Kugita Masanori 釘田雅則

… Alternative Names

Researcher Number	50440681
Other IDs
Affiliation (Current)	2021: 藤田医科大学, 疾患モデル教育研究サポートセンター, 講師
Affiliation (based on the past Project Information) *help	2018 – 2019: 藤田医科大学, 疾患モデル教育研究サポートセンター, 講師 2018: 藤田医科大学, 疾患モデル教育研究施設, 講師 2017: 藤田保健衛生大学, 大学共同利用機関等の部局等, 講師 2016: 藤田保健衛生大学, 疾患モデル教育研究施設, 講師 2010 – 2015: 藤田保健衛生大学, 疾患モデル教育研究センター, 助教
Review Section/Research Field	Principal Investigator Experimental pathology / Eating habits / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Experimental pathology / Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator 多発性嚢胞腎症 / RXR / 繊毛病 / ビタミンA / ビタミンK / ネフロン癆 Except Principal Investigator 多発性嚢胞腎 / 細胞増殖 / 慢性腎臓病 / 多発性嚢胞腎症 … More

Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.Ongoing
- Principal Investigator
  
  長尾静子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
食事性刺激に起因するDNA変異に基づく多発性嚢胞腎症発症機序の検証Principal InvestigatorOngoing
- Principal Investigator
  
  釘田雅則
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-
- Principal Investigator
  
  Nagao Shizuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University
Investigation of therapeutic effect of vitamin A on ciliopathy and promotion of its therapeutic effectPrincipal Investigator
- Principal Investigator
  
  KUGITA Masanori
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Fujita Health University
Study on the new cyst formation mechanism through the cell proliferation with the abnormal modification of RXR and examination of its mechanism-mediated suppressed effect on polycystic kidney diseasePrincipal Investigator
- Principal Investigator
  
  KUGITA Masanori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University
A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascade
- Principal Investigator
  
  SHIZUKO Nagao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] Annual Review 2013腎臓2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24790393
[Book] Annual Review 2013腎臓2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄　（分担）
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats2019
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Kazuhiro Nishii, Tamio Yamaguchi.
- Journal Title
  
  PLOS ONE
  
  Volume: 14(3)
- DOI
  10.1371/journal.pone.0207461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07076, KAKENHI-PROJECT-18K11141
[Journal Article] Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease2018
- Author(s)
  Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, Takeda N, Wake M, Honda K, Zhou J, Nangaku M
- Journal Title
  
  Mol Cell Biol.
  
  Volume: e-Pub
- DOI
  10.1128/mcb.00337-17
- NAID
  40021751803
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K08435, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
[Journal Article] Distinct oxylipin alterations in diverse models of cystic kidney diseases.2017
- Author(s)
  Md Monirujjamana, Jessay G. Devassy, Tamio Yamaguchi, Nikhil Sidhu, Masanori Kugita, Melissa Gabbs, Shizuko Nagao, Jing Zhou, Amir Ravandi, Harold M. Aukema.
- Journal Title
  
  Biochim Biophys Acta. -Molecular and Cell Biology of Lipids-
  
  Volume: 1862(12) Pages: 1562-1574
- DOI
  10.1016/j.bbalip.2017.08.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Journal Article] Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease.2017
- Author(s)
  Masanori Kugita, Kazuhiro Nishii, Tamio Yamaguchi, Atsushi Suzuki, Yukio Yuzawa, Shigeo Horie, Eiji Higashihara, Shizuko Nagao.
- Journal Title
  
  PLoS One.
  
  Volume: 12(5)
- DOI
  10.1371/journal.pone.0177934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08435
[Journal Article] 嚢胞性腎疾患モデル動物2015
- Author(s)
  長尾静子, 釘田雅則, 吉原大輔, 佐々木麻衣, 山口太美雄.
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: 1 Pages: 180-193
- Data Source
  KAKENHI-PROJECT-24790393
[Journal Article] ヒト多発性嚢胞腎症の動物モデル発生病態の解析2014
- Author(s)
  長尾静子, 長尾静子, 釘田雅則, 吉原大輔, 佐々木麻衣, 山口太美雄.
- Journal Title
  
  小児外科
  
  Volume: 46 Pages: 644-649
- Data Source
  KAKENHI-PROJECT-24790393
[Journal Article] Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.2013
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Horie S, Nakanishi K, Abe T, Aukema HA, Yamaguchi T, Nagao S
- Journal Title
  
  PLoS One
  
  Volume: 8(12)
- DOI
  10.1371/journal.pone.0081480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591580, KAKENHI-PROJECT-24790393
[Journal Article] 多発性嚢胞腎発症のメカニズム2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄
- Journal Title
  
  Annual Review 2013 腎臓 (冨野康日己、柏原直樹、成田一衛編、中外医学社、東京)
  
  Pages: 101-108
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in PPAR-γ agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease2012
- Author(s)
  Yoshihara D, Kugita M, Yamaguchi T, Aukema H.M., Kurahashi H., Morita M., Hiki Y., Calvet J.P., Wallace D.P., Toyohara T., TAbe T., Nagao S.
- Journal Title
  
  PPAR Research
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Animal models for human polycystic kidney disease2012
- Author(s)
  Nagao S, Kugita M, Yoshihara D, Yamaguchi T
- Journal Title
  
  Exp Anim.
  
  Volume: 61(5) Pages: 477-88
- NAID
  10031121852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Animal models for human polycystic kidney disease.2012
- Author(s)
  Shizuko Nagao, Kugita M, Yoshihara D, Yamaguchi T.
- Journal Title
  
  Experimental Animal
  
  Volume: Vol.61, No.5 Pages: 477-488
- NAID
  10031121852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Animal models for human polycystic kidney disease.2012
- Author(s)
  Nagao S, Kugita M, Yoshihara D, Yamaguchi T.
- Journal Title
  
  Experimental Animal
  
  Volume: Vol.61, No.5 Pages: 477-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790393
[Journal Article] Global gene expression profiling in PPAR-y agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease2012
- Author(s)
  Yoshihara D, Kugita M, Yamaguchi T, Aukema HM, Kurahashi H, Morita M, Hiki Y, Calvet JP, Wallace DP, Toyohara T, Abe T, Nagao S.
- Journal Title
  
  PPAR Research
  
  Volume: 2012 Pages: 695898-695898
- DOI
  10.1155/2012/695898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351, KAKENHI-PUBLICLY-23013019, KAKENHI-PROJECT-23659182, KAKENHI-PROJECT-24390085, KAKENHI-PROJECT-24790393
[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011
- Author(s)
  Kugita M, Nishii K, Morita M, Yoshihara D, Kowa-Sugiyama H, Yamada K, Yamaguchi T, Wallace DP, Calvet JP, Kurahashi H, Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011
- Author(s)
  Kugita M., Nishii K., Morita M., Yoshihara D., Kowa-Sugiyama H., Yamada K., Yamaguchi T., Wallace D.P., Calvet J.P., Kurahashi H., Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Yoshihara D, Kurahashi H, Morita M,Kugita M, Hiki Y, Aukema HM, Yamaguchi T, Calvet JP, Wallace DP, Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Yoshihara D., Kurahashi H., Morita M., Kugita M., Hiki Y., Aukema HM., Yamaguchi T., Calvet JP., Wallace DP., Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Polycystic kidney disease in Han : SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.2010
- Author(s)
  Nagao S, Morita M, Kugita M, Yoshihara D, Yamaguchi T, Kurahashi H, Calvet JP, Wallace DP.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Polycystic kidney disease in Han : SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.2010
- Author(s)
  Nagao S, Morita M, Kugita M, Yoshihara D, Yamaguchi T, Kurahashi H, Calvet JP, Wallace DP.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物PCKラットにおける嚢胞形成関連代謝産物の探索2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、長尾静子
- Organizer
  第90回東海実験動物研究会、名古屋、2019年6月29日、名古屋市立大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 種類の繊毛病モデル動物を用いた多発性嚢胞腎における代謝産物の網羅的解析2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 2種類の繊毛病モデル動物を用いた多発性嚢胞腎における代謝産物の網羅的解析2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] 常染色体劣性多発性嚢胞腎疾患（ARPKD）モデル動物における一次繊毛長と形態に治療が与える影響について2019
- Author(s)
  熊本海生航、齊藤成、大野伸彦、服部宣子、釘田雅則、吉村文、長尾静子
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Sox2/CD63-GFPトランスジェニックラットの腎病態について2019
- Author(s)
  吉村文、熊本海生航、釘田雅則、長尾静子
- Organizer
  第90回東海実験動物研究会、名古屋、2019年6月29日、名古屋市立大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 多発性嚢胞腎症モデル動物PCKラットにおける嚢胞形成関連代謝産物の探索2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、長尾静子
- Organizer
  第90回東海実験動物研究会
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] 常染色体劣性多発性嚢胞腎疾患(ARPKD)モデル動物の腎臓におけるG protein-coupled receptorの刺激が一次繊毛長と形態に与える影響について2019
- Author(s)
  熊本海生航、齊藤成、大野伸彦、服部宣子、釘田雅則、吉村文、長尾静子
- Organizer
  第90回東海実験動物研究会、名古屋、2019年6月29日、名古屋市立大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] NG2活性化による腎髄質ペリサイト機能温存とラットPCK多発性嚢胞腎モデルにみられる糸球体病変の軽減2019
- Author(s)
  熊本海生航、釘田雅則、吉村文、藤本清秀、千原良友、小島直人、東原英二、長尾静子、石橋道男
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 腎性尿崩症様病態を示す新規トランスジェニックラット2019
- Author(s)
  吉村文、熊本海生航、釘田雅則、長尾静子
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] エクソソームマーカーCD63-GFPを腎臓で発現するトランスジェニックラット2019
- Author(s)
  吉村文、熊本海生航、釘田雅則、大平圭悟、落谷孝広、長尾静子
- Organizer
  第6回日本細胞外小胞学会、東京、2019年10月24日～25日、国立がん研究センター研究所
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Development and implantation of novel morphometric 3D capsule device to constrain structural change of polycystic kidney: a feasibility study in a rat model.2019
- Author(s)
  Kyongtae T. Bae#, Kanako Kumamoto#, Aya Yoshimura#, Masanori Kugita, Shigeo Horie, Tamio Yamaguchi, Junu T. Bae, Shizuko Nagao (# equal author)
- Organizer
  Kidney week, 2019, Washington, DC, U.S.A., Nov 5-10.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] ネフロン癆モデル動物pcyマウスの多発性嚢胞腎における代謝産物の網羅的解析2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第66回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] Comparison study of calorie matched high fat and high sugar diets on renal injury with lysosomal dysfunction in pre-diabetic mice.2019
- Author(s)
  Aya Yoshimura#, Tamio Yamaguchi#, Masanori Kugita#, Kanako Kumamoto, Kazuya Shiogama, Naomichi Ogitsu, Toshihiro Miura, Misao Yoneda, Yoichi Nagamura, Shizuko Nagao (# equal author)
- Organizer
  Kidney week, 2019, Washington, DC, U.S.A., Nov 5-10.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] ネフロン癆モデル動物pcyマウスの多発性嚢胞腎における代謝産物の網羅的解析2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第66回日本実験動物学会総会、福岡、2019年5月15日～17日、福岡国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 糖尿病モデルマウスにおけるキヌレニン経路代謝物の腎組織イメージング質量分析2018
- Author(s)
  松下祥子、高橋和男、伊藤辰将、山本康子、藤垣英嗣、毛利彰宏、中嶋和紀、尾之内高慶、辰川英樹、釘田雅則、長尾静子、人見清隆、齋藤邦明、瀬藤光利、湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Glucose metabolic profiles in renal tissue of an orthologous PCK rat model of human PKD using metabolic and proteomic analyses.2018
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Tamio Yamaguchi, Kazuki Nakajima, Kazuo Takahashi, Yukio Yuzawa
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Glucose metabolic profiles in renal tissue of an orthologous PCK rat model of human PKD using metabolic and proteomic analyses.2018
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Tamio Yamaguchi, Kazuki Nakajima, Kazuo Takahashi, Yukio Yuzawa
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] 多発性嚢胞腎症モデルPCKラットの腎臓におけるメタボローム解析―グルコース代謝経路についてー2018
- Author(s)
  釘田雅則、熊本海生航、吉村　文、山口太美雄、長尾静子
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Role of Retinoid X receptor pathway in cystogenesis with therapeutic potential in polycystic kidney disease.2018
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Harold M Aukema, Kazuhiro Nishii and Shizuko Nagao
- Organizer
  ISN Frontiers Meetings 2018, Tokyo, JAPAN, 2018 Feb 22-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 糖脂質合成酵素阻害剤はグルコース代謝を介してADPKDの病態を抑制する2018
- Author(s)
  中嶋和紀、石橋洋平、釘田雅則、中尾静羽、高橋和男、永松正、長尾静子、湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Renal and serum oxylipin alterations in the jck mouse, an orthologous model of human nephronophthisis.2018
- Author(s)
  Tamio Yamaguchi, Md Monirujjaman, Jessay G. Devassy, Melissa Gabbs, Nikhil Sidhu, Arumi Jha, Andrew J. Halayko, Masanori Kugita, Shizuko Nagao, Amir Ravandi, Harold M. Aukema
- Organizer
  ISN Frontiers Meetings 2018, Tokyo, JAPAN, 2018 Feb 22-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物PCKラットの腎臓における代謝産物解析－中心炭素代謝経路について－2018
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 多発性嚢胞腎症モデル動物PCKラットの腎臓における代謝産物解析～中心炭素代謝経路について～2018
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] Mitochondrial Morphological Abnormality in Cyst Epithelial Cells of Autosomal Dominant Polycystic Kidney Disease Patients.2018
- Author(s)
  Yu Ishimoto, Akira Shimizu, Masanori Kugita, Shizuko Nagao, Kenjiro Honda, Reiko Inagi, Masanomi Nangaku, Saori Nishio, Haruna Kawano, Shigeo Horie, Tomoko Kasahara, Kenji Osafune, Junichi Hoshino, Yoshifumi Ubara
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 嚢胞性腎疾患モデルラットの腎臓における嚢胞形成と一次繊毛長の関係2018
- Author(s)
  熊本海生航、吉村文、釘田雅則、長尾静子
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] 多発性嚢胞腎症モデルPCKラットの腎臓におけるメタボローム解析―グルコース代謝経路についてー2018
- Author(s)
  釘田雅則、熊本海生航、吉村　文、山口太美雄、長尾静子
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] Mitochondrial Morphological Abnormality in Cyst Epithelial Cells of Autosomal Dominant Polycystic Kidney Disease Patients.2018
- Author(s)
  Yu Ishimoto, Akira Shimizu, Masanori Kugita, Shizuko Nagao, Kenjiro Honda, Reiko Inagi, Masanomi Nangaku, Saori Nishio, Haruna Kawano, Shigeo Horie, Tomoko Kasahara, Kenji Osafune, Junichi Hoshino, Yoshifumi Ubara
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11141
[Presentation] Kidney Glycosphingolipidomics and Metabolomics Reveal Metabolic Crosstalk between Elevated Glycosphingolipids and Glucose Metabolisms in PKD Progression.2017
- Author(s)
  Kazuki Nakajima, Kazuo Takahashi, Masanori Kugita, Shizuko Nagao, Yukio Yuzawa
- Organizer
  Kidney week 2017, LA, U.S.A., 2017 Oct 31-Nov 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Suppressive Effect of RXR Ligand and MEK Inhibitor on RXR Expression and Cellular Proliferation in Immortalized Polycystic Kidney Cells.2017
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Kazuhiro Nishii, Mai Sasaki, Noboru Ogiso, Harold M. Aukema, Shizuko Nagao
- Organizer
  Kidney week 2017, New Orleans, LA, U.S.A., 2017 Oct 31-Nov 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Altered Liver Bioactive Lipid (Oxylipin) Profiles in PCK Rats with Polycystic Kidney and Liver Disease.2017
- Author(s)
  Tamio Yamaguchi, Jessay G. Devassy, Aruni Jha, Andrew J Halayko, Masanori Kugita, Shizuko Nagao, Amir Ravandi, Harold M Aukema
- Organizer
  Kidney week 2017, New Orleans, LA, U.S.A., 2017 Oct 31-Nov 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるRXRの発現と局在2016
- Author(s)
  吉原大輔、釘田雅則、長尾静子
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] Increased salt intakes dose not deteriorate renal cystic disease progression in high water loaded PCK rats.2016
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Yoichi Nagamura, Harold M Aukema, Shizuko Nagao
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるレチノイドX受容体の解析2016
- Author(s)
  釘田雅則、吉原大輔、加藤由布、小木曽　昇、下村恭代、西田修、長尾静子
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  川崎
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるレチノイドX受容体の解析2016
- Author(s)
  釘田雅則、吉原大輔、加藤由布、小木曽昇、下村恭代、西田修、長尾静子
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  神奈川県、川崎　　ミューザ川崎シンフォニーホール
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 血中アミロイドβ蛋白(Aβ)除去によるアルツハイマー病治療システム；ラット血中Aβ除去による血液・髄液中Aβの変化2016
- Author(s)
  川口和紀、木野村淳、平林晃知、渡辺康太、青木洋樹、榊原由莉、坂田美和、釘田雅則、加藤政雄、長尾静子、北口暢哉
- Organizer
  第6回日本認知症予防学会学術集会
- Place of Presentation
  宮城県、仙台　東北大学百周年記念会館川内萩ホール
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Increased salt intakes dose not deteriorate renal cystic disease progression in high water loaded PCK rats.2016
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Yoichi Nagamura, Harold M Aukema, Shizuko Nagao.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] ミトコンドリア機能異常は多発性嚢胞腎の嚢胞形成に関与する2016
- Author(s)
  石本遊、南学正臣、吉原大輔、釘田雅則、長尾静子
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  神奈川県、横浜　パシフィコ横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるRXRの発現と局在2016
- Author(s)
  吉原大輔、釘田雅則、長尾静子
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] Mitochondrial dysfunction contributes to cysts proliferation of autosomal dominant polycystic kidney disease.2016
- Author(s)
  Yu Ishimoto, Masaomi Nangaku, Masanori Kugita, Shizuko Nagao, Akira Shimizu, Jing Zhou, Reiko Inagi.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Mitochondrial dysfunction contributes to cyst proliferation of autosomal dominant polycystic kidney disease.2016
- Author(s)
  Yu Ishimoto, Masaomi Nangaku, Shizuko Nagao, Daisuke Yoshihara, Masanori Kugita, Yoko Yoshida, Jing Zhou, Mike Murphy, Akira Shimizu, Reiko Inagi.
- Organizer
  The Asian Pacific Society of Nephrology
- Place of Presentation
  Perth, WA, Australia
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるレチノイドX受容体の解析2016
- Author(s)
  釘田雅則、吉原大輔、加藤由布、小木曽昇、下村恭代、西田修、長尾静子
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  川崎、ミューザ川崎シンフォニー
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるRXRの発現と局在2016
- Author(s)
  吉原大輔、釘田雅則、長尾静子
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  神奈川県、横浜　パシフィコ横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Bioactive Lipid Alterations in the jck and pcy mouse models of nephronophthisis.2016
- Author(s)
  Tamio Yamaguchi, Nikhil Sidhu, Jessay Gopuran Devassy, Melissa Gabbs, Amir Ravandi, Masanori Kugita, Shizuko Nagao, Harold M. Aukema.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Beneficial effect of combined treatment of two somatostatin analogs in an orthologous model of human autosomal recessive polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nishii K, Suzuki A, Higashihara E, Horie S, Yamaguchi T, Nagao S.
- Organizer
  1th ASPR Congress & the 118th Annual Meeting of the Japan Pediatric Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-04-15
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Expression and distribution of retinoid X receptor in rodent models of polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nagao S.
- Organizer
  11th ASPR Congress & the 118th Annual Meeting of the Japan Pediatric Society
- Place of Presentation
  Osaka
- Year and Date
  2015-04-15
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] Retinoid X receptor pathway, a novel signaling cascade responsible for cystogenesis in three rodent models of polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Aukema HM, Yamaguchi T, Nagao S.
- Organizer
  American Society of Nephrology Kidney Week 2015
- Place of Presentation
  San Diego, CA, U.S.A.
- Year and Date
  2015-11-03
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症のモデル動物であるPCKラットにおけるGi作動薬の病態進行抑制効果2015
- Author(s)
  釘田雅則、吉原大輔、西井一宏、鈴木敦詞、湯澤由紀夫、山口太美雄、堀江重郎、東原英二、長尾静子
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 嚢胞性腎疾患モデル動物における有用性の比較2015
- Author(s)
  釘田雅則、吉原大輔、田代遥、加藤雅也、長尾静子
- Organizer
  第87回東海実験動物研究会
- Place of Presentation
  岐阜
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] であるPCKラットにおけるGi作動薬の病態進行2015
- Author(s)
  吉原大輔、釘田雅則、西井一宏、鈴木敦詞、湯澤由紀夫、東原英二、堀江重郎、山口太美雄、長尾静子
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Retinoid X receptor pathway, a novel signaling cascade responsible for cystogenesis in three rodent models of polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Aukema HM, Yamaguchi T, Nagao S.
- Organizer
  American Society of Nephrology Kidney Week 2015
- Place of Presentation
  San Diego, CA, U.S.A.
- Year and Date
  2015-11-03
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] Expression and distribution of retinoid X receptor in rodent models of polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nagao S.
- Organizer
  11th ASPR Congress & the 118th Annual Meeting of the Japan Pediatric Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-04-15
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 核内受容体を介した情報伝達経路の解析2015
- Author(s)
  釘田雅則、吉原大輔、長尾静子
- Organizer
  第1回シーズ・ニーズ発表交流会
- Place of Presentation
  豊明
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K16222
[Presentation] 多発性嚢胞腎症モデル動物Cyラットの腎臓におけるRXRの解析2014
- Author(s)
  釘田雅則、佐々木麻衣、吉原大輔、長尾静子
- Organizer
  日本実験動物科学技術さっぽろ 2014 第61回日本実験動物学会総会第48回日本実験動物技術者総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞腎の動物モデル2013
- Author(s)
  長尾静子 (枝澄香)、釘田雅則、吉原大輔、山口多美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD)2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD)2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果2013
- Author(s)
  長尾静子(枝澄香)、吉原大輔、釘田雅則、佐々木麻衣、堀江重郎、中西浩一、阿部高明、山口太美雄
- Organizer
  第48回日本小児腎臓学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果2013
- Author(s)
  長尾静子、吉原大輔、釘田雅則、佐々木麻衣、堀江重郎、中西浩一、阿部高明、山口太美雄
- Organizer
  第48回日本小児腎臓学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞腎の動物モデル.2013
- Author(s)
  長尾静子(枝澄香)、釘田雅則、吉原大輔、山口太美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症における核内受容体Retinoid X Receptorの発現増加と細胞内局在の変化2013
- Author(s)
  佐々木麻衣、釘田雅則、吉原大輔、長尾静子
- Organizer
  第8回日本臨床検査学教育学会学術大会
- Place of Presentation
  大坂
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] ヒト多発性嚢胞腎症モデル動物の有用性と必要性2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 適切な疾患モデル動物に関する考察 ―多発性嚢胞腎症モデル動物を例としてー2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、佐々木麻衣
- Organizer
  第83回東海実験動物研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞腎の動物モデル2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞性腎疾患における適切なモデル動物の選定2013
- Author(s)
  吉原大輔、釘田雅則、佐々木麻衣、長尾静子
- Organizer
  第45回藤田学園医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞腎症におけるRetinoid X Receptorを介した新規嚢胞形成機序の解明2013
- Author(s)
  佐々木麻衣、釘田雅則、吉原大輔、長尾静子
- Organizer
  第45回藤田学園医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD).2013
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Horie S, Nakanishi K, Abe T, Aukema HM, Yamaguchi T, Nagao S.
- Organizer
  World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果2013
- Author(s)
  長尾静子、吉原大輔、釘田雅則、佐々木麻衣、堀江重郎、中西浩一、阿部高明、山口太美雄
- Organizer
  第48回日本小児腎臓病学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD).2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology2013
- Place of Presentation
  HongKong, China
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ラット多発性嚢胞腎における PPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング.2012
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾静子(枝澄香)
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓における retinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾静子(枝澄香)
- Organizer
  日本実験動物科学・技術九州 2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model of human ARPKD2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara, Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットPCKにおけるテルミサルタンの病態発現抑制効果2012
- Author(s)
  吉原大輔, 釘田雅則, 山口太美雄, 長尾静子
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model of human ARPKD.2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara, Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model ofhuman ARPKD.2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara,Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患におけるPPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔, 釘田雅則, 山口太美雄, 長尾静子
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human ARPKD.2012
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Shigeo Horie, Tamio Yamaguchi, Harold M. Aukema, Shizuko Nagao.
- Organizer
  American Society of Nephrology Kidney week 2012
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] ラット多発性嚢胞腎におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2012
- Author(s)
  吉原大輔, 釘田雅則, 倉橋浩樹, 森田美和, 比企能之, 山口太美雄, 豊原敬文, 阿部高明, 長尾静子
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞腎ラットPCKにおけるテルミサルタンの病態発現抑制効果2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子 (枝澄香)
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるretinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則, 吉原大輔, 山口太美雄, 長尾静子
- Organizer
  日本実験動物科学・技術九州2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human ARPKD2012
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Shigeo Horie, Harold M. Aukema,Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  American Society of Nephrology Kidney Week 2012
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ラット多発性嚢胞腎におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2012
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾静子 (枝澄香)
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるretinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾静子 (枝澄香)
- Organizer
  日本実験動物科学・技術九州2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患におけるPPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔, 釘田雅則, 山口太美雄, 長尾静子 (枝澄香)
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患における PPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子(枝澄香)
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラット PCKにおけるテルミサルタンの病態発現抑制効果.2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子(枝澄香)
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 網羅的遺伝子発現解析を用いた多発性嚢胞腎ラットPCKにおけるPPARγアゴニストによる治療機序の検証2011
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾枝澄香(静子)
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PPAE-γ agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Daisuke Yoshihara., Hiroki Kurahashi., Miwa Morita., Masanori Kugita., Yoshiyuki Hiki., Harold M.Aukema., Tamio Yamaguchi., James P.Calvet, Darren P.Wallace., Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Global gene expression profiling in kidneys of PPAR-γ agonist-treated PCK rats, an orthologous model of human ARPKD.2011
- Author(s)
  Yoshihara D, Kugita M, Kurahashi H, Morita M, Hiki Y, Yamaguchi T, Aukema HM, Wallace DP, Calvet JP, Toyohara T, Abe T, Nagao S.
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition 2011
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 羅的遺伝子発現解析を用いた多発性嚢胞腎ラット PCK における PPAR-γアゴニストによる治療機序の検証2011
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾枝澄香(静子)
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラット PCK の腎臓における PPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2011
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、倉橋浩樹、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] RXR は嚢胞形成機序における共通の因子か?2011
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] RXRは嚢胞形成機序における共通の因子か?2011
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Global gene expression profiling in kidneys of PPAR-gamma agonist-treated PCK rats, an orthologous model of human ARPKD2011
- Author(s)
  Yoshihara D., Kugita M., Kurahashi H, Morita M, Hiki Y, Yamaguchi T, Aukema HM, Wallace DP, Calvet JP, Toyohara T., Abe T., Nagao S.
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Wallace Darren 多発性嚢胞腎症モデルであるj ckマウスの特徴.2011
- Author(s)
  長尾枝澄香(静子)、吉原大輔、釘田雅則、森田美和、山口太美雄
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットPCKの腎臓におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2011
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、倉橋浩樹、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト多発性嚢胞腎症のラットモデルにおけるPPAE-γアゴニストの治療効果2011
- Author(s)
  吉原大輔、倉橋浩樹、森田美和、釘田雅則、比企能之、Aukema Harold、山口太美雄、Calvet James、Wallace Darren、長尾枝澄香(静子)
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデルであるjckマウスの特徴2011
- Author(s)
  長尾枝澄香(静子)、吉原大輔、釘田雅則、森田美和、山口太美雄、Wallace Darren
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト多発性嚢胞腎症のラットモデルにおける PPAR-γアゴニストの治療効果2011
- Author(s)
  吉原大輔、倉橋浩樹、森田美和、釘田雅則、比企能之、Aukema Harold、山口太美雄、Calvet James、Wallace Darren、長尾枝澄香(静子)
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 嚢胞性腎臓疾患モデル Cy ラットにおける嚢胞形成と RXR との関連性についての検討.2010
- Author(s)
  釘田雅則、西井一宏、森田美和、吉原大輔、山口太美雄、日下守、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PCK ラットの腎臓と肝臓における PPAR-γアゴニストの治療効果2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第18回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 非侵襲的拒絶反応診断法としてのFDG-PETの有用性の検討2010
- Author(s)
  森田美和、辻厚至、釘田雅則、吉原大輔、李小康、杉岡篤, 長尾静子
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PCKラットの腎臓と肝臓におけるPPAR-γアゴニストの治療効果2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第18回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 嚢胞性腎臓疾患モデルCyラットにおける嚢胞形成とRXRとの関連性についての検討2010
- Author(s)
  釘田雅則、西井一宏、森田美和、吉原大輔、山口太美雄、日下守、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒトARPKDとオーソログな遺伝子変異モデルであるPCKラットの腎・肝組織における情報伝達系の検討2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、倉橋浩樹、山口太美雄、長尾静子
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Thiazolidinedione Ameliorates Autosomal Recessive Polycystic Kidney and Liver Disease in the PCK Rat, an Orthologous Model of Human ARPKD.2010
- Author(s)
  Yoshihara D, Kurahashi H, Morita M, Kugita M, Hiki Y, Aukema HM, Yamaguchi T, Calvet JP, Wallace DP, Nagao S.
- Organizer
  American Society of Nephrology 43rd Annual Meeting & Scientific Exposition.
- Place of Presentation
  Denver, CO USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 非侵襲的拒絶反応診断法としての FDG-PET の有用性の検討.2010
- Author(s)
  森田美和、辻厚至、釘田雅則、吉原大輔、李小康、杉岡篤, 長尾静子
- Organizer
  第57回日本実験動物学会総会.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットモデルPCKの腎臓と肝臓における細胞情報伝達系の解析2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Thiazolidinedione Ameliorates Autosomal Recessive Polycystic Kidney and Liver Disease in the PCK Rat, an Orthologous Model of Human ARPKD.2010
- Author(s)
  Yoshihara D., Kurahashi H., Morita M., Kugita M., Hiki Y., Aukema H.M., Yamaguchi T., Calvet J.P., Wallace D.P., Nagao S.
- Organizer
  American Society of Nephrology 43rd Annual Meeting & Scientific Exposition
- Place of Presentation
  Denver, CO USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットモデル PCK の腎臓と肝臓における細胞情報伝達系の解析.2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト ARPKDとオーソログな遺伝子変異モデルである PCK ラットの腎・肝組織における情報伝達系の検討.2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、倉橋浩樹、山口太美雄、長尾静子
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Beneficial effect of combined treatment of two Gi protein activators in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease.
- Author(s)
  Kugita M, Yoshihara D, Sasaki M, Nishii K, Suzuki A, Higashihara E, Horie S, Yamaguchi T, Nagao S.
- Organizer
  American Society of Nephrology Kidney Week 2014
- Place of Presentation
  Philadelphia
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Expression and distribution of retinoid X receptor in the kidney from four kinds of rodent models for polycystic kidney disease.
- Author(s)
  Masanori Kugita, Mai Sasaki, Daisuke Yoshihara, Shizuko Nagao
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Expression and distribution of retinoid X receptor in rodent models of polycystic kidney disease.
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nagao S.
- Organizer
  The 11th Asian Society for Pediatric Research 2015
- Place of Presentation
  OSAKA
- Year and Date
  2015-04-15 – 2015-04-18
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 多発性嚢胞腎症におけるRetinoid X Receptorを介した病態進行機序解析と治療への応用
- Author(s)
  佐々木麻衣、釘田雅則、倉内靖代、和田裕司、吉原大輔、長尾静子
- Organizer
  第46回藤田医学会総会
- Place of Presentation
  豊明
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] 発性嚢胞腎症モデル動物Cyラットの腎臓におけるRXRの解析
- Author(s)
  釘田雅則、佐々木麻衣、吉原大輔、長尾静子
- Organizer
  日本実験動物科学技術さっぽろ2014第61回日本実験動物学会総会第48回日本実験動物技術者協会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] ペルオキシソーム増殖因子活性化受容体(PPARγ)情報伝達経路は多発性嚢胞腎症の病態進行を制御する
- Author(s)
  吉原大輔、釘田雅則、長尾静子
- Organizer
  第46回藤田医学会総会
- Place of Presentation
  豊明
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-24790393
[Presentation] Beneficial effect of combined treatment of two somatostatin analogs in an orthologous model of human autosomal recessive polycystic kidney disease.
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nishii K, Suzuki A, Higashihara E, Horie S, Yamaguchi T, Nagao S.
- Organizer
  The 11th Asian Society for Pediatric Research 2015
- Place of Presentation
  OSAKA
- Year and Date
  2015-04-15 – 2015-04-18
- Data Source
  KAKENHI-PROJECT-24790393

1. SHIZUKO Nagao (20183527)

# of Collaborated Projects: 3 results

# of Collaborated Products: 92 results
2. YOSHIHARA Daisuke (70454402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 63 results
3. YAMAGUCHI Tamio (70536292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 56 results
4. KURAHASHI Hiroki (30243215)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
5. MORITA Miwa (90329699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
6. YAGYU Shigeru (10200479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIKI Yoshiyuki (20156566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
8. Yuzawa Yukio (00191479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. Suzuki Atsushi (90340265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. Saito Kuniaki (80262765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 熊本海生航 (10469322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 吉村文 (90466483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
13. NAKANISHI Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. KUMAMOTO Kanako

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
15. NANGAKU Masaomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. ISHIMOTO Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 武田憲彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 稲城玲子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kugita Masanori 釘田 雅則

MASANORI Kugita 釘田 雅則

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Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.Ongoing

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食事性刺激に起因するDNA変異に基づく多発性嚢胞腎症発症機序の検証Principal InvestigatorOngoing

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Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-

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Investigation of therapeutic effect of vitamin A on ciliopathy and promotion of its therapeutic effectPrincipal Investigator

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Study on the new cyst formation mechanism through the cell proliferation with the abnormal modification of RXR and examination of its mechanism-mediated suppressed effect on polycystic kidney diseasePrincipal Investigator

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A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascade

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[Book] Annual Review 2013腎臓2013

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[Book] Annual Review 2013腎臓2013

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[Journal Article] Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats2019

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[Journal Article] Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease2018

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NAID

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[Journal Article] Distinct oxylipin alterations in diverse models of cystic kidney diseases.2017

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[Journal Article] Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease.2017

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[Journal Article] 嚢胞性腎疾患モデル動物2015

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[Journal Article] ヒト多発性嚢胞腎症の動物モデル発生病態の解析2014

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[Journal Article] Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.2013

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Kugita Masanori 釘田雅則

MASANORI Kugita 釘田雅則