Yamamoto Yasuko 山本康子

… Alternative Names

YAMAMOTO Yasuko 山本康子

山本康子ヤマモトヤスコ

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Researcher Number	00331869
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 保健学研究科, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 藤田医科大学, 保健学研究科, 准教授 2016 – 2017: 藤田保健衛生大学, 医療科学部, 准教授 2015: 藤田保健衛生大学, 保健学研究科, 准教授 2011 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2012 – 2013: 京都大学, 大学院・医学研究科, 助教 … More 2008 – 2011: 京都大学, 医学研究科, 助教 2004 – 2005: 香川県立保健医療大学, 保健医療学部・臨床検査学科, 助手 2004: 香川県立保健医療大学, 保健医療学部, 助手 2001: 香川県立医療短期大学, 臨床検査学科, 助手 2000: 香川県立医療短期大学, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related / Experimental pathology Except Principal Investigator Laboratory medicine / Biological Sciences / Basic Section 53040:Nephrology-related / Basic Section 49030:Experimental pathology-related / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach … More / Basic Section 49010:Pathological biochemistry-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 37030:Chemical biology-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Psychiatric science / Applied health science / Applied health science Less
Keywords	Principal Investigator トリプトファン代謝 / IDO2 / インドールアミン酸素添加酵素2 / 炎症慢性化機構 / 糖尿病 / 脂質代謝 / インドールアミン酸素添加酵素２ / インシュリン抵抗性 / 生活習慣病 / トリプトファン代謝酵素 … More / 免疫機能 / 免疫調節因子 / 炎症 / 細胞増殖 / 腫瘍 / 腫瘍免疫 / 薬効予測 / 自己免疫性疾患 / IDO1 / 薬効予測システム / 関節リウマチ / indoleamine 2,3-dioxygenase 1 / rheumatoid arthritis / 酵素GPI-PLD / GPI-PLD / 癌胎児性抗原 … More Except Principal Investigator トリプトファン代謝 / バイオマーカー / アミノ酸代謝 / 先制医療 / ストレス / うつ病 / 抑うつ / トリプトファン / サイトカイン / CEA / インテグリン / 増殖因子 / キヌレニナーゼ / 乾癬 / 新規診断法 / 診断薬と診断法の研究・開発 / 液性免疫 / SARS-CoV-2 / Drug Delivery System / DDS型薬剤 / グローバル展開 / First-in-Class / アンメッド・メディカル・ニーズ / ペプチド創薬 / DDS / ヒト型抗体 / ペプチド医薬品 / 時系列データベース / 生活習慣病予測モデル / 暦年的データベース / 機械学習 / 生活習慣病 / 芳香族炭化水素受容体 / キヌレン酸 / キヌレニン / 多発性嚢胞腎症 / 白血球 / 免疫複合体 / 半月体形成 / 抗GBM抗体型腎炎 / 好中球 / マクロファージ / 遺伝子欠損マウス / 糸球体腎炎 / 腎障害 / 副作用 / シスプラチン / 出生時体重 / 周産期栄養状態 / 周産期うつ / 産後うつ病 / 周産期うつ病 / MAGE-D1 / 診断バイオマーカー / 精神薬理学 / うつ様症状 / 疼痛性障害 / ユビキチン化セロトニントランスポーター / ユビキチン化 / セロトニントランスポーター / 診断 / うつ / メタボローム / ビックデータ / ビッグデータ解析 / トリプトファン代謝産物 / Osteoarthritis;OA / Rheumatoid arthritis;RA / Progranulin;PGRN / 関節リウマチ / プログラニュリン / 心身の健康 / インターネット / 健康科学 / 酵素誘導 / 病態検査学 / コンパニオン診断 / ウイルス性肝炎 / IDO / インターフェロン / 臨床化学 / 炎症・免疫 / 生理活性物質 / 臨床検査医学 / ラミニン / 脳転移 / アンギオポエチン / 血管新生因子 / HB-EGF / erb-B / 癌の転移 / VEGF / カドヘリン / 接着分子 Less

乾癬におけるトリプトファン代謝に着目した病態解明と制御法の開発
- Principal Investigator
  
  齋藤邦明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
Indoleamine 2’3-dioxygenase 2が関与する炎症慢性化機構の解明Principal Investigator
- Principal Investigator
  
  山本康子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
多角的なSARS-CoV-2免疫獲得状況の調査研究
- Principal Investigator
  
  藤垣英嗣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Fujita Health University
Research and development of diagnostic methods focusing on novel molecules and exosomes that are strongly expressed specifically for endometriosis.
- Principal Investigator
  
  杉原一廣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Fujita Health University
Roles of tryptophan metabolism-related enzymes and those metabolites in antibody-mediated glomerulonephritis
- Principal Investigator
  
  坪井直毅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
キヌレニン／キヌレン酸を標的とした多発性嚢胞腎症における新規治療薬の開発
- Principal Investigator
  
  釘田雅則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
時系列データベースを活用した生活習慣病予測モデルの構築および検証
- Principal Investigator
  
  齋藤邦明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
Development of novel cancer treatment strategies to reduce the side effects of cisplatin
- Principal Investigator
  
  Fujigaki Hidetsugu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Fujita Health University
Deficiency of indoleamine 2,3-dioxygenase 2 is associated with the development of lifestyle-related diseases.Principal Investigator
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
DDS type peptide drug discovery and diagnostics development research which makes the target malignant tumor-specific molecules.
- Principal Investigator
  
  SUGIHARA KAZUHIRO
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Fujita Health University
Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Fujita Health University
Development of the next-generation diagnosis method for depression by using byomakers based on pathophysiological mechanism
- Principal Investigator
  
  Nabeshima Toshitaka
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Fujita Health University
Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through regulation of IL-6/stat3 signallingPrincipal Investigator
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
Tryptophan metabolic profile is effective for preemptive medicine in depression symptoms
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Fujita Health University
Antitumor efficacies of indoleamine 2,3-dioxygenase 2 in lewis lung carcinoma mice model.Principal Investigator
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Kyoto University
Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Kyoto University
Increases in Tryptophan-kynurenine pathway metabolism following interferon-induced depression
- Principal Investigator
  
  SAITO KUNIAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Studies on thescale for stress induced emotional changes
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Kyoto University
Novel validation system for biologicaI drug efficacy in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Yasuko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
The pathophysiologic role of indoleamine 2, 3-dioxygenase in viral infectious diseases
- Principal Investigator
  
  SAITOU Kuniaki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
癌胎児性抗原(CEA)の分泌における酵素GPI-PLDの意義Principal Investigator
- Principal Investigator
  
  山本康子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kagawa Prefectural College of Health Sciences
癌の転移における接着分子インテグリンの意義
- Principal Investigator
  
  松浦成昭
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
接着分子、増殖因子発現による癌転移の予測診断
- Principal Investigator
  
  松浦成昭
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
癌の転移予測診断における接着分子、増殖因子の意義
- Principal Investigator
  
  松浦成昭
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University

[Book] :Tumor Necrosis factor2014
- Author(s)
  Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K.
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-23390149
[Book] Tumor Necrosis factor
- Author(s)
  Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Cohort profile: rationale and design of the Resource Center for Health Science (RECHS) project ? a study of health hazards and medical cost burden among the Japanese population2024
- Author(s)
  Morishita Tetsuji、Takemura Masao、Hayashi Makoto、Saito Kuniaki、Yamamoto Yasuko、Tsurumi Hisashi、Matsunami Hidetoshi
- Journal Title
  
  BMJ Open
  
  Volume: 14 Issue: 2 Pages: e077720-e077720
- DOI
  10.1136/bmjopen-2023-077720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11891
[Journal Article] Identification of 2′,4′,6′-Trihydroxyacetophenone as Promising Cysteine Conjugate Beta-Lyase Inhibitor for Preventing Cisplatin-Induced Nephrotoxicity2023
- Author(s)
  Sukeda Nao、Fujigaki Hidetsugu、Ando Tatsuya、Ando Honomi、Yamamoto Yasuko、Saito Kuniaki
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 22 Issue: 7 Pages: 873-881
- DOI
  10.1158/1535-7163.mct-22-0564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05757
[Journal Article] Dataset dependency of low-density lipoprotein-cholesterol estimation by machine learning2023
- Author(s)
  Hidekazu Ishida、Nagasawa Hiroki、Yamamoto Yasuko、Doi Hiroki、Saito Midori、Ishihara Yuya、Fujita Takashi、Ishida Mariko、Kato Yohei、Kikuchi Ryosuke、Matsunami Hidetoshi、Takemura Masao、Ito Hiroyasu、Saito Kuniaki
- Journal Title
  
  Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
  
  Volume: 60 Issue: 6 Pages: 396-405
- DOI
  10.1177/00045632231180408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11891
[Journal Article] Establishment of Model Mice to Evaluate Low Niacin Nutritional Status2023
- Author(s)
  MIZUTANI Amane、SATO Miu、FUJIGAKI Hidetsugu、YAMAMOTO Yasuko、SAITO Kuniaki、HATAYAMA Sho、FUKUWATARI Tsutomu
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 69 Issue: 5 Pages: 305-313
- DOI
  10.3177/jnsv.69.305
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2023-10-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16800, KAKENHI-PROJECT-22K11891
[Journal Article] Validation of the Martin method to estimate low-density lipoprotein cholesterol concentrations in Japanese populations and a modified method for laboratory information system application.2022
- Author(s)
  Ishida H, Yamamoto Y, Saito M, Ishihara Y, Fujita T, Ishida M, Kato Y, Nohisa Y, Matsunami H, Takemura M, Hata T, Ito H, Saito K.
- Journal Title
  
  Ann Clin Biochem.
  
  Volume: 59(5) Issue: 5 Pages: 316-323
- DOI
  10.1177/00045632221098870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-18K02505
[Journal Article] The Trajectory of the COVID-19 Vaccine Antibody Titers Over Time and the Association of Mycophenolate Mofetil in Solid Organ Transplant Recipients.2022
- Author(s)
  Sakai A, Morishita T, Suzumura K, Hanatate F, Yoshikawa T, Sasaki N, Lee S, Fujita K, Hara T, Araki H, Tagami A, Murayama M, Yamada R, Iwata A, Sobajima T,Kasahara Y, Matsuzawa Y, Takemura M, Yamamoto Y, Fujigaki H, Saito K, Tsurumi H,　Matsunami H.
- Journal Title
  
  Transplant Proc.
  
  Volume: 54(10) Issue: 10 Pages: 2638-2645
- DOI
  10.1016/j.transproceed.2022.10.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11891
[Journal Article] CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma2022
- Author(s)
  Okamoto Akinao、Fujigaki Hidetsugu、Iriyama Chisako、Goto Naoe、Yamamoto Hideyuki、Mihara Keichiro、Inaguma Yoko、Miura Yasuo、Furukawa Katsuya、Yamamoto Yukiya、Akatsuka Yoshiki、Kasahara Senji、Miyao Kotaro、Kajiya Ryoko、Okamoto Masataka、Saito Kuniaki、Tomita Akihiro
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 11 Pages: 3230-3233
- DOI
  10.1182/bloodadvances.2021006302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-23K24297
[Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid2021
- Author(s)
  Mori Yuko、Mouri Akihiro、Kunisawa Kazuo、Hirakawa Mami、Kubota Hisayoshi、Kosuge Aika、Niijima Moe、Hasegawa Masaya、Kurahashi Hitomi、Murakami Reiko、Hoshi Masato、Nakano Takashi、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 405 Pages: 113191-113191
- DOI
  10.1016/j.bbr.2021.113191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
[Journal Article] Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress2021
- Author(s)
  Kosuge Aika、Kunisawa Kazuo、Arai Satoshi、Sugawara Yumika、Shinohara Katsuki、Iida Tsubasa、Wulaer Bolati、Kawai Tomoki、Fujigaki Hidetsugu、Yamamoto Yasuko、Saito Kuniaki、Nabeshima Toshitaka、Mouri Akihiro
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 96 Pages: 200-211
- DOI
  10.1016/j.bbi.2021.05.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
[Journal Article] Serum GP88 as a predictive biomarker for hepatocellular carcinoma in patients with viral hepatitis C after direct-acting antiviral agents.2021
- Author(s)
  Hidekazu Ishida, Masao Takemura, Atsushi Suetsugu, Takafumi Naiki, Takuji Tanaka, Tomita Eiichi, Ginette Serrero, Hidetoshi Matsunami, Yasuko Yamamoto, Kuniaki Saito.
- Journal Title
  
  Annals of Clinical Biochemistry.
  
  Volume: 11 Issue: 6 Pages: 605-613
- DOI
  10.1177/00045632211036723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490
[Journal Article] Progranulin depletion inhibits proliferation via the transforming growth factor beta/SMAD family member 2 signaling axis in Kasumi-1 cells2021
- Author(s)
  Yabe Kuniaki、Yamamoto Yasuko、Takemura Masao、Hara Takeshi、Tsurumi Hisashi、Serrero Ginette、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Heliyon
  
  Volume: 7 Issue: 1 Pages: e05849-e05849
- DOI
  10.1016/j.heliyon.2020.e05849
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761
[Journal Article] Serum Profiles of Tryptophan-Kynurenine Pathway Metabolites in Psoriasis.2021
- Author(s)
  Mariko Seishima, Yasuko Yamamoto, Masashi Sakurai, Rika Sakai, Kento Fujii, Yoko Mizutani, Kuniaki Saito.
- Journal Title
  
  Explor Immunol.
  
  Volume: 1 Pages: 258-268
- DOI
  10.37349/ei.2021.00017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-19K08788
[Journal Article] Prefrontal cortex miR‐874‐3p prevents lipopolysaccharide‐induced depression‐like behavior through inhibition of indoleamine 2,3‐dioxygenase 1 expression in mice2020
- Author(s)
  Suento Willy Jaya、Kunisawa Kazuo、Wulaer Bolati、Kosuge Aika、Iida Tsubasa、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Tanra Andi Jayalangkara、Saito Kuniaki、Mouri Akihiro、Nabeshima Toshitaka
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: - Issue: 6 Pages: 1963-1978
- DOI
  10.1111/jnc.15222
- NAID
  130008001606
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K16679
[Journal Article] Serum metabolic profiles of the tryptophan-kynurenine pathway in the high risk subjects of major depressive disorder2020
- Author(s)
  Sakurai Masashi、Yamamoto Yasuko、Kanayama Noriyo、Hasegawa Masaya、Mouri Akihiro、Takemura Masao、Matsunami Hidetoshi、Miyauchi Tomoya、Tokura Tatsuya、Kimura Hiroyuki、Ito Mikiko、Umemura Eri、(Boku) Aiji Sato、Nagashima Wataru、Tonoike Takashi、Kurita Kenichi、Ozaki Norio、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1961-1961
- DOI
  10.1038/s41598-020-58806-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-19K17108, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K10325, KAKENHI-PROJECT-18K19761
[Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2020
- Author(s)
  Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 26 Issue: 9 Pages: 918-932
- DOI
  10.3748/wjg.v26.i9.918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
[Journal Article] Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice.2020
- Author(s)
  Hoshi M, Osawa Y, Nakamoto K, Morita N, Yamamoto Y, Ando T, Tashita C, Nabeshima T, Saito K.
- Journal Title
  
  Toxicology
  
  Volume: 438 Pages: 152458-152458
- DOI
  10.1016/j.tox.2020.152458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873, KAKENHI-PROJECT-17H04252
[Journal Article] Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus2020
- Author(s)
  Wulaer Bolati、Kunisawa Kazuo、Hada Kazuhiro、Jaya Suento Willy、Kubota Hisayoshi、Iida Tsubasa、Kosuge Aika、Nagai Taku、Yamada Kiyofumi、Nitta Atsumi、Yamamoto Yasuko、Saito Kuniaki、Mouri Akihiro、Nabeshima Toshitaka
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 157 Issue: 3 Pages: 642-655
- DOI
  10.1111/jnc.15022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K16679
[Journal Article] Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms2019
- Author(s)
  Teshigawara Tomoaki、Mouri Akihiro、Kubo Hisako、Nakamura Yukako、Shiino Tomoko、Okada Takashi、Morikawa Mako、Nabeshima Toshitaka、Ozaki Norio、Yamamoto Yasuko、Saito Kuniaki
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 255 Pages: 168-176
- DOI
  10.1016/j.jad.2019.05.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K16375, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-16K10248
[Journal Article] Effect of antidepressant treatment on plasma levels of neuroinflammation-associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region2019
- Author(s)
  Tomoya Miyauchia, Tatsuya Tokuraa,*, Hiroyuki Kimuraa, Mikiko Itob, Eri Umemurab, Aiji Sato (boku)c, Wataru Nagashimad, Takashi Tonoikee, Yasuko Yamamotof, Kuniaki Saitof,g, Kenichi Kuritab, Norio Ozaki
- Journal Title
  
  Human Psychopharmacology: Clinical & Experimental
  
  Volume: 34 Issue: 4
- DOI
  10.1002/hup.2698
- NAID
  120006767392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10325, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K17108
[Journal Article] Indoleamine 2,3‐dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma2019
- Author(s)
  Yamasuge Wakana、Yamamoto Yasuko、Fujigaki Hidetsugu、Hoshi Masato、Nakamoto Kentaro、Kunisawa Kazuo、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 10 Pages: 3061-3067
- DOI
  10.1111/cas.14179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-18K15377
[Journal Article] Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression2019
- Author(s)
  Lu Qiaohui、Mouri Akihiro、Yang Yang、Kunisawa Kazuo、Teshigawara Tomoaki、Hirakawa Mami、Mori Yuko、Yamamoto Yasuko、Libo Zou、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 372 Pages: 112053-112053
- DOI
  10.1016/j.bbr.2019.112053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-18K15377
[Journal Article] Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia2019
- Author(s)
  Fujigaki Hidetsugu、Mouri Akihiro、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Neurochemistry International
  
  Volume: 125 Pages: 1-6
- DOI
  10.1016/j.neuint.2019.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969
[Journal Article] Mice deficient in protein tyrosine phosphatase receptor type Z (PTPRZ) show reduced responsivity to methamphetamine despite an enhanced response to novelty2019
- Author(s)
  Fujikawa Akihiro、Noda Yukihiro、Yamamoto Hideko、Tanga Naomi、Sakaguchi Gaku、Hattori Satoko、Song Wen-Jie、Sora Ichiro、Nabeshima Toshitaka、Katsuura Goro、Noda Masaharu
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 8 Pages: e0221205-e0221205
- DOI
  10.1371/journal.pone.0221205
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06908, KAKENHI-PUBLICLY-19H05222, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H05659
[Journal Article] Alteration of specific cytokine expression patterns in patients with breast cancer.2019
- Author(s)
  Kawaguchi K, Sakurai M, Yamamoto Y, Suzuki E, Tsuda M, Kataoka TR, Hirata M, Nishie M, Nojiri T, Kumazoe M, Saito K, Toi M.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 2924-2924
- DOI
  10.1038/s41598-019-39476-9
- NAID
  120006578938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07014, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222
[Journal Article] Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues2019
- Author(s)
  Yoshida Yukihiro、Fujigaki Hidetsugu、Kato Koichi、Yamazaki Kyoka、Fujigaki Suwako、Kunisawa Kazuo、Yamamoto Yasuko、Mouri Akihiro、Oda Akifumi、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10243-10243
- DOI
  10.1038/s41598-019-46666-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K08257, KAKENHI-PROJECT-18K15377
[Journal Article] Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes.2018
- Author(s)
  A Sobue, N Ito, T Nagai, W Shan, K Hada, Nakajima A, Y Murakami, A Mouri, Y Yamamoto, T Nabeshima, K Saito, K Yamada
- Journal Title
  
  Glia
  
  Volume: 66 Issue: 5 Pages: 1034-52
- DOI
  10.1002/glia.23299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-15H03086
[Journal Article] Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia.2018
- Author(s)
  Sobue A, Kushima I, Nagai T, Shan W, Kohno T, Aleksic B, Aoyama Y, Mori D, Arioka Y, Kawano N, Yamamoto M, Hattori M, Nabeshima T, Yamada K, Ozaki N.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 13046-13046
- DOI
  10.1038/s41598-018-31390-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08281, KAKENHI-PROJECT-17K10295, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H03985, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-17K19500
[Journal Article] Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling2018
- Author(s)
  Yamamoto Yasuko、Yamasuge Wakana、Imai Shinjiro、Kunisawa Kazuo、Hoshi Masato、Fujigaki Hidetsugu、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 15917-15917
- DOI
  10.1038/s41598-018-34166-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K15377
[Journal Article] Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice.2017
- Author(s)
  Kubo H, Hoshi M, Matsumoto T, Irie M, Oura S, Tsutsumi H, Hata Y, Yamamoto Y, Saito K
- Journal Title
  
  Lipids Health Dis.
  
  Volume: 16(1) Issue: 1 Pages: 106-106
- DOI
  10.1186/s12944-017-0501-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-15H03086
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017
- Author(s)
  Ohta Y , Kubo H , Yashiro K , Ohashi K , Tsuzuki Y , Wada N , Yamamoto Y , Saito, K
- Journal Title
  
  JOURNAL OF PHYSIOLOGICAL SCIENCES
  
  Volume: 67 Pages: 361-372
- NAID
  40021176369
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice2017
- Author(s)
  Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K.
- Journal Title
  
  IMMUNOLOGY LETTERS
  
  Volume: 181 Pages: 94-100
- DOI
  10.1016/j.imlet.2016.11.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860376, KAKENHI-PROJECT-16K10195
[Journal Article] Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas.2017
- Author(s)
  Yamamoto Y, Goto N, Takemura M, Yamasuge W, Yabe K, Takami T, Miyazaki T, Takeuchi T, Shiraki M, Shimizu M, Adachi S, Saito K, Shibata Y, Nakamura N, Hara T, Serrero G, Saito K, Tsurumi H.
- Journal Title
  
  Clin Chim Acta
  
  Volume: 473 Pages: 139-146
- DOI
  10.1016/j.cca.2017.07.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09920, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-15H03086
[Journal Article] Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions2017
- Author(s)
  Tashiro T , Murakami Y , Mouri A , Imamura Y, Nabeshima T, Yamamoto, Y , Saito, K
- Journal Title
  
  BEHAVIOURAL BRAIN RESEARCH
  
  Volume: 317 Pages: 279-285
- DOI
  10.1016/j.bbr.2016.09.050
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H04364
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017
- Author(s)
  Ohta, Y ; Kubo, H ; Yashiro, K ; Ohashi, K ; Tsuzuki, Y ; Wada, N ; Yamamoto, Y ; Saito, K
- Journal Title
  
  JOURNAL OF PHYSIOLOGICAL SCIENCES 4.巻 67 5.発行年 2017
  
  Volume: 4 Pages: 361-372
- NAID
  40021176369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460675
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues.2017
- Author(s)
  Ohta Y, Kubo H, Yashiro K, Ohashi K, Tsuzuki Y, Wada N, Yamamoto Y, Saito K.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 67(3) Issue: 3 Pages: 361-372
- DOI
  10.1007/s12576-016-0467-y
- NAID
  40021176369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-15H03086
[Journal Article] Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1.2016
- Author(s)
  Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K.
- Journal Title
  
  SCIENTIFIC REPORTS
  
  Volume: 6 Issue: 1 Pages: 29920-29920
- DOI
  10.1038/srep29920
- NAID
  120006323748
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-15H04100, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences.2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K
- Journal Title
  
  Neuropharmacology.
  
  Volume: 印刷中 Pages: 264-274
- DOI
  10.1016/j.neuropharm.2016.01.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860379, KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences. Neuropharmacology.2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K.
- Journal Title
  
  j.neuropharm.
  
  Volume: S0028-3908(16) Pages: 30011-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] Effects of various phytochemicals on indoleamine 2, 3-dioxygenase 1 activity : galanal is a novel, competitive inhibitor of the enzyme2014
- Author(s)
  Yamamoto R, Yamamoto Y, Imai S, Fukutomi R, Ozawa Y, Abe M, Matuo Y, Saito K
- Journal Title
  
  PLoS One
  
  Volume: 12;9(2) Issue: 2 Pages: e88789-e88789
- DOI
  10.1371/journal.pone.0088789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Remarkable role of indoleamine 2, 3-dioxygenase and tryptophan metabolites in infectious diseases : potential role in macrophage-mediated inflammatory diseases2013
- Author(s)
  Murakami Y, Hoshi M, Imamura Y, Arioka Y, Yamamoto Y, Saito K
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2013 Pages: 391984-391984
- DOI
  10.1155/2013/391984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790621, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-24890270
[Journal Article] Acquired resistance of leukemic cells to AraC is associated with the upregulation of aldehyde dehydrogenase 1 family member A2.2013
- Author(s)
  Kawasoe M, Yamamoto Y, Okawa K, Funato T, Takeda M, Hara T, Tsurumi H, Moriwaki H, Arioka Y, Takemura M, Matsunami H, Markey SP, Saito K.
- Journal Title
  
  Exp Hematol.
  
  Volume: 41(7) Issue: 7 Pages: 597-603
- DOI
  10.1016/j.exphem.2013.03.004
- NAID
  120005302084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] L-tryptophan-kynurenine pathway metabolites regulate type 1 IFNs of acute viral myocarditis in mice2012
- Author(s)
  Hoshi M
- Journal Title
  
  J Immunol
  
  Volume: 188 Issue: 8 Pages: 3980-3987
- DOI
  10.4049/jimmunol.1100997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] L-Tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice2012
- Author(s)
  Hoshi M, Yamamoto Y, Saito K, 他4名
- Journal Title
  
  J Immunol
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Studies on tissue and cellular distribution of indoleamine 2, 3-dioxygenase 2 : the absence of IDO1 upregulates IDO2 expression in the epididymis2012
- Author(s)
  Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, Saito K
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 60(11) Issue: 11 Pages: 854-60
- DOI
  10.1369/0022155412458926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Inhibition of increased indoleamine 2, 3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection2012
- Author(s)
  Murakami Y, Hoshi M, Hara A, Takemura M, Arioka Y, Yamamoto Y, Matsunami H, Funato T, Seishima M, Saito K
- Journal Title
  
  Cytokine
  
  Volume: 59(2) Issue: 2 Pages: 245-51
- DOI
  10.1016/j.cyto.2012.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma.2005
- Author(s)
  Yamamoto Y, Hirakawa E, Mori S, Hamada Y, Kawaguchi N, Matsuura N.
- Journal Title
  
  Biochem Biophys Res Commun. Jul 22;333(1):
  
  Pages: 223-229
- Data Source
  KAKENHI-PROJECT-16790240
[Patent] 関節リューマチ患者における生物学的製剤の有効性の予測方法2013
- Inventor(s)
  斉藤邦明, 坪井彩, 山本康子
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2013-127092
- Filing Date
  2013-06-18
- Data Source
  KAKENHI-PROJECT-23390149
[Patent] 関節リウマチ患者における生物学的製剤の有効性の予測方法
- Inventor(s)
  斉藤邦明、山本康子、坪井彩
- Data Source
  KAKENHI-PROJECT-23790621
[Presentation] 暦年的なデータベースを用いた機械学習による高血圧予備群の予測2023
- Author(s)
  水谷宗慈、山本康子、竹村正男、藤垣英嗣、齋藤邦明
- Organizer
  第63回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-22K11891
[Presentation] 質量分析計を用いた新型コロナウイルス感染症患者血清中のトリプトファン代謝産物一斉定量解析2023
- Author(s)
  藤垣英嗣、高尾明日香、杉浦彩香、藤垣朱和子、生野彰宏、山本康子、齋藤邦明
- Organizer
  第42回日本トリプトファン研究会学術集会
- Data Source
  KAKENHI-PROJECT-23K27843
[Presentation] ワクチン接種による免疫獲得者とハイブリッド免疫獲得者の血清中抗SARS-C0V-2抗体価の推移の違い2023
- Author(s)
  杉浦彩香、藤垣英嗣、高尾明日香、加藤詩緒、水谷宗慈、山本康子、竹村正男、齋藤邦明
- Organizer
  日本医療検査科学会第55回大会
- Data Source
  KAKENHI-PROJECT-23K27843
[Presentation] 生化学自動分析装置JCA-BM9130を用いた新型コロナウイルス抗体検査試薬「SARS-CoV-2 UTAB FS」の有用性の検討2022
- Author(s)
  藤垣英嗣, 竹村正男, 齊藤翠, 藤田孝, 山本康子, 齋藤邦明
- Organizer
  医学と薬学
- Data Source
  KAKENHI-PROJECT-22K11891
[Presentation] 高食塩負荷による高血圧および情動・認知機能障害はPGE2/EP1-タウリン酸化シグナルが関与している2022
- Author(s)
  窪田悠力、毛利彰宏、國澤和生、長谷川眞也、倉橋仁美、小菅愛加、山本康子、手塚裕之、釘田雅則、長尾静子、齊藤邦明、鍋島俊隆
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 常染色劣性多発性嚢胞腎症モデル動物PCKラットの腎臓におけるトリプトファン代謝産物の解析2022
- Author(s)
  釘田雅則, 熊本海生航, 吉村文, 白水貴大, 藤垣英嗣, 山本康子, 高橋和男, 湯澤由紀夫, 長尾静子
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08345
[Presentation] 慢性予測不能軽度ストレスによるうつ様行動および視床下部-下垂体-副腎系の調節不全はキヌレニン-3-モノオキシゲナーゼ発現低下によるキヌレン酸の増加が関与している2022
- Author(s)
  長谷川眞也、毛利彰宏、國澤和生、窪田悠力、倉橋仁美、小菅愛加、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] ADVIA Centaur XPTによるIL-6測定の基礎的検討と臨床的意義関節リウマチ患者を対象に検討2022
- Author(s)
  石田秀和, 竹村正男, 佐藤正夫, 山本康子, 藤垣英嗣, 佐々木智裕, 森本剛史, 酒井昭嘉, 伊藤弘康, 斉藤邦明
- Organizer
  医療検査と自動化
- Data Source
  KAKENHI-PROJECT-22K11891
[Presentation] ミロイド β注入による認知機能低下におけるトリプトファン代謝を介した興奮－抑制バランスの関与（優秀賞受賞）2021
- Author(s)
  倉橋仁美、毛利彰宏、國澤和生、窪田悠力、長谷川眞也、山本康子、齋藤邦明、鍋島俊隆ア
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 慢性社会的敗北ストレスにより誘発されるうつ様行動において小脳血液‐脳関門の破綻が関与する2021
- Author(s)
  小菅愛加、國澤和生、手塚裕之、星　雅人、森田那奈架、河合智貴、山本康子、齋藤邦明、鍋島俊隆、毛利彰宏
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Indoleamine 2,3-dioxygenase 2 (IDO2)欠失による乾癬病態増悪のメカニズム解明2021
- Author(s)
  酒井里佳, 山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第15回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] 前頭前皮質のmiR-874-3pはIDO1抑制を介してLPS誘発性のうつ様行動を緩解する2021
- Author(s)
  國澤和生, Suento Willy Jaya, Wulaer Bolati, 小菅愛加, 飯田翼, 藤垣英嗣, 山本康子, Tanra Andi Jayalangkara, 齋藤邦明, 鍋島俊隆, 毛利彰宏
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] MAGE-D1遺伝子欠損マウスに認められるうつ様行動におけるノルアドレナリン神経系の関与2021
- Author(s)
  毛利彰宏, 平川茉実, 横山美里, 渡辺研, 木村真理, 磯部凌輔, 國澤和生, 森優子, 山本康子, 野田幸裕, 齋藤邦明, 鍋島俊隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 慢性的な社会的敗北ストレスによるうつ様行動は, ミクログリアの活性化を介した脳梁の髄鞘異常を伴う2021
- Author(s)
  菅原侑実香, 國澤和生, 飯田翼, 齋藤成, 小菅愛加, Bolati Wulaer, 山本康子, 齋藤邦明, 毛利彰宏, 鍋島俊隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Cysteine conjugate beta-lyase1 阻害剤によるCisplatin 誘発性腎障害保護効果2021
- Author(s)
  助田菜緒，藤垣英嗣，安藤穂乃実，山本康子，齋藤邦明
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K05757
[Presentation] Indoleamine 2,3-dioxygenase 2 (IDO2)欠失による乾癬病態増悪のメカニズム解明2021
- Author(s)
  酒井里佳, 山本康子、藤垣英嗣、齋藤邦明
- Organizer
  日本トリプトファン研究会第40回学術集会
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] ビフィズス菌の加熱殺菌体は慢性社会的敗北ストレスにより誘発されるうつ様行動及びインターロイキン１βの発現を抑制する2021
- Author(s)
  國澤和生、小菅愛加、菅原侑実香、篠原香月、飯田　翼、Bolati Wulaer、河合智貴、藤垣英嗣、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 高食塩負荷により惹起される高血圧および行動異常は末梢炎症反応を伴う2021
- Author(s)
  窪田悠力, 毛利彰宏, 國澤和生, 長谷川眞也, 倉橋仁美, 山本康子, 手塚裕之, 釘田雅則, 長尾静子, 齋藤邦明, 鍋島俊隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 社会的敗北ストレスは前頭前皮質でのGLT-1ユビキチン化低下を介して, うつ様行動を誘発する2021
- Author(s)
  小菅愛加, 國澤和生, 飯田翼, Wulaer Bolati, Suento Willy Jaya, 山本康子, 齋藤邦明, 毛利彰宏, 鍋島俊隆：
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] ニコチンは血清コルチコステロン量の増加を介した慢性予測不能軽度ストレスによるうつ様行動を緩解する2021
- Author(s)
  長谷川眞也, 毛利彰宏, 國澤和生, 窪田悠力, 倉橋仁美, 山本康子, 齋藤邦明, 鍋島俊隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] QPRTの欠損はキノリン酸によるドパミン作動性神経系における酸化ストレスを増強し、連動・認知機能障害を惹起する2021
- Author(s)
  毛利彰宏、新島　萌、國澤和生、髙野一輝、山田雅之、勅使河原知明、窪田悠力、平川茉実、森　優子、星　雅人、藤垣英嗣、山本康子、長谷川眞也、倉橋仁美、齋藤邦明、鍋島俊隆
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 慢性予測不能軽度ストレスによる行動変化におけるミクログリアに関連したキヌレニン代謝の関与2021
- Author(s)
  長谷川眞也、毛利彰宏、國澤和生、窪田悠力、倉橋仁美、山本康子、齋藤邦明、鍋島俊隆；
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] QPRTの欠損はキノリン酸によるドパミン作動性神経系における酸化ストレスを介した運動・認知機能障害を惹起する．2020
- Author(s)
  毛利彰宏、新島萌、勅使河原知明、國澤和生、窪田悠力、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  第９３回日本薬理学会年会（2020.3.16-18横浜）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝酵素Indoleamine 2,3-dioxygenase 2欠損が脳内に及ぼす影響2020
- Author(s)
  石川雅樹、山本康子, 藤垣英嗣, 毛利彰宏, 國澤和生, 鍋島俊隆, 齋藤邦明
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝酵素　indoleamine 2,3-dioxygenase 2欠損が脳内に及ぼす影響2020
- Author(s)
  石川雅樹、山本康子、齋藤邦明
- Organizer
  第60回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] トリプトファン代謝酵素　indoleamine 2,3-dioxygenase 2欠損が脳内に及ぼす影響2020
- Author(s)
  石川雅樹、山本康子、齋藤邦明
- Organizer
  第60回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 疾患バイオマーカーとしてのトリプトファン ― キヌレニン経路2020
- Author(s)
  山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第67回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07490
[Presentation] 疾患バイオマーカーとしてのトリプトファン ― キヌレニン経路2020
- Author(s)
  山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] IDO1は社会的敗北ストレス下におけるストレス脆弱性を制御する/ IDO1 regulates vulnerability to social defeat stress.2019
- Author(s)
  國澤和生、毛利彰宏、小菅愛加、飯田翼、Wulaer Bolati、山本康子、齋藤邦明、鍋島俊隆：
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会合同大会（2019.7.25-28　新潟）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] The deficit of quinolinic acid phosphoribosyltransferase induces hypolocomotion and cognitive impairment through impairment of dopaminergic neuronal function2019
- Author(s)
  Moe Niijima, Akihiro Mouri, Tomoaki Teshigawara, Kazuo Kunisawa, Hisayoshi Kubota, Mami Hirakawa, Yuko Mori, Masato Hoshi, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] IDO1 regulates vulnerability to social defeat stress2019
- Author(s)
  國澤和生、毛利彰宏、小菅愛加、飯田翼、Wulaer Bolati、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  NEURO2019（2019/7/25-28新潟）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Repeated social defeat stress induces depression-like behavior through the decrease of GLT-1 ubiquitination in the prefrontal cortex of mice．2019
- Author(s)
  Aika Kosuge, Kazuo Kunisawa, Tsubasa Iida, Bolati Wulaer, Willy Jaya Suento, Yasuko Yamamoto, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Repeated social defeat stress induces microglial activation and myelin abnormality in the corpus callosum: a potential link to depression-like behavior.2019
- Author(s)
  Tsubasa Iida, Kazuo Kunisawa, Sei Saitoh, Aika Kosuge, Bolati Wulaer, Willy Jaya Suento, Yasuko Yamamoto, Akihiro Mouri, Kuniaki Saito and Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Involvement of Noradrenergic Function in the Behavioral Changes in MAGE-D1 KO Mice2019
- Author(s)
  毛利彰宏、平川茉実、渡辺研、國澤和生、森優子、窪田悠力、新島萌、山本康子、野田幸裕、鍋島俊隆、齋藤邦明
- Organizer
  NEURO2019（2019/7/25-28新潟）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 慢性予測不能軽度ストレス負荷は側坐核のドパミン機能亢進と前頭皮質・海馬のセロトニン機能低下を伴ううつ様行動を惹起する2019
- Author(s)
  毛利彰宏、キョヘイル、ヤンヤン、國澤和生、勅使河原知明、平川茉実、森優子、山本康子、シュウリボ、鍋島俊隆、齋藤邦明
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 人工知能を用いたストレス負荷マウスの表情評価.2019
- Author(s)
  多田遼矢，毛利彰宏，寺本篤司，國澤和生，山田あゆみ，長谷川眞也，倉橋仁美，浅野僚子，窪田悠力，新島萌，山本康子，齋藤邦明，鍋島俊隆
- Organizer
  日本生体医工学会東海支部大会（2019.10.26名古屋）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] The role of tryptophan metabolism in major depressive disorder2019
- Author(s)
  Kazuo Kunisawa, Akihiro Mouri, Aika Kosuge, Tsubasa Iida, Bolati Wulaer, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Deficiency of kynurenine 3-monooxygenase increases vulnerability to the PCP-induced behavioral abnormalities2019
- Author(s)
  Hisayoshi Kubota, Akihiro Mouri, Kazuo Kunisawa, Moe Niijima, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Antidepressant effects of XJ-Et-8 in mice chronically exposed to corticosterone2019
- Author(s)
  Jiajing Shan, Akihiro Mouri, Yang Yang, Qiaohui Lu, Kazuo Kunisawa , Tomoaki Teshigawara , Mami Hirakawa , Yuko Mori , Yasuko Yamamoto , Zou Libo , Toshitaka Nabeshima, Kuniaki Saito,
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Involvement of Noradrenergic Function in the Behavioral Changes in MAGE-D1 KO Mice.2019
- Author(s)
  毛利彰宏、平川茉実、渡辺研、國澤和生、森優子、窪田悠力、新島萌、山本康子、野田幸裕、鍋島俊隆、齋藤邦明
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会合同大会（2019.7.25-28　新潟）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-、2019
- Author(s)
  毛利彰宏、國澤和生、窪田悠力、新島萌、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019（2019.8.31東京）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Development of biomarker for depression focused on serotonergic systems from animal models.2019
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-2019
- Author(s)
  毛利彰宏、國澤和生、窪田悠力、新島萌、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019（2019/8/31東京）
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] IDO1は社会的敗北ストレス下におけるストレス脆弱性を制御する2019
- Author(s)
  國澤和生毛利彰宏小菅愛加飯田翼 Wulaer Bolati 山本康子齋藤邦明鍋島俊隆
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会合同大会（2019/7/24-27新潟）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Kynurenine 3-monooxygenase regulates expression of depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptor by kynurenic acid. AsCNP2019 (2019.10.11-13, 福岡)2019
- Author(s)
  Akihiro Mouri, Yuko Mori, Kazuo Kunisawa, Mami Hirakawa, Tomoaki Teshigawara, Hisayoshi Kubota, Moe Niijima, Hidetsugu Fujigaki, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Involvement of kynurenine 3-monooxygenase in the vulnerability to the PCP-induced behavioral abnormalities2018
- Author(s)
  Hisayoshi Kubota, Akihiro Mouri, Kazuo Kunisawa, Moe Niijima, Tomoaki Teshigawara, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Toshitaka Nabeshima ,Kuniaki Saito
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex2018
- Author(s)
  Akihiro Mouri,Tomoyuki Furuyashiki, Kazuo Kunisawa, Yasuko Yamamoto, Kiyofumi Yamada, Yukihiro Noda, Kuniaki Saito, Shu Narumiya, Toshitaka Nabeshima
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 薬学研究が支える臨床化学精神疾患モデル動物研究からのバイオマーカー研究　薬学・医学から臨床化学へのトランスレーショナル研究2018
- Author(s)
  毛利彰宏, 國澤和生, 山本康子, 齋藤邦明, 鍋島俊隆
- Organizer
  第５８回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Lipopolysaccharide shock reveals the immune function of indoleamine 2, 3-dioxygenase 2 through regulation of IL-6/STAT3 signalling.2018
- Author(s)
  1.Yasuko Yamamoto, Wakana Yamasuge, Shinjiro Imai, Kazuo Kunisawa, Masato Hoshi, Hidetsugu Fujigaki, Akihiro Mouri, Toshitaka Nabeshima, Kuniaki Saito.
- Organizer
  15th International Society for Tryptophan Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] DEVELOPMENT OF ANIMAL MODELS AND BIOMARKER FOR DEPRESSION FOCUSED ON SEROTONERGIC SYSTEMS2018
- Author(s)
  Akihiro Mouri1, Kazuo Kunisawa2, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Development of kynurenine aminotransferase II inhibitor screening assay.2018
- Author(s)
  2.Kyoka Yamazaki, Hidetsugu Fujigaki, Yukihiro Yoshida, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito.
- Organizer
  15th International Society for Tryptophan Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] 酵素反応を用いたキノリン酸測定法の開発2018
- Author(s)
  山崎杏佳, 藤垣英嗣, 吉田幸弘, 木村文香, 山本康子, 齋藤邦明
- Organizer
  第５８回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Development of animal models and biomarker for depression focused on serotonergic systems2018
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto , Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Repeated social defeat induces social interaction deficits associated with the alteration of kynurenine pathway activity in the prefrontal cortex2018
- Author(s)
  Kazuo Kunisawa, Akihiro Mouri, Aika Kosuge, Tsubasa Iida, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] ストレス(モデル)と分子うつ病発症におけるトリプトファン代謝の関与2018
- Author(s)
  國澤和生, 毛利彰宏, 山本康子, 齋藤邦明, 鍋島俊隆
- Organizer
  第34回日本ストレス学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 神経精神疾患の病態メカニズムに基づく新たな治療分子標的トリプトファン代謝に注目したうつ病病態解明と診断・治療薬戦略2018
- Author(s)
  毛利彰宏, 國澤和生, 山本康子, 藤垣英嗣, 齋藤邦明, 鍋島俊隆
- Organizer
  第２８回日本臨床精神神経薬理学会・第４８回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] MAGE-D1 REGULATES EXPRESSION OF DEPRESSION-LIKE BEHAVIOR THROUGH SEROTONIN TRANSPORTER UBIQUITYLATION2018
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Mami Hirakawa, Yuko Mori, Ken Watanabe, Hidetsugu Fujigaki, Yasuko Yamamoto, Yukihiro Noda, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Kynurenine 3-monooxygenase is essential for de novo biosynthesis of NAD+.2018
- Author(s)
  3.Yukihiro Yoshida, Hidetsugu Fujigaki, Yasuko Yamamoto, Kyoka Yamazaki, Fumika Kimura, Hisako Kubo, Tsutomu Fukuwatari, Toshitaka Nabeshima, Kuniaki Saito.
- Organizer
  15th International Society for Tryptophan Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex2018
- Author(s)
  Akihiro Mouri, Tomoyuki Furuyashiki, Kazuo Kunisawa, Yasuko Yamamoto, Kiyofumi Yamada, Yukihiro Noda, Kuniaki Saito, Shu Narumiya, TOshitaka Nabeshima
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] うつ病発症におけるトリプトファン代謝の関与2018
- Author(s)
  國澤和生、毛利彰宏、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  第３４回日本ストレス学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 糖尿病モデルマウスにおけるキヌレニン経路代謝物の腎組織イメージング質量分析2018
- Author(s)
  松下祥子, 高橋和男, 伊藤辰将, 山本康子, 藤垣英嗣, 毛利彰宏, 中嶋和紀, 尾之内高慶, 辰川英樹, 釘田雅則, 長尾静子, 人見清隆, 齋藤邦明, 瀬藤光利, 湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 酵素法を用いたキヌレニン定量法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討．2017
- Author(s)
  藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 酵素法を用いたキヌレニン定量法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
- Organizer
  第38回日本トリプトファン研究会学術集
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
- Organizer
  第38回日本トリプトファン研究会学術集
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討．2017
- Author(s)
  藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] アストログリアにおけるMHCIの発現とその行動学的・神経病理学的影響2017
- Author(s)
  祖父江顕,伊藤教道,羽田和弘,中島晶,村上由希,毛利彰宏,山本康子,鍋島俊隆,齋藤邦明,永井拓,山田清文
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Absence of kynurenine 3-monooxygebase reduces mortality of accute viral myocarditis in mice2016
- Author(s)
  久保緋紗子、星雅人、毛利彰宏、田下智栄子、勅使河原知明、山菅和可菜、和田直也、山本康子、鍋島俊隆、毛利彰宏
- Organizer
  第37回日本トリプトファン研究開学術集会
- Place of Presentation
  東京農業大学
- Data Source
  KAKENHI-PROJECT-26460675
[Presentation] 周産期における抑うつにおけるユビキチン化セロトニントランスポーターの変化2016
- Author(s)
  毛利彰宏、椎野智子、勅使河原知明、山本康子、野田幸裕、尾崎紀夫、齋藤邦明、鍋島俊隆　「
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Absence of kynurenine 3-monooxygebase reduces mortality of accute viral myocarditis in mice2016
- Author(s)
  久保緋紗子、星雅人、毛利彰宏、田下智栄子、勅使河原知明、山菅和可菜、和田直也、山本康子、鍋島俊隆、毛利彰宏
- Organizer
  第37回日本トリプトファン研究開学術集会
- Place of Presentation
  東京農業大学
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] マウス致死性敗血症モデルにおけるインドールアミン酸素添加酵素の役割について」2016
- Author(s)
  星雅人、久保緋紗子、毛利彰宏、勅使河原知明、山菅和可菜、和田直也、山本康子、鍋島俊隆、毛利彰宏
- Organizer
  第37回日本トリプトファン研究開学術集会
- Place of Presentation
  東京農業大学
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016
- Author(s)
  勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016
- Author(s)
  勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-26460675
[Presentation] Increased serum GP88(progranulin) concentration in rheumatoid arthritis.2015
- Author(s)
  Yamamoto　Y, Saito K
- Organizer
  IFCC Paris
- Place of Presentation
  Le Palais des Congres de paris(France)
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] RA患者におけるバイオマーカー GP88の検討2015
- Author(s)
  竹村正男、佐藤正夫、山本康子、斎藤邦明
- Organizer
  第27回中部リウマチ学会
- Place of Presentation
  ウインクあいち（名古屋市）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] 関節リウマチ症例における血清Progranulinの測定2015
- Author(s)
  山本康子, 竹村正男, 佐藤正夫, 斉藤邦明
- Organizer
  第55回日本臨床化学会
- Place of Presentation
  大阪大学コンベンションセンター（吹田市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of indoleamine 2,3-dioxygenase 12013
- Author(s)
  S Imai, R Yamamoto, Y Yamamoto, Y Katayanagi, R Fukutomi, M Abe, Y Ozawa, K Saito
- Organizer
  15thInternational Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 免疫調節因子インドールアミン 2,3-ジオキシゲナーゼ1の新規阻害剤探索：フィトケミカルを中心として2013
- Author(s)
  山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 免疫調節因子インドールアミン 2, 3-ジオキシゲナーゼ1の新規阻害剤探索 : フィトケミカルを中心として2013
- Author(s)
  山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
- Organizer
  第36回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of in doleamine 2, 3-dioxygenase 12013
- Author(s)
  Imai, R Yamamoto, Y Yamamoto, Y Katayan agi, R Fukutomi, M Abe, Y Ozawa, K Saito
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390149

1. SAITOU Kuniaki (80262765)

# of Collaborated Projects: 12 results

# of Collaborated Products: 96 results
2. Fujigaki Hidetsugu (00612631)

# of Collaborated Projects: 8 results

# of Collaborated Products: 28 results
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Yamamoto Yasuko 山本 康子

YAMAMOTO Yasuko 山本 康子

山本 康子 ヤマモト ヤスコ

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Indoleamine 2’3-dioxygenase 2が関与する炎症慢性化機構の解明Principal Investigator

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Deficiency of indoleamine 2,3-dioxygenase 2 is associated with the development of lifestyle-related diseases.Principal Investigator

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Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through regulation of IL-6/stat3 signallingPrincipal Investigator

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Antitumor efficacies of indoleamine 2,3-dioxygenase 2 in lewis lung carcinoma mice model.Principal Investigator

Yamamoto Yasuko 山本康子

YAMAMOTO Yasuko 山本康子

山本康子ヤマモトヤスコ