MIYAZAKI TOSHIAKI 宮崎利明

… Alternative Names

宮崎利明ミヤザキトシアキ

Miyazaki Toshiaki 宮崎利明

MIYAZAKI Toshiaki 宮崎利明

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Researcher Number	50589075
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 埼玉医科大学, 医学部, 講師 2016 – 2018: 国立研究開発法人国立がん研究センター, 研究所, 研究員 2015: 国立研究開発法人国立がん研究センター, がん分化制御解析分野, 研究員 2015: 国立研究開発法人国立がん研究センター, 研究所がん分化制御解析分野, 研究員 2014: 埼玉医科大学, 医学部, 研究員 2011 – 2012: 埼玉医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Urology / Digestive surgery Except Principal Investigator Basic Section 53040:Nephrology-related
Keywords	Principal Investigator がん微小環境 / Cancer / 腫瘍免疫 / 微小環境変化 / がん / EBAG9 / がん免疫 / 転移 / がん幹細胞 / kynurenine … More / TDO2 / Kynurenine / 肝転移 / 大腸がん / 泌尿器がん / がん腫瘍免疫 / 前立腺がん / tumor immunity / microenvironment / 腫瘍学 … More Except Principal Investigator クロト Less

The mechanisms for renal protection by klotho protein supplementation
- Principal Investigator
  
  竹中恒夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  International University of Health and Welfare
Research on renal protection by klotho protein supplementation
- Principal Investigator
  
  Takenaka Tsuneo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  International University of Health and Welfare
Elucidation of tumor microenvironmental via expression of TDO in liver metastasis of colorectal cancer and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  Miyazaki Toshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  National Cancer Center Japan
The relationship between microenvironment and tumor growth mechanism regulated by EBAG9 in urological cancer and the application to clinicalPrincipal Investigator
- Principal Investigator
  
  Miyazaki Toshiaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  National Cancer Center Japan
  Saitama Medical University
The relationship between microenvironment and growth of the cellsregulated by EBAG9 in bladder cancerPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Toshiaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Saitama Medical University

All 2023 2022 2021 2020 2018 2017 2015 2014 2013 2012 Other

All Journal Article Presentation Other

[Journal Article] Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.2023
- Author(s)
  Takenaka Tsuneo、Hasan Arif、Marumo Takeshi、Inoue Tsutomu、Miyazaki Takashi、Suzuki Hiromichi、Kurosaki Yoshifumi、Ishii Naohito、Nishiyama Akira、Hayashi Matsuhiko
- Journal Title
  
  Kidney and Blood Pressure Research
  
  Volume: 1 Issue: 1 Pages: 1-1
- DOI
  10.1159/000530469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08261, KAKENHI-PROJECT-21K07350, KAKENHI-PROJECT-23K07702, KAKENHI-PROJECT-20K08641, KAKENHI-PROJECT-22K19712, KAKENHI-PROJECT-23K24771
[Journal Article] Klotho supplementation attenuates blood pressure and albuminuria in murine model of IgA nephropathy2021
- Author(s)
  Takenaka Tsuneo、Hasan Arif、Marumo Takeshi、Kobori Hiroyuki、Inoue Tsutomu、Miyazaki Takashi、Suzuki Hiromichi、Nishiyama Akira、Ishii Naohito、Hayashi Matsuhiko
- Journal Title
  
  Journal of Hypertension
  
  Volume: Publish Ahead of Print Issue: 8 Pages: 1-10
- DOI
  10.1097/hjh.0000000000002845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08731, KAKENHI-PROJECT-20K08641, KAKENHI-PROJECT-18K07455, KAKENHI-PROJECT-21K07350
[Journal Article] Klotho supplementation ameliorates blood pressure and renal function in DBA/2-pcy mice, a model of polycystic kidney disease.2020
- Author(s)
  Takenaka T, Kobori H, Inoue T, Takashi Miyasaki T,Suzuki H, Nishiyama H, Ishii N, Hayashi M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 316 Issue: 3 Pages: F557-F564
- DOI
  10.1152/ajprenal.00299.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07455, KAKENHI-PROJECT-20K08641
[Journal Article] Extracellular vesicle-mediated EBAG9 transfer from cancer cells to tumor microenvironment promotes immune escape and tumor progression2018
- Author(s)
  Miyazaki Toshiaki、Ikeda Kazuhiro、Sato Wataru、Horie-Inoue Kuniko、Inoue Satoshi
- Journal Title
  
  Oncogenesis
  
  Volume: 7 Issue: 1 Pages: 7-7
- DOI
  10.1038/s41389-017-0022-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10560, KAKENHI-PROJECT-17H04205, KAKENHI-PROJECT-16K15496, KAKENHI-PROJECT-16K09809
[Journal Article] EBAG9 modulates host immune defense against tumor formation and metastasis by regulating cytotoxic activity of T lymphocytes.2014
- Author(s)
  Miyazaki T, Ikeda K, Horie-Inoue K, Kondo T, Takahashi S, Inoue S.
- Journal Title
  
  Oncogenesis
  
  Volume: 3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861292
[Journal Article] Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway.2014
- Author(s)
  Maruyama Y, Miyazaki T, Ikeda K, Okumura T, Sato W, Horie-Inoue K, Okamoto K, Takeda S, Inoue S.
- Journal Title
  
  PLoS One.
  
  Volume: 9(10)
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861292
[Journal Article] Amyloid precursor protein regulates migration and metalloproteinase gene expression in prostate cancer cells.2014
- Author(s)
  Miyazaki T, Ikeda K, Horie-Inoue K, Inoue S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 452(3) Pages: 828-33
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861292
[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis2023
- Author(s)
  Tsuneo Takenaka, Naohito Ishii, Yoshifumi Kurosaki, Tsutomu Inoue, Takashi Miyazaki, Akira Nishiyama, Matsuhiko Hayashi
- Organizer
  欧州腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis.2023
- Author(s)
  Tsuneo Takenaka, Naohito Ishii, Yoshifumi Kurosaki, Takashi Miyazaki, Akira Nishiyama, Matsuhiko Hayashi
- Organizer
  欧州腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07702
[Presentation] KLOTHO SUPPLEMENTATION REVERSES RENAL DYSFUNCTION AND INTERSTITIAL FIBROSIS IN REMNANT KIDNEY2022
- Author(s)
  Tsuneo Takenaka, Arif Hasan, Takeshi Marumo, Tsutomu Inoue, Takashi Miyazaki, Hiromichi Suzuki, Yoshifumi Kurosaki, Naohito Ishii, Akira Nishiyama, Matsuihiko Hayashi
- Organizer
  ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] クロト補充は多発性嚢胞腎モデルで血圧と腎機能を改善する2020
- Author(s)
  竹中恒夫, 小堀浩幸, 井上勉, 宮崎孝, 鈴木洋通, 西山成, 石井直仁, 林松彦
- Organizer
  日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] クロトが骨形成蛋白質7の発現に与える影響2020
- Author(s)
  竹中恒夫, Hasan Arif, 宮崎孝, 石井直仁, 丸茂丈史
- Organizer
  国際医療福祉大学学会
- Data Source
  KAKENHI-PROJECT-20K08641
[Presentation] 大腸がん幹細胞のメタボローム解析による肝転移メカニズムの解明2018
- Author(s)
  宮崎利明、大畑広和、曽我朋義、岡本康司
- Organizer
  第1回がんと代謝研究会・若手の会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] Elucidation of novel mechanism of liver metastasis of colon cancer through metabolome analyses of cancer stem cells2018
- Author(s)
  宮崎　利明
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] 大腸がん幹細胞のメタボローム解析による肝転移メカニズムの解明2018
- Author(s)
  宮崎　利明
- Organizer
  第1回がんと代謝研究会・若手の会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] Elucidation of novel mechanism of liver metastasis of colon cancer through metabolome analyses of cancer stem cells2018
- Author(s)
  宮崎　利明
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] 大腸がん幹細胞のメタボローム解析による新規肝転移メカニズムの解明2018
- Author(s)
  宮崎　利明
- Organizer
  第33回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] Elucidation of novel mechanism of liver metastasis of colon cancer through metabolome analyses of cancer stem cells2017
- Author(s)
  Toshiaki Miyazaki, Hirokazu Ohata, Koji Okamoto
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] 大腸がん幹細胞のメタボローム解析による肝転移メカニズムの解明2017
- Author(s)
  宮崎　利明、大畑　広和、岡本　康司
- Organizer
  第32回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] 大腸がん幹細胞のメタボローム解析による肝転移メカニズムの解明2017
- Author(s)
  宮崎　利明、大畑　広和、岡本　康司
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16K10560
[Presentation] エクソソームを介して前立腺がんのがん免疫エスケープと悪性化を引き起こすEBAG9の二つの新しい作用メカニズム2015
- Author(s)
  宮崎利明、池田和博、堀江公仁子、井上聡
- Organizer
  日本アンドロロジー学会第34回学術大会共同開催：第22回精子形成・精巣毒性研究会
- Place of Presentation
  福岡大学病院　メディカルホール（福岡県）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-26861292
[Presentation] Rhoキナーゼの抑制はALDH依存的なSOX2の誘導を介して卵巣がん幹細胞の増殖を促進する2015
- Author(s)
  宮崎利明、石黒竜也、大畑広和、吉田正行、恩田貴志、加藤友康、榎本隆之、田中憲一、中釜斉、岡本康司
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861292
[Presentation] 宿主側の EBAG9 欠損は腫瘍免疫の増強を介して in vivo での泌尿器がん腫瘍増殖を抑制する2013
- Author(s)
  宮崎利明、池田和博、堀江公仁子、井上聡
- Organizer
  第13回関東ホルモンと癌研究会
- Place of Presentation
  高崎ビューホテル(高崎市)
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-23791783
[Presentation] 前立腺がんにおいて抗アンドロゲン薬反応性に関わる新規遺伝子群の機能的スクリーニング2013
- Author(s)
  丸山洋二郎、宮崎利明、池田和博、堀江公仁子、岡本康司、竹田省、井上聡
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-23791783
[Presentation] 宿主側のEBAG9欠損は腫瘍免疫の増強を介してin vivoでの泌尿器がん腫瘍増殖を抑制する2013
- Author(s)
  宮崎　利明
- Organizer
  第13回　関東ホルモンと癌研究会
- Place of Presentation
  高崎ビューホテル　(高崎市）
- Data Source
  KAKENHI-PROJECT-23791783
[Presentation] 膀胱がん増殖制御におけるEBAG9の役割2012
- Author(s)
  宮崎　利明
- Organizer
  第10回　RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学日高キャンパス　創立30周年記念講堂　（日高市）
- Data Source
  KAKENHI-PROJECT-23791783
[Presentation] 膀胱がん増殖制御における EBAG9の役割2012
- Author(s)
  宮崎利明、池田和博、堀江公仁子、井上聡
- Organizer
  第10回 RCGM フロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学日高キャンパス創立 30 周年記念講堂(日高市)
- Data Source
  KAKENHI-PROJECT-23791783
[Presentation] 前立腺がん増殖制御におけるAPPとEBAG9の役割
- Author(s)
  宮崎　利明
- Organizer
  第34回　日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Data Source
  KAKENHI-PROJECT-23791783
[Presentation] EBAG9 in hosts as a modulator for tumor growth and metastasis
- Author(s)
  Toshiaki Miyazaki, Kazuhiro Ikeda, Kuniko Horie-Inoue, Satoshi Inoue
- Organizer
  第23回　日本がん転移学会
- Place of Presentation
  金沢文化ホール、金沢ニューグランドホテル（石川県金沢市）
- Year and Date
  2014-07-09 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26861292
[]

1. Takenaka Tsuneo (90179656)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. アリフ・ウルハサン (00570368)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 西山成 (10325334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 丸茂丈史 (70265817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 石井直仁 (80212819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 宮崎孝 (30265417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 黒崎祥史 (20602030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. INOUE Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. HASAN Ul arif

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

MIYAZAKI TOSHIAKI 宮崎 利明

宮崎 利明 ミヤザキ トシアキ

Miyazaki Toshiaki 宮崎 利明

MIYAZAKI Toshiaki 宮崎 利明

Research Projects

Research Products

Co-Researchers

The mechanisms for renal protection by klotho protein supplementation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on renal protection by klotho protein supplementation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of tumor microenvironmental via expression of TDO in liver metastasis of colorectal cancer and its clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between microenvironment and tumor growth mechanism regulated by EBAG9 in urological cancer and the application to clinicalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between microenvironment and growth of the cellsregulated by EBAG9 in bladder cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Klotho supplementation attenuates blood pressure and albuminuria in murine model of IgA nephropathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Klotho supplementation ameliorates blood pressure and renal function in DBA/2-pcy mice, a model of polycystic kidney disease.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular vesicle-mediated EBAG9 transfer from cancer cells to tumor microenvironment promotes immune escape and tumor progression2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EBAG9 modulates host immune defense against tumor formation and metastasis by regulating cytotoxic activity of T lymphocytes.2014

Author(s)

Journal Title

Data Source

[Journal Article] Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway.2014

Author(s)

Journal Title

Data Source

[Journal Article] Amyloid precursor protein regulates migration and metalloproteinase gene expression in prostate cancer cells.2014

Author(s)

Journal Title

Data Source

[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis2023

Author(s)

Organizer

Data Source

[Presentation] Klotho deficiency induces regulatory T cells in murine lupus nephritis.2023

Author(s)

Organizer

Data Source

[Presentation] KLOTHO SUPPLEMENTATION REVERSES RENAL DYSFUNCTION AND INTERSTITIAL FIBROSIS IN REMNANT KIDNEY2022

Author(s)

Organizer

MIYAZAKI TOSHIAKI 宮崎利明

宮崎利明ミヤザキトシアキ

Miyazaki Toshiaki 宮崎利明

MIYAZAKI Toshiaki 宮崎利明

[Presentation] エクソソームを介して前立腺がんのがん免疫エスケープと悪性化を引き起こすEBAG9の二つの新しい作用メカニズム2015

[Presentation] 宿主側のEBAG9欠損は腫瘍免疫の増強を介してin vivoでの泌尿器がん腫瘍増殖を抑制する2013