Sakitani Naoyoshi 崎谷直義

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Sakitani Naoyosi 崎谷直義

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Researcher Number	30824859
Other IDs
Affiliation (Current)	2026: 国立研究開発法人産業技術総合研究所, セルフケア実装研究センター, 研究員 2026: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員
Affiliation (based on the past Project Information) *help	2023 – 2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員 2022: 国立研究開発法人国立循環器病研究センター, 研究所, リサーチフェロー 2020 – 2021: 国立障害者リハビリテーションセンター(研究所), 研究所運動機能系障害研究部, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 59010:Rehabilitation science-related Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 59010:Rehabilitation science-related / Basic Section 59020:Sports sciences-related
Keywords	Principal Investigator 運動 / メカニカルストレス / 力学的刺激 / 脂肪性肝疾患 / 糖尿病 / 糖代謝機能 / 物理的刺激 / 運動療法 / 変形性膝関節症 Except Principal Investigator メカニカルストレス … More / 生体恒常性維持 / 恒常性維持 / 適度な運動 / 間質液 / 動物実験 / 急性期 / 理学療法 / 物理療法 / イソフラボン / 熱刺激 / 筋機能低下 / 骨格筋 / ステロイド / 再生リハビリテーション / 関節軟骨 / 脳損傷 / 細胞置換治療 / 細胞リハビリテーション / 骨粗鬆症 / 筋萎縮 / 腱 / 臓器連関 / 運動模倣介入 / 抗炎症 / 身体不活動 / 慢性炎症 / 本態性高血圧 / メカノバイオロジー / 流体剪断力 / 高血圧 Less

運動模倣力学的刺激による脂肪性肝疾患改善の分子機序解明に基づく、運動の本質の理解Principal Investigator
- Principal Investigator
  
  崎谷直義
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
筋萎縮と骨粗鬆症を同時に防ぐ腱を標的とした新たなアプローチ
- Principal Investigator
  
  土屋吉史
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
力学の理解に基づく代謝異常症及び認知機能障害に対する革新的治療法開発の基盤構築
- Principal Investigator
  
  澤田泰宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Research on Cellular Rehabilitation to Facilitate Cell Replacement Therapy
- Principal Investigator
  
  伊藤明良
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto University
Establishment of Novel Treatment Strategies for Skeletal Muscle Dysfunction in Patients Undergoing Steroid Therapy
- Principal Investigator
  
  土田和可子
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
物理療法による超急性期リハビリテーションの創出
- Principal Investigator
  
  伊藤明良
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kyoto University
脳内メカニカルストレスに着目した、運動による糖尿病改善効果の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  崎谷直義
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Uncovering the pathogenesis of essential hypertension via mechanobiological approach
- Principal Investigator
  
  Sawada Yasuhiro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Molecular mechanisms of how mechanical stresses alleviate chronic inflammation of the brain and muscles induced by physical inactivity
- Principal Investigator
  
  Sawada Yasuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Deciphering the molecular mechanisms of osteoarthritis by recapitulating the positive effects of exercise on osteoarthritis with mechanical interventionPrincipal Investigator
- Principal Investigator
  
  Sakitani Naoyosi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Cardiovascular Center Research Institute
  National Rehabilitation Center for Persons with Disabilities

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Biological characterization of breast cancer spheroid formed by fast fabrication method2024
- Author(s)
  Iijima Yuta、Uenaka Norino、Morimoto Mayu、Sato Daiki、Hirose Satomi、Sakitani Naoyoshi、Shinohara Masahiro、Funamoto Kenichi、Hayase Gen、Yoshino Daisuke
- Journal Title
  
  In vitro models
  
  Volume: 3 Issue: 1 Pages: 19-32
- DOI
  10.1007/s44164-024-00066-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16632, KAKENHI-PROJECT-21K19893
[Journal Article] Histological changes in skeletal muscle induced by heart failure in human patients and animal models: A scoping review2024
- Author(s)
  Kaneguchi Akinori、Sakitani Naoyoshi、Umehara Takuya
- Journal Title
  
  Acta Histochemica
  
  Volume: 126 Issue: 8 Pages: 152210-152210
- DOI
  10.1016/j.acthis.2024.152210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16632
[Journal Article] Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans2023
- Author(s)
  Murase Shuhei、Sakitani Naoyoshi、Maekawa Takahiro、Yoshino Daisuke、Takano Kouji、Konno Ayumu、Hirai Hirokazu、Saito Taku、et al
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 7 Issue: 11 Pages: 1350-1373
- DOI
  10.1038/s41551-023-01061-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-23K16632, KAKENHI-PROJECT-22K06454, KAKENHI-PROJECT-21K11330, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-22K19761, KAKENHI-PROJECT-21H04688, KAKENHI-PROJECT-21H04866, KAKENHI-PROJECT-23K24467, KAKENHI-PROJECT-23K27718, KAKENHI-PROJECT-23K27906
[Journal Article] Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents2022
- Author(s)
  Maekawa Takahiro、Sakitani Naoyoshi、Ryu Youngjae、Takashima Atsushi、Murase Shuhei、Fink Julius、Nagao Motoshi、Ogata Toru、Shinohara Masahiro、Sawada Yasuhiro
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: - Issue: 185 Pages: 363100-363100
- DOI
  10.3791/63100
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11330, KAKENHI-PROJECT-22K19761, KAKENHI-PROJECT-21H04866, KAKENHI-PROJECT-20K19367
[Presentation] 脳梗塞モデルマウスに対する垂直方向受動的身体運動介入の効果の検討2025
- Author(s)
  大倉里菜，加藤竜馬，林和寛，中原崚，崎谷直義，伊藤明良
- Organizer
  日本物理療法合同学術大会2025
- Data Source
  KAKENHI-PROJECT-24K02797
[Presentation] 脳梗塞モデルマウスに対する垂直方向受動的身体運動介入の効果の検討2025
- Author(s)
  大倉里菜，加藤竜馬，林和寛，中原崚，崎谷直義，伊藤明良
- Organizer
  日本物理療法合同学術大会2025
- Data Source
  KAKENHI-PROJECT-24K22248
[Presentation] マウス骨折モデルにおける受動的身体運動が疼痛に及ぼす効果2025
- Author(s)
  加藤竜馬，林和寛，中原崚，徐仕軒，趙梓汐，岡田悠里，崎谷直義，伊藤明良
- Organizer
  日本物理療法合同学術大会2025
- Data Source
  KAKENHI-PROJECT-24K22248
[Presentation] メカニカルストレスによる運動の健康増進効果の再現と、その分子メカニズムの解明2024
- Author(s)
  崎谷直義
- Organizer
  第 83 回日本矯正歯科学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K16632
[Presentation] Developing mechanical intervention as a novel strategy to maintain organismal homeostasis based on uncovering the molecular mechanism behind the benefits of exercise2024
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani
- Organizer
  Joint Conference of 　the 22nd Annual Meeting of Asian and Oceanian Myology Center and the 10th Annual Meeting of Japan Muscle Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00682
[Presentation] Uncovering the molecular mechanisms underlying the health benefits of exercise by replicating the effects of exercise with mechanical intervention2024
- Author(s)
  崎谷直義、澤田泰宏
- Organizer
  第46回日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K16632
[Presentation] 生体恒常性維持に作用する運動の正体の少なくとも重要な一部はメカニカルストレスである2024
- Author(s)
  澤田泰宏、崎谷直義
- Organizer
  第97回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K16632
[Presentation] Exercise-mimicking vertically oscillating head motion lowers blood pressure by accelerating interstitial fluid movement in the brain in hypertensive rats and humans2024
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani
- Organizer
  The 52nd Naito Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00682
[Presentation] Challenging muscular dystrophy or dystrophin research via mechanobiological strategy2023
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Takuya Kishi, Keisuke Shinohara, Ayumu Konno, Hirokazu Hirai, Takamasa Sakai, Kohzoh Yoshino, Motoshi Nagao, Masahiro Shinohara
- Organizer
  2023年度筋ジストロフィー研究班会議
- Invited
- Data Source
  KAKENHI-PROJECT-22K19761
[Presentation] 運動で頭部に生じる衝撃は、頭側延髄腹外側野の間質液流動の促進を介して、アストロサイトの機能を制御し、高血圧を改善する2023
- Author(s)
  澤田泰宏, 崎谷直義
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K16632
[Presentation] Challenging muscular dystrophy or dystrophin research via mechanobiological strategy2023
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani, Kouji Takano, Ryosuke Ochi
- Organizer
  2023年度筋ジストロフィー研究班会議
- Invited
- Data Source
  KAKENHI-PROJECT-21H04866
[Presentation] 運動で頭部に生じる衝撃による脳内間質液流動を介した細胞への力学的刺激が高血圧を改善する2023
- Author(s)
  崎谷直義, 澤田泰宏
- Organizer
  第28回日本基礎理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K16632
[Presentation] Brain-targeted mechanical acceleration via passive head motion lowers blood pressure in hypertensive rats and humans2023
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani
- Organizer
  Cell symposia: Molecular mechanisms and integrative physiology of obesity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16632
[Presentation] Brain-targeted mechanical intervention using passive head motion can be antihypertensive2022
- Author(s)
  Yasuhiro SAWADA, Naoyoshi SAKITANI
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04866
[Presentation] Alleviation of hypertension through anti-inflammatory effect of brain-targeted mechanical intervention with passive head motion2022
- Author(s)
  Yasuhiro SAWADA, Naoyoshi SAKITANI
- Organizer
  Keystone Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19761
[Presentation] Alleviation of hypertension through anti-inflammatory effect of brain-targeted mechanical intervention with passive head motion2022
- Author(s)
  Yasuhiro SAWADA, Naoyoshi SAKITANI
- Organizer
  Keystone Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04866
[Presentation] Brain-Targeted Mechanical Intervention Using Passive Head Motion Can Have an Antihypertensive Effect2022
- Author(s)
  Yasuhiro SAWADA, Naoyoshi SAKITANI, Takuya KISHI, Keisuke SHINOHARA, Hirotsugu TSUCHIMOCHI
- Organizer
  American Heart Association Scientific Sessions 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19761
[Presentation] Brain-targeted mechanical intervention using passive head motion can be antihypertensive2022
- Author(s)
  Yasuhiro SAWADA, Naoyoshi SAKITANI
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19761
[Presentation] Brain-targeted Mechanical Intervention with Passive Head Motion Can Have an Antihypertensive Effect2022
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Takuya Kishi, Keisuke Shinohara, Ayumu Konno, Hirokazu Hirai, Takamasa Sakai, Kohzoh Yoshino, Motoshi Nagao, Masahiro Shinohara
- Organizer
  Gordon Research Conferences: Angiotensin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19761
[Presentation] 受動的頭部運動の高血圧改善効果2022
- Author(s)
  澤田泰宏, 崎谷直義
- Organizer
  第10回定量生物学の会
- Data Source
  KAKENHI-PROJECT-22K19761
[Presentation] Brain-Targeted Mechanical Intervention Using Passive Head Motion Can Have an Antihypertensive Effect2022
- Author(s)
  Yasuhiro SAWADA, Naoyoshi SAKITANI, Takuya KISHI, Keisuke SHINOHARA, Hirotsugu TSUCHIMOCHI
- Organizer
  American Heart Association Scientific Sessions 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04866
[Presentation] 受動的頭部運動の高血圧改善効果2022
- Author(s)
  澤田泰宏, 崎谷直義
- Organizer
  第10回定量生物学の会
- Data Source
  KAKENHI-PROJECT-21H04866
[Presentation] Brain-targeted Mechanical Intervention with Passive Head Motion Can Have an Antihypertensive Effect2022
- Author(s)
  Yasuhiro Sawada, Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Takuya Kishi, Keisuke Shinohara, Ayumu Konno, Hirokazu Hirai, Takamasa Sakai, Kohzoh Yoshino, Motoshi Nagao, Masahiro Shinohara
- Organizer
  Gordon Research Conferences: Angiotensin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04866

1. Sawada Yasuhiro (50313135)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. 木戸康平 (50822730)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 土田和可子 (90610014)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 篠原正浩 (60345733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 土屋吉史 (20795679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 伊藤明良 (50762134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 高野弘二 (00510588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 齋藤茂芳 (40583068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 木野久志 (10633406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 吉野大輔 (80624816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 高野晴子 (40532891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 住谷瑛理子 (50724754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 迫圭輔 (50786291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 青木吉嗣 (80534172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 鮎川保則 (50304697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 川内敬子 (40434138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 越智広樹 (30582283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 北嶋康雄 (70734416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 吉岡潔志 (10857262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SAITO Taku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 前川貴郊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakitani Naoyoshi 崎谷 直義

Sakitani Naoyosi 崎谷 直義

Research Projects

Research Products

Co-Researchers

運動模倣力学的刺激による脂肪性肝疾患改善の分子機序解明に基づく、運動の本質の理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

筋萎縮と骨粗鬆症を同時に防ぐ腱を標的とした新たなアプローチ

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

力学の理解に基づく代謝異常症及び認知機能障害に対する革新的治療法開発の基盤構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on Cellular Rehabilitation to Facilitate Cell Replacement Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of Novel Treatment Strategies for Skeletal Muscle Dysfunction in Patients Undergoing Steroid Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

物理療法による超急性期リハビリテーションの創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳内メカニカルストレスに着目した、運動による糖尿病改善効果の分子メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Uncovering the pathogenesis of essential hypertension via mechanobiological approach

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of how mechanical stresses alleviate chronic inflammation of the brain and muscles induced by physical inactivity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering the molecular mechanisms of osteoarthritis by recapitulating the positive effects of exercise on osteoarthritis with mechanical interventionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Biological characterization of breast cancer spheroid formed by fast fabrication method2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histological changes in skeletal muscle induced by heart failure in human patients and animal models: A scoping review2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans2023

Author(s)

Journal Title

DOI

Data Source

Sakitani Naoyoshi 崎谷直義

Sakitani Naoyosi 崎谷直義

[Presentation] 生体恒常性維持に作用する運動の正体の少なくとも重要な一部はメカニカルストレスである2024

[Presentation] 運動で頭部に生じる衝撃は、頭側延髄腹外側野の間質液流動の促進を介して、アストロサイトの機能を制御し、高血圧を改善する2023