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Kamachi Hirofumi  蒲池 浩文

ORCIDConnect your ORCID iD *help
… Alternative Names

蒲池 浩文  カマチ ヒロフミ

KAMACHI Hirofumi  蒲池 浩文

蓮池 浩文  カマチ ヒロフミ

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Researcher Number 60374237
Other IDs
External Links
Affiliation (Current) 2022: 北海道大学, 医学研究院, 客員研究員
Affiliation (based on the past Project Information) *help 2022: 北海道大学, 医学研究院, 客員研究員
2017 – 2021: 北海道大学, 大学病院, 講師
2015: 北海道大学, 北海道大学病院, 講師
2014 – 2015: 北海道大学, 大学病院, 講師
2013: 北海道大学, 医学(系)研究科(研究院), 特任講師 … More
2013: 北海道大学, 大学院・医学研究科, 特任講師
2011 – 2013: 北海道大学, 医学(系)研究科(研究院), 特任助教
2011 – 2012: 北海道大学, 大学院・医学研究科, 特任助教
2006: 北海道大学, 大学院医学研究科, 特任助手
2004 – 2005: 北海道大学, 大学院・医学研究科, 寄附講座教員
2004: Hokkaido Univ., Grad.School of Med., Instructor, 大学院・医学研究科, 寄附講座・教員 Less
Review Section/Research Field
Principal Investigator
General surgery / Digestive surgery / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
General surgery / Digestive surgery / Basic Section 55020:Digestive surgery-related / Anesthesiology/Resuscitation studies / Laboratory medicine / General surgery
Keywords
Principal Investigator
不凍糖タンパク質 / 不糖タンパク質 / 膵島移植 / 凍結保存 / 低温保存 / 不凍タンパク質 / mesotherin / cancer / mesothelin / Mesothelin … More / リンパ管浸潤 / 癌幹細胞 / 膵癌 / 化学放射線療法 / エネルギー代謝 / 術前治療 / NACRT / ジェムシタビン / メトホルミン / 抗癌剤治療 / 放射線治療 … More
Except Principal Investigator
体性幹細胞 / 凍結保存 / 細胞移植 / 増殖能 / Nestin陽性 / 奇形腫形成能 / 多分化能 / 分化誘導 / nestin陽性 / 膵島移植 / 細胞融合 / 組織幹細胞 / 糖尿病 / 膵β細胞 / 膵ラ氏島移植 / 分子標的治療 / NF-κB / CD40 / Mesothelin / C-ERC/mesothelin / リンパ管浸潤 / 予後 / 大腸癌 / EMT / 浸潤・転移 / hCG β / hCGβ / HCGβ / 分子機能解析 / 肝不全治療 / ハイブリッド型人工肝臓 / 肝細胞移植 / 小肝細胞 / 肝再生 / 肝細胞倍数体 / 生分解性パターン化フィルム / 増殖 / 人工肝臓 / in vitro増殖 / 肝特異機能 / hepatic support / hybrid artificial liver / hepatocyte transplantation / small hepatocyte / hepatic regeneration / hepatocyte ploidy / biodegradable honeycomb patterned film / EB1 / 癌 / 膵癌 / バイオマーカー / exosome / circular RNA / COPZ1 Less
  • Research Projects

    (12 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (22 People)
  •  血中exosome内circRNA発現解析による膵癌の診断・予後関連マーカー探索

    • Principal Investigator
      柿坂 達彦
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Hokkaido University
  •  肝細胞癌におけるCOPZ1の非癌遺伝子依存性と分子標的薬治療への応用

    • Principal Investigator
      折茂 達也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Hokkaido University
  •  Study on regulation of energy metabolism and sensitivity to chemo / radiotherapy in cancer stem cellsPrincipal Investigator

    • Principal Investigator
      蒲池 浩文
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Hokkaido University
  •  Analysis of radioresistance in pancreatic cancer by EB1 expression and its molecular mechanism

    • Principal Investigator
      Orimo Tatsuya
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Hokkaido University
  •  Chorionic gonadotropin beta modulates epithelial-mesenchymal transition in human colorectal carcinoma metastasis

    • Principal Investigator
      Homma Shigenori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Hokkaido University
  •  Significance of Mesothelin expression in gastrointestinal cancer and relation with cancer malignancyPrincipal Investigator

    • Principal Investigator
      KAMACHI Hirofumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Hokkaido University
  •  Development of a new strategy for pancreatic islet transplantation by molecular targeting agents

    • Principal Investigator
      YAMASHITA Kenichiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Hokkaido University
  •  Mesothelin and CA 125 expression in digestive carcinoma

    • Principal Investigator
      SHIMAMURA Tsuyoshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Hokkaido University
  •  極洋の魚類より抽出された不凍タンパクを用いた膵島細胞の凍結保存法の開発Principal Investigator

    • Principal Investigator
      蒲池 浩文
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Hokkaido University
  •  体性幹細胞と膵島β細胞の細胞融合法の開発研究

    • Principal Investigator
      佐藤 直樹
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Hokkaido University
  •  免疫拒絶が生じない自己組織から作製する体性幹細胞樹立法開発の基礎的研究

    • Principal Investigator
      MATSUSHITA Michiaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hokkaido University
  •  Development of a hybrid artificial liver using small hepatocytes with high proliferative activity

    • Principal Investigator
      ATSUSHITA Michiaki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      HOKKAIDO UNIVERSITY

All 2015 2014 2013 2012 2004 2003 2002 Other

All Journal Article Presentation

  • [Journal Article] Importance of luminal membrane mesothelin expression in intraductal papillary mucinous neoplasms.2015

    • Author(s)
      Einama T, Kamachi H, Nishihara H, Homma S, Kanno H, Ishikawa M, Kawamata F, Konishi Y, Sato M, Tahara M, Okada K, Muraoka S, Kamiyama T, Taketomi A, Matsuno Y, Furukawa H, Todo S.
    • Journal Title

      Oncol Lett.

      Volume: 9(4) Pages: 1583-1589

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592017
  • [Journal Article] The Significance of Luminal Membrane Mesothelin Expression in Intraductal Papillary Mucinous Neoplasms2014

    • Author(s)
      Takahiro Einama, Hirofumi Kamachi, Hiroshi Nishihara, Shigenori Homma, Hiromi Kanno, Marin Ishikawa, Futoshi Kawamata, Yuji Konishi, Masanori Sato, Munenori Tahara, Kuniaki Okada, Shunji Muraoka, Toshiya Kamiyama, Akinobu Taketomi, Yoshihiro Matsuno, Satoru Todo
    • Journal Title

      Oncology Letters

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592017
  • [Journal Article] The efficacy of DHMEQ, a NF-κB inhibitor, in islet transplantation: II. Induction DHMEQ treatment ameliorates subsequent allo-immune responses, and permits a long-2013

    • Author(s)
      Watanabe M, Y amashita K, Kamachi H, Kuraya D, Koshizuka Y, Shibasaki S, Asahi Y, Ono H, Emoto S, Ogura M, Y oshida T, Ozaki M, Umezawa K, Matsushita M, T odo S
    • Journal Title

      Transplantation

      Volume: 96(5) Pages: 454-462

    • DOI

      10.1097/tp.0b013e31829b077f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390309
  • [Journal Article] The efficacy of DHMEQ, a NF-κB inhibitor, in islet transplantation: I. HMGB1 suppression by DHMEQ prevents early islet graft damage.2013

    • Author(s)
      Kuraya D, Watanabe M, Koshizuka Y, Ogura M, Y oshida T, Asahi Y, Kamachi H, Nakamura T, Harashima H, Ozaki M, Umezawa K, Matsushita M, Y amashita K, T odo S
    • Journal Title

      Transplantation

      Volume: 96(5) Pages: 445-53

    • DOI

      10.1097/tp.0b013e31829b0744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390309
  • [Journal Article] The efficacy of DHMEQ, a NF-κB inhibitor, in islet transplantation: II. Induction DHMEQ treatment ameliorates subsequent allo-immune responses, and permits a long-term islet allograft acceptance.2013

    • Author(s)
      Watanabe M, Y amashita K, Suzuki T, Kamachi H, Kuraya D, Koshizuka Y, Ogura M, Y oshida T, Aoyagi T, Fukumori D, Shimamura T, Okimura K, Maeta K, Miura T, Sakai F, T odo S
    • Journal Title

      Am J Transplant

      Volume: 13(8) Pages: 1976-1988

    • DOI

      10.1111/ajt.12330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390309
  • [Journal Article] Intracellular localization of mesothelin prescribes the patients' prognosis of extrahepatic bile duct cancer2012

    • Author(s)
      Kawamata F, Kamachi H, Homma S, Kamiyama T, Taketomi A et al
    • Journal Title

      Int J Oncol

      Volume: 41(6) Pages: 2109-2118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659289
  • [Journal Article] Luminal membrane expression of mesothelin is a prominent poor prognostic factor for gastric cancer2012

    • Author(s)
      Einama T, Kamachi H Kamiyama T, Taketomi A et al
    • Journal Title

      Br J Cancer Jun26

      Volume: 107(1) Pages: 137-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659289
  • [Journal Article] Induction of insulin-dependent diabetes mellitus by total pancreatectomy for pancreatic islet transplantation in cynomolgus monkeys2012

    • Author(s)
      Yoshida T, Suzuki T, Watanabe M, Yamashita K, Koshizuka Y, Kuraya D, Ogura H, Kamachi H, Matsushita M, Todo S
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: 19(6) Pages: 661-6

    • DOI

      10.1007/s00534-011-0485-3

    • NAID

      10031126982

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390309
  • [Journal Article] Liver tissue reconstruction in engineering of hepatocyte2004

    • Author(s)
      Matsushita M, Kamachi H, Matsumoto S, Morita T, Kobayashi S, Tamura H, Okubo H, Sato K, Tanaka M, Shimomura M, Todo S.
    • Journal Title

      Low Temp.Med. 30(2)

      Pages: 37-40

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370344
  • [Journal Article] Liver tissue reconstruction in tissue engineering2003

    • Author(s)
      Matsushita M, Kamachi H, Okubo H, Matsumoto S, Morita T, Kobayashi S, Sato K, Tanaka M, Shimomura M, Todo S.
    • Journal Title

      Surgery Frontier 10(3)

      Pages: 21-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370344
  • [Journal Article] Rat small hepatocytes for liver support : growth and metabolic activities in culture.2002

    • Author(s)
      Kamachi H, Matsushita M, Okubo H, Kawai T, Nishikawa K, Fujimoto T, Todo S.
    • Journal Title

      J Artif Organs. 5

      Pages: 24-29

    • NAID

      50001098696

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370344
  • [Journal Article] A novel method for faster formation of rat liver cell spheroids.2002

    • Author(s)
      Okubo H, Matsushita M, Kamachi M, Kawai T, Takahashi M, Fujimoto T, Nishikawa K, Todo S.
    • Journal Title

      Artif Organs. 26(6)

      Pages: 497-505

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370344
  • [Journal Article] Rat small hepatocytes for liver support : growth and metabolic activities in culture2002

    • Author(s)
      Kamachi H, et al.
    • Journal Title

      J Artif Organs 5

      Pages: 24-29

    • NAID

      50001098696

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370344
  • [Journal Article] Injuriousness of glycochenodeoxycholate and taurochenodeoxycholate to cultured hepatocytes.2002

    • Author(s)
      Noto H, Matsushita M, Nishikawa M, Okubo H, Kamachi H, Nishikawa K, Fujimoto T, Todo S.
    • Journal Title

      J Artif Organs. 5

      Pages: 30-36

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370344
  • [Presentation] Intraductal papillary mucinous neoplasms(IPMNs)におけるMesothelin発現様式の検討2014

    • Author(s)
      永生 高広, 蒲池 浩文, 西原 広史, 本間 重紀, 田原 宗徳, 岡田 邦明, 村岡 俊二, 神山 俊哉, 松野 吉宏, 谷口 雅彦, 古川 博之, 武富 紹信, 藤堂 省
    • Organizer
      第114回日本外科学会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都)
    • Data Source
      KAKENHI-PROJECT-24592017
  • [Presentation] Prevention of early graft loss by Proliferator-activated receptor-gamma agonist, pioglitazonoe, in canine islet autotransplantation2013

    • Author(s)
      Asahi Y , Y amashita K, Watanabe M, Ogura M, Ono H, Handly DE, Emoto S, Nagatsu A, Y oshida T , Koshizuka Y , Kamachi H, T aketomi A, T odo S
    • Organizer
      American Transplant Congress
    • Place of Presentation
      Seattle, U.S.A
    • Year and Date
      2013-05-20
    • Data Source
      KAKENHI-PROJECT-23390309
  • [Presentation] Roles of CD40-CD40L costimulatory pathway in pancreatic islet transplantation2013

    • Author(s)
      Koshizuka Y , Watanabe M, Suzuki T , Kamachi H, Ogura M, Yoshida T , Kuraya D, Fukumori D, Shimamura T , Okimura K, Maeta K, Miura T , Sakai F , T'odo S, Yamashita K
    • Organizer
      3rd ESOT Basic Science Meeting & 13th TTS Basic Science Symposium
    • Place of Presentation
      Paris, France
    • Year and Date
      2013-11-08
    • Data Source
      KAKENHI-PROJECT-23390309
  • [Presentation] 細胞内の局在に着目した肝外胆管癌におけるMesothelin発現の免疫組織学的検討2013

    • Author(s)
      川俣 太, 蒲池 浩文, 永生 高広, 西原 広史, 田原 宗徳, 神山 俊哉, 藤堂 省, 武冨 紹信
    • Organizer
      第25回日本肝胆膵外科学会
    • Place of Presentation
      ホテル東日本宇都宮(栃木)
    • Data Source
      KAKENHI-PROJECT-24592017
  • [Presentation] 大腸癌におけるMesothelin発現の生物学的意義の検討2012

    • Author(s)
      川俣太 西原広史 蒲池浩文 本間重紀 永生高広 高橋典彦 神山俊哉 藤堂省 武冨紹信
    • Organizer
      第23回日本消化器癌発生学会総会ワークショップ
    • Place of Presentation
      ルネッサンスリゾートナルト(徳島県)
    • Year and Date
      2012-11-15
    • Data Source
      KAKENHI-PROJECT-23659289
  • [Presentation] 大腸癌におけるMesothelin発現の免疫組織学的検討2012

    • Author(s)
      川俣太 蒲池浩文 本間重紀 永生高広 高橋典彦 西原広史 神山俊哉藤堂省 武冨紹信
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山国際会議場(富山県)
    • Year and Date
      2012-07-20
    • Data Source
      KAKENHI-PROJECT-23659289
  • [Presentation] 胆管癌におけるMesothelin発現の免疫組織学的検討2012

    • Author(s)
      川俣太 蒲池浩文 西原広史 永生高広 本間重紀 宮崎将也 田原宗徳 神山俊哉 藤堂省
    • Organizer
      第112回日本外科学会総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2012-04-13
    • Data Source
      KAKENHI-PROJECT-23659289
  • [Presentation] Taketomi Luminal membrane expression of mesothelin is significantly correlates with lymph node metastasis in colorectal cancer2012

    • Author(s)
      F. Kawamata, S. Homma, T. Einama, H.Nishihara, H. Kamachi, Y. Kato, T. Kamiyama, S. Todo, A.
    • Organizer
      第50回 Bennial Congress of theInternational Society of UniversityColon & Rectal Surgeons
    • Place of Presentation
      Palazzo della cultura e dei congressi(Italy)
    • Year and Date
      2012-06-24
    • Data Source
      KAKENHI-PROJECT-23659289
  • [Presentation] Prevention of early graft loss by Proliferator-activated receptor-gamma agonist, pioglitazonoe, in canine islet autotransplantation

    • Author(s)
      Asahi Y, Yamashita K,Watanabe M,Ogura M,Ono H,Handly DE, Emoto S, Nagatsu A, Yoshida T,Koshizuka Y, Kamachi H, Taketomi A, Todo S.
    • Organizer
      American Transplant Congress
    • Place of Presentation
      Washington State Convention & Trade Center (Seattle, U.S.A.)
    • Data Source
      KAKENHI-PROJECT-23390309
  • 1.  TODO Satoru (60136463)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 14 results
  • 2.  MATSUSHITA Michiaki (20250425)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 3.  KAMIYAMA Toshiya (80322816)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 10 results
  • 4.  Orimo Tatsuya (80711861)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  OZAKI Michitaka (80256510)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  NISHIHARA Hiroshi (50322805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 7.  YAMASHITA Kenichiro (00399940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  FURUKAWA Hiroyuki (70292026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  UMEZAWA Kazuo (70114402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHIMAMURA Tsuyoshi (00333617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Homma Shigenori (30533674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKAHASHI NORIHIKO (30399894)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKETOMI AKINOBU (70363364)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KAWAMURA HIDEKI (70645960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  佐藤 直樹 (70205946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  若山 顕治 (50646544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  横尾 英樹 (70399947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  深井 原 (60374344)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  柿坂 達彦 (40583092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  長田 直樹 (70416270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KAWAMATA FUTOSHI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  梅沢 一夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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