Kim Minsoo ＫｉｍＭｉｎｓｏｏ

… Alternative Names

KIM Minsoo KIM Minsoo

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Researcher Number	50466835
Other IDs	https://orcid.org/0000-0001-8536-8653
Affiliation (Current)	2024: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 京都大学, 医学研究科, 准教授 2020: 京都大学, 医学研究科, 特定准教授 2015 – 2019: 京都大学, 白眉センター, 特定准教授 2012 – 2014: 東京大学, 医科学研究所, 特任准教授 2011: 東京大学, 医科学研究所, 特任助教 2008 – 2009: The University of Tokyo, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Bacteriology (including Mycology) / Bacteriology (including Mycology) / Basic Section 37030:Chemical biology-related / Experimental pathology Except Principal Investigator Structural biochemistry / Basic Section 56010:Neurosurgery-related / Basic Section 43020:Structural biochemistry-related
Keywords	Principal Investigator エフェクター / 病原細菌 / 感染制御 / ユビキチン / ケミカルバイオロジー / 抗菌剤 / 細菌感染 / 感染症 / 病原細菌感染 / 炎症 … More / 赤痢菌 / 細胞運動 / 蛋白質分解 / 蛋白質 / X-線構造 / エフェクタ- / 阻害剤 / 病原性大腸菌 / 細胞周期 / 感染免疫 … More Except Principal Investigator 蛋白質 / エフェクター / 細菌 / X線結晶構造解析 / 赤痢菌 / 細胞内シグナル / 血管閉塞 / 血管閉塞性疾患 / RNF213 / シグナル伝達 / もやもや病 / ユビキチン / 構造解析 / Ｘ線結晶構造解析 / IpaH / ユビキチンリガーゼ / ユビキチン修飾経路 / OspI / 複合体構造 / エフェクタータンパク質 / ユビキチン経路 Less

International collaboration for the development of new molecular-targeted antimicrobial agentsPrincipal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyoto University
細菌感染に対して有効な宿主免疫賦活化薬剤の創出Principal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyoto University
病原因子の分解を誘導する分子標的型新規抗菌剤の開発基盤の構築Principal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto University
病原細菌エフェクターによるNF-κB経路を標的とした感染機構の解析
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  University of Hyogo
Functional analysis of heritable risk factors for moyamoya disease and stroke
- Principal Investigator
  
  Tezuka Tohru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Bacteria Hijack host ubiquitin systemPrincipal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
バクテリアが持つユビキチン修飾システムPrincipal Investigator
- Principal Investigator
  
  Kim Minsoo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infection
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
バクテリアが利用するユビキチンシステムPrincipal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
細菌病原因子と宿主標的蛋白質の相互作用基盤Principal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
病原細菌感染における宿主細胞の免疫応答解明Principal Investigator
- Principal Investigator
  
  芦田浩, KIM Minsoo, 金玟秀
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Structural analyses of bacterial effectors and their mechanisms of infection
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
Development of new therapeutic tools against pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Analysis of host cell cycle arrest mechanism by EPEC infectionPrincipal Investigator
- Principal Investigator
  
  KIM Minsoo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo

[Book] Cbl proteins2008
- Author(s)
  Tezuka T, Kim M, Yamamoto T
- Publisher
  NOVA publishers
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] Structural insight into the recognition of the linear ubiquitin assembly complex by <i>Shigella</i> E3 ligase IpaH1.4/2.52023
- Author(s)
  Hiragi Keito、Nishide Akira、Takagi Kenji、Iwai Kazuhiro、Kim Minsoo、Mizushima Tsunehiro
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 4 Pages: 317-326
- DOI
  10.1093/jb/mvac109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20H03198, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499
[Journal Article] Active site structure of the <i>Shigella flexneri</i> effector OspI2022
- Author(s)
  Nishide Akira、Takagi Kenji、Kim Minsoo、Mizushima Tsunehiro
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.02.15.480433
- Open Access
- Data Source
  KAKENHI-PROJECT-18K14637, KAKENHI-PROJECT-20H03198
[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFκB activation and apoptosis in an AAA+ domain-dependent manner2020
- Author(s)
  Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Issue: 3 Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-20H03790
[Journal Article] Hijacking of the host ubiquitin system by pathogenic bacteria2020
- Author(s)
  西出旭、KIM MINSOO
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 75-83
- DOI
  10.14952/SEIKAGAKU.2020.920075
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K15750, KAKENHI-PROJECT-17K08786
[Journal Article] Microglia-triggered plasticity of intrinsic excitability modulates psychomotor behaviors in acute cerebellar inflammation2019
- Author(s)
  Yamamoto M, Kim M, Imai H, Itakura Y, Ohtsuki G
- Journal Title
  
  Cell Rep
  
  Volume: 28 Issue: 11 Pages: 2923-2938
- DOI
  10.1016/j.celrep.2019.07.078
- NAID
  120006719354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08786
[Journal Article] Manipulation of host ubiquitin-proteasome system by bacterial pathogens2017
- Author(s)
  Kim Minsoo
- Journal Title
  
  Journal of The Society of Japanese Women Scientists
  
  Volume: 17 Issue: 1 Pages: 8-18
- DOI
  10.5939/sjws.17002
- NAID
  130005465162
- ISSN
  1349-4449, 2186-3776
- Language
  Japanese
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Journal Article] バクテリアの病原性とユビキチン関連修飾システム2016
- Author(s)
  M KIM
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 (8) Pages: 880-884
- Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Journal Article] Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.82016
- Author(s)
  K Takagi, et al
- Journal Title
  
  Acta Cryst
  
  Volume: F72 Issue: 4 Pages: 269-275
- DOI
  10.1107/s2053230x16002715
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01174, KAKENHI-PROJECT-15H04341, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-16K14700
[Journal Article] Bacterial Effectors and Their Functions in the Ubiquitin-Proteasome System: Insight from the Modes of Substrate Recognition2014
- Author(s)
  Kim M et. al
- Journal Title
  
  Cells
  
  Volume: 3 Issue: 3 Pages: 848-864
- DOI
  10.3390/cells3030848
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-14J10879, KAKENHI-PROJECT-23000012, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
[Journal Article] The Shigella OspC3 effector inhibits Cspase-4, antagonizes inflammatory cell death, and promotes epithelial infection2013
- Author(s)
  Kobayashi T, et. al
- Journal Title
  
  Cell Host Microbe
  
  Volume: 13 Issue: 5 Pages: 570-583
- DOI
  10.1016/j.chom.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PUBLICLY-24117507, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555
[Journal Article] Structural basis for the recognition of Ubcl3 by the Shigella flexneri effector OspI.2013
- Author(s)
  Nishide A, Kim M, Takagi K, Himeno A, Sanada T, Sasakawa C, Mizushima T.
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370049
[Journal Article] Structural basis for the recognition of Ubcl3 by the Shigell a flexneri effector OspI2013
- Author(s)
  Nishide A, et. al
- Journal Title
  
  J Mol Bio.
  
  Volume: 425 Issue: 15 Pages: 2623-2631
- DOI
  10.1016/j.jmb.2013.02.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23689027, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
[Journal Article] 病原性バクテリアによるユビキチン修飾系の制御2012
- Author(s)
  Kim Minsoo
- Journal Title
  
  医学のあゆみ
  
  Volume: 243 Pages: 535-540
- Data Source
  KAKENHI-PROJECT-23689027
[Journal Article] p130Cas-dependent actin remodeling regulates myogenic differentiation2012
- Author(s)
  Kawauchi K, Tan WW, Araki K, Bakar F, Kim M, Fujita H, Hirata H, Sawada Y
- Journal Title
  
  Biochemical Journal
  
  Volume: 445(3) Issue: 3 Pages: 323-332
- DOI
  10.1042/bj20112169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-24570191
[Journal Article] Shigella targets epithelial tricellular junctions to spread between cells via a noncanonical clathrin-dependent endocytic pathway.2012
- Author(s)
  Makoto Fukumatsu
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 11 Issue: 4 Pages: 325-336
- DOI
  10.1016/j.chom.2012.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-22390013, KAKENHI-PROJECT-22770054, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23657084, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-24117507, KAKENHI-PUBLICLY-24121708
[Journal Article] Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c.2012
- Author(s)
  Takesita K
- Journal Title
  
  J. Biochem.
  
  Volume: 152 Issue: 5 Pages: 487-495
- DOI
  10.1093/jb/mvs085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227003, KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-22370041, KAKENHI-PROJECT-23249013, KAKENHI-PROJECT-23689027, KAKENHI-PLANNED-22121006, KAKENHI-PUBLICLY-23121506, KAKENHI-PUBLICLY-24121705
[Journal Article] The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response2012
- Author(s)
  Sanada, T.
- Journal Title
  
  Nature
  
  Volume: 483 Issue: 7391 Pages: 623-626
- DOI
  10.1038/nature10894
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117002, KAKENHI-PROJECT-22790403, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23770203, KAKENHI-PROJECT-23790471
[Journal Article] Monoubiquitination of Tob/BTG family proteins competes with degradation-targeting polyubiquitination.2011
- Author(s)
  Suzuki T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 409 Issue: 1 Pages: 70-4
- DOI
  10.1016/j.bbrc.2011.04.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-21360398, KAKENHI-PUBLICLY-23121506, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-23689027
[Journal Article] Bacteria and host interactions in the gut epithelial barrier2011
- Author(s)
  Ashida H., Sasakawa C., et al.
- Journal Title
  
  Nat Chem Biol
  
  Volume: 8 Issue: 1 Pages: 36-45
- DOI
  10.1038/nchembio.741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471
[Journal Article] Cell death and infection : a double-edged sword for host and pathogen survival2011
- Author(s)
  Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, Sasakawa C
- Journal Title
  
  J Cell Biol
  
  Volume: 195 Issue: 6 Pages: 931-942
- DOI
  10.1083/jcb.201108081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23659220, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471
[Journal Article] Coronin7 forms a novel E2 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob2011
- Author(s)
  Watanabe M, Suzuki T, Kim M, Abe Y, Yoshida Y, Sugano S, Yamamoto T
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Pages: 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689027
[Journal Article] Bacterial hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment2009
- Author(s)
  Kim M, Ogawa M, Fujita Y, Yoshikawa Y, Nagai T, Koyama T, Nagai S, Lange A, Fassler R, Sasakawa C
- Journal Title
  
  Nature 459
  
  Pages: 578-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] Bacterial hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment2009
- Author(s)
  Kim, et al.
- Journal Title
  
  Nature 459
  
  Pages: 578-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] Listeria monocytogenes ActA-mediated escape from autophagic recognition2009
- Author(s)
  Yoshikawa Y, Ogawa M, Hain T, Yoshida M, Fukumatsu M, Kim Minsoo, Mimuro H, Nakagawa I, Yanagawa T, Ishii T, Kakizuka A, Sztul E, Chakraborty T, Sasakawa C
- Journal Title
  
  Nature Cell biology 11(19)
  
  Pages: 1233-1240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] A new ubiquitin ligase involved in p57^<KIP2> proteolysis regulates osteoblast cell differentiation2008
- Author(s)
  Minsoo Kim et.al.
- Journal Title
  
  EMBO reports 9
  
  Pages: 878-884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790330
[Journal Article] A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation2008
- Author(s)
  Kim M, Nakamoto T, Nishimori S, Tanaka K, Chiba T
- Journal Title
  
  EMBO reports 9
  
  Pages: 878-884
- Data Source
  KAKENHI-PROJECT-20790330
[Presentation] X線結晶構造解析による赤痢菌エフェクターIpaH1.4/2.5のLUBAC阻害機構の解析2022
- Author(s)
  平木慶人・西出旭・高木賢治・Kim Minsoo・水島恒裕
- Organizer
  令和4年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5基質認識ドメインの構造及び基質認識機構の解析2022
- Author(s)
  平木慶人・西出旭・高木賢治・Kim Minsoo・水島恒裕
- Organizer
  第5回　バイオダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5のX線結晶構造解析および機能解析2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第67回　日本生化学会　近畿支部例会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクター IpaH1.4/2.5 による直鎖状ポリユビキチン鎖生成酵素 (LUBAC) 認識機構の解析2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第21回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5によるLUBAC複合体認識機構の解明2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第4回ピコバイオロジー研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Ｘ線結晶構造解析による赤痢菌エフェクターIpaH1.4及び2.5の基質認識機構の解析2020
- Author(s)
  平木慶人、西出旭、高木賢治、Kim Minsoo、水島恒裕
- Organizer
  日本結晶会　令和2年度年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Post-translational modification of Ubc13 during bacterial infection2019
- Author(s)
  Takagi K, Nishide A, Inoue J, Iwai K, Mizushima T, Kim Minsoo
- Organizer
  EMBO workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチン修飾システムの相互作用基盤解析2019
- Author(s)
  高木賢治、西出旭、水島恒裕、Kim Minsoo
- Organizer
  第14回日本ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチンの翻訳後修飾解析2018
- Author(s)
  佐藤里紗、西出旭、永井明日香、Kim Minsoo
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] Regulation of host homeostasis by pathogenic bacterial ubiquitin ligases2018
- Author(s)
  Kim Minsoo
- Organizer
  JCUP-Ⅸ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチン修飾システムの相互作用基盤解析2018
- Author(s)
  Kim Minsoo、高木賢治、水島恒裕
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] 脱アミド化型ユビキチンの構造解析2018
- Author(s)
  西出旭、水島恒裕、Kim Minsoo
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K08786
[Presentation] ユビキチン修飾システムの認識機構解明2017
- Author(s)
  Kim Minsoo
- Organizer
  日本女性科学者の会第11回学術大会
- Place of Presentation
  大阪科学技術センター
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2016
- Author(s)
  西出旭， Kim Minsoo, 高木賢治, 古田徹郎, 笹川千尋, 水島恒裕
- Organizer
  第16回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターOspIによるTRAF6阻害機構の構造生物学解析2016
- Author(s)
  高木賢治, 西出旭, Kim Minsoo, 笹川千尋, 水島恒裕
- Organizer
  新学術領域「ユビキチンネオバイオロジー」領域班会議
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 構造学的手法を用いた赤痢菌エフェクター IpaH ファミリーの反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 桑原直之, 加藤龍一, 笹川千尋, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] リアルタイムでユビキチン化を測定する方法の開発2016
- Author(s)
  Kim Minsoo
- Organizer
  第39　回　日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2016
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR.2016
- Author(s)
  Takagi, K., Kim, M., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクター IpaH1880 反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 水島恒裕
- Organizer
  新学術領域「ユビキチンネオバイオロジー」領域班会議
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターIpaH9.8によるNEMO認識機構の解析2016
- Author(s)
  高木賢治, 大津彩織, Kim Minsoo, 水島恒裕
- Organizer
  第16回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2015
- Author(s)
  西出旭，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Regulating host immune responses with bacterial effectors2015
- Author(s)
  Minsoo Kim
- Organizer
  3rd International Picobiology Institute Symposium
- Place of Presentation
  兵庫県立大学
- Year and Date
  2015-12-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01174
[Presentation] 赤痢菌エフェクタータンパク質IpaH9.8によるNEMOの認識機構の解析2015
- Author(s)
  大津彩織，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのＸ線結晶構造解析2015
- Author(s)
  高木賢治、Kim Minsoo、水島恒裕
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール(徳島・徳島市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural analysis of the recognition mechanism of NEMO by shigella effector IpaH9.82015
- Author(s)
  Otsu, S., Takagi, K., Kim, M., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR2015
- Author(s)
  Takagi, K., Kim, M.., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2015
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014
- Author(s)
  Kim M et.al
- Organizer
  International Union of Microbiological Societies Congresses 2014
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] Pathogenic bacteria interactions with the host epithelium2014
- Author(s)
  Kim M et.al
- Organizer
  The 22nd Federation meeting of Korean basic medical scientists
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014
- Author(s)
  Kim M et.al
- Organizer
  International Union of Microbiological Societies Congresses 2014
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] Pathogenic bacteria interactions with the host epithelium2014
- Author(s)
  Kim minsoo
- Organizer
  The 22nd Federation meeting of Korean basic medical scientists
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014
- Author(s)
  Kim M et.al
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014
- Author(s)
  Kim M et.al
- Organizer
  International Union of Microbiological Societies Congresses 2014
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014
- Author(s)
  Kim M et.al
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] Pathogenic bacteria interactions with the host epithelium2014
- Author(s)
  Kim minsoo
- Organizer
  The 22nd Federation meeting of Korean basic medical scientists
- Place of Presentation
  Seoul,Korea
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014
- Author(s)
  Kim M et.al
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] Real-time, lable-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase2013
- Author(s)
  金玟秀
- Organizer
  The 35^<th> Naito conference
- Place of Presentation
  札幌、日本
- Year and Date
  2013-07-10
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] OspI-Ubc13複合体構造解析による赤痢菌エフェクタータンパク質のE2酵素認識機構2013
- Author(s)
  西出旭、Minsoo Kim、高木賢治、真田貴人、笹川千尋、水島恒裕
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館 (鳥取)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 脱アミド化Ubc13の構造解析による赤痢菌感染機構の考察2013
- Author(s)
  高木賢治　西出旭、Kim Minsoo、笹川千尋、水島恒裕
- Organizer
  新学術領域『ユビキチンネオバイオロジー』第2回領域会議
- Place of Presentation
  熱海ﾆｭｰﾌｼﾞﾔﾎﾃﾙ (静岡)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI2013
- Author(s)
  Nishide A., Kim M., Takagi K., Himeno A., Sanada T., Sasakawa C., Mizushima T.
- Organizer
  The 35th Naito Conference
- Place of Presentation
  ｼｬﾄﾚｰｾﾞｶﾞﾄｰｷﾝｸﾞﾀﾞﾑ(北海道)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 赤痢菌エフェクタータンパク質OspI-Ubc13複合体結晶構造解析による機能解析2013
- Author(s)
  西出旭,Minsoo Kim,高木賢治,真田真人,笹川千尋,水島恒裕
- Organizer
  新学術領域『ユビキチンネオバイオロジー』第2回領域会議
- Place of Presentation
  熱海ﾆｭｰﾌｼﾞﾔﾎﾃﾙ (静岡)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 赤痢菌エフェクタータンパク質OspI 活性中心の構造解析2012
- Author(s)
  西出旭、高木賢治、Minsoo Kim、真田貴人、笹川千尋、水島恒裕
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 病原細菌感染における宿主翻訳後修飾2012
- Author(s)
  金玟秀
- Organizer
  日本生化学学会大会
- Place of Presentation
  福岡、日本
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Regulation of host cell-cycle progression by bacterial pathogens2011
- Author(s)
  Kim Minsoo
- Organizer
  Ubiquitin Drug Discovery & diagnostics 2011
- Place of Presentation
  Philadelphia, U.S.A
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Regulation of host cell-cycle progression by bacterial pathogens2011
- Author(s)
  金玟秀
- Organizer
  Uiquitin Drug Discovery & diagnostics 2011
- Place of Presentation
  Philadelphia,米国
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] 細菌エフェクターOspEとインテグリンリンクドキナーゼの結合による感染細胞の剥離抑制機構2009
- Author(s)
  金〓秀
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20790330
[Presentation] 赤痢菌のエフェクターによる腸管上皮細胞のターンオーバー抑制2008
- Author(s)
  金〓秀
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20790330
[Presentation] Real-time, label-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase
- Author(s)
  Minsoo Kim
- Organizer
  The 35th Naito Conference
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25112506
[Presentation] 病原細菌感染における宿主翻訳後修飾
- Author(s)
  Kim Minsoo
- Organizer
  日本生化学学会大会
- Place of Presentation
  福岡・日本
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Real-time, label-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase
- Author(s)
  Minsoo Kim
- Organizer
  The 35th Naito Conference
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25121711
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research
- Place of Presentation
  国際高等研究所（京都・木津川市）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Real-time, label-free monitoring of poly ubiquitin chain formation with bacterial ubiquitin ligase
- Author(s)
  Minsoo Kim
- Organizer
  The 35th Naito Conference
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23689027
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PROJECT-24370049

1. MIZUSHIMA TSUNEHIRO (90362269)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
2. LEE JIHYE

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Tezuka Tohru (50312319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山吉麻子 (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Raudzus Fabian (10906358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 林剛介 (40648268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 西出旭 (80807652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 谷一寿 (20541204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. S Youssefian (00210576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 芦田浩 (10535115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 金玟秀

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOBAYASHI Hatasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 高木賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 笹川千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岩井一宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小泉昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 小川道永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 三室仁美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kim Minsoo Ｋｉｍ Ｍｉｎｓｏｏ

KIM Minsoo KIM Minsoo

Research Projects

Research Products

Co-Researchers

International collaboration for the development of new molecular-targeted antimicrobial agentsPrincipal Investigator

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細菌感染に対して有効な宿主免疫賦活化薬剤の創出Principal Investigator

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病原因子の分解を誘導する分子標的型新規抗菌剤の開発基盤の構築Principal Investigator

Principal Investigator

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病原細菌エフェクターによるNF-κB経路を標的とした感染機構の解析

Principal Investigator

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Functional analysis of heritable risk factors for moyamoya disease and stroke

Principal Investigator

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Review Section

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Bacteria Hijack host ubiquitin systemPrincipal Investigator

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バクテリアが持つユビキチン修飾システムPrincipal Investigator

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Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infection

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バクテリアが利用するユビキチンシステムPrincipal Investigator

Principal Investigator

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細菌病原因子と宿主標的蛋白質の相互作用基盤Principal Investigator

Principal Investigator

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Review Section

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病原細菌感染における宿主細胞の免疫応答解明Principal Investigator

Principal Investigator

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Structural analyses of bacterial effectors and their mechanisms of infection

Principal Investigator

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Development of new therapeutic tools against pathogenic bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Kim Minsoo ＫｉｍＭｉｎｓｏｏ