KAKUTA YOICHI 角田洋一

… Alternative Names

KAKUTA Yoichi 角田洋一

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Researcher Number	50509205
Other IDs	https://orcid.org/0000-0002-7042-009X
Affiliation (Current)	2025: 東北大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 東北大学, 医学系研究科, 講師 2013 – 2023: 東北大学, 大学病院, 助教 2011 – 2012: 東北大学, 医学(系)研究科(研究院), 非常勤講師 2010 – 2011: Tohoku University, 大学院・医学系研究科, 非常勤講師 2010: 東北大学, 医学系研究科, 非常勤講師 2009: Tohoku University, 病院, 医員 2008: 東北大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 炎症性腸疾患 / 潰瘍性大腸炎 / クローン病 / 感受性遺伝子 / 疾患感受性遺伝子 / 体細胞モザイク変異 / チオプリン製剤 / 染色体異常モザイク / 全ゲノムシーケンス解析 / 染色体変異モザイク … More / 染色体異常 / モザイク変異 / 消化器内科学 / 遺伝学 / 腸内細菌叢 / NKS2.3 / HLA-B52 / SLC26A3 / TNFSF15 … More Except Principal Investigator 炎症性腸疾患 / クローン病 / 潰瘍性大腸炎 / チオプリン / 疾患感受性遺伝子 / NUDT15 / 感受性遺伝子 / 細胞実験 / 薬物トランスポーター / CRISPR screening / コピー数多型 / Defensin / SOMAscan / 唾液バイオマーカー / プロテーム解析 / 診断機器 / プロテオーム解析 / 唾液 / 胎児 / NUDT15遺伝子多型 / 遺伝子変異 / タイトジャンクション / 単層培養 / RAP1A / オルガノイド / microRNA / エピゲネティクス / バイオマーカー / CXCR4 / MIR622 / エピジェネティクス / GWAS / MIR622遺伝子 / 薬物代謝酵素 / 薬理ゲノム / チオプリン製剤 / eQTL / アリル特異的DNAメチル化 / エピゲノム / NKX2.3 / 感受性遺云子 / allelic expression imbalance / TNFSF15 Less

CRISPRスクリーニングで紐解く炎症性腸疾患治療薬の作用と新規治療戦略
- Principal Investigator
  
  志賀永嗣
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Analysis of factors contributing to pathogenesis and severity of inflammatory bowel disease using comprehensive copy number estimation of the Defensin gene cluster
- Principal Investigator
  
  木内喜孝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
炎症性腸疾患患者のチオプリンに暴露された胎児の遺伝的選択・変異に関する検討
- Principal Investigator
  
  志賀永嗣
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
炎症性腸疾患の疾患活動度をモニターする唾液マーカーの探索
- Principal Investigator
  
  兼平正史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
Elucidation of the susceptibility mechanism for ulcerative colitis of MIR622 and exploration of its clinical application
- Principal Investigator
  
  Kinouchi Yoshitaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Functional analysis of disease susceptibility gene RAP1A using organoid monolayer from Crohn's Disease
- Principal Investigator
  
  Moroi RIntaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Analysis of the Onset and Pathological Changes of Crohn's Disease through Somatic Mosaicism Mediated by Genomic InstabilityPrincipal Investigator
- Principal Investigator
  
  Kakuta Yoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Development of a method for measuring the activity of the newly identified thiopurine metabolizing enzyme NUDT15
- Principal Investigator
  
  Shiga Hisashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
An integrated genomic and transcriptomic analysis to reveals susceptibility genes for Cronh's disease in Japanese populations
- Principal Investigator
  
  Kinouchi Yoshitaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Gene-microbiota interaction of inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  Kakuta Yoichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Genome-wide association study of inflammatory bowel disease using population optimized array and reference panel in JapanesePrincipal Investigator
- Principal Investigator
  
  Kakuta Yoichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Analysis of allele specific DNA methylation of the susceptibility genes to inflammatory bowel disease
- Principal Investigator
  
  KINOUCHI Yoshitaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
To determine a disease pathway related with NKX2.3 in inflammatory bowel disease
- Principal Investigator
  
  KINOUCHI Yoshitaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
日本人潰瘍性大腸炎感受性遺伝子SLC26A3の遺伝子多型機能解析Principal Investigator
- Principal Investigator
  
  角田洋一
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
TNFSF15 derived from T cells may play an important role in the pathogenesis of Crohn's disease.Principal Investigator
- Principal Investigator
  
  KAKUTA Yoichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Functional analyses of TNFSF15 as a susceptibility gene for Crohn's disease.
- Principal Investigator
  
  KINOUCHI Yoshitaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University

All 2023 2022 2020 2018 2017 2016 2015 2013 2011 2010 2009

All Journal Article Presentation

[Journal Article] Usefulness and difficulties with the thiopurine pharmacogenomic NUDT15 genotyping test: Analysis of real-world data in Japan2023
- Author(s)
  Kakuta Yoichi、Kato Motohiro、Shimoyama Yusuke、Naito Takeo、Moroi Rintaro、Kuroha Masatake、Shiga Hisashi、Kinouchi Yoshitaka、Masamune Atsushi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 153 Issue: 3 Pages: 161-169
- DOI
  10.1016/j.jphs.2023.09.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08024, KAKENHI-PROJECT-21K07955
[Journal Article] Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.2023
- Author(s)
  Liu Z, Liu R, Gao H, Jung S, Gao X, Sun R, Liu X, Kim Y, Lee HS, Kawai Y, Nagasaki M, Umeno J, Tokunaga K, Kinouchi Y, et al
- Journal Title
  
  Nat Genet.
  
  Volume: 55 Issue: 5 Pages: 796-806
- DOI
  10.1038/s41588-023-01384-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07884, KAKENHI-PROJECT-21K07955
[Journal Article] Crohn’s Disease and Early Exposure to Thiopurines are Independent Risk Factors for Mosaic Chromosomal Alterations in Patients with Inflammatory Bowel Diseases2022
- Author(s)
  Kakuta Y、Iwaki H、Umeno J、Kawai Y、Kawahara M、Takagawa T、Shimoyama Y、Naito T、Moroi R、Kuroha M、Shiga H、Watanabe K、Nakamura S、Nakase H、Sasaki M、Hanai H、Fuyuno Y、Hirano At、Matsumoto T、Kudo H、Minegishi N、Nakamura M、Hisamatsu T、Andoh A、Nagasaki M、Tokunaga K、Kinouchi Y、Masamune A
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 16 Issue: 4 Pages: 643-655
- DOI
  10.1093/ecco-jcc/jjab199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07955
[Journal Article] An Integrated Genomic and Transcriptomic Analysis Reveals Candidates of Susceptibility Genes for Crohn’s Disease in Japanese Populations2020
- Author(s)
  Kakuta Yoichi、Ichikawa Ryo、Fuyuno Yuta et al
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-020-66951-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07929
[Journal Article] Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease2018
- Author(s)
  Naito T, Yokoyama N, Kakuta Y, Ueno K, Kawai Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Nagasaki M, Masamune A, Kinouchi Y, Shimosegawa T
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 11 Pages: 1873-1881
- DOI
  10.1111/jgh.14149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04805
[Journal Article] Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease2018
- Author(s)
  Chiba Hirofumi、Kakuta Yoichi、Kinouchi Yoshitaka、Kawai Yosuke、Watanabe Kazuhiro、Nagao Munenori、Naito Takeo、Onodera Motoyuki、Moroi Rintaro、Kuroha Masatake、Kanazawa Yoshitake、Kimura Tomoya、Shiga Hisashi、Endo Katsuya、Negoro Kenichi、Nagasaki Masao、Unno Michiaki、Shimosegawa Tooru
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 3 Pages: e0194036-e0194036
- DOI
  10.1371/journal.pone.0194036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04805, KAKENHI-PROJECT-15K19311
[Journal Article] Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn’s disease is a risk factor for disease relapse in Japanese patients2017
- Author(s)
  Kakuta Yoichi、Kimura Tomoya、Negoro Kenichi、Kuroha Masatake、Shiga Hisashi、Endo Katsuya、Kinouchi Yoshitaka、Shimosegawa Tooru
- Journal Title
  
  J Gastroenterol
  
  Volume: 52 Issue: 12 Pages: 1230-1239
- DOI
  10.1007/s00535-017-1322-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04805
[Journal Article] LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients2017
- Author(s)
  Liu TC, Naito T, Liu Z, VanDussen KL, Haritunians T, Li D, Endo K, Kawai Y, Nagasaki M, Kinouchi Y, McGovern DP, Shimosegawa T, Kakuta Y, Stappenbeck TS
- Journal Title
  
  JCI Insight
  
  Volume: 印刷中 Issue: 6
- DOI
  10.1172/jci.insight.91917
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04805, KAKENHI-PROJECT-15K15284
[Journal Article] Involvement of NF-kappa B pathway in TL1A gene expression induced by lipopolysaccharide2010
- Author(s)
  Katsuya Endo, Yoshitaka Kinouchi, Yoichi Kakuta, Nobuo Ueki, Seiichi Takahashi, Tooru Shimosegawa
- Journal Title
  
  Cytokine 49
  
  Pages: 215-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790644
[Journal Article] 炎症性腸疾患への今日的アプローチ-病因・病態生理-遺伝子異常面からみた2010
- Author(s)
  角田洋一、木内喜孝、高橋成一、下瀬川徹
- Journal Title
  
  成人病と生活習慣病
  
  Volume: 40(12) Pages: 1351-1356
- Data Source
  KAKENHI-PROJECT-21790644
[Journal Article] 炎症性腸疾患への今日的アプローチ・病因・病態生理-遺伝子異常面からみた2010
- Author(s)
  角田洋一、木内喜孝、高橋成一、下瀬川徹
- Journal Title
  
  成人病と生活習慣病 Vol40 No12
  
  Pages: 1351-1356
- Data Source
  KAKENHI-PROJECT-21790644
[Journal Article] クローン病感受性遺伝子TNFSF15遺伝子多型における機能解析2009
- Author(s)
  角田洋一、木内喜孝、植木紳夫、遠藤克哉、根来健一、高橋成一、下瀬川徹
- Journal Title
  
  東北医学会雑誌 121
  
  Pages: 59-61
- NAID
  10026082877
- Data Source
  KAKENHI-PROJECT-21790644
[Journal Article] 消化器領域における遺伝子多型検査2009
- Author(s)
  角田洋一, 木内喜孝, 遠藤克哉, 根来健一, 高橋成一, 下瀬川徹
- Journal Title
  
  分子消化器病 6(4)
  
  Pages: 370-374
- Data Source
  KAKENHI-PROJECT-21790644
[Journal Article] TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells.2009
- Author(s)
  Kakuta Y, Ueki N, Kinouchi Y, Negoro K, Endo K, Nomura E, Takagi S, Takahashi S, Shimosegawa T.
- Journal Title
  
  Hum molecular Genetics 18(6)
  
  Pages: 1089-1098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590735
[Journal Article] HLA-B is the best candidate of susceptibility genes in HLA for Japanese ulcerative colitis.2009
- Author(s)
  Aizawa H, Kinouchi Y, Negoro K, Nomura E, Imai G, Takahashi S, Takagi S, Kakuta Y, Tosa M, Mochida A, Matsumura Y, Endo K, Shimosegawa T.
- Journal Title
  
  Tissue Antigens 73(6)
  
  Pages: 569-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590735
[Journal Article] TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells2009
- Author(s)
  Yoichi kakuta
- Journal Title
  
  Human molecular genetics 18
  
  Pages: 1089-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590735
[Presentation] 個人ゲノム情報から考えるIBD診療の将来像2017
- Author(s)
  角田洋一、木内喜孝、下瀬川徹
- Organizer
  第8回日本炎症性腸疾患学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04805
[Presentation] Population-optimized SNP array reveals RAP1A as a novel candidate susceptibility gene for Crohn’s disease in Japanese individuals2017
- Author(s)
  Yoichi Kakuta, Yosuke Kawai, Takeo Naito, Atsushi Hirano, Junji Umeno, Keiichiro Hiramoto, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura, Katsuya Endo, Yoshitaka Kinouchi, Motohiro Esaki, Masao Nagasaki, Tooru Shimosegawa
- Organizer
  Digestive Disease Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04805
[Presentation] 潰瘍性大腸炎患者における大腸部位別の腸内細菌叢と内視鏡的活動性との関係性について2017
- Author(s)
  角田洋一、横山直信、下瀬川徹
- Organizer
  第93回日本消化器内視鏡学会総会
- Place of Presentation
  大阪国際会議場、大阪
- Data Source
  KAKENHI-PROJECT-15K15284
[Presentation] Population-optimized SNP array reveals RAP1A as a novel candidate susceptibility gene for Crohn’s disease in Japanese individuals2017
- Author(s)
  Yoichi Kakuta, Yosuke Kawai, Takeo Naito, Atsushi Hirano, Junji Umeno, Keiichiro Hiramoto, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura1 Katsuya Endo, Yoshitaka Kinouchi, Motohiro Esaki, Masao Nagasaki, Tooru Shimosegawa
- Organizer
  Digestive Disease Week 2017
- Place of Presentation
  Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04805
[Presentation] ROR Alpha Gene may be Associated with Bone Mineral Density in Japanese Patients with Inflammatory Bowel Disease.2016
- Author(s)
  Naonobu Yokoyama, Yoichi Kakuta, Masatake Kuroha, Tomoya Kimura,Yositake Kanazawa, Katsuya Endo, Yoshitaka Kinouchi, Tooru Shimosegawa.
- Organizer
  The 4th Annual Meeting of Asian Organization for Crohns＆Colitis.
- Place of Presentation
  kyoto
- Year and Date
  2016-07-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460959
[Presentation] Paneth Cell Phenotype is Associated With Novel Genetic Determinants and Clinical Outcome in Japanese Crohn's Disease Patients2016
- Author(s)
  Takeo Naito, Ta-Chiang Liu, Yoichi Kakuta, Richard Head, Zhenqiu Liu, Talin Haritunians, Dalin Li, Katsuya Endo, Yoshitaka Kinouchi, Dermot McGovern, Thaddeus Stappenbeck, Tooru Shimosegawa
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04805
[Presentation] Paneth Cell Phenotype is Associated with Novel Genetic Determinants and Clinical Outcome in Japanese Crohn's Disease Patients2016
- Author(s)
  Takeo Naito, Ta-Chiang Liu, Yoichi Kakuta, Richard Head, Zhenqiu Liu, Talin Haritunians, Dalin Li, Katsuya Endo, Yoshitaka Kinouchi, Dermot P.B. McGovern, Thaddeus S. Stappenbeck, Tooru Shimosegawa
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15284
[Presentation] 人種最適化ジェノタイピングアレイによるゲノム解析から見えた日本人炎症性腸疾患の病因・病態にかかわる新たなDisease Pathway2015
- Author(s)
  ○角田洋一、木内喜孝、内藤健夫、黒羽正剛、木村智哉、遠藤克哉、下瀬川徹
- Organizer
  G-plus2015
- Place of Presentation
  ホテルイースト２１（東京）
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-15H04805
[Presentation] Autophagy is induced by ERstress mainly through IRE1alpha in human colon cancer cells and it plays a cytoprotective role.2013
- Author(s)
  Shimodaira Y, Takahashi S, Shiga H, Kakuta Y, Kinouchi Y, Shimosegawa T.
- Organizer
  21th United European Gastroenterology Week
- Place of Presentation
  ドイツ　ベルリン
- Data Source
  KAKENHI-PROJECT-23590932
[Presentation] Autophagy is induced by ERstress mainly through IRE1alpha in human colon cancer cells and it plays a cytoprotective role2013
- Author(s)
  Shimodaira Y, Takahashi S, Shiga H, Kakuta Y, Kinouchi Y, Shimosegawa T
- Organizer
  21th United European Gastroenterology Week
- Place of Presentation
  ドイツ・ベルリン
- Year and Date
  2013-10-14
- Data Source
  KAKENHI-PROJECT-23590932
[Presentation] Inhibition of autophagy by 3-MA enhances sodium butyrate-induced apoptosis in human colon cancer cells2011
- Author(s)
  Masatake Kuraha, Youichi Kakuta, Seiichi Takahashi, Yoshitaka Kinouchi, Tooru Shimosegawa
- Organizer
  19th United European Gastroenterology Week
- Place of Presentation
  ストックホルム(スウェーデン)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23790763
[Presentation] The IL12B gene is associated with the clinical course of Crohn's disease in Japanese patients.2010
- Author(s)
  Yoichi Kakuta, Yoshitaka Kinouchi, Hisashi Shiga, Katsuya Endo, Seiichi Takahashi, Tooru Shimosegawa
- Organizer
  18^<th> United European Gastroenterology Week
- Place of Presentation
  バルセロナ(スペイン)
- Year and Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-21790644
[Presentation] The IL12B ggene is associated with the clinical course of Crohn's disease in Japanese patients.2010
- Author(s)
  Kakuta Y
- Organizer
  18^<th> United European Gastroenterology Week
- Place of Presentation
  Barcelona,スペイン
- Year and Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-20590735
[Presentation] Functional analysis of the candidate genes associated with Japanese IBD2010
- Author(s)
  Yoichi Kakuta, Yoshitaka Kinouchi, Seiichi Takahashi, Tooru Shimosegawa
- Organizer
  The Kinshukai International Symposium
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21790644
[Presentation] 日本人クローン病感受性候補遺伝子TNFSF15, HLA-DQB1, IL12Bと再燃率との関連について2010
- Author(s)
  角田洋一、木内喜孝, 他10名
- Organizer
  JDDW
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21790644
[Presentation] 日本人クローン病感受性候補遺伝子TNFSF15,HLA-DQB1,IL12Bと再燃率との関連について2010
- Author(s)
  角田洋一、木内喜孝、志賀永嗣、遠藤克哉、根来健一、高橋成一、下瀬川徹
- Organizer
  第52回日本消化器病学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21790644
[Presentation] The IL12B gene is associated with the clinical course of Crohn's disease in Japanese patients.2010
- Author(s)
  Yoichi Kakuta, Yoshitaka Kinouchi, 他10名
- Organizer
  18th UEGW
- Place of Presentation
  バルセロナ(スペイン)
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-21790644
[Presentation] Functional analysis of the candidate genes associated with inflammatory bowel disease using allelic expression imbalance analysis2010
- Author(s)
  Yoichi Kakuta, Yoshitaka Kinouchi, Seiichi Takahashi, Tooru Shimosegawa
- Organizer
  US-Japan GI Executive meeting
- Place of Presentation
  東京
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21790644

1. KINOUCHI Yoshitaka (20250780)

# of Collaborated Projects: 8 results

# of Collaborated Products: 16 results
2. Shiga Hisashi (20583355)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 黒羽正剛 (70709469)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. Moroi RIntaro (90803594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 根来健一 (50375028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 兼平正史 (30177539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 八幡祥生 (30549944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 齋藤正寛 (40215562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 岩城英也 (30999644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAKUTA YOICHI 角田 洋一

KAKUTA Yoichi 角田 洋一

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Analysis of the Onset and Pathological Changes of Crohn's Disease through Somatic Mosaicism Mediated by Genomic InstabilityPrincipal Investigator

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Gene-microbiota interaction of inflammatory bowel diseasePrincipal Investigator

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Genome-wide association study of inflammatory bowel disease using population optimized array and reference panel in JapanesePrincipal Investigator

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日本人潰瘍性大腸炎感受性遺伝子SLC26A3の遺伝子多型機能解析Principal Investigator

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TNFSF15 derived from T cells may play an important role in the pathogenesis of Crohn's disease.Principal Investigator

KAKUTA YOICHI 角田洋一

KAKUTA Yoichi 角田洋一