Yamamotoya Takeshi 山本屋武

Researcher Number	50760013
Other IDs
Affiliation (Current)	2024: 日本大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2024: 日本大学, 医学部, 助教 2019 – 2023: 広島大学, 医系科学研究科(医), 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(医), 助教 2015 – 2016: 広島大学, 医歯薬保健学研究院(医), 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Basic Section 53010:Gastroenterology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Metabolomics
Keywords	Principal Investigator 脂肪肝 / 細胞内小胞輸送 / 糖・脂質代謝 / 脂肪細胞 / 脂質代謝 / 糖尿病 / 翻訳後修飾 / 肥満 / Trk-fused gene （TFG) / 発現調節機構 … More / 神経筋接合部 / 神経変性疾患 / 脂質 / ミトコンドリア / PPARγ / TFG / インスリン分泌 … More Except Principal Investigator Pin1 / 代謝異常 / プロリン異性化酵素 / 脂質代謝 / メタボリックシンドローム / 代謝 / Hippoシグナル / 線維化 / 炎症 / 糖代謝異常 / 肝生検標本 / 脂肪蓄積 / NASH / コロナウイルス / ウイルス / COVID-19 / SARS-CoV-2 / 運動機能 / 筋肉 / 脂肪細胞 / 網膜症 / 糖・脂質代謝 / 腎症 / ＰＲＤＭ１６ / 基礎代謝 / Ｐｉｎ１ / 熱産生 / 糖代謝 / 肥満 / 糖尿病 Less

翻訳後修飾を介した脂質代謝調節機構およびTFGによるその制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  山本屋武
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nihon University
Hippo/YAP経路へのPin1作用と肝や脂肪組織の肥大、炎症、線維化への関与
- Principal Investigator
  
  浅野知一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
NASHの炎症、線維化におけるPin1の役割解明と臨床応用への展開
- Principal Investigator
  
  神名麻智
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hiroshima University
糖・脂質代謝における細胞内小胞輸送関連蛋白TFGの関与とその発現制御因子の解明Principal Investigator
- Principal Investigator
  
  山本屋武
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
Role of Pin1 in the proliferation of SARS-CoV-2
- Principal Investigator
  
  ASANO TOMOICHIRO
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Hiroshima University
Role of Pin1 in the muscle function and metabolic regulation
- Principal Investigator
  
  ASANO TOMOICHIRO
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
The functions of TFG in adipocytes, small intestine and hepatocytes and its involvement in metabolic disordersPrincipal Investigator
- Principal Investigator
  
  Yamamotoya Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
Significance of Trk-fused gene (TFG) in the pathogenesis of obesity and metabolic disordersPrincipal Investigator
- Principal Investigator
  
  Yamamotoya Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Roles of Pin1 and PAR 14 on the metabolic regulations
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Elucidation of the role of TFG in glucose and lipid metabolism in pancreas, liver and adipose tissuePrincipal Investigator
- Principal Investigator
  
  Yamamotoya Takeshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases2022
- Author(s)
  Yamamotoya Takeshi、Hasei Shun、Akasaka Yasuyuki、Ohata Yukino、Nakatsu Yusuke、Kanna Machi、Fujishiro Midori、Sakoda Hideyuki、Ono Hiraku、Kushiyama Akifumi、Misawa Hidemi、Asano Tomoichiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1966-1966
- DOI
  10.1038/s41598-022-05884-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K19380
[Journal Article] The expression of prolyl isomerase Pin1 is expanded in the skin of patients with atopic dermatitis and facilitates IL‐33 expression in HaCaT cells2022
- Author(s)
  Kanamoto Mayu、Takahagi Shunsuke、Aoyama Shunya、Kido Yuri、Nakanishi Mikako、Naito Miki、Kanna Machi、Yamamotoya Takeshi、Tanaka Akio、Hide Michihiro、Asano Tomoichiro、Nakatsu Yusuke
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 50 Issue: 4 Pages: 462-471
- DOI
  10.1111/1346-8138.16633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08346, KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-22K08077, KAKENHI-PROJECT-22K08655, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-21K19380
[Journal Article] Par14 interacts with the androgen receptor, augmenting both its transcriptional activity and prostate cancer proliferation2022
- Author(s)
  Naito M, Ikeda K, Aoyama S, Kanamoto M, Akasaka Y, Kido Y, Nakanishi M, Kanna M, Yamamotoya T, Matsubara A, Hinata N, Asano T, Nakatsu Y.
- Journal Title
  
  Cancer Med.
  
  Volume: - Issue: 7 Pages: 8464-8475
- DOI
  10.1002/cam4.5587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-22K08077, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-21K19380
[Journal Article] Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex2022
- Author(s)
  Aoyama S, Kido Y, Kanamoto M, Naito M, Nakanishi M, Kanna M, Yamamotoya T, Asano T, Nakatsu Y.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 425 Issue: 2 Pages: 113544-113544
- DOI
  10.1016/j.yexcr.2023.113544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-22K08655
[Journal Article] Roles of peptidyl prolyl isomerase Pin1 in viral propagation2022
- Author(s)
  Kanna M, Nakatsu Y, Yamamotoya T, Encinas J, Ito H, Okabe T, Asano T, Sakaguchi T.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 10 Pages: 1005325-1005325
- DOI
  10.3389/fcell.2022.1005325
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-22K08077, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-20K07515, KAKENHI-PROJECT-21K19380
[Journal Article] Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target2021
- Author(s)
  Yamamotoya T, Nakatsu Y, Kanna M, Hasei S, Ohata Y, Encinas J, Ito H, Okabe T, Asano T, Sakaguchi T.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 18581-18581
- DOI
  10.1038/s41598-021-97972-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-21K19380
[Journal Article] Prolyl isomerase Pin1 interacts with adipose triglyceride lipase and negatively controls both its expression and lipolysis2021
- Author(s)
  Yusuke Nakatsu, Takeshi Yamamotoya, Mizuki Okumura, Tetsuhiro Ishii, Mayu Kanamoto, Miki Naito, Mikako Nakanishi, Shunya Aoyama, Yasuka Matsunaga, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Hiraku Ono, Tomoichiro Asano
- Journal Title
  
  Metabolism
  
  Volume: 15 Pages: 154459-154459
- DOI
  10.1016/j.metabol.2020.154459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-18K08502
[Journal Article] Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells2021
- Author(s)
  Hasei S, Yamamotoya T, Nakatsu Y, Ohata Y, Itoga S, Nonaka Y, Matsunaga Y, Sakoda H, Fujishiro M, Kushiyama A, Asano T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 8 Pages: 4040-4040
- DOI
  10.3390/ijms22084040
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K08580
[Journal Article] Pathological Role of Pin1 in the Development of DSS-Induced Colitis2021
- Author(s)
  Matsunaga Yasuka、Hasei Shun、Yamamotoya Takeshi、Honda Hiroaki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Ito Hisanaka、Okabe Takayoshi、Asano Tomoichiro、Nakatsu Yusuke
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 5 Pages: 1230-1230
- DOI
  10.3390/cells10051230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580
[Journal Article] Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes2021
- Author(s)
  Fujishiro Midori、Ishihara Hisamitsu、Ogawa Katsuhiko、Murase Takayo、Nakamura Takashi、Watanabe Kentaro、Sakoda Hideyuki、Ono Hiraku、Yamamotoya Takeshi、Nakatsu Yusuke、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 8 Pages: 1052-1052
- DOI
  10.3390/biomedicines9081052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-20K08918, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580
[Journal Article] Prolyl isomerase Pin1 in metabolic reprogramming of cancer cells.2020
- Author(s)
  Nakatsu, Y., Yamamotoya, T., Ueda, K., Ono, H., Inoue, MK., Matsunaga, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Matsubara, A., and Asano, T.
- Journal Title
  
  Cancer Lett.
  
  Volume: 470 Pages: 106-114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Prolyl isomerase Pin1 in metabolic reprogramming of cancer cells2020
- Author(s)
  Nakatsu Yusuke、Yamamotoya Takeshi、Ueda Koji、Ono Hiraku、Inoue Masa-Ki、Matsunaga Yasuka、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Matsubara Akio、Asano Tomoichiro
- Journal Title
  
  Cancer Letters
  
  Volume: 470 Pages: 106-114
- DOI
  10.1016/j.canlet.2019.10.043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-20H03732
[Journal Article] Possible Involvement of Normalized Pin1 Expression Level and AMPK Activation in the Molecular Mechanisms Underlying Renal Protective Effects of SGLT2 Inhibitors in Mice.2019
- Author(s)
  Inoue, MK., Matsunaga, Y., Nakatsu, Y., Yamamotoya, T., Ueda, K., Kushiyama, A., Sakoda, H., Fujishiro, M., Ono, H., Iwashita, M., Sano, T., Nishimura, F., Morii, K., Sasaki, K., Masaki, T., and Asano, T
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 11 Pages: 57-57
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins2019
- Author(s)
  Inoue Masa-Ki、Nakatsu Yusuke、Yamamotoya Takeshi、Hasei Shun、Kanamoto Mayu、Naitou Miki、Matsunaga Yasuka、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Kushiyama Akifumi、Asano Tomoichiro
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 12 Pages: 1545-1545
- DOI
  10.3390/cells8121545
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K16150
[Journal Article] Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation.2019
- Author(s)
  Ueda K, Nakatsu Y, Yamamotoya T, Ono H, Inoue Y, Inoue MK, Mizuno Y, Matsunaga Y, Kushiyama A, Sakoda H, Fujishiro M, Takahashi SI, Matsubara A, Asano T.
- Journal Title
  
  Oncotarget
  
  Volume: 10 Pages: 1637-1648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice2019
- Author(s)
  Inoue Masa-Ki、Matsunaga Yasuka、Nakatsu Yusuke、Yamamotoya Takeshi、Ueda Koji、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Iwashita Misaki、Sano Tomomi、Nishimura Fusanori、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Asano Tomoichiro
- Journal Title
  
  Diabetology & Metabolic Syndrome
  
  Volume: 11 Issue: 1 Pages: 57-57
- DOI
  10.1186/s13098-019-0454-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150
[Journal Article] Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins2019
- Author(s)
  Inoue, MK., Nakatsu, Y., Yamamotoya, T., Hasei, S., Kanamoto, M., Naitou, M., Matsunaga, Y., Sakoda, H., Fujishiro, M., Ono, H., Kushiyama, A., and Asano, T.
- Journal Title
  
  Cells
  
  Volume: 8 Pages: 1545-1545
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Prolyl Isomerase Pin1 Binds to and Stabilizes Acetyl CoA Carboxylase 1 Protein, Thereby Supporting Cancer Cell Proliferation2019
- Author(s)
  Ueda, K., Nakatsu, Y., Yamamotoya, T., Ono, H., Inoue, Y., Inoue, MK., Mizuno, Y., Matsunaga, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Takahashi, SI., Matsubara, A., and Asano, T.
- Journal Title
  
  Oncotarget
  
  Volume: 10 Pages: 1637-1648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects Against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.2019
- Author(s)
  Mizuno, Y., Yamamotoya, T., Nakatsu, Y., Ueda, K., Matsunaga, Y., Inoue, MK., Sakoda, H., Fujishiro, M., Ono, H., Kikuchi, T., Takahashi, M., Morii, K., Sasaki, K., Masaki, T., Asano, T., and Kushiyama, A.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 20 Pages: 4680-4680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu, Y., Matsunaga, Y., Yamamotoya, T., Sano, T., Yamawaki, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Ryo, A., Ono, H., Minamino, T., Takahashi, SI., Ohno, H., Yoneda, M., Takahashi, K., Ishihara, H., Katagiri, H., Nishimura, F., Kanematsu, T., Yamada, T.,and Asano, T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Pages: 3221-3230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice2019
- Author(s)
  Mizuno Yu、Yamamotoya Takeshi、Nakatsu Yusuke、Ueda Koji、Matsunaga Yasuka、Inoue Masa-Ki、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Kikuchi Takako、Takahashi Masahiro、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 19 Pages: 4680-4680
- DOI
  10.3390/ijms20194680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-17K16150
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep
  
  Volume: 26 Pages: 3221-3230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation2019
- Author(s)
  Ueda Koji、Nakatsu Yusuke、Yamamotoya Takeshi、Ono Hiraku、Inoue Yuki、Inoue Masa-Ki、Mizuno Yu、Matsunaga Yasuka、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Takahashi Shin-Ichiro、Matsubara Akio、Asano Tomoichiro
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 17 Pages: 1637-1648
- DOI
  10.18632/oncotarget.26691
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-25221204
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Development of Pin1 inhibitors and their potential as therapeutic agents.2018
- Author(s)
  Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T.
- Journal Title
  
  Curr Med Chem.
  
  Volume: 10 Pages: 2174-2174
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications2018
- Author(s)
  Okubo Hirofumi、Kushiyama Akifumi、Nakatsu Yusuke、Yamamotoya Takeshi、Matsunaga Yasuka、Fujishiro Midori、Sakoda Hideyuki、Ohno Haruya、Yoneda Masayasu、Asano Tomoichiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 10 Pages: 3064-3064
- DOI
  10.3390/ijms19103064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model2018
- Author(s)
  Inoue Masa-Ki、Yamamotoya Takeshi、Nakatsu Yusuke、Ueda Koji、Inoue Yuki、Matsunaga Yasuka、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Suzuki Yusuke、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 12 Pages: 3967-3967
- DOI
  10.3390/ijms19123967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages2018
- Author(s)
  Yamazaki Hiroki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Yamamotoya Takeshi、Nakatsu Yusuke、Kikuchi Takako、Kaneko Sunao、Tanaka Hirotoshi、Asano Tomoichiro
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2018 Pages: 1-12
- DOI
  10.1155/2018/3062319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-17K16158, KAKENHI-PROJECT-16H05330, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] Development of Pin1 inhibitors and their potential as therapeutic agents.2018
- Author(s)
  Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T.
- Journal Title
  
  Curr Med Chem
  
  Volume: - Issue: 20 Pages: 1-1
- DOI
  10.2174/0929867325666181105120911
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09791
[Journal Article] The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.2018
- Author(s)
  Inoue MK, Yamamotoya T, Nakatsu Y, Ueda K, Inoue Y, Matsunaga Y, Sakoda H, Fujishiro M, Ono H, Morii K, Sasaki K, Masaki T, Suzuki Y, Asano T, Kushiyama A.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Development of Pin1 inhibitors and their potential as therapeutic agents.2018
- Author(s)
  Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T.
- Journal Title
  
  Curr Med Chem
  
  Volume: 10 Pages: 2174-2174
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Gut microbiota as a　therapeutic target for metabolic disorders.2018
- Author(s)
  Okubo H, Nakatsu Y, Kushiyama A, Yamamotoya T, Matsunaga Y, Inoue MK,　Fujishiro M, Sakoda H, Ohno H, Yoneda M, Ono H, Asano T.
- Journal Title
  
  Curr Med Chem.
  
  Volume: 25 Issue: 9 Pages: 984-1001
- DOI
  10.2174/0929867324666171009121702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-16K19538, KAKENHI-PROJECT-18K08502
[Journal Article] The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.2018
- Author(s)
  Inoue MK, Yamamotoya T, Nakatsu Y, Ueda K, Inoue Y, Matsunaga Y, Sakoda H, Fujishiro M, Ono H, Morii K, Sasaki K, Masaki T, Suzuki Y, Asano T, Kushiyama A.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04200
[Journal Article] Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-13432-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.2017
- Author(s)
  Yusuke Nakatsu, Hiroki Kokubo, Batmunkh Bumdelger, Masao Yoshizumi, Takeshi Yamamotoya, Yasuka Matsunaga, Koji Ueda, Yuki Inoue, Masa-Ki Inoue, Midori Fujishiro, Akifumi Kushiyama, Hiraku Ono, Hideyuki Sakoda, and Tomoichiro Asano
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18(8) Issue: 8 Pages: 1704-1717
- DOI
  10.3390/ijms18081704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08443, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion2017
- Author(s)
  Nakatsu Y, Mori K, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mitsuzaki-Miyoshi K, Sakoda H, Fujishiro M, Yamaguchi S, Kushiyama A, Ono H, Ishihara H, Asano T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 28 Pages: 11886-11895
- DOI
  10.1074/jbc.m117.780726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] Gastrointestinal symptom prevalence depends on disease duration and gastrointestinal region in type 2 diabetes mellitus2017
- Author(s)
  Fujishiro M, Kushiyama A, Yamazaki H, Kaneko S, Koketsu Y, Yamamotoya T, Kikuchi T, Sakoda H, Suzuki R, Kadowaki T
- Journal Title
  
  World J Gastroenterol
  
  Volume: 23 Issue: 36 Pages: 6694-6704
- DOI
  10.3748/wjg.v23.i36.6694
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09776, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K16150
[Journal Article] Reduced SHARPIN and LUBAC formation may contribute to CCl4- or acetaminophen-induced liver cirrhosis in mice.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Matsunaga Y, Fukushima T, Yamazaki H, Kaneko S, Fujishiro M, Kikuchi T, Kushiyama A, Tokunaga F, Asano T, and Sakoda H.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 18 Issue: 2 Pages: 326-326
- DOI
  10.3390/ijms18020326
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-15H06427, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-16K09784
[Journal Article] Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.2016
- Author(s)
  Kushiyama A, Nakatsu Y, Matsunaga Y, Yamamotoya T, Mori K, Ueda K, Inoue Y, Sakoda H, Fujishiro M, Ono H, Asano T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2016 Pages: 8603164-8603164
- DOI
  10.1155/2016/8603164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06427, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-16K09791
[Journal Article] Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.2016
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mori K, Sakoda H, Fujishiro M, Ono H, Kushiyama A, Asano T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 17 (9) Issue: 9 Pages: 1495-1495
- DOI
  10.3390/ijms17091495
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06427, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791
[Presentation] Trk-fused gene (TFG) の脂肪細胞分化および成熟脂肪細胞における役割の検討2023
- Author(s)
  山本屋武, 大畠侑乃, 赤坂保行, 迫田秀之, 藤城緑, 櫛山暁史, 浅野知一郎
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08580
[Presentation] 骨格筋TFGの肥満形成および神経筋接合部の維持における役割2022
- Author(s)
  山本屋武, 大畠侑乃, 赤坂保行, 神名麻智, 中津祐介, 迫田秀之, 藤城緑, 櫛山暁史, 浅野知一郎
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08580
[Presentation] 骨格筋TFGの肥満形成および神経筋接合部の維持における役割2022
- Author(s)
  山本屋武, 大畠侑乃, 赤坂保行, 神名麻智, 中津祐介, 迫田秀之, 藤城緑, 櫛山暁史, 浅野知一郎
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] ロリン異性化酵素Pin1は，骨格筋のSERCA1/2機能を制御し，全身の代謝調節に関与する2021
- Author(s)
  中津　祐介、山本屋　武、長谷井　竣、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] Trk-fused gene（TFG）の骨格筋機能および肥満発症における役割2021
- Author(s)
  長谷井　竣、山本屋　武、中津　祐介、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] 脂肪細胞のTrk-fused gene（TFG）はPPARγ発現量およびミトコンドリア機能を調節し，adipose expansionに重要である2021
- Author(s)
  山本屋　武、長谷井　竣、中津　祐介、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] Trk-fused gene (TFG) の脂肪細胞における代謝制御機構の解明2021
- Author(s)
  山本屋武, 長谷井竣, 中津祐介, 大畠侑乃, 迫田秀之, 藤城緑, 櫛山暁史, 浅野知一郎
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08580
[Presentation] 2型糖尿病を対象としたプリン体代謝関連物質の血管合併症発症および進展に対する影響の研究（続報）2021
- Author(s)
  藤城　緑、櫛山　暁史、小川　克彦、渡邉　健太郎、江頭　富士子、岡本　真由美、村瀬　貴代、中村　敬志、赤利　精梧、迫田　秀之、小野　啓、山本屋　武、中津　祐介、浅野　知一郎、石原　寿光
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] Trk-fused gene (TFG) の脂肪細胞における代謝制御機構の解明2021
- Author(s)
  山本屋武, 長谷井竣, 中津祐介, 大畠侑乃, 迫田秀之, 藤城緑, 櫛山暁史, 浅野知一郎
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] プロリン異性化酵素Pin1は，骨格筋のSERCA1/2機能を制御し，全身の代謝調節に関与する2020
- Author(s)
  中津　祐介、山本屋　武、長谷井　竣、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] 脂肪細胞のTrk-fused gene (TFG) はPPARγ発現量およびミトコンドリア機能を調節し, adipose expansionに重要である2020
- Author(s)
  山本屋武、長谷井竣、中津祐介、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] 脂肪細胞のTrk-fused gene（TFG）はPPARγ発現量およびミトコンドリア機能を調節し，adipose expansionに重要である2020
- Author(s)
  山本屋　武、長谷井　竣、中津　祐介、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] Trk-fused gene（TFG）の骨格筋機能および肥満発症における役割2020
- Author(s)
  長谷井　竣、山本屋　武、中津　祐介、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] 2型糖尿病を対象としたプリン体代謝関連物質の血管合併症発症および進展に対する影響の研究（続報）2020
- Author(s)
  藤城　緑、櫛山　暁史、小川　克彦、渡邉　健太郎、江頭　富士子、岡本　真由美、村瀬　貴代、中村　敬志、赤利　精梧、迫田　秀之、小野　啓、山本屋　武、中津　祐介、浅野　知一郎、石原　寿光
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03732
[Presentation] Trk-fused gene (TFG) の骨格筋機能および肥満発症における役割2020
- Author(s)
  長谷井竣, 山本屋武, 中津祐介, 迫田秀之, 藤城緑, 櫛山暁史, 浅野知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] SGLT2阻害薬によるマウス糖尿病性腎障害の改善及び、腎Pin1発現量の是正とAMPK活性化の関与2019
- Author(s)
  井上　賢紀、中津　祐介、松永　泰花、山本屋　武、上田　晃司、井上　由貴、水野　優、櫛山　暁史、浅野　知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] 脂肪細胞のTrk-fused gene (TFG) による代謝制御機構の解明2019
- Author(s)
  山本屋武、長谷井竣、中津祐介、井上賢紀、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K16150
[Presentation] 脂肪細胞のTrk-fused gene (TFG) による代謝制御機構の解明2019
- Author(s)
  山本屋武、長谷井竣、中津祐介、井上賢紀、櫛山暁史、浅野知一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] 骨格筋Pin1は、運動機能及び糖代謝を制御する2019
- Author(s)
  中津　祐介、中井　菜摘、伊藤　輝、山本屋　武、上田　晃司、井上　賢紀、水野　優、味八木　茂、安達　伸生、櫛山　暁史、浅野　知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] キサンチンオキシターゼ阻害薬febuxostatによる糖尿病性腎症の改善とその作用機序の解明2019
- Author(s)
  水野　優、中津　祐介、山本屋　武、上田　晃司、井上　賢紀、藤城　緑、迫田　秀之、櫛山　暁史、浅野　知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] 脂肪細胞のTrk-fused gene (TFG) による代謝制御機構の解明2019
- Author(s)
  山本屋武、長谷井竣、中津祐介、井上賢紀、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] Pin1 and Trk-fused gene (TFG): novel regulators for β-cell mass and function2019
- Author(s)
  Takeshi Yamamotoya, Yusuke Nakatsu, Akifumi Kushiyama, Hisamitsu Ishihara, Tomoichiro Asano
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17986
[Presentation] 脂肪細胞のTrk-fused gene (TFG) による代謝制御機構の解明2019
- Author(s)
  山本屋武、長谷井竣、中津祐介、井上賢紀、櫛山暁史、浅野知一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K16150
[Presentation] Trk-fused gene (TFG) の糖代謝調節における役割の解明2019
- Author(s)
  山本屋武，中津祐介，上田晃嗣，井上賢紀，迫田秀之，藤城緑，櫛山暁史，石原寿光，浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K16150
[Presentation] 脂肪細胞のTrk-fused gene (TFG) による代謝制御機構の解明2019
- Author(s)
  山本屋武、中津祐介、上田晃嗣、井上賢紀、櫛山暁史、浅野知一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K16150
[Presentation] 脂肪細胞のTrk-fused gene (TFG)による代謝制御機構の解明2019
- Author(s)
  山本屋　武、長谷井　俊、中津　祐介、井上　賢紀、迫田　秀之、藤城　緑、櫛山　暁史、浅野　知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] Pin1 and Trk-fused gene (TFG): novel regulators for β-cell mass and function2019
- Author(s)
  Takeshi Yamamotoya, Yusuke Nakatsu, Akifumi Kushiyama, Hisamitsu Ishihara, Tomoichiro Asano.
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16150
[Presentation] Pin1 and Trk-fused gene (TFG): novel regulators for beta-cell mass and function2019
- Author(s)
  山本屋　武、中津　祐介、櫛山　暁史、石原　寿光、浅野　知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] SGLT2阻害薬によるマウス糖尿病性腎症の改善及び、腎Pin1発現量の是正とAMPK活性化の関与2018
- Author(s)
  井上賢紀、中津祐介、松永泰花、山本屋武、上田晃嗣、井上由貴、櫛山暁史、浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] Trk-fused gene (TFG) の糖代謝調節における役割の解明2018
- Author(s)
  山本屋武，中津祐介，上田晃嗣，井上賢紀，迫田秀之，藤城緑，櫛山暁史，石原寿光，浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] プロリン異性化酵素Pin1による脂肪蓄積制御機構の解明2018
- Author(s)
  中津祐介，山本屋武，上田晃嗣，井上賢紀，井上由貴，櫛山暁史，浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] 2型糖尿病を対象としたキサンチン酸化還元酵素の血管合併症発症および進展に対する影響に関する探索研究2018
- Author(s)
  藤城緑，櫛山暁史，山口賢，渡邉健太郎，江頭富士子，岡本真由美，村瀬貴代，中村敬志，山本屋武，中津祐介，浅野知一郎，石原寿光
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2018
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山本屋武、山崎広貴、中津祐介、浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2018
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山本屋武、山崎広貴、中津祐介、浅野地一郎、河津捷二
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] 2型糖尿病を対象としたキサンチン酸化還元酵素の血管合併症発症および進展に対する影響に関する探索研究2018
- Author(s)
  藤城緑、櫛山暁史、山口賢、渡辺健太郎、江頭富士子、岡本真由美、村瀬貴代、中村敬志、山本屋武、中津祐介、浅野知一郎、石原寿光
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] Trk-fused gene (TFG)の糖代謝調節における役割の解明2018
- Author(s)
  山本屋武、中津祐介、上田晃嗣、井上賢紀、迫田秀之、藤城緑、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] プロリン異性化酵素Pin1による脂肪蓄積制御機構の解明2018
- Author(s)
  中津祐介、山本屋武、上田晃嗣、井上賢紀、井上由貴、櫛山暁史、浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] SGLT2阻害薬によるマウス糖尿病性腎障害の改善及び、腎Pin1発現量の是正とAMPK活性化の関与2018
- Author(s)
  井上賢紀，中津祐介，松永泰花，山本屋武，上田晃嗣，井上由貴，櫛山暁史，浅野知一郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04200
[Presentation] Trk-fused gene (TFG) の膵β細胞における役割の解明2017
- Author(s)
  山本屋武，中津祐介，松永泰花，井上由貴，迫田秀之，藤城緑，山崎広貴，菊池貴子，櫛山暁史，浅野知一郎
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K16150
[Presentation] Trk-fused gene (TFG) の膵β細胞における役割の解明2016
- Author(s)
  山本屋武、中津祐介、迫田秀之、藤城緑、山崎広貴、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15H06427
[Presentation] 膵β細胞におけるTrk-fused gene (TFG) の役割2016
- Author(s)
  山本屋武、中津祐介、松永泰花、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H06427

1. Asano Tomoichiro (70242063)

# of Collaborated Projects: 5 results

# of Collaborated Products: 36 results
2. 中津祐介 (20452584)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
3. 神名麻智 (10619365)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 相方浩 (30403512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小野啓 (10570616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 迫田秀之 (50376464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. KUSHIYAMA Akifumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
8. YOSHIZUMI Masao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SUZUKI Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. Kadowaki Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 小久保博樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 秀道広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 徳永文稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamotoya Takeshi 山本屋 武

Research Projects

Research Products

Co-Researchers

翻訳後修飾を介した脂質代謝調節機構およびTFGによるその制御メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

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Hippo/YAP経路へのPin1作用と肝や脂肪組織の肥大、炎症、線維化への関与

Principal Investigator

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NASHの炎症、線維化におけるPin1の役割解明と臨床応用への展開

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Research Institution

糖・脂質代謝における細胞内小胞輸送関連蛋白TFGの関与とその発現制御因子の解明Principal Investigator

Principal Investigator

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Role of Pin1 in the proliferation of SARS-CoV-2

Principal Investigator

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Role of Pin1 in the muscle function and metabolic regulation

Principal Investigator

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The functions of TFG in adipocytes, small intestine and hepatocytes and its involvement in metabolic disordersPrincipal Investigator

Principal Investigator

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Significance of Trk-fused gene (TFG) in the pathogenesis of obesity and metabolic disordersPrincipal Investigator

Principal Investigator

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Roles of Pin1 and PAR 14 on the metabolic regulations

Principal Investigator

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Elucidation of the role of TFG in glucose and lipid metabolism in pancreas, liver and adipose tissuePrincipal Investigator

Principal Investigator

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[Journal Article] Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases2022

Author(s)

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Data Source

[Journal Article] The expression of prolyl isomerase Pin1 is expanded in the skin of patients with atopic dermatitis and facilitates IL‐33 expression in HaCaT cells2022

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DOI

Data Source

[Journal Article] Par14 interacts with the androgen receptor, augmenting both its transcriptional activity and prostate cancer proliferation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex2022

Yamamotoya Takeshi 山本屋武