Mizuguchi Kenji 水口賢司

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MUZUGUCHI Kenji 水口賢司

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Researcher Number	50450896
Other IDs	https://orcid.org/0000-0003-3021-7078
Affiliation (Current)	2025: 大阪大学, 蛋白質研究所, 教授 2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 AI健康・医薬研究センター, 客員研究員
Affiliation (based on the past Project Information) *help	2020 – 2025: 大阪大学, 蛋白質研究所, 教授 2019: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 AI健康・医薬研究センター, センター長 2017 – 2018: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所バイオインフォマティクスプロジェクト, プロジェクトリーダー 2015: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所バイオインフォマティクスプロジェクト, プロジェクトリーダー 2015: 国立研究開発法人医薬基盤, 健康・栄養研究所・医薬基盤研究所バイオインフォマティクスプロジェクト, プロジェクトリーダー 2014 – 2015: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所バイオインフォマティクスプロジェクト, プロジェクトリーダー 2013 – 2014: 独立行政法人医薬基盤研究所, 創薬基盤研究部, プロジェクトリーダー
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related / System genome science Except Principal Investigator Pathological medical chemistry / Transformative Research Areas, Section (III) / Medium-sized Section 37:Biomolecular chemistry and related fields / Tumor biology and related fields
Keywords	Principal Investigator 創薬ターゲット / タンパク質構造ダイナミクス / 構造インフォマティクス / バイオインフォマティクス / タンパク質間相互作用 / エンリッチメント解析 / KEGGパスウェイ / 統合データベース / 代謝物情報 / トランスオミックス解析 / タンパク質相互作用 / データベース … More Except Principal Investigator … More 計算科学 / 神経変性疾患 / tumor suppressor / breast cancer / ゲノム / 癌 / 分子進化 / 高速AFM / アミロイド / RNA結合タンパク質 / 国際共同研究 / αシヌクレイン / ドラッグデリバリーシステム / 核酸医薬 / エクソソーム / アプタマー / 創薬 / HER2 / がん特異的発現亢進因子 / がん抑制因子 / ミトコンドリア / 乳がん / タンパク相互作用阻害 / multistep carcinogenesis / drug discovery / プロテオーム / タンパク質 / 生体機能利用 / mitochondrial regulation / oncogenic signaling / dephosphorylation / phosphorylation / estrogen signaling / ゲノム創薬 / ホルモン療法耐性 / システムバイオロジー / エストロゲン / 乳癌 / ホルモン / 蛋白質 Less

リン酸化プロテオームデータを用いたキナーゼ－基質相互作用予測とネットワーク構築Principal Investigator
- Principal Investigator
  
  水口賢司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  The University of Osaka
[Amyloid and protein] Comprehensive search and validation of meta-aggregates by molecular evolutionary method
- Principal Investigator
  
  村上一馬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Extracting information about protein dynamics by learning the local environments of static structuresPrincipal Investigator
- Principal Investigator
  
  水口賢司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Osaka University
International research project on nucleic acid aptamers and their exosome-based application to therapeutics for synucleinopathy
- Principal Investigator
  
  Murakami Kazuma
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyoto University
Improved identification of drug targets by data warehousing and simulations of signal transduction pathwaysPrincipal Investigator
- Principal Investigator
  
  Mizuguchi Kenji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  System genome science
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Drug discovery in breast cancer utilizing reactivation of tumor suppressors
- Principal Investigator
  
  KATAGIRI Toyomasa
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  The University of Tokushima
Clarification of novel pathophysiological roles of BIG3 in breast cancer cells
- Principal Investigator
  
  KATAGIRI Toyomasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Drug development and biological function study of novel estrogen receptor activity modulator BIG3 protein
- Principal Investigator
  
  KATAGIRI Toyomasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Development of a target discovery platform by integrating data warehousing and protein function predictionPrincipal Investigator
- Principal Investigator
  
  Mizuguchi Kenji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  System genome science
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition

All 2022 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Structural dynamics of the N‐terminal SH2 domain of PI3K in its free and CD28‐bound states2022
- Author(s)
  Hosoe Yuhi、Miyanoiri Yohei、Re Suyong、Ochi Saki、Asahina Yuya、Kawakami Toru、Kuroda Masataka、Mizuguchi Kenji、Oda Masayuki
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 9 Pages: 2366-2378
- DOI
  10.1111/febs.16666
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24942
[Journal Article] Data Warehousing with TargetMine for Omics Data Analysis2019
- Author(s)
  Chen Y.A., Tripathi L.P., Mizuguchi K.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1986 Pages: 35-64
- DOI
  10.1007/978-1-4939-9442-7_3
- ISBN
  9781493994410, 9781493994427
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Integrative Analysis of Multi-Omics Data2019
- Author(s)
  Tripathi L.P., Esaki T.,　Itoh M., Chen Y.A, Mizuguchi K.
- Journal Title
  
  Encyclopedia of Bioinformatics and Computational Biology
  
  Volume: 3 Pages: 194-199
- DOI
  10.1016/b978-0-12-809633-8.20096-4
- ISBN
  9780128114322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Data Warehousing with TargetMine for Omics Data Analysis2019
- Author(s)
  Chen Y.A., Tripathi L.P., Mizuguchi K.
- Journal Title
  
  Methods Molecular Biology 1986(Microarray Bioinformatics)
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Assessing drug target suitability using Targetmine2019
- Author(s)
  Chen Y.A., Yogo E., Kurihara N., Ohno T., Higuchi C., Rokushima M., Mizuguchi K.
- Journal Title
  
  F1000Research
  
  Volume: 8 Pages: 233-233
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] The TargetMine data warehouse: enhancement and updates2019
- Author(s)
  Chen Y.A., Tripathi L.P., Fujiwara T., Kameyama T., Ito M., Mizuguchi K.
- Journal Title
  
  Frontiers in Genetics-Bioinformatics and Computational Biology
  
  Volume: 10 Pages: 934-934
- DOI
  10.3389/fgene.2019.00934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] 創薬における計算機の果たす役割 -プレシジョンメディシンに向けて-2018
- Author(s)
  長尾知生子, 夏目やよい, 水口賢司
- Journal Title
  
  Precision Medicine
  
  Volume: 1(1) Pages: 28-31
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] TargetMineによる標的予測2018
- Author(s)
  夏目やよい, 相崎健一, 北嶋聡, 陳怡安, 水口賢司, 菅野純
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 43
- NAID
  130007432170
- Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Integrating sequence and gene expression information predicts genome-wide DNA-binding proteins and suggests a cooperative mechanism2018
- Author(s)
  Ahmad Shandar、Prathipati Philip、Tripathi Lokesh P、Chen Yi-An、Arya Ajay、Murakami Yoichi、Mizuguchi Kenji
- Journal Title
  
  Nucleic Acids Research
  
  Volume: ４６ Issue: 1 Pages: 54-70
- DOI
  10.1093/nar/gkx1166
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging2018
- Author(s)
  Jin Y, Takeda Y, Kondo Y, Tripathi LP, Kang S, Takeshita H, Kuhara H, Maeda Y, Higashiguchi M, Miyake K, Morimura O、Koba T、Hayama Y、Koyama S、Nakanishi K、Iwasaki T、Tetsumoto Si、Tsujino K、Kuroyama M、Iwahori K、Hirata H、Takimoto Ti、Suzuki M、Nagatomo I、Sugimoto K、Fujii Y、Kida H、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5145-5145
- DOI
  10.1038/s41598-018-23338-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K09580, KAKENHI-PROJECT-17K07268, KAKENHI-PROJECT-15K09219, KAKENHI-PROJECT-16K19451
[Journal Article] Network-based analysis for biological discovery2018
- Author(s)
  Tripathi Lokesh P.、Murakami Yoichi、Chen Yi-An.、Mizuguchi Kenji
- Journal Title
  
  Encyclopedia of Bioinformatics and Computational Biology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Integrative analysis of Multi-omics data2018
- Author(s)
  Tripathi Lokesh P.、Esaki Tsuyoshi、Ito Mari、Chen Yi-An.、Mizuguchi Kenji
- Journal Title
  
  Encyclopedia of Bioinformatics and Computational Biology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.2017
- Author(s)
  Yoshimaru T, Ono M, Bando Y, Chen YA, Mizuguchi K, Shima H, Komatsu M, Imoto I, Izumi K, Honda J, Miyoshi Y, Sasa M, Katagiri T
- Journal Title
  
  Nature Communications
  
  Volume: 印刷中 Issue: 1 Pages: 15427-15427
- DOI
  10.1038/ncomms15427
- NAID
  120006535065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-16H01575, KAKENHI-PROJECT-16H05153
[Journal Article] PSOPIA: Toward more reliable protein-protein interaction prediction from sequence information2017
- Author(s)
  Murakami Yoichi、Mizuguchi Kenji
- Journal Title
  
  IEEE Conferences
  
  Volume: - Pages: 255-261
- DOI
  10.1109/iciibms.2017.8279749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] Making protein-protein interaction prediction more reliable with a large-scale dataset at the proteome level2017
- Author(s)
  Murakami Yoichi、Mizuguchi Kenji
- Journal Title
  
  Journal of Bioinformatics and Neuroscience
  
  Volume: 3 Pages: 91-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] ―創薬への応用を目指して―2017
- Author(s)
  伊藤眞里、長尾知生子、夏目やよい、水口賢司
- Journal Title
  
  CICSJ Bulletin
  
  Volume: 35 Issue: 3 Pages: 210
- DOI
  10.11546/cicsj.35.210
- NAID
  130006792845
- ISSN
  0913-3747, 1347-2283
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] A-kinase anchoring protein BIG3 coordinates oestrogen signaling in breast cancer cells2017
- Author(s)
  〇Yoshimaru T, Ono M, Bando Y, Chen YA, Mizuguchi K, Shima H, Komatsu M, Imoto I, Izumi K, Honda J, Miyoshi Y, Sasa M, Katagiri T*
- Journal Title
  
  Nature Communications
  
  Volume: 印刷中
- NAID
  120006535065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05153
[Journal Article] Database Development and Computational Modelling in Early-Stage Drug Discovery2017
- Author(s)
  水口賢司
- Journal Title
  
  TRENDS IN THE SCIENCES
  
  Volume: 22 Issue: 7 Pages: 7_62-7_65
- DOI
  10.5363/tits.22.7_62
- NAID
  130006882503
- ISSN
  1342-3363, 1884-7080
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-17K07268
[Journal Article] The diversity of H3 loops determines the antigen-binding tendencies of antibody CDR loops2016
- Author(s)
  Tsuchiya Y., Mizuguchi K.
- Journal Title
  
  Protein Sci
  
  Volume: 25 Issue: 4 Pages: 815-825
- DOI
  10.1002/pro.2874
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] An integrative data analysis platform for gene set analysis and knowledge discovery in a data warehouse framework2016
- Author(s)
  Chen Y. A., Tripathi L. P., Mizuguchi K.
- Journal Title
  
  Database (Oxford)
  
  Volume: - Pages: baw009-baw009
- DOI
  10.1093/database/baw009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] BIG3 inhibit the estrogen-dependent nuclear translocation of PHB2 via multiple Karyopherin-alpha proteins in breast cancer cells.2015
- Author(s)
  Kim NH, Yoshimaru T, Chen YA, Matsuo T, Komatsu M, Miyoshi Y, Tanaka E, Sasa M, Katagiri T
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0127707-e0127707
- DOI
  10.1371/journal.pone.0127707
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-25293079
[Journal Article] Profiles of microRNA networks in intestinal epithelial cells in a mouse model of colitis.2015
- Author(s)
  Lee J, Park EJ, Yuki Y, Ahmad S, Mizuguchi K, Ishii KJ, Shimaoka M, Kiyono H.
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 18174-18174
- DOI
  10.1038/srep18174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-25430186
[Journal Article] Integration of Ligand and Structure Based Approaches for CSAR-20142015
- Author(s)
  Prathipati P., Mizuguchi K.
- Journal Title
  
  J. Chem. Inf. Model
  
  Volume: - Issue: 6 Pages: 974-987
- DOI
  10.1021/acs.jcim.5b00477
- NAID
  120007001200
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Systems Biology Approaches to a Rational Drug Discovery Paradigm2015
- Author(s)
  Prathipati P., Mizuguchi K.
- Journal Title
  
  Current Topics in Medicinal Chemistry
  
  Volume: 16(9) Issue: 9 Pages: 1009-1025
- DOI
  10.2174/1568026615666150826114524
- NAID
  120007001199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target2015
- Author(s)
  Chiba S, Akiyama Y, Sekijima M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 1-13
- DOI
  10.1038/srep17209
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24240044, KAKENHI-PROJECT-15H02776, KAKENHI-PROJECT-15J11261, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-26730152, KAKENHI-PUBLICLY-26120528
[Journal Article] Retinoblastoma Binding Protein 4-Regulated Classical Nuclear Transport Is Involved in Cellular Senescence2015
- Author(s)
  Tsujii A., Miyamoto Y., Moriyama T., Tsuchiya T., Obuse C., Mizuguchi K., Oka M., Yoneda Y.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 49 Pages: 29375-29388
- DOI
  10.1074/jbc.m115.681908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-26870341, KAKENHI-PROJECT-25430186, KAKENHI-PLANNED-25116004, KAKENHI-PLANNED-25116008
[Journal Article] Integration of Disease Entries Across OMIM, Orphanet, and a Proprietary Knowledge Base2015
- Author(s)
  Ito M., Nakagawa S., Mizuguchi K., Okumura T.
- Journal Title
  
  Current Approaches in Applied Artificial Intelligence (Lecture Note in Computer Science)
  
  Volume: 9101 Pages: 120-130
- DOI
  10.1007/978-3-319-19066-2_12
- ISBN
  9783319190655, 9783319190662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Dextran sulfate-resistant A/Puerto Rico/8/34 influenza virus is associated with the emergence of specific mutations in the neuraminidase glycoprotein2014
- Author(s)
  Yamada H, Nagao C, Haredy AM, Mori Y, Mizuguchi K, Yamanishi K, Okamoto S
- Journal Title
  
  Antiviral Research
  
  Volume: 111 Pages: 69-77
- DOI
  10.1016/j.antiviral.2014.09.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580441, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-26462806
[Journal Article] 計算生物学によるシステムの理解から創薬へ、2014
- Author(s)
  水口賢司
- Journal Title
  
  生命科学から創薬へのイノベーション
  
  Volume: 1 Pages: 82-88
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Sagace 創薬・疾患研究のためのデータベース横断検索サービス2014
- Author(s)
  水口賢司、伊藤真和吏
- Journal Title
  
  今日から使える！データベース・ウェブツール達人になるための実践ガイド
  
  Volume: 1 Pages: 60-61
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Prediction of detailed enzyme functions and identification of specificity determining residues by random forests2014
- Author(s)
  Nagao C., Nagano N., Mizuguchi K.
- Journal Title
  
  PloS One
  
  Volume: 9 Issue: 1 Pages: e84623-e84623
- DOI
  10.1371/journal.pone.0084623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] High-resolution modeling of antibody structures by a combination of bioinformatics, expert knowledge, and molecular simulations.2014
- Author(s)
  Hiroki Shirai, Kazuyoshi Ikeda, Kazuo Yamashita, Yuko Tsuchiya, Jamica Sarmiento, Shide Liang, Tatsuaki Morokata, Kenji Mizuguchi, Junichi Higo, Daron M. Standley, Haruki Nakamura
- Journal Title
  
  Proteins
  
  Volume: 印刷中 Issue: 8 Pages: 1624-1635
- DOI
  10.1002/prot.24591
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23370071, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118008, KAKENHI-PROJECT-25430186
[Journal Article] Homology-based prodection of interactions between proteins using Averaged One-Dependence Estimators2014
- Author(s)
  Mizuguchi K., Murakami Y.
- Journal Title
  
  BMC bioinformatics
  
  Volume: 15 Issue: 1 Pages: 213-213
- DOI
  10.1186/1471-2105-15-213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-26870045
[Journal Article] Altered Actions of Memantine and NMDA-Induced Currents in a New Grid2-Deleted Mouse Line.2014
- Author(s)
  Ayako Kumagai, Akira Fujita, Tomoki Yokoyama, Yuki Nonobe, Yasuhiro Hasaba, Tsutomu Sasaki, Yumi Itoh, Minako Koura, Osamu Suzuki, Shigeki Adachi, Haruko Ryo, Arihiro Kohara, Lokesh P. Tripathi, Masato Sanosaka, Toshiki Fukushima, Taisei Nomura, Hiroshi Takemori, et al.
- Journal Title
  
  Genes
  
  Volume: 5 Issue: 4 Pages: 1095-1114
- DOI
  10.3390/genes5041095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241023, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-25670155, KAKENHI-PROJECT-25740023, KAKENHI-PROJECT-26430012, KAKENHI-PROJECT-26670196, KAKENHI-PROJECT-24390222
[Journal Article] Crystal structure of FtsA from Staphylococcus aureus2014
- Author(s)
  J. Fujita, Y. Maeda, C. Nagao, Y. Tsuchiya, Y. Miyazaki, M. Hirose, E. Mizohata, Y. Matsumoto, T. Inoue, K. Mizuguchi, and H. Matsumura
- Journal Title
  
  FEBS Lett.
  
  Volume: 588 Issue: 10 Pages: 1879-1885
- DOI
  10.1016/j.febslet.2014.04.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25121719, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-25440022, KAKENHI-PUBLICLY-26102526
[Journal Article] Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure2014
- Author(s)
  Mizuguchi K., Chen Y. A., Murakami Y., Ahmad S., Yoshimaru T., Katagri T.
- Journal Title
  
  BMC Res Notes
  
  Volume: 7 Issue: 1 Pages: 435-435
- DOI
  10.1186/1756-0500-7-435
- NAID
  120006864075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-26870045
[Journal Article] Integrated pathway clusters with coherent biological themes for target prioritisation.2014
- Author(s)
  Chen YA.,Tripathi LP.,Dessailly BH.,Nyström-Persson J.,Ahmad S.,Mizuguchi K.,
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 6 Pages: e99030-e99030
- DOI
  10.1371/journal.pone.0099030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells2013
- Author(s)
  T. Yoshimaru, M. Komatsu, T. Matsuo, Y.-A. Chen, Y. Murakami, K. Mizuguchi, E. Mizohata, T. Inoue, M. Akiyama, R. Yamaguchi, S. Imoto, S. Miyano, Y. Miyoshi, M. Sasa, Y. Nakamura, and T. Katagiri
- Journal Title
  
  Nature Communications
  
  Volume: 4 Issue: 1 Pages: 2433-2433
- DOI
  10.1038/ncomms3443
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24109017, KAKENHI-PUBLICLY-25134712, KAKENHI-PROJECT-25293079, KAKENHI-PROJECT-25430186
[Journal Article] Understanding the biological context of NS5A-host interactions in HCV infection: a network-based approach.2013
- Author(s)
  Tripathi LP, Kambara H, Chen YA, Nishimura Y, Moriishi K, Okamoto T, Morita E, Abe T, Mori Y, Matsuura Y, Mizuguchi K
- Journal Title
  
  J Proteome Res
  
  Volume: 12 Issue: 6 Pages: 2537-2551
- DOI
  10.1021/pr3011217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659204, KAKENHI-PROJECT-25430186
[Journal Article] Functional site plasticity in domain superfamilies2013
- Author(s)
  Dessailly B.H., Dawson N.L., Mizuguchi K., Orengo C.A.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1834 Issue: 5 Pages: 874-89
- DOI
  10.1016/j.bbapap.2013.02.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430186
[Journal Article] Toxygates: Interactive Toxicity Analysis on a Hybrid Microarray and Linked Data Platform2013
- Author(s)
  Johan Nyström-Persson, Yoshinobu Igarashi, Maori Ito, Mizuki Morita, Noriyuki Nakatsu, Hiroshi Yamada, Kenji Mizuguchi
- Journal Title
  
  Bioinformatics
  
  Volume: 29 Issue: 23 Pages: 3080-3086
- DOI
  10.1093/bioinformatics/btt531
- NAID
  130005468755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700300, KAKENHI-PROJECT-25430186
[Presentation] 創薬研究へのAI活用2020
- Author(s)
  水口賢司
- Organizer
  ILSI Japan先端技術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 疾患・創薬研究におけるデータベースとAI活用2020
- Author(s)
  水口賢司
- Organizer
  日本臨床試験学会　第１１回学術集会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] インフォマティクスの活用による新薬創出の加速を目指して2019
- Author(s)
  水口賢司
- Organizer
  第５回インターフェックス大阪
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 計算生物学と創薬のためのデータ統合2019
- Author(s)
  水口賢司
- Organizer
  シンポジウム「理論生物物理学の現在と未来」
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] データ統合と人工知能技術による新薬創出の加速2019
- Author(s)
  水口賢司
- Organizer
  彩都産学官連携フォーラム 2019
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] ＡＩ開発基盤としてのデータ統合：薬物動態モデリングとターゲット探索2019
- Author(s)
  水口賢司
- Organizer
  第１回日本メディカルＡＩ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] AI創薬の基礎としてのデータ統合とモデリング2019
- Author(s)
  水口賢司
- Organizer
  第６回NPO法人京都コモンズ会員セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] データ統合と計算システム生物学による創薬2019
- Author(s)
  水口賢司
- Organizer
  バイオインタラクション研究会第４回ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] AI創薬基盤としてのデータ統合とデータベース開発2019
- Author(s)
  水口賢司
- Organizer
  ゲノム創薬・創発フォーラム第１回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Artificial intelligence-based drug discovery: challenges and applications to target identification and pharmacokinetic modelling2019
- Author(s)
  水口賢司
- Organizer
  第４回トランスオミクスシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration as a basis for artificial intelligence in drug discovery2019
- Author(s)
  水口賢司
- Organizer
  第１４回生命医科学研究所ネットワーク国際シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration and computational systems approaches to drug discovery2019
- Author(s)
  水口賢司
- Organizer
  6th International Symposium on Diffraction Structural Biology (ISDSB2019)
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Adding trans-omics analysis features to TargetMine2018
- Author(s)
  Kameyama T., Chen Y.A., Nojima Y., Fujiwara T., Esaki T., Tripathi L., Ito M., Mizuguchi K.
- Organizer
  ＣＢＩ学会2018年大会
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 創薬・健康・栄養研究を支援する支援するNIBIOHNのデータベース2018
- Author(s)
  水口賢司, 坂手龍一, 五十嵐芳暢, 陳怡安, 樋口千洋, 長尾知生子, 深川明子
- Organizer
  第41回日本分子生物学会年会（特別企画バイオデータベースコーナー）
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 創薬・疾患研究のためのデータ統合の実際2018
- Author(s)
  水口賢司
- Organizer
  トーゴーの日シンポジウム2018
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration and computational systems approaches to target discovery and pharmacokinetic modelling2018
- Author(s)
  水口賢司
- Organizer
  日英セミナー Big Data and AI in Drug Discovery: Resources and Developments
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration and computational modelling for drug discovery2018
- Author(s)
  水口賢司
- Organizer
  第６回ITbM国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration as a basis for computational modelling for rational drug discovery2018
- Author(s)
  Mizuguchi K.
- Organizer
  The 18th KIAS Conference on Protein Structure and Function
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 創薬におけるAI利活用2018
- Author(s)
  水口賢司
- Organizer
  ＣＢＩ学会（情報計算化学生物学会）2018年大会（プレナリー講演）
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] タンパク質インフォマティクスのためのデータ統合2018
- Author(s)
  水口賢司
- Organizer
  第18回日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration and computational systems approaches towards rational drug discovery2018
- Author(s)
  水口賢司
- Organizer
  InCoB 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 創薬・健康・栄養研究を支援するNIBIOHNのデータベース2017
- Author(s)
  水口賢司,坂手龍一,深川明子,五十嵐芳暢,陳怡安,樋口千洋,長尾知生子
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] データ統合と多階層モデリングによる創薬の効率化2017
- Author(s)
  水口賢司
- Organizer
  徳島大学研究クラスター統合的がん創薬研究クラスター　特別セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] Data integration and statistical/ab initio modeling towards rational drug discovery2017
- Author(s)
  水口賢司
- Organizer
  The 55th Annual Meeting of the Biophysical Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 多階層データの統合モデリングによる薬物動態予測システムの構築2017
- Author(s)
  水口賢司
- Organizer
  CBI学会2017年大会フォーカストセッション
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] タンパク質立体構造の比較とデータベース2017
- Author(s)
  水口賢司
- Organizer
  第386回CBI学会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07268
[Presentation] 構造からネットワークへ：計算生物学による創薬研究2016
- Author(s)
  水口賢司
- Organizer
  日本学術振興会構造生物169委員会　第４９回研究会
- Place of Presentation
  東京
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] A novel A-kinase anchoring protein BIG3, coordinates estrogen signalling in breast cancer cells2016
- Author(s)
  Tetsuro Yoshimaru, Ono Masaya, Mizuguchi Kenji, Miyoshi Yasuo, Mitsunori Sasa and Toyomasa Katagiri
- Organizer
  The 12th International Conference on Protein Phosphatase
- Place of Presentation
  近畿大学　大阪府東大阪市
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05153
[Presentation] Analysis of serum microRNA expression and cytokine production profiles for understanding febrile episodes after vaccination2016
- Author(s)
  Natsume-Kitatani Y., Ozasa K., Nakayama T., Ishii K., Mizuguchi K.
- Organizer
  第９回次世代アジュバント研究会
- Place of Presentation
  大阪
- Year and Date
  2016-01-19
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] アジュバント空間の解析を可能にする統合データベース2016
- Author(s)
  水口賢司
- Organizer
  第9回次世代アジュバント研究会
- Place of Presentation
  大阪
- Year and Date
  2016-01-19
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 健康な日本人の生活習慣と腸管免疫・腸内細菌データベースの構築：バイオインフォマティクスの視点から2016
- Author(s)
  水口賢司
- Organizer
  シリーズ「薬づくりの新しいR&Dモデルを探る」第１１回「薬づくりと健康食品開発を結ぶ」
- Place of Presentation
  東京
- Year and Date
  2016-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 計算生物学による分子認識と生体応答の予測：がん創薬に向けて2015
- Author(s)
  水口賢司
- Organizer
  第２回　次世代がんインフォマティクス研究会
- Place of Presentation
  岡山
- Year and Date
  2015-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] トキシコゲノミクスデータの統合化を目指したOpen TG-GATEsの再RDF化について2015
- Author(s)
  五十嵐芳暢, 伊藤真和吏, 川島秀一, 山田弘, 水口賢司
- Organizer
  トーゴーの日シンポジウム2015
- Place of Presentation
  東京
- Year and Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 医薬基盤・健康・栄養研究所の創薬支援データベースとツール2015
- Author(s)
  水口賢司, 坂手龍一, 深川明子, 五十嵐芳暢, 陳怡安, 長尾知生子
- Organizer
  第38回日本分子生物学会年会　第88回日本分子生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Pose and affinity predictions of fXa,SYK and TrmD ligands for CSAR-2014: application of an integrated ligand and protein structure based approach2015
- Author(s)
  Prathipati P., Mizuguchi K.
- Organizer
  JCUP VI, OpenEye Scientific Software meeting
- Place of Presentation
  東京
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 創薬・疾患研究のためのデータベース検索システム　Sagace & Toxygates2015
- Author(s)
  長尾知生子, 五十嵐芳暢, 森田瑞樹, 陳怡安, 深川明子, 坂手龍一, 水口賢司
- Organizer
  トーゴーの日シンポジウム2015
- Place of Presentation
  東京
- Year and Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] A systems biology framework for the identification of the molecular basis of immune adjuvanticity2015
- Author(s)
  Prathipati P., Aoshi T.,Igarashi K., Mizuguchi K.
- Organizer
  9th Vaccine & ISV Congress
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] A systems level analysis of adjuvant transcriptomes for biomarker and target discovery2015
- Author(s)
  Tripathi L. P., .Ito J., Aoshi T., Ishii J. K., Mizuguchi K.
- Organizer
  9th Vaccine & ISV Congress
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] データウェアハウスによる創薬関連データ統合と解析の実際2015
- Author(s)
  水口賢司
- Organizer
  第361回 CBI学会研究講演会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] データ統合と計算の融合による創薬研究2015
- Author(s)
  水口賢司
- Organizer
  バイオスーパーコンピューティング神戸2015
- Place of Presentation
  神戸
- Year and Date
  2015-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Effective　characterisation of adjuvant transcriptomes for biomarker and target discovery2015
- Author(s)
  Tripathi L.P., Ito J., Aoshi T., Ishii J. K., Mizuguchi K.
- Organizer
  The 12th [BC]2 - the Basel Computational Biology Conference
- Place of Presentation
  バーゼル（スイス）
- Year and Date
  2015-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 創薬の初期研究における統合データウェアハウスTargetMine2015
- Author(s)
  陳怡安，ロケシュテリパチ，水口賢司
- Organizer
  トーゴーの日シンポジウム2015
- Place of Presentation
  東京
- Year and Date
  2015-10-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 計算システム生物学によるポリファーマコロジーへのアプローチと新たな合理的創薬パラダイム2015
- Author(s)
  水口賢司
- Organizer
  CBI学会2015年大会
- Place of Presentation
  東京
- Year and Date
  2015-10-28
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] The integration of biological data and　its application to drug discovery2015
- Author(s)
  Tsuchiya Y., Prathipati P., Mizuguchi K.
- Organizer
  CBI学会2015年大会
- Place of Presentation
  東京
- Year and Date
  2015-10-27
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Ligand-induced conformational changes in STING are essential　for its signal transduction（リガンド結合による構造変化がもたらすSTINGシグナル伝達系への影響）2015
- Author(s)
  土屋裕子，水口賢司
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 創薬・疾患研究への活用に向けたデータベース連携2015
- Author(s)
  坂手龍一, 深川明子, 水口賢司, 山田弘, 塩谷恭子, 松田潤一郎, 宮本恵宏, 梅垣敬三, 小原有弘, 松山晃文
- Organizer
  トーゴーの日シンポジウム2015
- Place of Presentation
  東京
- Year and Date
  2015-10-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] バイオインフォマティクスによるシステムの理解から創薬へ2014
- Author(s)
  水口賢司
- Organizer
  徳島大学　疾患プロテオゲノム研究センター
- Place of Presentation
  徳島
- Year and Date
  2014-05-16
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Integrated pathway clusters for gene set analysis and target prioritization2014
- Author(s)
  陳怡安, Tripathi L., Dessailly B.H., Nystrom J., Ahmad S., 水口賢司,
- Organizer
  トーゴーの日シンポジウム2014
- Place of Presentation
  東京
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 創薬・疾患研究のためのデータベース横断検索システム Sagace2014
- Author(s)
  伊藤真和吏, 森田瑞樹, 五十嵐芳暢, 陳怡安, 長尾知生子, 深川明子, 坂手龍一, 水口賢司
- Organizer
  トーゴーの日シンポジウム2014
- Place of Presentation
  東京
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Toxygates: Applying a Toxicology Software Platform to Wheat 'omics2014
- Author(s)
  Igarashi Y., Morita M., Ito M., Nakatsu N., Yamada H., Mizuguchi K.
- Organizer
  Plant&Genome Asia　2014
- Place of Presentation
  Singapore
- Year and Date
  2014-05-19
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Adjuvant Database Project: comprehensive transcriptome analysis in animal models2014
- Author(s)
  Aoshi T., Nakatsu N., Igarashi Y., Wijaya E., Ito J., Kishishita N., Standley D., Yamada H., Mizuguchi K., Ishii K.,
- Organizer
  Keystone Symposium on The Modes of Action of Vaccine Adjuvants
- Place of Presentation
  Seattle, Washington, USA,
- Year and Date
  2014-10-08
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 計算生物学によるシステムの理解から創薬へ2014
- Author(s)
  水口賢司
- Organizer
  第２回　関西ライフサイエンス・リーディングサイエンティストセミナー
- Place of Presentation
  大阪
- Year and Date
  2014-12-15
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Computational and systems approaches to early stage drug discovery2014
- Author(s)
  水口賢司
- Organizer
  中国科学院上海生命科学研究院
- Place of Presentation
  上海（中国）
- Year and Date
  2014-05-06
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Identification Of Anti-Myxovirus Resistance Protein-1 Autoantibody As A Specific Marker For Idiopathic Nonspecific Interstitial Pneumonia2014
- Author(s)
  Mizuguchi K., Kida H., Nishikawa H., Tripathis L., Ihara S., Arai T., Hirose M., Tada Y., Suenaga T., Mori M., Yano Y., Arase H., Sakaguchi S., Inoue Y., Kumanogoh A.
- Organizer
  EULAR 2014
- Place of Presentation
  Paris
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 抗体デザイン手法の開発に向けた抗原認識機構の解明2014
- Author(s)
  水口賢司、土屋裕子
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 創薬・疾患研究のたまのビッグデータ探索2014
- Author(s)
  水口賢司、　坂手龍一、深川明子、五十嵐芳暢、長尾知生子、陳怡安、伊藤真和吏
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Elucidation of antigen recognition by antibodies toward the development of a method for antibody design2014
- Author(s)
  Mizuguchi K., Tsuchiya Y.
- Organizer
  生命医薬情報学連合大会2014年大会
- Place of Presentation
  仙台
- Year and Date
  2014-10-02
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] アジュバントデータベースの開発とトキシコゲノミクスデータの統合に向けて2014
- Author(s)
  水口賢司、五十嵐芳暢、山田弘、石井健、Nystrom J.,
- Organizer
  トーゴ－の日シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] The Potential of Serum miRNA Signatures to Understand the Immune Responses to Influenza Vaccines Diseases, Systems Biology of Infectious Diseases2014
- Author(s)
  Mizuguchi K., Ito J., Ishii J.
- Organizer
  Systems Biology of Infectious Diseases,
- Place of Presentation
  Seattel, WA,USA
- Year and Date
  2014-08-18
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 創薬・疾患研究のための生物資源・疫学研究データベースの開発2014
- Author(s)
  水口賢司、深川明子、坂手龍一、山田弘、増井徹、塩谷恭子、松田潤一郎、宮本恵宏、松山晃文
- Organizer
  トーゴーの日シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Tosygates　トキシコゲノミクスデータ解析プラットフォームの実装2014
- Author(s)
  水口賢司,五十嵐芳暢, Nystrom J., 森田瑞樹，伊藤真和吏，中津則之，山田弘
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Methods for the Integration of structure based and ligand based approaches to screen ‘Yes kinase inhibitors’2014
- Author(s)
  Prathipati P., Ito J., Tsuchiya Y., Mizuguchi K.
- Organizer
  Level-5
- Place of Presentation
  Tokyo
- Year and Date
  2014-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 乳癌細胞増殖の分子機構解明から創薬へ：タンパク質構造と相互作用予測による主導2014
- Author(s)
  水口賢司
- Organizer
  CBI学会2014年大会
- Place of Presentation
  東京
- Year and Date
  2014-10-29
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 計算生物学による創薬を目指して2014
- Author(s)
  水口賢司
- Organizer
  IPABシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] 抗体デザイン手法の開発に向けた抗原認識機構の解明2014
- Author(s)
  水口賢司、土屋裕子
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Kotai Antibody Builder: Automated, high-resolution structural modeling of antibodies2014
- Author(s)
  Yamashita K., Ikeda K., Sarmiento J., Liang S., Tsuchiya Y., Mizuguchi K., Higo J., Nakamura H., Shirai H., Standley D. M.
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] A random-forest based method that can predict detailed enzyme functions and also identify specificity determining residues
- Author(s)
  長尾知生子, 長野希美, 水口賢司
- Organizer
  CBI学会2013大会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Data integration and protein network analysis for early stage drug discovery
- Author(s)
  水口賢司
- Organizer
  Structural Life Science 7th International Conference on Structural Genomics (ICSG2013-SLS)
- Place of Presentation
  京王プラザホテル（札幌）
- Invited
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] Applications of an integrated data warehouse system to investigate complex biological systems
- Author(s)
  陳怡安, Tripathi L., 水口賢司
- Organizer
  CBI学会2013大会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-25430186
[Presentation] TargetMine, a data warehouse system for target discovery
- Author(s)
  陳怡安, Tripathi L., 水口賢司
- Organizer
  トーゴーの日シンポジウム2013
- Place of Presentation
  時事通信ホール(東京都)
- Data Source
  KAKENHI-PROJECT-25430186

1. KATAGIRI Toyomasa (60291895)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. YOSHIMARU Tetsuro (80424729)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. MATSUSHITA Yosuke (70634450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ONO Masaya (00270900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. OTAKA Akira (20201973)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Murakami Kazuma (80571281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIYOSHI Yasuo (50283784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. MURAKAMI Yoichi (20548424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 伊藤眞里 (50728102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 泉尾直孝 (50722261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂下泰浩 (10972119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 織田昌幸 (20318231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 李秀栄 (50390670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. HIGO Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. AKIYAMA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SEKIJIMA Masakazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. MORITA Mizuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. KIDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 中村努

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井上豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 岡本成史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 山田博司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 島岡要

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 中村春木

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 森石恆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 宮本洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 米田悦啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 岡正啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 梁治子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 野村大成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 松村浩由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizuguchi Kenji 水口 賢司

MUZUGUCHI Kenji 水口 賢司

Research Projects

Research Products

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リン酸化プロテオームデータを用いたキナーゼ－基質相互作用予測とネットワーク構築Principal Investigator

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[Amyloid and protein] Comprehensive search and validation of meta-aggregates by molecular evolutionary method

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Extracting information about protein dynamics by learning the local environments of static structuresPrincipal Investigator

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International research project on nucleic acid aptamers and their exosome-based application to therapeutics for synucleinopathy

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Improved identification of drug targets by data warehousing and simulations of signal transduction pathwaysPrincipal Investigator

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Drug discovery in breast cancer utilizing reactivation of tumor suppressors

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Clarification of novel pathophysiological roles of BIG3 in breast cancer cells

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Drug development and biological function study of novel estrogen receptor activity modulator BIG3 protein

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Development of a target discovery platform by integrating data warehousing and protein function predictionPrincipal Investigator

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[Journal Article] Structural dynamics of the N‐terminal SH2 domain of PI3K in its free and CD28‐bound states2022

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[Journal Article] Data Warehousing with TargetMine for Omics Data Analysis2019

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[Journal Article] Integrative Analysis of Multi-Omics Data2019

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[Journal Article] Data Warehousing with TargetMine for Omics Data Analysis2019

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Mizuguchi Kenji 水口賢司

MUZUGUCHI Kenji 水口賢司