Sugihara Eiji 杉原英志

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SUGIHARA Eiji 杉原英志

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Researcher Number	50464996
Other IDs	https://orcid.org/0000-0002-3233-1045
Affiliation (Current)	2025: 藤田医科大学, 腫瘍医学研究センター, 准教授 2025: 藤田医科大学, オープンファシリティセンター, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 藤田医科大学, オープンファシリティセンター, 准教授 2023: 藤田医科大学, 腫瘍医学研究センター, 准教授 2022: 藤田医科大学, がん医療研究センター, 准教授 2020 – 2021: 藤田医科大学, 共同利用研究設備サポートセンター, 准教授 2019 – 2021: 筑波大学, プレシジョン・メディスン開発研究センター, 准教授 … More 2020: 筑波大学, 学内共同利用施設等, 准教授 2017 – 2018: 筑波大学, 国際産学連携本部, 助教 2016: 慶應義塾大学, 医学部(信濃町), 特任助教 2011 – 2015: 慶應義塾大学, 医学部, 特任助教 2012: 慶應義塾大学, 医学部, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Pathological medical chemistry / Tumor biology Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 54010:Hematology and medical oncology-related / Basic Section 49010:Pathological biochemistry-related / Basic Section 53030:Respiratory medicine-related / Tumor biology
Keywords	Principal Investigator リンパ腫 / MYC / マウスモデル / 治療抵抗性 / 非ホジキンリンパ腫 / 微小残存病変 / ＭYC / 卵巣がん / 急性骨髄性白血病 / DHL … More / 分子標的阻害剤 / BCL2 / Myc / 悪性リンパ腫 / AID / アポトーシス / 免疫回避 / Livin / Fas / 腫瘍免疫 / バーキットリンパ腫 / エピジェネティクス / MEF2B / Ezh2 / c-Myc / エピジェネィクス / シグナル伝達 / 癌幹細胞 / 代謝 / 癌 / 白血病 / 酸化ストレス / CD44 / 白血病幹細胞 … More Except Principal Investigator 肺疾患 / scRNAseq / シングルセル解析 / じん肺 / pneumoconiosis / single-cell RNAseq / マイクロミニピッグ / ブタ / 1細胞解析 / 職業性肺疾患 / 職業性呼吸器疾患 / シングルセルアトラス / 網羅的遺伝子変異解析 / 微小残存病変 / 遺伝子変異解析 / 遺伝子異常 / 微少残存病変 / リキッドバイオプシー / 遺伝子変異 / 悪性リンパ腫 / 始原生殖細胞 / 生殖細胞発生 / 全ゲノムシークエンス / 脳腫瘍 / 胚細胞腫 / レトロトランスポゾン / ロングリードシークエンス / iPSC / 生殖細胞 / ロングリード解析 / iPS細胞 / 全ゲノム解析 / 中枢神経系胚細胞腫 / 病理 / 肺がん / 肺線維症 / 肺線維化 / 肺胞蛋白症 / 呼吸器疾患 / TAS-Seq / 酸化インジウムスズ / 結晶質シリカ / 塵肺 / 職業性疾患 / RCS / シリカ / SITO / インジウム / 動物モデル / 急性リンパ芽球性白血病 / 卵巣がん / 腫瘍免疫 / がん幹細胞 Less

Generation of pneumoconiosis atlas unraveling at 1-cell resolution
- Principal Investigator
  
  山野荘太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  National Institute of Occupational Safety and Health,Japan
  Japan Organization of Occupational Health and Safety Japan Bioassay Research Center
The role of MYC in treatment resistance of acute myeloid leukemiaPrincipal Investigator
- Principal Investigator
  
  杉原英志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Fujita Health University
  University of Tsukuba
Elucidation of the molecular basis of MYC-driven cancers and development of therapeutic strategiesPrincipal Investigator
- Principal Investigator
  
  杉原英志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Fujita Health University
Evaluation of minimal residual disease by liquid biopsy in malignant lymphoma for precise therapeutic stratification.
- Principal Investigator
  
  Tomita Akihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fujita Health University
Comprehensive Fundamental Research on the Onset and Development of Pneumoconiosis Using TAS-Seq
- Principal Investigator
  
  Yamano Shotaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Japan Organization of Occupational Health and Safety Japan Bioassay Research Center
A comprehensive genomic analysis of central nervous system germ cell tumors and generation of their cellular model
- Principal Investigator
  
  ICHIMURA KOICHI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Juntendo University
  National Cancer Center Japan
Integrated elucidation and control of malignant mechanism in MYC-induced lymphomaPrincipal Investigator
- Principal Investigator
  
  Sugihara Eiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Fujita Health University
  University of Tsukuba
Elucidation of molecular mechanism of immune evasion in malignant lymphomaPrincipal Investigator
- Principal Investigator
  
  Sugihara Eiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  University of Tsukuba
  Keio University
Analysis of escaping mechanism from immune system by microenvironment of cancer stem cells
- Principal Investigator
  
  Saya Hideyuki
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Keio University
Analysis of mature B cell lymphomagenes by mutated epigenetic factorsPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Eiji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University
Analysis of CD44 role in metabolism of leukemic stem cellPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Eiji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] In utero tumor development and identification of <i>CTNNB1</i> mutation in a newborn case of ossifying renal tumor of infancy2024
- Author(s)
  Kasai Shin、Tamai Minori、Sugihara Eiji、Oishi Naoki、Hinata Kyoko、Akahane Koshi、Goi Kumiko、Hata Yuko、Kondo Tetsuo、Mitsui Takahiko、Tanaka Mio、Inukai Takeshi
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 71 Issue: 4
- DOI
  10.1002/pbc.30868
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07179
[Journal Article] Clinical application of long‐read nanopore sequencing in a?preimplantation genetic testing pre‐clinical workup to identify the junction for complex Xq chromosome rearrangement‐related disease2023
- Author(s)
  Mariya Tasuku、Shichiri Yui、Sugimoto Takeshi、Kawamura Rie、Miyai Syunsuke、Inagaki Hidehito、Sugihara Eiji、Ikeda Keiko、Baba Tsuyoshi、Ishikawa Aki、Ammae Michiko、Nakaoka Yoshiharu、Saito Tsuyoshi、Sakurai Akihiro、Kurahashi Hiroki
- Journal Title
  
  Prenatal Diagnosis
  
  Volume: 43 Issue: 3 Pages: 304-313
- DOI
  10.1002/pd.6334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-23K08855
[Journal Article] Plant GARDEN: a portal website for cross-searching between different types of genomic and genetic resources in a wide variety of plant species2023
- Author(s)
  Hisako Ichihara, Manabu Yamada, Mitsuyo Kohara, Hideki Hirakawa, Andrea Ghelfi, Takuro Tamura, Akihiro Nakaya, Yasukazu Nakamura, Sachiko Shirasawa, Samatchaya Yamashita, Yosuke Toda, Daijiro Harada, Tsunakazu Fujishiro, Akiko Komaki, Jeffrey A Fawcett, Eiji Sugihara, Satoshi Tabata, Sachiko N Isobe
- Journal Title
  
  BMC Plant Biol.
  
  Volume: 23 Issue: 1 Pages: 391-391
- DOI
  10.1186/s12870-023-04392-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05924, KAKENHI-PROJECT-22K07179
[Journal Article] Growth Transformation of B Cells by Epstein-Barr Virus Requires <i>IMPDH2</i> Induction and Nucleolar Hypertrophy2023
- Author(s)
  Sugimoto Atsuko、Watanabe Takahiro、Matsuoka Kazuhiro、Okuno Yusuke、Yanagi Yusuke、Narita Yohei、Mabuchi Seiyo、Nobusue Hiroyuki、Sugihara Eiji、Hirayama Masaya、Ide Tomihiko、Onouchi Takanori、Sato Yoshitaka、Kanda Teru、Saya Hideyuki、Iwatani Yasumasa、Kimura Hiroshi、Murata Takayuki
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 4
- DOI
  10.1128/spectrum.00440-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07090, KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-22K10520, KAKENHI-PROJECT-23K06568, KAKENHI-PROJECT-21K07131, KAKENHI-PROJECT-21K15449, KAKENHI-PROJECT-22KJ2977, KAKENHI-PROJECT-23K24140, KAKENHI-PROJECT-23K24144
[Journal Article] Estimating copy number to determine BRCA2 deletion status and to expect prognosis in localized prostate cancer2023
- Author(s)
  Nukaya Takuhisa、Sumitomo Makoto、Sugihara Eiji、Takeda Mayu、Nohara Sachio、Tanishima Shigeki、Takenaka Masashi、Zennami Kenji、Takahara Kiyoshi、Shiroki Ryoichi、Saya Hideyuki
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 7 Pages: 8154-8165
- DOI
  10.1002/cam4.5617
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-22K09488
[Journal Article] 特集がん遺伝子の発見は現代医療を進歩させたか Ⅰ.がん遺伝子研究の新しい展開がん悪性形質をつかさどるMYCの新機能と制御2023
- Author(s)
  杉原英志、佐谷秀行
- Journal Title
  
  生体の科学
  
  Volume: 74 Issue: 4 Pages: 316-321
- DOI
  10.11477/mf.2425201700
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2023-08-15
- Data Source
  KAKENHI-PROJECT-22K07179
[Journal Article] Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis2022
- Author(s)
  Uetaki Megumi、Onishi Nobuyuki、Oki Yoshinao、Shimizu Takatsune、Sugihara Eiji、Sampetrean Oltea、Watanabe Takashi、Yanagi Hisano、Suda Kiyoshi、Fujii Hiroya、Kano Koichiro、Saya Hideyuki、Nobusue Hiroyuki
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 33 Issue: 9
- DOI
  10.1091/mbc.e21-12-0609
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07131, KAKENHI-PROJECT-22K07177, KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20K07600
[Journal Article] TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.2022
- Author(s)
  Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato TA, Matsushima K.
- Journal Title
  
  Commun Biol
  
  Volume: 5 Issue: 1 Pages: 602-602
- DOI
  10.1038/s42003-022-03536-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08162, KAKENHI-PROJECT-21K08224, KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-20H03474, KAKENHI-WRAPUP-22H04906
[Journal Article] Pigment epithelium-derived factor promotes peritoneal dissemination of ovarian cancer through induction of immunosuppressive macrophages2022
- Author(s)
  Ueno Sayaka、Sudo Tamotsu、Saya Hideyuki、Sugihara Eiji
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 904-919
- DOI
  10.1038/s42003-022-03837-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-21K19416
[Journal Article] Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo2022
- Author(s)
  Shimizu Takatsune、Sugihara Eiji、Takeshima Hideyuki、Nobusue Hiroyuki、Yamaguchi Rui、Yamaguchi-Iwai Sayaka、Fukuchi Yumi、Ushijima Toshikazu、Muto Akihiro、Saya Hideyuki
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 22 Pages: 3614-3614
- DOI
  10.3390/cells11223614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07131, KAKENHI-PROJECT-21K07134, KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00518
[Journal Article] The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma2020
- Author(s)
  Sugihara Eiji、Hashimoto Norisato、Osuka Satoru、Shimizu Takatsune、Ueno Sayaka、Okazaki Shogo、Yaguchi Tomonori、Kawakami Yutaka、Kosaki Kenjiro、Sato Taka-Aki、Okamoto Shinichiro、Saya Hideyuki
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 20 Pages: 4439-4450
- DOI
  10.1158/0008-5472.can-19-3993
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16315, KAKENHI-PROJECT-19K24054, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-18K07247
[Journal Article] Rock inhibition suppresses osteosarcoma tumorigenesis by inducing terminal adipocyte differentiation in chemoresistant stemlike cells2019
- Author(s)
  1.Takahashi N, Nobusue H, Shimizu T, Sugihara E, Yamaguchi-Iwai S, Onishi N, Kunitomi H, Kuroda T, Saya H
- Journal Title
  
  Cancer Research
  
  Volume: in press Issue: 12 Pages: 3088-3099
- DOI
  10.1158/0008-5472.can-18-2693
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07247, KAKENHI-PROJECT-16J40108, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17H04355, KAKENHI-PROJECT-16H06276
[Journal Article] A periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma2018
- Author(s)
  Semba T、Sugihara E、Kamoshita N、Ueno S、Fukuda K、Yoshino M、Takao K、Yoshikawa K、Izuhara K、Arima Y、Suzuki M、Saya H
- Journal Title
  
  Cancer Sci
  
  Volume: 印刷中 Issue: 5 Pages: 1447-1454
- DOI
  10.1111/cas.13554
- NAID
  120007127783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-16H05343
[Journal Article] T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system2018
- Author(s)
  Tamai Minori、Inukai Takeshi、Kojika Satoru、Abe Masako、Kagami Keiko、Harama Daisuke、Shinohara Tamao、Watanabe Atsushi、Oshiro Hiroko、Akahane Koshi、Goi Kumiko、Sugihara Eiji、Nakada Shinichiro、Sugita Kanji
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 9966-9966
- DOI
  10.1038/s41598-018-27767-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-16K12596, KAKENHI-PROJECT-26241014
[Journal Article] Clofarabine exerts antileukemic activity against cytarabine-resistant B-cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression2018
- Author(s)
  Huang M、Inukai T、Miyake K、Tanaka Y、Kagami K、Abe M、Goto H、Minegishi M、Iwamoto S、Sugihara E、Watanabe A、Somazu S、Shinohara T、Oshiro H、Akahane K、Goi K、Sugita K
- Journal Title
  
  Cancer Med
  
  Volume: 印刷中 Issue: 4 Pages: 1297-1316
- DOI
  10.1002/cam4.1323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-15K09592, KAKENHI-PROJECT-18K07224
[Journal Article] Development of a functional thyroid model based on an organoid culture system.2018
- Author(s)
  Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, Kameyama K, Tsuchihashi K, Sugihara E, Uchino S, Ito K, Kawakubo H, Takeuchi H, Kitagawa Y, Saya H, Nagano O.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 497 Issue: 2 Pages: 783-789
- DOI
  10.1016/j.bbrc.2018.02.154
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07125, KAKENHI-PROJECT-17H03583, KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-17J04061
[Journal Article] Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity.2017
- Author(s)
  Kamel WA, Sugihara E, Nobusue H, Yamaguchi-Iwai S, Onishi N, Maki K, Fukuchi Y, Matsuo K, Muto A, Saya H, Shimizu T.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 16 Issue: 1 Pages: 182-192
- DOI
  10.1158/1535-7163.mct-16-0499
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J40108, KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-15K06845, KAKENHI-PROJECT-16K07125
[Journal Article] FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B cell acute leukemia.2017
- Author(s)
  Ishizawa J, Sugihara E, Kuninaka S, Mogushi K, Kojima K, Benton CB, Zhao R, Chachad D, Hashimoto N, Jacamo RO, Qiu Y, Yoo SY, Okamoto S, Andreeff M, Kornblau SM, Saya H.
- Journal Title
  
  Blood
  
  Volume: 129 Issue: 14 Pages: 1958-1968
- DOI
  10.1182/blood-2016-07-726216
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461425, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15K06840
[Journal Article] CD44 variant-dependent redox status regulation in liver fluke-associated cholangiocarcinoma: a target for CCA treatment.2016
- Author(s)
  Thanee M, Loilome W, Techasen A, Sugihara E, Okazaki S, Abe S, Ueda S, Masuko T, Namwat N, Khuntikeo N, Titapun A, Pairojkul C, Saya H, Yongvanit P.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 7 Pages: 991-1000
- DOI
  10.1111/cas.12967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06840
[Journal Article] Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells.2015
- Author(s)
  Yamaguchi SI, Ueki A, Sugihara E, Onishi N, Yaguchi T, Kawakami Y, Horiuchi K, Morioka H, Matsumoto M, Nakamura M, Muto A, Toyama Y, Saya H, Shimizu T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 7 Pages: 875-882
- DOI
  10.1111/cas.12686
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-15K06845, KAKENHI-PROJECT-15K20161, KAKENHI-PROJECT-26221005
[Journal Article] MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53.2015
- Author(s)
  Fukaya R, Ohta S, Yaguchi T, Matsuzaki Y, Sugihara E, Okano H, Saya H, Kawakami Y, Kawase T, Yoshida K, Toda M.
- Journal Title
  
  Cancer Res
  
  Volume: なし Issue: 9 Pages: 1011-1011
- DOI
  10.1158/0008-5472.can-15-1011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293313, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-15K06840
[Journal Article] Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.2015
- Author(s)
  Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, Saya H, Amagai M, Nagao K.
- Journal Title
  
  Nature Med.
  
  Volume: 21 Issue: 11 Pages: 1272-1279
- DOI
  10.1038/nm.3962
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06840, KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-26253065, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-15K14384
[Journal Article] Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.2015
- Author(s)
  Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0129704-e0129704
- DOI
  10.1371/journal.pone.0129704
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-15K09553, KAKENHI-PROJECT-15K15372, KAKENHI-PROJECT-15K19704, KAKENHI-PROJECT-15K14384, KAKENHI-PROJECT-25293224
[Journal Article] IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress2014
- Author(s)
  Shimizu T, Sugihara E, Yamaguchi-Iwai S, Tamaki S, Koyama Y, Kamel W, Ueki A, Ishikawa T, Chiyoda T, Osuka S, Onishi N, Ikeda H, Kamei J, Matsuo K, Fukuchi Y, Nagai T, Toguchida J, Toyama Y, Muto A, Saya H
- Journal Title
  
  Cancer Res
  
  Volume: 74 Issue: 22 Pages: 6531-6541
- DOI
  10.1158/0008-5472.can-14-0914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J06657, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24390353, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245, KAKENHI-PROJECT-26830082
[Journal Article] Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation.2014
- Author(s)
  Nobusue H
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3368-3368
- DOI
  10.1038/ncomms4368
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130002, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245
[Journal Article] Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells.2014
- Author(s)
  Hosonaga M, Arima Y, Sugihara E, Kohno N and Saya H
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 7 Pages: 779-787
- DOI
  10.1111/cas.12427
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-25461995, KAKENHI-PROJECT-25860245
[Journal Article] Molecular pathogenesis of leukemic stem cell in acute lymphoblastic leukemia2014
- Author(s)
  Sugihara E, Inukai T, Saya H.
- Journal Title
  
  血液内科
  
  Volume: 69 Pages: 595-601
- NAID
  40020262491
- Data Source
  KAKENHI-PROJECT-25860245
[Journal Article] The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs.2013
- Author(s)
  Yuko Atsumi, Aki lnase, Eiji Sugihara, Ryo Sakasai, Hiroaki Fujimori, Hirobumi Teraoka, Hideyuki Saya, Masamoto Kanno, Fumio Tashiro, Hitoshi Nakagami, Mitsuko Masutani, Ken-ichi Yoshioka
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288巻 Issue: 19 Pages: 13269-13277
- DOI
  10.1074/jbc.m112.402560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10618, KAKENHI-PROJECT-22300343, KAKENHI-PROJECT-23501271, KAKENHI-PROJECT-23616003, KAKENHI-PROJECT-25860245
[Journal Article] IGF1 receptor signaling regulates adaptive radioprotection in glioma stemcells2013
- Author(s)
  Osuka S. Sampetrean O, Shimizu T, Saga l, Onishi N, Sugihara E, Okubo J, Fujita S, Takano S, Matsumura A, Saya H
- Journal Title
  
  Stem Cells
  
  Volume: 31 Issue: 4 Pages: 627-640
- DOI
  10.1002/stem.1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00382, KAKENHI-PROJECT-13J06657, KAKENHI-PROJECT-22249055, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-24659645, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245
[Journal Article] Arf/p53 module, which induces apoptosis, downregulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs.2013
- Author(s)
  Atsumi Y, Inase A, Osawa T, Sugihara E, Sakasai R, Fujimori H, Teraoka H, Saya H, Kanno M, Tashiro F, Nakagama H, Masutani M, Yoshioka KI
- Journal Title
  
  J Biol Chem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] Complexity of cancer stem cells.2013
- Author(s)
  Sugihara E, Saya H.
- Journal Title
  
  Int J Cancer.
  
  Volume: 132(6): Issue: 6 Pages: 1249-1259
- DOI
  10.1002/ijc.27961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376, KAKENHI-PLANNED-22130007
[Journal Article] Twist2 functions as a tumor suppressor in murine osteosarcoma cells.2013
- Author(s)
  Ishikawa T, Shimizu T, Ueki A, Yamaguchi S, Onishi N, Sugihara E, Kuninaka S, Miyamoto T, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Mabuchi Y, Matsuzaki Y, Yamaguchi R, Miyano S and Saya H
- Journal Title
  
  Cancer Sci
  
  Volume: (in press) Issue: 7 Pages: 880-888
- DOI
  10.1111/cas.12163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-24590360, KAKENHI-PROJECT-24592244, KAKENHI-PROJECT-24659789, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245
[Journal Article] Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes.2013
- Author(s)
  Osawa T, Atsumi Y, Sugihara E, Saya H, Kanno M, Tashiro F, Masutani M, Yoshioka K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 432 Issue: 1 Pages: 34-39
- DOI
  10.1016/j.bbrc.2013.01.091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501271, KAKENHI-PROJECT-23790376
[Journal Article] xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma2013
- Author(s)
  Yoshikawa M, Tsuchihashi K, Ishimoto T, Yae T, Motohara T, Sugihara E, Onishi N, Masuko T, Yoshizawa K, Kawashiri S, Mukai M, Asoda S, Kawana H, Nakagawa T, Saya H, Nagano O
- Journal Title
  
  Cancer Res
  
  Volume: 73(6) Issue: 6 Pages: 1855-1866
- DOI
  10.1158/0008-5472.can-12-3609-t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592100, KAKENHI-PROJECT-23659941, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24592965, KAKENHI-PROJECT-24791713, KAKENHI-PROJECT-24792194, KAKENHI-PROJECT-25293344, KAKENHI-PROJECT-25870730, KAKENHI-PLANNED-22130007
[Journal Article] Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells2012
- Author(s)
  Mayumi Tamada, et al
- Journal Title
  
  Cancer Research
  
  Volume: 72 Issue: 6 Pages: 1438-1448
- DOI
  10.1158/0008-5472.can-11-3024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J55543, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-22700865, KAKENHI-PROJECT-22710222, KAKENHI-PROJECT-23790376
[Journal Article] Fibroblast growth factor-2 (Fgf2) is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma.2012
- Author(s)
  Shimizu T, Ishikawa T, Iwai S, Ueki A, Sugihara E, Onishi N, Kuninaka S, Miyamoto T, Toyama Y, Ijiri H, Mori H, Matsuzaki Y, Yaguchi T, Nishio H, Kawakami Y, Ikeda Y and Saya H
- Journal Title
  
  Mol Cancer Res
  
  Volume: 10(3) Pages: 454-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] 癌幹細胞研究の現状と将来2012
- Author(s)
  杉原英志, 佐谷秀行
- Journal Title
  
  血液内科
  
  Volume: 64 Pages: 120-126
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] 幹細胞研究の現状と将来2012
- Author(s)
  杉原英志、佐谷秀行
- Journal Title
  
  血液内科
  
  Volume: 64(1) Pages: 120-126
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells.2012
- Author(s)
  Tamada M, Nagano O, Tateyama S, Ohmura M, Yae T, Ishimoto T, Sugihara E, Onishi N, Yamamoto T, Yanagawa H, Suematsu M and Saya H
- Journal Title
  
  Cancer Res
  
  Volume: 72(6) Pages: 1438-1448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor2012
- Author(s)
  Sugihara E, Saya H, et al
- Journal Title
  
  Oncogene
  
  Volume: (印刷中) Issue: 23 Pages: 2849-2861
- DOI
  10.1038/onc.2011.462
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-22700865, KAKENHI-PROJECT-23590350, KAKENHI-PROJECT-23616003, KAKENHI-PROJECT-23790376
[Journal Article] Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer2012
- Author(s)
  Arima Y, Saya H, et al
- Journal Title
  
  InternationalJournal of Cancer
  
  Volume: 130 Issue: 11 Pages: 2568-2579
- DOI
  10.1002/ijc.26271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650601, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-23791496
[Journal Article] Fibroblast Growth Factor-2 Is an Important Factor that Maintains Cellular Immaturity and Contributes to Aggressiveness of Osteosarcoma2012
- Author(s)
  Shimizu T., et al
- Journal Title
  
  Mol Cancer Res
  
  Volume: 10(3) Issue: 3 Pages: 454-468
- DOI
  10.1158/1541-7786.mcr-11-0347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06969, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-22241052, KAKENHI-PROJECT-22700865, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-23791293, KAKENHI-PROJECT-24590360
[Journal Article] Up-regulation of imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.2012
- Author(s)
  Ueki A, Shimizu T, Masuda K, Yamaguchi SI, Ishikawa T, Sugihara E, Onishi N, Kuninaka S, Miyoshi K, Muto A, Toyama Y, Banno K, Aoki D, Saya H.
- Journal Title
  
  PLoS One
  
  Volume: 7(11) Issue: 11 Pages: e50621-e50621
- DOI
  10.1371/journal.pone.0050621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24501320, KAKENHI-PLANNED-22130007
[Journal Article] Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells2011
- Author(s)
  Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Osuka A, Akahata M, Kai K, Sugimoto H, Hirao A, and Saya H
- Journal Title
  
  Neoplasia
  
  Volume: 13(9) Pages: 784-791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] Establishment of a Choriocarcinoma Model from Immortalized Normal Extravillous Trophoblast Cells Transduced with HRASV122011
- Author(s)
  Kobayashi Y, Shimizu T, Naoe H, Ueki A, Ishizawa J, Chiyoda T, Onishi N, Sugihara E, Nagano O, Banno K, Kuninaka S, Aoki D, Saya H
- Journal Title
  
  Am J Pathol.
  
  Volume: 179(3) Issue: 3 Pages: 1471-82
- DOI
  10.1016/j.ajpath.2011.05.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells.2011
- Author(s)
  Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Osuka A, Akahata M, Kai K, Sugimoto H, Hirao A, and Saya H
- Journal Title
  
  Neoplasia
  
  Volume: 13(9) Pages: 784-791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] Establishment of a Choriocarcinoma Model from Immortalized Normal Extravillous Trophoblast Cells Transduced with HRASV122011
- Author(s)
  Kobayashi Y, Shimizu T, Naoe H, Ueki A, Ishizawa J, Chiyoda T, Onishi N, Sugihara E, Nagano O, Banno K, Kuninaka S, Aoki D, Saya H
- Journal Title
  
  Am J Pathol
  
  Volume: 179(3) Pages: 1471-1482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376
[Journal Article] The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic stem cells and mature lineage progenitors by protecting from genotoxic stress2011
- Author(s)
  Ishizawa, J.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 5 Pages: 967-974
- DOI
  10.1111/j.1349-7006.2011.01884.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23790376
[Presentation] 新規マウスモデルを用いた高異型度漿液性癌の予後不良に関連するバイオマーカーの同定2023
- Author(s)
  今枝慶蓉, 増田健太, 永井晋平, 田村友宏, 杉原英志, 山崎淳太郎, 大槻雄士, 信末博行, 千代田達幸, 小林佑介, 阪埜浩司, 青木大輔, 山上亘, 佐谷秀行, 永野修.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07179
[Presentation] In-house CGPの臨床的意義:若年性前立腺癌の発生と予後に関連する病的バリアント2023
- Author(s)
  住友誠, 竹田真由, 杉原英志, 塚本徹哉, 佐谷秀行
- Organizer
  日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07179
[Presentation] がんゲノム診断がん遺伝子パネル検査を用いた髄膜腫の解析.2023
- Author(s)
  大場茂生, 杉原英志, 山田勢至, 中江俊介, 西山悠也, 武藤淳, 安達一英, 安部雅人, 佐谷秀行, 廣瀬雄一
- Organizer
  日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-22K07179
[Presentation] Elucidation of the mechanisms of tumorigenesis in intracranial germ cell tumor by whole genome sequence2020
- Author(s)
  Yuki Yamagishi, Hirokazu Takami, Daichi Narushima, Yuko Matsushita, Eiji Sugihara, Ryo Nishikawa, Mamoru Kato and Koichi Ichimura
- Organizer
  The 19th International Symposium on Pediatric Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03440
[Presentation] BRD4 regulates Livin expression and thereby confers resistance to Fas-mediated immune cytotoxity in aggressive B cell lymphoma.2019
- Author(s)
  2.Sugihara E, Hashimoto N, Osuka S, Ueno S, Shimizu T, Okamoto S, Saya H.
- Organizer
  AACR annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07224
[Presentation] Mycをドライバーとする発がん誘導モデルの構築と応用2018
- Author(s)
  杉原　英志、佐谷秀行
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07224
[Presentation] Livin confers the resistance to lymphoma-suppressive barrier by Fas restoration2017
- Author(s)
  Sugihara E, Hashimoto N, Osuka S, Ueno S, Shimizu T, Okamoto S, Saya H.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06840
[Presentation] Development of a new mouse model for mature B cell lymphoma and resistance to Fas restoration-triggered apoptosis.2016
- Author(s)
  Sugihara E, Hashimoto N, Osuka S, Ueno S, Shimizu T, Okamoto S, Saya H.
- Organizer
  The 58st annual meeting of American Society of Hematology
- Place of Presentation
  サンディエゴ、アメリカ
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06840
[Presentation] Targeting Livin with Fas-signal restoration is a potential therapy for Non-Hodgkin Lymphomas2016
- Author(s)
  Sugihara E, Hashimoto N, Osuka S, Ueno S, Shimizu T, Okamoto S, Saya H.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-15K06840
[Presentation] New mouse model for mature B cell lymphoma revealing requirement for Fas downregulation in lymphomagenesis.2015
- Author(s)
  Sugihara E, Hashimoto N, Ueno S, Saya H.
- Organizer
  ヨーロッパ血液学会 EHA
- Place of Presentation
  ウィーン、オーストリア
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06840
[Presentation] New mouse lymphoma model reveals the requirement for Fas downregulation in initiation and maintenance of lymphoma cells2015
- Author(s)
  杉原英志、橋本典愉、植野さやか、清水孝恒、佐谷秀行
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K14384
[Presentation] New mouse model for mature B cell lymphoma revealing requirement for Fas downregulation in lymphomagenesis.2015
- Author(s)
  Sugihara E, Hashimoto N, Ueno S, Saya H
- Organizer
  20th Congress of European Hematology Association
- Place of Presentation
  Vienna, Austria.
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14384
[Presentation] Novel mouse model for mature B cell lymphoma reveals the requirement for Fas downregulation in lymphomagenesis.2015
- Author(s)
  Sugihara E, Hashimoto N, Ueno S, Saya H
- Organizer
  American Association for Cancer Research Annual meeting
- Place of Presentation
  Philadelphia, USA.
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14384
[Presentation] New mouse lymphoma model reveals the requirement for Fas downregulation in initiation and maintenance of lymphoma cells2015
- Author(s)
  Sugihara E, Hashimoto N, Ueno S, Shimizu T, Saya H.
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06840
[Presentation] Novel mouse model for mature B cell lymphoma reveals the requirement for Fas downregulation in lymphomagenesis.2015
- Author(s)
  Sugihara E, Hashimoto N, Ueno S, Saya H.
- Organizer
  米国癌学会 AACR
- Place of Presentation
  フィラデルフィア、米国
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06840
[Presentation] Establishment of simple and rapid Burkitt lymphoma model2013
- Author(s)
  Hashimoto N, Sugihara E, Saya H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860245
[Presentation] Cancer stem-like cells in mouse B-ALL model show the quiescent state, glycolytic gene expression and plasticity2013
- Author(s)
  Sugihara E, Shimizu T, Mogushi K, Hashimoto N, Saya H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860245
[Presentation] Identification and characterization of cancer stem like chemotherapeutic resistant cells in mouse pre-B ALL model2012
- Author(s)
  Sugihara E, Saya H
- Organizer
  日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Tumor cells derived from different cells of origin show distinct therapeutic sensitivities in Mycinducedlymphoid tumor model2012
- Author(s)
  Sugihara E, Saya H
- Organizer
  Annual meeting of American Society for Cell Biology (ASCB)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Identification and characterization of cancer stem like chemotherapeutic resistant cells in mouse pre-B ALL model2012
- Author(s)
  Sugihara E, Hashimoto N, Saya H
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] umor cells derived from different cells of origin show distinct therapeutic sensitivities in Myc-induced lymphoid tumor model2012
- Author(s)
  Sugihara E, Saya H.
- Organizer
  American Society of Cell Biology
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Arf and Ink4a are critical factors detemining the cell of origin and therapeutic of Myc-induced mouse lymphoid tumor2011
- Author(s)
  Sugihara E, Kojima K, Ishizawa J, Micheal A, Saya H
- Organizer
  The 53rd annual meeting of American Society of Hematology (ASH)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Ink4a and Arf determine the cell of origin and therapeutic sensitivity of Myc-induced lymphoid tumor2011
- Author(s)
  Sugihara E, Shimizu T, Ishizawa J, Saya H
- Organizer
  第67回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Arf and Ink4a are critical factors detemining the cell of origin and therapeutic of Myc-induced mouse lymphoid tumor2011
- Author(s)
  Sugihara E, Kojima K, Ishizawa J, Andreeff M, Saya H
- Organizer
  第53回アメリカ血液学会総会
- Place of Presentation
  米国サンディエゴ国際会議場
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Ink4a and Arf determine the cell of origin and therapeutic sensitivity of Myc-induced lymphoid tumor2011
- Author(s)
  Sugihara E、Shimizu T, Ishizawa J, Saya H
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790376
[Presentation] Characterization of leukemic stem-like cells with drug resistance and plasticity in B-ALL model
- Author(s)
  Sugihara E、Shimizu T, Mogushi K, Hashimoto N, Saya H
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25860245

1. Saya Hideyuki (80264282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. Yamano Shotaro (80614528)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 七野成之 (70822435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ICHIMURA KOICHI (40231146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. Tomita Akihiro (80378215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 加藤護 (40391916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 小島洋児 (70720811)

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# of Collaborated Products: 0 results
8. 安田貴彦 (20723977)

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9. 鈴木絢子 (00770348)

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10. 増田健太 (30773460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 高須正規 (00503327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 新井佐知子 (10409831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山本雄介 (60768117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 風間啓 (80845298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. UEHA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SHIMIZU Takatsune

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. YOSHIDA Kazunari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. ONISHI Nobuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. TASHIRO Fumio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. ASODA Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. YOSHIKAWA Momoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 信末博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 北畠正大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 本津茂人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 市原寿子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 岡崎章悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 神田輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 小島研介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 戸田正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugihara Eiji 杉原 英志

SUGIHARA Eiji 杉原 英志

Research Projects

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Generation of pneumoconiosis atlas unraveling at 1-cell resolution

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The role of MYC in treatment resistance of acute myeloid leukemiaPrincipal Investigator

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Elucidation of the molecular basis of MYC-driven cancers and development of therapeutic strategiesPrincipal Investigator

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Evaluation of minimal residual disease by liquid biopsy in malignant lymphoma for precise therapeutic stratification.

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Comprehensive Fundamental Research on the Onset and Development of Pneumoconiosis Using TAS-Seq

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A comprehensive genomic analysis of central nervous system germ cell tumors and generation of their cellular model

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Integrated elucidation and control of malignant mechanism in MYC-induced lymphomaPrincipal Investigator

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Elucidation of molecular mechanism of immune evasion in malignant lymphomaPrincipal Investigator

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Analysis of escaping mechanism from immune system by microenvironment of cancer stem cells

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Analysis of mature B cell lymphomagenes by mutated epigenetic factorsPrincipal Investigator

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Analysis of CD44 role in metabolism of leukemic stem cellPrincipal Investigator

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[Journal Article] In utero tumor development and identification of <i>CTNNB1</i> mutation in a newborn case of ossifying renal tumor of infancy2024

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[Journal Article] Clinical application of long‐read nanopore sequencing in a?preimplantation genetic testing pre‐clinical workup to identify the junction for complex Xq chromosome rearrangement‐related disease2023

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Sugihara Eiji 杉原英志

SUGIHARA Eiji 杉原英志

[Journal Article] 特集がん遺伝子の発見は現代医療を進歩させたか Ⅰ.がん遺伝子研究の新しい展開がん悪性形質をつかさどるMYCの新機能と制御2023