FUJIYOSHI MASACHIKA 藤吉正哉

… Alternative Names

藤吉正哉フジヨシマサチカ

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Researcher Number	50751921
Other IDs
Affiliation (Current)	2025: 鳥取大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 鳥取大学, 医学部附属病院, 准教授 2017 – 2020: 岡山大学, 医歯薬学総合研究科, 准教授 2018: 岡山大学大学院, 医歯薬学総合研究科(薬学系), 准教授 2016: 千葉大学, 大学院薬学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Medical pharmacy
Keywords	Principal Investigator 個別化医療 / LC-MS/MS / TDM / ラモトリギン / てんかん / 個別適正化 / 睡眠薬 / 定量分析 / LC/MS/MS / バイオマーカー … More / オーダーメイド医療 / レベチラセタム / 抗てんかん薬 / 薬物動態 … More Except Principal Investigator 薬学 / Direct Acting Antivirals / 遺伝子多型 / Direct Acting Antiviral / C型肝炎治療薬 / HCV / C型肝炎 / 薬物動態学 / 薬理遺伝学 / CYP3A4 / CYP3A5*3 / CYP3A5 Less

The development of TDM for hypnotic drugs using a micro blood samplingPrincipal Investigator
- Principal Investigator
  
  藤吉正哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tottori University
Prediction of lamotrigine clearance by using endogenous compounds as biomarkerPrincipal Investigator
- Principal Investigator
  
  Fujiyoshi Masachika
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Okayama University
Pharmacokinetics of new antiepileptic drugs and individualized therapy in pregnant womenPrincipal Investigator
- Principal Investigator
  
  FUJIYOSHI MASACHIKA
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University
  Chiba University
Pharmacogenetic study on anti-hepatitis C drugs based on CYP3A5 polymorphisms
- Principal Investigator
  
  Matsumoto Jun
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University
  International University of Health and Welfare

All 2024 2023 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] 薬剤師による院内処方継続理由への個別対応が医薬分業推進と薬物療法適正化に与える影響2024
- Author(s)
  小川勝弘、秦英司、太田友樹、栢木啓介、藤吉正哉、島田美樹
- Journal Title
  
  日本病院薬剤師会雑誌
  
  Volume: 60 Pages: 145-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06722
[Journal Article] Mechanism Underlying Conflicting Drug-Drug Interaction Between Aprepitant and Voriconazole via Cytochrome P450 3A4-Mediated Metabolism2024
- Author(s)
  Ishida Masako、Kumagai Takeshi、Yamamoto Tatsuro、Suzuki Hiroyuki、Moriki Kuniaki、Fujiyoshi Masachika、Nagata Kiyoshi、Shimada Miki
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 67 Issue: 1 Pages: 31-40
- DOI
  10.33160/yam.2024.02.004
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06722
[Journal Article] Development of a New Method for Simultaneous Quantitation of Plasma Concentrations of Voriconazole and Voriconazole <i>N</i>-Oxide Using Column-Switching LC-MS/MS and Its Application in Therapeutic Drug Monitoring2023
- Author(s)
  Yamamoto Tatsuro、Ishida Masako、Kodama Nao、Saiki Yusuke、Fujiyoshi Masachika、Shimada Miki
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 66 Issue: 3 Pages: 365-374
- DOI
  10.33160/yam.2023.08.009
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06722
[Journal Article] Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.2020
- Author(s)
  Izumi-Nakaseko H, Fujiyoshi M, Hagiwara-Nagasawa M, Goto A, Chiba K, Kambayashi R, Naito AT, Ando K, Kanda Y, Ishii I, Sugiyama A
- Journal Title
  
  Cardiovasc Toxicol.
  
  Volume: 20(1) Issue: 1 Pages: 58-70
- DOI
  10.1007/s12012-019-09538-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08608, KAKENHI-PROJECT-18K06748
[Journal Article] Population Pharmacokinetics of Vancomycin under Continuous Renal Replacement Therapy using a Polymethylmethacrylate Hemofilter2019
- Author(s)
  Yamazaki Shingo、Tatebe Mizuki、Fujiyoshi Masachika、Hattori Noriyuki、Suzuki Tatsuya、Takatsuka Hirokazu、Uchida Masashi、Suzuki Takaaki、Ishii Itsuko
- Journal Title
  
  Therapeutic Drug Monitoring
  
  Volume: - Issue: 3 Pages: 1-1
- DOI
  10.1097/ftd.0000000000000721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14946, KAKENHI-PROJECT-18K06748
[Journal Article] A proposed simple screening method to determine relative contributions of CYP3A4 and CYP3A5 to drug metabolism in vitro2019
- Author(s)
  Jun Matsumoto, Hiroyoshi Nakamura, Su Nwe San, Hikari Sato, Manami Takezawa, Ryuto Kishi, Yutaro Kito, Junko Sugano, Mai Izuki, Nao Yanagisawa, Naoki Ikeda, Yusuke Saito, Yoshinori Kato, Harumi Yamada, Masachika Fujiyoshi, and Noritaka Ariyoshi
- Journal Title
  
  Personalized Medicine Universe
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18955
[Journal Article] Minor contribution of CYP3A5 to the metabolism of hepatitis C protease inhibitor paritaprevir in vitro2018
- Author(s)
  Su Nwe San, Jun Matsumoto, Yumi Saito, Masako Koike, Hiroaki Sakaue, Yoshinori Kato, Masachika Fujiyoshi, Noritaka Ariyoshi, and Harumi Yamada
- Journal Title
  
  Xenobiotica
  
  Volume: 印刷中 Issue: 8 Pages: 935-944
- DOI
  10.1080/00498254.2018.1524947
- NAID
  120006768491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18955
[Presentation] CYP2C19内因性基質の代謝とボリコナゾール血中濃度の相関解析2023
- Author(s)
  藤吉正哉、山本達郎、島田美樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06722
[Presentation] 2種類の安定同位体標識化合物を用いたメラトニンの高感度定量とボリコナゾール血中濃度予測に向けた検討2023
- Author(s)
  藤吉正哉、山本達郎、島田美樹
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-22K06722
[Presentation] Toward clinical implementation of UGT1A4 activity-based approach for the prediction of lamotrigine clearance.2019
- Author(s)
  Masachika Fujiyoshi
- Organizer
  APSTJ Global Education Seminar 2019-1st
- Invited
- Data Source
  KAKENHI-PROJECT-18K06748
[Presentation] 妊娠・授乳期におけるラモトリギンのクリアランスおよび乳汁移行性の変動2019
- Author(s)
  岡田蛍子、藤吉正哉、土屋晃三、内田雅士、鈴木貴明、石井伊都子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K06748
[Presentation] Contribution of CYP3A5 to the metabolism of direct acting anti-hepatitis C virus drugs asunaprevir, daclatasvir, and beclabuvir (Ximency) in vitro2018
- Author(s)
  Jun Matsumoto, Su New San, Ayano Kawauchi, Shiho Yanaka, Natsumi Chiba, Ran Tagai, Ryoko Sanbe, Masachika Fujiyoshi, Harumi Yamada, and Noritaka Ariyoshi
- Organizer
  The 24th International Congress of Personalized Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18955
[Presentation] Minor contribution of cytochrome P450 3A5 to the metabolism of hepatitis C NS5B inhibitor beclabuvir in vitro2018
- Author(s)
  Su Nwe San, Jun Matsumoto, Yumi Saito, Masako Koike, Hiroaki Sakaue, Yoshinori Kato, Masachika Fujiyoshi, Noritaka Ariyoshi, and Harumi Yamada
- Organizer
  第28回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-16K18955
[Presentation] フェニトインの血中濃度が偽陰性を示す頻度の解析2018
- Author(s)
  藤吉正哉、鈴木貴明、石井伊都子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18931
[Presentation] Minor contribution of human cytochrome 3A5 to the metabolism of hepatitis C protease inhibitor paritaprevir in vitro2018
- Author(s)
  Su Nwe San, Jun Matsumoto, Yumi Saito, Masako Koike, Hiroaki Sakaue, Yoshinori Kato, Masachika Fujiyoshi, Noritaka Ariyoshi, and Harumi Yamada
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18955
[Presentation] ヒト血漿中ラモトリギンおよび主要代謝物の同時モニタリング2017
- Author(s)
  藤吉正哉、鈴木貴明、石井伊都子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K18931
[Presentation] ARCHITECTによるフェニトイン血中濃度測定で偽陰性を示す頻度の解析2017
- Author(s)
  藤吉正哉、鈴木貴明、石井伊都子
- Organizer
  第27回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-16K18931
[Presentation] ヒト血漿中のラモトリギンとその主要代謝物の同時測定法の確立2016
- Author(s)
  藤吉正哉、有吉範高、石井伊都子
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  京都
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K18931

1. Ariyoshi Noritaka (00243957)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. Matsumoto Jun (60709012)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. Yamada Harumi (70433620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. Nakamura Hiroyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 中瀬古寛子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 鈴木貴明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJIYOSHI MASACHIKA 藤吉 正哉

藤吉 正哉 フジヨシ マサチカ

Research Projects

Research Products

Co-Researchers

The development of TDM for hypnotic drugs using a micro blood samplingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prediction of lamotrigine clearance by using endogenous compounds as biomarkerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmacokinetics of new antiepileptic drugs and individualized therapy in pregnant womenPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pharmacogenetic study on anti-hepatitis C drugs based on CYP3A5 polymorphisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 薬剤師による院内処方継続理由への個別対応が医薬分業推進と薬物療法適正化に与える影響2024

Author(s)

Journal Title

Data Source

[Journal Article] Mechanism Underlying Conflicting Drug-Drug Interaction Between Aprepitant and Voriconazole via Cytochrome P450 3A4-Mediated Metabolism2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Development of a New Method for Simultaneous Quantitation of Plasma Concentrations of Voriconazole and Voriconazole <i>N</i>-Oxide Using Column-Switching LC-MS/MS and Its Application in Therapeutic Drug Monitoring2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Population Pharmacokinetics of Vancomycin under Continuous Renal Replacement Therapy using a Polymethylmethacrylate Hemofilter2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A proposed simple screening method to determine relative contributions of CYP3A4 and CYP3A5 to drug metabolism in vitro2019

Author(s)

Journal Title

Data Source

[Journal Article] Minor contribution of CYP3A5 to the metabolism of hepatitis C protease inhibitor paritaprevir in vitro2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] CYP2C19内因性基質の代謝とボリコナゾール血中濃度の相関解析2023

Author(s)

Organizer

Data Source

[Presentation] 2種類の安定同位体標識化合物を用いたメラトニンの高感度定量とボリコナゾール血中濃度予測に向けた検討2023

Author(s)

Organizer

Data Source

[Presentation] Toward clinical implementation of UGT1A4 activity-based approach for the prediction of lamotrigine clearance.2019

Author(s)

Organizer

Data Source

[Presentation] 妊娠・授乳期におけるラモトリギンのクリアランスおよび乳汁移行性の変動2019

FUJIYOSHI MASACHIKA 藤吉正哉

藤吉正哉フジヨシマサチカ