FUJIWARA MAKOTO 藤原誠

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FUJIWARA Makoto 藤原誠

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Researcher Number	50625697
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院医学系研究科, 助教 2019 – 2021: 大阪大学, 歯学研究科, 助教 2015 – 2016: 大阪大学, 歯学研究科(研究院), 助教 2015: 大阪大学, 大学院医学系研究科, 助教 2015: 大阪大学, 歯学部附属病院, 助教 2011: 大阪大学, 医学系研究科, 大学院生 2011: 大阪大学, 医学部附属病院
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / 0904:Internal medicine of the bio-information integration and related fields / Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator 肥満 / 2型糖尿病 / 軟骨無形成症 / 脂肪細胞 / 骨細胞 / 骨芽細胞 / 小胞体ストレス / コラーゲン蓄積 / コラーゲン過修飾 / 骨形成不全症 / 疾患iPS細胞由来骨芽細胞 … More Except Principal Investigator … More 甲状腺ホルモントランスポーター / Wntシグナル / 骨石灰化 / 転写因子 / 骨細胞 / 線維芽細胞 / くる病 / スクレロスチン / 骨粗鬆症 / 骨代謝学 / 小児科学 / negative feedback / TαT1細胞 / TSH産生細胞 / 下垂体前葉 / ネガティブフィードバック / 甲状腺刺激ホルモン / 下垂体 / MCT10 / MCT8 / Allan-Herndon-Dudley症候群 / トランスレーショナルリサーチ / 乏突起膠細胞 / 成長障害 / 成長軟骨 / 軟骨細胞 / 臍帯血 / ビスフォスフォネート / 成長 / 骨 / klotho / FGF23 / カルシウム / リン Less

軟骨無形成症における特異的肥満の耐糖能機序の解明Principal Investigator
- Principal Investigator
  
  藤原誠
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Osaka University
Elucidation of the relationship between obesity and type 2 diabetes in achondroplasiaPrincipal Investigator
- Principal Investigator
  
  FUJIWARA MAKOTO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  Osaka University
小児骨系統疾患の病態解明を目指した疾患特異的ヒトiPS細胞の骨分化誘導法の確立Principal Investigator
- Principal Investigator
  
  藤原誠
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Identification and functional analysis of thyroid hormone transporters expressed in the pituitary
- Principal Investigator
  
  NAMBA Noriyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Elucidating mechanisms for coupling bone matrix formation with mineralization
- Principal Investigator
  
  Kubota Takuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Role of FGF23 in metabolic bone diseases
- Principal Investigator
  
  OZONO Keiichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Translational approach to identifying cell specific expression and function of thyroid hormone transporters
- Principal Investigator
  
  NAMBA Noriyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University

All 2016 2015 2014 2013 2011 Other

All Journal Article Presentation

[Journal Article] Successful induction of sclerostin in human-derived fibroblasts by 4 transcription factors and its regulation by parathyroid hormone, hypoxia, and prostaglandin E2.2016
- Author(s)
  Fujiwara M, Kubota T, Wang W, Ohata Y, Miura K, Kitaoka T, Okuzaki D, Namba N, Michigami T, Kitabatake Y, Ozono K.
- Journal Title
  
  Bone
  
  Volume: 85 Pages: 91-98
- DOI
  10.1016/j.bone.2016.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860858
[Journal Article] Two Japanese familial cases of Caffey disease with and without the common COL1A1 mutation and normal bone density, and review of the literature.2014
- Author(s)
  Taichi Kitaoka, Yoko Miyoshi, Noriyuki Namba, Kohji Miura, Takuo Kubota, Yasuhisa Ohata, Makoto Fujiwara, Masaki Takagi, Tomonobu Hasegawa, Harald Jüppner, Keiichi Ozono
- Journal Title
  
  European Journal of Pediatrics
  
  Volume: [Epub ahead of print] Issue: 6 Pages: 1-6
- DOI
  10.1007/s00431-013-2252-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461548, KAKENHI-PROJECT-25860858
[Journal Article] Serum Fibroblast Growth Factor 23 Is a Useful Marker to Distinguish Vitamin D-Deficient Rickets from Hypophosphatemic Rickets.2014
- Author(s)
  Kubota T, Kitaoka T, Miura K, Fujiwara M, Ohata Y, Miyoshi Y, Yamamoto K, Takeyari S, Yamamoto T, Namba N, Ozono K.
- Journal Title
  
  Hormone Research in Paediatrics
  
  Volume: [Epub ahead of print] Issue: 4 Pages: 1-7
- DOI
  10.1159/000357142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461548, KAKENHI-PROJECT-25860858
[Journal Article] Kitaoka T, Namba N, Miura K, Kubota T, Ohata Y, Fujiwara M, Hirai H, Yamamoto T, Ozono K.2011
- Author(s)
  Kitaoka T, Namba N, Miura K, Kubota T, Ohata Y, Fujiwara M, Hirai H, Yamamoto T, Ozono K.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 29(5) Pages: 598-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591319
[Presentation] スクレロスチンの発現は転写因子ATF3, KLF4, PAX4, SP7の導入によりヒト線維芽細胞で誘導され、 PTH及び低酸素培養による制御を受ける2015
- Author(s)
  藤原　誠, 大幡泰久, 北岡太一，窪田拓生, 北畠康司, 難波範行, 道上敏, 大薗　恵一
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25860858
[Presentation] MCT8異常症には停留精巣が高頻度に合併する2015
- Author(s)
  高桑　聖、難波範行、山本賢一、中山尋文、武鑓真司、藤原　誠、北岡太一、窪田拓生、大薗恵一
- Organizer
  第49回日本小児内分泌学会学術集会
- Place of Presentation
  タワーホール船堀, 東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] Defined Sets of Transcription Factors Induce the Expression of Functional Sclerostin in Human Dermal Fibroblasts and Its Expression Responds to Parathyroid Hormone, Hypoxia and Prostaglandin E2.2015
- Author(s)
  Makoto Fujiwara, Wei Wang, Taichi Kitaoka，Takuo Kubota, Yasuji Kitabatake, Noriyuki Namba，Toshimi Michigami, Keiichi Ozono
- Organizer
  Annual Meeting of American Society for Bone and Mineral Research 2015
- Place of Presentation
  Seattle, WA, USA
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860858
[Presentation] Cryptorchidism is commonly observed in Allan Herndon Dudley syndrome2015
- Author(s)
  Noriyuki Namba, Satoshi Takakuwa, Hirofumi Nakayama, Keiko Yamamoto, Makoto Fujiwara, Yasuhisa Ohata, Taichi Kitaoka, Takuo Kubota, Keiichi Ozono
- Organizer
  54th Annual ESPE (European Society for Paediatric Endocrinology) Meeting
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] 下垂体において甲状腺ホルモンnegative feedbackを担う甲状腺ホルモントランスポーターの検索2013
- Author(s)
  藤原誠、難波範行、川井正信、山本景子、三浦弘司、北岡太一、窪田拓生、大薗恵一
- Organizer
  第86回　日本内分泌学会学術総会
- Place of Presentation
  宮城県、仙台国際センター
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] Thyroid hormone transporter expression in the murine anterior pituitary lobe2013
- Author(s)
  Fujiwara M, Namba N, Kawai M, Yamamoto K, Miura K, Kitaoka T, Kubota T, Ozono K
- Organizer
  9th Joint Meeting of Paediatric Endocrinology
- Place of Presentation
  MiCo, Milan, Italy
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] A novel MCT8 mutation in a Japanese patient with Allan-Herndon-Dudley Syndrome2013
- Author(s)
  Dateki S, Haraguchi K, Sato T, Nakatomi A, Fujiwara M, Sakurai M, Namba N, Ozono K, Moriuchi H
- Organizer
  9th Joint Meeting of Paediatric Endocrinology
- Place of Presentation
  MiCo, Milan, Italy
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] 早期に診断しえたMCT8欠損症の一例2013
- Author(s)
  赤木幹弘、小川博子、矢野節子、藤原真須美、橋本達、櫻井舞子、藤原誠、難波範行、大薗恵一
- Organizer
  第51回　日本社会保険医学会総会
- Place of Presentation
  群馬県
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] 重度精神運動発達遅滞の精査で診断されたMonocarboxylate transporter 8異常症の2例2013
- Author(s)
  伊達木澄人、中富明子、原口康平、里龍晴、藤原誠、難波範行、大薗恵一、森内浩幸
- Organizer
  第47回　日本小児内分泌学会学術集会
- Place of Presentation
  東京都、浅草ビューホテル
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] Expression and functional analysis of thyroid hormone transporters in chondrocytes
- Author(s)
  Namba N, Abe S, Abe M, Fujiwara M, Aikawa T, Kogo M, Ozono K
- Organizer
  第30回　小児代謝性骨疾患研究会（Recent progress in pediatric bone disease）
- Place of Presentation
  大阪府、千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] SLC16A2遺伝子のexon3内に5塩基挿入の新規変異が同定されたMCT8異常症の１男児例
- Author(s)
  小野英利奈、大島早希子、今井祐之、落合幸勝、藤原誠、櫻井舞子、難波範行、大薗恵一、宮田市郎
- Organizer
  第48回日本小児内分泌学会学術集会
- Place of Presentation
  浜松
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461547
[Presentation] ヒト線維芽細胞にスクレロスチンを発現させるために必要な転写因子の同定
- Author(s)
  藤原誠，大幡泰久，三浦弘司，北岡太一，窪田拓生，北畠康司，難波範行，道上敏美，大薗恵一
- Organizer
  第32回　日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25860858
[Presentation] Sclerostin Expression can be Induced by Enforced Expression of Defined Transcription Factors in Human Fibroblasts
- Author(s)
  Fujiwara M，Wang W，Ohata Y，Miura K，Kitaoka T，Kubota T，Kitabatake Y，Namba N，Michigami T，Ozono K
- Organizer
  Annual Meeting of American Society for Bone and Mineral Research 2014
- Place of Presentation
  Houston, TX, USA
- Year and Date
  2014-09-12 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-25860858

1. NAMBA Noriyuki (10379076)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. OZONO Keiichi (20270770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MIURA Kohji (30625695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. MOHRI Ikuko (70399351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAWAI Masanobu (50598117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KITABATAKE Yasuji (80506494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Kubota Takuo (40629135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. ABE Sanae

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISLAM Mohammad Saiful

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 北岡太一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 川井正信(カワイマサノブ)

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

FUJIWARA MAKOTO 藤原 誠

FUJIWARA Makoto 藤原 誠

Research Projects

Research Products

Co-Researchers

軟骨無形成症における特異的肥満の耐糖能機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the relationship between obesity and type 2 diabetes in achondroplasiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

小児骨系統疾患の病態解明を目指した疾患特異的ヒトiPS細胞の骨分化誘導法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and functional analysis of thyroid hormone transporters expressed in the pituitary

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidating mechanisms for coupling bone matrix formation with mineralization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of FGF23 in metabolic bone diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Translational approach to identifying cell specific expression and function of thyroid hormone transporters

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Successful induction of sclerostin in human-derived fibroblasts by 4 transcription factors and its regulation by parathyroid hormone, hypoxia, and prostaglandin E2.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two Japanese familial cases of Caffey disease with and without the common COL1A1 mutation and normal bone density, and review of the literature.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Fibroblast Growth Factor 23 Is a Useful Marker to Distinguish Vitamin D-Deficient Rickets from Hypophosphatemic Rickets.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kitaoka T, Namba N, Miura K, Kubota T, Ohata Y, Fujiwara M, Hirai H, Yamamoto T, Ozono K.2011

Author(s)

Journal Title

Data Source

[Presentation] スクレロスチンの発現は 転写因子ATF3, KLF4, PAX4, SP7の導入により ヒト線維芽細胞で誘導され、 PTH及び低酸素培養による制御を受ける2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] MCT8異常症には停留精巣が高頻度に合併する2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Defined Sets of Transcription Factors Induce the Expression of Functional Sclerostin in Human Dermal Fibroblasts and Its Expression Responds to Parathyroid Hormone, Hypoxia and Prostaglandin E2.2015

Author(s)

FUJIWARA MAKOTO 藤原誠

FUJIWARA Makoto 藤原誠

[Presentation] スクレロスチンの発現は転写因子ATF3, KLF4, PAX4, SP7の導入によりヒト線維芽細胞で誘導され、 PTH及び低酸素培養による制御を受ける2015