UMEMOTO TERUMASA 梅本晃正

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Umemoto Terumasa 梅本晃正

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Researcher Number	50620225
Other IDs	https://orcid.org/0000-0003-0423-9003
Affiliation (Current)	2024: 熊本大学, 国際先端医学研究機構, 特定事業教員
Affiliation (based on the past Project Information) *help	2024: 熊本大学, 国際先端医学研究機構, 特定事業教員 2019 – 2023: 熊本大学, 国際先端医学研究機構, 特任准教授 2015 – 2018: 熊本大学, 国際先端医学研究機構, 特任助教 2015: 熊本大学, 国際先端医学研究機構, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Medium-sized Section 27:Chemical engineering and related fields / Basic Section 56060:Ophthalmology-related / Basic Section 90110:Biomedical engineering-related / Broad Section I / Hematology
Keywords	Principal Investigator 造血幹細胞 / グルタミン代謝 / クロマチン状態 / エネルギー代謝 / インテグリン / サイトカインシグナル Except Principal Investigator 造血幹細胞 / ミトコンドリア / セルソーティング / 生物化学工学 … More / マイクロ流体デバイス / 循環障害 / 炎症 / 生体イメージング / 網羅的解析 / 力学刺激 / メカニカルストレス / オンチップ / 伸展刺激 / メカノバイオロジー / 方向性運動 / 微小流体デバイス / 血管壁伸展 / 血管内腔圧 / 血流 / ペリサイト / 血管内皮細胞 / 血管新生 / 造血微小環境(ニッチ) / 造血微小環境（ニッチ） / 造血微小循環（ニッチ) / 自己複製 / 不均等分裂 / 造血微小環境（ニッチ) / 白血病幹細胞 / 炎症性サイトカイン / 細胞周期 / 巨核球 / 幹細胞制御 / 人工ニッチ / 幹細胞老化 / 幹細胞ニッチ / 細胞回転 / 細胞代謝 / ニッチ Less

グルタミノリシスに依存しない造血幹細胞の自己複製分裂誘導機構Principal Investigator
- Principal Investigator
  
  梅本晃正
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kumamoto University
生体イメージングと網羅的解析によるミトコンドリア面からみた緑内障とその治療法探索
- Principal Investigator
  
  瀧原祐史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kumamoto University
「硬さ」を計測し操作する造血幹細胞の増殖・分化制御系
- Principal Investigator
  
  山田真澄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Chiba University
クロマチン動態の差異に起因する造血幹細胞のサイトカイン応答パラドックスPrincipal Investigator
- Principal Investigator
  
  梅本晃正
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
造血幹細胞のサイトカイン応答を規定するクロマチン動態変化の制御Principal Investigator
- Principal Investigator
  
  梅本晃正
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kumamoto University
The maintenance of hematopoietic stem cells through tuning TPO responsePrincipal Investigator
- Principal Investigator
  
  Umemoto Terumasa
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kumamoto University
Energy metabolism-dependent selection of self-renewal and differnetiation in HSCsPrincipal Investigator
- Principal Investigator
  
  Umemoto Terumasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
Angiogenic machinery via concerted biomechanical control by blood flow pericyte
- Principal Investigator
  
  Nishiyama Koichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  University of Miyazaki
  Kumamoto University
Self-renewal capacity of hematopoietic stem cells and mitochondrial metabolism
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kumamoto University
IFNgamma-mediated regulation of hematopoeitc stem cells in stress hematopoiesisPrincipal Investigator
- Principal Investigator
  
  Umemoto Terumasa
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
AlphaVbeta3 integrin bidirectionally regulates hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Umemoto Terumasa
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Homeostasis of hematopoietic stem cells and its breakdown
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors2022
- Author(s)
  Tanaka Yosuke....Goyama Susumu、Komatsu Norio、Takaku Tomoiku、Kitamura Toshio
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 271-271
- DOI
  10.1038/s41467-021-27928-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03685, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-22K19539, KAKENHI-PROJECT-20H00537
[Journal Article] Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells2022
- Author(s)
  Takihara Yuji、Higaki Takumi、Yokomizo Tomomasa、Umemoto Terumasa、Ariyoshi Kazunori、Hashimoto Michihiro、Sezaki Maiko、Takizawa Hitoshi、Inoue Toshihiro、Suda Toshio、Mizuno Hidenobu
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 776-776
- DOI
  10.1038/s42003-022-03733-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-22K19549, KAKENHI-ORGANIZER-22H05092, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20H03289, KAKENHI-PROJECT-20K09774, KAKENHI-PLANNED-18H05492
[Journal Article] ATP citrate lyase controls hematopoietic stem cell fate and supports bone marrow regeneration2022
- Author(s)
  Umemoto Terumasa、Johansson Alban、Ahmad Shah Adil Ishtiyaq、Hashimoto Michihiro、Kubota Sho、Kikuchi Kenta、Odaka Haruki、Era Takumi、Kurotaki Daisuke、Sashida Goro、Suda Toshio
- Journal Title
  
  The EMBO Journal
  
  Volume: 41 Issue: 8 Pages: 1-20
- DOI
  10.15252/embj.2021109463
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-21K08421, KAKENHI-PROJECT-22K15660, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19K16263, KAKENHI-PROJECT-21K16272
[Journal Article] Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer2022
- Author(s)
  Fu Lingfeng、Yonemura Atsuko、Yasuda-Yoshihara Noriko、Umemoto Terumasa、Zhang Jun、Yasuda Tadahito、Uchihara Tomoyuki、Akiyama Takahiko、Kitamura Fumimasa、Yamashita Kohei、Okamoto Yuya、Bu Luke、Wei Feng、Hu Xichen、Liu Yang、Ajani Jaffer A.、Tan Patrick、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Gastric Cancer
  
  Volume: 25 Issue: 3 Pages: 542-557
- DOI
  10.1007/s10120-022-01283-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535
[Journal Article] Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates2021
- Author(s)
  Hashimoto Michihiro、Umemoto Terumasa、Nakamura-Ishizu Ayako、Matsumura Takayoshi、Yokomizo Tomomasa、Sezaki Maiko、Takizawa Hitoshi、Suda Toshio
- Journal Title
  
  Blood Advances
  
  Volume: 5 Issue: 6 Pages: 1594-1604
- DOI
  10.1182/bloodadvances.2020002410
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18J20690, KAKENHI-PROJECT-19J00952, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284
[Journal Article] Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation2021
- Author(s)
  Arima Yuichiro、Nakagawa Yoshiko、Takeo Toru、Ishida Toshifumi、Yamada Toshihiro、et al.
- Journal Title
  
  Nature Metabolism
  
  Volume: 3 Issue: 2 Pages: 196-210
- DOI
  10.1038/s42255-021-00342-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K08520, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-20H04108, KAKENHI-PROJECT-18K06817, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-19H04446, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K19519, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-18H02798, KAKENHI-PROJECT-19H01048
[Journal Article] A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity2020
- Author(s)
  Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Akiyoshi Hirayama, Ayako Nakamura-Ishizu, Terumasa Umemoto, Michihiro Hashimoto, Kunio Nagashima, Tomoyoshi Soga, Martin Lang , Laura S Schmidt , W Marston Linehan, Toshio Suda
- Journal Title
  
  Cell Reports
  
  Volume: 30 Issue: 6 Pages: 1823-1834
- DOI
  10.1016/j.celrep.2020.01.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-16H06276
[Journal Article] Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors.,2019
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Junichi Matsuo, Ryota Harai, Yoshihiko Kihara, Eri Nakamura, Norihiro Tada, Tomohiko Sato, Tomoiku Takaku, Akihiko Shimono, Hitoshi Takizawa, Naomi Nakagata, Seiichi Mori, Mineo Kurokawa, Daniel Tenen, Motomi Osato, Toshio Suda, and Norio Komatsu.
- Journal Title
  
  J Exp Med
  
  Volume: 216 Issue: 7 Pages: 1599-1614
- DOI
  10.1084/jem.20181399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-17K09958
[Journal Article] Hlf expression marks the developmental pathway for hematopoietic stem cells but not for erythroid-myeloid progenitors2019
- Author(s)
  Yokomizo T, Watanabe N, Umemoto T, Matsuo J, Harai R, Kihara Y, Koga S, Nakamura E, Tada N, Sato T, Takaku T, Shimono A, Takizawa H, Ogawa M, Nakagata N, Mori S, Kurokawa M, Tenen DG, Osato M,Suda T, Komatsu N
- Journal Title
  
  J Exp. Med.
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] High Mitochondrial Mass Is Associated With Reconstitution Capacity and Quiescence of Hematopoietic Stem Cells2019
- Author(s)
  Yuji Takihara, Ayako Nakamura-Ishizu, Darren Qiancheng Tan, Masahiro Fukuda, Takayoshi Matsumura, Mitsuhiro Endoh, Yuichiro Arima, Desmond Wai Loon Chin, Terumasa Umemoto, Michihiro Hashimoto, Hidenobu Mizuno, Toshio Suda
- Journal Title
  
  Blood Advances
  
  Volume: 3 Issue: 15 Pages: 2323-2327
- DOI
  10.1182/bloodadvances.2019032169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19H03688
[Journal Article] Discrimination of dormant and active hematopoietic stem cells by G0 markers reveals dormancy regulation by cytoplasmic calcium.2019
- Author(s)
  5.Fukushima T, Tanaka Y, Hamey FK, Chang CH, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, Kawabata KC, Fukuyama T, Umemoto T, Takubo K, Takizawa H, Goyama S, Ishihama Y, Honda H, Gottgens B, Kitamura T.
- Journal Title
  
  Cell Rep
  
  Volume: 29 Issue: 12 Pages: 4144-4158
- DOI
  10.1016/j.celrep.2019.11.061
- NAID
  120006892032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-18K19570
[Journal Article] Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation2018
- Author(s)
  3.Baba M, Endoh M, Ma W, Toyama H, Hirayama A, Nishikawa K, Takubo K, Hano H, Hasumi H, Umemoto T, Hashimoto M, Irie N, Esumi C, Kataoka M, Nakagata N, Soga T, Yao M, Kamba T, Minami T, Ishii M, and Suda T.
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 33 Issue: 10 Pages: 1785-1798
- DOI
  10.1002/jbmr.3477
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-18K18455, KAKENHI-PROJECT-18K19619, KAKENHI-PUBLICLY-17H05530, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K11020, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H03580
[Journal Article] Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency2018
- Author(s)
  Ito Naofumi、Katoh Kaoru、Kushige Hiroko、Saito Yutaka、Umemoto Terumasa、Matsuzaki Yu、Kiyonari Hiroshi、Kobayashi Daiki、Soga Minami、Era Takumi、Araki Norie、Furuta Yasuhide、Suda Toshio、Kida Yasuyuki、Ohta Kunimasa
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1634-1634
- DOI
  10.1038/s41598-018-20057-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07118, KAKENHI-PROJECT-16H04795, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-16K18553, KAKENHI-PROJECT-18K06264, KAKENHI-PLANNED-17H06410, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-16H05440
[Journal Article] Ca(2+)-mitochondria axis drives cell division in hematopoietic stem cells2018
- Author(s)
  Umemoto T, Hashimoto M, MatsumuraT, Nakamura-Ishizu A, Suda T
- Journal Title
  
  J Exp Med.
  
  Volume: 218(8) Issue: 8 Pages: 2097-2113
- DOI
  10.1084/jem.20180421
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-17K16190
[Journal Article] Thrombopoietin metabolically primes hematopoietic stem cells to megakaryocyte lineage differentiation2018
- Author(s)
  Nakamura-Ishizu N, Matsumura T, Stumpf PS, Umemoto T, Takizawa H, Takihara Y, O’Neil A, Majeed ABBA, MacArthur BD., Suda T
- Journal Title
  
  Cell Reports
  
  Volume: 25(7) Issue: 7 Pages: 1772-1785
- DOI
  10.1016/j.celrep.2018.10.059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-15KK0350, KAKENHI-PROJECT-18K08364
[Journal Article] Integrin αvβ3 enhances the suppressive effect of interferon‐γ on hematopoietic stem cells2017
- Author(s)
  Umemoto Terumasa、Matsuzaki Yu、Shiratsuchi Yoshiko、Hashimoto Michihiro、Yoshimoto Takayuki、Nakamura‐Ishizu Ayako、Petrich Brian、Yamato Masayuki、Suda Toshio
- Journal Title
  
  The EMBO Journal
  
  Volume: 36 Issue: 16 Pages: 2390-2403
- DOI
  10.15252/embj.201796771
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16190, KAKENHI-PROJECT-26221309
[Patent] 培地、製造方法、及び細胞製剤2023
- Inventor(s)
  梅本晃正
- Industrial Property Rights Holder
  梅本晃正
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-007156
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K19549
[Presentation] ミトコンドリア代謝とクロマチン動態に基づいた造血幹細胞の制御機構2022
- Author(s)
  梅本晃正、須田年生
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19549
[Presentation] ACLY-dependent coupling of metabolic state and chromatin accessibility regulates hematopoietic stem cell functions during bone marrow regeneration2022
- Author(s)
  Terumasa Umemoto, Alban Johansson, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Sho Kubota, Kenta Kikuchi, Haruki Odaka, Takumi Era, Daisuke Kurotaki, Goro Sashida, Toshio Suda
- Organizer
  第19回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-22K19549
[Presentation] The metabolic fitness corresponding to chromatin accessibility patterns is essential for hematopoietic stem cell regulations2021
- Author(s)
  Terumasa Umemoto, Alban Johansson, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Sho Kubota, Haruki Odaka, Takumi Era, Goro Sashida, Toshio Suda
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03688
[Presentation] 還元的グルタミン代謝を介した造血幹細胞制御2021
- Author(s)
  Terumasa Umemoto, Alban Johansson, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Sho Kubota, Haruki Odaka, Takumi Era, Goro Sashida, Toshio Suda
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03688
[Presentation] Reductive Glutamine metabolism regulates self-renew and differentiation in hematopoietic stem cells during bone marrow regeneration2020
- Author(s)
  Terumasa Umemoto
- Organizer
  JSPS Core-to-Core Program Virtual Mini Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03688
[Presentation] Reductive Glutamine metabolism regulates self-renew and differentiation in hematopoietic stem cells during bone marrow regeneration2020
- Author(s)
  Terumasa Umemoto
- Organizer
  JSPS Core-to-Core Program Virtual Mini Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22641
[Presentation] Low energy metabolism contributes to the maintenace of hematopoietic stem cells.2019
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda
- Organizer
  幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03688
[Presentation] Low energy metabolism contributes to the maintenace of hematopoietic stem cells.2019
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda
- Organizer
  幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22641
[Presentation] エネルギー代謝を介した造血幹細胞の維持機構2019
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PROJECT-19K22641
[Presentation] エネルギー代謝を介した造血幹細胞の維持機構2019
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PROJECT-19H03688
[Presentation] Ca2+-mitochondria pathway による造血幹細胞の分裂制御2018
- Author(s)
  梅本晃正、橋本倫拓、須田年生
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] 細胞内カルシウム-ミトコンドリア制御を介した造血幹細胞の分裂制御2018
- Author(s)
  梅本晃正、橋本倫拓、須田年生
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] Ca2+-Mitochondrial axis drives cell division in hematopoietic stem cells.2018
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda.
- Organizer
  第17回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] Mitochondria metabolism regulates the activation of hematopoietic stem cells2018
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda
- Organizer
  JSPS & NUS Joint 2nd symposium "New Horizons in Normal and Cancer Stem Cell Research"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] ミトコンドリア代謝変化による造血幹細胞の活性化制御機構2017
- Author(s)
  梅本晃正、松崎優、橋本倫拓、須田年生
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] ミトコンドリア代謝変化による造血幹細胞の活性化制御機構2017
- Author(s)
  梅本晃正、橋本倫拓、須田年生
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] Mitochondria metabolism regulates the activation of hematopoietic stem cells2017
- Author(s)
  Terumasa Umemoto, Michihiro Hashimoto, Toshio Suda
- Organizer
  The 46th ISEH annual scientific meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] Mitochondria metabolism regulates the activation of hematopoietic stem cells2017
- Author(s)
  Terumasa Umemoto, Yu Matsuzaki, Michihiro Hashimoto, Toshio Suda
- Organizer
  The 15th Stem Cell Research Symposium
- Data Source
  KAKENHI-PROJECT-17K16190
[Presentation] 周辺環境に依存する Integrin αvβ3 による造血幹細胞活性の制御2016
- Author(s)
  梅本　晃正
- Organizer
  平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
- Place of Presentation
  蓼科
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19560
[Presentation] Integrin αvβ3 exerts double-edged effects on hematopoietic stem cells in response to STAT1 status2016
- Author(s)
  Terumasa Umemoto, Yu matsuzaki, Junichi Furusawa, Takayuki Yoshimoto, Masayuki Yamato, Toshio Suda
- Organizer
  Singapore-Japan joint symposium
- Place of Presentation
  National University of Singapore
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19560
[Presentation] Integrin αvβ3 regulates long-term repopulating activity of hematopoietic stem cells through the double-edged influences.2016
- Author(s)
  Terumasa Umemoto, Yu matsuzaki, Junichi Furusawa, Takayuki Yoshimoto, Masayuki Yamato, Toshio Suda
- Organizer
  第15回幹細胞シンポジウム
- Place of Presentation
  淡路島
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19560
[Presentation] Integrin αvβ3 regulates long-term repopulating activity of hematopoietic stem cells through the double-edged influences.2016
- Author(s)
  Terumasa Umemoto, Yu matsuzaki, Junichi Furusawa, Takayuki Yoshimoto, Masayuki Yamato, Toshio Suda
- Organizer
  2nd Kumamoto IRCMS international symposium and 17th Kumamoto AIDA seminar
- Place of Presentation
  Kumamoto
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19560
[Presentation] Integrin avβ3による双方向的な造血幹細胞の制御2015
- Author(s)
  梅本　晃正
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Integrin αvβ3 による双方向的な造血幹細胞活性の制御2015
- Author(s)
  梅本晃正, 松崎優, 大和雅之, 古澤純一, 善本隆之, 須田年生
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K19560

1. SUDA Toshio (60118453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 馬場理也 (10347304)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Nishiyama Koichi (80398221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石津綾子 (10548548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 坂本比呂志 (00347014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 田久保圭誉 (50502788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 植村明嘉 (30373278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 瀧原祐史 (50640140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 井上俊洋 (00317025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 有馬勇一郎 (60706414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 水野秀信 (00567159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山田真澄 (30546784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三原田賢一 (40455366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中洋介 (10509087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOBAYASHI Daiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 南敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 横溝智雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 合山進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 多田昇弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 遠藤充浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 本田善一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 本田浩章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UMEMOTO TERUMASA 梅本 晃正

Umemoto Terumasa 梅本 晃正

Research Projects

Research Products

Co-Researchers

グルタミノリシスに依存しない造血幹細胞の自己複製分裂誘導機構Principal Investigator

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生体イメージングと網羅的解析によるミトコンドリア面からみた緑内障とその治療法探索

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「硬さ」を計測し操作する造血幹細胞の増殖・分化制御系

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クロマチン動態の差異に起因する造血幹細胞のサイトカイン応答パラドックスPrincipal Investigator

Principal Investigator

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造血幹細胞のサイトカイン応答を規定するクロマチン動態変化の制御Principal Investigator

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The maintenance of hematopoietic stem cells through tuning TPO responsePrincipal Investigator

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Energy metabolism-dependent selection of self-renewal and differnetiation in HSCsPrincipal Investigator

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Angiogenic machinery via concerted biomechanical control by blood flow pericyte

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Self-renewal capacity of hematopoietic stem cells and mitochondrial metabolism

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IFNgamma-mediated regulation of hematopoeitc stem cells in stress hematopoiesisPrincipal Investigator

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AlphaVbeta3 integrin bidirectionally regulates hematopoietic stem cellsPrincipal Investigator

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Homeostasis of hematopoietic stem cells and its breakdown

Principal Investigator

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[Journal Article] Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors2022

Author(s)

Journal Title

UMEMOTO TERUMASA 梅本晃正

Umemoto Terumasa 梅本晃正