KAKU RYUJI 賀来隆治

… Alternative Names

Kaku Ryuji 賀来隆治

Ryuji Kaku 賀来隆治

KAKU Ryuji 賀来隆治

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Researcher Number	50444659
Other IDs
Affiliation (Current)	2025: 三重大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 三重大学, 医学系研究科, 教授 2021: 岡山大学, 医歯薬学域, 講師 2018 – 2020: 岡山大学, 医歯薬学総合研究科, 講師 2017: 岡山大学, 医学部・歯学部附属病院, 助教 2015: 岡山大学, 医歯(薬)学総合研究科, 助教 … More 2013: 岡山大学, 医歯薬学総合研究科, 助教 2012 – 2013: 岡山大学, 医歯(薬)学総合研究科, 助教 2012: 岡山大学, 大学院・医歯薬学総合研究科, 助教 2011: 岡山大学, 大学病院, 助教 2010: 岡山大学, 岡山大学病院, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / Anesthesiology/Resuscitation studies Except Principal Investigator Basic Section 55050:Anesthesiology-related / Basic Section 55060:Emergency medicine-related / Anesthesiology / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 慢性痛 / 慢性疼痛 / 神経障害性痛 / ペースメーカーチャンネル / 遺伝子治療 / 下行性疼痛抑制系 / 術後遷延痛 / グルタミン酸トランスポーター / 痛みの遺伝子治療 / グリコシル化 / 神経因性疼痛 … More Except Principal Investigator … More 難治性疼痛 / 医療・福祉 / バーチャルリアリティ / M2マクロファージ / 集中治療後慢性痛 / 慢性疼痛 / ILC2 / インテグリン / エクソソーム / ICUせん妄 / 好酸球 / miRNA / PD-L1 / 心停止後症候群 / エキソソーム / M2 マクロファージ / Neuregulin / 神経障害性痛 / 化学療法誘発性末梢神経障害 / リハビリテーション / ユーザインターフェース / 人工知能 / 認知科学 Less

Elucidation of the molecular mechanism by which eosinophil-derived exosomes cause ICU delirium
- Principal Investigator
  
  奥野郁斗
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Mie University
Therapeutic effects of lidocaine-induced M2 microglia-derived exosomes on chronic pain after intensive care.
- Principal Investigator
  
  竹内俊吾
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Mie University
Development of a novel treatment and prognostic model for post-cardiac arrest syndrome using the M2 Macrophage Designer Exosome
- Principal Investigator
  
  川本英嗣
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Mie University
Study on the role of spinal glutamate transporter in prolonged postoperative painPrincipal Investigator
- Principal Investigator
  
  Kaku Ryuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Mie University
  Okayama University
Splice-variant specific knock-down of Neuregline 1 as a treatment for chemotherapy-induced peripheral neuropathy
- Principal Investigator
  
  Matsuoka Yoshikazu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Okayama University
Optimization of Virtual reality mirror visual feedback therapy with Internet of things and artificial intelligence
- Principal Investigator
  
  sato kenji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Kawasaki Medical School
Gene Therapy for Chronic pain by modulating the SNPs of pacemaker ion channels.Principal Investigator
- Principal Investigator
  
  Ryuji Kaku
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Okayama University
an application of on-demand virtual reality mirror visual feedback therapy to patients with intractable chronic pain
- Principal Investigator
  
  SATO kenji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Gene therapy for neuropathic pain applying SNP pace maker ion-channel (HCN channel) transduction to the spinal cord and dorsal root ganglionPrincipal Investigator
- Principal Investigator
  
  KAKU Ryuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University

All 2023 2022 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Correlation Between the Social Network Structure and Well-Being of Health Care Workers in Intensive Care Units: Prospective Observational Study2023
- Author(s)
  Esumi Ryo、Ito-Masui Asami、Kawamoto Eiji、Ito Mami、Hayashi Tomoyo、Shinkai Toru、Hane Atsuya、Okuno Fumito、Park Eun Jeong、Kaku Ryuji、Shimaoka Motomu
- Journal Title
  
  Interactive Journal of Medical Research
  
  Volume: 12 Pages: e50148-e50148
- DOI
  10.2196/50148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17858, KAKENHI-PROJECT-19KK0224, KAKENHI-PROJECT-21K09015, KAKENHI-PROJECT-21K09070, KAKENHI-PROJECT-22K09117, KAKENHI-PROJECT-22K09138, KAKENHI-PROJECT-22K09160, KAKENHI-PROJECT-23K08440, KAKENHI-PROJECT-21K08995, KAKENHI-PROJECT-20K17859
[Journal Article] Prolonged Double-Low Time and the Incidence of Postoperative Delirium in Surgical ICU Patients2023
- Author(s)
  Yamanoi T, Suzuki S, Kaku R, Morimatsu H.
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 77 Issue: 2 Pages: 161-167
- DOI
  10.18926/AMO/65145
- URL
  https://ousar.lib.okayama-u.ac.jp/65145
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08995
[Journal Article] Phentolamine-induced spinal GLT-1 upregulation improve mirror image pain in SNI model rat2022
- Author(s)
  Kosuke Nakatsuka, Yoshikazu Matsuoka, Masako Kurita, Ruilin Wan, Chika Tsuboi, Nobutaka Sue, Ryuii Kaku, and Hiroshi Morimatsu
- Journal Title
  
  Acta Med Okayama
  
  Volume: 76 Pages: 255-263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08995
[Journal Article] Spinal nerve injury causes upregulation of ErbB2 and ErbB3 receptors in rat dorsal root ganglia2013
- Author(s)
  Mizobuchi S 、 Kanzaki H 、 Omiya H 、Matsuoka Y、Obata N、Kaku R、Nakajima H、Ouchida M、Morita K
- Journal Title
  
  J Pain Res
  
  Volume: 6巻 Pages: 87-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791433
[Journal Article] Expression changes of the neuregulin 1 isoforms in neuropathic pain model rats2012
- Author(s)
  Kanzaki H、Mizobuchi S、Obata N、Itano Y、Kaku R、Tomotsuka N、Nakajima H、Ouchida M、Nakatsuka H、Maeshima K、Morita K
- Journal Title
  
  Neurosci Lett
  
  Volume: 508巻 Pages: 78-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791433
[Journal Article] Antinociceptive effects of intrathecal landiolol injection in a rat formalin pain model2012
- Author(s)
  Mizobuchi S、Matsuoka Y、Obata N、Kaku R、Itano Y、Tomotsuka N、Taniguchi A、Nishie H、Kanzaki H、Ouchida M、Morita K
- Journal Title
  
  Acta Med Okayama
  
  Volume: 66巻 Pages: 285-289
- NAID
  120004247100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791433
[Journal Article] Extracellular regulated kinase 5 mediated renal protection against ischemia-reperfusion injury2012
- Author(s)
  Kawakami T、Park SW、Kaku R、Yang J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418巻 Pages: 603-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791433
[Journal Article] Decoy strategy targeting the brain-derived neurotrophic factor exon I to attenuate tactile allodynia in the neuropathic pain model of rats2011
- Author(s)
  Obata N、Mizobuchi S、Itano Y、Matsuoka Y、Kaku R、Tomotsuka N、Morita K、Kanzaki H、Ouchida M、Yokoyama M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 408巻 Pages: 139-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791433
[Presentation] Change of BDNF Expression in the Dorsal Root Ganglion of the Bone Cancer Pain Model2012
- Author(s)
  Tomotsuka N、Kaku R、Taniguchi A、Obata N、Matsuoka Y、Mizobuchi S、Sato T、Ichikawa H、Morita K
- Organizer
  American Society of Anesthesiologists Annual meeting
- Place of Presentation
  ワシントンDC、USA
- Year and Date
  2012-10-14
- Data Source
  KAKENHI-PROJECT-22791433
[Presentation] Decoy strategy targeting the Brain-derived neurotrophic factor Exon I suppress pain behavior in rat inflammatory pain model2012
- Author(s)
  Taniguchi A、Kaku R、Tomotsuka N、Omiya H 、 Ishii N 、 Obata N 、 Matsuoka Y 、Mizobuchi S、Morita K
- Organizer
  American Society of Anesthesiologists Annual meeting
- Place of Presentation
  ワシントンDC、USA
- Year and Date
  2012-10-14
- Data Source
  KAKENHI-PROJECT-22791433
[Presentation] HCNチャンネルの転写後調節による細胞膜表面への発現調節に関する検討2010
- Author(s)
  賀来隆治、小幡典彦、友塚直人、板野義太郎、溝渕知司、森田潔
- Organizer
  日本疼痛学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-22791433
[Presentation] Role of the Cyclic AMP in Glycosylation and Plasma Membrane Targeting of the HCN Ion Channels2010
- Author(s)
  Kaku R、Obata N、Kanzaki H、Yang J、Morita K
- Organizer
  American Society of Anesthesiologists Annual meeting
- Place of Presentation
  サンディエゴ、USA
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-22791433
[Presentation] HCNチャンネルの転写後調節による細胞膜表面への発現調節に関する検討2010
- Author(s)
  賀来隆治
- Organizer
  第32回日本疼痛学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-22791433
[Presentation] Role of the Cyclic AMP in Glycosylation and Plasma Membrane Targeting of the HCN Ion Channels2010
- Author(s)
  賀来隆治
- Organizer
  2010米国麻酔学会学術総会
- Place of Presentation
  サンディエゴ
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-22791433

1. 川本英嗣 (20577415)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. SATO kenji (70359884)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. GOFUKU Akio (20170475)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Matsuoka Yoshikazu (20509434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 松崎孝 (10423328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 島岡要 (40281133)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NISHIE Hiroyuki (20379788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIZUHARA Hiroaki (30392137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OBATA Norihiko (30509443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 杉原太郎 (50401948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 朴恩正 (20644587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高娃阿栄 (50643805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 奥野郁斗 (90895517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 赤間悠一 (40763313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 竹内俊吾 (61008512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 江角亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAKU RYUJI 賀来 隆治

Kaku Ryuji 賀来 隆治

Ryuji Kaku 賀来 隆治

KAKU Ryuji 賀来 隆治

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism by which eosinophil-derived exosomes cause ICU delirium

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic effects of lidocaine-induced M2 microglia-derived exosomes on chronic pain after intensive care.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel treatment and prognostic model for post-cardiac arrest syndrome using the M2 Macrophage Designer Exosome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the role of spinal glutamate transporter in prolonged postoperative painPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Splice-variant specific knock-down of Neuregline 1 as a treatment for chemotherapy-induced peripheral neuropathy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optimization of Virtual reality mirror visual feedback therapy with Internet of things and artificial intelligence

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene Therapy for Chronic pain by modulating the SNPs of pacemaker ion channels.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

an application of on-demand virtual reality mirror visual feedback therapy to patients with intractable chronic pain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy for neuropathic pain applying SNP pace maker ion-channel (HCN channel) transduction to the spinal cord and dorsal root ganglionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Correlation Between the Social Network Structure and Well-Being of Health Care Workers in Intensive Care Units: Prospective Observational Study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prolonged Double-Low Time and the Incidence of Postoperative Delirium in Surgical ICU Patients2023

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Journal Article] Phentolamine-induced spinal GLT-1 upregulation improve mirror image pain in SNI model rat2022

Author(s)

Journal Title

Data Source

[Journal Article] Spinal nerve injury causes upregulation of ErbB2 and ErbB3 receptors in rat dorsal root ganglia2013

Author(s)

Journal Title

KAKU RYUJI 賀来隆治

Kaku Ryuji 賀来隆治

Ryuji Kaku 賀来隆治

KAKU Ryuji 賀来隆治

[Presentation] HCNチャンネルの転写後調節による細胞膜表面への発現調節に関する検討2010