Miyamoto Takafumi 宮本崇史

… Alternative Names

Takafumi Miyamoto 宮本崇史

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Researcher Number	50740346
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help	2018 – 2025: 筑波大学, 医学医療系, 助教 2015 – 2016: 東京大学, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related / Medium-sized Section 38:Agricultural chemistry and related fields / Basic Section 44010:Cell biology-related / Tumor biology Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 48040:Medical biochemistry-related
Keywords	Principal Investigator 合成生物学 / オルガネラ / AMPK / p53 / 形態 / ExAPC / ミトコンドリア / 栄養学 / 時空間的活性ダイナミクス / アミノ酸 … More / 代謝 / バイオコンピューター / オルガネラの形態 / iCOM / 細胞内構造 / アルギニン / Akt / ｐ５３ / ASS1 … More Except Principal Investigator 細胞休眠 / 多時点的解析 / 低栄養ストレス / 分泌機構 / ライブセルイメージング / エクソソーム / 内分泌 / インスリン受容体基質（IRS） / RNA / インスリン様成長因子（IGF） / インスリン / 転写因子 / エネルギーセンサー / 脂肪肝炎 / 脂質 / 代謝制御 / 脂肪酸 / 脂質代謝 / ヘムオキシゲナーゼ / 消化管上皮バリア機能 / ヘムオキシゲナーゼ-1 / 一酸化炭素 / NRF2 / HSF1 / 一酸化炭素（CO) / ヘムオキシゲナーゼ-1 (HO-1) / 遊離ヘム / バリア障害 / タイトジャンクション Less

The molecular basis of adaptation to low nutritional stress in cancer cells and its application research
- Principal Investigator
  
  山本雄介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  National Cancer Center Japan
Regulation of insulin-like activities using signaling complexes formed by RNA and IRS-1.
- Principal Investigator
  
  高橋伸一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
超高解像度画像解析によるエクソソームの標的細胞内の情報リプログラミング機構の解明
- Principal Investigator
  
  山本雄介
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  National Cancer Center Japan
Fatty acid diversity and its sensing mechanism for metabolic control and therapeutic application
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
Integrated analysis for mitochondrial morphologyPrincipal Investigator
- Principal Investigator
  
  宮本崇史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  University of Tsukuba
Elucidation and manipulation of the regulatory mechanisms of cellular functions by metabolic codesPrincipal Investigator
- Principal Investigator
  
  Miyamoto Takafumi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  University of Tsukuba
Mechanism of intestinal barrier disruption caused by free heme causing aggravation of sepsis
- Principal Investigator
  
  Akagi Reiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yasuda Women's University
Integrated analysis of the multi-layered tumor suppressor system woven by p53 and AMPKPrincipal Investigator
- Principal Investigator
  
  Takafumi Miyamoto
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  University of Tsukuba
Programmable Biocomputing Systems for Organelle MorphologyPrincipal Investigator
- Principal Investigator
  
  宮本崇史
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  University of Tsukuba
Dissection of p53-mediated amino acid metabolismPrincipal Investigator
- Principal Investigator
  
  Miyamoto Takafumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia2024
- Author(s)
  Furuta Yasuhisa、Osaki Yoshinori、Nakagawa Yoshimi、Han Song-Iee、Araki Masaya、Shikama Akito、Ohuchi Nami、Yamazaki Daichi、Suzuki Hiroaki、Shimano Hitoshi et al.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 31 Issue: 9 Pages: 1304-1318
- DOI
  10.5551/jat.64579
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2024-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19886, KAKENHI-PROJECT-22K17769, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-23K23562
[Journal Article] Label-free imaging of cellular organization in living mammalian cells via external apodization phase-contrast microscopy2024
- Author(s)
  Sari Lay Nurhana、Miyamoto Takafumi et al.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.03.01.582671
- Open Access
- Data Source
  KAKENHI-PROJECT-23K23562
[Journal Article] 人類はこれからどのような食生活をしていくべきか2023
- Author(s)
  高橋伸一郎、宮本崇史、潮秀樹、山中大介、増田正人、伯野史彦、勝俣昌也、太田与洋
- Journal Title
  
  明日の食品産業
  
  Volume: 538 Pages: 42-49
- Data Source
  KAKENHI-PROJECT-23H00358
[Journal Article] <scp>GR‐KLF15</scp> pathway controls hepatic lipogenesis during fasting2023
- Author(s)
  Takeuchi Y, Murayama Y, Aita Y, Mehrazad Saber Z, Karkoutly S, Tao D, Katabami K, Ye C, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H, Yahagi N.
- Journal Title
  
  The FEBS Journal
  
  Volume: 291 Issue: 2 Pages: 259-271
- DOI
  10.1111/febs.16957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K13900, KAKENHI-PROJECT-23K15405, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-23K23562
[Journal Article] Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids2023
- Author(s)
  Han Song-Iee、Nakakuki Masanori、Nakagawa Yoshimi、Takeda Hiroyuki、Mizunoe Yuhei、Kainoh Kenta、Murayama Yuki、Aita Yuichi、Takeuchi Yoshinori、Osaki Yoshinori、Miyamoto Takafumi、Sekiya Motohiro、Matsuzaka Takashi、Yahagi Naoya、Sone Hirohito、Daitoku Hiroaki、Sato Ryuichiro、Kawano Hiroyuki、Shimano Hitoshi
- Journal Title
  
  PNAS Nexus
  
  Volume: 2 Issue: 11 Pages: 1-14
- DOI
  10.1093/pnasnexus/pgad351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K19886, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-22K17769, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Activity-dependent glassy cell mechanics Ⅰ: Mechanical properties measured with active microrheology2023
- Author(s)
  H. Ebata, K. Umeda, K. Nishizawa, W. Nagao, S. Inokuchi, Y. Sugino, T. Miyamoto, D. Mizuno
- Journal Title
  
  Biophysical Journal
  
  Volume: In press Issue: 10 Pages: 1781-1793
- DOI
  10.1016/j.bpj.2023.04.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H04848, KAKENHI-PROJECT-20H00128, KAKENHI-PROJECT-21H01048, KAKENHI-PROJECT-23K23562
[Journal Article] Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca2+ Allostasis Toward β-Cell Failure2023
- Author(s)
  Motomura K, Matsuzaka T, Shichino S, Ogawa T, Pan H, Nakajima T, Asano Y, Okayama T, Takeuchi T, Ohno H, Han SI, Miyamoto T, Takeuchi Y, Sekiya M, Sone H, Yahagi N, Nakagawa Y, Oda T, Ueha S, Ikeo K, Ogura A, Matsushima K, Shimano H.
- Journal Title
  
  Diabetes
  
  Volume: 73 Issue: 1 Pages: 75-92
- DOI
  10.2337/db23-0212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22K12043, KAKENHI-PROJECT-22K17769, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity2023
- Author(s)
  Saito K, Sekiya M, Kainoh K, Yoshino R, Hayashi A, Han SI, Araki M, Ohno H, Takeuchi Y, Tsuyuzaki T, Yamazaki D, Wanpei C, Hada L, Watanabe S, Paramita Adi Putri PI, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Miyamoto T, Matsuzaka T, Shimano H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104890-104890
- DOI
  10.1016/j.jbc.2023.104890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function2023
- Author(s)
  Sekiya M, Ma Y, Kainoh K, Saito K, Yamazaki D, Tsuyuzaki T, Chen W, Adi Putri PIP, Ohno H, Miyamoto T, Takeuchi Y, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Motomura K, Matsuzaka T, Murata K, Mizuno S, Takahashi S, Shimano H.
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 112914-112914
- DOI
  10.1016/j.celrep.2023.112914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Heat shock‐induced heme oxygenase‐1 expression in a mouse hepatoma cell line is dependent on <scp>HSF1</scp> and modified by <scp>NRF2</scp> and <scp>BACH1</scp>2022
- Author(s)
  Inouye Sachiye、Kubo Takanori、Miyamoto Takafumi、Iyoda Takuya、Okita Naoyuki、Akagi Reiko
- Journal Title
  
  Genes to Cells
  
  Volume: 27 Issue: 12 Pages: 719-730
- DOI
  10.1111/gtc.12986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11119, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562, KAKENHI-PROJECT-23K24297
[Journal Article] A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction.2022
- Author(s)
  Nakajima R, Sekiya M, Furuta Y, Miyamoto T, Sato M, Fukuda K, et, al.
- Journal Title
  
  Endocrinol Diabetes Metab Case Rep.
  
  Volume: 22 Pages: 0368-0368
- DOI
  10.1530/edm-22-0368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08072, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-20K08855, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-23K21443, KAKENHI-PROJECT-23K23562, KAKENHI-PROJECT-21K16262
[Journal Article] Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice2022
- Author(s)
  Okajima Yuka、Matsuzaka Takashi、Miyazaki Shun、Motomura Kaori、Ohno Hiroshi、Sharma Rahul、Shimura Takuya、Istiqamah Nurani、Han Song-iee、Mizunoe Yuhei、Osaki Yoshinori、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sone Hirohito、Miyamoto Takafumi、Aita Yuichi、Takeuchi Yoshinori、Sekiya Motohiro、Shimano Hitoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1868 Issue: 4 Pages: 166339-166339
- DOI
  10.1016/j.bbadis.2022.166339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562
[Journal Article] Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease.2022
- Author(s)
  Araki M, Nakagawa Y, Saito H, Yamada Y, Han SI, Mizunoe Y, Ohno H, Miyamoto T, Sekiya M, Matsuzaka T, Sone H, Shimano H.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 323 Issue: 6 Pages: 627-639
- DOI
  10.1152/ajpgi.00090.2022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K17769, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562, KAKENHI-PROJECT-23K24786
[Journal Article] ELOVL5-mediated fatty acid elongation promotes cellular proliferation and invasion in renal cell carcinoma2022
- Author(s)
  Nitta Satoshi、Kandori Shuya、Tanaka Ken、Sakka Shotaro、Siga Masanobu、Nagumo Yoshiyuki、Negoro Hiromitsu、Kojima Takahiro、Mathis Bryan J.、Shimazui Toru、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi、Nishiyama Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 8 Pages: 2738-2752
- DOI
  10.1111/cas.15454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09517, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562
[Journal Article] FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin2021
- Author(s)
  Takeuchi Yoshinori、Yahagi Naoya、Aita Yuichi、Mehrazad-Saber Zahra、Ho Man Hei、Huyan Yiren、Murayama Yuki、Shikama Akito、Masuda Yukari、Izumida Yoshihiko、Miyamoto Takafumi、Matsuzaka Takashi、Kawakami Yasushi、Shimano Hitoshi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 12 Pages: 103446-103446
- DOI
  10.1016/j.isci.2021.103446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-19K20175, KAKENHI-PROJECT-20K17505, KAKENHI-PROJECT-21K19064
[Journal Article] Protocol for rapid manipulation of mitochondrial morphology in living cells using inducible counter mitochondrial morphology (iCMM)2021
- Author(s)
  Miyamoto Takafumi、Han Song-Iee、Shimano Hitoshi
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 3 Pages: 100721-100721
- DOI
  10.1016/j.xpro.2021.100721
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21K19064
[Journal Article] CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF22021
- Author(s)
  Kainoh Kenta、Takano Ryo、Sekiya Motohiro、Saito Kenji、Sugasawa Takehito、Ma Yang、Murayama Yuki、Sugano Yoko、Osaki Yoshinori、Iwasaki Hitoshi、Takeuchi Yoshinori、Yahagi Naoya、Suzuki Hiroaki、Miyamoto Takafumi、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 562 Pages: 146-153
- DOI
  10.1016/j.bbrc.2021.05.069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma2021
- Author(s)
  Tanaka Ken、Kandori Shuya、Sakka Shotaro、Nitta Satoshi、Tanuma Kozaburo、Shiga Masanobu、Nagumo Yoshiyuki、Negoro Hiromitsu、Kojima Takahiro、Mathis Bryan、Shimazui Toru、Watanabe Makoto、Sato Taka-Aki、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi、Nishiyama Hiroyuki
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 2 Pages: 23-23
- DOI
  10.3892/or.2021.8234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] High protein diet-induced metabolic changes are transcriptionally regulated via KLF15-dependent and independent pathways2021
- Author(s)
  Mehrazad Saber Zahra、Takeuchi Yoshinori、Sawada Yoshikazu、Aita Yuichi、Ho Man Hei、Karkoutly Samia、Tao Duhan、Katabami Kyoka、Ye Chen、Murayama Yuki、Shikama Akito、Masuda Yukari、Izumida Yoshihiko、Miyamoto Takafumi、Matsuzaka Takashi、Sugasawa Takehito、Takekoshi Kazuhiro、Kawakami Yasushi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 582 Pages: 35-42
- DOI
  10.1016/j.bbrc.2021.10.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-19K20175, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Starvation‐induced transcription factor CREBH negatively governs body growth by controlling GH signaling2021
- Author(s)
  Nakagawa Yoshimi、Kumagai Kae、Han Song‐iee、Mizunoe Yuhei、Araki Masaya、Mizuno Seiya、Ohno Hiroshi、Matsuo Kazuya、Yamada Yasunari、Kim Jun‐dal、Miyamoto Takafumi、Sekiya Motohiro、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Takahashi Satoru、Sone Hirohito、Shimano Hitoshi
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 6 Pages: 21663-21663
- DOI
  10.1096/fj.202002784rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05429, KAKENHI-PROJECT-19K07095, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-21K19064
[Journal Article] The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis2021
- Author(s)
  Sekiya Motohiro、Kainoh Kenta、Sugasawa Takehito、Yoshino Ryunosuke、Hirokawa Takatsugu、Tokiwa Hiroaki、Nakano Shogo、Nagatoishi Satoru、Tsumoto Kouhei、Takeuchi Yoshinori、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-19
- DOI
  10.1038/s41467-021-26638-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-20H02531
[Journal Article] Rapid manipulation of mitochondrial morphology in a living cell with iCMM2021
- Author(s)
  Miyamoto Takafumi、Uosaki Hideki、Mizunoe Yuhei、Han Song-Iee、Goto Satoi、Yamanaka Daisuke、Masuda Masato、Yoneyama Yosuke、Nakamura Hideki、Hattori Naoko、Takeuchi Yoshinori、Ohno Hiroshi、Sekiya Motohiro、Matsuzaka Takashi、Hakuno Fumihiko、Takahashi Shin-Ichiro、Yahagi Naoya、Ito Koichi、Shimano Hitoshi
- Journal Title
  
  Cell Reports Methods
  
  Volume: 1 Issue: 4 Pages: 100052-100052
- DOI
  10.1016/j.crmeth.2021.100052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K16536, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-19KK0219, KAKENHI-PROJECT-23K23562
[Journal Article] Heme oxygenase-1 induction by heat shock in rat hepatoma cell line is regulated by the coordinated function of HSF1, NRF2 and BACH12021
- Author(s)
  Akagi Reiko、Kubo Takanori、Hatori Yuta、Miyamoto Takafumi、Inouye Sachiye
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 4 Pages: 501-510
- DOI
  10.1093/jb/mvab065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05703, KAKENHI-PROJECT-19K07359, KAKENHI-PROJECT-21K19064
[Journal Article] Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl‐Chain Length and Hepatic Insulin Sensitivity in Mice2020
- Author(s)
  Matsuzaka T、Kuba M、Koyasu S、Yamamoto Y、Motomura K、Arulmozhiraja S、Ohno H、Sharma R、Shimura T、Okajima Y、Han SI、Aita Y、Mizunoe Y、Osaki Y、Iwasaki H、Yatoh S、Suzuki H、Sone H、Takeuchi Y、Yahagi N、Miyamoto T、Sekiya M、Nakagawa Y、Ema M、Takahashi S、Tokiwa H、Shimano H
- Journal Title
  
  Hepatology
  
  Volume: 71 Issue: 5 Pages: 1609-1625
- DOI
  10.1002/hep.30953
- NAID
  120007132717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20175, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K21611, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18K06206
[Journal Article] Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT12020
- Author(s)
  Ma Yang、Sekiya Motohiro、Kainoh Kenta、Matsuda Takaaki、Iwasaki Hitoshi、Osaki Yoshinori、Sugano Yoko、Suzuki Hiroaki、Takeuchi Yoshinori、Miyamoto Takafumi、Yahagi Naoya、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Issue: 2 Pages: 354-360
- DOI
  10.1016/j.bbrc.2019.12.070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-18K06206
[Journal Article] ROCK 1 as a new player in the regulation of hepatic lipogenesis2019
- Author(s)
  Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 5 Pages: 1165-1167
- DOI
  10.1111/jdi.13051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PUBLICLY-18H04854, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18K19724
[Journal Article] Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex2019
- Author(s)
  Murayama Yuki, Takafumi Miyamoto, et al.
- Journal Title
  
  FEBS Letters
  
  Volume: 593 Issue: 4 Pages: 423-432
- DOI
  10.1002/1873-3468.13328
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17K12895, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-17K00846
[Journal Article] Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism2019
- Author(s)
  Sharma Rahu, Takafumi Miyamoto, et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5169-5169
- DOI
  10.1038/s41598-019-41631-1
- NAID
  120007133465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PROJECT-18K19724, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] Cellular Application of Genetically Encoded Sensors and Impeders of AMPK2018
- Author(s)
  Miyamoto Takafumi、Rho Elmer、Kim Allen、Inoue Takanari
- Journal Title
  
  Methods Mol Biol.
  
  Volume: - Pages: 255-272
- DOI
  10.1007/978-1-4939-7598-3_17
- ISBN
  9781493975976, 9781493975983
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PUBLICLY-18H04854
[Journal Article] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p532017
- Author(s)
  Miyamoto T, Lo PHY, Saichi N, Ueda K, Hirata M, Tanikawa C, Matsuda K.
- Journal Title
  
  Science Advances
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18397
[Patent] オルガネラの形態操作方法、オルガネラ形態変化用キット、オルガネラ形態操作のための細胞構成物質を使用した論理回路、およびアクチュエータータンパク質2019
- Inventor(s)
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Holder
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-211266
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06206
[Patent] オルガネラの形態操作方法、オルガネラ形態変化用キット、オルガネラ形態操作のための細胞構成物質を使用した論理回路、およびアクチュエータータンパク質2019
- Inventor(s)
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Holder
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-211266
- Filing Date
  2019
- Data Source
  KAKENHI-PUBLICLY-18H04854
[Presentation] SREBP-1aによる脂質合成の制御と食餌誘導性脂肪肝炎の病態2023
- Author(s)
  荒木　雅弥、韓　松伊、大崎　芳典、松坂　賢、矢作　直也、関谷　元博、宮本　崇史、中川　嘉、島野　仁
- Organizer
  第55回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] Rapid Manipulation of Mitochondrial Morphology in a Living Cell with iCMM2023
- Author(s)
  Takafumi Miyamoto
- Organizer
  Gordon Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23562
[Presentation] Rapid Manipulation of Mitochondrial Morphology in a Living Cell with iCMM2023
- Author(s)
  Takafumi Miyamoto
- Organizer
  Gordon Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19064
[Presentation] イメージングメタアナリシスの現状と課題2022
- Author(s)
  宮本崇史
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19064
[Presentation] 情報因子としてのオルガネラ形態に対する理解と制御2022
- Author(s)
  宮本崇史
- Organizer
  第19回糖鎖科学コンソーシアムシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K19064
[Presentation] 情報因子としてのオルガネラ形態に対する理解と制御2022
- Author(s)
  宮本崇史
- Organizer
  第19回糖鎖科学コンソーシアムシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K23562
[Presentation] イメージングメタアナリシスの現状と課題2022
- Author(s)
  宮本崇史
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23562
[Presentation] ラットHeme oxygenase-1の熱ショック応答～HSF1、NRF2、BACH1による転写調節～2021
- Author(s)
  赤木玲子、久保貴紀、羽鳥勇太、宮本崇史、井上幸江
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07359
[Presentation] 抗酸化酵素ヘムオキシゲナーゼ-１（HO-1）の熱ショック応答機構2021
- Author(s)
  井上幸江、伊豫田拓也、沖田直之、宮本崇史、久保貴紀、坂本祐美、赤木玲子
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07359
[Presentation] Alteration of the HO-1 induction in an HL60 cell line by differentiation2020
- Author(s)
  Sachiye Inouye, Takuya Iyoda, Naoyuki Okita, Takafumi Miyamoto, Yoichi Mizukami, Reiko Akagi
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07359
[Presentation] NIS.aiを用いた非染色・非侵襲的な可視化技術の開発2020
- Author(s)
  宮本崇史
- Organizer
  第126回日本解剖学会総会・全国学術集会　第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06206
[Presentation] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p532019
- Author(s)
  Takafumi Miyamoto
- Organizer
  Gordon Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206
[Presentation] 細胞機能を自在に制御する技術の開発2019
- Author(s)
  宮本崇史
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06206
[Presentation] 細胞機能を自在に制御する技術の開発2019
- Author(s)
  宮本崇史
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04854
[Presentation] マウス膵ベータ細胞MIN6のインスリン分泌に及ぼす遊離ヘムの作用2019
- Author(s)
  井上幸江、沖田直之、伊豫田拓也、宮本崇史、赤木玲子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07359
[Presentation] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p532019
- Author(s)
  Takafumi Miyamoto
- Organizer
  Gordon Research Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04854
[Presentation] 生物情報へのハッキングによる細胞操作技術の開発2019
- Author(s)
  Takafumi Miyamoto
- Organizer
  形態解析ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-18K06206
[Presentation] Hacking a living cell2018
- Author(s)
  Takafumi Miyamoto
- Organizer
  第10回光塾
- Invited
- Data Source
  KAKENHI-PROJECT-18K06206
[Presentation] オルガネラの形態制御法iCOMの開発2018
- Author(s)
  Takafumi Miyamoto
- Organizer
  第27回日本バイオイメージング学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06206
[Presentation] Integrated OMICS analysis identifies ASS1 as a novel p53 target that modulates Akt signaling2016
- Author(s)
  Takafumi Miyamoto
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K18397
[Presentation] Integrated OMICS analysis identifies ASS1 as a novel p53 target that modulates Akt signaling2016
- Author(s)
  Takafumi Miyamoto
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18397
[Presentation] Identification of a novel mechanism underlying p53-mediated amino acid metabolism2015
- Author(s)
  宮本崇史
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K18397

1. 山本雄介 (60768117)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 高橋伸一郎 (00197146)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Akagi Reiko (50150967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 井上幸江 (60159978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 北澤健生 (70791490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 久保貴紀 (90435751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 島野仁 (20251241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 大野博 (20847909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 関谷元博 (50420245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 松坂賢 (70400679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. 伯野史彦 (30282700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 片岡直行 (60346062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 豊島由香 (70516070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 増田正人 (60708543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中山淳 (30801237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 西田奈央 (80737114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OKITA Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. FUKUDA Kuniaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 武内謙憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
20. 韓松伊

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. 神鳥周也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 佐藤隆一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 水野大介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 金俊達

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 會田雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 中川嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 新田聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyamoto Takafumi 宮本 崇史

Takafumi Miyamoto 宮本 崇史

Research Projects

Research Products

Co-Researchers

The molecular basis of adaptation to low nutritional stress in cancer cells and its application research

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Regulation of insulin-like activities using signaling complexes formed by RNA and IRS-1.

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超高解像度画像解析によるエクソソームの標的細胞内の情報リプログラミング機構の解明

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Fatty acid diversity and its sensing mechanism for metabolic control and therapeutic application

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Integrated analysis for mitochondrial morphologyPrincipal Investigator

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Elucidation and manipulation of the regulatory mechanisms of cellular functions by metabolic codesPrincipal Investigator

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Mechanism of intestinal barrier disruption caused by free heme causing aggravation of sepsis

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Integrated analysis of the multi-layered tumor suppressor system woven by p53 and AMPKPrincipal Investigator

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Programmable Biocomputing Systems for Organelle MorphologyPrincipal Investigator

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Dissection of p53-mediated amino acid metabolismPrincipal Investigator

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[Journal Article] Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia2024

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[Journal Article] Label-free imaging of cellular organization in living mammalian cells via external apodization phase-contrast microscopy2024

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[Journal Article] 人類はこれからどのような食生活をしていくべきか2023

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Miyamoto Takafumi 宮本崇史

Takafumi Miyamoto 宮本崇史