TAKAOKA MUNENORI 高岡宗徳

… Alternative Names

TAKAOKA Munenori 高岡宗徳

Less

Researcher Number	50548568
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 川崎医科大学, 医学部, 准教授 2012 – 2020: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Applied pharmacology / Digestive surgery Except Principal Investigator Respiratory surgery / Basic Section 50010:Tumor biology-related / Cardiovascular surgery / Applied pharmacology / Digestive surgery
Keywords	Principal Investigator 5-アミノレブリン酸 / 薬剤性消化管粘膜障害 / アミノレブリン酸 / 酸化ストレス / 腸管オルガノイド / フェロトーシス / 鉄代謝経路 / 消化管粘膜障害 / 抗がん化学療法 / 薬剤誘発性酸化ストレス … More / 医薬品副作用・薬物相互作用 / 薬剤性消化管障害 / プロバイオティクス / 5‐アミノレブリン酸 / heme oxygenase-1 / オルガノイド / 食道癌 / 食道外科学 … More Except Principal Investigator 肺扁平上皮癌 / 分子標的治療法 / 5-アミノレブリン酸（ALA） / 分子標的治療 / Midkine / 肺癌 / オルガノイド / ゲノム編集 / 扁平上皮癌 / 悪性胸膜中皮腫 / Midkaine / AKT / PIK3CA / 胸膜中皮腫 / 5-ALA / 5-アミノレブリン酸 / アミノレブリン酸 / 肺外科 / 人口転写因子 / Sox2 / Sox2遺伝子 / 食道外科学 / 11 / 食道癌 Less

鉄代謝経路に着目した抗がん剤による消化管粘膜障害の機序解明と新規支持療法の確立Principal Investigator
- Principal Investigator
  
  高岡宗徳
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kawasaki Medical School
Elucidation of mechanism of carcinogenesis and progression in lung squamous cell carcinoma with organoid technology
- Principal Investigator
  
  Fukazawa Takuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Development of strategies to treat malignant mesothelioma by novel PIK3CA inhibitors
- Principal Investigator
  
  Naomoto Yoshio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
A potential preventive effect of fecal microbiota transplantation and 5-aminolevulinic acid against anti-cancer drug-induced damage to intestinal mucosaPrincipal Investigator
- Principal Investigator
  
  Takaoka Munenori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kawasaki Medical School
Identification of novel candidate compounds for the treatment of lung squamous cell carcinoma by academic drug discovery
- Principal Investigator
  
  Fukazawa Takuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Protective efficacy of the 5-aminolevulinic acid for cisplatin nephrotoxicity
- Principal Investigator
  
  Yamatsuji Tomoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kawasaki Medical School
Development of the new therapy for the arteriosclerosis obliterans applying cellular senescence suppressive effect of 5-ALA
- Principal Investigator
  
  Hirabayashi Yoko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Kawasaki Medical School
Development of artificial transcription factors for the treatment of lung and esophageal squamous cell carcinoma
- Principal Investigator
  
  Naomoto Yoshio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Sox2 is a novel target gene for the treatment of lung squamous cell carcinoma.
- Principal Investigator
  
  Fukazawa Takuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Preclinical examination to establish a novel photodynamic therapy with 5-aminolevulinic acid for esophageal cancerPrincipal Investigator
- Principal Investigator
  
  TAKAOKA Munenori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
Development of novel therapies targeting esophageal cancer using Midkine inhibitors
- Principal Investigator
  
  NAOMOTO YOSHIO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School

All 2021 2020 2019 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] A potential protective effect of 5-aminolevulinic acid against anticancer drug-induced damage to intestinal mucosa2021
- Author(s)
  Munenori Takaoka, Naomasa Ishida, Miki Iwai, Yoshiko Tatsuta, Rie Kosaka, Etsuko Yokota, Noriko Miyake, Takuya Fukazawa, Masaki Matsubara, Tohru Tanaka, Motowo Nakajima, Naoto Ikemoto, Yoko Ochiai, and Tomoki Yamatsuji
- Journal Title
  
  Kawasaki Medical Journal
  
  Volume: 47 Pages: 47-54
- DOI
  10.11482/KMJ-E202147047
- ISSN
  0385-0234, 2434-3404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07435
[Journal Article] SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.2016
- Author(s)
  Fukazawa T, Guo M, Ishida N, Yamatsuji T, Takaoka M, Yokota E, Haisa M, Miyake N, Ikeda T, Okui T, Takigawa N, Maeda Y, Naomoto Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 20113-20113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462188
[Journal Article] SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.2016
- Author(s)
  Fukazawa T, Guo M, Ishida N, Yamatsuji T, Takaoka M, Yokota E, Haisa M, Miyake N, Ikeda T, Okui T, Takigawa N, Maeda Y, Naomoto Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 20113-20113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462141
[Journal Article] Feasibility of oral administration of S-1 as adjuvant chemotherapy in gastric cancer: 4-week S-1 administration followed by 2-week rest vs. 2-week administration followed by 1-week rest.2015
- Author(s)
  Yamatsuji T,Fujiwara Y, Matsumoto H,Hato S,Namikawa T, Hanazaki K,Takaoka M,Hayashi J,Shigemitsu K,Yoshida K,Urakami A,Uno F,Nishizaki M,Kagawa S,Ninomiya M,Fujiwara T,Hirai T,Nakamura M,Haisa M,Naomoto Y
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 3(3) Pages: 527-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08604
[Journal Article]2013
- Author(s)
  Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.
- Journal Title
  
  PLoS One
  
  Volume: 8(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591950
[Journal Article] Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.2013
- Author(s)
  Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Issue: 8 Pages: 8-8
- DOI
  10.1371/journal.pone.0071093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] 抗がん化学療法での消化管粘膜障害に対するアミノレブリン酸による保護効果の可能性2021
- Author(s)
  髙岡宗徳、石田尚正、吉田将和、渡邊達也、松原正樹、湯川拓郎、深澤拓也、羽井佐実、林次郎、吉田和弘、浦上淳、山辻知樹
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K07435
[Presentation] 抗がん化学療法での消化管粘膜障害に対するアミノレブリン酸による保護効果の可能性2020
- Author(s)
  髙岡宗徳、石田尚正、吉田将和、渡邊達也、松原正樹、湯川拓郎、深澤拓也、羽井佐実、林次郎、吉田和弘、浦上淳、山辻知樹
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K07435
[Presentation] 抗がん化学療法での消化管粘膜障害に対するアミノレブリン酸による保護効果の可能性2019
- Author(s)
  高岡宗徳
- Organizer
  川崎医科大学学術集会
- Data Source
  KAKENHI-PROJECT-16K08921
[Presentation] 5-アミノレブリン酸によるシスプラチン腎毒性抑制作用の臨床応用2017
- Author(s)
  山辻知樹，近藤健介，石田尚正，磯田竜太郎，湯川拓郎高岡宗徳，林　次郎，吉田和弘，深澤拓也，中島一毅，浦上　淳森田一郎，羽井佐　実，杭ノ瀬昌彦，猶本良夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K08604
[Presentation] Development of a novel targeted therapy for malignant mesothelioma by a midkine inhibitor.2017
- Author(s)
  Takuya Fukazawa, Yuitaka Maeda, Tomoki Yamatsuji, Munenori Takaoka, Masakazu Yoshida, Naomasa Ishida, Miki Iwai, Etsuko Yokota, Takuro Yukawa, Minoru Haisa, Noriko Miyake, Tomoko Ikeda, Nagio Takigawa, Jeffery Whitsett, Yoshio Naomoto
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  Center, Cincinnati, OH,Washington DC,USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15638
[Presentation] 食道癌術後再建胃管癌の診断および治療法の検討( Cases of Carcinoma in the Reconstructed Gastric Tube Following Esophagectomy for Esophageal Cancer).2016
- Author(s)
  山辻知樹,吉田将和,石田尚正,櫻井早也佳,湯川拓郎,平林葉子,高岡宗徳,深澤拓也,林次郎,吉田和弘,繁光薫,中島一毅,浦上淳,森田一郎,杭ノ瀬昌彦,末廣満彦,物部泰昌,春間賢,河本博文,猶本良夫
- Organizer
  第92回日本消化器内視鏡学会総会
- Place of Presentation
  神戸コンベンションセンター,神戸
- Data Source
  KAKENHI-PROJECT-15K08604
[Presentation] 人工転写因子を用いた肺扁平上皮癌に対する新規標的療法の開発2015
- Author(s)
  横田悦子、深澤拓也、山辻知樹、高岡宗徳、羽井佐実、三宅規子、池田智子、石田尚正、吉田将和、瀧川奈義夫、世良貴史、猶本良夫
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26462141
[Presentation] 人工転写因子を用いた肺扁平上皮癌に対する新規標的療法の開発2015
- Author(s)
  横田悦子1、深澤拓也1、山辻知樹1、高岡宗徳1、羽井佐実1、三宅規子2、池田智子2、石田尚正1、吉田将和1、瀧川奈義夫3、世良貴史4、猶本良夫1 (1 川崎医科大学・総合外科、2 川崎病院研究センター、3 川崎医科大学・総合内科 4、4 岡山大学・生命工学・生体機能分子設計)
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25462188
[Presentation] Midkine阻害剤を用いた非小細胞肺癌に対する新規治療法開発.2013
- Author(s)
  深澤拓也、前田豊、山辻知樹、高岡宗徳、森田一郎、瀧川奈義夫、猶本良夫
- Organizer
  第54回日本肺癌学会総会
- Place of Presentation
  東京都千代田区
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] 5-アミノレブリン酸(5-ALA)を用いた食道癌抑制の可能性2013
- Author(s)
  高岡宗徳
- Organizer
  第4回川崎医科大学　学術集会
- Place of Presentation
  川崎医科大学（岡山県倉敷市）
- Data Source
  KAKENHI-PROJECT-24591963
[Presentation] Development of novel targeted therapies for non-small cell carcinoma by novel Midkine inhibitors2013
- Author(s)
  Takuya Fukazawa, Yutaka Maeda, Huifang Hao, Tomoki Yamatsuji, Munenori Takaoka, Nagio Takigawa, and Yoshio Naomoto
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  米国ワシントンDC
- Year and Date
  2013-04-08
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] 肺腺癌に対するMidkineを標的とした新規治療法の開発2013
- Author(s)
  深澤拓也、山辻知樹、前田豊、瀧川奈義夫、高岡宗徳、森田一郎、中島元夫、ジェフリー・ウィトセット、猶本良夫
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  福岡県博多
- Year and Date
  2013-04-11
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] Inhibition of Midkine by a novel small molecule compound to treat non-small cell lung cancer2013
- Author(s)
  Takuya Fukazawa1, Huifang Hao1, Tomoki Yamatsuji1, Munenori Takaoka1, Nagio Takigawa2, Yutaka Maeda3, Junji Matsuoka4, Tatsuo Okui5, Tsuyoshi Shimo5, Yasuko Tomono6, Motowo Nakajima7, Jeffrey A. Whitsett2 and Yoshio Naomoto
- Organizer
  第72回日本癌学会　学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-23591950

1. NAOMOTO YOSHIO (00237190)

# of Collaborated Projects: 9 results

# of Collaborated Products: 14 results
2. YAMATSUJI Tomoki (40379730)

# of Collaborated Projects: 9 results

# of Collaborated Products: 16 results
3. FUKAZAWA Takuya (20379845)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
4. NAKAJIMA Motowo (90240738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. Hirabayashi Yoko (90341106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 繁光薫 (50585007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 世良貴史 (10362443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 羽井佐実 (70322229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 森田一郎 (30200413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石田尚正 (80805896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

TAKAOKA MUNENORI 高岡 宗徳

TAKAOKA Munenori 高岡 宗徳

Research Projects

Research Products

Co-Researchers

鉄代謝経路に着目した抗がん剤による消化管粘膜障害の機序解明と新規支持療法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A potential preventive effect of fecal microbiota transplantation and 5-aminolevulinic acid against anti-cancer drug-induced damage to intestinal mucosaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preclinical examination to establish a novel photodynamic therapy with 5-aminolevulinic acid for esophageal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A potential protective effect of 5-aminolevulinic acid against anticancer drug-induced damage to intestinal mucosa2021

Author(s)

Journal Title

DOI

ISSN

Data Source

[Journal Article] SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.2016

Author(s)

Journal Title

Data Source

[Journal Article] SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.2016

Author(s)

Journal Title

Data Source

[Journal Article] Feasibility of oral administration of S-1 as adjuvant chemotherapy in gastric cancer: 4-week S-1 administration followed by 2-week rest vs. 2-week administration followed by 1-week rest.2015

Author(s)

Journal Title

TAKAOKA MUNENORI 高岡宗徳

TAKAOKA Munenori 高岡宗徳