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Yamaguchi Toshihiro  山口 敏弘

ORCIDConnect your ORCID iD *help
Researcher Number 50802394
Other IDs
Affiliation (Current) 2025: 東京大学, 医学部附属病院, 届出研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 東京大学, 医学部附属病院, 届出研究員
2018 – 2019: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related
Keywords
Principal Investigator
ドパミン受容体 / 心不全 / D1R / 不整脈 / 心筋細胞 / NF-kB / アポトーシス / 細胞死 / 小胞体ストレス / PET / 放射性トレーサー / D1Rトレーサー … More
Except Principal Investigator
… More 労働生産性 / 睡眠障害 / 頭痛 / SNP / 健康診断 Less
  • Research Projects

    (4 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (9 People)
  •  健診・ゲノムデータを統合したテーラーメイド型ヘルスプロモーションシステムの開発

    • Principal Investigator
      松本 ルミネ
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      The University of Tokyo
  •  Clarification of the mechanism of severe heart failure via cardiac dopamine receptorPrincipal Investigator

    • Principal Investigator
      山口 敏弘
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      The University of Tokyo
  •  Development of new therapy for severe heart failure via cardiac dopamine receptorsPrincipal Investigator

    • Principal Investigator
      山口 敏弘
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  Elucidation of the role of dopamine receptor D1 in the pathophysiology of heart failurePrincipal Investigator

    • Principal Investigator
      Yamaguchi Toshihiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      The University of Tokyo

All 2023 2022 2020

All Journal Article Presentation

  • [Journal Article] Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure2022

    • Author(s)
      Shun Nakamura, Genri Numata, Toshihiro Yamaguchi, Hiroyuki Tokiwa, Yasutomi Higashikuni, Seitaro Nomura, Tetsuo Sasano, Eiki Takimoto, Issei Komuro
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 637 Pages: 247-253

    • DOI

      10.1016/j.bbrc.2022.11.031

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08098, KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-22KJ1202
  • [Journal Article] Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure2020

    • Author(s)
      Yamaguchi Toshihiro、Sumida Tomokazu S.、Nomura Seitaro、Satoh Masahiro、Higo Tomoaki、Ito Masamichi、Ko Toshiyuki、Fujita Kanna、Sweet Mary E.、Sanbe Atsushi、Yoshimi Kenji、Manabe Ichiro、Sasaoka Toshikuni、Taylor Matthew R. G.、Toko Haruhiro、Takimoto Eiki、Naito Atsuhiko T.、Komuro Issei
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 4364-4364

    • DOI

      10.1038/s41467-020-18128-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19H03662, KAKENHI-PROJECT-18K15881
  • [Presentation] ER Stress-Activated NF-kB Signaling Pathway Induces the Upregulation of Cardiomyocyte Dopamine D1 Receptor in Heart Failure2023

    • Author(s)
      Shun Nakamura, Genri Numata, Toshihiro Yamaguchi, Hiroyuki Tokiwa, Yasutomi Higashikuni, Seitaro Nomura, Tetsuo Sasano, Eiki Takimoto, Issei Komuro
    • Organizer
      第87回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08098
  • 1.  松本 ルミネ (10749873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  松崎 博崇 (00782187)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  山道 信毅 (30463897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  岩上 将夫 (30830228)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  岡田 随象 (70727411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  鈴木 顕 (90838806)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  東邦 康智 (10586481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  瀧本 英樹 (20709513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  東口 治弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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