Kuramoto Yuki 藏本勇希

Researcher Number	50843794
Other IDs
Affiliation (Current)	2026: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2026: 大阪大学, 大学院医学系研究科, 招へい教員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2023 – 2025: 大阪大学, 大学院医学系研究科, 招へい教員 2022 – 2024: 大阪大学, 大学院医学系研究科, 特任助教(常勤) 2022: 大阪大学, 大学院医学系研究科, 特任研究員 2019 – 2020: 大阪大学, 医学系研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / 0903:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 心筋エネルギー代謝 / ファブリー病 / ライソソーム / オートファジー / ダノン病 / TFEB活性 / ファブリーモデルマウス / ファブリー心筋症 / 遺伝子解析 / Fabry病 / エネルギー代謝 / iPS細胞 … More Except Principal Investigator … More 心筋症 / 拡張型心筋症 / 創薬標的 / 病態解明 / ゲノム医療 / 病態機序 / リスク因子 / 病原性バリアント / 全ゲノム解析 Less

Elucidation of the pathophysiology of cardiomyopathy and exploration of new drug targets for realization of genomic medicine
- Principal Investigator
  
  朝野仁裕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Radiomics及びRadiogenomicsを用いた拡張型心筋症の革新的予後予測因子の探索
- Principal Investigator
  
  井手盛子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Osaka
Elucidation of molecular mechanism of LAMP2 independent autophagy in Danon cardiomyoopathy.Principal Investigator
- Principal Investigator
  
  藏本勇希
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Investigation of the mechanism of Fabry cardiomyopathy from the association between TFEB activity and dysfunction in energy metabolism.Principal Investigator
- Principal Investigator
  
  Kuramoto Yuki
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Integrative functional analysis based on whole-genome sequencing for the identification of novel cardiomyopathy genes and elucidation of their pathogenic mechanisms
- Principal Investigator
  
  Asano Yoshihiro
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Revealing the mechanism of Fabry cardiomyopathy by analyzing energy metabolism.Principal Investigator
- Principal Investigator
  
  Kuramoto Yuki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  Osaka University

All 2025 2023 2022 2019

All Journal Article Presentation

[Journal Article] Human leukocyte antigen-DQ risk heterodimeric haplotypes of left ventricular dysfunction in cardiac sarcoidosis: an autoimmune view of its role.2023
- Author(s)
  Yamamoto H, Miyashita Y, Minamiguchi H, Hosomichi K, Yoshida S, Kioka H, Shinomiya H, Nagata H, Onoue K, Kawasaki M, Kuramoto Y, Nomura A, Toma Y, Watanabe T, Yamada T, Ishihara Y, Nagata M, Kato H, Hakui H, Saito Y, Asano Y, Sakata Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19767-19767
- DOI
  10.1038/s41598-023-46915-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16103, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-23K24328
[Journal Article] Clinical Outcomes and Genetic Analyses of Restrictive Cardiomyopathy in Children2023
- Author(s)
  Ishida Hidekazu、Narita Jun、Ishii Ryo、Suginobe Hidehiro、Tsuru Hirofumi、Wang Renjie、Yoshihara Chika、Ueyama Atsuko、Ueda Kazutoshi、Hirose Masaki、Hashimoto Kazuhisa、Nagano Hiroki、Kogaki Shigetoyo、Kuramoto Yuki、Miyashita Yohei、Asano Yoshihiro、Ozono Keiichi
- Journal Title
  
  Circulation: Genomic and Precision Medicine
  
  Volume: 16 Issue: 4 Pages: 382-389
- DOI
  10.1161/circgen.122.004054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24328
[Journal Article] Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin2023
- Author(s)
  Hitsumoto T, Tsukamoto O, Matsuoka K, Li J, Liu L, Kuramoto Y, Higo S, Ogawa S, Fujino N, Yoshida S, Kioka H, Kato H, Hakui H, Saito Y, Okamoto C, Inoue H, Hyejin J, Ueda K, Segawa T, Nishimura S, Asano Y, Asanuma H, Tani A, Imamura R, Komagawa S, Kanai T, Takamura M, Sakata Y, Kitakaze M, Haruta JI, Takashima S.
- Journal Title
  
  Circulation
  
  Volume: - Issue: 25 Pages: 1902-1918
- DOI
  10.1161/circulationaha.122.062885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-23KJ1480, KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-20H03927, KAKENHI-PROJECT-23K24327, KAKENHI-PROJECT-22K08142, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-23K24328
[Journal Article] Cardiac Magnetic Resonance Imaging Findings in Filamin C Variant-Associated Arrhythmogenic Left Ventricular Cardiomyopathy2023
- Author(s)
  Yoshimura Fumihiro、Oda Seitaro、Kidoh Masafumi、Hayashi Hidetaka、Yonemura Mari、Miyazaki Shuhei、Takashio Seiji、Kuramoto Yuki、Asano Yoshihiro、Tsujita Kenichi、Hirai Toshinori
- Journal Title
  
  Circ J
  
  Volume: 87 Issue: 10 Pages: 1403
- DOI
  10.1253/circj.CJ-23-0480
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2023-09-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24328
[Journal Article] End-stage Hypertrophic Cardiomyopathy with Advanced Heart Failure in Patients Carrying <i>MYH7</i> R453 Variants: A Case Series2023
- Author(s)
  Naito Susumu、Higo Shuichiro、Kameda Satoshi、Ogawa Shou、Tabata Tomoka、Akazawa Yasuhiro、Nakamura Daisuke、Nakamoto Kei、Sera Fusako、Kuramoto Yuki、Aasano Yoshihiro、Hikoso Shungo、Miyagawa Shigeru、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 21 Pages: 3167-3173
- DOI
  10.2169/internalmedicine.1497-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-23K24328
[Journal Article] Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series2022
- Author(s)
  Tabata Tomoka、Kuramoto Yuki、Ohtani Tomohito、Miyawaki Hiroshi、Miyashita Yohei、Sera Fusako、Kioka Hidetaka、Higo Shuichiro、Asano Yoshihiro、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 13 Pages: 1987-1993
- DOI
  10.2169/internalmedicine.8594-21
- NAID
  130008130223
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-23K24328, KAKENHI-PROJECT-19H03652
[Journal Article] Refractory Ventricular Arrhythmias in a Patient With Dilated Cardiomyopathy Caused by a Nonsense Mutation in <i>BAG5</i>2022
- Author(s)
  Hakui Hideyuki、Kioka Hidetaka、Sera Fusako、Nakamoto Kei、Ozu Kentaro、Kuramoto Yuki、Miyashita Yohei、Ohtani Tomohito、Hikoso Shungo、Asano Yoshihiro、Sakata Yasushi
- Journal Title
  
  Circ J
  
  Volume: 86 Issue: 12 Pages: 2043
- DOI
  10.1253/circj.CJ-22-0329
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2022-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-22K20919, KAKENHI-PROJECT-23K24328
[Presentation] 両アレル性KLHL24バリアントによる重症肥大型心筋症を来した2家系の報告2025
- Author(s)
  江藤良、藏本勇希、赤澤康裕、宮下洋平、中村大輔、世良英子、大谷朋仁、朝野仁裕、坂田泰史
- Organizer
  第11回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-22K16138
[Presentation] ゲノム医療問診票による心筋症患者の価値観及び遺伝子解析に対する考え方の調査2025
- Author(s)
  藏本勇希、江藤良、赤澤康裕、中村大輔、世良英子、木岡秀隆、肥後修一朗、大谷朋仁、朝野仁裕、坂田泰史
- Organizer
  第11回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-22K16138
[Presentation] Arrhythmogenic Cardiomyopathy-related Pathogenic Variants as Independent Risk Factors for Sustained Ventricular Arrhythmias in Dilated Cardiomyopathy after Left Ventricular Assist Device Implantation2025
- Author(s)
  Ryo Eto, Yuki Kuramoto, Yasuhiro Akazawa, Yohei, Miyashita, Daisuke Nakamura,Akira Yoshida, Fusako Sera, Takafumi Oka, Tomohito Ohtani, Yoshihiro Asano, Yasushi Sakata
- Organizer
  第89回日本循環器学会
- Data Source
  KAKENHI-PROJECT-22K16138
[Presentation] 不整脈原性心筋症関連病原性バリアントは左室補助人工心臓植込み後の持続性心室不整脈の予測因子である2025
- Author(s)
  江藤良、藏本勇希、赤澤康裕、宮下洋平、中村大輔、世良英子、岡崇史、大谷朋仁、朝野仁裕、坂田泰史
- Organizer
  第11回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-22K16138
[Presentation] Understanding the Values and Perspectives on Genetic Analysis in Cardiovascular Patients through a Genomic Medicine Questionnaire.2025
- Author(s)
  Yuki Kuramoto, Ryo Eto, Yasuhiro Akazawa, Daisuke Nakamura, Fusako Sera, Hidetaka Kioka, Shuichiro Higo, Tomohito Ohtani, Yoshihiro Asano, Yasushi Sakata
- Organizer
  第89回日本循環器学会
- Data Source
  KAKENHI-PROJECT-22K16138
[Presentation] Disorders in energy metabolism are associated with pathophysiology of Fabry cardiomyopathy unable to be treated by enzyme replacement therapy.2019
- Author(s)
  藏本勇希、朝野仁裕、李鍾國、坂田泰史
- Organizer
  第36回国際心臓研究学会日本部会
- Data Source
  KAKENHI-PROJECT-19K23984

1. Asano Yoshihiro (60527670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 四宮春輝 (10908213)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 宮下洋平 (60816312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 高島成二 (90379272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 井手盛子 (90624247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 溝手勇 (10584609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 増山潔 (30838967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中村大輔 (30869970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 奥野翔太 (81000479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KATO Hisakazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuramoto Yuki 藏本 勇希

Research Projects

Research Products

Co-Researchers

Elucidation of the pathophysiology of cardiomyopathy and exploration of new drug targets for realization of genomic medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Radiomics及びRadiogenomicsを用いた拡張型心筋症の革新的予後予測因子の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism of LAMP2 independent autophagy in Danon cardiomyoopathy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the mechanism of Fabry cardiomyopathy from the association between TFEB activity and dysfunction in energy metabolism.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrative functional analysis based on whole-genome sequencing for the identification of novel cardiomyopathy genes and elucidation of their pathogenic mechanisms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Revealing the mechanism of Fabry cardiomyopathy by analyzing energy metabolism.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Human leukocyte antigen-DQ risk heterodimeric haplotypes of left ventricular dysfunction in cardiac sarcoidosis: an autoimmune view of its role.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Outcomes and Genetic Analyses of Restrictive Cardiomyopathy in Children2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cardiac Magnetic Resonance Imaging Findings in Filamin C Variant-Associated Arrhythmogenic Left Ventricular Cardiomyopathy2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] End-stage Hypertrophic Cardiomyopathy with Advanced Heart Failure in Patients Carrying <i>MYH7</i> R453 Variants: A Case Series2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series2022

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

Kuramoto Yuki 藏本勇希

[Presentation] 不整脈原性心筋症関連病原性バリアントは左室補助人工心臓植込み後の持続性心室不整脈の予測因子である2025