HIRAYAMA Hiroto 平山弘人

… Alternative Names

平山弘人ヒラヤマヒロト

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Researcher Number	50525847
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 開拓研究本部, 研究員 2025: 京都大学, iPS細胞研究所, 特定研究員 2025: 岐阜大学, 糖鎖生命コア研究所, 研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人理化学研究所, 開拓研究本部, 研究員 2017: 国立研究開発法人理化学研究所, 糖鎖代謝学研究チーム, 客員研究員 2016: 国立研究開発法人理化学研究所, 糖鎖代謝学研究チーム, 協力研究員 2013: 独立行政法人理化学研究所, 糖鎖代謝学研究チーム, 協力研究員 2012: 独立行政法人理化学研究所, 糖鎖代謝学研究チーム, 特別研究員
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator 出芽酵母 / 遊離糖鎖 / 糖鎖代謝 / ER stress / secretory protein / glycoprotein / 細胞質 / 小胞体 / 糖鎖修飾 / 細胞内輸送 … More / PNGase / NGLY1 / 細胞壁 / マンノース / O-結合型糖鎖 / 酵母 / 代謝 / 糖鎖 / 新規遺伝子探索 / 遊離糖鎖解析 … More Except Principal Investigator 遊離糖鎖 / 代謝 / 糖鎖 / 糖タンパク質 / O型糖鎖 / O-マンノース / オリゴ糖転移酵素 / PNGase / N型糖鎖 / 出芽酵母 / 糖鎖代謝 Less

Analysis of the molecular mechanism of reduction of protein secretion in peptide:N-glycanase deficient cellsPrincipal Investigator
- Principal Investigator
  
  平山弘人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Institute of Physical and Chemical Research
Identification of a novel endo-O-mannosidases for developing a new tool for de-glycosylation of O-glycansPrincipal Investigator
- Principal Investigator
  
  Hirayama Hiroto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Institute of Physical and Chemical Research
Clarification of molecular mechanism for the catabolism of glycans on glycoproteins in budding yeast
- Principal Investigator
  
  Tadashi Suzuki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Institute of Physical and Chemical Research
Study of the biologogical functions of the generation of free oligosaccharidesPrincipal Investigator
- Principal Investigator
  
  HIRAYAMA Hiroto
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Institute of Physical and Chemical Research

All 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] GDP-mannose pyrophophorylase A, B (GMPPA,B) in Handbook of glycosyltransferases and related genes (N. Taniguchi, K. Honke, M. Fukuda, H. Narimatsu, Y. Yamaguchi, T. Angata eds.).2014
- Author(s)
  Hiroto Hirayama and Tadashi Suzuki
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25291030
[Book] GDP-mannose pyrophophorylase A, B (GMPPA,B) (Vol. 3, 1599-1606). In "Handbook of glycosyltransferases and related genes. 2nd Edition" (N. Taniguchi, K. Honke, M. Fukuda, H. Narimatsu, Y. Yamaguchi, T. Angata eds.)2014
- Author(s)
  Hiroto Hirayama and Tadashi Suzuki
- Total Pages
  1707
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25291030
[Book] Handbook of glycosyltransferases and related genes2013
- Author(s)
  Hirayama H., Suzuki T.
- Total Pages
  1707
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-24770136
[Book] GMPPA, B, Handbook of glycosyltransferases and related genes
- Author(s)
  Hirayama H., Suzuki T.
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-24770136
[Journal Article] Lack of the evidence for the enzymatic catabolism of Man1GlcNAc2 in Saccharomyces cerevisiae.2016
- Author(s)
  Tanim Jabid Hossain, Hiroto Hirayama, Yoichiro Harada and Tadashi Suzuki
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: 80 Issue: 1 Pages: 152-157
- DOI
  10.1080/09168451.2015.1072464
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25291030
[Journal Article] tructural analysis of free N-glycans in alpha-glucosidase mutants of Saccharomyces cerevisiae. Lack of the evidence for the occurrence of catabolic a-glucosidase acting on the N-glycans.2016
- Author(s)
  Tanim Jabid Hossain, Yoichiro Harada, Hiroto Hirayama, Haruna Tomotake, Akira Seko and Tadashi Suzuki
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 3 Pages: e0151891-e0151891
- DOI
  10.1371/journal.pone.0151891
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25291030
[Journal Article] Generation and degradation of free asparagine-linked glycans.2015
- Author(s)
  Yoichiro Harada, Hiroto Hirayama, and Tadashi Suzuki
- Journal Title
  
  Cell Mol. Life Sci.
  
  Volume: NA Issue: 13 Pages: 2509-2533
- DOI
  10.1007/s00018-015-1881-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25291030, KAKENHI-PUBLICLY-26110725, KAKENHI-PROJECT-26650040
[Journal Article] Physiological and molecular functions of the cytosolic peptide:N-glycanase.2015
- Author(s)
  Hiroto Hirayama, Akira Hosomi, and Tadashi Suzuki
- Journal Title
  
  Semin Cell Dev Biol.
  
  Volume: NA Pages: 110-120
- DOI
  10.1016/j.semcdb.2014.11.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25291030, KAKENHI-PUBLICLY-26110725
[Journal Article] ” Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation.”2013
- Author(s)
  Harada Y., Buser R., Ngwa EM., Hirayama H., Aebi M., Suzuki T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288(45) Pages: 32673-32684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770136
[Journal Article] Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation2013
- Author(s)
  Harada Y., Buser R., Ngwa EM., Hirayama H., Aebi M., Suzuki T.
- Journal Title
  
  J Biol Chem
  
  Volume: 288(45) Pages: 32673-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770136
[Journal Article] Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation2013
- Author(s)
  Harada Y, Buser R, Ngwa EM, Hirayama H, Aebi M, Suzuki T
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 45 Pages: 32673-32684
- DOI
  10.1074/jbc.m113.486985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770134, KAKENHI-PROJECT-25291030
[Presentation] Functional analysis of the generation of novel forms of free-glycans.2016
- Author(s)
  Tadashi Suzuki and Hiroto Hirayama
- Organizer
  5th RIKEN-MPG Joint Symposium on Chemical Biology at Berlin
- Place of Presentation
  Harnack-Haus, Berlin (Germany)
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] 遊離糖鎖生成に関わる新規因子の探索2014
- Author(s)
  平山　弘人、鈴木　匡
- Organizer
  第47回酵母遺伝学フォーラム
- Place of Presentation
  東京大学
- Year and Date
  2014-09-01
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] Analysis of the catabolic pathway of N-glycans in S. cerevisiae2014
- Author(s)
  Tanim Jabid Hossain, Hiroto Hirayama, Yoichiro Harada and Tadashi Suzuki
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] Analysis of the catabolic pathway of N-glycans in S. cerevisiae.2014
- Author(s)
  Tanim Jabid Hossain, Hiroto Hirayama, Yoichiro Harada and Tadashi Suzuki
- Organizer
  GlycoTOKYO2014
- Place of Presentation
  千葉大学
- Year and Date
  2014-11-04
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] 出芽酵母の生成する遊離糖鎖とその機能について2013
- Author(s)
  平山弘人、鈴木　匡
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Invited
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] 出芽酵母のO-結合型糖鎖様構造を持つ遊離糖鎖とその機能について2013
- Author(s)
  平山弘人、鈴木　匡
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪）
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] Discovery of the novel type of free glycans in Saccharomyces cerevisiae.2013
- Author(s)
  Hiroto Hirayama and Tadashi Suzuki
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology The Second Symposium
- Place of Presentation
  理化学研究所（和光）
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] Discovery of the novel type of free glycans in Saccharomyces cerevisiae.2013
- Author(s)
  Hiroto Hirayama and Tadashi Suzuki
- Organizer
  The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology
- Place of Presentation
  理化学研究所（和光）
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] 出芽酵母の生成するO-結合型糖鎖様構造を持つ遊離糖鎖とその機能について2013
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] Discovery of the novel type of free glycans in Saccharomyces cerevisiae2013
- Author(s)
  Hiroto Hirayama, Tadashi Suzuki
- Organizer
  RIKEN–Max Planck Joint Research Center for Systems Chemical Biology The 2nd Symposium
- Place of Presentation
  Wako, Japan
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] Discovery of the novel type of free glycans in Saccharomyces cerevisiae2013
- Author(s)
  Hiroto Hirayama, Tadashi Suzuki
- Organizer
  Japan-Austria joint seminar
- Place of Presentation
  Wako, Japan
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の生成するO-結合型糖鎖様構造を持つ遊離糖鎖とその機能について2013
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の遊離糖鎖生成とその調節について2013
- Author(s)
  平山　弘人、鈴木　匡
- Organizer
  第46回酵母遺伝学フォーラム
- Place of Presentation
  東北学院大学（仙台）
- Data Source
  KAKENHI-PROJECT-25291030
[Presentation] 出芽酵母の生成するO-結合型糖鎖様構造を持つ遊離糖鎖とその機能について2013
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第32回　日本糖質学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の生成する遊離糖鎖とその機能について2013
- Author(s)
  平山弘人　鈴木匡
- Organizer
  第86回　日本生化学会年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の遊離糖鎖生成とその調節について2013
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第45回酵母遺伝学フォーラム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の生成するO-結合型糖鎖様構造を持つ遊離糖鎖とその機能について2013
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第32回日本糖質学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] Discovery of the novel type of free glycans in Saccharomyces cerevisiae2013
- Author(s)
  Hirayama H., Suzuki T.
- Organizer
  Max Planck Joint Research Center for Systems Chemical Biology The 2nd Symposium
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] Discovery of the novel type of free glycans in Saccharomyces cerevisiae2013
- Author(s)
  Hirayama H., Suzuki T.
- Organizer
  Japan-Austria joint seminar
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の持つ未知のエンド型O-マンノシダーゼによる遊離糖鎖の生成2012
- Author(s)
  平山弘人
- Organizer
  第31回　日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母の持つ未知のエンド型O-マンノシダーゼによる遊離糖鎖の生成2012
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第31回日本糖質学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母における遊離O-型糖鎖の生成およびその調節機構ついて2012
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第85回日本製科学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 未知のエンド型O-マンノシダーゼによる遊離糖鎖の生成機構について2012
- Author(s)
  平山弘人、鈴木匡
- Organizer
  第44回酵母遺伝学フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 出芽酵母における遊離O-型糖鎖の生成およびその調節機構ついて2012
- Author(s)
  平山弘人
- Organizer
  第85回　日本生化学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24770136
[Presentation] 未知のエンド型O-マンノシダーゼによる遊離糖鎖の生成機構について2012
- Author(s)
  平山弘人
- Organizer
  第44回　酵母遺伝学フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24770136

1. Tadashi Suzuki (90345265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
2. HARADA Yoichiro (80464147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

HIRAYAMA Hiroto 平山 弘人

平山 弘人 ヒラヤマ ヒロト

Research Projects

Research Products

Co-Researchers

Analysis of the molecular mechanism of reduction of protein secretion in peptide:N-glycanase deficient cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of a novel endo-O-mannosidases for developing a new tool for de-glycosylation of O-glycansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of molecular mechanism for the catabolism of glycans on glycoproteins in budding yeast

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the biologogical functions of the generation of free oligosaccharidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] GDP-mannose pyrophophorylase A, B (GMPPA,B) in Handbook of glycosyltransferases and related genes (N. Taniguchi, K. Honke, M. Fukuda, H. Narimatsu, Y. Yamaguchi, T. Angata eds.).2014

Author(s)

Publisher

Data Source

[Book] GDP-mannose pyrophophorylase A, B (GMPPA,B) (Vol. 3, 1599-1606). In "Handbook of glycosyltransferases and related genes. 2nd Edition" (N. Taniguchi, K. Honke, M. Fukuda, H. Narimatsu, Y. Yamaguchi, T. Angata eds.)2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Handbook of glycosyltransferases and related genes2013

Author(s)

Total Pages

Publisher

Data Source

[Book] GMPPA, B, Handbook of glycosyltransferases and related genes

Author(s)

Publisher

Data Source

[Journal Article] Lack of the evidence for the enzymatic catabolism of Man1GlcNAc2 in Saccharomyces cerevisiae.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] tructural analysis of free N-glycans in alpha-glucosidase mutants of Saccharomyces cerevisiae. Lack of the evidence for the occurrence of catabolic a-glucosidase acting on the N-glycans.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation and degradation of free asparagine-linked glycans.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physiological and molecular functions of the cytosolic peptide:N-glycanase.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ” Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation.”2013

Author(s)

Journal Title

Data Source

[Journal Article] Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation2013

Author(s)

Journal Title

Data Source

[Journal Article] Eukaryotic oligosaccharyltransferase generates free oligosaccharides during N-glycosylation2013

Author(s)

Journal Title

DOI

Data Source

HIRAYAMA Hiroto 平山弘人

平山弘人ヒラヤマヒロト