Iguchi Yohei 井口洋平

… Alternative Names

IGUCHI YOHEI 井口洋平

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Researcher Number	80790659
Other IDs	https://orcid.org/0000-0001-7434-9801
Affiliation (Current)	2023: 名古屋大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2018 – 2022: 名古屋大学, 医学部附属病院, 助教 2017: 名古屋大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields / Basic Section 52020:Neurology-related / Neurology / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator ALS / FTLD / TDP-43 / 筋萎縮性側索硬化症 / TBK1 / 前頭側頭葉変性症 / polysome解析 / 異常タンパク凝集 / TDP-43伝搬 / 凝集タンパク伝播 … More / ニューロン / オリゴデンデロサイト / TDP-43伝播 / タンパク伝播 / 遠位型遺伝性運動ニューロパチー / SLC5A7 … More Except Principal Investigator 運動ニューロン疾患 / シナプス / TDP-43 / 運動ニューロン / 神経変性疾患 / 神経活動 / アンチセンス核酸 / シヌクレイン / エクソサイトーシス / インスリン / DNAメチル化 / Src / アンドロゲン受容体 / カルシウムチャンネル / エクソサイト-シス / DREADD / エクソソーム / 後根神経節 / 脊髄性筋萎縮症 / 核酸 / 髄液 / 運動ニューロン変性 / RNA / 神経分化 / 胎児 / ライフステージ / 球脊髄性筋萎縮症 / 早期病態 / 転写障害 / ミトコンドリア / 運動 / RNAseq / ポリグルタミン / タンパク質凝集体 / 神経変性 / 筋萎縮性側索硬化症 / iPS細胞 / CRISPR/Cas9 / FUS / レビー小体病型認知症 / パーキンソン病 / 神経回路 / 嗅球 / 視覚野 / カルシウムイメージング / α-シヌクレイン / トランスオミックス / コホート Less

Development of neuronal aggregates-targeted therapeutics
- Principal Investigator
  
  佐橋健太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagoya University
Study of synaptic pahtology caused by FUS in amyotrophic lateral sclerosis
- Principal Investigator
  
  横井聡
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagoya University
遠位型遺伝性運動ニューロパチー７型の病態解明と病態抑止療法の開発Principal Investigator
- Principal Investigator
  
  井口洋平
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Wide-field Ca imaging and trans-omics for mouse model of Lewy body disease
- Principal Investigator
  
  勝野雅央
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
超早期ライフステージに着目した神経変性疾患の時空間特異性の解明
- Principal Investigator
  
  勝野雅央
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
孤発性ALSにおける凝集型TDP-43の生体内伝播メカニズムの解明Principal Investigator
- Principal Investigator
  
  井口洋平
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagoya University
Understanding of defective developmental gene regulation responsible for motor neuron degeneration
- Principal Investigator
  
  Kentaro Sahashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University
Discovery of novel target and disease modifying therapy for ALS/FTLD using neuro-specific transcriptome analysisPrincipal Investigator
- Principal Investigator
  
  IGUCHI YOHEI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Elucidation of defective neural communication in motor neuron diseases
- Principal Investigator
  
  Katsuno Masahisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] Pharma Medica2021
- Author(s)
  井口洋平、勝野雅央
- Total Pages
  6
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-20H03589
[Journal Article] Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology2022
- Author(s)
  Tsujikawa K,Hamanaka K, Riku Y, Hattori Y, Hara N, Iguchi Y,Miyata T, Sobue G, Matsumoto N, Sahashi K, Katsuno M, et al.
- Journal Title
  
  Sci Adv
  
  Volume: -
- DOI
  10.1126/sciadv.abm5029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00527
[Journal Article] Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells2021
- Author(s)
  Kanda Mitsuro、Shimizu Dai、Nakamura Shunsuke、Sawaki Koichi、Umeda Shinichi、Miwa Takashi、Tanaka Haruyoshi、Inokawa Yoshikuni、Hattori Norifumi、Hayashi Masamichi、Tanaka Chie、Nakayama Goro、Iguchi Yohei、Katsuno Masahisa、Kodera Yasuhiro
- Journal Title
  
  Oncogene
  
  Volume: 40 Pages: 5495-5504
- DOI
  10.1038/s41388-021-01945-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03589, KAKENHI-PROJECT-20H03750
[Journal Article] The wide-ranging clinical and genetic features in Japanese families with valosin-containing protein proteinopathy2021
- Author(s)
  Ando T, Nakamura R, Kuru S, Yokoi D, Atsuta N, Koike H, Suzuki M, Hara K, Iguchi Y, Harada Y, Yoshida Y, Hattori M, Murakami A, Noda S, Kimura S, Sone J, Nakamura T, Goto Y, Mano K, Okada H, Okuda S, Nishino I, Ogi T, Sobue G, Katsuno M
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 100
- DOI
  10.1016/j.neurobiolaging.2020.10.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-20H03589
[Journal Article] Exploring the factors underlying remyelination arrest by studying the post‐transcriptional regulatory mechanisms of cystatin F gene2021
- Author(s)
  Li Jiayi、Durose Wilaiwan Wisessmith、Ito Junko、Kakita Akiyoshi、Iguchi Yohei、Katsuno Masahisa、Kunisawa Kazuo、Shimizu Takeshi、Ikenaka Kazuhiro
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 157 Pages: 2070-2090
- DOI
  10.1111/jnc.15190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03589
[Journal Article] Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration2021
- Author(s)
  Riku Yuichi、Seilhean Danielle、Duyckaerts Charles、Boluda Susana、Iguchi Yohei、Ishigaki Shinsuke、Iwasaki Yasushi、Yoshida Mari、Sobue Gen、Katsuno Masahisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Pages: 3843-3843
- DOI
  10.3390/ijms22083843
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16586, KAKENHI-PROJECT-20H03589
[Journal Article] Significance of Oligomeric and Fibrillar Species in Amyloidosis: Insights into Pathophysiology and Treatment2021
- Author(s)
  Koike Haruki、Iguchi Yohei、Sahashi Kentaro、Katsuno Masahisa
- Journal Title
  
  Molecules
  
  Volume: 26 Pages: 5091-5091
- DOI
  10.3390/molecules26165091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03589
[Journal Article] Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis2020
- Author(s)
  Ikenaka K, Ishigaki S, Iguchi Y, Kawai K, Fujioka Y, Yokoi S, Abdelhamid RF, Nagano S, Mochizuki H, Katsuno M, Sobue G.
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 79 Pages: 370-377
- DOI
  10.1093/jnen/nlaa003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09690, KAKENHI-PROJECT-17K09753, KAKENHI-PROJECT-18K07367, KAKENHI-PROJECT-20H03589
[Journal Article] Aggresome formation and liquid?liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 432020
- Author(s)
  Watanabe Seiji、Inami Hidekazu、Oiwa Kotaro、Murata Yuri、Sakai Shohei、Komine Okiru、Sobue Akira、Iguchi Yohei、Katsuno Masahisa、Yamanaka Koji
- Journal Title
  
  Cell Death & Disease
  
  Volume: 11 Pages: 909-909
- DOI
  10.1038/s41419-020-03116-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-19KK0214, KAKENHI-PROJECT-20H03589, KAKENHI-PROJECT-18H02740, KAKENHI-PROJECT-17H04986
[Journal Article] NUS1 mutation in a family with epilepsy, cerebellar ataxia, and tremor2020
- Author(s)
  Araki Kunihiko、Nakamura Ryoichi、Ito Daisuke、Kato Kohji、Iguchi Yohei、Sahashi Kentaro、Toyama Miho、Hamada Kensuke、Okamoto Nobuhiko、Wada Yoshinao、Nakamura Tomohiko、Ogi Tomoo、Katsuno Masahisa
- Journal Title
  
  Epilepsy Research
  
  Volume: 164 Pages: 106371-106371
- DOI
  10.1016/j.eplepsyres.2020.106371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03589
[Journal Article] Therapeutic monoclonal antibody targeting of neuronal pentraxin receptor to control metastasis in gastric cancer2020
- Author(s)
  Kanda Mitsuro、Shimizu Dai、Sawaki Koichi、Nakamura Shunsuke、Umeda Shinichi、Miwa Takashi、Tanaka Haruyoshi、Tanaka Chie、Hayashi Masamichi、Iguchi Yohei、Yamada Suguru、Katsuno Masahisa、Kodera Yasuhiro
- Journal Title
  
  Molecular Cancer
  
  Volume: 19 Pages: 131-131
- DOI
  10.1186/s12943-020-01251-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03589
[Journal Article] TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.2019
- Author(s)
  Araki Kunihiko、(他10名）、Ishigaki Shinsuke、Nakamichi Yoko、Tsunekawa Shin、Seino Yusuke、Yamamoto Akiko、Takayama Yasunori、Hidaka Shihomi、Tominaga Makoto、Ohara-Imaizumi Mica、Suzuki Atsushi、Ishiguro Hiroshi、Enomoto Atsushi、Yoshida Mari、Arima Hiroshi、Muramatsu Shin-ichi、Sobue Gen、Katsuno Masahisa
- Journal Title
  
  J Clin Invest.
  
  Volume: 129 Pages: 3578-3593
- DOI
  10.1172/jci124481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07367, KAKENHI-WRAPUP-19H05447, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17K08547, KAKENHI-PROJECT-17K09753
[Journal Article] Elevated serum creatine kinase in the early stage of sporadic amyotrophic lateral sclerosis2019
- Author(s)
  Ito D, Hashizume A, Hijikata Y, Yamada S, Iguchi Y, Iida M, Kishimoto Y, Moriyoshi H, Hirakawa A, Katsuno M.
- Journal Title
  
  Journal of Neurology
  
  Volume: 266 Pages: 2952-2961
- DOI
  10.1007/s00415-019-09507-6
- NAID
  120006786260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-17K09753, KAKENHI-PROJECT-18K15361
[Journal Article] Preclinical progression of neurodegenerative diseases.2018
- Author(s)
  Katsuno M, Sahashi K, Iguchi Y, Hashizume A
- Journal Title
  
  Nagoya J Med Sci
  
  Volume: 80 Pages: 289-298
- NAID
  120006502462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09753
[Journal Article] Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes.2017
- Author(s)
  Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno H, Sobue G.
- Journal Title
  
  Cell Report
  
  Volume: 18 Pages: 1118-1131
- DOI
  10.1016/j.celrep.2017.01.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01568, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117007, KAKENHI-PROJECT-26290016, KAKENHI-PROJECT-16K15480, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K14569, KAKENHI-PROJECT-17K09753, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-15H04278, KAKENHI-PLANNED-26117004, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K06793, KAKENHI-PROJECT-15K09310
[Presentation] Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in ALS2021
- Author(s)
  大岩康太郎, 渡邊征爾, 井口洋平, 勝野雅央, 山中宏二
- Organizer
  第６２回日本神経学会
- Data Source
  KAKENHI-PROJECT-20H03589
[Presentation] In vivo models of pathological TDP-43 transmission2021
- Author(s)
  井口洋平, 李佳益, 天草善信, 横井聡, 勝野雅央
- Organizer
  第６２回日本神経学会
- Data Source
  KAKENHI-PROJECT-20H03589
[Presentation] ALSのマウスモデルの有用性と特性2020
- Author(s)
  井口洋平
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03589
[Presentation] ALSのマウスモデルの有用性と特性2020
- Author(s)
  井口洋平
- Organizer
  第61回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00527
[Presentation] Secretion and propagation of TDP-43 as a therapeutic target for ALS.2020
- Author(s)
  Yohei Iguchi
- Organizer
  第43回日本神経科学大会 (Neuro2020)
- Data Source
  KAKENHI-PROJECT-20H03589
[Presentation] Secretion and propagation of TDP-43 as a therapeutic target for ALS.2020
- Author(s)
  Yohei Iguchi
- Organizer
  第43回日本神経科学大会 (Neuro2020)
- Invited
- Data Source
  KAKENHI-PROJECT-20H00527
[Presentation] TDP-43凝集におけるエンドソームの関わり2019
- Author(s)
  井口洋平、高橋裕平、李佳益、荒木邦彦、井汲一尋、勝野雅央
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Elevation of serum creatine kinase before the disease onset of amyotrophic lateral sclerosis2019
- Author(s)
  Daisuke Ito, Atsushi Hashizume, Yasuhiro Hijikata, Shinichiro Yamada, Yoshiyuki Kishimoto, Hideyuki Moriyoshi, Yohei Iguchi, Madoka Iida, Masahisa Katsuno
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Filamin-A as a novel driver for progressive supra nuclear palsy2019
- Author(s)
  Koyo Tsujikawa, kohei Hamanaka, Mari Yoshida, Kentaro Sahashi, Satoko Miyatake, Satomi Mihashi, Yohei Iguchi, Yuichi Riku, Shinsuke Ishigaki, Gen Sobue, Naomichi Matsumoto, Masahisa Katsuno
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Role of late endosome in the formation of TDP-43 cytoplasmic aggregation2019
- Author(s)
  Yuhei takahashi, Yohei Iguchi, Masahisa Katsuno
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Exosome pathway: a key for clearance of pathological TDP-432018
- Author(s)
  Yohei Iguchi
- Organizer
  第５９回日本神経学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Hereditary leukoencephalopathy with brain stem and spinal cord involvement2018
- Author(s)
  井口洋平, 熱田直樹, 勝野雅央
- Organizer
  第５９回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] THE ROLE OF TDP-43 SECRETION IN ASSOCIATION WITH EXOSOMES.2017
- Author(s)
  Yohei Iguchi, Lara Eid, Martin Parent, Yuichi Riku, Kaori Kawai, Mari Yoshida, Masahisa Katsuno, Gen Sobue, Jean-Pierre Julien
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04195
[Presentation] Emerging roles of exosomes in TDP-43 proteinopathy2017
- Author(s)
  Yohei Iguchi
- Organizer
  第60回日本神経化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04195
[Presentation] Exosome secretion is a key pathway for clearance of pathological TDP-432017
- Author(s)
  Yohei Iguchi
- Organizer
  第40回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Exosome secretion is a key pathway for clearance of pathological TDP-432017
- Author(s)
  Yohei Iguchi
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H04195
[Presentation] THE ROLE OF TDP-43 SECRETION IN ASSOCIATION WITH EXOSOMES2017
- Author(s)
  Yohei Iguchi1, 2, Lara Eid1, Martin Parent1, Yuichi Riku2, Kaori Kawai, Mari Yoshida, Masahisa Katsuno, Gen Sobue, Jean-Pierre Julien
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09753
[Presentation] Emerging roles of exosomes in TDP-43 proteinopathy2017
- Author(s)
  Yohei Iguchi
- Organizer
  第60回日本神経化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09753

1. Katsuno Masahisa (50402566)

# of Collaborated Projects: 9 results

# of Collaborated Products: 25 results
2. Kentaro Sahashi (90710103)

# of Collaborated Projects: 8 results

# of Collaborated Products: 5 results
3. 横井聡 (30815460)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 橋詰淳 (00637689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 蛭薙智紀 (00927527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KODERA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. WATANABE Hirohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. TANABE hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. Aoki Ichio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 長野清一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 石垣診祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 田中千恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 神田光郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 清水大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 熱田直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 中村亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 祖父江元

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 今泉美佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 飯田円

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 陸雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 祖父江顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 山中宏二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 渡邊征爾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 岡田洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 岡野栄之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 岡戸晴生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 高島明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 佐原成彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iguchi Yohei 井口 洋平

IGUCHI YOHEI 井口 洋平

Research Projects

Research Products

Co-Researchers

Development of neuronal aggregates-targeted therapeutics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of synaptic pahtology caused by FUS in amyotrophic lateral sclerosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遠位型遺伝性運動ニューロパチー７型の病態解明と病態抑止療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Wide-field Ca imaging and trans-omics for mouse model of Lewy body disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

超早期ライフステージに着目した神経変性疾患の時空間特異性の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

孤発性ALSにおける凝集型TDP-43の生体内伝播メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding of defective developmental gene regulation responsible for motor neuron degeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of novel target and disease modifying therapy for ALS/FTLD using neuro-specific transcriptome analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of defective neural communication in motor neuron diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Pharma Medica2021

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[Journal Article] Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology2022

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[Journal Article] Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells2021

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[Journal Article] The wide-ranging clinical and genetic features in Japanese families with valosin-containing protein proteinopathy2021

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[Journal Article] Exploring the factors underlying remyelination arrest by studying the post‐transcriptional regulatory mechanisms of cystatin F gene2021

Iguchi Yohei 井口洋平

IGUCHI YOHEI 井口洋平