Wakayama Kenji 若山顕治

Researcher Number	50646544
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2021: 北海道大学, 医学研究院, 客員研究員 2017: 北海道大学, 医学研究院, 特任助教 2016: 北海道大学, 医学研究科, 特任助教 2013 – 2015: 北海道大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator 移植 / 肝臓 / リゾリン脂質 / 臓器灌流 / リン脂質 / 脂肪酸 / ミトコンドリア / 脂肪滴 / 機械灌流 / 脂肪肝 … More / 肝移植 / 心臓 / 重水 / シャペロン / 心移植 / 抗酸化 / 酸化ストレス / 臓器保存 / 虚血再灌流 / 移植・再生医療 … More Except Principal Investigator 癌 / EB1 / 外科 / 肝細胞癌 / 転移 / 浸潤 / 糖鎖 Less

Exploration of the new method to stimulate protective protein function during machine perfusion of steatotic graftPrincipal Investigator
- Principal Investigator
  
  Wakayama Kenji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hokkaido University
Analysis of radioresistance in pancreatic cancer by EB1 expression and its molecular mechanism
- Principal Investigator
  
  Orimo Tatsuya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University
Analysis of alteration of N-glycan and invasiveness in hepatocellular carcinoma cell-lines
- Principal Investigator
  
  Kamiyama Toshiya
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University
Methodology of the protein expression in the cardiac graft outside the bodyPrincipal Investigator
- Principal Investigator
  
  Wakayama Kenji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University

All 2021 2020 2019 2017 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Hepatectomy Combined with Diaphragmatic Resection for Hepatocellular Carcinoma with Diaphragmatic Involvement: A Propensity Score-Matched Analysis2020
- Author(s)
  Orimo Tatsuya, Kamiyama Toshiya, Wakayama Kenji, Shimada Shingo, Nagatsu Akihisa, Asahi Yoh, Sakamoto Yuzuru, Kamachi Hirofumi, Taketomi Akinobu
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 27 Issue: 11 Pages: 4153-4163
- DOI
  10.1245/s10434-020-08754-6
- NAID
  120007160305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09088
[Journal Article] Imaging Mass Spectrometry Reveals the Changes in the Taurine Conjugates of Dihydroxycholanoic Acid During Hepatic Warm Ischemia and Reperfusion in a Rat Model2020
- Author(s)
  Shibata Kengo, Hayasaka Takahiro, Hashimoto Satsuki, Umemoto Kohei, Ishikawa Takahisa, Sakamoto Sodai, Kato Koichi, Shimada Shingo, Kawamura Norio, Wakayama Kenji, Kobayashi Nozomi, Hama Yuka, Fukai Moto, Shimamura Tsuyoshi, Taketomi Akinobu
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 52 Issue: 6 Pages: 1880-1883
- DOI
  10.1016/j.transproceed.2020.01.169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09088, KAKENHI-PROJECT-20K08974, KAKENHI-PROJECT-19K18018, KAKENHI-PROJECT-18H02873, KAKENHI-PROJECT-20H03737
[Journal Article] Role of Wnt5a in suppressing invasiveness of hepatocellular carcinoma via epithelial-mesenchymal transition2020
- Author(s)
  Wakizaka Kazuki, Kamiyama Toshiya, Wakayama Kenji, Orimo Tatsuya, Shimada Shingo, Nagatsu Akihisa, Kamachi Hirofumi, Yokoo Hideki, Fukai Moto, Kobayashi Nozomi, Mitsuhashi Tomoko, Taketomi Akinobu
- Journal Title
  
  Oncology Letters
  
  Volume: 20 Issue: 5 Pages: 1-9
- DOI
  10.3892/ol.2020.12131
- NAID
  120007132045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09088
[Journal Article] Heavy Water (D2O) Containing Preservation Solution Reduces Hepatic Cold Preservation and Reperfusion Injury in an Isolated Perfused Rat Liver (IPRL) Model2019
- Author(s)
  Shimada Shingo、Fukai Moto、Shibata Kengo、Sakamoto Sodai、Wakayama Kenji、Ishikawa Takahisa、Kawamura Norio、Fujiyoshi Masato、Shimamura Tsuyoshi、Taketomi Akinobu
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 8 Issue: 11 Pages: 1818-1829
- DOI
  10.3390/jcm8111818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09088, KAKENHI-PROJECT-19K18018, KAKENHI-PROJECT-19K18137, KAKENHI-PROJECT-19K24020, KAKENHI-PROJECT-16H05398, KAKENHI-PROJECT-18H02873, KAKENHI-PROJECT-16K19885, KAKENHI-PROJECT-17K10500
[Journal Article] Hydrogen sulfide augments survival signals in warm ischemia and reperfusion of the mouse liver.2015
- Author(s)
  Shimada S, Fukai M, Wakayama K, Ishikawa T, Kobayashi N, Kimura T, Yamashita K, Kamiyama T, Shimamura T, Taketomi A, Todo S
- Journal Title
  
  Surg Today
  
  Volume: 45 Pages: 892-903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861147
[Journal Article] Intra-arterial infusion of IA-call (R) combined with oral anticancer drugs for recurrent hepatocellular carcinoma after liver resection.2014
- Author(s)
  Wakayama K, Kamiyama T, Yokoo H, Kakisaka T, Orimo T, Tsuruga Y, Kamachi H, Soyama T, Sakuhara Y, Abo D, Taketomi A
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 41(12) Pages: 1503-1505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861147
[Journal Article] Hand-assisted laparoscopic splenectomy for sclerosing angiomatoid nodular transformation of the spleen complicated by chronic disseminated intravascular coagulation: a case report.2014
- Author(s)
  Kakisaka T, Kamiyama T, Yokoo H, Orimo T, Wakayama K, Tsuruga Y, Kamachi H, Harada T, Kato F, Yamada Y, Mitsuhashi T, Taketomi A.
- Journal Title
  
  Asian J Endosc Surg.
  
  Volume: 7(3) Issue: 3 Pages: 275-278
- DOI
  10.1111/ases.12116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861147
[Journal Article] Hydrogen sulfide augments survival signals in warm ischemia and reperfusion of the mouse liver.2014
- Author(s)
  Shimada S, Fukai M, Wakayama K, Ishikawa T, Kobayashi N, Kimura T, Yamashita K, Kamiyama T, Shimamura T, Taketomi A, Todo S.
- Journal Title
  
  Surg Today
  
  Volume: epub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861147
[Journal Article] 臓器保存液の現状と今後～単純冷保存は役割を終えたのか？2013
- Author(s)
  深井原, 島田慎吾, 若山顕治, 嶋村剛, 山下健一郎, 藤堂省, 武冨紹信
- Journal Title
  
  Organ Biology
  
  Volume: 20(2) Pages: 176-180
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] 新規抗酸化物質 3,5-dihydroxy-4-methoxybenzyl alcohol（DHMBA）は小腸上皮細胞の冷保存傷害を軽減する2021
- Author(s)
  深井原、柴田賢吾、坂本聡大、島田慎吾、加藤紘一、藤好真人、若山顕治、石川隆壽、川村典生、嶋村剛、武冨紹信
- Organizer
  第121回日本外科学会定期学術集会　2021.4.10 (SF-091-8) hybrid開催
- Data Source
  KAKENHI-PROJECT-19K09088
[Presentation] 心停止ドナー肝に対する機械灌流における水素ガスの有効性の検討2021
- Author(s)
  坂本聡大、深井原、柴田賢吾、島田慎吾、加藤紘一、藤好真人、若山顕治、石川隆壽、川村典生、嶋村剛、武冨紹信
- Organizer
  第121回日本外科学会定期学術集会 2021.4.8 (PS-026) hybrid開催
- Data Source
  KAKENHI-PROJECT-19K09088
[Presentation] 小腸冷保存中の酸素供給が抗酸化治療の有効性に与える影響の検討2020
- Author(s)
  10)深井原、柴田賢吾、坂本聡大、島田慎吾、加藤紘一、藤好真人、若山顕治、石川隆壽、川村典生、嶋村剛、武冨紹信
- Organizer
  第120回日本外科学会定期学術集会 (web開催)
- Data Source
  KAKENHI-PROJECT-19K09088
[Presentation] 生存シグナル増強を目指した機械灌流による肝グラフトの薬剤性コンディショニング法の探索2019
- Author(s)
  深井原、柴田賢吾, 島田慎吾, 石川隆壽, 若山顕治, 藤好直, 小林希, 加藤紘一, 早坂孝宏, 三野和宏, 川村典生, 嶋村剛，武冨紹信
- Organizer
  第119回日本外科学会定期学術集会, 大阪国際会議場
- Data Source
  KAKENHI-PROJECT-19K09088
[Presentation] 虚血再灌流傷害に対する水素ガスの作用点の探索2019
- Author(s)
  深井原, 柴田賢吾, 坂本聡大, 島田慎吾, 小林希, 石川隆壽, 若山顕治, 藤好真人, 川村典生, 嶋村剛, 武冨紹信
- Organizer
  第46回日本臓器保存生物医学会学術集会, ふくしま医療機器開発支援センター
- Data Source
  KAKENHI-PROJECT-19K09088
[Presentation] 網羅的糖鎖解析による肝細胞癌の浸潤能と糖鎖異常の検討2017
- Author(s)
  高橋秀徳, 神山俊哉, 柿坂達彦, 相山健, 島田慎吾, 若山顕治, 永生高弘, 折茂達也, 蒲池浩文, 横尾英樹, 西村紳一郎, 武冨紹信
- Organizer
  第 117回日本外科学会定期学術集会（パシフィコ横浜・神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-16K10561
[Presentation] Time course of autophagy and oxidative phosphorylation during hypothermic oxygenated conditions and subsequent re-warming in human renal tubular cell line (HK2).2015
- Author(s)
  Fukai M, Ishikawa T, Wakayama K, Shimada S, Fujiyoshi M, Kimura T, Yamashita K, Shimamura T, Taketomi A.
- Organizer
  17th Congress of the European Society for Organ Transplantation (ESOT)
- Place of Presentation
  SQUARE BRUSSELS MEETING CENTRE (Brussels, Belgium)
- Year and Date
  2015-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] 低温灌流時の酸化的リン酸化と細胞内シグナルの制御～尿細管上皮を用いた検討2015
- Author(s)
  深井原、島田慎吾、若山顕治、石川隆壽、山下健一郎、嶋村剛、武冨紹信
- Organizer
  第42回日本臓器保存生物医学会学術集会
- Place of Presentation
  いわて県民情報交流センター（岩手県盛岡市）
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] 低温酸素化体外灌流における水素ガスの肝保護効果2015
- Author(s)
  石川隆壽、深井原、島田慎吾、若山顕治、後藤了一、木村太一、大澤郁朗、山下健一郎、嶋村剛、武冨紹信.
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] ヒト肝細胞リソース樹立のための組織片処理法と培養条件の検討2015
- Author(s)
  深井原, 石川隆壽, 島田慎吾, 若山顕治, 柿坂達彦, 敦賀陽介, 折茂達也, 横尾英樹, 蒲池浩文, 神山俊哉, 山下健一郎, 嶋村剛, 武冨紹信
- Organizer
  第27回　代用臓器・再生医学研究会総会
- Place of Presentation
  北海道大学医学部学友会館フラテ (札幌市)
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] Signal transduction during hypothermic oxygenated conditions in human renal tubular cells.2015
- Author(s)
  Fukai M, Ishikawa T, Wakayama K, Shimada S, Kimura T, Yamashita K, Shimamura T, Taketomi A.
- Organizer
  14th Congress of the Asian Society of Transplantation (CAST)
- Place of Presentation
  Suntec Singapore Convention&Exhibition Centre (Suntec City,Singapore)
- Year and Date
  2015-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] 低温下でのエネルギー代謝とApoptosis, Autophagy2014
- Author(s)
  深井原，石川隆壽，島田慎吾，若山顕治，後藤了一、山下健一郎，嶋村剛，武冨紹信
- Organizer
  第41回　日本臓器保存生物医学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター (吹田市)
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] ヘリウムガスによる肝冷保存再灌流障害軽減の試み2014
- Author(s)
  石川隆壽，深井原，島田慎吾，若山顕治山下健一郎，嶋村剛，神山俊哉，藤堂省，武冨紹信
- Organizer
  第114回　日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2014-04-03
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] より良い灌流保存のためのより良い単純冷保存法～重水と水素ガスの新たな可能性2014
- Author(s)
  深井原，石川隆壽，島田慎吾，若山顕治山下健一郎，嶋村剛，神山俊哉，藤堂省，武冨紹信
- Organizer
  第114回　日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2014-04-03
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] Heavy Water and Hydrogen Gas Confer Protection Against Hepatic Cold Ischemia and Reperfusion Injury in Isolated Perfused Rat Liver2013
- Author(s)
  Shimada S, Fukai M, Wakayama K, Yamashita K, Taniguchi M, Suzuki T, Shimamura T, Kamiyama T, Furukawa F, Todo S, Taketomi A.
- Organizer
  American Transplant Congress 2013
- Place of Presentation
  Washington State Convention & Trade Center （Seattle, USA）
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] Heavy Water and Hydrogen Gas Ameliorates Cold Preservation and Reperfusion Injury in Rat Liver2013
- Author(s)
  Shimada S, Fukai M, Wakayama K, Yamashita K, Taniguchi M, Suzuki T, Shimamura T, Kamiyama T, Furukawa F, Todo S, Taketomi A.
- Organizer
  Congress of European Society for Organ Transplantation 2013
- Place of Presentation
  Austria Center Vienna（Vienna, Austria）
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] 低温下でエネルギー産生を賦活化させる新しい方法～有効性と普遍性
- Author(s)
  深井原, 若山顕治, 山下健一郎, 廣方玄太郎, 谷口雅彦, 古川博之, 島田慎吾, 小倉正臣, 鈴木友己, 嶋村剛, 尾崎倫孝, 神山俊哉, 藤堂省
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-25861147
[Presentation] より良い臓器灌流のための臓器保存法と再灌流時治療：重水、水素の可能性
- Author(s)
  深井原、島田慎吾、若山顕治、石川隆壽、山下健一郎、嶋村剛、武冨紹信
- Organizer
  第４０回　日本臓器保存生物医学会学術集会
- Place of Presentation
  東京医科大学病院臨床講堂（東京都）
- Data Source
  KAKENHI-PROJECT-25861147

1. Kamiyama Toshiya (80322816)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Orimo Tatsuya (80711861)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 島田慎吾 (40755576)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. 横尾英樹 (70399947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 西村紳一郎 (00183898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 武冨紹信 (70363364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 蒲池浩文 (60374237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 嶋村剛 (00333617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. 深井原 (60374344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. 木村太一 (90435959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Wakayama Kenji 若山 顕治

Research Projects

Research Products

Co-Researchers

Exploration of the new method to stimulate protective protein function during machine perfusion of steatotic graftPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of radioresistance in pancreatic cancer by EB1 expression and its molecular mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of alteration of N-glycan and invasiveness in hepatocellular carcinoma cell-lines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Methodology of the protein expression in the cardiac graft outside the bodyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hepatectomy Combined with Diaphragmatic Resection for Hepatocellular Carcinoma with Diaphragmatic Involvement: A Propensity Score-Matched Analysis2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Imaging Mass Spectrometry Reveals the Changes in the Taurine Conjugates of Dihydroxycholanoic Acid During Hepatic Warm Ischemia and Reperfusion in a Rat Model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Wnt5a in suppressing invasiveness of hepatocellular carcinoma via epithelial-mesenchymal transition2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Heavy Water (D2O) Containing Preservation Solution Reduces Hepatic Cold Preservation and Reperfusion Injury in an Isolated Perfused Rat Liver (IPRL) Model2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrogen sulfide augments survival signals in warm ischemia and reperfusion of the mouse liver.2015

Author(s)

Journal Title

Data Source

[Journal Article] Intra-arterial infusion of IA-call (R) combined with oral anticancer drugs for recurrent hepatocellular carcinoma after liver resection.2014

Author(s)

Journal Title

Data Source

[Journal Article] Hand-assisted laparoscopic splenectomy for sclerosing angiomatoid nodular transformation of the spleen complicated by chronic disseminated intravascular coagulation: a case report.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrogen sulfide augments survival signals in warm ischemia and reperfusion of the mouse liver.2014

Author(s)

Journal Title

Data Source

[Journal Article] 臓器保存液の現状と今後～単純冷保存は役割を終えたのか？2013

Author(s)

Journal Title

Data Source

[Presentation] 新規抗酸化物質 3,5-dihydroxy-4-methoxybenzyl alcohol（DHMBA）は小腸上皮 細胞の冷保存傷害を軽減する2021

Author(s)

Organizer

Data Source

[Presentation] 心停止ドナー肝に対する機械灌流における水素ガスの有効性の検討2021

Author(s)

Organizer

Data Source

[Presentation] 小腸冷保存中の酸素供給が抗酸化治療の有効性に与える影響の検討2020

Wakayama Kenji 若山顕治

[Presentation] 新規抗酸化物質 3,5-dihydroxy-4-methoxybenzyl alcohol（DHMBA）は小腸上皮細胞の冷保存傷害を軽減する2021