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Nakajima-Takagi Yaeko  中島 やえ子

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中島 やえ子  ナカジマ ヤエコ

NAKAJIMA Yaeko  中島 やえ子

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Researcher Number 50749497
Affiliation (Current) 2025: 東京大学, 医科学研究所, 助教
Affiliation (based on the past Project Information) *help 2020 – 2023: 東京大学, 医科学研究所, 助教
2016 – 2018: 千葉大学, 大学院医学研究院, 特任助教
2015: 千葉大学, 医学(系)研究科(研究院), 日本学術振興会特別研究員RPD
2015: 千葉大学, 大学院医学研究院, 日本学術振興会特別研究員RPD
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Hematology
Except Principal Investigator
Hematology
Keywords
Principal Investigator
ポリコーム / PRC1.1 / Pcgf1 / エピジェネティクス / 骨髄異形成症候群 / ASC / MDS / インフラマソーム / 炎症性細胞死 / ストレス造血 … More / 細胞死 / emergency myelopoiesis / HOXA9 / emargency myelopoiesis / ポリコーム群抑制複合体 / GMP / Emergency myelopoiesis / PCGF1 / PRC1 / 腫瘍 / ポリコーム群遺伝子 / JAK2V617F / Cebpa / 造血幹・前駆細胞 / H2AK119ub1 / ポリコーム群複合体 / JAK2 / 骨髄球分化 / Pcgf5 / Pcgf4/Bmi1 / Pcgf3 / 造血幹細胞分化 / Non-canonical PRC1 / non-canonical PRC1 … More
Except Principal Investigator
プロテアソーム阻害剤 / EZH2阻害剤 / EZH2 / EZH2阻害薬 / ヒストンメチル化 / エピジェネティック異常 / 多発性骨髄腫 Less
  • Research Projects

    (5 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (7 People)
  •  Epigenetic regulation of inflammatory cell death and its etiologic significance in myelodysplastic syndromesPrincipal Investigator

    • Principal Investigator
      中島 やえ子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      The University of Tokyo
  •  Epigenetic Regulation Mechanisms in Stress HematopoiesisPrincipal Investigator

    • Principal Investigator
      Nakajima-Takagi Yaeko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      The University of Tokyo
  •  Role of the polycomb-group protein Pcgf1 in hematopoieticPrincipal Investigator

    • Principal Investigator
      Nakajima-Takagi Yaeko
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Chiba University
  •  The functional difference among Pcgf family proteins in hematopoietic systemPrincipal Investigator

    • Principal Investigator
      Nakajima-Takagi Yaeko
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Chiba University
  •  Abberant histone methylation as a therapeutic target in multiple myeloma

    • Principal Investigator
      MIMURA Naoya
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Chiba University

All 2023 2021 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis2023

    • Author(s)
      Nakajima-Takagi Yaeko、Oshima Motohiko、Takano Junichiro、Koide Shuhei、Itokawa Naoki、Uemura Shun、Yamashita Masayuki、Andoh Shohei、Aoyama Kazumasa、Isshiki Yusuke、Shinoda Daisuke、Saraya Atsunori、Arai Fumio、Yamaguchi Kiyoshi、Furukawa Yoichi、Koseki Haruhiko、Ikawa Tomokatsu、Iwama Atsushi
    • Journal Title

      eLife

      Volume: 12

    • DOI

      10.7554/elife.83004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07806, KAKENHI-PROJECT-23K07851, KAKENHI-PROJECT-21K08366, KAKENHI-PROJECT-22K16298, KAKENHI-PLANNED-19H05745, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653
  • [Journal Article] Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells2016

    • Author(s)
      Si S, Nakajima-Takagi Y, Aoyama K, Oshima M, Saraya A, Sugishita H, Nakayama M, Ishikura T, Koseki H, Iwama A
    • Journal Title

      PLoS One

      Volume: 11 Issue: 5 Pages: e0154561-e0154561

    • DOI

      10.1371/journal.pone.0154561

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-14J40042, KAKENHI-PROJECT-15K19544, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
  • [Journal Article] Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1.2015

    • Author(s)
      Fuse, Y., Nakajima, H., Nakajima-Takagi, Y., Nakajima, O. and Kobayashi, M.
    • Journal Title

      Genes Cells

      Volume: 20 Issue: 7 Pages: 590-600

    • DOI

      10.1111/gtc.12249

    • NAID

      120007135764

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26520101, KAKENHI-PROJECT-15K19544, KAKENHI-PUBLICLY-26116705, KAKENHI-PROJECT-14J40042
  • [Journal Article] Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.2015

    • Author(s)
      Wang C, Oshima M, Sashida G, Tomioka T, Hasegawa N, Mochizuki-Kashio M, Nakajima-Takagi Y, Kusunoki Y, Kyoizumi S, Imai K, Nakachi K, Iwama A.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 7 Pages: e0132041-e0132041

    • DOI

      10.1371/journal.pone.0132041

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461396, KAKENHI-PROJECT-15K19544, KAKENHI-PROJECT-14J40024, KAKENHI-PROJECT-14J40042
  • [Presentation] Polycomb repressive complex 1.1 negatively regulates inflammatory cell death2023

    • Author(s)
      Takanori Fukuta,Yaeko Nakajima,Kazumasa Aoyama,Shuhei Koide, Masayuki Yamashita,Motohiko Oshima,Atsushi Iwama
    • Organizer
      第85回日本血液学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07806
  • [Presentation] Polycomb repressive complex (PRC) 1.1 regulates emergency myelopoiesis and inflammatory cell death2021

    • Author(s)
      Yaeko Nakajima-Takagi, Shun Uemura1, Motohiko Oshima, Shuhei Koide, Shohei Andoh, Masayuki Yamashita, Atsushi Iwama.
    • Organizer
      第83回日本血液学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08728
  • [Presentation] Role of the polycomb-group protein Pcgf1 in the lineage commitment of hematopoietic stem and progenitor cells2017

    • Author(s)
      Yaeko Nakajima-Takagi, Yusuke Isshiki, Junichiro Takano, Motohiko Oshima, Sha Si, Kazumasa Aoyama, Atsunori Saraya, Haruhiko Koseki, Tomokatsu Ikawa and Atsushi Iwama
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16180
  • [Presentation] バリアント型ポリコーム抑制性複合体PRC1.1 は骨髄球分化決定を負に制御する2017

    • Author(s)
      中島 やえ子、岩間 厚志
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-17K16180
  • [Presentation] Role of the polycomb-group protein Pcgf1 in the lineage commitment of hematopoietic stem cells2016

    • Author(s)
      Yaeko Nakajima-Takagi, Motohiko Oshima, Sha Si, Atsunori Saraya, Tomokatsu Ikawa, Junichiro Takano, Haruhiko Koseki, and Atsushi Iwama
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県, 横浜市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K19544
  • [Presentation] Role of the polycomb group protein Pcgf1 in hematopoietic system.2015

    • Author(s)
      Yaeko Nakajima-Takagi, Motohiko Oshima, Sha Si, Atsunori Saraya, Haruhiko Koseki, Atsushi Iwama
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県立音楽堂(石川県, 金沢市)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K19544
  • [Presentation] Role of polycomb group protein Pcgf5 in hematopoietic system.2015

    • Author(s)
      Sha Si, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Atsunori Saraya, Haruhiko Koseki and Atsushi Iwama
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県立音楽堂(石川県, 金沢市)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K19544
  • [Presentation] Role of the polycomb gene Bcor in hematopoiesis2015

    • Author(s)
      Tomoyuki Tanaka, Yaeko Nakajima-Takagi, Motohiko Oshima, Atsunori Saraya, Shiro Tara, Sha Si, Hirohito Sone, Haruhiko Koseki, Atsushi Iwama
    • Organizer
      The 44th Annual Meeting of International Society for Experimental Hematology
    • Place of Presentation
      国立京都国際会館(京都府, 京都市)
    • Year and Date
      2015-09-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19544
  • 1.  IWAMA Atsushi (70244126)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  OHSHIMA Motohiko (70506287)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  MIMURA Naoya (00422220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  SHINODA daisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  小林 麻己人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  古関 明彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  指田 吾郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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