Riku Koichi 陸雄一

… Alternative Names

Riku Yuichi 陸雄一

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Researcher Number	50748382
Other IDs	https://orcid.org/0000-0002-6493-8976
Affiliation (Current)	2025: 愛知医科大学, 加齢医科学研究所, 講師
Affiliation (based on the past Project Information) *help	2025: 愛知医科大学, 加齢医科学研究所, 講師 2023: 愛知医科大学, 加齢医科学研究所, 講師 2022 – 2023: 愛知医科大学, 分子医科学研究所, 講師 2020 – 2021: 愛知医科大学, 付置研究所, 助教 2015 – 2016: 名古屋大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology Except Principal Investigator Basic Section 52020:Neurology-related / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator TDP-43 / パーキンソン症候群 / 認知症 / ALS / タウオパチー / 神経変性疾患 / 剖検 / 筋萎縮性側索硬化症 / シナプス / tau … More / 前頭側頭型認知症 / 剖検脳 / 線条体 / 前頭側頭葉変性症 … More Except Principal Investigator iPS細胞 / ALS / 疾患レジストリ / 神経病理解析 / 筋萎縮性側索硬化症 Less

Clinico-genomic diversity and relationship between iPS cell phenotypes and neuropathologic findings in sporadic amyotrophic lateral sclerosis
- Principal Investigator
  
  熱田直樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Aichi Medical University
Investigation of mechanistic links between tauopathies and TDP-43 proteinopathiesPrincipal Investigator
- Principal Investigator
  
  陸雄一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Aichi Medical University
Elucidating the heterogeneity of amyotrophic lateral sclerosis by neuropathological analysis linked to clinical genomic information
- Principal Investigator
  
  熱田直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Aichi Medical University
Loss of hippocampal synapses in FTLD: autopsy-based studyPrincipal Investigator
- Principal Investigator
  
  Riku Yuichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Aichi Medical University
Postmortem investigations on pathological and diagnostic biomarkers of frontotemporal lobar degenerationPrincipal Investigator
- Principal Investigator
  
  Riku Yuichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University

All 2023 2022 2021 2020 2017 2015

All Journal Article Presentation Book

[Book] 認知症の病態理解2017
- Author(s)
  陸雄一
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K19483
[Journal Article] Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration2022
- Author(s)
  Riku Yuichi、Iwasaki Yasushi、Ishigaki Shinsuke、Akagi Akio、Hasegawa Masato、Nishioka Kenya、Li Yuanzhe、Riku Miho、Ikeuchi Takeshi、Fujioka Yusuke、Miyahara Hiroaki、Sone Jun、Hattori Nobutaka、Yoshida Mari、Katsuno Masahisa、Sobue Gen
- Journal Title
  
  Brain
  
  Volume: - Issue: 8 Pages: 2769-2784
- DOI
  10.1093/brain/awac091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16586, KAKENHI-PROJECT-20K16182, KAKENHI-PROJECT-21K07283, KAKENHI-PROJECT-21K15622, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K21410
[Journal Article] Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration2021
- Author(s)
  Riku Yuichi、Seilhean Danielle、Duyckaerts Charles、Boluda Susana、Iguchi Yohei、Ishigaki Shinsuke、Iwasaki Yasushi、Yoshida Mari、Sobue Gen、Katsuno Masahisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 8 Pages: 3843-3843
- DOI
  10.3390/ijms22083843
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16586, KAKENHI-PROJECT-20H03589, KAKENHI-PROJECT-23K21410
[Journal Article] Multiple system atrophy variant with severe hippocampal pathology2021
- Author(s)
  Ando Takashi、Riku Yuichi、Akagi Akio、et al.
- Journal Title
  
  Brain Pathology
  
  Volume: 32 Issue: 1
- DOI
  10.1111/bpa.13002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16586, KAKENHI-PROJECT-18H02739
[Journal Article] Reappraisal of the anatomical spreading and propagation hypothesis about TDP-43 aggregation in amyotrophic lateral sclerosis and frontotemporal lobar degeneration2020
- Author(s)
  Yuichi Riku
- Journal Title
  
  Neuropathology
  
  Volume: 40 Issue: 5 Pages: 426-435
- DOI
  10.1111/neup.12644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16586
[Journal Article] Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2017
- Author(s)
  Riku Y., Watanabe H., Yoshida M., Mimuro M., Iwasaki Y., Masuda M., Ishigaki S., Katsuno M., Sobue G.
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: in press Issue: 8 Pages: 801-811
- DOI
  10.1093/jnen/nlw053
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-15K19483, KAKENHI-PROJECT-15K09310, KAKENHI-ORGANIZER-26117001
[Presentation] Mechanistic links between tauopathy and TDP-43 proteinopathy2023
- Author(s)
  Yuichi Riku
- Organizer
  日本神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06935
[Presentation] Mechanistic links between tauopathy and TDP-43 proteinopathy2023
- Author(s)
  Yuichi Riku
- Organizer
  日本神経病理学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06935
[Presentation] Mechanistic links between tauopathy and TDP-43 proteinopathy2023
- Author(s)
  Yuichi Riku
- Organizer
  神経難病研究センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K06935
[Presentation] TDP-43 pathology of spinal cord in tau-related neurodegenerati ve disorders2021
- Author(s)
  陸　雄一
- Organizer
  日本神経学会　第62回学術総会
- Data Source
  KAKENHI-PROJECT-20K16586
[Presentation] TDP-43 pathology of spinal cord in tau-related neurodegenerative disorders2021
- Author(s)
  Yuichi Riku
- Organizer
  日本神経学会
- Data Source
  KAKENHI-PROJECT-20K16586
[Presentation] Reappraisal of the TDP-43 propagation hypothesis in amyotrophic lateral sclerosis and frontotemporal lobar degeneration2020
- Author(s)
  Yuichi Riku
- Organizer
  日本神経病理学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16586
[Presentation] INVOLVEMENT OF STRIATAL PROJECTION SYSTEM IN FRONTOTEMPORAL DEMENTIA AND AMYOTROPHIC LATERAL SCLEROSIS.2015
- Author(s)
  Yuichi Riku
- Organizer
  Brainconnects
- Place of Presentation
  名古屋大学野依記念学術交流館(愛知県名古屋市)
- Year and Date
  2015-07-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19483
[Presentation] 皮質-線条体系はTDP-43に関連した前頭側頭葉変性症で系統的に障害される2015
- Author(s)
  陸雄一、渡辺宏久、吉田眞理，三室マヤ、岩崎靖、桝田道人、勝野雅央、石垣診祐、祖父江元
- Organizer
  第56回日本神経病理学会総会
- Place of Presentation
  九州大学医学部百年講堂(福岡県福岡市)
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-15K19483

1. 熱田直樹 (90547457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 中村亮一 (80723030)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 祖父江元 (20148315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 藤内玄規 (00748353)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 道勇学 (90293703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 勝野雅央 (50402566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. WATANABE Hirohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. TANABE hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Riku Koichi 陸 雄一

Riku Yuichi 陸 雄一

Research Projects

Research Products

Co-Researchers

Clinico-genomic diversity and relationship between iPS cell phenotypes and neuropathologic findings in sporadic amyotrophic lateral sclerosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of mechanistic links between tauopathies and TDP-43 proteinopathiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the heterogeneity of amyotrophic lateral sclerosis by neuropathological analysis linked to clinical genomic information

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Loss of hippocampal synapses in FTLD: autopsy-based studyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Postmortem investigations on pathological and diagnostic biomarkers of frontotemporal lobar degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 認知症の病態理解2017

Author(s)

Publisher

Data Source

[Journal Article] Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiple system atrophy variant with severe hippocampal pathology2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reappraisal of the anatomical spreading and propagation hypothesis about TDP-43 aggregation in amyotrophic lateral sclerosis and frontotemporal lobar degeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43&#8201;kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mechanistic links between tauopathy and TDP-43 proteinopathy2023

Author(s)

Organizer

Data Source

[Presentation] Mechanistic links between tauopathy and TDP-43 proteinopathy2023

Author(s)

Organizer

Data Source

[Presentation] Mechanistic links between tauopathy and TDP-43 proteinopathy2023

Author(s)

Organizer

Data Source

[Presentation] TDP-43 pathology of spinal cord in tau-related neurodegenerati ve disorders2021

Author(s)

Organizer

Data Source

Riku Koichi 陸雄一

Riku Yuichi 陸雄一

[Journal Article] Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2017