Marumo Takeshi 丸茂丈史

… Alternative Names

Researcher Number	70265817
Other IDs
External Links
Affiliation (Current)	2018 : 東京大学, 先端科学技術研究センター, 特任准教授
Affiliation (based on the past Project Information) *help	2015 – 2018 : 東京大学, 先端科学技術研究センター, 特任准教授 2016 – 2017 : 東京大学, 医学部附属病院, その他 2015 : 東京大学, 先端科学技術研究センター, 准教授 2015 : 東京大学, 先端科学技術研究センター臨床エピジェネティクス講座, 特任准教授 2012 – 2014 : 東京大学, 先端科学技術研究センター, 特任講師 … More
Review Section/Research Field	Principal Investigator Kidney internal medicine Except Principal Investigator Kidney internal medicine / Endocrinology / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator エピジェネティクス / 糖尿病性腎症 / アルドステロン / ヒストン脱アセチル化酵素 / DNAメチル化 / histone deacetylase / 内皮障害 / 抗酸化薬 / DNA メチル化 / renal regeneration … More Except Principal Investigator ミネラルコルチコイド / 食塩感受性高血圧 / 高血圧 / 内科 / エピゲノム / アルドステロン / DNAメチル化 / ペンドリン / コルチゾール / 糖質コルチコイド / 遠位尿細管 / 鉱質コルチコイド / エピジェネティクス / 腎障害 / 糖尿病性腎症 / 酸塩基異常 / 鉱質コルチコイド受容体 / 腎臓 / ナノキャリア / ミネラルコルチコイド受容体 Less

ナノキャリアを用いたsiRNAデリバリーによる糖尿病性腎症治療法の開発Ongoing
- Principal Investigator
  
  藤田敏郎
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
１細胞解析法を用いた糖尿病性腎症でのエピゲノム異常成立機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  丸茂丈史
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Exploration of gluco- and mineralocorticoid-dependent sodium transporter system involved in salt sensitive hypertension
- Principal Investigator
  
  Fujita Toshiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  The University of Tokyo
Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunctionOngoing
- Principal Investigator
  
  藤田敏郎
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
生活習慣病の高血圧／臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索
- Principal Investigator
  
  藤田敏郎
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Exploration of epigenome abnormalities involved in salt sensitive hypertension
- Principal Investigator
  
  Fujita Toshiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Exploration of epigenetic abnormality of diabetic kidney disease for novel therapyPrincipal Investigator
- Principal Investigator
  
  Marumo Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Studies of epigenetic abnormalities in chronic kidney disease as a novel therapeutic targetPrincipal Investigator
- Principal Investigator
  
  MARUMO Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
  Kyorin University
Development of new measure for chronic kidney disease treatment using endothelial progenitor cellsPrincipal Investigator
- Principal Investigator
  
  TAKESHI Marumo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
腎臓前駆細胞を用いた腎炎の細胞治療Principal Investigator
- Principal Investigator
  
  丸茂丈史
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

[Book] 別冊医学のあゆみ　【クリニカルエピゲノミクス】各種疾患　腎臓病にかかわるエピゲノム異常　糖尿病性腎症を中心に2016
- Author(s)
  丸茂丈史, 下澤達雄
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-16K15466
[Book] 遺伝子医学MOOK25号エピジェネティクスと病気、「高血圧、腎臓病でのエピジェネティクスの役割」の項を執筆2013
- Author(s)
  丸茂丈史、藤田敏郎
- Total Pages
  6
- Publisher
  メディカルドゥ社
- Data Source
  KAKENHI-PROJECT-25461230
[Book] エピジェネティクスキーワード事典、「腎疾患」の項を執筆2013
- Author(s)
  丸茂丈史、藤田敏郎
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25461230
[Journal Article] Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin2018
- Author(s)
  Hirohama D, Ayuzawa N, Ueda K, Nishimoto M, Kawarazaki W, Watanabe A, Shimosawa T, Marumo T, Shibata S, Fujita T
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume : 29 Pages : 57-68
- DOI
  10.1681/asn.2017030243
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15466, KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-26860546, KAKENHI-PROJECT-15K19443
[Journal Article] DKDの基礎、エピジェネティック異常2018
- Author(s)
  丸茂丈史
- Journal Title
  
  腎と透析
  
  Volume : 84 Pages : 185-189
- Data Source
  KAKENHI-PROJECT-15H05788
[Journal Article] DKDの基礎、エピジェネティック異常2018
- Author(s)
  丸茂丈史
- Journal Title
  
  腎と透析
  
  Volume : 84 Pages : 185-189
- Data Source
  KAKENHI-PROJECT-16K15466
[Journal Article] Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney.2018
- Author(s)
  Uchida K, Tanaka Y, Ichikawa H, Watanabe M, Mitani S, Morita K, Fujii H, Ishikawa M, Yoshino G, Okinaga H, Nagae G, Aburatani H, Ikeda Y, Susa T, Tamamori-Adachi M, Fukusato T, Uozaki H, Okazaki T, Iizuka M
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume : 314
- DOI
  10.1152/ajprenal.00390.2017
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08987, KAKENHI-PROJECT-16K15466, KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-15K19443
[Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, and Toshiro Fujita
- Journal Title
  
  Hypertension
  
  Volume : ―
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15466
[Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017
- Author(s)
  Ueda K, Nishimoto M, Hirohama D, Ayuzawa N, Kawarazaki W, Watanabe A, Shimosawa T, Loffing J, Zhang MZ, Marumo T, Fujita T
- Journal Title
  
  Hypertension
  
  Volume : 70 Pages : 111-118
- DOI
  10.1161/hypertensionaha.116.08966
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15K19443
[Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, and Toshiro Fujita
- Journal Title
  
  Hypertension
  
  Volume : -
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15494
[Journal Article] 糖尿病性腎症におけるエピジェネティック異常2017
- Author(s)
  丸茂丈史
- Journal Title
  
  医学のあゆみ
  
  Volume : 260 Pages : 674-675
- Data Source
  KAKENHI-PROJECT-16K15466
[Journal Article] Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury.2016
- Author(s)
  Nobuhiro Ayuzawa, Miki Nagase, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Takeshi Marumo, Atsu Aiba, Takayuki Sakurai, Takayuki Shindo, Toshiro Fujita
- Journal Title
  
  Hypertension.
  
  Volume : 67 Pages : 99-106
- DOI
  10.1161/hypertensionaha.115.06054
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860546, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-25461230, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-26670426, KAKENHI-PROJECT-26670427, KAKENHI-PROJECT-26293085
[Journal Article] 【エピゲノム研究】第３章　疾患エピゲノム研究　高血圧・腎疾患のエピゲノム異常　環境因子とメタボリックメモリー2016
- Author(s)
  丸茂丈史, 藤田敏郎
- Journal Title
  
  実験医学増刊
  
  Volume : 34 Pages : 128-33
- Data Source
  KAKENHI-PROJECT-16K15466
[Journal Article] Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney2015
- Author(s)
  Marumo T, Yagi S, Kawarazaki W, Nishimoto M, Ayuzawa N, Watanabe A, Ueda K, Hirahashi J, Hishikawa K, Sakurai H, Shiota K, Fujita T.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume : 印刷中 Pages : 2333-2397
- DOI
  10.1681/asn.2014070665
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860669, KAKENHI-PROJECT-15H03001, KAKENHI-PROJECT-25461230, KAKENHI-PROJECT-26670426
[Journal Article] Rac1-mediated activation of mineralocorticoid receptor in pressure overload-induced cardiac injury2015
- Author(s)
  Ayuzawa N, Nagase M, Ueda K, Nishimoto M, Kawarazaki W, Marumo T, Sakurai T, Shindo T, Fujita T
- Journal Title
  
  Hypertension
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02538
[Journal Article] Geller DS, Tanaka H, Fujita T Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension.2011
- Author(s)
  Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T.
- Journal Title
  
  Nat Med.2011
  
  Volume : 17 Pages : 573-580
- DOI
  10.1038/nm.2337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591213, KAKENHI-PROJECT-22590879
[Journal Article] 腎臓疾患におけるエピジェネティックスの意義2010
- Author(s)
  丸茂丈史
- Journal Title
  
  腎と透析
  
  Volume : Vol 69,No3 Pages : 363-367
- Data Source
  KAKENHI-PROJECT-22590879
[Journal Article] Epigenetic Regulation of BMP7 in the Regenerative Response to Ischemia2008
- Author(s)
  Marumo T, et. al.
- Journal Title
  
  J Am Soc Nephrol 掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] NF-kappaB-dependent genes induced by proteinuria and identified using DNA microarrays2008
- Author(s)
  Takase O, Marumo T, Hishikawa K, Fujita T, Quigg RJ, Hayashi M
- Journal Title
  
  Clin Exp Nephrol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Epigenetic Regulation of BMP7 in the Regenerative Response to Ischemia2008
- Author(s)
  Marumo T, et. al.
- Journal Title
  
  J Am Soc Nephrol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Epigenetic Regulation of BMP7 in the Regenerative Response to Ischemia2008
- Author(s)
  Marumo T, Hishikawa K, Yoshikawa M, Fujita T
- Journal Title
  
  J Am Soc Nephrol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] NF-kappaB-dependent genes induced by proteinuria and identified using DNA microarrays2008
- Author(s)
  Takase O, Marumo T, et. al.
- Journal Title
  
  Clin Exp Nephrol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury2007
- Author(s)
  Imai N, Hishikawa K, Marumo T, et. al.
- Journal Title
  
  Stem Cells 25
  
  Pages : 2469-2475
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Angiotensin II type 1 receptor blockade prevents decrease in adult stem-like cells in kidney after ureteral obstruction2007
- Author(s)
  Marumo T, Hishikawa K, Matsuzaki Y, Imai N, Takase O, Shimosawa T, Okano H, Fujita T
- Journal Title
  
  Eur J Pharmacol 573
  
  Pages : 216-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal tran sition induced by TGF-betal in human renal epithelial cells2007
- Author(s)
  Yoshikawa M, Hishikawa K, Marumo T, et. al.
- Journal Title
  
  J Am Soc Nephrol 18
  
  Pages : 58-65
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Angiotensin II type 1 receptor blockade prevents decrease in adult stem-like cells in kidney after ureteral obstruction2007
- Author(s)
  Marumo T, et. al.
- Journal Title
  
  Eur J Pharmacol 573
  
  Pages : 216-220
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-betal in human renal epithelial cells2007
- Author(s)
  Yoshikawa, M., Hishikawa, K., Marumo, T., Fujita, T.
- Journal Title
  
  J Am Soc Nephrol 18
  
  Pages : 58-65
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-betal in human renal epithelial cells2007
- Author(s)
  Yoshikawa M, Hishikawa K, Marumo T, Fujita T
- Journal Title
  
  J Am Soc Nephrol 18
  
  Pages : 58-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury2007
- Author(s)
  Imai N, Hishikawa K, Marumo T, Hirahashi J, Inowa T, Matsuzaki Y, Okano H, Kitamura T, Salant D, Fujita T
- Journal Title
  
  Stem Cells 25
  
  Pages : 2469-2475
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Adosterone impairs bone marrow-derived progenitor cell formation2006
- Author(s)
  Marumo, T., Uchimura, H., Hayashi, M., Hishikawa, K., Fujita, T.
- Journal Title
  
  Hypertension 48
  
  Pages : 490-496
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Aldosterone impairs bone marrow-derived progenitor cell formation2006
- Author(s)
  Marumo T, et. al.
- Journal Title
  
  Hypertension 48
  
  Pages : 490-496
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Aldosterone impairs bone marrow-derived progenitor cell formation2006
- Author(s)
  Marumo T, Uchimura H, Hayashi M, Hishikawa K, Fujita T
- Journal Title
  
  Hypertension 48
  
  Pages : 490-496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Journal Article] Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis2005
- Author(s)
  Hideki Uchimura, Takeshi Marumo et al.
- Journal Title
  
  Journal of the American Society of Nephrology (印刷中)
- Data Source
  KAKENHI-PROJECT-15790429
[Journal Article] NF-kappaB dependent increase in intrarenal angiotensin II induced by proteinuria2005
- Author(s)
  Osamu Takase, Takeshi Marumo et al.
- Journal Title
  
  Kidney International 68
  
  Pages : 464-473
- Data Source
  KAKENHI-PROJECT-15790429
[Journal Article] Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis2005
- Author(s)
  Hideki Uchimura, Takeshi Marumo et al.
- Journal Title
  
  Journal of the American Society of Nephrology 16
  
  Pages : 997-1004
- Data Source
  KAKENHI-PROJECT-15790429
[Journal Article] 血管新生細胞療法の糸球体腎炎への応用2004
- Author(s)
  丸茂丈史, 内村英輝, 他
- Journal Title
  
  血管 Vol.27,No.3
  
  Pages : 83-88
- Data Source
  KAKENHI-PROJECT-15790429
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017
- Author(s)
  西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
- Organizer
  第90回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017
- Author(s)
  河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017
- Author(s)
  渡邉篤史丸茂丈史河原崎和歌子西本光宏鮎澤信宏広浜大五郎上田浩平熊谷裕生藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 加齢と食塩感受性高血圧～抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する～2017
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017
- Author(s)
  河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Organizer
  AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017
- Author(s)
  河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Organizer
  AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017
- Author(s)
  西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
- Organizer
  第90回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Therapeutic strategy against diabetic kidney disease based on the epigenetic information of the kidney2017
- Author(s)
  丸茂丈史
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017
- Author(s)
  上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Organizer
  AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 加齢と食塩感受性高血圧～抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する～2017
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017
- Author(s)
  上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病腎メサンギウム細胞のDNAメチル化異常によるTGFｂ発現増加をRA系阻害薬は抑制する2017
- Author(s)
  大庭成喜、広浜大五郎、鮎澤信宏、西本光宏、河原崎和歌子、上田浩平、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病腎メサンギウム細胞のDNAメチル化異常によるTGFｂ発現増加をRA系阻害薬は抑制する2017
- Author(s)
  大庭成喜、広浜大五郎、鮎澤信宏、西本光宏、河原崎和歌子、上田浩平、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017
- Author(s)
  渡邉篤史丸茂丈史河原崎和歌子西本光宏鮎澤信宏広浜大五郎上田浩平熊谷裕生藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017
- Author(s)
  渡邉篤史丸茂丈史河原崎和歌子西本光宏鮎澤信宏広浜大五郎上田浩平熊谷裕生藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 加齢と食塩感受性高血圧～抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する～2017
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016
- Author(s)
  河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016
- Author(s)
  鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016
- Author(s)
  鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016
- Author(s)
  鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎臓エピゲノム情能に基づく生活習慣病に対する治療戦略2016
- Author(s)
  丸茂丈史, 藤田敏郎
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] The mechanism of blood pressure elevation in distal nephron-specific Hsd11b2 knockout mice2016
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Nobuhiro Ayuzawa, Daigoro Hirohama, Atsushi Watanabe, Takeshi Marumo, Toshiro Fujita
- Organizer
  The 41st International Aldosterone Conference Aldosterone and Mineralocorticoids
- Place of Presentation
  Boston, USA
- Year and Date
  2016-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 高血圧の個別化医療食塩感受性と個別医療2016
- Author(s)
  下澤達雄, 丸茂丈史, 宿谷賢一, 小倉彩世子
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 糖尿病性腎症で核内受容体PXRはエピジェネティクス異常をきたし線維化因子RGC32を増加させる2016
- Author(s)
  渡邉篤史, 丸茂丈史, 河原崎和歌子, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 熊谷裕生, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016
- Author(s)
  河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016
- Author(s)
  河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎臓エピゲノム情能に基づく生活習慣病に対する治療戦略2016
- Author(s)
  丸茂丈史, 藤田敏郎
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] 腎臓エピゲノム情能に基づく生活習慣病に対する治療戦略2016
- Author(s)
  丸茂丈史, 藤田敏郎
- Organizer
  第39回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病性腎症で核内受容体PXRはエピジェネティクス異常をきたし線維化因子RGC32を増加させる2016
- Author(s)
  渡邉篤史, 丸茂丈史, 河原崎和歌子, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 熊谷裕生, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] エピジェネティクス情報に基づく腎臓病へのアプローチ2016
- Author(s)
  丸茂丈史
- Organizer
  第46回日本腎臓学会東部学術大会
- Place of Presentation
  東京
- Year and Date
  2016-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K15466
[Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease2015
- Author(s)
  Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
- Organizer
  Kidney Week 2015 ASN Annual Meeting
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられるエピジェネティック異常は血糖治療に抵抗性を示す2015
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、上田浩平、菱川慶一、櫻井裕之、藤田敏郎
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26670426
[Presentation] 遠位ネフロン特異的Rac1欠損マウスを用いたRac1-ミネラロコルチコイド受容体（MR）経路の解析2015
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Eplerenoneは塩分過剰摂取によるRA系阻害抵抗性腎障害を抑制する−EVALUATE試験サブ解析−2015
- Author(s)
  西本光宏、大津洋、丸茂丈史、河原崎和歌子、鮎澤信宏、上田浩平、広浜大五郎、渡邉篤史、藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease2015
- Author(s)
  Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
- Organizer
  Kidney Week 2015 ASN Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease.2015
- Author(s)
  Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
- Organizer
  Kidney Week 2015 ASN Annual Meeting
- Place of Presentation
  San Diego Convention Center, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670426
[Presentation] 会長特別企画「エピゲノムと循環器疾患」招待講演 Dysregulation of the epigenome in diabetic nephropathy2015
- Author(s)
  丸茂丈史
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられるエピジェネティック異常は血糖治療に抵抗性を示す2015
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、上田浩平、菱川慶一、櫻井裕之、藤田敏郎
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ　東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 近位尿細管の核内受容体Pxrは糖尿病腎症でエピゲノム変化を介して発現が更新する2015
- Author(s)
  渡邉篤史　丸茂丈史　河原崎和歌子　西本光宏　鮎澤信宏　広浜大五郎　上田浩平　熊谷裕生　藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 腎臓エピジェネティクス異常の診断・治療への応用の可能性2014
- Author(s)
  丸茂丈史
- Organizer
  第37回日本高血圧学会総会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられる治療抵抗性DNAメチル化異常2014
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、上田浩平、渡邉篤史、藤田敏郎
- Organizer
  第6回腎疾患と高血圧研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-12
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病による腎臓近位尿細管DNAメチル化異常2014
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、早川晃司、廣澤瑞子、塩田邦郎、藤田敏郎
- Organizer
  第8回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2014-05-26
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられる治療抵抗性エピジェネティック異常2014
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、菱川慶一、櫻井裕之、藤田敏郎
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられる治療抵抗性DNAメチル化異常2014
- Author(s)
  丸茂丈史
- Organizer
  第18回日本心血管内分泌代謝学会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられる治療抵抗性DNAメチル化異常2014
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、上田浩平、渡邉篤史、藤田敏郎
- Organizer
  第6回腎疾患と高血圧研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-12
- Data Source
  KAKENHI-PROJECT-26670426
[Presentation] 糖尿病性腎症にみられる治療抵抗性エピジェネティック異常2014
- Author(s)
  丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、菱川慶一、櫻井裕之、藤田敏郎
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-26670426
[Presentation] Epigenetic modulation of diabetic nephropathy2014
- Author(s)
  丸茂丈史
- Organizer
  International Society of Nephrology, Nexus Symposium ‘Hypertension and the Kidney’
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 腎障害にかかわる細胞特異的なエピジェネティック異常2013
- Author(s)
  丸茂丈史
- Organizer
  第56回日本腎臓学会学術総会(招待講演)
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2013-05-12
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 糖尿病性腎症にみられるnox4DNA脱メチル化2012
- Author(s)
  丸茂丈史
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  北里大学薬学部 (東京都)
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] gadd45beta は TGF-beta で誘導され抗線維化作用をもつ2012
- Author(s)
  丸茂丈史
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 糖尿病性腎症にみられるnox4DNAメチル化異常2011
- Author(s)
  丸茂丈史
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  栃木総合文化センター(栃木県)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 糖尿病性腎症にみられるDNAメチル化異常2011
- Author(s)
  丸茂丈史
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] TGF-betaで誘導される gadd45betaのもつ腎臓抗線維化作用2011
- Author(s)
  丸茂丈史
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] TGF-betaで誘導されるgadd45betaのもつ腎臓抗線維化作用2011
- Author(s)
  丸茂丈史
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] バルプロ酸はHDAC阻害作用を介して尿細管間質障害を改善する2010
- Author(s)
  丸茂丈史
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] バルプロ酸はHDAC阻害作用を介して尿細管間質障害を改善する2010
- Author(s)
  丸茂丈史
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] HDAC5はエネルギーセンサーとして働きBMP7誘導を介して腎臓尿細管再生に関与する2008
- Author(s)
  丸茂丈史, 他3名
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] 演題名:HDAC5はエネルギーセンサーとして働きBMP7誘導を介して腎臓尿細管再生に関与する2007
- Author(s)
  丸茂丈史, 他3名
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-13
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] HDAC5はエネルギーセンサーとして働き、虚血後の腎臓でのヒストン再アセチル化とBMP7誘導に関与する2007
- Author(s)
  丸茂丈史, 他3名
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] アルドステロンは酸化的ストレスを介して骨髄由来血管新生細胞の生成を抑制する2007
- Author(s)
  丸茂丈史, 他4名
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-03-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] HDAC5はエネルギー枯渇後に減少し、尿細管再生におけるエピジェネティック制御に関与する2007
- Author(s)
  丸茂丈史, 他3名
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Year and Date
  2007-05-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] Epigenetic mechanisms involved in regeneration of renal epithelial cells after ischemia2007
- Author(s)
  丸茂丈史, 他3名
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  東京
- Year and Date
  2007-12-03
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] Epigenetic mechanisms involved in regeneration of renal epithelial cells after ischemia2007
- Author(s)
  Takeshi Marumo, Keiichi Hishikawa, Masahiro Yoshikawa, and Toshiro Fujita
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] 自己再生能を用いた腎疾患治療法の開発-血管新生細胞療法の腎疾患への有効性-2006
- Author(s)
  丸茂丈史, 他2名
- Organizer
  第1回Vascular Biology Innovation Conference
- Place of Presentation
  東京
- Year and Date
  2006-08-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] 腎虚血後の尿細管再生にヒストンリモデリングが関与する2006
- Author(s)
  丸茂丈史, 他4名
- Organizer
  第49回日本腎臓学会学術総会
- Place of Presentation
  東京
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] Aldosterone reduces vascular endothelial growth factor receptor-2 expression and impairs bone marrow-derived progenitor cell formation2006
- Author(s)
  Marumo T, et. al.
- Organizer
  21st Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Fukuoka
- Year and Date
  2006-10-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] 虚血性腎不全後の尿細管再生におけるエピジェネティック制御2006
- Author(s)
  丸茂丈史, 他4名
- Organizer
  第7回腎不全病態治療研究会
- Place of Presentation
  東京
- Year and Date
  2006-12-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] Epigenetic mechanisms involved in regeneration of renal epithelial cells after ischemia2006
- Author(s)
  Marumo T, et. al.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] Aldosterone inhibits bone marrow-derived progenitor cell formation by reducing vascular endothelial growth factor receptor-2 expression2006
- Author(s)
  Marumo T, et. al.
- Organizer
  ISH Symposium for Aldosterone and Hypertension
- Place of Presentation
  Tokyo
- Year and Date
  2006-10-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] Aldosterone reduces vascular endothelial growth factor receptor-2 expression via increased reactive oxygen species formation in bone marrow-derived progenitor cells2006
- Author(s)
  Marumo T., et. al.
- Organizer
  American Society of Nephrology Renal Week 2006
- Place of Presentation
  San Diego, USA
- Year and Date
  2006-11-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590882
[Presentation] gadd45beta はTGF-betaで誘導され抗線維化作用をもつ
- Author(s)
  丸茂丈史
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 腎疾患にみられるエピジェネティック異常の意義
- Author(s)
  丸茂丈史
- Organizer
  第80回関東小児腎臓研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられるnox4 DNA脱メチル化
- Author(s)
  丸茂丈史
- Organizer
  第 126 回　日本薬理学会関東部会
- Place of Presentation
  北里大学薬学部(東京都)
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 腎障害にかかわる細胞特異的なエピジェネティック異常
- Author(s)
  丸茂丈史
- Organizer
  第56回日本腎臓学会学術総会　ワークショップ
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25461230
[Presentation] 糖尿病性腎症にみられるDNAメチル化異常
- Author(s)
  丸茂丈史
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 腎障害にかかわる細胞特異的なエピジェネティック異常
- Author(s)
  丸茂丈史
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム(東京都)
- Invited
- Data Source
  KAKENHI-PROJECT-22590879
[Presentation] 糖尿病性腎症にみられるnox4 DNAメチル化異常
- Author(s)
  丸茂丈史
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮、栃木総合文化センター
- Data Source
  KAKENHI-PROJECT-22590879

1. Fujita Toshiro (10114125)

# of Collaborated Projects : 5results

# of Collaborated Products : 51results
2. KAWARAZAKI Wakako (50424594)

# of Collaborated Projects : 3results

# of Collaborated Products : 33results
3. 鮎澤信宏 (50459517)

# of Collaborated Projects : 3results

# of Collaborated Products : 44results
4. 西本光宏 (90646572)

# of Collaborated Projects : 2results

# of Collaborated Products : 26results
5. 広浜大五郎 (20749353)

# of Collaborated Projects : 2results

# of Collaborated Products : 15results
6. 柴田茂 (60508068)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
7. 下澤達雄 (90231365)

# of Collaborated Projects : 2results

# of Collaborated Products : 12results
8. 大庭成喜 (80361492)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
9. HIRAHASHI Junichi (70296573)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 上田浩平 (80735697)

# of Collaborated Projects : 1results

# of Collaborated Products : 25results
11. 森典子 (80431857)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
12. 桜井敬之

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 新藤隆行

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 長瀬美樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
15. 菱川慶一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
16. 永江玄太

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

Marumo Takeshi 丸茂 丈史

MARUMO Takeshi 丸茂 丈史

TAKESHI Marumo 丸茂 丈史

Research Projects

Research Products

Co-Researchers

ナノキャリアを用いたsiRNAデリバリーによる糖尿病性腎症治療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

１細胞解析法を用いた糖尿病性腎症でのエピゲノム異常成立機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of gluco- and mineralocorticoid-dependent sodium transporter system involved in salt sensitive hypertension

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunctionOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生活習慣病の高血圧／臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of epigenome abnormalities involved in salt sensitive hypertension

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of epigenetic abnormality of diabetic kidney disease for novel therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of epigenetic abnormalities in chronic kidney disease as a novel therapeutic targetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new measure for chronic kidney disease treatment using endothelial progenitor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎臓前駆細胞を用いた腎炎の細胞治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 別冊医学のあゆみ 【クリニカルエピゲノミクス】 各種疾患 腎臓病にかかわるエピゲノム異常 糖尿病性腎症を中心に2016

Author(s)

Publisher

Data Source

[Book] 遺伝子医学MOOK25号 エピジェネティクスと病気、「高血圧、腎臓病でのエピジェネティクスの役割」の項を執筆2013

Author(s)

Total Pages

Publisher

Data Source

[Book] エピジェネティクスキーワード事典、「腎疾患」の項を執筆2013

Author(s)

Total Pages

Publisher

Data Source

Marumo Takeshi 丸茂丈史

MARUMO Takeshi 丸茂丈史

TAKESHI Marumo 丸茂丈史

[Book] 別冊医学のあゆみ　【クリニカルエピゲノミクス】各種疾患　腎臓病にかかわるエピゲノム異常　糖尿病性腎症を中心に2016

[Book] 遺伝子医学MOOK25号エピジェネティクスと病気、「高血圧、腎臓病でのエピジェネティクスの役割」の項を執筆2013

[Journal Article] 【エピゲノム研究】第３章　疾患エピゲノム研究　高血圧・腎疾患のエピゲノム異常　環境因子とメタボリックメモリー2016