Sakamoto Hirotsugu 坂本博次

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坂本博次サカモトヒロツグ

SAKAMOTO Hirotsugu 坂本博次

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Researcher Number	50536175
Other IDs	https://orcid.org/0000-0002-2458-1693
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 自治医科大学, 医学部, 准教授 2014 – 2016: 自治医科大学, 医学部, 講師 2011: 自治医科大学, 医学部, 助教 2009 – 2011: Jichi Medical University, 医学部, 研究員
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator トランスジェニックマウス / 腸上皮化生 / Cdx2 / Cdx1 / 十二指腸 / 胃 / 食道 Except Principal Investigator 目盛り付き先端細径透明フード / ダブルバルーン内視鏡 / 再狭窄 … More / 目盛り付き先端細径フード / ダブルバルーン小腸内視鏡 / 内視鏡的バルーン拡張術 / 小腸狭窄 / クローン病 / Lgr5 Less

Significance of endoscopic quantitative evaluation of small bowel stricture in patients with Crohn's disease and elucidation of restenosis factors after balloon dilatation
- Principal Investigator
  
  矢野智則
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jichi Medical University
Analysis of Lgr5-positive cells in the intestinal metaplasia
- Principal Investigator
  
  Hirosawa Takuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
The relationship between Cdx2 and Cdx1 in intestinal metaplastic mucosaPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Hirotsugu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University

All 2024 2015 2014 2011 2010 2009

All Journal Article

[Journal Article] Maintenance of complete mucosal healing is associated with avoiding restenosis after endoscopic balloon dilation of Crohn's disease-related small intestinal strictures2024
- Author(s)
  Dashnyam U, Nagayama M, Yano T, Sakamoto H, Mieno M, Owada J, Oguro K, Khurelbaatar T, Sunada K, Lefor AK, Yamamoto H
- Journal Title
  
  Digestive Endoscopy Open
  
  Volume: 3 Issue: 1
- DOI
  10.1002/deo2.239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07446
[Journal Article] Comparative analysis of gastrointestinal microbiota between normal and caudal-related homeobox 2 (cdx2) transgenic mice.2015
- Author(s)
  Sakamoto H, Asahara T, Chonan O, Yuki N, Mutoh H, Hayashi S, Yamamoto H, Sugano K.
- Journal Title
  
  Intest Res.
  
  Volume: 13 Issue: 1 Pages: 39-34
- DOI
  10.5217/ir.2015.13.1.39
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590926, KAKENHI-PROJECT-24590926, KAKENHI-PROJECT-26460948
[Journal Article] Cyclooxygenase 2 in gastric carcinoma is expressed in doublecortin- and CaM kinase-like-1-positive tuft cells.2014
- Author(s)
  Mutoh H, Sashikawa M, Sakamoto H, Tateno T.
- Journal Title
  
  Gut Liver
  
  Volume: 8 Issue: 5 Pages: 508-518
- DOI
  10.5009/gnl13237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590926, KAKENHI-PROJECT-24590926, KAKENHI-PROJECT-26460948
[Journal Article] Cell lineage dynamics in the process leading to intestinal metaplasia2011
- Author(s)
  Sakamoto H
- Journal Title
  
  J Gastroenterol
  
  Volume: (Epub ahead)
- NAID
  10029029095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Cell lineage dynamics in the process leading to intestinal metaplasia2011
- Author(s)
  Sakamoto H, Mutoh H, Hayakawa H, Sashikawa M, Sugano K
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Pages: 620-8
- NAID
  10029029095
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Cell lineage dynamics in the prosess leading to intestinal metaplasia2011
- Author(s)
  Sakamoto H, Mutoh H, Hayakawa H, Sashikawa M, sugano K
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Pages: 620-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Direct repression of Sonic Hedgehog expression in the stomach by Cdx2 leads to intestinal transformation2010
- Author(s)
  Mutoh H, Hayakawa H, Sashikawa M, Sakamoto H, Sugano K
- Journal Title
  
  Biochem J
  
  Volume: 427 Pages: 423-34
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach2010
- Author(s)
  Sakamoto H, Mutoh H, Sugano K
- Journal Title
  
  Scand J Gastroenterol
  
  Volume: 45 Pages: 1273-80
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Direct repression of sonic hedgehog expression in the stomach by Cdx2 leads to intestinal transformation2010
- Author(s)
  Mutoh H, Hayakawa H, Sashikawa M, Sakamoto H, Sugano K
- Journal Title
  
  Biochem J 427
  
  Pages: 423-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach2010
- Author(s)
  Sakamoto H
- Journal Title
  
  Scand J Gastroenterology
  
  Volume: 45 Pages: 1273-1280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Intestinal metaplasia in gallbladder correlates with high amylase levels in bile in patients with a morphologically normal pancreaticobiliary duct2009
- Author(s)
  Sakamoto H, Mutoh H, Ido K, Satoh S, Kumagai M, Hayakawa H, Tamada K, Sugano K
- Journal Title
  
  Hum Pathol
  
  Volume: 40 Pages: 1762-7
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach2009
- Author(s)
  Mutoh H, Hayakawa H, Sakamoto H, Sashikawa M, Sugano K
- Journal Title
  
  FEBS J
  
  Volume: 276 Pages: 5821-31
- Data Source
  KAKENHI-PROJECT-21590794
[Journal Article] Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach2009
- Author(s)
  Mutoh H, Hayakawa H, Sakamoto H, Sashikawa M, Sugano K.
- Journal Title
  
  FEBS J 276
  
  Pages: 5821-5831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590794

1. MUTOH Hiroyuki (50322392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. Hirosawa Takuya (50570660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 矢野智則 (30438634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 山本博徳 (10311937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 永山学 (80741347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Sakamoto Hirotsugu 坂本 博次

坂本 博次 サカモト ヒロツグ

SAKAMOTO Hirotsugu 坂本 博次

Research Projects

Research Products

Co-Researchers

Significance of endoscopic quantitative evaluation of small bowel stricture in patients with Crohn's disease and elucidation of restenosis factors after balloon dilatation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Lgr5-positive cells in the intestinal metaplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between Cdx2 and Cdx1 in intestinal metaplastic mucosaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Maintenance of complete mucosal healing is associated with avoiding restenosis after endoscopic balloon dilation of Crohn's disease-related small intestinal strictures2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparative analysis of gastrointestinal microbiota between normal and caudal-related homeobox 2 (cdx2) transgenic mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclooxygenase 2 in gastric carcinoma is expressed in doublecortin- and CaM kinase-like-1-positive tuft cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell lineage dynamics in the process leading to intestinal metaplasia2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cell lineage dynamics in the process leading to intestinal metaplasia2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cell lineage dynamics in the prosess leading to intestinal metaplasia2011

Author(s)

Journal Title

Data Source

[Journal Article] Direct repression of Sonic Hedgehog expression in the stomach by Cdx2 leads to intestinal transformation2010

Author(s)

Journal Title

Data Source

[Journal Article] Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach2010

Author(s)

Journal Title

Data Source

[Journal Article] Direct repression of sonic hedgehog expression in the stomach by Cdx2 leads to intestinal transformation2010

Author(s)

Journal Title

Data Source

[Journal Article] Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach2010

Author(s)

Journal Title

Data Source

[Journal Article] Intestinal metaplasia in gallbladder correlates with high amylase levels in bile in patients with a morphologically normal pancreaticobiliary duct2009

Author(s)

Journal Title

Data Source

[Journal Article] Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach2009

Author(s)

Journal Title

Data Source

[Journal Article] Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach2009

Author(s)

Journal Title

Sakamoto Hirotsugu 坂本博次

坂本博次サカモトヒロツグ

SAKAMOTO Hirotsugu 坂本博次