sako keisuke 迫圭輔

… Alternative Names

SAKO KEISUKE 迫圭輔

迫圭輔サコケイスケ

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Researcher Number	50786291
Other IDs	https://orcid.org/0000-0002-6453-8075
Affiliation (Current)	2026: 国立研究開発法人国立循環器病研究センター, 研究所, 室長 2026: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2024 – 2025: 慶應義塾大学, 医学部(信濃町), 講師 2019 – 2024: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2009: Osaka University, 医学系研究科, 特別研究員(PD) 2008: Osaka University, 医学系研究科, 特別研究員(DC2)
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Living organism molecular science Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Transformative Research Areas, Section (III) / Basic Section 44040:Morphology and anatomical structure-related / Medium-sized Section 48:Biomedical structure and function and related fields
Keywords	Principal Investigator 細胞外pH / 細胞膜 / 脂質 / 初期発生 / ゼブラフィッシュ / PIP2 / pH / 肺呼吸 / 平面内細胞極性 / Wnt … More / PTK7 / 平面内細胞極 / イノシトールリン脂質 / フォスファチジルイノシトール … More Except Principal Investigator 発生 / 恒常性維持 / 適度な運動 / 間質液 / 生体恒常性維持 / 運動模倣介入 / メカニカルストレス / がん / シグナル伝達 / プロトン / 上皮細胞 / ガス交換組織 / 生体イメージング / 血管内皮細胞 / 器官形成 / 側板中胚葉 / イメージング / 左右非対称 / 情報伝達系 / 中胚葉 / 左右軸 / 内胚葉 / クッパー胞 / 左右左 / ゼブラフィッシュ / カルシウム / 繊毛 / クッパ―胞 / 左右非対称性 Less

pH signal via extracellular proton field formation
- Principal Investigator
  
  船戸洋佑
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Analses of the formation of oxygen exchange niche through endothelial-epithelial interaction
- Principal Investigator
  
  中嶋洋行
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  National Cardiovascular Center Research Institute
力学の理解に基づく代謝異常症及び認知機能障害に対する革新的治療法開発の基盤構築
- Principal Investigator
  
  澤田泰宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Analysis of the molecular mechanisms and physiological significance of the extracellular pH responsePrincipal Investigator
- Principal Investigator
  
  迫圭輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Keio University
Mechanisms of pH-dependent cellular responses mediated by membrane phospholipidsPrincipal Investigator
- Principal Investigator
  
  SAKO KEISUKE
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  National Cardiovascular Center Research Institute
Clarifying left-right asymmetry by imaging of cell signaling and tissue development
- Principal Investigator
  
  Mochizuki Naoki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  National Cardiovascular Center Research Institute
PTK7による平面内細胞極性形成機構とその形態形成における役割の解析Principal Investigator
- Principal Investigator
  
  迫圭輔
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University

All 2025 2023 2022 2021 2008

All Journal Article Presentation

[Journal Article] Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish2023
- Author(s)
  Hiroyuki Nakajima, Hiroyuki Ishikawa, Takuya Yamamoto, Ayano Chiba, Hajime Fukui, Keisuke Sako, Moe Fukumoto, Kenny Mattonet, Hyouk-Bum Kwon, Subhra P Hui, Gergana D Dobreva, Kazu Kikuchi, Christian S M Helker, Didier Y R Stainier, Naoki Mochizuki
- Journal Title
  
  Developmental Cell
  
  Volume: 58 Issue: 3 Pages: 224-238
- DOI
  10.1016/j.devcel.2022.12.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06764, KAKENHI-PROJECT-22K15156, KAKENHI-PROJECT-20H03683, KAKENHI-PROJECT-20K20532, KAKENHI-PROJECT-19H01022
[Journal Article] Mechanical load regulates bone growth via periosteal Osteocrin2021
- Author(s)
  Watanabe-Takano H., Ochi H., Chiba A., Matsuo A., Kanai Y., Fukuhara S., Ito N., Sako K., Miyazaki T., Tainaka K., Harada I., Sato S., Sawada Y., Minamino N., Takeda S., Ueda H.R., Yasoda A., Mochizuki N.
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 2 Pages: 109380-109380
- DOI
  10.1016/j.celrep.2021.109380
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22517, KAKENHI-PROJECT-20K21246, KAKENHI-PROJECT-20K21778, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-19H01022, KAKENHI-PROJECT-21H04866, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-19H03777, KAKENHI-PROJECT-21H02665, KAKENHI-PROJECT-20K08877, KAKENHI-PROJECT-21K19358, KAKENHI-PROJECT-21K19556, KAKENHI-PROJECT-20K08414
[Presentation] TM9SF3-mediated adaptation to extracellular acidic pH through PI(4,5)P2 flop2025
- Author(s)
  迫　圭輔
- Organizer
  APPW2025 第130回日本解剖学会・第102回日本生理学会・第98回日本薬理学会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-24K09294
[Presentation] pH-dependent PIP2 translocation system is essential for zebrafish development2022
- Author(s)
  迫　圭輔
- Organizer
  28回　小型魚類研究会
- Data Source
  KAKENHI-PROJECT-21K05983
[Presentation] Angiopoietin-1は、Phosphoinositide 3-Kinase/AKT/Myocyte Enhancer Factor 2経路を介して Kruppel-Like Factor 2の発現を誘導する2008
- Author(s)
  Keisuke Sako
- Organizer
  日本分子細胞生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-08J05257

1. 中嶋洋行 (10467657)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Mochizuki Naoki (30311426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 福井一 (80551506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 長谷川洋介 (30396783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山本拓也 (60546993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 伊東潤二 (10638844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 船戸洋佑 (60505775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 澤田泰宏 (50313135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 崎谷直義 (30824859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 住谷瑛理子 (50724754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 篠原正浩 (60345733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 青木吉嗣 (80534172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鮎川保則 (50304697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 川内敬子 (40434138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 福原茂朋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sako keisuke 迫 圭輔

SAKO KEISUKE 迫 圭輔

迫 圭輔 サコ ケイスケ

Research Projects

Research Products

Co-Researchers

pH signal via extracellular proton field formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analses of the formation of oxygen exchange niche through endothelial-epithelial interaction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

力学の理解に基づく代謝異常症及び認知機能障害に対する革新的治療法開発の基盤構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the molecular mechanisms and physiological significance of the extracellular pH responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of pH-dependent cellular responses mediated by membrane phospholipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarifying left-right asymmetry by imaging of cell signaling and tissue development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PTK7による平面内細胞極性形成機構とその形態形成における役割の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanical load regulates bone growth via periosteal Osteocrin2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] TM9SF3-mediated adaptation to extracellular acidic pH through PI(4,5)P2 flop2025

Author(s)

Organizer

Data Source

[Presentation] pH-dependent PIP2 translocation system is essential for zebrafish development2022

Author(s)

Organizer

Data Source

[Presentation] Angiopoietin-1は、Phosphoinositide 3-Kinase/AKT/Myocyte Enhancer Factor 2経路を介して Kruppel-Like Factor 2の発現を誘導する2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

sako keisuke 迫圭輔

SAKO KEISUKE 迫圭輔

迫圭輔サコケイスケ