watanabe, T., Kaibuchi, K., Sobue, G.
    • Journal Title

      J Biol Chem.

      Volume: 284 Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spina I and bulbar muscular atrophy2009
    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications.2009
    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases.2009
    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy2009
    • Author(s)
      Palazzolo, I., Stack, C., Kong, L., Musaro, A., Adachi, H., Katsuno, M., Sobue, G., Taylor, J.P., Sumner, C.J., Fischbeck, K.H., Pennuto, M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] The case for cholesterol2009
    • Author(s)
      Katsuno M, Adachi H, Sobue G.
    • Journal Title

      .Nature Med. (in press)

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases2009
    • Author(s)
      Iguchi, Y., Katsuno, M., Niwa, J., Yamada, S., Sone, J., Waza, M., Adachi, H., Tanaka, F., Nagata, K., Arimura, N., Watanabe, T., Kaibuchi, K., Sobue, G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pathogenesis-targeting Therapeutics for Spinal and Bulbar Muscular Atrophy (SBMA)2009
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Sobue G
    • Journal Title

      Neuropathology (in press)

    • NAID

      10028192075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases.2009
    • Author(s)
      Iguchi Y, Katsuno M, Niwa JI, Yamada SI, Sone J, Waza M, Adachi H, Tanaka F, Nagata KI, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem 284

      Pages: 22059-22066

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol.2009
    • Author(s)
      Katsuno M, Adachi H, Sobue G.
    • Journal Title

      Nat Med 15

      Pages: 253-254

    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications2009
    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-21229011

  • [Journal Article] Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP.2009
    • Author(s)
      Iijima, M., Tomita, M., Morozumi, S., Kawagashira, Y., Nakamura, T., Koike, H., Katsuno, M., Hattori, N., Tanaka, F., Yamamoto, M., Sobue, G.
    • Journal Title

      Neurology

      Volume: 73 Pages: 1348-1352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009
    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Ann. Neurol 65

      Pages: 140-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      Brain 131

      Pages: 229-239

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Molecular Genetics and Biomarkers of Polyglutamine Diseases2008
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Current Mol. Med. 8

      Pages: 221-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Refractory Peripheral Neuropathy Study Group of Japan. Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population2008
    • Author(s)
      Iijima M, Koike H, Hattori N, Tamakoshi A, Katsuno M, Tanaka F, Yamamoto M, Arimura K, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 79

      Pages: 1040-1043

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Molecular genetics and biomarkers of polyglutamine diseases.2008
    • Author(s)
      Katsuno M, et al
    • Journal Title

      Curr Mol Med 8

      Pages: 221-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390243

  • [Journal Article] Cognitive impairment in spinocerebellar ataxia type 62008
    • Author(s)
      Suenaga M, Kawai Y, Watanabe H, Atsuta N, Ito M, Tanaka F, Katsuno M, Fukatsu H, Naganawa S, Sobue G
    • Journal Title

      J. Neurol .Neurosurg. Psychiatry 79

      Pages: 496-499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Molecular genetics and biomarkers of polyglutamine diseases2008
    • Author(s)
      Katsuno M, et al.
    • Journal Title

      Curr Mol Med 8

      Pages: 221-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Molecular Genetics and Biomarkers of Polyglutamine Diseases2008
    • Author(s)
      Katsuno M, et.al.
    • Journal Title

      Current Mol. Med 8

      Pages: 221-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Molecular genetics and biomarkers of polyglutamine diseases2008
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Tanaka F, Adachi H, Sobue G.
    • Journal Title

      Curr Mol Med. 8

      Pages: 221-234

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008
    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008
    • Author(s)
      Suzuki, K., Katsuno, M., Banno, H., Takeuchi, Y., Atsuta, N., Ito, M., Watanabe, H., Yamashita, F., Hori, N., Nakamura, T., Hirayama, M., Tanaka, F., Sobue, G.
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Molecular Genetics and Biomarkers of Polyglutamine Diseases.2008
    • Author(s)
      Katsuno M, et al
    • Journal Title

      Current Mol. Med. 8

      Pages: 221-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Walking capacity evaluated by the 6-minute walk test in spinal and bulbar muscular atrophy2008
    • Author(s)
      Takeuchi Y, Katsuno M, Banno H, Suzuki K, Kawashima M, Atsuta N, Ito M, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Muscle Nerve 38

      Pages: 946-971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Therapeutic strategies for spinal and bulbar musculara atrophy (SBMA)2007
    • Author(s)
      Katsuno M, Bannno H, Suzuki K, Takeuchi Y, Minamiyama M, Waza M, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Drugns of the Future 32

      Pages: 907-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, Acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to athologic markers in sporadic amyotrophic lateral sclerosis2007
    • Author(s)
      Jiang Y, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwia J, Doyu M, Yoshida M, Hashizume Y, Sobue G
    • Journal Title

      Neuropathol Exp Neurol 66

      Pages: 617-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD12007
    • Author(s)
      Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Biol Chem 282

      Pages: 28087-28095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Ataxic vs painful form of paraneoplastic neuropathy2007
    • Author(s)
      Oki Y, Koike H, Iijima M, Mori K, Hattori N, Katsuno M, Nakamura T, Hirayama M, Tanaka F, Shiraishi M, Yazaki S, Nokura K, Yamamoto H,Sobue G
    • Journal Title

      Neurology 69

      Pages: 564-572

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2007
    • Author(s)
      Adachi, H., Waza, M., Tokui, K., Katsuno, M., Minamiyama, M., Tanaka, F., Doyu, M., Sobue, G.
    • Journal Title

      J. Neurosci 27

      Pages: 5115-5126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model2007
    • Author(s)
      Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanak F, Doyu M, Sobue G
    • Journal Title

      J Neurosci 27

      Pages: 5115-5126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis2007
    • Author(s)
      Jiang YM, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizume Y, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol 66

      Pages: 617-627

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Nonmyelinating Schwann cell involvement with well-preserved unmyelinated axons in Charco-Matie-Tooth disease type 1A2007
    • Author(s)
      Koike H, Iijima M, Mori K, Yamamoto M, Hattori N, Katsuno M, Tanaka F, Watanabe H, Doyu M, Yoshikawa H, Sobue G
    • Journal Title

      J Neuropathol Exp Neurol 66

      Pages: 1027-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
    • Author(s)
      Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Neuropathol Appl Neurobiol 33

      Pages: 135-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD12007
    • Author(s)
      Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Biol Chem 282

      Pages: 28087-28095

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Intravenous immunoglobulin therapy markedly ameliorates muscle weakness and severe pain in proximal diabetic neuropathy2007
    • Author(s)
      Kawagashira Y, Watanabe H, Oki Y, Iijima M, Koike H, Hattori N, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry 78

      Pages: 899-901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Gene expressions specifically detected in motor neurons (dynactin l, early growth response 3, Acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to athologic markers in sporadic amyotrophic lateral sclerosis2007
    • Author(s)
      Jiang Y, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwia J, Doyu M, Yoshida M, Hashizume Y, Sobue G
    • Journal Title

      Neuropathol Exp Neurol 66

      Pages: 617-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
    • Author(s)
      Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Neuropathol Appl Neurobiol 33

      Pages: 135-151

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] Ataxic vs painful form of paraneoplastic neuropathy2007
    • Author(s)
      Oki Y, Koike H, Iijima M, Mori K, Hattori N, Katsuno M, Nakamura T, Hirayama M, Tanaka F, Shiraishi M, Yazaki S, Nokura K, Yamamoto H, Sobue G
    • Journal Title

      Neurology 69

      Pages: 564-572

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Recent progress in alcoholic and thiamine-deficiency neuropathy2007
    • Author(s)
      Koike H, Oki Y, Iijima M, katsuno M, Hattori N, Sobue G
    • Journal Title

      Current trend in Neurology 2

      Pages: 79-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Therapeutic strategies for spinal and bulbar muscular atrophy (SBMA)2007
    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Minamiyama M, Waza M, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Drug Future 32

      Pages: 907-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2007
    • Author(s)
      Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci 27

      Pages: 5115-5126

    • Data Source
      KAKENHI-PROJECT-19390238

  • [Journal Article] CHIP Overexpression Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model2007
    • Author(s)
      Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J. Neurosci 27

      Pages: 5115-5126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Recent progress in alcoholic and thiamine-deficiency neuropathy2007
    • Author(s)
      Koike H, Oki Y, Iijima M, katsuno M, Hattori N, Sobue G
    • Journal Title

      Current trend in Neurology 2

      Pages: 79-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
    • Author(s)
      Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Neuropathol. Appl. Neurobiol 33

      Pages: 135-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
    • Author(s)
      Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Neuropathol Appl Neurobiol 33

      Pages: 135-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD12007
    • Author(s)
      Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Biol Chem 282

      Pages: 28087-28095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Reduces Mutant Androgen Receptor protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model2007
    • Author(s)
      Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanak F, Doyu M, Sobue G
    • Journal Title

      J Neurosci 27

      Pages: 5115-5126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Nonmyelinating Schwann cell involvement with well-preserved unmyelinated axons in Charco-Matie-Tooth disease type 1A2007
    • Author(s)
      Koike H, Iijima M, Mori K, Yamamoto M, Hattori N, Katsuno M, Tanaka F, Watanabe H, Doyu M, Yoshikawa H, Sobue G
    • Journal Title

      J Neuropathol Exp Neurol 66

      Pages: 1027-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033

  • [Journal Article] Intravenous immunoglobulin therapy markedly ameliorates muscle weakness and severe pain in proximal diabetic neuropathy2007
    • Author(s)
      Kawagashira Y, Watanabe H, Oki Y, Iijima M, Koike H, Hattori N, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry 78

      Pages: 899-901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Therapeutic strategies for spinal and bulbar musculara atrophy (SBMA)2007
    • Author(s)
      Katsuno M, Bannno H, Suzuki K, Takeuchi Y, Minamiyama M, Waza M, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Drugns of the Future 32

      Pages: 907-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Modulation of Hsp90 function in neurodegenerative disorders : a molecular targeted therapy against disease-causing protein.2006
    • Author(s)
      Waza M, Adachi H, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Mol Med (in press)

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin : A pathogenic marker.2006
    • Author(s)
      Banno H, Adachi H, Katsuno M, Suzuki K, Atsuta N, Watanabe H, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Ann Neurol 59

      Pages: 520-526

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Alleviating neurodegeneration by an anticancer agent : an Hsp90 inhibitor (17-AAG)2006
    • Author(s)
      Waza M, Adachi H, Katsuno M, Minamiyama M, Tanaka F, Sobue G
    • Journal Title

      Ann N Y Acad Sci 1086

      Pages: 21-34

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Gene expression profiling toward understanding of ALS pathogenesis2006
    • Author(s)
      Tanaka F, Niwa J, Ishigaki S, Katsuno M, Waza M, Yamamoto M, Doyu M, Sobue G
    • Journal Title

      Ann N Y Acad Sci 1086

      Pages: 1-10

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration2006
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Tokui K, Banno H, Suzuki K, Onoda Y, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Neurosci 26

      Pages: 12106-12117

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin : A pathogenic marker2006
    • Author(s)
      Banno H, Adachi H, Katsuno M, Suzuki K, Atsuta N, Watanabe H, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Ann Neurol 59

      Pages: 520-526

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Modulation of Hsp90 function in neurodegenerative disorders : a molecular-targeted therapy against disease-causing protein2006
    • Author(s)
      Waza M, Adachi H, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Mol Med 84

      Pages: 635-646

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pathogenesis, animal models and therapeutics in spinal and bulbar muscular atrophy (SBMA).2006
    • Author(s)
      Katsuno M, Adachi H, Waza M, Banno H, Suzuki K, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Exp Neurol (in press)

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Natural history of spinal and bulbar muscular atrophy (SBMA) : A study of 223 Japanes patients2006
    • Author(s)
      Atsuta N, Watanabe H, Ito M, Banno H, Suzuki K, Katsuno M, Tanaka F, Tamakoshi A, Sobue G
    • Journal Title

      Brain 129

      Pages: 1446-1455

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pathogenesis, animal models and therapeutics in Spinal and bulbar muscular atrophy (SBMA)2006
    • Author(s)
      Katsuno M, Adachi H, Waza M, Banno H, Suzuki K, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Exp Neurol 200

      Pages: 8-18

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.2005
    • Author(s)
      Waza M, Adachi H, Katsuno M, Minamiyama M, Sang C, Tanaka F, Inukai A, Doyu M, Sobue G
    • Journal Title

      Nature Med 11

      Pages: 1088-1095

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Clinical and electrophysiologic correlates of IVIg responsiveness in CIDP.2005
    • Author(s)
      Iijima M, Yamamoto M, Hirayama M, Tanaka F, Katsuno M, Mori K, Koike H, Hattori N, Arimura K, Nakagawa M, Yoshikawa H, Hayasaka K, Onodera O, Baba M, Yasuda H, Saito T, Nakazato M, Nakashima K, Kira J, Kaji R, Oka N, Sobue G
    • Journal Title

      Neurology 64

      Pages: 1471-1475

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease2005
    • Author(s)
      Katsuno, M., Sang, C., Adachi, H., Minamiyama, M., Waza, M., Tanaka, F., Doyu, M., Sobue, G.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A. 102

      Pages: 16801-16806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration2005
    • Author(s)
      Waza, M., Adachi, H., Katsuno, M., Minamiyama, M., Sang, C., Tanaka, F., Inukai, A., Doyu, M., Sobue, G.
    • Journal Title

      Nat. Med. 11

      Pages: 1088-1095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Widespread nuclear and cytoplasmic mutant androgen receptor accumulation in spinal and bulbar muscular atrophy.2005
    • Author(s)
      Adachi H, Katsuno M, Minamiyama M, Waza M, Sang C, Nakagomi Y, Kobayashi Y, Tanaka F, Doyu M, Inukai A, Yoshida M, Hashizume Y, Sobue G
    • Journal Title

      Brain 128

      Pages: 659-670

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] The wide spectrum of clinical manifestations in Sjogren's syndrome-associated neuropathy.2005
    • Author(s)
      Mori K, Iijima M, Koike H, Hattori N, Tanaka F, Watanabe H, Katsuno M, Fujita A, Aiba I, Ogata A, Saito T, Asakura K, Yoshida M, Hirayama M, Sobue G
    • Journal Title

      Brain 128

      Pages: 2158-2534

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease.2005
    • Author(s)
      Katsuno M, Sang C, Adachi H, Minamiyama M, Waza M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Proc Natl Acad Sci USA 102

      Pages: 16801-16806

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Journal Article] Gene expression profile of motor neurons in sporadic amyotrophic lateral sclerosis.2005
    • Author(s)
      Jiang YM, Yamamoto M, Kobayashi Y, Yoshihara T, Liang Y, Terao S, Takeuchi H, Ishigaki S, Katsuno M, Adachi H, Niwa J, Tanaka F, Doyu M, Yoshida M, Hashizume Y, Sobue G
    • Journal Title

      Ann Neurol 57

      Pages: 236-251

    • Data Source
      KAKENHI-PROJECT-17025020

  • [Patent] 抗神経変性疾患剤2012
    • Inventor(s)
      祖父江　元・勝野　雅央
    • Industrial Property Rights Holder
      祖父江　元・勝野　雅央
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-09-03
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Patent] 球脊髄性筋萎縮症治療薬2009
    • Inventor(s)
      祖父江元、勝野雅央、南山誠
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2009-277101
    • Filing Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Patent] 球脊髄性筋萎縮症治療薬2009
    • Inventor(s)
      祖父江元・南山誠・勝野雅央
    • Industrial Property Number
      2009-277101
    • Filing Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21689024

  • [Patent] 球脊髄性筋萎縮症治療薬2009
    • Inventor(s)
      祖父江元, 勝野雅央, 南山誠
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2009-277101
    • Filing Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Patent] 球脊髄性筋萎縮症治療薬2009
    • Inventor(s)
      祖父江元、勝野雅央、南山誠
    • Industrial Property Rights Holder
      未定
    • Filing Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-17025020

  • [Presentation] 球脊髄性筋萎縮症に対する定量的複合指標SBMAFCの開発2022
    • Author(s)
      橋詰 淳、山田晋一郎、伊藤大輔、岸本祥之、鳥居良太、山本知孝、森田光哉、勝野雅央
    • Organizer
      第63回　日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K07458

  • [Presentation] 2.IgG4自己抗体陽性の難治性慢性炎症性脱髄性多発神経炎（CIDP）患者を対象としたリツキシマブの有効性と安全性評価に関する多施設共同臨床試験2022
    • Author(s)
      飯島正博，清水忍，深見祐樹，田村奈津子，中杤昌弘，安藤昌彦，小池春樹，海田賢一，古賀道明，神田隆，緒方英紀，山﨑亮，吉良潤一，森雅裕，桑原聡，勝野雅央
    • Organizer
      神経免疫班合同班会議
    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Presentation] Presymptomatic exercise ameliorates polyglutamine-expanded protein accumulation and motor dysfunction in a mouse model of SBMA.2021
    • Author(s)
      Katsuno M.
    • Organizer
      16th meeting of Asian-Pacific Society for Neurochemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00527

  • [Presentation] 血管炎性ニューロパチーにおける好中球の行動様式に関する超微形態学的検討2021
    • Author(s)
      小池春樹、毛利尚裕、深見祐樹、飯島正博、勝野雅央
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Presentation] レビー小体型認知症の嗅覚障害2021
    • Author(s)
      勝野雅央
    • Organizer
      36回日本老年精神医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19443

  • [Presentation] Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic ALS2021
    • Author(s)
      Genki Tohnai, Ryoichi Nakamura, Jun Sone, Masahiro Nakatochi, Daichi Yokoi, Masahisa Katsuno, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Satoshi Kuwabara, Koji Abe, Kouichi Mizoguchi, Masahi Aoki, Nobutaka Hattori, Shoji Tsuji, Naoki Atsuta, Gen Sobue
    • Organizer
      PACTALS 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06523

  • [Presentation] In vivo models of pathological TDP-43 transmission2021
    • Author(s)
      井口 洋平, 李 佳益, 天草 善信, 横井 聡, 勝野 雅央
    • Organizer
      第６２回日本神経学会
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Presentation] Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in ALS2021
    • Author(s)
      大岩 康太郎, 渡邊 征爾, 井口 洋平, 勝野 雅央, 山中 宏二
    • Organizer
      第６２回日本神経学会
    • Data Source
      KAKENHI-PROJECT-20H03589

  • [Presentation] Which Ig component is essential as an immunomodulator for CIDP model mice?2021
    • Author(s)
      Iijima M, Fukami Y, Mohri N, Koike H, Murakami H, Nakagawa H, Katsuno M.
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Presentation] レビー小体病ハイリスクコホート2021
    • Author(s)
      勝野雅央
    • Organizer
      第40回日本認知症学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19443

  • [Presentation] Mutation screening of theDNAJC7 gene in Japanese patients with sporadic amyotrophic lateral sclerosis2021
    • Author(s)
      Genki Tohnai, Ryoichi Nakamura, Naoki Atsuta, Masahiro Nakatochi, Naoki Hayashi, Masahisa Katsuno, Yuishin Izumi, Akira Taniguchi, Nobutaka Hattori, Mitsuya Morita, Osamu Kano, Satoshi Kuwabara, Masaya Oda, Koji Abe, Kouichi Mizoguchi, Ryuji Kaji, Gen Sobue
    • Organizer
      PACTALS 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06523

  • [Presentation] 球脊髄性筋萎縮症（SBMA）の女性保因者における臨床的特徴に関する検討2021
    • Author(s)
      鳥居良太、橋詰淳、山田晋一郎、伊藤大輔、岸本祥之、勝野雅央
    • Organizer
      第39回　日本神経治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07458

  • [Presentation] CIDPにおける血清ニューロフィラメント軽鎖濃度と臨床病理所見およびNF155自己抗体との関連2020
    • Author(s)
      深見 祐樹(名古屋大学 神経内科), 飯島 正博, 小池 春樹, 橋詰 淳, 勝野 雅央
    • Organizer
      日本末梢神経学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Presentation] 血管炎における好中球の行動様式に関する超微形態学的検討2020
    • Author(s)
      小池春樹、毛利尚裕、深見祐樹、仁紫了爾、飯島正博、勝野雅央
    • Organizer
      第32回日本神経免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07882

  • [Presentation] Presymptomatic exercise attenuates motor dysfunction in a mouse model of SBMA.2020
    • Author(s)
      蛭薙 智紀， 中辻 秀朗， 佐橋 健太郎， 藤内 玄規， 飯田 円， 山田 晋一郎， 村上 あゆ香， 野田 成哉， 勝野 雅央
    • Organizer
      第61回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-20H00527

  • [Presentation] CIDPにおける電気生理・病理学的所見およびNF155自己抗体と血清ニューロフィラメント濃度との関連2020
    • Author(s)
      深見 祐樹(名古屋大学 神経内科), 飯島 正博, 小池 春樹, 橋詰 淳, 勝野 雅央
    • Organizer
      日本神経生理学会
    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Presentation] CIDPにおける血清ニューロフィラメント軽鎖濃度と臨床病理学およびNF155自己抗体との関連2020
    • Author(s)
      深見 祐樹(名古屋大学 神経内科), 飯島 正博, 小池 春樹, 橋詰 淳, 勝野 雅央
    • Organizer
      日本神経免疫学会
    • Data Source
      KAKENHI-PROJECT-20K07864

  • [Presentation] 日本におけるSOD1遺伝子変異陽性筋萎縮性側索硬化症患者の臨床的特徴2020
    • Author(s)
      中村 亮一，熱田 直樹，林 直毅，藤内 玄規，勝野 雅央，和泉 唯信， 金井 数明， 服部 信孝，谷口 彰, 森田 光哉, 狩野 修, 澁谷 和幹, 桑原 聡, 鈴木 直輝, 青木 正志，阿部 康二, 石原 智彦, 小野寺 理, 梶 龍兒，祖父江 元
    • Organizer
      第61回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Presentation] 日本人孤発性筋萎縮性側索硬化症患者における KIF5A 遺伝子変異の頻度と特徴2020
    • Author(s)
      中村亮一、藤内玄規、熱田直樹、中杤昌弘、林直毅、渡辺宏久、勝野雅央、和泉唯信、谷口彰、 森田光哉、狩野修、桑原聡、織田雅也、阿部康二、青木正志、溝口功一、服部信孝、梶龍兒、祖父江元
    • Organizer
      日本人類遺伝学会第65回大会
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Presentation] ビッグデータからみるALSの臨床像、遺伝子と治療開発の展望2020
    • Author(s)
      熱田 直樹, 中村 亮一, 藤内 玄規, 勝野 雅央, 祖父江 元
    • Organizer
      第61回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Presentation] TDP-43 facilitates exocytosis: unexpected link between ALS and diabetes.2019
    • Author(s)
      Katsuno M.
    • Organizer
      Australia-Japan Joint Neurodegenerative Disease Symposium.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] 唾液メラトニン測定によるレム睡眠行動異常症におけるメラトニン分泌異常の検出2019
    • Author(s)
      中村友彦　今井絵理子　原田裕三子　鈴木将史　藤内玄規　勝野雅央
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Genetic and functional analysis of the KIF5A variants in Japanese patients with sporadic amyotrophic lateral sclerosis.2019
    • Author(s)
      Ryoichi Nakamura, Naoki Atsuta, Genki Tohnai, Masahiro Nakatochi, Naoki Hayashi, Masahisa Katsuno, Yuishin Izumi, Akira Taniguchi, Nobutaka Hattori, Mitsuya Morita, Osamu Kano, Satoshi Kuwabara, Masaya Oda, Koji Abe, Kouichi Mizoguchi, Ryuji Kaji, Gen Sobue, JaCALS
    • Organizer
      30th international symposium on ALS/MND
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Presentation] 唾液メラトニン測定によるパーキンソン病の睡眠障害の検出2019
    • Author(s)
      中村友彦、鈴木将史、上田美紀、今井絵里子、勝野雅央
    • Organizer
      日本臨床検査医学会第58回東海・北陸支部総会
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Elevation of serum creatine kinase before the disease onset of amyotrophic lateral sclerosis2019
    • Author(s)
      Daisuke Ito, Atsushi Hashizume, Yasuhiro Hijikata, Shinichiro Yamada, Yoshiyuki Kishimoto, Hideyuki Moriyoshi, Yohei Iguchi, Madoka Iida, Masahisa Katsuno
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Presentation] 封入体筋炎におけるエクソーム解析2019
    • Author(s)
      勝野雅央、中村亮一、村上あゆ香、野田成哉、木村正剛、熱田直樹
    • Organizer
      多系統蛋白質症(MSP)の疾患概念確立および 診断基準作成、診療体制構築に関する研究班会議
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] Role of late endosome in the formation of TDP-43 cytoplasmic aggregation2019
    • Author(s)
      Yuhei takahashi, Yohei Iguchi, Masahisa Katsuno
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Presentation] TDP-43凝集におけるエンドソームの関わり2019
    • Author(s)
      井口洋平、高橋裕平、李佳益、荒木邦彦、井汲一尋、勝野雅央
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Presentation] TDP-43 regulates early-phase insulin secretion from pancreatic beta cells.2019
    • Author(s)
      Katsuno M.
    • Organizer
      The 22nd US-Japan Cellular and Gene Therapy Conference “Adeno-associated Virus-Mediated Gene Therapy Gene Therapy”.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] Mutation analysis of KIF5A in Japanese patients with amyotrophic lateral sclerosis2019
    • Author(s)
      中村亮一、熱田直樹、藤内玄規、中杤昌弘、林直毅、渡辺宏久、勝野雅央、和泉唯信、谷口彰、服部信孝、森田光哉、狩野修、桑原聡、織田雅也、阿部康二、溝口功一、梶龍兒、祖父江元、JaCALS
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K07973

  • [Presentation] Filamin-A as a novel driver for progressive supra nuclear palsy2019
    • Author(s)
      Koyo Tsujikawa, kohei Hamanaka, Mari Yoshida, Kentaro Sahashi, Satoko Miyatake, Satomi Mihashi, Yohei Iguchi, Yuichi Riku, Shinsuke Ishigaki, Gen Sobue, Naomichi Matsumoto, Masahisa Katsuno
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Presentation] Patisiran, an investigational RNAi therapeutic for patients with hereditary transthyretin-mediated (hATTR) amyloidosis: Phase 3 APOLLO study subanalysis of Japanese patients.2018
    • Author(s)
      Yamashita Y, Sekijima Y, Koike H, Ueda M, Yoshinaga T, Kodaira M, Sobue G, Katsuno M, Singh T, Hashimoto Y, Kadam K, Hou A, Ando Y
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic ALS2018
    • Author(s)
      藤内 玄規, 中村 亮一, 曽根 淳, 中杤 昌弘, 横井 大知, 勝野 雅央, 和泉 唯信, 森田 光哉, 谷口 彰, 桑原 聡, 阿部 康二, 溝口 功一, 青木 正志, 服部 信孝, 辻 省次, 梶 龍兒, 熱田 直樹, 祖父江 元, JaCALS
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] Validation of genetic factors affecting survival in Japanese ALS patients2018
    • Author(s)
      Ryoichi Nakamura, Naoki Atsuta, Genki Tohnai, Masahiro Nakatochi, Naoki Hayashi, Daichi Yokoi, Hirohisa Watanabe, Masahisa Katsuno, et al.
    • Organizer
      29th International Symposium on ALS/MND.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] Evolution of amyloid fibrils in transthyretin familial amyloid polyneuropathy: an ultrastructural study.2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G
    • Organizer
      2018 Peripheral Nerve Society Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Cardiac and peripheral vasomotor autonomic functions in late-onset hereditary ATTR amyloidosis with Val30Met mutation2018
    • Author(s)
      Nakamura T, Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] 多施設共同前向きコホートでみたALS患者に対する気管切開下陽圧換気療法の予後2018
    • Author(s)
      林 直毅, 熱田 直樹, 横井 大知, 中村 亮一, 伊藤 瑞規, 渡辺 宏久, 勝野 雅央, 和泉 唯信, 饗場 郁子, 狩野 修, 谷口 彰, 森田 光哉, 阿部 康二, 金井 数明, 服部 信孝, 青木 正志, 桑原 聡, 梶 龍兒, 祖父江 元, JaCALS
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] Common clinicopathological features in late-onset hereditary ATTR amyloidosis (Ala97Gly, Val94Gly, and Val30Met)2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Yasuda T, Mukai E, Date Y, Shiomi K, Nakazato M, Katsuno M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Validation of genetic factors affecting survival in Japanese ALS patients2018
    • Author(s)
      中村 亮一, 熱田 直樹, 藤内 玄規, 中杤 昌弘, 林 直毅, 横井 大知, 渡辺 宏久, 勝野 雅央, 和泉 唯信, 森田 光哉, 谷口 彰, 服部 信孝, 狩野 修, 織田 雅也, 阿部 康二, 桑原 聡, 溝口 功一, 梶 龍兒, 祖父江 元, JaCALS
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] パーキンソン病と多系統萎縮症における起立時心応答反応の差異の検討2018
    • Author(s)
      中村　友彦、鈴木　将史、上田　美紀、今井　絵里子、勝野　雅央
    • Organizer
      第12回日本パーキンソン病・運動障害疾患学会（MDSJ）コングレス
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] 前頭側頭葉変性症の早期診断へ向けた尾状核体積自動測定システムの開発2018
    • Author(s)
      加藤 隼康, 山下 典生, 渡辺 宏久, 大嶽 れい子, 田中 康博, 小倉 礼, 川畑 和也, 桝田 道人, 横井 孝政, 原 一洋, 中村 亮一, 熱田 直樹, 勝野 雅央, 祖父江 元
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] VCP 遺伝子変異が認められた4 家系の臨床像2018
    • Author(s)
      中村亮一、安藤孝志、原一洋、熱田直樹、勝野雅央
    • Organizer
      多系統蛋白質症(MSP)の疾患概念確立および 診断基準作成、診療体制構築に関する研究班会議
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] 筋萎縮性側索硬化症の脳萎縮様式の多様性と認知機能の関係性2018
    • Author(s)
      加藤 隼康, 渡辺 宏久, 山下 典生, 川畑 和也, 蝦名 潤哉, 大嶽 れい子, 田中 康博, 吉田 有佑, 小倉 礼, 桝田 道人, 原 一洋, 中村 亮一, 熱田 直樹, 勝野 雅央, 祖父江 元
    • Organizer
      第37回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] Evolution of amyloid fibrils in hereditary ATTR amyloidosis: an ultrastructural study2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Association of impaired melatonin secretion with sleep disturbance in multiple system atrophy2018
    • Author(s)
      Tomohiko Nakamura, Masashi Suzuki, Miki Ueda, Eriko Imai, Genki Tohnai, Masahisa Katsuno
    • Organizer
      22nd International Congress of Parkinson's Disease and Movement Disorders
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Cardiac and peripheral vasomotor autonomic functions in hereditary ATTR amyloidosis with non-Val30Met mutation.2018
    • Author(s)
      Koike H, Nakamura T, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno.M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Evolution of amyloid fibrils in hereditary ATTR amyloidosis:an ultrastructural study.2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno.M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] ALSFRS-Rを用いた 筋萎縮性側索硬化症患者の 進行、予後予測と治験デザイン2018
    • Author(s)
      熱田直樹、中村亮一、林直毅、横井大知、伊藤瑞規、渡辺宏久、勝野雅央、和泉唯信、森田光哉、谷口彰、織田雅也、阿部康二、狩野修、桑原聡、青木正志、金井数明、服部信孝、梶龍兒、祖父江元、JaCALS
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09778

  • [Presentation] 球脊髄性筋萎縮症における神経筋システム変性病態2018
    • Author(s)
      勝野雅央
    • Organizer
      第63回日本人類遺伝学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] Cardiac and peripheral vasomotor autonomic functions in hereditary ATTR amyloidosis with Val30Met mutation.2018
    • Author(s)
      13.Nakamura T, Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno.M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Hereditary leukoencephalopathy with brain stem and spinal cord involvement2018
    • Author(s)
      井口 洋平, 熱田 直樹, 勝野 雅央
    • Organizer
      第５９回日本神経学会総会
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Presentation] リバーストランスレーションによるTDP-43の機能解明.2018
    • Author(s)
      勝野雅央
    • Organizer
      第6回日本難病医療ネットワーク学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] ALSFRS-Rを用いた筋萎縮性側索硬化症患者の進行、予後予測と治験デザイン2018
    • Author(s)
      熱田 直樹, 中村 亮一, 林 直毅, 横井 大知, 伊藤 瑞規, 渡辺 宏久, 勝野 雅央, 和泉 唯信, 森田 光哉, 谷口 彰, 織田 雅也, 阿部 康二, 狩野 修, 桑原 聡, 青木 正志, 金井 数明, 服部 信孝, 梶 龍兒, 祖父江 元, JaCALS
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] 多系統萎縮症における睡眠障害におけるメラトニン分泌異常の関与の検討2018
    • Author(s)
      中村友彦　今井絵理子　上田美紀　鈴木将史　藤内玄規　勝野雅央
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Prognosis of Japanese patients with amyotrophic lateral sclerosis according to motor phenotype2018
    • Author(s)
      Naoki Atsuta, Daichi Yokoi, Ryoichi Nakamura, Hazuki Watanabe, Naoki Hayashi, Mizuki Ito, Hirohisa Watanabe, Masahisa Katsuno, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Masaya Oda, Koji Abe, Kouichi Mizoguchi, Osamu Kano, Satoshi Kuwabara, Masashi Aoki, Nobutaka Hattori, Ryuji Kaji, & Gen Sobue, JaCALS
    • Organizer
      PACTALS 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09778

  • [Presentation] Common clinicopathological features in late-onset hereditary ATTR amyloidosis (Ala97Gly, Val94Gly, and Val30Met).2018
    • Author(s)
      Koike H, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Yasuda T, Mukai E, Date Y, Shiomi K, Nakazato M, Katsuno.M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Cardiac and peripheral vasomotor autonomic functions in hereditary ATTR amyloidosis with non-Val30Met mutation2018
    • Author(s)
      Koike H, Nakamura T, Nishi R, Ikeda S, Kawagashira Y, Iijima M, Katsuno M, Sobue G
    • Organizer
      The XVIth International Symposium on Amyloidosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] パーキンソン病の睡眠障害におけるメラトニン分泌異常の関与2017
    • Author(s)
      中村　友彦、鈴木　将史、上田　美紀、今井　絵里子、勝野　雅央
    • Organizer
      第11回パーキンソン病運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] THE ROLE OF TDP-43 SECRETION IN ASSOCIATION WITH EXOSOMES2017
    • Author(s)
      Yohei Iguchi1, 2, Lara Eid1, Martin Parent1, Yuichi Riku2, Kaori Kawai, Mari Yoshida, Masahisa Katsuno, Gen Sobue, Jean-Pierre Julien
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09753

  • [Presentation] Pathological features of NOD B7-2 knockout mice treated by high dose immunoglobulins2017
    • Author(s)
      Iijima M, Nishi R, Ikeda S, Kawagashira Y, Koike H, Katsuno M, Sobue G.
    • Organizer
      XXIII World Congress of Neurology
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Efficacy of immunoglobulins for NOD B7-2 knockout mice.2017
    • Author(s)
      Iijima M, Nishi R, Ikeda S, Kawagashira Y, Koike H, Katsuno M, Sobue G.
    • Organizer
      Peripheral Nerve Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] THE ROLE OF TDP-43 SECRETION IN ASSOCIATION WITH EXOSOMES.2017
    • Author(s)
      Yohei Iguchi, Lara Eid, Martin Parent, Yuichi Riku, Kaori Kawai, Mari Yoshida, Masahisa Katsuno, Gen Sobue, Jean-Pierre Julien
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] Schwann cell and endothelial cell damage in transthyretin familial amyloid polyneuropathy2017
    • Author(s)
      Koike H, Ikeda S, Takahashi M, Kawagashira Y, Iijima M, Misumi Y, Ando Y, Ikeda SI, Katsuno M, Sobue G
    • Organizer
      2017 PNS Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09777

  • [Presentation] Biomarker-based analysis of preclinical progression in motor neuron disease.2017
    • Author(s)
      Masahisa Katsuno
    • Organizer
      The 8th East Asia Neurological Forum (8th EANF).
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] Prognosis of Japanese patients with amyotrophic lateral sclerosis according to motor phenotype2017
    • Author(s)
      Naoki Atsuta, Daichi Yokoi, Ryoichi Nakamura, Hazuki Watanabe, Naoki Hayashi, Mizuki Ito, Hirohisa Watanabe, Masahisa Katsuno, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Masaya Oda, Koji Abe, Kouichi Mizoguchi, Osamu Kano, Satoshi Kuwabara, Masashi Aoki, Nobutaka Hattori, Ryuji Kaji, & Gen Sobue, JaCALS
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09778

  • [Presentation] Clinicopathological features among CIDP subtypes.2017
    • Author(s)
      Ikeda S, Nishi R, Kawagashira Y, Iijima M, Koike H, Katsuno M, Sobue G.
    • Organizer
      Peripheral Nerve Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Association of impaired melatonin secretion with sleep disturbance in Parkinson’s disease2017
    • Author(s)
      Tomohiko Nakamura, Eriko Imai, Miki Ueda, Masashi Suzuki, Genki Tohnai, Masahisa Katsuno
    • Organizer
      XXIII World Congress of Neurology WCN2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Akt signaling pathway is dysregulated in polyglutamine diseases.2017
    • Author(s)
      Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Yutaka Tsutsumi, Hiroaki Adachi, Gen Sobue, Masahisa Katsuno
    • Organizer
      第58回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] Clinical characteristics of familial and sporadic amyotrophic lateral sclerosis patients with G93S mutation in the SOD1 gene.2017
    • Author(s)
      Ryoichi Nakamura, Naoki Atsuta, Genki Tohnai, Daichi Yokoi, Hazuki Watanabe, Naoki Hayashi, Jun Sone, Mizuki Ito, Hirohisa Watanabe, Masahisa Katsuno, Yuishin Izumi, Rina Hashimoto, Ikuko Aiba, Kouichi Mizoguchi, Ryuji Kaji, & Gen Sobue, JaCALS.
    • Organizer
      World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16116

  • [Presentation] Association of impaired melatonin secretion with sleep disturbance in Parkinson’s disease2017
    • Author(s)
      T Nakamura, E Imai, M Ueda, M Suzuki, G Tohnai, M Katsuno
    • Organizer
      International Society for Autonomic Neuroscience (ISAN) 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Akt signaling pathway is dysregulated in polyglutamine diseases.2017
    • Author(s)
      Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Yutaka Tsutsumi, Hiroaki Adachi, Gen Sobue, Masahisa Katsuno
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17H04195

  • [Presentation] Association of impaired melatonin secretion with sleep disturbance in Parkinson’s disease2017
    • Author(s)
      Tomohiko Nakamura, Masashi Suzuki, Miki Ueda, Eriko Imai, Genki Tohnai, Masahisa Katsuno
    • Organizer
      MDS 2017 International Congress
    • Place of Presentation
      Vancouver,　Canada
    • Year and Date
      2017-06-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin 155 and anti-contactin 1 antibodies.2017
    • Author(s)
      Koike H, Kadoya M, Kaida K, Ikeda S, Kawagashira Y, Iijima M, Kato D, Ogata H, Yamasaki R, Matsukawa N, Kira J, Katsuno M, Sobue G.
    • Organizer
      Peripheral Nerve Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] MPAによるニューロパチーとNSVNにおける臨床病理学的特徴についての検討2016
    • Author(s)
      高橋美江、小池春樹、飯島正博、川頭祐一、池田昇平、勝野雅央、祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] 筋生検組織病理検査による神経原性変化の検出2016
    • Author(s)
      木村正剛、中西浩隆、野田成哉、飯島正博、小池春樹、勝野雅央
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Loss of SFPQ, an intra-nuclear counterpart of FUS cause FTLD-like phenotypes.2016
    • Author(s)
      Fujioka Y, Ishigaki S, Yokoi S, Honda D, Okado H, Watanabe H, Katsuno M, Sobue G.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15480

  • [Presentation] 神経変性疾患モデルにおけるタクロリムスとその誘導体の治療効果2016
    • Author(s)
      藤内玄規, 勝野雅央, 足立弘明, 佐橋健太郎, 近藤直英, 中辻秀朗, 飯田円, 祖父江元
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県　横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K15480

  • [Presentation] Potential therapeutic targets in polyglutamine-mediated diseases.2016
    • Author(s)
      Katsuno M.
    • Organizer
      1st International Asidan Symposium on Asida River/Japan
    • Place of Presentation
      ホテル鴎風亭(広島県福山市)
    • Year and Date
      2016-07-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] 家族性アミロイドポリニューロパチーにおける心血管系自律神経障害の検討2016
    • Author(s)
      小池 春樹, 中村 友彦, 池田 昇平, 川頭 祐一, 飯島 正博, 勝野 雅央, 祖父江 元
    • Organizer
      第69回日本自律神経学会総会
    • Place of Presentation
      くまもと県民交流間パレア(熊本県　熊本市)
    • Year and Date
      2016-11-10
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] パーキンソン病の睡眠障害とメラトニン分泌の関連についての検討2016
    • Author(s)
      鈴木将史、中村友彦、上田美紀、岡田暁典、長谷川聖、平山正昭、勝野雅央
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09713

  • [Presentation] CIDPの病型別臨床病理学的特徴2016
    • Author(s)
      池田昇平、高橋美江、川頭祐一、飯島正博、小池春樹、勝野雅央、祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Dysregulated Akt signaling pathway in spinal and bulbar muscular atrophy (SBMA)2016
    • Author(s)
      飯田円，勝野雅央，佐橋健太郎，中辻秀朗，近藤直英，藤内玄規，祖父江元
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県　横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] 家族性アミロイドポリニューロパチー(FAP ATTR Val30Met)におけるシュワン細胞と微小血管内皮細胞の障害様式の検討2016
    • Author(s)
      小池 春樹, 池田 昇平, 高橋 美江, 川頭 祐一, 飯島 正博, 三隅 洋平, 安東 由喜雄, 池田 修一, 勝野 雅央, 祖父江 元
    • Organizer
      第69回日本自律神経学会総会
    • Place of Presentation
      くまもと県民交流間パレア(熊本県　熊本市)
    • Year and Date
      2016-11-10
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] 当院で筋生検を行った封入体筋炎の患者数と臨床的特徴2016
    • Author(s)
      野田成哉、中西浩隆、木村正剛、飯島正博、小池春樹、勝野雅央
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Dysregulated Akt signaling pathway in spinal and bulbar muscular atrophy (SBMA).2016
    • Author(s)
      飯田円，勝野雅央，佐橋健太郎，中辻秀朗，近藤直英，藤内玄規，祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] 抗SRP抗体陽性筋症の臨床病理学的特徴2016
    • Author(s)
      中西浩隆、小池春樹、飯島正博、野田成哉、木村正剛、勝野雅央
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] CIDPモデルマウスの臨床病理学的特徴と免疫療法に対する有効性の検討2016
    • Author(s)
      飯島正博、池田昇平、高橋美江、川頭祐一、小池春樹、勝野雅央、祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Accumulation of phosphorylated tau in neurons in FUS-silenced mice.2016
    • Author(s)
      Ishigaki S, Fujioka Y, Honda D, Yokoi S, Endo K, Okado H, Watanabe H, Katsuno M, Takashima A, Sobue G.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15480

  • [Presentation] 抗neurofascin 155抗体陽性CIDPにおける傍絞輪部の超微形態学的検討2016
    • Author(s)
      小池 春樹, 池田 昇平, 川頭 祐一, 飯島 正博, 角谷 真人, 海田 賢一, 勝野 雅央, 祖父江 元
    • Organizer
      第28回日本神経免疫学会学術集会
    • Place of Presentation
      長崎ブリックホール(長崎県　長崎市）
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] 神経変性疾患の発症前病態と先制治療の開発2016
    • Author(s)
      勝野雅央
    • Organizer
      日本内科学会東海支部主催第66回生涯教育講演会
    • Place of Presentation
      名古屋国際会議場(愛知県　名古屋市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15480

  • [Presentation] IVIgが不応性で、単純血漿交換が奏効したIgG4サブクラス抗neurofascin 155抗体陽性CIDP3例の治療経験2016
    • Author(s)
      服部 誠, 飯島 正博, 熱田 直樹, 伊藤 瑞規, 小池 春樹, 勝野 雅央
    • Organizer
      第34回日本神経治療学会総会
    • Place of Presentation
      米子コンベンションセンター・米子市文化ホール(鳥取県　米子市)
    • Year and Date
      2016-11-04
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] 神経変性疾患モデルにおけるタクロリムスとその誘導体の治療効果2016
    • Author(s)
      藤内玄規, 勝野雅央, 足立弘明, 佐橋健太郎, 近藤直英, 中辻秀朗, 飯田円, 祖父江元
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県　横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] The effect of exercise in a mouse model of spinal and bulbar muscular atrophy.2016
    • Author(s)
      中辻秀朗, 勝野雅央, 近藤直英, 藤内玄規, 佐橋健太郎, 飯田円, 祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Dissection of mechanisms of neuronal degeneration in polyglutamine disease2016
    • Author(s)
      Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Madoka Iida, Masahisa Katsuno, and Gen Sobue
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26461268

  • [Presentation] Motor neuron-specific dynactin-1 knockout mice exhibit ALSlike neurodegeneration2016
    • Author(s)
      Kaori Kawai, Masahisa Katsuno, Kensuke Ikenaka, Yohei Iguchi, Ryu Katsumata, Kunihiko Araki, Fumiaki Tanaka, Gen Sobue
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸国際会議場（兵庫県　神戸市）
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26461269

  • [Presentation] Antisense inhibition of neuronal androgen receptor in spinal and bulbar muscular atrophy2016
    • Author(s)
      Kentaro Sahashi, Masahisa Katsuno, Gene Hung, Hiroaki Adachi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Madoka Iida, C. Frank Bennett, and Gen Sobue
    • Organizer
      第8回NAGOYAグローバルリトリート
    • Place of Presentation
      あいち健康プラザ(愛知県知多郡)
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-26461268

  • [Presentation] トランスレーショナルリサーチ入門:研究が実用になるまで.2016
    • Author(s)
      勝野雅央
    • Organizer
      第4回ヤング・サイエンティスト・シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県　横浜市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] 家族性アミロイドポリニューロパチーにおける血液神経関門の定量的検討2016
    • Author(s)
      小池春樹、池田昇平、高橋美江、川頭祐一、飯島正博、勝野雅央、祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Dissection of mechanisms of neuronal degeneration in polyglutamine disease.2016
    • Author(s)
      佐橋健太郎, 近藤直英, 中辻秀朗, 藤内玄規, 飯田円, 勝野雅央, 祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] IgM-MGUSに伴うニューロパチーの臨床病理学的特徴2016
    • Author(s)
      川頭祐一、池田昇平、高橋美江、飯島正博、小池春樹、勝野雅央、祖父江元
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09693

  • [Presentation] Application of biomarkers for early-stage of spinal and bulbar muscular atrophy to clincal trials2016
    • Author(s)
      勝野雅央
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県　神戸市)
    • Year and Date
      2016-05-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Intracerebroventricular administration of antisense oligonucleotides improves disease phenotypes in SBMA mice.2015
    • Author(s)
      Sahashi K, Katsuno M, Hung G, Adachi H, Kondo N, Nakatsuji H, Tohnai G, Iida M, Bennett CF, Sobue G.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Expression and role of TFEB in spinal and bulbar muscular atrophy2015
    • Author(s)
      藤内 玄規, 足立 弘明, 勝野 雅央, 近藤 直英, 宮崎 雄, 飯田 円, 中辻 秀朗, 丁 瑩, 渡辺 宏久, 祖父江 元.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] The effects of pioglitazone on spinal and bulbar muscular atrophy.2015
    • Author(s)
      Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Watanabe H, Yamamoto M, Kishida K, Sobue G.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Impaired muscular creatine metabolism in spinal and bulbar muscular atrophy (SBMA).2015
    • Author(s)
      Hijikata Y, Katsuno M, Suzuki K, Banno H, Hashizume A, Yamada S, Sobue G.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-15K15337

  • [Presentation] Antisense inhibition of neuronal androgen receptor in spinal and bulbar muscular atrophy.2015
    • Author(s)
      Sahashi K, Katsuno M, Hung G, Adachi H, Kondo N, Nakatsuji H, Tohnai G, Iida M, Bennett CF, Sobue G
    • Organizer
      第33回日本神経治療学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Dysregulated nuclear factor-κB (NFκB) signaling in spinal and bulbar muscular atrophy (SBMA).2015
    • Author(s)
      Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Tohnai G, Sobue G.
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-26
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] 球脊髄性筋萎縮症患者における呼吸 機能－筋萎縮性側索硬化症との比較－2015
    • Author(s)
      山田晋一郎、勝野雅央、鈴木啓介、 橋詰淳、土方靖浩、祖父江元
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-15K15337

  • [Presentation] 運動ニューロン疾患の分子病態解明に基づく治療標的開発.2015
    • Author(s)
      勝野雅央.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Disruped muscle uptake of creatine in spinal and bulbar muscular atrophy.2015
    • Author(s)
      Hijikata Y, Katsuno M, Hashizume A,　Yamada S, Inagaki T, Suzuki K, Banno H, Sobue G.
    • Organizer
      The 26th International Symposium on ALS/MND
    • Place of Presentation
      Orland, USA
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] 運動ニューロン疾患の分子病態解明に基づく治療標的開発.2015
    • Author(s)
      勝野雅央.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-05-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15337

  • [Presentation] dynactin-1ノックアウトマウスにおける進行性運動機能障害2015
    • Author(s)
      河合香里、池中建介、勝野雅央、井口洋平、荒木邦彦、田中章景、祖父江元
    • Organizer
      第33回日本神経治療学会総会
    • Place of Presentation
      名古屋国際会議場（愛知県名古屋市）
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26461269

  • [Presentation] Disruped muscle uptake of creatine in spinal and bulbar muscular atrophy2015
    • Author(s)
      Hijikata Y, Katsuno M, Suzuki K, Banno H, Hashizume A, Yamada S, Sobue G.
    • Organizer
      The 26th International Symposium on ALS/MND
    • Place of Presentation
      Orlando(USA)
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15337

  • [Presentation] Pathogenesis of neurodegeneration in motor neuron-specific dynactin-1 knockout mice2015
    • Author(s)
      河合香里、池中建介、勝野雅央、井口洋平、勝又竜、田中章景、祖父江元
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場（兵庫県神戸市）
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26461269

  • [Presentation] Antisense inhibition of neuronal androgen receptor in spinal and bulbar muscular atrophy2015
    • Author(s)
      Kentaro Sahashi, Masahisa Katsuno, Gene Hung, Hiroaki Adachi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Madoka Iida, C. Frank Bennett, and Gen Sobue
    • Organizer
      第33回日本神経治療学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26461268

  • [Presentation] Cell cycle inhibitor ameliorates motor neuron degeneration induced by polyglutamine-expanded androgen receptor.2015
    • Author(s)
      Katsuno M, Adachi H, Sahashi K, Kondo N, Iida M, Nakatsuji H, Tohnai G, Sobue G.
    • Organizer
      The 26th International Symposium on ALS/MND
    • Place of Presentation
      Orland, USA
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] dynactin-1ノックアウトマウスを用いた孤発性ALSの病態解析2015
    • Author(s)
      河合香里、池中建介、勝野雅央、井口洋平、勝又竜、田中章景、祖父江元
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ（新潟県新潟市）
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461269

  • [Presentation] 球脊髄性筋萎縮症モデルにおけるタクロリムス誘導体の治療効果2015
    • Author(s)
      藤内玄規, 足立弘明, 勝野雅央, 佐橋健太郎, 近藤直英, 中辻秀朗, 飯田円, 祖父江 元.
    • Organizer
      第33回日本神経治療学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26293206

  • [Presentation] Pathogenesis of selective neurodegeneration in polyglutamine-mediated motor neuron disease2014
    • Author(s)
      Katsuno M, Sobue G
    • Organizer
      International symposium. New Frontier of Molecular Neuropathology 2014
    • Place of Presentation
      Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Molecular pathway and therapeutic strategies for motor neuron diseases.2014
    • Author(s)
      Katsuno M.
    • Organizer
      The 5th East Asia Neurology Forum (EANF)
    • Place of Presentation
      Kaoshiung, Taiwan
    • Year and Date
      2014-04-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Pathogenesis of selective neurodegeneration in polyglutamine-mediated motor neuron disease.2014
    • Author(s)
      Katsuno, M., Sobue, G.
    • Organizer
      New Frontier of Molecular Neuropathology 2014
    • Place of Presentation
      東京大学本郷キャンパス　伊藤国際学術研究センター、東京都文京区
    • Invited
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] 神経変性疾患に対する医師主導治験.2014
    • Author(s)
      勝野雅央.
    • Organizer
      第11回医薬品評価フォーラム
    • Place of Presentation
      東京都渋谷区日本薬学会 長井記念館
    • Year and Date
      2014-04-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Pathogenesis of selective neurodegeneration in polyglutamine-mediated motor neuron disease2014
    • Author(s)
      Katsuno M, Sobue G.
    • Organizer
      International symposium. New Frontier of Molecular Neuropathology 2014
    • Place of Presentation
      Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] 神経変性疾患に対する医師主導治験.2014
    • Author(s)
      勝野雅央.
    • Organizer
      第11回医薬品評価フォーラム
    • Place of Presentation
      東京都渋谷区日本薬学会 長井記念館
    • Year and Date
      2014-04-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670440

  • [Presentation] Molecular pathway and therapeutic strategies for motor neuron diseases.2014
    • Author(s)
      Katsuno M.
    • Organizer
      The 5th East Asia Neurology Forum (EANF)
    • Place of Presentation
      Kaoshiung, Taiwan
    • Year and Date
      2014-04-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670440

  • [Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
    • Author(s)
      Adachi, H., Qiang, Q., Hunag, Z., Jinag, Y.M., Katsuno, M., Kondo, N., Miyazaki, Y., Iida, M., Tohnai, G., Nakatsuji, H., Sobue, G.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
    • Author(s)
      Adachi, H., Qiang, Q., Hunag, Z., Jinag, Y.M., Katsuno, M., Kondo, N., Miyazaki, Y., Iida, M., Tohnai, G., Nakatsuji, H., Sobue, G.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Heat shock factor-1 (Hsf-1) controls pathological lesion distribution of polyglutamine-induced motor neuron disease.2013
    • Author(s)
      Kondo, N., Katsuno, M., Adachi, H., Minamiyama, M., Matsumoto, S., Nakatsuji, H., Miyazaki, Y., Iida, M., Tohnai, G., Sobue, G.
    • Organizer
      The 24th International Symposium on ALS/MND
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD2013
    • Author(s)
      Fujioka Y, Ishigaki S, Udagawa T, Honda D, Katsuno M, Sobue G.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Neurobiological Study of Postmortem Brain from Brain Bank : for the study of spinal disorders2013
    • Author(s)
      Katsuno M
    • Organizer
      Neuro2013
    • Place of Presentation
      Kyoto International Conference Center, Kyoto City, Japan
    • Year and Date
      2013-06-22
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
    • Author(s)
      Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
    • Author(s)
      Adachi, H., Qiang, Q., Hunag, Z., Jinag, Y.M., Katsuno, M., Kondo, N., Miyazaki, Y., Iida, M., Tohnai, G., Nakatsuji, H., Sobue, G.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Heat shock factor-1 (Hsf-1) controls pathological lesion distribution of polyglutamine-induced motor neuron disease.2013
    • Author(s)
      Kondo, N., Katsuno, M., Adachi, H., Minamiyama, M., Matsumoto, S., Nakatsuji, H., Miyazaki, Y., Iida, M., Tohnai, G., Sobue, G.
    • Organizer
      The 24th International Symposium on ALS/MND
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease2013
    • Author(s)
      Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Genistein, a natural product derived from soybeans2013
    • Author(s)
      Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G.
    • Organizer
      ameliorates polyglutamine-mediated motor neuron disease. Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
    • Author(s)
      Hlievski, K., Henley, C.L., Fu, M., Katsuno, M., Adachi, H., Sobue, G., Breedlove, S.M., Jordan, C.L.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego,USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] 運動ニューロン疾患に対する分子標的治療法の開発2013
    • Author(s)
      勝野雅央
    • Organizer
      第4回神経科学と構造生物学の融合研究会
    • Place of Presentation
      自然科学研究機構岡崎コンファレンスセンター,岡崎市
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
    • Author(s)
      Hlievski, K., Henley, C.L., Fu, M., Katsuno, M., Adachi, H., Sobue, G., Breedlove, S.M., Jordan, C.L.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
    • Author(s)
      Hlievski, K., Henley, C.L., Fu, M., Katsuno, M., Adachi, H., Sobue, G., Breedlove, S.M., Jordan, C.L.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease2013
    • Author(s)
      Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] FUS regulates alternative splicing patterns of Mapt by cooperating with PSF/SFPQ : a novel link between FUS and Tau in the pathogenesis of ALS and FTLD2013
    • Author(s)
      Ishigaki S, Fujioka Y, Udagawa T, Honda D, Katsuno M, Sobue G.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Neurobiological Study of Postmortem Brain from Brain Bank : for the study of spinal disorders2013
    • Author(s)
      Katsuno M.
    • Organizer
      Neuro2013
    • Place of Presentation
      Kyoto International Conference Center, Kyoto City, Japan
    • Year and Date
      2013-06-22
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
    • Author(s)
      Hlievski K, Henley CL, Fu M, Katsuno M, Adachi H, Sobue G, Breedlove SM, Jordan CL.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Heat shock factor-1 (Hsf-1) controls pathological lesion distribution of polyglutamine-induced motor neuron disease.2013
    • Author(s)
      Kondo, N., Katsuno, M., Adachi, H., Minamiyama, M., Matsumoto, S., Nakatsuji, H., Miyazaki, Y., Iida, M., Tohnai, G., Sobue, G.
    • Organizer
      The 24th International Symposium on ALS/MND
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Longitudinal changes of outcome measures in spinal and bulbar muscular atrophy2012
    • Author(s)
      Hashizume A, Katsuno M, Banno H, Suzuki K, Suga N, Mano T, Atsuta N, Oe H, Watanabe H, Tanaka F, SobueG.
    • Organizer
      23rd International Symposium on ALS/MND
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Molecular pathogenesis and therapy of polyglutamine-induced motor neuron degeneration2012
    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Doi H, Kondo N, Miyazaki Y, Iida M, Tanaka F, Sobue G.
    • Organizer
      35th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya Congress Center, Nagoya City, Japan
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse2012
    • Author(s)
      Adachi H, Doi H, Katsuno M, Matsumoto S, Kondo N, Miyazaki Y, Tohnai G, Iida M, Tanaka F, Sobue G.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] CGRP1 is the new therapeutic target for SBMA (Spinal and Bulbar Muscular Atrophy)2012
    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
    • Organizer
      11th Biennial Meeting of the Asian Pacific Society for Neurochemistry
    • Place of Presentation
      Kobe International Conference Center, Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway2012
    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Loss of TDP-43 results in age-dependent progressive motor impairment and neuropathological alterations, mimicking motor neuron disease2012
    • Author(s)
      Iguchi Y, Katsuno M, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Tanaka F, Sobue G.
    • Organizer
      23rd International Symposium on ALS/MND
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
    • Author(s)
      Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu SI, Sobue G
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse2012
    • Author(s)
      Adachi H, Doi H, Katsuno M, Matsumoto S, Kondo N, Miyazaki Y, Tohnai G, Iida M, Tanaka F, Sobue G
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] 筋萎縮性側索硬化症、及びそのモデルマウスの腰髄におけるリン酸化Cofilinの評価2012
    • Author(s)
      勝又 竜, 勝野雅央, 田中章景, 祖父江元
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway.2012
    • Author(s)
      Minamiyama, M., Katsuno, M., Adachi, H., Doi, H., Kondo, N., Iida, M., Ishigaki, S., Fujioka, Y., Matsumoto, S., Miyazaki, Y., Tanaka, F., Kurihara, H., Sobue, G.
    • Organizer
      Neuroscience 2012.
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Muscle dysfunction may underlie androgen-dependent motor dysfunction in two mouse models of SBMA.2012
    • Author(s)
      Oki K, Adachi H, Katsuno M, Breedlove M, Sobue G. Wiseman RW, Jordan CL.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA)2012
    • Author(s)
      Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G.
    • Organizer
      23rd International Symposium on ALS/MND
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Comparison of Fus-regulating gene expression and alternative splicing profiles among different cell lineages in the central nervous system.2012
    • Author(s)
      Ishigaki S, Fujioka Y, Masuda A, Iguchi Y, Katsuno M, Ohno K, Sobue G.
    • Organizer
      42nd Society for Neuroscience annual meeting
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse2012
    • Author(s)
      Adachi H, Doi H, Katsuno M, Matsumoto S, Kondo N, Miyazaki Y, Tohnai G, Iida M, Tanaka F, Sobue G
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway.2012
    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Loss of TDP-43 Results In Age-dependent Progressive Motor Impairment And Neuropathological Alterations, Mimicking Motor Neuron Disease.2012
    • Author(s)
      Iguchi Y, Katsuno M, Niwa JI, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Sobue G.
    • Organizer
      24th ALS/MND international symposium.
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2012-12-04
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway2012
    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Comparison of Fus-regulating gene expression and alternative splicing profiles among different cell lineages in the central nervous system2012
    • Author(s)
      Ishigaki S, Fujioka Y, Masuda A, Iguchi Y, Katsuno M, Ohno K, Sobue G.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA).2012
    • Author(s)
      Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G.
    • Organizer
      23rd International Symposium on ALS/MND.
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA)2012
    • Author(s)
      Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G
    • Organizer
      23rd International Symposium on ALS/MND
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] 運動ニューロン特異的TDP-43ノックアウトマウスの病態解析2012
    • Author(s)
      井口洋平, 勝野雅央, 丹羽淳一, 高木伸之介, 田中章景, 祖父江元
    • Organizer
      第53回日本神経学会学術大会.
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-22390175

  • [Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse.2012
    • Author(s)
      Adachi, H., Doi, H., Katsuno, M., Matsumoto, S., Kondo, N., Miyazaki, Y., Tohnai, G., Iida, M., Tanaka, F., Sobue, G.
    • Organizer
      Neuroscience 2012.
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway2012
    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2.2012
    • Author(s)
      Miyazaki, Y., Adachi, H., Katsuno, M., Tanaka, F., Muramatsu, S.I., Sobue, G.
    • Organizer
      Neuroscience 2012.
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
    • Author(s)
      Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu SI, Sobue G
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21229011

  • [Presentation] 運動ニューロンの老化と変性2012
    • Author(s)
      勝野雅央
    • Organizer
      第34回日本生物学的精神医学会シンポジウム『老いを科学する―神経変性の視点から』
    • Place of Presentation
      神戸国際会議場,神戸市
    • Year and Date
      2012-09-29
    • Data Source
      KAKENHI-PROJECT-24659428

  • [Presentation] 運動ニューロンの老化と変性.2012
    • Author(s)
      勝野雅央.
    • Organizer
      第34回日本生物学的精神医学会シンポジウム『老いを科学する―神経変性の視点から』
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2012-09-29
    • Invited
    • Data Source
      KAKENHI-PLANNED-22110005

  • [Presentation] Longitudinal changes of outcome measures in spinal and bulbar muscular atrophy.2012
    • Author(s)
      Hashizume A, Katsuno M, Banno H, Suzuki K, Suga N, Mano T, Atsuta N, Oe H, Watanabe H, Tanaka F, Sobue G.
    • Organizer
      23rd International Symposium on ALS/MND.
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23390230

  • [Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
    • Author(s)
      Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu SI, Sobue G.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA